sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2vie | VG0 | Beta-secretase 1 | 3.4.23.46 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2vie | VG0 | Beta-secretase 1 | 3.4.23.46 | 1.000 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.657 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.645 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.615 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.606 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.600 | |
| 2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 | 0.588 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.587 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.565 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.554 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.553 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.549 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.548 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.548 | |
| 2viz | VG4 | Beta-secretase 1 | 3.4.23.46 | 0.546 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.544 | |
| 2f3e | AXQ | Beta-secretase 1 | 3.4.23.46 | 0.540 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.538 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.532 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.531 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.530 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.527 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.526 | |
| 2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 | 0.522 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.520 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.518 | |
| 2vj7 | VG6 | Beta-secretase 1 | 3.4.23.46 | 0.515 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.515 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.510 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.509 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.507 | |
| 2vj9 | VG7 | Beta-secretase 1 | 3.4.23.46 | 0.507 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.506 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.506 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.500 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.499 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.495 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.493 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.493 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.490 | |
| 1w51 | L01 | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.488 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.488 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.486 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.486 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.486 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.486 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.485 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.485 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.483 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.483 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.482 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.481 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.481 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.480 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.480 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.479 | |
| 1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.478 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.478 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.478 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.478 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.477 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.477 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.477 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.476 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.476 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.476 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.475 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.475 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.474 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.474 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.474 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.474 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.474 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.474 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.473 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.472 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.472 | |
| 1req | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.472 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.472 | |
| 4dja | FAD | (6-4) photolyase | / | 0.472 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.472 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.472 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.472 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.471 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.470 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.470 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.470 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.470 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.470 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.470 | |
| 5dp2 | NAP | CurF | / | 0.470 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.469 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.469 | |
| 2w3b | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.469 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.469 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.468 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.468 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.468 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.468 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.468 | |
| 4xr9 | NAD | CalS8 | / | 0.468 | |
| 7mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.468 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.467 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.467 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.467 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.466 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.466 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.466 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.466 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.466 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.466 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.466 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.466 | |
| 4blr | UTP | NTPase P4 | / | 0.466 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.466 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.465 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.465 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.465 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.465 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.464 | |
| 3aut | NAI | Glucose 1-dehydrogenase 4 | 1.1.1.47 | 0.464 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.464 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.464 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.463 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.463 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.463 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.463 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.463 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3eku | CY9 | Actin-5C | / | 0.463 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.463 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.463 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.463 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.463 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.463 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.463 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.462 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.462 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.462 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.462 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.462 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.462 | |
| 3gob | HXX | DdmC | / | 0.462 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.462 | |
| 4h8a | NAI | Ureidoglycolate dehydrogenase (NAD(+)) | 1.1.1.350 | 0.462 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.461 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.461 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.461 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.461 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 3ieu | GDP | GTPase Era | / | 0.461 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.461 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.460 | |
| 1mht | SAH | Modification methylase HhaI | 2.1.1.37 | 0.460 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.460 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.460 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.460 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.460 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.460 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.460 | |
| 3amf | FMN | FMN-binding protein | / | 0.460 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.460 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.460 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.460 | |
