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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
4dlj6RGMitogen-activated protein kinase 14

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
4dlj6RGMitogen-activated protein kinase 14/1.000
3fmn530Mitogen-activated protein kinase 14/0.598
3l8sBFFMitogen-activated protein kinase 14/0.581
1ouy094Mitogen-activated protein kinase 14/0.575
3fmlFMLMitogen-activated protein kinase 14/0.569
3flsFLSMitogen-activated protein kinase 14/0.565
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.560
2ghmLICMitogen-activated protein kinase 14/0.559
3flq891Mitogen-activated protein kinase 14/0.556
4eh70OOMitogen-activated protein kinase 14/0.556
3o8tBMUMitogen-activated protein kinase 14/0.554
1zyjBI5Mitogen-activated protein kinase 14/0.552
1ove358Mitogen-activated protein kinase 14/0.549
4eh60ONMitogen-activated protein kinase 14/0.547
3gc9B45Mitogen-activated protein kinase 112.7.11.240.545
4eh50OMMitogen-activated protein kinase 14/0.539
3oc1BMUMitogen-activated protein kinase 14/0.538
3fsfFSSMitogen-activated protein kinase 14/0.536
3lfcZ86Mitogen-activated protein kinase 14/0.534
3uvp048Mitogen-activated protein kinase 14/0.531
1ouk084Mitogen-activated protein kinase 14/0.529
3s4qNK0Mitogen-activated protein kinase 14/0.528
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.527
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.527
3gc7B45Mitogen-activated protein kinase 14/0.524
4f640S8Fibroblast growth factor receptor 1/0.524
3kf7L9GMitogen-activated protein kinase 14/0.521
4fuxE75Mitogen-activated protein kinase 12.7.11.240.520
2ittAEEEpidermal growth factor receptor2.7.10.10.519
4gk2L66Ephrin type-A receptor 32.7.10.10.518
3vjoANPEpidermal growth factor receptor2.7.10.10.514
4f630S7Fibroblast growth factor receptor 1/0.513
4eym0RXMitogen-activated protein kinase 132.7.11.240.512
4l49CAMCamphor 5-monooxygenase1.14.15.10.511
2ewaSB2Mitogen-activated protein kinase 14/0.509
3gfeP37Mitogen-activated protein kinase 14/0.509
3iw6PP0Mitogen-activated protein kinase 14/0.509
3mvl38PMitogen-activated protein kinase 14/0.509
1yw2PGJMitogen-activated protein kinase 14/0.508
2zazGK1Mitogen-activated protein kinase 14/0.507
3hv3R49Mitogen-activated protein kinase 14/0.507
2zb0GK3Mitogen-activated protein kinase 14/0.506
4hyu1BKMitogen-activated protein kinase 82.7.11.240.506
2eb3ANPEpidermal growth factor receptor2.7.10.10.505
1ywrLI9Mitogen-activated protein kinase 14/0.504
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.504
4qnaX11Serine/threonine-protein kinase 242.7.11.10.504
1bl7SB4Mitogen-activated protein kinase 14/0.503
2vd5BI8Myotonin-protein kinase2.7.11.10.503
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.503
2itzIREEpidermal growth factor receptor2.7.10.10.502
3itzP66Mitogen-activated protein kinase 14/0.502
3obgSB2Mitogen-activated protein kinase 14/0.502
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.502
4nka2K7Fibroblast growth factor receptor 1/0.502
1bl6SB6Mitogen-activated protein kinase 14/0.501
2i0ePDSProtein kinase C beta type2.7.11.130.501
3l8xN4DMitogen-activated protein kinase 14/0.501
3uvqFS8Mitogen-activated protein kinase 14/0.500
4nks2M2Fibroblast growth factor receptor 1/0.500
3iw5DF3Mitogen-activated protein kinase 14/0.499
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.498
3uibSB2Putative mitogen-activated protein kinase/0.498
4joa3DKALK tyrosine kinase receptor2.7.10.10.497
3uzcT4EAdenosine receptor A2a/0.497
3dt1P40Mitogen-activated protein kinase 14/0.496
3iphG11Mitogen-activated protein kinase 14/0.496
1m7qDQOMitogen-activated protein kinase 14/0.495
3hllI45Mitogen-activated protein kinase 14/0.495
3h0sB38Acetyl-CoA carboxylase/0.494
1k6cMK1Gag-Pol polyprotein3.4.23.160.493
1k6pXN3Gag-Pol polyprotein3.4.23.160.493
2j7t274Serine/threonine-protein kinase 102.7.11.10.493
4r20AERCytochrome P450 family 17 polypeptide 2/0.493
1phgMYTCamphor 5-monooxygenase1.14.15.10.492
2b5vNAPGlucose 1-dehydrogenase/0.492
3bx5304Mitogen-activated protein kinase 14/0.492
3hp552PMitogen-activated protein kinase 14/0.492
3ha85JZMitogen-activated protein kinase 14/0.491
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.491
1og5SWFCytochrome P450 2C9/0.490
1t88CAMCamphor 5-monooxygenase1.14.15.10.490
2yixYIXMitogen-activated protein kinase 14/0.490
1iwjCAMCamphor 5-monooxygenase1.14.15.10.489
4kbk1QGCasein kinase I isoform delta2.7.11.10.489
1k6tXN1Gag-Pol polyprotein3.4.23.160.488
2gfsPQBMitogen-activated protein kinase 14/0.488
3flwFLWMitogen-activated protein kinase 14/0.488
1w2xRCPAcetyl-CoA carboxylase/0.487
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.487
4l4cCAMCamphor 5-monooxygenase1.14.15.10.487
3flzFLZMitogen-activated protein kinase 14/0.486
3gubGUBDeath-associated protein kinase 12.7.11.10.486
3tucFPWTyrosine-protein kinase SYK2.7.10.20.486
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.486
1fpqSAMIsoliquiritigenin 2'-O-methyltransferase/0.485
4anqVGHALK tyrosine kinase receptor2.7.10.10.485
4c9pCAMCytochrome P450/0.485
4i231C9Epidermal growth factor receptor2.7.10.10.485
2fgiPD1Fibroblast growth factor receptor 1/0.484
3mpaSB2Mitogen-activated protein kinase 14/0.484
3t113T1Gag-Pol polyprotein3.4.23.160.484
4ia3BIVVitamin D3 receptor A/0.484
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.484
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.483
2of4979Tyrosine-protein kinase Lck2.7.10.20.483
3ezrEZRCyclin-dependent kinase 22.7.11.220.483
3igoANPCalmodulin-domain protein kinase 1, putative/0.483
2x6dX6DAurora kinase A2.7.11.10.482
3w33W19Epidermal growth factor receptor2.7.10.10.482
1j39UPGDNA beta-glucosyltransferase/0.481
