sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.899 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.875 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.869 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.865 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.864 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.863 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.854 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.839 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.839 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.838 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.834 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.830 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.823 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.823 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.798 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.788 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.783 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.767 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.767 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.748 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.745 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.731 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.731 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.701 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.700 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.699 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.699 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.699 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.650 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.604 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.598 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.591 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.585 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.581 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.580 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.573 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.562 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.559 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.555 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.552 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.541 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.537 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.534 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.519 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.515 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.513 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.509 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.506 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.503 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.503 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.501 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.499 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.499 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.498 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.496 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.495 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.494 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.494 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.493 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.491 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.490 | |
| 4e2b | FMN | Dehydrogenase | / | 0.489 | |
| 4jic | FMN | GTN Reductase | / | 0.489 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.488 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.488 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.487 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.487 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.485 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.485 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.483 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.482 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.482 | |
| 3eku | CY9 | Actin-5C | / | 0.482 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.482 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.481 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.481 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.481 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.480 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.480 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.480 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.480 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.479 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.479 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.479 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.479 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.478 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.478 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.478 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.477 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.477 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.477 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.476 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.476 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.475 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.474 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.473 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.473 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.473 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.473 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.473 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.472 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.472 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.472 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.472 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.472 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.472 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.471 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.471 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.471 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.471 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.471 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.470 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.469 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.468 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.468 | |
| 3e6e | DCS | Alanine racemase | / | 0.468 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.468 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.468 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.468 | |
| 4utl | FNR | Xenobiotic reductase | / | 0.468 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.468 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.467 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.467 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.467 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.467 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.467 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.467 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.467 | |
| 4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.467 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.467 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.466 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.466 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.466 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.466 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.466 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.466 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.466 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.466 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.465 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.465 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.465 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.465 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.465 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.465 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.465 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.465 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.465 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.464 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.464 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.464 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.464 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4rel | KMP | Glycosyltransferase | / | 0.464 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.464 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.463 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.463 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.463 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.463 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.463 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.463 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.463 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.462 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.462 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.462 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.462 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.462 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.462 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.462 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.461 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.461 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.461 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.461 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.461 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.461 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.461 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.460 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.460 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.460 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4j7h | TRH | PCZA361.3 | / | 0.460 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.460 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.459 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.459 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.459 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.459 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.458 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.458 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.458 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.458 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.458 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.458 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.458 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.458 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.458 | |
| 1e2n | RCA | Thymidine kinase | / | 0.457 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.457 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.457 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.457 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.457 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.457 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.457 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.456 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.456 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.456 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.456 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.456 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.456 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.456 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.456 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.456 | |
| 4e2d | FMN | Dehydrogenase | / | 0.456 | |
| 4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.456 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.456 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.456 | |
| 1e6v | COM | Methyl-coenzyme M reductase I subunit alpha | / | 0.455 | |
| 1e6v | COM | Methyl coenzyme M reductase, beta subunit | / | 0.455 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.455 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.455 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.455 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.455 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.455 | |
| 2dxf | GNP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.455 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.455 | |
| 2r5n | TPP | Transketolase 1 | / | 0.455 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.455 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.455 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.455 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.455 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.455 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4bri | UNP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.455 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.455 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.454 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.454 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.454 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.454 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.454 | |
| 4uoc | NCN | CinA-like protein | / | 0.454 | |
| 1itz | TPP | Transketolase, chloroplastic | 2.2.1.1 | 0.453 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.453 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.453 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.453 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.453 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.453 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.453 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.453 | |
| 3qvi | K95 | HAP protein | / | 0.453 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.453 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.453 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4iah | 1DX | Alr2278 protein | / | 0.453 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.452 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.452 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.452 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.452 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.452 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.452 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.452 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.451 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.451 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.451 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.451 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.451 | |
| 3wag | TYD | Glycosyltransferase | / | 0.451 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.451 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.450 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.450 | |
| 2nvd | ITB | Aldose reductase | 1.1.1.21 | 0.450 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.450 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.450 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.450 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.450 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.450 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.450 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.450 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.450 | |
| 4yvj | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.450 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.449 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.449 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.449 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.449 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.449 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.449 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.449 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.449 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.449 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.449 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.449 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.449 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.449 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.448 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.448 | |
| 2ohv | NHL | Glutamate racemase | / | 0.448 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.448 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.448 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.448 | |
| 4iae | 1DX | Alr2278 protein | / | 0.448 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.448 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.448 | |
| 4yp1 | 2BA | Stimulator of interferon genes protein | / | 0.448 | |
| 5cyo | GDP | Septin-9 | / | 0.448 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.447 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.447 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.447 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.447 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.447 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.447 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.447 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.447 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.447 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.447 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.447 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.447 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.447 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.447 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.447 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.447 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.447 | |
| 5ilw | URI | Ribosome inactivating protein | / | 0.447 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.446 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.446 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.446 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.446 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.446 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.446 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.446 | |
| 4c72 | TLG | 3-oxoacyl-ACP synthase | / | 0.446 | |
| 4e2x | TYD | Methyltransferase | / | 0.446 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.446 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.446 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.446 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.445 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.445 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.445 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.445 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.445 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.445 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.445 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.445 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.445 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.445 | |
| 3dhc | CYK | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.445 | |
| 3eks | CY9 | Actin-5C | / | 0.445 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.445 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.445 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.445 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.445 | |
| 3v2u | ATP | Protein GAL3 | / | 0.445 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.445 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4hyv | PEP | Pyruvate kinase 1 | 2.7.1.40 | 0.445 | |
| 4ise | 1FW | Glucokinase | 2.7.1.2 | 0.445 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.445 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.445 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.444 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.444 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.444 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.444 | |
| 2abj | PLP | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.444 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.444 | |
| 2c92 | TP6 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2cmo | M1L | Glutamate receptor 2 | / | 0.444 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.444 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.444 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.444 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.444 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.444 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.444 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4fud | 6UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.444 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.444 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.443 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.443 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.443 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1sb8 | UD2 | WbpP | / | 0.443 | |
| 1swt | BTN | Streptavidin | / | 0.443 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 1v5z | 2HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.443 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.443 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.443 | |
| 1zdw | FLV | Prenyltransferase | / | 0.443 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.443 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.443 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.443 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.443 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.443 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.443 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.443 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.443 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.442 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.442 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.442 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.442 | |
| 1oyc | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.442 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.442 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.442 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.442 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.442 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.442 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.442 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.442 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.442 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.442 | |
| 3td7 | FAD | Probable FAD-linked sulfhydryl oxidase R596 | 1.8.3.2 | 0.442 | |
| 3wcz | NAP | Aldo-keto reductase AKR2E4 | / | 0.442 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.442 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.442 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.442 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.442 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.442 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.441 | |
| 1b8u | NAD | Malate dehydrogenase | / | 0.441 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.441 | |
| 1c7o | PPG | Hemolysin | / | 0.441 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.441 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.441 | |
| 2a5c | 8DA | Avidin | / | 0.441 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.441 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.441 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.441 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.441 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.441 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.441 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.441 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.440 | |
| 1svm | ATP | Large T antigen | 3.6.4 | 0.440 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.440 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 2fr1 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.440 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.440 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.440 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.440 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.440 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3e39 | FMN | Nitroreductase | / | 0.440 | |
| 3fpa | DTB | ATP-dependent dethiobiotin synthetase BioD | / | 0.440 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.440 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.440 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.440 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.440 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.440 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.440 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.440 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.440 | |
| 4jb1 | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.440 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.440 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.440 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.440 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.440 |