sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1ozh | HE3 | Acetolactate synthase, catabolic | 2.2.1.6 | 1.000 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.528 | |
| 4ejg | NCT | Cytochrome P450 2A13 | 1.14.14.1 | 0.498 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.495 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.494 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.493 | |
| 3le6 | 2BZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.493 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.491 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.489 | |
| 3ih0 | ANP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.488 | |
| 4bdc | ODH | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.488 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.488 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.486 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.485 | |
| 2vtr | LZB | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.485 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.485 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.485 | |
| 4anb | YQY | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.485 | |
| 1iwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.484 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.484 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.483 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.483 | |
| 2r3j | SCJ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.482 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.482 | |
| 4cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.482 | |
| 1s5k | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.481 | |
| 3pgp | ACO | Uncharacterized protein | / | 0.481 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.480 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.479 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.479 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.479 | |
| 5ahk | TPP | Acetolactate synthase II, large subunit | / | 0.479 | |
| 2q5o | PPY | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.478 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.478 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.477 | |
| 3rm6 | 18Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.477 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.477 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.477 | |
| 2y9q | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.476 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.476 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.475 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.475 | |
| 3uzp | 0CK | Casein kinase I isoform delta | 2.7.11.1 | 0.475 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.475 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.475 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.475 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.475 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.474 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.474 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.474 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.474 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.474 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.474 | |
| 1t2d | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.473 | |
| 3cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.473 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.473 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.473 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.473 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.472 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.472 | |
| 4q1x | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 1e1x | NW1 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.471 | |
| 1me8 | RVP | Inosine-5'-monophosphate dehydrogenase | / | 0.471 | |
| 1t3r | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.471 | |
| 1y4l | SVR | Basic phospholipase A2 homolog 2 | / | 0.471 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.471 | |
| 3gob | HXX | DdmC | / | 0.471 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.471 | |
| 4cf1 | IY7 | Integrase | / | 0.471 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.471 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.471 | |
| 1gqt | ACP | Ribokinase | / | 0.470 | |
| 2vto | LZ8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.470 | |
| 3mj5 | GRM | Replicase polyprotein 1a | 3.4.22 | 0.470 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.470 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.469 | |
| 3f8k | COA | Uncharacterized protein | / | 0.469 | |
| 3had | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.469 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.469 | |
| 3zuy | TCH | Transporter | / | 0.469 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.469 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.469 | |
| 3el5 | 1UN | Gag-Pol polyprotein | / | 0.468 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.468 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.468 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.468 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4fkt | 48K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.468 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.468 | |
| 4oau | ADP | 2-5A-dependent ribonuclease | 3.1.26 | 0.468 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.467 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.467 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.467 | |
| 3zpt | M8Y | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.467 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4l4d | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.467 | |
| 4lop | SB4 | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.466 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.466 | |
| 2ci0 | 1CM | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.466 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.466 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.466 | |
| 2owu | SAH | Diphthine synthase | / | 0.466 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.466 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.466 | |
| 4an9 | 2P7 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.466 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.466 | |
| 1iwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.465 | |
| 1ke7 | LS3 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.465 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.465 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.465 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.465 | |