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.481
2qo5CHDFatty acid-binding protein 10-A, liver basic/0.481
4dpwAGSMevalonate diphosphate decarboxylase/0.481
4neuQ1AReceptor-interacting serine/threonine-protein kinase 12.7.11.10.481
4wkqIREEpidermal growth factor receptor2.7.10.10.481
1u54ACPActivated CDC42 kinase 1/0.480
2qblCAMCamphor 5-monooxygenase1.14.15.10.480
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
3l63CAMCamphor 5-monooxygenase1.14.15.10.480
3roc29AMitogen-activated protein kinase 14/0.480
4izy1J2Mitogen-activated protein kinase 82.7.11.240.480
4l4aCAMCamphor 5-monooxygenase1.14.15.10.480
3reyXACAdenosine receptor A2a/0.480
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.479
3nww3NWMitogen-activated protein kinase 14/0.479
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.479
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.479
5dr9SKEAurora kinase A2.7.11.10.479
5eypLOCTubulin beta chain/0.479
2cig1DGDihydrofolate reductase1.5.1.30.478
2pvrANPCasein kinase II subunit alpha2.7.11.10.478
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.478
2rg6287Mitogen-activated protein kinase 14/0.478
2xp2VGHALK tyrosine kinase receptor2.7.10.10.478
3cppCAMCamphor 5-monooxygenase1.14.15.10.478
3flyFLYMitogen-activated protein kinase 14/0.478
3fmjFMJMitogen-activated protein kinase 14/0.478
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.478
3zewSTUEphrin type-B receptor 42.7.10.10.478
4ctaATPCinA-like protein/0.478
4jrnANPRhoptry kinase family protein/0.478
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.478
1gebCAMCamphor 5-monooxygenase1.14.15.10.477
3gcq1BUMitogen-activated protein kinase 14/0.477
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.477
4ia7BIVVitamin D3 receptor A/0.477
4o0sADNAurora kinase A2.7.11.10.477
2cppCAMCamphor 5-monooxygenase1.14.15.10.476
2ghlLIBMitogen-activated protein kinase 14/0.476
2rkfAB1Pol protein/0.476
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.476
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.476
4hys1BJMitogen-activated protein kinase 82.7.11.240.476
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.476
4z34ON7Lysophosphatidic acid receptor 1/0.476
1jvsNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.475
1nooCAHCamphor 5-monooxygenase1.14.15.10.475
2qd7065Gag-Pol polyprotein3.4.23.160.475
3fc152PMitogen-activated protein kinase 14/0.475
3fzpAGSProtein-tyrosine kinase 2-beta2.7.10.20.475
3lfa1N1Mitogen-activated protein kinase 14/0.475
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
4nfn2KCTau-tubulin kinase 12.7.11.10.475
5e8xSTUTGF-beta receptor type-12.7.11.300.475
1agwSU2Fibroblast growth factor receptor 1/0.474
1t87CAMCamphor 5-monooxygenase1.14.15.10.474
1tvoFRZMitogen-activated protein kinase 12.7.11.240.474
2a1mCAMCamphor 5-monooxygenase1.14.15.10.474
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.474
3u8w09JMitogen-activated protein kinase 14/0.474
4cp4CAMCamphor 5-monooxygenase1.14.15.10.474
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.474
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.474
1w84L12Mitogen-activated protein kinase 14/0.473
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.473
2hcdBIVVitamin D3 receptor A/0.473
2oz6CMPCyclic AMP receptor-like protein/0.473
3d7tSTUTyrosine-protein kinase CSK/0.473
3fwjCAMCamphor 5-monooxygenase1.14.15.10.473
3gstGPRGlutathione S-transferase Mu 12.5.1.180.473
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.473
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4jlj1NMDeoxycytidine kinase2.7.1.740.473
1t86CAMCamphor 5-monooxygenase1.14.15.10.472
2balPQAMitogen-activated protein kinase 14/0.472
2itvANPEpidermal growth factor receptor2.7.10.10.472
2itwITQEpidermal growth factor receptor2.7.10.10.472
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.472
4e730NRMitogen-activated protein kinase 82.7.11.240.472
4h9753SDihydrofolate reductase1.5.1.30.472
4hvh19RTyrosine-protein kinase JAK32.7.10.20.472
4rupH97Vitamin D3 receptor A/0.472
2gstGPSGlutathione S-transferase Mu 12.5.1.180.471
3fln3FNMitogen-activated protein kinase 14/0.471
3icsADPCoenzyme A disulfide reductase/0.471
3mdvCL6Cholesterol 24-hydroxylase/0.471
4aacAAVMitogen-activated protein kinase 14/0.471
4dt8ADNAPH(2'')-Id/0.471
4h9614QDihydrofolate reductase1.5.1.30.471
4jrvKJVEpidermal growth factor receptor2.7.10.10.471
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.471
4nb6444Nuclear receptor ROR-gamma/0.471
5ce3ADPProtein kinase YopO/0.471
6gswGPSGlutathione S-transferase Mu 12.5.1.180.471
1oecAA2Fibroblast growth factor receptor 2/0.470
2a1nCAMCamphor 5-monooxygenase1.14.15.10.470
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.470
2jn3JN3Fatty acid-binding protein, liver/0.470
2rg5279Mitogen-activated protein kinase 14/0.470
2vwpNDPGlucose 1-dehydrogenase/0.470
3frqERYErythromycin resistance repressor protein/0.470
3lxiCAMCytochrome P450/0.470
3nj0PYVAbscisic acid receptor PYL2/0.470
3w2o03PEpidermal growth factor receptor2.7.10.10.470
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.470
4ewqMWLMitogen-activated protein kinase 14/0.470
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.470
4lxhC1EAlpha/beta hydrolase fold/0.470
1ykr628Cyclin-dependent kinase 22.7.11.220.469
2itnANPEpidermal growth factor receptor2.7.10.10.469
3iqfE4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.469
4dk50KOPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.469
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.469
2bujSTUSerine/threonine-protein kinase 16/0.468
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.468
3fkoFKOMitogen-activated protein kinase 14/0.468
3fl4FL4Mitogen-activated protein kinase 14/0.468
