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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2broDF2Serine/threonine-protein kinase Chk12.7.11.1

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
2broDF2Serine/threonine-protein kinase Chk12.7.11.11.000
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.613
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.598
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.591
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.584
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.582
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.578
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.569
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.566
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.562
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.562
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.561
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.560
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.559
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.558
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.558
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.553
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.552
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.552
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.552
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.551
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.550
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.549
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.548
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.547
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.542
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.542
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.541
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.541
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.539
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.538
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.538
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.537
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.535
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.535
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.534
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.533
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.532
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.532
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.531
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.531
2hog710Serine/threonine-protein kinase Chk12.7.11.10.530
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.530
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.530
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.529
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.529
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.527
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.527
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.527
5auuLU2Death-associated protein kinase 12.7.11.10.527
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.524
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.523
4qmySTUSerine/threonine-protein kinase 242.7.11.10.523
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.522
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.522
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.522
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.522
3zh8C58Protein kinase C iota type2.7.11.130.521
1zrzBI1Protein kinase C iota type2.7.11.130.520
1zys199Serine/threonine-protein kinase Chk12.7.11.10.520
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.520
3gubGUBDeath-associated protein kinase 12.7.11.10.520
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.520
2x1nX1NCyclin-dependent kinase 22.7.11.220.519
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.519
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.518
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.517
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.516
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.516
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.516
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.516
4gmy0X5Tyrosine-protein kinase JAK2/0.515
4qmzB49Serine/threonine-protein kinase 242.7.11.10.515
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.514
3c4xATPRhodopsin kinase/0.512
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.511
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.511
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.510
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.510
1oiyN41Cyclin-dependent kinase 22.7.11.220.509
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.509
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.509
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.509
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.509
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.508
2iw84SPCyclin-dependent kinase 22.7.11.220.508
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.508
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.508
2i40BLZCyclin-dependent kinase 22.7.11.220.507
2wihP48Cyclin-dependent kinase 22.7.11.220.507
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.507
1xjdSTUProtein kinase C theta type2.7.11.130.506
3bhtMFRCyclin-dependent kinase 22.7.11.220.506
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.506
3sheI85MAP kinase-activated protein kinase 32.7.11.10.506
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.506
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.505
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.505
1unlRRCCyclin-dependent-like kinase 52.7.11.10.504
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.504
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.504
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.504
4qmpDKISerine/threonine-protein kinase 242.7.11.10.503
2ghlLIBMitogen-activated protein kinase 14/0.500
3hx4ANPCalmodulin-domain protein kinase 1/0.500
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.500
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.500
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.500
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.500
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.500
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.500
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.498
2wxvWXVCyclin-dependent kinase 22.7.11.220.498
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.498
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.498
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.498
3a62STURibosomal protein S6 kinase beta-12.7.11.10.498
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.498
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.498
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.497
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.497
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.497
1pkdUCNCyclin-dependent kinase 22.7.11.220.496
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.496
3rni21ZCyclin-dependent kinase 22.7.11.220.496
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.496
3t8oATPRhodopsin kinase/0.495
1fvv107Cyclin-dependent kinase 22.7.11.220.494
1h1s4SPCyclin-dependent kinase 22.7.11.220.494
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.494
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.494
3dogNNNCyclin-dependent kinase 22.7.11.220.494
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.494
1h1r6CPCyclin-dependent kinase 22.7.11.220.493
1zltHYMSerine/threonine-protein kinase Chk12.7.11.10.493
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.493
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.493
3bqr4RBDeath-associated protein kinase 3/0.493
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.493
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.493
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.493
5e8xSTUTGF-beta receptor type-12.7.11.300.493