| 4b7x | NAP | Probable oxidoreductase | / | 0.465 | |
| 5eai | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.464 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.464 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.464 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.464 | |
| 2pvy | ACP | Fibroblast growth factor receptor 2 | / | 0.464 | |
| 2vo6 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 2vtt | LZD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.464 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.464 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.464 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.464 | |
| 3tri | NAP | Pyrroline-5-carboxylate reductase | / | 0.464 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.464 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.464 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.464 | |
| 4l6g | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.464 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.464 | |
| 4nfh | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 5cdt | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.463 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2bgi | FAD | NADPH:ferredoxin reductase | / | 0.463 | |
| 2e8h | SAH | Diphthine synthase | / | 0.463 | |
| 2ejj | SAH | Diphthine synthase | / | 0.463 | |
| 2hjr | APR | Malate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase | / | 0.463 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.463 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.463 | |
| 3da1 | FAD | Glycerol-3-phosphate dehydrogenase | / | 0.463 | |
| 3elj | GS7 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.463 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.463 | |
| 4fkv | 61K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.463 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.463 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.463 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.463 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 1g6c | IFP | Thiamine-phosphate synthase | / | 0.462 | |
| 1qp8 | NDP | 2-hydroxyacid dehydrogenase | / | 0.462 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.462 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.462 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.462 | |
| 2ek3 | SAH | Diphthine synthase | / | 0.462 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.462 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.462 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.462 | |
| 3r1y | X76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.462 | |
| 4gev | CB3 | Thymidylate synthase | / | 0.462 | |
| 4zca | ADP | Kinesin-like protein KIF11 | / | 0.462 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1ec3 | MS3 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 1v9a | SAH | Uncharacterized protein | / | 0.461 | |
| 2el0 | SAH | Diphthine synthase | / | 0.461 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2qhm | 7CS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.461 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.461 | |
| 3em6 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.461 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.461 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.461 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.461 | |
| 1aj2 | 2PH | Dihydropteroate synthase | / | 0.460 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.460 | |
| 1geb | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.460 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.460 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 1wng | SAH | Diphthine synthase | / | 0.460 | |
| 1y91 | CT9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2dsg | SAH | Diphthine synthase | / | 0.460 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.460 | |
| 2iw8 | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3dnd | LL2 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 3fwi | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.460 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3rpo | 24Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.460 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.460 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.460 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.460 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.460 | |
| 1bdr | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.459 | |
| 1r6g | 442 | Thyroid hormone receptor beta | / | 0.459 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.459 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.459 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.459 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.459 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.459 | |
| 2dxv | SAH | Diphthine synthase | / | 0.459 | |
| 2eq7 | NAD | Dihydrolipoyl dehydrogenase | / | 0.459 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.459 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.459 | |
| 2pan | TDP | Glyoxylate carboligase | 4.1.1.47 | 0.459 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.459 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 3saa | 77F | Protease | / | 0.459 | |
| 4a33 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.459 | |
| 4egn | TWO | Cytochrome P450 | / | 0.459 | |
| 4iqk | IQK | Kelch-like ECH-associated protein 1 | / | 0.459 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.459 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.459 | |
| 1c70 | L75 | Protease | / | 0.458 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 1me7 | MOA | Inosine-5'-monophosphate dehydrogenase | / | 0.458 | |
| 1oir | HDY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1u54 | ACP | Activated CDC42 kinase 1 | / | 0.458 | |
| 2a0c | CK9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 2ceo | T44 | Thyroxine-binding globulin | / | 0.458 | |
| 2dek | SAH | Diphthine synthase | / | 0.458 | |
| 2qi4 | MZ6 | Gag-Pol polyprotein | / | 0.458 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.458 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.458 | |
| 3r8l | Z30 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.458 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.458 | |
| 4cfa | WOP | Integrase | / | 0.458 | |
| 4dqc | 017 | Gag-Pol polyprotein | / | 0.458 | |
| 4fki | 09K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.458 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.458 | |
| 4lfi | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.458 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.458 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.458 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.457 | |