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
4btkDTQTau-tubulin kinase 12.7.11.10.468
4dtaADNAPH(2'')-Id/0.468
4ek1CAMCamphor 5-monooxygenase1.14.15.10.468
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.467
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.467
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.467
2vn0TDZCytochrome P450 2C8/0.467
2zbaZBATrichothecene 3-O-acetyltransferase/0.467
3b2tM33Fibroblast growth factor receptor 2/0.467
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.467
3fmh533Mitogen-activated protein kinase 14/0.467
3jw5TOPDihydrofolate reductase/0.467
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.467
4cd0AWJALK tyrosine kinase receptor2.7.10.10.467
4l445FIRibosomal protein S6 kinase beta-12.7.11.10.467
1dz6CAMCamphor 5-monooxygenase1.14.15.10.466
2a1oCAMCamphor 5-monooxygenase1.14.15.10.466
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.466
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.466
3fmkFMKMitogen-activated protein kinase 14/0.466
3ictADPCoenzyme A disulfide reductase/0.466
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.466
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.466
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.466
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.466
4xiwAZMCarbonic anhydrase, alpha type/0.466
1dhiMTXDihydrofolate reductase1.5.1.30.465
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.465
1v9aSAHUncharacterized protein/0.465
2hog710Serine/threonine-protein kinase Chk12.7.11.10.465
2j0k4STFocal adhesion kinase 12.7.10.20.465
2of2547Tyrosine-protein kinase Lck2.7.10.20.465
2ywvADPPhosphoribosylaminoimidazole-succinocarboxamide synthase/0.465
3cisATPUniversal stress protein Rv2623/0.465
3lctADPALK tyrosine kinase receptor2.7.10.10.465
3q5lKX2Heat shock protein 83-1/0.465
3qly55VUncharacterized protein/0.465
3qp0NI8Gag-Pol polyprotein3.4.23.160.465
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.465
1iwiCAMCamphor 5-monooxygenase1.14.15.10.464
2acxANPG protein-coupled receptor kinase 62.7.11.160.464
2etm7PYFocal adhesion kinase 12.7.10.20.464
2vwu7X1Ephrin type-B receptor 42.7.10.10.464
3bheBZNGag-Pol polyprotein3.4.23.160.464
4gyiADPUncharacterized protein/0.464
4l4dCAMCamphor 5-monooxygenase1.14.15.10.464
4ruoBIVVitamin D3 receptor A/0.464
5cp4CAMCamphor 5-monooxygenase1.14.15.10.464
1dssNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.463
1k6vXN2Gag-Pol polyprotein3.4.23.160.463
1v1k3FPCyclin-dependent kinase 22.7.11.220.463
1wbpADPSRSF protein kinase 12.7.11.10.463
2hb7O1CVitamin D3 receptor/0.463
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.463
2uzhIPE2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.463
3csdEMOPutative ketoacyl reductase1.3.10.463
3fi3JK2Mitogen-activated protein kinase 102.7.11.240.463
3pxkPXKFocal adhesion kinase 12.7.10.20.463
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.463
4becATPType I restriction enzyme EcoR124II R protein3.1.21.30.463
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.463
4g3rCAMCamphor 5-monooxygenase1.14.15.10.463
4ia1BIVVitamin D3 receptor A/0.463
4ienCOAPutative acyl-CoA hydrolase/0.463
4l4fCAMCamphor 5-monooxygenase1.14.15.10.463
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.463
1fm4DXCMajor pollen allergen Bet v 1-L/0.462
1sh9RITGag-Pol polyprotein3.4.23.160.462
1xl2189Gag-Pol polyprotein3.4.23.160.462
1zgaHMKIsoflavone 4'-O-methyltransferase/0.462
2b9wFADPutative aminooxidase/0.462
2rhgIGPTryptophan synthase alpha chain/0.462
2rhrEMOPutative ketoacyl reductase1.3.10.462
2z97CAMCamphor 5-monooxygenase1.14.15.10.462
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.462
3clbNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.462
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.462
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.462
3vrwYS5Vitamin D3 receptor/0.462
4bcqTJFCyclin-dependent kinase 22.7.11.220.462
4cdmFADDeoxyribodipyrimidine photolyase/0.462
4fob0USALK tyrosine kinase receptor2.7.10.10.462
4l4bCAMCamphor 5-monooxygenase1.14.15.10.462
4qmlANPSerine/threonine-protein kinase 242.7.11.10.462
1enyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
2a0cCK9Cyclin-dependent kinase 22.7.11.220.461
2cciATPCyclin-dependent kinase 22.7.11.220.461
2fleAIProtease/0.461
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.461
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.461
3zuxTCHTransporter/0.461
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.461
4gk4L90Ephrin type-A receptor 32.7.10.10.461
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.461
4kgmATPUncharacterized protein/0.461
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.461
5ai5BSUBifunctional epoxide hydrolase 23.1.3.760.461
5cu6ATPCasein kinase II subunit alpha2.7.11.10.461
1svlADPLarge T antigen3.6.40.460
2itqITQEpidermal growth factor receptor2.7.10.10.460
2qboCAMCamphor 5-monooxygenase1.14.15.10.460
3bqdDAYGlucocorticoid receptor/0.460
3cseN22Uncharacterized protein/0.460
3d1xROCGag-Pol polyprotein3.4.23.160.460
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
3vt8YI3Vitamin D3 receptor/0.460
4c2uANPDNA helicase/0.460
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.460
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.460
4j97ACPFibroblast growth factor receptor 2/0.460
4kigENOPhenylpyruvate C(3)-methyltransferase2.1.1.2810.460
4kiq1RAMitogen-activated protein kinase 14/0.460
1enzNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.459
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.459
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.459
2c7xNRBCytochrome P450 monooxygenase PikC/0.459
