sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3qyo | Q24 | Dihydrofolate reductase | 1.5.1.3 | 1.000 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.661 | |
| 3frf | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.635 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.633 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.626 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.619 | |
| 3tq9 | MTX | Dihydrofolate reductase | / | 0.616 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.615 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.610 | |
| 1rx3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.610 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.610 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.610 | |
| 1dg5 | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.607 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.607 | |
| 3r33 | 6ME | Dihydrofolate reductase | 1.5.1.3 | 0.604 | |
| 4ixe | IXE | Dihydrofolate reductase | 1.5.1.3 | 0.604 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.602 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.600 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.599 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.599 | |
| 3dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.594 | |
| 4nx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.592 | |
| 1qzf | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.591 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.588 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.588 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.587 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.586 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.586 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.585 | |
| 3qly | 55V | Uncharacterized protein | / | 0.585 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.585 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.585 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.584 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.583 | |
| 4ixg | IXG | Dihydrofolate reductase | 1.5.1.3 | 0.582 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.580 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.580 | |
| 3sh2 | 5DR | Dihydrofolate reductase | 1.5.1.3 | 0.579 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.578 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.577 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.577 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.575 | |
| 4p66 | MTX | Dihydrofolate reductase | / | 0.575 | |
| 1jom | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.574 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.574 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 3fyw | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.573 | |
| 3srr | Q20 | Dihydrofolate reductase | 1.5.1.3 | 0.573 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.572 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.571 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.570 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.569 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 1rg7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 3m08 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.568 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.567 | |
| 4eil | FOL | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.567 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.566 | |
| 3tqb | FOL | Dihydrofolate reductase | / | 0.565 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.565 | |
| 1df7 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.564 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.563 | |
| 2w9g | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
| 3fyv | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.563 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.562 | |
| 1dg7 | WRB | Dihydrofolate reductase | 1.5.1.3 | 0.560 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.560 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.559 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.559 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.559 | |
| 1hfp | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.558 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.558 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.557 | |
| 3srq | Q19 | Dihydrofolate reductase | 1.5.1.3 | 0.557 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.556 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.556 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.555 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
| 1rb3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.554 | |
| 3sa1 | 6DR | Dihydrofolate reductase | / | 0.554 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.554 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.553 | |
| 1dra | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.551 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.550 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.550 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.549 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.549 | |
| 3sru | Q26 | Dihydrofolate reductase | 1.5.1.3 | 0.547 | |
| 3cse | N22 | Uncharacterized protein | / | 0.546 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.544 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.544 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.543 | |
| 3ix9 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.541 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.540 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.539 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.539 | |
| 3fl8 | RAR | Dihydrofolate reductase | / | 0.539 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 1rf7 | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.538 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.537 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.536 | |
| 3d80 | Q22 | Dihydrofolate reductase | 1.5.1.3 | 0.536 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.536 | |
| 3eel | 53T | Uncharacterized protein | / | 0.536 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.535 | |
| 1ddr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.534 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.532 | |
| 2w3w | VG9 | Dihydrofolate reductase | / | 0.532 | |
| 3eek | 53S | Uncharacterized protein | / | 0.532 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.532 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.531 | |
| 4ele | 31I | Dihydrofolate reductase | / | 0.530 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.529 | |
| 1dis | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.528 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.527 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.527 | |
| 3fre | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.526 | |
| 3fl9 | TOP | Dihydrofolate reductase | / | 0.525 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.525 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.524 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.523 | |
| 4elh | 53I | Dihydrofolate reductase | / | 0.523 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.523 | |