| 1ppj | ANY | Cytochrome b | / | 0.457 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.457 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.457 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.457 | |
| 2qhy | MZ1 | Gag-Pol polyprotein | / | 0.457 | |
| 2qi0 | MZ3 | Gag-Pol polyprotein | / | 0.457 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.457 | |
| 2z6r | SAH | Diphthine synthase | / | 0.457 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.457 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.457 | |
| 3o9i | A61 | Gag-Pol polyprotein | / | 0.457 | |
| 3u9e | COA | Lmo1369 protein | / | 0.457 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.457 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.457 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.457 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.457 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.457 | |
| 4lx9 | ACO | N-alpha-acetyltransferase | 2.3.1 | 0.457 | |
| 4pan | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.457 | |
| 4q0a | 4OA | Vitamin D3 receptor A | / | 0.457 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.457 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.456 | |
| 1qvn | FRI | Interleukin-2 | / | 0.456 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1yw2 | PGJ | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.456 | |
| 2h12 | CMX | Citrate synthase | / | 0.456 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.456 | |
| 2pd8 | FAD | Vivid PAS protein VVD | / | 0.456 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.456 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.456 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.456 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.456 | |
| 3qtu | X44 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.456 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.456 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.456 | |
| 4ijp | 1EH | Serine/threonine-protein kinase PRP4 homolog | 2.7.11.1 | 0.456 | |
| 4jr7 | GNP | Casein kinase II subunit alpha | 2.7.11.1 | 0.456 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.456 | |
| 4ucn | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.456 | |
| 1dc6 | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.455 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.455 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 1upa | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.455 | |
| 1wbp | ADP | SRSF protein kinase 1 | 2.7.11.1 | 0.455 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 2hwr | DRD | Peroxisome proliferator-activated receptor gamma | / | 0.455 | |
| 2ihv | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.455 | |
| 2jkq | VG8 | Focal adhesion kinase 1 | 2.7.10.2 | 0.455 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.455 | |
| 2p33 | J07 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.455 | |
| 2w0j | ZAT | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.455 | |
| 2wuf | KEM | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.455 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.455 | |
| 3zlx | 5EZ | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.455 | |
| 4a1z | ADP | Kinesin-like protein KIF11 | / | 0.455 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 4l4b | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 4qpm | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.455 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.455 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.454 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.454 | |
| 3eek | 53S | Uncharacterized protein | / | 0.454 | |
| 3eya | TDP | Pyruvate dehydrogenase [ubiquinone] | 1.2.5.1 | 0.454 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.454 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 3pjt | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.454 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.454 | |
| 3rni | 21Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 3stu | DK3 | Methylketone synthase I | / | 0.454 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.454 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.454 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.454 | |
| 4e2b | FMN | Dehydrogenase | / | 0.454 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.454 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.454 | |
| 4loq | SB4 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1v1b | ATP | 2-dehydro-3-deoxygluconokinase | 2.7.1.45 | 0.453 | |
| 2a1n | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.453 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.453 | |
| 2q64 | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3o9a | K14 | Pol polyprotein | / | 0.453 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3t2z | FAD | Sulfide-quinone reductase | / | 0.453 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.453 | |
| 4bib | IEO | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 4c2u | ANP | DNA helicase | / | 0.453 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1 | / | 0.453 | |
| 4dx9 | SER_ALA_VAL_THR | Integrin beta-1-binding protein 1 | / | 0.453 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.453 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.453 | |
| 4fkp | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4q73 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 4qmz | B49 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.453 | |
| 5dt4 | ATP | Aurora kinase A | 2.7.11.1 | 0.453 | |
| 1c6y | MK1 | Protease | / | 0.452 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.452 | |
| 1hvi | A77 | Protease | / | 0.452 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.452 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.452 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.452 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.452 | |
| 2btr | U73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.452 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.452 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.452 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.452 | |
| 2pmn | K51 | Protein kinase 7 | / | 0.452 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.452 | |
| 2zgz | GNP | Plasmid segregation protein ParM | / | 0.452 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.452 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.452 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.452 | |
| 3ocp | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.452 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.452 | |
| 4aqc | 88A | Tyrosine-protein kinase JAK2 | / | 0.452 | |
| 4dn5 | AGS | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.452 | |