2vx07X7Ephrin type-B receptor 42.7.10.10.459
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.459
3aidARQGag-Pol polyprotein3.4.23.160.459
3gwfFADCyclohexanone monooxygenase/0.459
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
3n0tOPYDipeptidyl peptidase 23.4.14.20.459
3r6pA8SAbscisic acid receptor PYL10/0.459
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.459
4elg52JDihydrofolate reductase/0.459
4gk3L87Ephrin type-A receptor 32.7.10.10.459
4gub0Y4Casein kinase II subunit alpha2.7.11.10.459
4l8u9AZSerum albumin/0.459
4uyf73BBromodomain-containing protein 2/0.459
5e8wSTUTGF-beta receptor type-12.7.11.300.459
1ia2TQ4Dihydrofolate reductase1.5.1.30.458
1owmFADDeoxyribodipyrimidine photo-lyase4.1.99.30.458
1xkkFMMEpidermal growth factor receptor2.7.10.10.458
2g2fAGSTyrosine-protein kinase ABL12.7.10.20.458
2jedLG8Protein kinase C theta type2.7.11.130.458
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2yeiXQIHeat shock protein HSP 90-alpha/0.458
3cv9VDXVitamin D3 dihydroxylase/0.458
3fwfCAMCamphor 5-monooxygenase1.14.15.10.458
3iqzH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.458
3jwcEKBDihydrofolate reductase/0.458
3k6l2BBPeptide deformylase3.5.1.880.458
3lovFADProtoporphyrinogen oxidase/0.458
3nwq2NCGag-Pol polyprotein3.4.23.160.458
3os33OSDual specificity mitogen-activated protein kinase kinase 12.7.12.20.458
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.458
3wrjCAMCamphor 5-monooxygenase1.14.15.10.458
3zsh469Mitogen-activated protein kinase 14/0.458
3zuyTCHTransporter/0.458
4ansVGHALK tyrosine kinase receptor2.7.10.10.458
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.458
4loqSB4Mitogen-activated protein kinase 14/0.458
4tuvCPZCytochrome P450 1191.140.458
5eccNAPDehydrofolate reductase type I/0.458
1me8RVPInosine-5'-monophosphate dehydrogenase/0.457
1pjkANPCasein kinase II subunit alpha2.7.11.10.457
2aidTHKGag-Pol polyprotein3.4.23.160.457
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2drcMTXDihydrofolate reductase1.5.1.30.457
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.457
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.457
3etgGWDGlutamate dehydrogenase 1, mitochondrial1.4.1.30.457
3gggNADPrephenate dehydrogenase/0.457
3njoP2MAbscisic acid receptor PYR1/0.457
3nwxKVSGag-Pol polyprotein3.4.23.160.457
3oc4FADOxidoreductase, pyridine nucleotide-disulfide family/0.457
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.457
3u4uLNHCasein kinase II subunit alpha2.7.11.10.457
4nj32KDCyclin-dependent kinase 22.7.11.220.457
4pl3ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.457
4ryvZEAProtein LlR18A/0.457
9hvp0E9Gag-Pol polyprotein/0.457
1aylATPPhosphoenolpyruvate carboxykinase (ATP)/0.456
1ddsMTXDihydrofolate reductase1.5.1.30.456
1lhvNOGSex hormone-binding globulin/0.456
1o76CAMCamphor 5-monooxygenase1.14.15.10.456
1tl1H18Gag-Pol polyprotein2.7.7.490.456
2itxANPEpidermal growth factor receptor2.7.10.10.456
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.456
2q9fC3SCholesterol 24-hydroxylase/0.456
2qo9ANPEphrin type-A receptor 32.7.10.10.456
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.456
3fklFKLMitogen-activated protein kinase 14/0.456
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.456
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.456
3s56ROCProtease/0.456
3ucb017Gag-Pol polyprotein/0.456
4fki09KCyclin-dependent kinase 22.7.11.220.456
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.456
4jq7KJQEpidermal growth factor receptor2.7.10.10.456
4kkyCAMCamphor 5-monooxygenase1.14.15.10.456
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.456
5dr6SKEAurora kinase A2.7.11.10.456
1idb0DOGag-Pol polyprotein/0.455
1knuYPAPeroxisome proliferator-activated receptor gamma/0.455
1xefATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.455
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.455
2f3kRO1Protease/0.455
2hk51BMTyrosine-protein kinase HCK2.7.10.20.455
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.455
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.455
2z4y252Geranylgeranyl pyrophosphate synthase/0.455
3anlNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.455
3cgdNADCoenzyme A disulfide reductase/0.455
3d7kD7KBenzaldehyde lyase/0.455
3koo24DBifunctional epoxide hydrolase 23.3.2.100.455
3swrSFGDNA (cytosine-5)-methyltransferase 12.1.1.370.455
3vjnANPEpidermal growth factor receptor2.7.10.10.455
4dce0JFALK tyrosine kinase receptor2.7.10.10.455
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.455
4h9506UDihydrofolate reductase1.5.1.30.455
4ubsDIFPentalenic acid synthase1.14.15.110.455
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.455
5dhhDGWNociceptin receptor/0.455
1bygSTUTyrosine-protein kinase CSK/0.454
1dz8CAMCamphor 5-monooxygenase1.14.15.10.454
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.454
1jioDEB6-deoxyerythronolide B hydroxylase/0.454
1npa3NHGag-Pol polyprotein3.4.23.160.454
1npwLGZGag-Pol polyprotein3.4.23.160.454
1uyuCAMCamphor 5-monooxygenase1.14.15.10.454
1zarADPRIO-type serine/threonine-protein kinase Rio22.7.11.10.454
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
2azzTCHPhospholipase A2, major isoenzyme3.1.1.40.454
2hamC33Vitamin D3 receptor/0.454
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
2py3ACPFibroblast growth factor receptor 2/0.454
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.454
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.454
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.454
3i0rRT3Gag-Pol polyprotein2.7.7.490.454
3lfnA27Cyclin-dependent kinase 22.7.11.220.454
3nmhPYVAbscisic acid receptor PYL2/0.454
3qlrNDPDihydrofolate reductase1.5.1.30.454