| 4m7v | RAR | Dihydrofolate reductase | / | 0.523 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.522 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.522 | |
| 3eem | 53V | Uncharacterized protein | / | 0.521 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.520 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.519 | |
| 3tq8 | TOP | Dihydrofolate reductase | / | 0.519 | |
| 4qi9 | MTX | Dihydrofolate reductase | / | 0.519 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.516 | |
| 2bla | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.516 | |
| 3fra | I2H | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.515 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.514 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.514 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.513 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.513 | |
| 4x5f | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.512 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.511 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.511 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.510 | |
| 1bzf | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.509 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.508 | |
| 3sw8 | 5LI | Peptide deformylase | / | 0.507 | |
| 2ayr | L4G | Estrogen receptor | / | 0.506 | |
| 1s3y | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.505 | |
| 4dph | P65 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.505 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.505 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.503 | |
| 3eej | 53R | Uncharacterized protein | / | 0.503 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.503 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.502 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.501 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 3srs | M23 | Dihydrofolate reductase | 1.5.1.3 | 0.500 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.499 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.499 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.498 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.498 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.498 | |
| 1u72 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.497 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.496 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.496 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.496 | |
| 4eh4 | IRG | Mitogen-activated protein kinase 14 | / | 0.496 | |
| 1sej | F89 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.494 | |
| 4p68 | MTX | Dihydrofolate reductase | / | 0.494 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.493 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.493 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.493 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.492 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.491 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.490 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.489 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.488 | |
| 2fai | 459 | Estrogen receptor | / | 0.488 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.488 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.487 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.487 | |
| 1l2i | ETC | Estrogen receptor | / | 0.486 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.486 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.485 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.485 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.484 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.484 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.484 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.484 | |
| 3m09 | RAR | Dihydrofolate reductase | 1.5.1.3 | 0.484 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.484 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.484 | |
| 1dhj | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.483 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.483 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.482 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.482 | |
| 4e6a | 0O9 | Mitogen-activated protein kinase 14 | / | 0.482 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.482 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.482 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.481 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.481 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.481 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.480 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.480 | |
| 3htj | ET | EbrA repressor | / | 0.480 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.480 | |
| 1nce | CB3 | Thymidylate synthase | / | 0.479 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.479 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.479 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.479 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.479 | |
| 2uxh | QUE | HTH-type transcriptional regulator TtgR | / | 0.479 | |
| 3of1 | CMP | cAMP-dependent protein kinase regulatory subunit | / | 0.479 | |
| 3sr5 | Q12 | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.479 | |
| 4b8u | IBK | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.479 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.478 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.478 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.477 | |
| 3a0i | AJI | Glucokinase | 2.7.1.2 | 0.477 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.477 | |
| 4kak | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.477 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.476 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 4o95 | 245 | Cytokinin dehydrogenase 4 | / | 0.476 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.475 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.475 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.475 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.474 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 3p9t | TCL | Repressor | / | 0.474 | |
| 3rg9 | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.474 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.474 | |
| 1ohj | COP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 2jfa | RAL | Estrogen receptor | / | 0.473 | |
| 2mm3 | CHO | Gastrotropin | / | 0.473 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.473 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.473 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.473 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.473 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.473 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.472 | |
| 4eh8 | IRG | Mitogen-activated protein kinase 14 | / | 0.472 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.472 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.471 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.471 | |
| 2yis | I46 | Mitogen-activated protein kinase 14 | / | 0.471 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.471 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.471 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.471 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.471 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.471 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.470 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.470 | |