| 4fk8 | FAD | Ferredoxin--NADP reductase | / | 0.452 | |
| 4fkj | 11K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4fko | 20K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4jbi | NDP | Alcohol dehydrogenase (Zinc) | / | 0.452 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.452 | |
| 4kb8 | 1QN | Casein kinase I isoform delta | 2.7.11.1 | 0.452 | |
| 4lrz | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.452 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.452 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.452 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.451 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1g5s | I17 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 1hwr | 216 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.451 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.451 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 2b1p | AIZ | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 2c6o | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 2exc | JNK | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.451 | |
| 2hut | SAH | Diphthine synthase | / | 0.451 | |
| 2i0d | MUT | Protease | / | 0.451 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 2upj | U02 | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 2w06 | FRV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.451 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.451 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.451 | |
| 3lt2 | FT3 | Enoyl-ACP reductase | / | 0.451 | |
| 3qx4 | X4B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3ral | 04Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3rk9 | 09Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
| 3tku | M77 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.451 | |
| 3v9y | 24L | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.451 | |
| 4d0l | 093 | Phosphatidylinositol 4-kinase beta | 2.7.1.67 | 0.451 | |
| 4f9m | FCM | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 4jaj | XU1 | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 4l52 | 1UL | Mitogen-activated protein kinase kinase kinase 7 | 2.7.11.25 | 0.451 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.451 | |
| 4xuh | SFI | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.450 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.450 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.450 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.450 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 1owm | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.450 | |
| 2pch | SAH | Diphthine synthase | / | 0.450 | |
| 2r3l | SCW | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 2vxo | XMP | GMP synthase [glutamine-hydrolyzing] | 6.3.5.2 | 0.450 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.450 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3hmm | 855 | TGF-beta receptor type-1 | 2.7.11.30 | 0.450 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.450 | |
| 3r83 | Z14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.450 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.450 | |
| 4eh9 | 0OQ | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.450 | |
| 4i0s | 1B5 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.450 | |
| 4qml | ANP | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.450 | |
| 4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.450 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.450 | |
| 5kcz | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.449 | |
| 1fvv | 107 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1s22 | ATP | Actin, alpha skeletal muscle | / | 0.449 | |
| 1sbg | IM1 | Gag-Pol polyprotein | / | 0.449 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.449 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.449 | |
| 2ele | SAH | Diphthine synthase | / | 0.449 | |
| 2p6l | SAH | Diphthine synthase | / | 0.449 | |
| 2pwc | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.449 | |
| 2w1d | L0D | Aurora kinase A | 2.7.11.1 | 0.449 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.449 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.449 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.449 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.449 | |
| 3ka0 | MK3 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.449 | |
| 3r2b | 05B | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.449 | |
| 3r5z | F42 | Uncharacterized protein | / | 0.449 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.449 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.449 | |
| 4aw1 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 4b4d | FAD | Ferredoxin-NADP reductase | / | 0.449 | |
| 4bi0 | Z0W | Dual specificity protein kinase TTK | 2.7.12.1 | 0.449 | |
| 4bl1 | ANP | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.449 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.449 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4dqf | 017 | Gag-Pol polyprotein | / | 0.449 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4ftu | 7HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.449 | |
| 4jxr | ACO | Acetyltransferase | / | 0.449 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.449 | |
| 5a3c | NAD | SIR2 family protein | / | 0.449 | |
| 5da9 | AGS | Uncharacterized protein | / | 0.449 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.448 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.448 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.448 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.448 | |
| 1um0 | FMN | Chorismate synthase | / | 0.448 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.448 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2egl | SAH | Diphthine synthase | / | 0.448 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.448 | |
| 2hbh | XE4 | Vitamin D3 receptor A | / | 0.448 | |
| 2j5x | GSP | ADP-ribosylation factor 6 | / | 0.448 | |
| 2pg8 | YE1 | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase | / | 0.448 | |
| 2psu | MUU | Protease | / | 0.448 | |
| 2pvn | P63 | Casein kinase II subunit alpha | 2.7.11.1 | 0.448 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.448 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.448 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.448 | |
| 3du8 | 553 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.448 | |
| 3iae | D7K | Benzaldehyde lyase | / | 0.448 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 3lfq | A28 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.448 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.448 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 3v9v | 21L | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 4a06 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.448 | |