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.454
3uowXMPGMP synthase [glutamine-hydrolyzing]/0.454
3vtbTKAVitamin D3 receptor/0.454
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.454
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.454
4asyN5YGlucose-1-phosphate thymidylyltransferase/0.454
4c62XWWTyrosine-protein kinase JAK2/0.454
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.454
4dscA8SAbscisic acid receptor PYL3/0.454
4enhFVXCholesterol 24-hydroxylase/0.454
4gu94GUFocal adhesion kinase 12.7.10.20.454
4ma628EAra h 8 allergen/0.454
4xe606UDihydrofolate reductase1.5.1.30.454
4ylhYE1(3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase/0.454
1draMTXDihydrofolate reductase1.5.1.30.453
1dz4CAMCamphor 5-monooxygenase1.14.15.10.453
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
1hwr216Gag-Pol polyprotein3.4.23.160.453
1i8tFADUDP-galactopyranose mutase5.4.99.90.453
1ie8KH1Vitamin D3 receptor/0.453
1l2jETCEstrogen receptor beta/0.453
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.453
1rbmKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.453
1rdt570Peroxisome proliferator-activated receptor gamma/0.453
1vyzN5BCyclin-dependent kinase 22.7.11.220.453
1yrdCAMCamphor 5-monooxygenase1.14.15.10.453
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.453
1zzlTZYMitogen-activated protein kinase 14/0.453
2fziDH3Dihydrofolate reductase1.5.1.30.453
2idw017Protease/0.453
2idzZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2izuP01Casein kinase I isoform gamma-32.7.11.10.453
2pywADPMethylthioribose kinase2.7.1.1000.453
2y3rTRKTamL/0.453
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.453
3fi4FI4Mitogen-activated protein kinase 14/0.453
3qlwN22Dihydrofolate reductase1.5.1.30.453
3w9rA8SAbscisic acid receptor PYL9/0.453
3wd7COAAcridone synthase/0.453
4bcmT7ZCyclin-dependent kinase 22.7.11.220.453
1esvLARActin, alpha skeletal muscle/0.452
1ida0POGag-Pol polyprotein3.4.23.470.452
1oc1ASVIsopenicillin N synthase1.21.3.10.452
1phePIYCamphor 5-monooxygenase1.14.15.10.452
2c475IDCasein kinase I isoform gamma-2/0.452
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.452
2q59240Peroxisome proliferator-activated receptor gamma/0.452
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.452
2rkvZBATrichothecene 3-O-acetyltransferase/0.452
2zaxCAMCamphor 5-monooxygenase1.14.15.10.452
3d4pNADL-lactate dehydrogenase 11.1.1.270.452
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.452
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.452
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.452
3ua506XCytochrome P450 2B61.14.130.452
3w8wFADPutative FAD-dependent oxygenase EncM/0.452
3wrhCAMCamphor 5-monooxygenase1.14.15.10.452
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.452
4a6bQG8Gag-Pol polyprotein3.4.23.160.452
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.452
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.452
4azmT4BFatty acid-binding protein, epidermal/0.452
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.452
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4j5j478Gag-Pol polyprotein3.4.23.160.452
4ok1198Androgen receptor/0.452
4y8wSTRSteroid 21-hydroxylase/0.452
1bq6COAChalcone synthase 22.3.1.740.451
1dkfBMSRetinoic acid receptor alpha/0.451
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
1hvhQ82Gag-Pol polyprotein3.4.23.160.451
1ivq0PXGag-Pol polyprotein/0.451
1pdhFASp-hydroxybenzoate hydroxylase/0.451
1s19MC9Vitamin D3 receptor/0.451
1xnyBTNPropionyl-CoA carboxylase complex B subunit/0.451
1yinCM3Estrogen receptor/0.451
2d3mCOA5,7-dihydroxy-2-methylchromone synthase2.3.1.2160.451
2eauCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.451
2nnhREACytochrome P450 2C8/0.451
2pwuGUNQueuine tRNA-ribosyltransferase2.4.2.290.451
2yboSAHMethyltransferase/0.451
2zb1GK4Mitogen-activated protein kinase 14/0.451
3cz09ODPheromone-binding protein ASP1/0.451
3fknFKNMitogen-activated protein kinase 14/0.451
3gi6D78Gag-Pol polyprotein/0.451
3gwfNAPCyclohexanone monooxygenase/0.451
3qa2XNAKetohexokinase/0.451
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3r7yZ04Cyclin-dependent kinase 22.7.11.220.451
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.451
3srwQ27Dihydrofolate reductase1.5.1.30.451
4a33MYAGlycylpeptide N-tetradecanoyltransferase/0.451
4b99R4LMitogen-activated protein kinase 72.7.11.240.451
4d0l093Phosphatidylinositol 4-kinase beta2.7.1.670.451
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
4ek610KCyclin-dependent kinase 22.7.11.220.451
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.451
4itfTFYVitamin D3 receptor/0.451
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.451
5aacVGHALK tyrosine kinase receptor2.7.10.10.451
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
1rx8FOLDihydrofolate reductase1.5.1.30.450
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.450
2exlGDMEndoplasmin/0.450
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.450
2o2u738Mitogen-activated protein kinase 102.7.11.240.450
2ozuACOHistone acetyltransferase KAT6A/0.450
2r3wG3GGag-Pol polyprotein3.4.23.160.450
2vf0F89Thymidylate synthase/0.450
2wqbQQ1Angiopoietin-1 receptor2.7.10.10.450
2xh9J01Uncharacterized protein/0.450
3b2eADPATPase GET3/0.450
3fmmXI2Mitogen-activated protein kinase 14/0.450
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.450
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.450
3pcfFHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.450
3s00Z60Cyclin-dependent kinase 22.7.11.220.450
3tz3B36Acetyl-CoA carboxylase/0.450
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.450
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4bebATPType I restriction enzyme EcoR124II R protein3.1.21.30.450