| 5bmv | VLB | Tubulin alpha-1B chain | / | 0.460 | |
| 5bmv | VLB | Tubulin beta chain | / | 0.460 | |
| 5f8f | SFG | Possible transcriptional regulatory protein | / | 0.460 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.460 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.459 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.459 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.459 | |
| 2vht | ATP | NTPase P4 | / | 0.459 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.459 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 3d8b | ADP | Fidgetin-like protein 1 | 3.6.4 | 0.459 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.459 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.459 | |
| 3jsz | UPG | Uncharacterized protein | / | 0.459 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.459 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.459 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.458 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.458 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.458 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.458 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.458 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2j08 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.458 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.458 | |
| 2zrx | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.458 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.458 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.458 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.458 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.458 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.458 | |
| 4yp5 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.458 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.457 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.457 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.457 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.457 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.457 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.457 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.457 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.457 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.457 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.457 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.457 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.456 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.456 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.456 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3a20 | FMN | FMN-binding protein | / | 0.456 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.456 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.456 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.456 | |
| 4qec | NAP | ElxO | / | 0.456 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.456 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.455 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.455 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.455 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.455 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.455 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.455 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.455 | |
| 3eks | CY9 | Actin-5C | / | 0.455 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.455 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.455 | |
| 3r5y | F42 | Uncharacterized protein | / | 0.455 | |
| 3sj7 | NDP | 3-oxoacyl-(Acyl-carrier-protein) reductase, putative | / | 0.455 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.455 | |
| 1bp6 | UMP | Thymidylate synthase | / | 0.454 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.454 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 1i0s | FMN | Ferric-chelate reductase (NAD(P)H) | / | 0.454 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.454 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.454 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.454 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.454 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.454 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.454 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.454 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.454 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.454 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.454 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.454 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.453 | |
| 1e2n | RCA | Thymidine kinase | / | 0.453 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.453 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.453 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.453 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.453 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.453 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.453 | |
| 2b36 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.453 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.453 | |
| 2gc8 | 885 | Polyprotein | / | 0.453 | |
| 2hg1 | N5O | Endoplasmin | / | 0.453 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.453 | |
| 3a6r | FMN | FMN-binding protein | / | 0.453 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.453 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.453 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.453 | |
| 3oee | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.453 | |
| 3oee | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.453 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3vy2 | FMN | FMN-binding protein | / | 0.453 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.453 | |
| 4jic | FMN | GTN Reductase | / | 0.453 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.453 | |
| 4yfy | 1YJ | VioF | / | 0.453 | |
| 5cts | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.453 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.452 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.452 | |
| 1het | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.452 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.452 | |
| 1t57 | FMN | Conserved protein | / | 0.452 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.452 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.452 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.452 | |
| 2zcj | SAH | Modification methylase HhaI | 2.1.1.37 | 0.452 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.452 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3lpg | Z78 | Beta-glucuronidase | 3.2.1.31 | 0.452 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3udj | 092 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.452 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.452 | |
| 5a3b | APR | SIR2 family protein | / | 0.452 | |
| 5jla | NAD | Putative short-chain dehydrogenase/reductase | / | 0.452 | |
| 5mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.452 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.451 | |
| 1nbo | NAD | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.451 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.451 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.451 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.451 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.451 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.451 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.451 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.451 | |
| 4tyq | AP5 | Adenylate kinase | / | 0.451 | |
| 5czy | SAM | Eukaryotic huntingtin interacting protein B | / | 0.451 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.451 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.450 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.450 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.450 | |
| 2wb2 | FAD | RE11660p | / | 0.450 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.450 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.450 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.450 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.450 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.450 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.450 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.450 | |
| 4eue | NAI | Trans-2-enoyl-CoA reductase [NADH] | / | 0.450 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.450 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.450 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.450 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.449 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 2el0 | SAH | Diphthine synthase | / | 0.449 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.449 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.449 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3a3g | DLZ | Lumazine protein | / | 0.449 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.449 | |
| 3cph | GDP | Ras-related protein SEC4 | / | 0.449 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.449 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.449 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.449 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.449 | |