| 4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.470 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.470 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.469 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.469 | |
| 3d74 | NBB | Pheromone-binding protein ASP1 | / | 0.469 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.469 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.469 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.469 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.468 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.468 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.468 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.468 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.468 | |
| 4cav | MYA | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.468 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.468 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.467 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.467 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.467 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.467 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 1pkf | EPD | Epothilone C/D epoxidase | 1.14 | 0.466 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.466 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.466 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.466 | |
| 2rht | C1E | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.466 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.466 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.466 | |
| 3r02 | UNM | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.466 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.466 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.466 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.466 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.465 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.465 | |
| 2agv | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.465 | |
| 2c3o | TPP | Pyruvate synthase | / | 0.465 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.465 | |
| 4ixc | 1JD | Glucokinase | 2.7.1.2 | 0.465 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.465 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.464 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.464 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.464 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.464 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.464 | |
| 2p15 | EZT | Estrogen receptor | / | 0.464 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 2vss | ACO | Hydroxycinnamoyl-CoA hydratase-lyase | 4.1.2.41 | 0.464 | |
| 2xiz | XIZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.464 | |
| 3tky | N7I | (Iso)eugenol O-methyltransferase | 2.1.1.146 | 0.464 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.464 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.464 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.463 | |
| 2d0k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.463 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.463 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.463 | |
| 3d7k | D7K | Benzaldehyde lyase | / | 0.463 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.463 | |
| 4ax8 | ADP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.463 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.463 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.463 | |
| 4kao | KAO | Focal adhesion kinase 1 | 2.7.10.2 | 0.463 | |
| 4mlh | VO2 | Glucokinase | 2.7.1.2 | 0.463 | |
| 4pp6 | STL | Estrogen receptor | / | 0.463 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.463 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 1s3w | TQT | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.462 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.462 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.462 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.462 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3nxv | D2F | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.462 | |
| 4eh5 | IRG | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.462 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.461 | |
| 1fko | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.461 | |
| 1rt5 | UC2 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.461 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 2g44 | T3O | Estrogen receptor | / | 0.461 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.461 | |
| 3c1x | CKK | Hepatocyte growth factor receptor | 2.7.10.1 | 0.461 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.461 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.461 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.461 | |
| 4a5l | NDP | Thioredoxin reductase | / | 0.461 | |
| 4c8b | 0LI | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.461 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.461 | |
| 1dtn | APG | Mandelate racemase | / | 0.460 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.460 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2ihu | TP9 | N(2)-(2-carboxyethyl)arginine synthase | / | 0.460 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.460 | |
| 2y0j | AXC | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 4i9i | 1DY | Tankyrase-1 | 2.4.2.30 | 0.460 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.460 | |
| 1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.459 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.459 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.459 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.459 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.459 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.459 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
| 3bxx | QUE | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.459 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.459 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.459 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.459 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.459 | |
| 4kd7 | 9DR | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.459 | |
| 5cb5 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.459 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.458 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.458 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.458 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.458 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.458 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.458 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.458 | |
| 3fal | REA | Retinoic acid receptor RXR-alpha | / | 0.458 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.458 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.458 | |
| 3zsg | T75 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 4dma | 0L8 | Estrogen receptor | / | 0.458 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 4j7x | SAS | Sepiapterin reductase | 1.1.1.153 | 0.458 | |
| 1axw | MTX | Thymidylate synthase | / | 0.457 | |