4cd2FOLDihydrofolate reductase1.5.1.30.450
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
4iwyADPRibosomal protein S6--L-glutamate ligase/0.450
4lopSB4Mitogen-activated protein kinase 14/0.450
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.450
1ebk0Q4Gag-Pol polyprotein3.4.23.160.449
1eioGCHGastrotropin/0.449
1fvt106Cyclin-dependent kinase 22.7.11.220.449
1u5rATPSerine/threonine-protein kinase TAO22.7.11.10.449
1wvxBD4Death-associated protein kinase 12.7.11.10.449
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.449
2uw7GVPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2vwy7X5Ephrin type-B receptor 42.7.10.10.449
2ykbYKBHeat shock protein HSP 90-alpha/0.449
2zawCAMCamphor 5-monooxygenase1.14.15.10.449
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.449
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.449
3at4CCKCasein kinase II subunit alpha2.7.11.10.449
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.449
3drcMTXDihydrofolate reductase1.5.1.30.449
3eek53SUncharacterized protein/0.449
3el8PD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.449
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.449
3iqeH4MF420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.449
3p5kP5KMitogen-activated protein kinase 14/0.449
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.449
4h0xNADIota toxin component Ia/0.449
4ia2BIVVitamin D3 receptor A/0.449
4iui1GQEstrogen receptor/0.449
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.449
4qysPLRTryptophan synthase beta chain 24.2.1.200.449
4zcaADPKinesin-like protein KIF11/0.449
4zolACPTubulin tyrosine ligase/0.449
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
1w1rZEACytokinin dehydrogenase 11.5.99.120.448
1xddAAYIntegrin alpha-L/0.448
2a4zBYMPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.448
2e0aANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.448
2hasC3OVitamin D3 receptor/0.448
2p4yC03Peroxisome proliferator-activated receptor gamma/0.448
2vynNADGlyceraldehyde-3-phosphate dehydrogenase A/0.448
2xauADPPre-mRNA-splicing factor ATP-dependent RNA helicase PRP433.6.4.130.448
3dxjNE6DNA-directed RNA polymerase subunit beta/0.448
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.448
3h9f92MDual specificity protein kinase TTK2.7.12.10.448
3hub469Mitogen-activated protein kinase 14/0.448
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
3ixp834Ecdysone receptor/0.448
3t8oATPRhodopsin kinase/0.448
4ly91YYGlucokinase regulatory protein/0.448
5a9sNAPPutative dehydrogenase/0.448
1c6x3INProtease/0.447
1dhjMTXDihydrofolate reductase1.5.1.30.447
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1eupASD6-deoxyerythronolide B hydroxylase/0.447
1hpoUNIGag-Pol polyprotein3.4.23.160.447
1i58ACPChemotaxis protein CheA2.7.13.30.447
1me7MOAInosine-5'-monophosphate dehydrogenase/0.447
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.447
1qcjAPTAntiviral protein I3.2.2.220.447
1rrmAPRLactaldehyde reductase1.1.1.770.447
1uumAFIDihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.447
2e2b406Tyrosine-protein kinase ABL12.7.10.20.447
2i40BLZCyclin-dependent kinase 22.7.11.220.447
2ituITQEpidermal growth factor receptor2.7.10.10.447
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.447
2w1fL0FAurora kinase A2.7.11.10.447
2x7f824TRAF2 and NCK-interacting protein kinase2.7.11.10.447
3bxsDRSGag-Pol polyprotein3.4.23.160.447
3em6017Gag-Pol polyprotein3.4.23.160.447
3kddJZQGag-Pol polyprotein3.4.23.160.447
3och2MXDihydrofolate reductase1.5.1.30.447
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.447
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.447
4ic7ANPMitogen-activated protein kinase 72.7.11.240.447
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.447
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.447
5cccDDFDihydrofolate reductase1.5.1.30.447
6upjNIUGag-Pol polyprotein/0.447
1al8DHPPeroxisomal (S)-2-hydroxy-acid oxidase1.1.3.150.446
1drbMTXDihydrofolate reductase1.5.1.30.446
1eh4IC1Casein kinase I homolog 12.7.11.10.446
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1ictT44Transthyretin/0.446
1m75CAAHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1mawATPTryptophan--tRNA ligase6.1.1.20.446
1rc4DDFDihydrofolate reductase1.5.1.30.446
1s0zEB1Vitamin D3 receptor/0.446
1tezFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
2bakAQZMitogen-activated protein kinase 14/0.446
2feuCAMCamphor 5-monooxygenase1.14.15.10.446
2fwyH64Heat shock protein HSP 90-alpha/0.446
2pmdGNPTranslation initiation factor 2 subunit gamma/0.446
2pwlACPFibroblast growth factor receptor 2/0.446
2vthLZ2Cyclin-dependent kinase 22.7.11.220.446
2ykcYKCHeat shock protein HSP 90-alpha/0.446
3bv2P38Mitogen-activated protein kinase 14/0.446
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.446
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3mg3ECHOrange carotenoid-binding protein/0.446
3q5iANPProtein kinase, putative/0.446
3rm618ZCyclin-dependent kinase 22.7.11.220.446
3ufnROCGag-Pol polyprotein/0.446
3umvFADDeoxyribodipyrimidine photo-lyase4.1.99.30.446
3upjU03Gag-Pol polyprotein/0.446
3v9v21LPeroxisome proliferator-activated receptor gamma/0.446
3wrmCAMCamphor 5-monooxygenase1.14.15.10.446
4a6cQG9Gag-Pol polyprotein3.4.23.160.446
4a9mP9MBromodomain-containing protein 2/0.446
4a9yAQZMitogen-activated protein kinase 14/0.446
4aa5NQBMitogen-activated protein kinase 14/0.446
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.446
4c9oCAMCytochrome P450/0.446
4g1z0VPVitamin D3 receptor A/0.446
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.446
4jlk1NODeoxycytidine kinase2.7.1.740.446
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.446