| 4cql | NAD | Estradiol 17-beta-dehydrogenase 8 | 1.1.1.62 | 0.448 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.448 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.448 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.448 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.448 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.448 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 4lht | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.448 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.448 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.448 | |
| 5dt0 | SKE | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.448 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.448 | |
| 1c6z | ROC | Protease | / | 0.447 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.447 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.447 | |
| 1ihx | SND | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.447 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.447 | |
| 1zeo | C01 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.447 | |
| 2e08 | SAH | Diphthine synthase | / | 0.447 | |
| 2ek7 | SAH | Diphthine synthase | / | 0.447 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.447 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.447 | |
| 2qi6 | MZ8 | Gag-Pol polyprotein | / | 0.447 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.447 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.447 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 2xk9 | XK9 | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.447 | |
| 2yww | ATP | Aspartate carbamoyltransferase regulatory chain | / | 0.447 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3kn5 | ANP | Ribosomal protein S6 kinase alpha-5 | 2.7.11.1 | 0.447 | |
| 3lki | ATP | Fructokinase | / | 0.447 | |
| 3o9g | F53 | Gag-Pol polyprotein | / | 0.447 | |
| 3o9h | K2E | Gag-Pol polyprotein | / | 0.447 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3oy4 | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3py0 | SU9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.447 | |
| 3ufn | ROC | Gag-Pol polyprotein | / | 0.447 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.447 | |
| 3v8w | 0G2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.447 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.447 | |
| 3wrm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.447 | |
| 4isk | UMP | Thymidylate synthase | / | 0.447 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.447 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4l4a | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.447 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.447 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.447 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.447 | |
| 1a9m | U0E | Gag-Pol polyprotein | / | 0.446 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.446 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.446 | |
| 1g6c | TZP | Thiamine-phosphate synthase | / | 0.446 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.446 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.446 | |
| 1sn5 | T3 | Transthyretin | / | 0.446 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.446 | |
| 1u3w | FXY | Alcohol dehydrogenase 1C | 1.1.1.1 | 0.446 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.446 | |
| 1xny | BTN | Propionyl-CoA carboxylase complex B subunit | / | 0.446 | |
| 1ykr | 628 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1z1r | HBH | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 2c6t | DT5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2ds1 | 1CD | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 2fto | TMP | Thymidylate synthase | / | 0.446 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.446 | |
| 2hs1 | 017 | Protease | / | 0.446 | |
| 2i4x | KGQ | Protease | / | 0.446 | |
| 2jkk | BI9 | Focal adhesion kinase 1 | 2.7.10.2 | 0.446 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.446 | |
| 2qi5 | MZ7 | Gag-Pol polyprotein | / | 0.446 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.446 | |
| 3djk | G55 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3ec0 | GRL | Gag-Pol polyprotein | 3.4.23.47 | 0.446 | |
| 3efw | AK8 | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 3ekv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3eky | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3ggj | 25H | Hypoxanthine-guanine phosphoribosyltransferase | 2.4.2.8 | 0.446 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.446 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.446 | |
| 3mxd | K53 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3nu9 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3owl | 19E | Casein kinase II subunit alpha | 2.7.11.1 | 0.446 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.446 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 4ek1 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.446 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.446 | |
| 4fkr | 45K | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 4fv6 | E57 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 4idt | T28 | Mitogen-activated protein kinase kinase kinase 14 | 2.7.11.25 | 0.446 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.446 | |
| 4l98 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.446 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.446 | |
| 4q1w | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.446 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.446 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.446 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.445 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1hw5 | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.445 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.445 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1pzg | A3D | Lactate dehydrogenase | / | 0.445 | |
| 1q41 | IXM | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.445 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.445 | |
| 2a4l | RRC | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 2bhi | SFT | Cytotoxin 3 | / | 0.445 | |
| 2bxq | IMN | Serum albumin | / | 0.445 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.445 | |
| 2jd1 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.445 | |
| 2nyu | SAM | rRNA methyltransferase 2, mitochondrial | / | 0.445 | |
| 2p5c | SAH | Diphthine synthase | / | 0.445 | |
| 2v4l | ABJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.445 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.445 | |
| 2wtd | ZZK | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 3b2e | ADP | ATPase GET3 | / | 0.445 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.445 | |