| 1kij | NOV | DNA gyrase subunit B | / | 0.457 | |
| 1mc5 | AHE | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.457 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.457 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.457 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.457 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.457 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.457 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.457 | |
| 3ghh | 2NF | CD38 molecule | / | 0.457 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3qfv | NM7 | Serine/threonine-protein kinase MRCK beta | 2.7.11.1 | 0.457 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.457 | |
| 4eh6 | IRG | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.457 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.457 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 1lud | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1m52 | P17 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.456 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.456 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 2g5o | DRQ | Estrogen receptor | / | 0.456 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.456 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3uud | EST | Estrogen receptor | / | 0.456 | |
| 3x0a | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.456 | |
| 4alh | A9P | Bromodomain-containing protein 2 | / | 0.456 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.455 | |
| 2i1v | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.455 | |
| 2ocf | EST | Estrogen receptor | / | 0.455 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.455 | |
| 2wow | NDP | Trypanothione reductase | / | 0.455 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.455 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.455 | |
| 3ce3 | 1FN | Hepatocyte growth factor receptor | 2.7.10.1 | 0.455 | |
| 3dh0 | SAM | Uncharacterized protein | / | 0.455 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 3iw4 | LW4 | Protein kinase C alpha type | 2.7.11.13 | 0.455 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 3nxr | D2D | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3zns | NU7 | Histone deacetylase 7 | 3.5.1.98 | 0.455 | |
| 4eh7 | IRG | Mitogen-activated protein kinase 14 | / | 0.455 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.455 | |
| 4kbn | 25U | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4l0q | NAD | Alcohol dehydrogenase class-3 | / | 0.455 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.455 | |
| 7prc | CET | Reaction center protein L chain | / | 0.455 | |
| 1a4l | DCF | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.454 | |
| 1nde | MON | Estrogen receptor beta | / | 0.454 | |
| 1s3v | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.454 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.454 | |
| 2v0m | KLN | Cytochrome P450 3A4 | / | 0.454 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.454 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.454 | |
| 3ldo | ANP | 78 kDa glucose-regulated protein | / | 0.454 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.454 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.454 | |
| 4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.454 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.454 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.453 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.453 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.453 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.453 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.453 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 3c3e | FO1 | 2-phospho-L-lactate transferase | / | 0.453 | |
| 3hll | I46 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 3ngl | NAP | Bifunctional protein FolD | / | 0.453 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3q2m | CKI | Spectinomycin phosphotransferase | / | 0.453 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.453 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.453 | |
| 3zv5 | BPY | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.453 | |
| 4cry | ACO | PanD regulatory factor | / | 0.453 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 4g1d | 0VK | Vitamin D3 receptor A | / | 0.453 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.453 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.453 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.453 | |
| 1k6m | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 1 | 2.7.1.105 | 0.452 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.452 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.452 | |
| 2gq3 | COA | Malate synthase G | / | 0.452 | |
| 2p1d | SAH | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.452 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.452 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.452 | |
| 3iw8 | HIZ | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.452 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.452 | |
| 3upk | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.452 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.452 | |
| 4a99 | MIY | TetX family tetracycline inactivation enzyme | / | 0.452 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.452 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.452 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 1orh | SAH | Protein arginine N-methyltransferase 1 | / | 0.451 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.451 | |
| 1yin | CM3 | Estrogen receptor | / | 0.451 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.451 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3uvv | REA | Retinoic acid receptor RXR-alpha | / | 0.451 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.451 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.451 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.451 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.451 | |
| 4egn | TWO | Cytochrome P450 | / | 0.451 | |
| 4eh3 | IRG | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4kyh | ZST | Lactoylglutathione lyase | 4.4.1.5 | 0.451 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.451 | |
| 4ug7 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.451 | |
| 4v26 | TF3 | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.451 | |
| 1e7w | MTX | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 1efz | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.450 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.450 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.450 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.450 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.450 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.450 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.450 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.450 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.450 | |
| 2pmd | GNP | Translation initiation factor 2 subunit gamma | / | 0.450 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.450 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3hz1 | 37D | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3nax | MP7 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.450 | |