5bn4ANPV-type ATP synthase alpha chain/0.446
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.445
1ie9VDXVitamin D3 receptor/0.445
1ke6LS2Cyclin-dependent kinase 22.7.11.220.445
1merDMQGag-Pol polyprotein3.4.23.160.445
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.445
1nvtNAPShikimate dehydrogenase (NADP(+))/0.445
1q99ANPSerine/threonine-protein kinase SKY12.7.11.10.445
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.445
1sn0T44Transthyretin/0.445
2bpy3INGag-Pol polyprotein3.4.23.160.445
2duv371Cyclin-dependent kinase 22.7.11.220.445
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.445
2fy4COACholine O-acetyltransferase2.3.1.60.445
2pvyACPFibroblast growth factor receptor 2/0.445
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.445
2w71L23Biotin carboxylase6.3.4.140.445
2y4gTIRTamL/0.445
3a4pDFQHepatocyte growth factor receptor2.7.10.10.445
3ac1KZITyrosine-protein kinase Lck2.7.10.20.445
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.445
3jskAHZThiamine thiazole synthase/0.445
3nglNAPBifunctional protein FolD/0.445
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.445
3s1dZIRCytokinin dehydrogenase 11.5.99.120.445
3ttjJBIMitogen-activated protein kinase 102.7.11.240.445
3vt3VDXVitamin D3 receptor/0.445
3w0rANPHygromycin-B 4-O-kinase2.7.1.1630.445
4aa4QC0Mitogen-activated protein kinase 14/0.445
4an92P7Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.445
4hni16WCasein kinase I isoform epsilon2.7.11.10.445
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.445
4k33ACPFibroblast growth factor receptor 32.7.10.10.445
4xumIMNPeroxisome proliferator-activated receptor gamma/0.445
5hi6MTXDihydrofolate reductase/0.445
5ii2LU2Protein polybromo-1/0.445
5k2cZMAAdenosine receptor A2a/0.445
4ej4EJ4Delta-type opioid receptor/0.445
1bmkSB5Mitogen-activated protein kinase 14/0.444
1cqp803Integrin alpha-L/0.444
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.444
1hncGDNGlutathione S-transferase Mu 22.5.1.180.444
1ia3TQ5Dihydrofolate reductase1.5.1.30.444
1ju6LYAThymidylate synthase2.1.1.450.444
1kkq471Peroxisome proliferator-activated receptor alpha/0.444
1lhwESMSex hormone-binding globulin/0.444
1re7FOLDihydrofolate reductase1.5.1.30.444
1wvySTUDeath-associated protein kinase 12.7.11.10.444
1zhzERGOxysterol-binding protein homolog 4/0.444
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.444
2izrBRKCasein kinase I isoform gamma-32.7.11.10.444
2m56CAMCamphor 5-monooxygenase1.14.15.10.444
2nniMTKCytochrome P450 2C8/0.444
2p15EZTEstrogen receptor/0.444
2x7gPVBSRSF protein kinase 22.7.11.10.444
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.444
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.444
3fy9XCFDihydrofolate reductase1.5.1.30.444
3h18PMSEsterase/lipase/0.444
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.444
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.444
3vt7VDXVitamin D3 receptor/0.444
3w0jT08Vitamin D3 receptor/0.444
3wv9FEGHmd co-occurring protein HcgE/0.444
4a5lNDPThioredoxin reductase/0.444
4b4oNDPEpimerase family protein SDR39U1/0.444
4dfrMTXDihydrofolate reductase1.5.1.30.444
4ejgNCTCytochrome P450 2A131.14.14.10.444
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.444
4h4vFADBiphenyl dioxygenase ferredoxin reductase subunit/0.444
4hbm0Y7E3 ubiquitin-protein ligase Mdm26.3.20.444
4hdbG52Gag-Pol polyprotein3.4.23.160.444
4ix6ADPUncharacterized protein/0.444
4kip1R9Mitogen-activated protein kinase 14/0.444
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.444
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.444
4nmdFDABifunctional protein PutA/0.444
4o2bLOCTubulin beta-2B chain/0.444
4xhgADPUncharacterized protein/0.444
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.444
5aaaVGHALK tyrosine kinase receptor2.7.10.10.444
1bveDMPGag-Pol polyprotein3.4.23.160.443
1hosPHPGag-Pol polyprotein/0.443
1qbu846Gag-Pol polyprotein3.4.23.160.443
1txiTX5Vitamin D3 receptor/0.443
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.443
1zmcNADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.443
2bpz3INGag-Pol polyprotein3.4.23.160.443
2btdADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.443
2gjlFMNNitronate monooxygenase1.13.12.160.443
2gqwFADFerredoxin reductase/0.443
2j0m4STFocal adhesion kinase 12.7.10.20.443
2qd5CHDFerrochelatase, mitochondrial4.99.1.10.443
2r43G3GGag-Pol polyprotein3.4.23.160.443
2r64740Cyclin-dependent kinase 22.7.11.220.443
2vrx447Aurora kinase B-A2.7.11.10.443
3hx4ANPCalmodulin-domain protein kinase 1/0.443
3jw3TOPDihydrofolate reductase/0.443
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3o9aK14Pol polyprotein/0.443
3opdHIEHeat shock protein 83/0.443
3pgqGY3Acetyl-CoA carboxylase/0.443
3qlxQLRUncharacterized protein/0.443
3qqkX02Cyclin-dependent kinase 22.7.11.220.443
3qx4X4BCyclin-dependent kinase 22.7.11.220.443
3rasNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.443
3w0iO11Vitamin D3 receptor/0.443
3zpuM8BGag-Pol polyprotein3.4.23.160.443
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.443
4ele31IDihydrofolate reductase/0.443
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.443
4fkj11KCyclin-dependent kinase 22.7.11.220.443
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.443
4l4eCAMCamphor 5-monooxygenase1.14.15.10.443
4o6mC5PUncharacterized protein/0.443
4wa9AXITyrosine-protein kinase ABL12.7.10.20.443
4z07PCGcGMP-dependent protein kinase 12.7.11.120.443
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.443
5br4NADLactaldehyde reductase1.1.1.770.443
5k2bZMAAdenosine receptor A2a/0.443
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.442
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1odw0E8Gag-Pol polyprotein3.4.23.160.442