| 3bva | 2NC | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3dr8 | ACO | L-methionine sulfoximine/L-methionine sulfone acetyltransferase | / | 0.445 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3nls | 016 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3nwx | KVS | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3qzi | X72 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3rk7 | 08Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3rkb | 12Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3zm4 | 22T | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4acg | 6LQ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.445 | |
| 4an2 | EUI | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.445 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.445 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.445 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.445 | |
| 4dqe | 017 | Gag-Pol polyprotein | / | 0.445 | |
| 4ewh | T77 | Activated CDC42 kinase 1 | / | 0.445 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.445 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.445 | |
| 4ysw | FAD | Xanthine dehydrogenase/oxidase | / | 0.445 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.445 | |
| 5kj6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.445 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.444 | |
| 1ivq | 0PX | Gag-Pol polyprotein | / | 0.444 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.444 | |
| 1mru | AGS | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.444 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.444 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.444 | |
| 2c6k | DT2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2cgw | 3C3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2e07 | SAH | Diphthine synthase | / | 0.444 | |
| 2f8g | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.444 | |
| 2gsd | NAD | Formate dehydrogenase | / | 0.444 | |
| 2hb3 | GRL | Protease | / | 0.444 | |
| 2oor | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.444 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.444 | |
| 2vth | LZ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2vv9 | IM9 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3ggu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.444 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.444 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.444 | |
| 3k5u | PFQ | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 3nuu | JOZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3nwz | COA | BH2602 protein | / | 0.444 | |
| 3o9d | K19 | Pol polyprotein | / | 0.444 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.444 | |
| 3rpr | 25Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3ttj | JBI | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.444 | |
| 3tz3 | B36 | Acetyl-CoA carboxylase | / | 0.444 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 4c2x | NHW | Glycylpeptide N-tetradecanoyltransferase 2 | / | 0.444 | |
| 4heg | G52 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 4hgl | 0YO | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.444 | |
| 4jbo | WPH | Aurora kinase A | 2.7.11.1 | 0.444 | |
| 4l4x | NDP | AmphI | / | 0.444 | |
| 4l7f | 1V5 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.444 | |
| 4nm9 | FAD | Bifunctional protein PutA | / | 0.444 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.444 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.444 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.444 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 1eby | BEB | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1eio | GCH | Gastrotropin | / | 0.443 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.443 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.443 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.443 | |
| 1t7i | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 2bb9 | AKC | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2bxm | IMN | Serum albumin | / | 0.443 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.443 | |
| 2e17 | SAH | Diphthine synthase | / | 0.443 | |
| 2euf | LQQ | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.443 | |
| 2h96 | 893 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.443 | |
| 2i0a | MUI | Protease | / | 0.443 | |
| 2qbn | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.443 | |
| 2yir | YIR | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.443 | |
| 3bto | SSB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 3hdm | MMG | Serine/threonine-protein kinase Sgk1 | 2.7.11.1 | 0.443 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.443 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.443 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.443 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3pe6 | ZYH | Monoglyceride lipase | / | 0.443 | |
| 3u2x | ASO | Glycogenin-1 | 2.4.1.186 | 0.443 | |
| 3uk6 | ADP | RuvB-like 2 | 3.6.4.12 | 0.443 | |
| 3umv | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.443 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 4f70 | 0ST | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.443 | |
| 4fkl | CK2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.443 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.443 | |
| 4qo9 | 627 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.443 | |
| 5d4v | SAH | Uncharacterized protein MJ0489 | / | 0.443 | |
| 5dr6 | SKE | Aurora kinase A | 2.7.11.1 | 0.443 | |
| 5hws | NAP | 2-dehydropantoate 2-reductase | / | 0.443 | |
| 1aq1 | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.442 | |
| 1hxw | RIT | Gag-Pol polyprotein | / | 0.442 | |
| 1ii6 | ADP | Kinesin-like protein KIF11 | / | 0.442 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.442 | |
| 1o6y | ACP | Serine/threonine-protein kinase PknB | 2.7.11.1 | 0.442 | |
| 1ohr | 1UN | V-1 PROTEASE protein | / | 0.442 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.442 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.442 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.442 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2e8q | SAH | Diphthine synthase | / | 0.442 | |
| 2fde | 385 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.442 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.442 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.442 | |
| 2wpw | ACO | Orf14 | / | 0.442 | |
| 2xch | CKG | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2y3r | TIR | TamL | / | 0.442 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.442 | |
| 3cgd | COA | Coenzyme A disulfide reductase | / | 0.442 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.442 | |
| 3el1 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.442 | |