| 4bfr | J82 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform | 2.7.1.153 | 0.450 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.450 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.450 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.450 | |
| 5ify | TRH | Glucose-1-phosphate thymidylyltransferase | / | 0.450 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.449 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.449 | |
| 1qxo | FMN | Chorismate synthase | / | 0.449 | |
| 1syn | F89 | Thymidylate synthase | / | 0.449 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.449 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.449 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.449 | |
| 2xvv | 9DN | Serum albumin | / | 0.449 | |
| 3dqw | AGS | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.449 | |
| 3k45 | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.449 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4bbh | YBN | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 4flp | JQ1 | Bromodomain testis-specific protein | / | 0.449 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.449 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.449 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4tyj | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.449 | |
| 5je2 | SAH | Methyl transferase | / | 0.449 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.448 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 1ndz | FR5 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1uy6 | PU3 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 1xpc | AIT | Estrogen receptor | / | 0.448 | |
| 2f2c | AP9 | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.448 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 2on6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2wpw | ACO | Orf14 | / | 0.448 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 3dol | GWI | Pol protein | / | 0.448 | |
| 3f0a | ACO | Spermidine N(1)-acetyltransferase | / | 0.448 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.448 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.448 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4agw | NG7 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.448 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.448 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 5a3c | NAD | SIR2 family protein | / | 0.448 | |
| 5dq8 | FLF | Transcriptional enhancer factor TEF-4 | / | 0.448 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.447 | |
| 1f5f | DHT | Sex hormone-binding globulin | / | 0.447 | |
| 1pq6 | 965 | Oxysterols receptor LXR-beta | / | 0.447 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1sre | HAB | Streptavidin | / | 0.447 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.447 | |
| 1u9e | 397 | Estrogen receptor beta | / | 0.447 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.447 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.447 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.447 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.447 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2yxj | N3C | Bcl-2-like protein 1 | / | 0.447 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3g49 | 3G4 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3k3i | I46 | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 3m7r | VDX | Vitamin D3 receptor | / | 0.447 | |
| 3t7v | SAM | 3-methylornithine synthase | / | 0.447 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.447 | |
| 4aql | TXC | Guanine deaminase | 3.5.4.3 | 0.447 | |
| 4at2 | ASD | Possible succinate dehydrogenase | / | 0.447 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.447 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.447 | |
| 4eh9 | IRG | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4iwc | 1GV | Estrogen receptor | / | 0.447 | |
| 4j4v | SVR | Nucleocapsid protein | / | 0.447 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.447 | |
| 1db5 | 6IN | Phospholipase A2, membrane associated | / | 0.446 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.446 | |
| 1jut | LYD | Thymidylate synthase | / | 0.446 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.446 | |
| 2dqs | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.446 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.446 | |
| 2uza | HTL | Pyruvate synthase | / | 0.446 | |
| 2vag | V25 | Dual specificity protein kinase CLK1 | 2.7.12.1 | 0.446 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2x1e | X1E | Acyl-coenzyme A:6-aminopenicillanic-acid-acyltransferase 40 kDa form | 2.3.1.164 | 0.446 | |
| 2x20 | PID | Peridinin-chlorophyll a-binding protein 1, chloroplastic | / | 0.446 | |
| 3bgr | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.446 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.446 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.446 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3upy | FOM | Oxidoreductase, putative | / | 0.446 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.446 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.446 | |
| 3x06 | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.446 | |
| 4dli | IRG | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 4eiy | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.446 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.446 | |
| 4myq | 19T | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.446 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 5dx3 | EST | Estrogen receptor | / | 0.446 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 6prc | CEB | Reaction center protein L chain | / | 0.446 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.446 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.445 | |
| 1mdl | RMN | Mandelate racemase | / | 0.445 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.445 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.445 | |
| 1zky | 689 | Estrogen receptor | / | 0.445 | |
| 2giu | FBR | Estrogen receptor beta | / | 0.445 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.445 | |
| 2wms | ZYS | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2yix | YIX | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.445 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.445 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.445 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.445 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.445 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.445 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4iw6 | 1GU | Estrogen receptor | / | 0.445 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 4uog | YYY | Nucleoside diphosphate kinase | / | 0.445 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.445 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.444 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.444 | |
| 1jlq | SBN | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.444 | |
| 1kek | HTL | Pyruvate synthase | / | 0.444 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1m8h | 6NI | Nitric oxide synthase, inducible | 1.14.13.39 | 0.444 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.444 | |
| 1wrl | TFP | Troponin C, slow skeletal and cardiac muscles | / | 0.444 | |