1oz1FPHMitogen-activated protein kinase 14/0.442
1rx7FOLDihydrofolate reductase1.5.1.30.442
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.442
1tw4CHDFatty acid-binding protein, liver/0.442
1ywnLIFVascular endothelial growth factor receptor 22.7.10.10.442
1zrzBI1Protein kinase C iota type2.7.11.130.442
2b9xFADPutative aminooxidase/0.442
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
2c6lDT4Cyclin-dependent kinase 22.7.11.220.442
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.442
2harOCCVitamin D3 receptor/0.442
2hc4VDXVitamin D3 receptor A/0.442
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.442
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.442
2qd9LGFMitogen-activated protein kinase 14/0.442
2qnqQN3Gag-Pol polyprotein3.4.23.160.442
2vgoAD5Aurora kinase B-A2.7.11.10.442
2vzmNRBCytochrome P450 monooxygenase PikC/0.442
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.442
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3qlsNDPDihydrofolate reductase1.5.1.30.442
3qyw6PBMitogen-activated protein kinase 12.7.11.240.442
3rmf20ZCyclin-dependent kinase 22.7.11.220.442
3uvr06FMitogen-activated protein kinase 14/0.442
3w0hW12Vitamin D3 receptor/0.442
3w5rLOAVitamin D3 receptor/0.442
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.442
4fyn0VETyrosine-protein kinase SYK2.7.10.20.442
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.442
4hee14RPeroxisome proliferator-activated receptor gamma/0.442
4ix5ANPUncharacterized protein/0.442
4kwi1TJReductase homolog/0.442
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.442
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.442
5eaiFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1c6yMK1Protease/0.441
1ee0CAA2-pyrone synthase/0.441
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.441
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1jipKTN6-deoxyerythronolide B hydroxylase/0.441
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.441
1meuDMPGag-Pol polyprotein3.4.23.160.441
1nzdUPGDNA beta-glucosyltransferase/0.441
1ohr1UNV-1 PROTEASE protein/0.441
1qbsDMPGag-Pol polyprotein3.4.23.160.441
1sn5T3Transthyretin/0.441
1t7j478Gag-Pol polyprotein3.4.23.160.441
1t85CAMCamphor 5-monooxygenase1.14.15.10.441
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.441
2hqpNDPDihydrofolate reductase1.5.1.30.441
2j4dMHFCryptochrome DASH, chloroplastic/mitochondrial/0.441
2oalFADFlavin-dependent tryptophan halogenase RebH1.14.19.90.441
2q641UNGag-Pol polyprotein3.4.23.160.441
2r5tANPSerine/threonine-protein kinase Sgk12.7.11.10.441
2vwx7X4Ephrin type-B receptor 42.7.10.10.441
2wotZZGTGF-beta receptor type-12.7.11.300.441
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.441
2zlcVDXVitamin D3 receptor/0.441
3bc3OPTCathepsin L13.4.22.150.441
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.441
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.441
3hvcGG5Mitogen-activated protein kinase 14/0.441
3k9vCPS1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial/0.441
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.441
3mvm39PMitogen-activated protein kinase 14/0.441
3nbwTR4Ketohexokinase/0.441
3nup3NUCyclin-dependent kinase 62.7.11.220.441
3r1sX73Cyclin-dependent kinase 22.7.11.220.441
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4a86H35Major pollen allergen Bet v 1-A/0.441
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.441
4f9wLM4Mitogen-activated protein kinase 14/0.441
4fhi0S4Vitamin D3 receptor A/0.441
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.441
4ix4ADPUncharacterized protein/0.441
4jhz1KVBeta-glucuronidase3.2.1.310.441
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.441
4qmuSKESerine/threonine-protein kinase 242.7.11.10.441
4x5iFOLDihydrofolate reductase1.5.1.30.441
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.441
1c1dNAIPhenylalanine dehydrogenase/0.440
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
1jomFFODihydrofolate reductase1.5.1.30.440
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.440
1owlFADDeoxyribodipyrimidine photo-lyase4.1.99.30.440
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.440
1ra3MTXDihydrofolate reductase1.5.1.30.440
1rkgVD1Vitamin D3 receptor/0.440
1rkhVD2Vitamin D3 receptor/0.440
1yrcCAMCamphor 5-monooxygenase1.14.15.10.440
1yvj4STTyrosine-protein kinase JAK32.7.10.20.440
2ca0PXICytochrome P450 monooxygenase PikC/0.440
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2pym1UNGag-Pol polyprotein3.4.23.160.440
2qi7MZ9Gag-Pol polyprotein/0.440
2uxzHI1Gag-Pol polyprotein3.4.23.160.440
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.440
3bfb9ODPheromone-binding protein ASP1/0.440
3d0bSNXHeat shock protein HSP 90-alpha/0.440
3emg685Tyrosine-protein kinase SYK2.7.10.20.440
3fl8RARDihydrofolate reductase/0.440
3hp2P36Mitogen-activated protein kinase 14/0.440
3js2VM1Fibroblast growth factor receptor 1/0.440
3m7rVDXVitamin D3 receptor/0.440
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.440
3tmz06XCytochrome P450 2B41.14.14.10.440
3zsi52PMitogen-activated protein kinase 14/0.440
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.440
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.440
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.440
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.440
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.440
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.440
4upjU04Gag-Pol polyprotein/0.440
5aabVGHALK tyrosine kinase receptor2.7.10.10.440
5c8yACPTubulin tyrosine ligase/0.440
5ks72BACarnitine transport ATP-binding protein OpuCA3.6.3.320.440
6cp4CAMCamphor 5-monooxygenase1.14.15.10.440