| 3ggf | GVD | Serine/threonine-protein kinase 26 | / | 0.442 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.442 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.442 | |
| 3lzv | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 3myk | BIT | Myosin-2 heavy chain | / | 0.442 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3os3 | 3OS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.442 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3qqg | X06 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3so9 | 017 | Pol protein | / | 0.442 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.442 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.442 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.442 | |
| 4e2d | FMN | Dehydrogenase | / | 0.442 | |
| 4e5y | NDP | GDP-L-fucose synthase | 1.1.1.271 | 0.442 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4hbn | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.442 | |
| 4izy | 1J2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4k7y | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.442 | |
| 4mxx | DB8 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.442 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.442 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.442 | |
| 4utd | ACP | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.442 | |
| 1b6p | PI7 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.441 | |
| 1pmv | 537 | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.441 | |
| 1x8v | ESL | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.441 | |
| 2ag0 | TPP | Benzaldehyde lyase | / | 0.441 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.441 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.441 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.441 | |
| 2fsv | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.441 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.441 | |
| 2huq | SAH | Diphthine synthase | / | 0.441 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.441 | |
| 2pcm | SAH | Diphthine synthase | / | 0.441 | |
| 2pym | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2vx0 | 7X7 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.441 | |
| 2y3r | TRK | TamL | / | 0.441 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3bxr | DRR | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.441 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3fz1 | B98 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.441 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3lxi | CAM | Cytochrome P450 | / | 0.441 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.441 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3pxk | PXK | Focal adhesion kinase 1 | 2.7.10.2 | 0.441 | |
| 3qaa | G04 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.441 | |
| 3up3 | XCA | aceDAF-12 | / | 0.441 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.441 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 3zux | TCH | Transporter | / | 0.441 | |
| 4an3 | 5Y0 | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.441 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.441 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4cgi | NZL | Integrase | / | 0.441 | |
| 4gb2 | 0LQ | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4l8u | 9AZ | Serum albumin | / | 0.441 | |
| 4nk9 | 2K5 | Fibroblast growth factor receptor 1 | / | 0.441 | |
| 4qgi | ROC | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 4qjq | OTR | Lactoperoxidase | / | 0.441 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.441 | |
| 5a27 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 5ag7 | MYA | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 5c3y | AN2 | Ribokinase | / | 0.441 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.441 | |
| 1aj8 | COA | Citrate synthase | / | 0.440 | |
| 1gii | 1PU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1hos | PHP | Gag-Pol polyprotein | / | 0.440 | |
| 1k6t | XN1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.440 | |
| 1nsf | ATP | Vesicle-fusing ATPase | 3.6.4.6 | 0.440 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1pxl | CK4 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.440 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.440 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1siv | PSI | Gag-Pol polyprotein | / | 0.440 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1tcw | IM1 | Gag-Pol polyprotein | / | 0.440 | |
| 1wlv | COA | Phenylacetic acid degradation protein PaaI | / | 0.440 | |
| 1x15 | NAD | NAD(P) transhydrogenase subunit alpha | 1.6.1.2 | 0.440 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.440 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.440 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2egs | SAH | Diphthine synthase | / | 0.440 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.440 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.440 | |
| 2q54 | MU1 | Protease | / | 0.440 | |
| 2qd7 | 065 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2r3w | G3G | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2uxz | HI1 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.440 | |
| 2yer | TQ1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2yyi | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.440 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.440 | |
| 2zui | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3b9l | AZZ | Serum albumin | / | 0.440 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3cyw | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3dck | KVI | Protease | / | 0.440 | |
| 3el9 | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
| 3ori | AGS | Serine/threonine protein kinase | / | 0.440 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.440 | |
| 3qd3 | 3Q5 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 3r7i | X9I | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 3rnn | RNN | Glutamate receptor 2 | / | 0.440 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.440 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.440 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.440 | |
| 4g6o | E28 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.440 | |
| 4in4 | 4ID | Kelch-like ECH-associated protein 1 | / | 0.440 | |
| 4k4p | 3TL | Gag-Pol polyprotein | / | 0.440 | |
| 4kgm | ATP | Uncharacterized protein | / | 0.440 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.440 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.440 | |
| 5a3b | APR | SIR2 family protein | / | 0.440 | |
| 5bsg | NAP | Pyrroline-5-carboxylate reductase | / | 0.440 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.440 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.440 |