| 2c3d | COM | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.444 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.444 | |
| 2lf1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2od7 | A1R | NAD-dependent protein deacetylase HST2 | 3.5.1 | 0.444 | |
| 2oli | IOP | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.444 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.444 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.444 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.444 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.444 | |
| 3d57 | 4HY | Thyroid hormone receptor beta | / | 0.444 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3mne | DEX | Glucocorticoid receptor | / | 0.444 | |
| 3nxy | D2H | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.444 | |
| 3vet | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.444 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.444 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.444 | |
| 4ivy | 1GT | Estrogen receptor | / | 0.444 | |
| 4jq4 | IMN | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 4l8u | 9AZ | Serum albumin | / | 0.444 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4tjy | 3GN | Tankyrase-2 | 2.4.2.30 | 0.444 | |
| 1iky | MSD | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.443 | |
| 2qa8 | GEN | Estrogen receptor | / | 0.443 | |
| 2vcg | S17 | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.443 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.443 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.443 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.443 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 3oap | REA | Retinoic acid receptor RXR-alpha | / | 0.443 | |
| 3t9i | 3T9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4dsb | A8S | Abscisic acid receptor PYL3 | / | 0.443 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.443 | |
| 4oth | DRN | Serine/threonine-protein kinase N1 | / | 0.443 | |
| 4qrc | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.443 | |
| 5c8a | 5AD | Probable transcriptional regulator | / | 0.443 | |
| 5dxg | EST | Estrogen receptor | / | 0.443 | |
| 1dkf | BMS | Retinoic acid receptor alpha | / | 0.442 | |
| 1th6 | OIN | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.442 | |
| 1y6b | AAX | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.442 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2c3u | 2TP | Pyruvate synthase | / | 0.442 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.442 | |
| 2igx | A1T | Plasmepsin 2 | / | 0.442 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.442 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2q7g | CCL | Pyrrolysine--tRNA ligase | / | 0.442 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.442 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3r7m | SUZ | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.442 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.442 | |
| 3wiy | LC6 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.442 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.442 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.442 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.442 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.442 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4twp | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 5bt4 | 2LO | Bromodomain-containing protein 4 | / | 0.442 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.442 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1lhv | NOG | Sex hormone-binding globulin | / | 0.441 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.441 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.441 | |
| 1yim | CM4 | Estrogen receptor | / | 0.441 | |
| 2bxm | IMN | Serum albumin | / | 0.441 | |
| 2e9v | 85A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 2fpc | SCG | Strictosidine synthase | 4.3.3.2 | 0.441 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.441 | |
| 2jfz | 003 | Glutamate racemase | / | 0.441 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.441 | |
| 2pda | TPP | Pyruvate synthase | / | 0.441 | |
| 2pog | WST | Estrogen receptor | / | 0.441 | |
| 2qhx | FE1 | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 2wd7 | VGD | Pteridine reductase | / | 0.441 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.441 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.441 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 3drr | R8E | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.441 | |
| 3nj0 | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.441 | |
| 3pd5 | TSB | Threonine--tRNA ligase | 6.1.1.3 | 0.441 | |
| 3qpv | ADP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 3 | 2.7.1.105 | 0.441 | |
| 3qs8 | 17D | Anthranilate phosphoribosyltransferase | / | 0.441 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.441 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.441 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.441 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.441 | |
| 4bwa | N0B | Pyrrolysine--tRNA ligase | / | 0.441 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.441 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.441 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.441 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.441 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.441 | |
| 4mle | VO1 | Glucokinase | 2.7.1.2 | 0.441 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4yek | THM | Thymidine phosphorylase | / | 0.441 | |
| 5c8d | 5AD | Probable transcriptional regulator | / | 0.441 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.441 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1ep4 | S11 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 1fr8 | GDU | Beta-1,4-galactosyltransferase 1 | / | 0.440 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1pnq | NDP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.440 | |
| 1u3r | 338 | Estrogen receptor beta | / | 0.440 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.440 | |
| 1zz1 | SHH | Histone deacetylase-like amidohydrolase | 3.5.1 | 0.440 | |
| 2bil | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.440 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 2oyf | IAC | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.440 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.440 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.440 | |
| 3dko | IHZ | Ephrin type-A receptor 7 | 2.7.10.1 | 0.440 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.440 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.440 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3jzf | JZK | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.440 | |
| 3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 3up3 | XCA | aceDAF-12 | / | 0.440 | |
| 3v1m | HPK | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.440 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.440 | |
| 3vw8 | DF6 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.440 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.440 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.440 | |
| 4h4o | 506 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.440 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.440 | |
| 5gcn | COA | HAT A1 | / | 0.440 |