| 4bls | APC | NTPase P4 | / | 0.449 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.449 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.449 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.449 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.448 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.448 | |
| 1pg3 | PRX | Acetyl-coenzyme A synthetase | / | 0.448 | |
| 1ysz | NEC | Endoplasmin | / | 0.448 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.448 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.448 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.448 | |
| 2qfo | A51 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.448 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.448 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.448 | |
| 3iaa | TYD | CalG2 | / | 0.448 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.448 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.448 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.448 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.448 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.448 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.447 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.447 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.447 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.447 | |
| 2emu | SAH | Diphthine synthase | / | 0.447 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.447 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.447 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.447 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.447 | |
| 3a6q | FMN | FMN-binding protein | / | 0.447 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.447 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.447 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.447 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.447 | |
| 3nbv | ANP | Ketohexokinase | / | 0.447 | |
| 3u9e | COA | Lmo1369 protein | / | 0.447 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 4qi7 | FAD | Cellobiose dehydrogenase | / | 0.447 | |
| 4tlz | FAD | KtzI | / | 0.447 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.446 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.446 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.446 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.446 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.446 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.446 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.446 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.446 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.446 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.446 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3kt8 | LTN | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.446 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.446 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.446 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.446 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.446 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.445 | |
| 2owf | SAH | Diphthine synthase | / | 0.445 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.445 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.445 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.445 | |
| 3r96 | ACO | MccE protein | / | 0.445 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.445 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.445 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.445 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.445 | |
| 4ddy | DN6 | Beta-lactamase | / | 0.445 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.445 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.445 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.445 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4rqu | NAD | Alcohol dehydrogenase class-P | / | 0.445 | |
| 5js6 | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.445 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.444 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.444 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.444 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.444 | |
| 1jmh | UMP | Thymidylate synthase | / | 0.444 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.444 | |
| 2ejz | SAH | Diphthine synthase | / | 0.444 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.444 | |
| 2wd9 | IBP | Acyl-coenzyme A synthetase ACSM2A, mitochondrial | 6.2.1.2 | 0.444 | |
| 2yy5 | WSA | Tryptophan--tRNA ligase | 6.1.1.2 | 0.444 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.444 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.444 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 3wds | NAD | NADH-dependent quinuclidinone reductase | / | 0.444 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.444 | |
| 4eki | 0QK | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.444 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.444 | |
| 4y0k | NAP | AntE | / | 0.444 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.444 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.444 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.443 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1w48 | APC | NTPase P4 | / | 0.443 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.443 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.443 | |
| 2hjr | APR | Malate dehydrogenase, adjacent gene encodes predicted lactate dehydrogenase | / | 0.443 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.443 | |
| 2vhz | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.443 | |
| 2z1q | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.443 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.443 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.443 | |
| 3rk1 | ATP | N-type ATP pyrophosphatase superfamily | / | 0.443 | |
| 3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.443 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.443 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.443 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.443 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.442 | |
| 1g5q | ASP_SER_TYR_THR_CYS | Epidermin decarboxylase | 4.1.1 | 0.442 | |
| 1ipe | NDP | Tropinone reductase 2 | 1.1.1.236 | 0.442 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.442 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.442 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.442 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.442 | |
| 2e83 | FMN | FMN-binding protein | / | 0.442 | |
| 2g2z | COZ | Malonyl CoA-acyl carrier protein transacylase | 2.3.1.39 | 0.442 | |
| 2jcv | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
| 2p20 | PRX | Acetyl-coenzyme A synthetase | / | 0.442 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.442 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.442 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.442 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.442 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3eld | SFG | Methyltransferase | / | 0.442 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.442 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.442 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.441 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.441 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.441 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.441 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.441 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.441 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.441 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 2xy3 | DUP | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.441 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.441 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.441 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3g6z | A7T | Renin | 3.4.23.15 | 0.441 | |
| 3gu8 | 3GU | Death-associated protein kinase 1 | 2.7.11.1 | 0.441 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.441 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.441 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.441 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.441 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.441 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4d0l | GSP | Ras-related protein Rab-11A | / | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.441 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.441 | |
| 4xcz | FON | Qdtf | / | 0.441 | |
| 4z38 | FMN | MlnA | / | 0.441 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.440 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.440 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1xgj | HTC | Beta-lactamase | 3.5.2.6 | 0.440 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.440 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.440 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.440 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.440 | |
| 3bnk | FMN | Flavoredoxin | / | 0.440 | |
| 3bwc | SAM | Spermidine synthase, putative | / | 0.440 | |
| 3d2p | COA | Amino-acid acetyltransferase | / | 0.440 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 3so9 | 017 | Pol protein | / | 0.440 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.440 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.440 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.440 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.440 |