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.492
2w06FRVCyclin-dependent kinase 22.7.11.220.492
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.492
4j97ACPFibroblast growth factor receptor 2/0.492
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.492
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.492
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.491
2xikJ60Serine/threonine-protein kinase 252.7.11.10.491
3gu6ADPDeath-associated protein kinase 12.7.11.10.491
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.491
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.491
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.490
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.490
2j0lANPFocal adhesion kinase 12.7.10.20.490
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.490
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.490
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.489
3hllI45Mitogen-activated protein kinase 14/0.489
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.489
4gk3L87Ephrin type-A receptor 32.7.10.10.489
5auwQUEDeath-associated protein kinase 12.7.11.10.489
2dwbANPAurora kinase A2.7.11.10.488
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.488
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.488
4e4m0NHTyrosine-protein kinase JAK2/0.488
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.487
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.487
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.487
3tnwF18Cyclin-dependent kinase 22.7.11.220.487
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.487
4hvh19RTyrosine-protein kinase JAK32.7.10.20.487
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.486
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.486
3gu83GUDeath-associated protein kinase 12.7.11.10.486
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.486
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.486
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.486
4y93746Tyrosine-protein kinase/0.486
4yuqKS1Calmodulin-like domain protein kinase/0.486
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.485
2jkkBI9Focal adhesion kinase 12.7.10.20.485
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.485
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.485
3zewSTUEphrin type-B receptor 42.7.10.10.485
4bgg844Activin receptor type-12.7.11.300.485
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.485
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.485
4k33ACPFibroblast growth factor receptor 32.7.10.10.485
2cchATPCyclin-dependent kinase 22.7.11.220.484
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.484
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.484
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.484
1p4fDRGDeath-associated protein kinase 12.7.11.10.483
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.483
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.483
3du8553Glycogen synthase kinase-3 beta2.7.11.260.483
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.483
3i60E86Mitogen-activated protein kinase 12.7.11.240.483
4c02TAKActivin receptor type-12.7.11.300.483
4ct1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.483
4fod0UVALK tyrosine kinase receptor2.7.10.10.483
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.483
5auxKMPDeath-associated protein kinase 12.7.11.10.483
2bkzSBCCyclin-dependent kinase 22.7.11.220.482
2c6tDT5Cyclin-dependent kinase 22.7.11.220.482
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.482
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.482
3rpv26ZCyclin-dependent kinase 22.7.11.220.482
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.482
4fob0USALK tyrosine kinase receptor2.7.10.10.482
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.482
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.481
2w05FRTCyclin-dependent kinase 22.7.11.220.481
3bi6396Wee1-like protein kinase2.7.10.20.481
3qc9ADPRhodopsin kinase/0.481
3raiX85Cyclin-dependent kinase 22.7.11.220.481
4c57FEFCyclin-G-associated kinase2.7.11.10.481
4dgnLU2Casein kinase II subunit alpha2.7.11.10.481
4jqeANPCasein kinase II subunit alpha2.7.11.10.481
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.480
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.480
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.480
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.480
2y6o1N1Ephrin type-A receptor 42.7.10.10.480
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.480
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.480
4g2fC07Ephrin type-A receptor 32.7.10.10.480
2bhhRYUCyclin-dependent kinase 22.7.11.220.479
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.479
3eyhIZATyrosine-protein kinase JAK1/0.479
3s1dZIRCytokinin dehydrogenase 11.5.99.120.479
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.479
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.479
4btjATPTau-tubulin kinase 12.7.11.10.479
4gk2L66Ephrin type-A receptor 32.7.10.10.479
4jia1K3Tyrosine-protein kinase JAK2/0.479
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.478
2b7aIZATyrosine-protein kinase JAK2/0.478
2biyATP3-phosphoinositide-dependent protein kinase 12.7.11.10.478
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.478
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.478
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.478
4btjADPTau-tubulin kinase 12.7.11.10.478
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.477
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.477
2j0m4STFocal adhesion kinase 12.7.10.20.477
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.477
3lfqA28Cyclin-dependent kinase 22.7.11.220.477
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.477
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.477
3ormAGSSerine/threonine protein kinase/0.477
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.477
3r7iX9ICyclin-dependent kinase 22.7.11.220.477
3uli1N3Cyclin-dependent kinase 22.7.11.220.477
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.477
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.477
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.477
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.477
5cshATPCasein kinase II subunit alpha2.7.11.10.477
1oguST8Cyclin-dependent kinase 22.7.11.220.476
1rfvADPPyridoxal kinase2.7.1.350.476
3a7hATPSerine/threonine-protein kinase 242.7.11.10.476
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.476
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.476
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.476
3vf9477Tyrosine-protein kinase SYK2.7.10.20.476
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.476
4eok4SPCyclin-dependent kinase 22.7.11.220.476
5av4GENDeath-associated protein kinase 12.7.11.10.476
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.475
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.475
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.475
3pe2E1BCasein kinase II subunit alpha2.7.11.10.475
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.475
4fx360KCyclin-dependent kinase 22.7.11.220.475
4utdACPAurora kinase A2.7.11.10.475
1y91CT9Cyclin-dependent kinase 22.7.11.220.474
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.474
2uzbC75Cyclin-dependent kinase 22.7.11.220.474
2uzeC95Cyclin-dependent kinase 22.7.11.220.474
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.474
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.474
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.473
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.473
2ijmADPFocal adhesion kinase 12.7.10.20.473
2zbaZBATrichothecene 3-O-acetyltransferase/0.473
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.473
4dgo0JWCasein kinase II subunit alpha2.7.11.10.473
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.473
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.473
1g5sI17Cyclin-dependent kinase 22.7.11.220.472
2b53D23Cyclin-dependent kinase 22.7.11.220.472
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.472
2pwlACPFibroblast growth factor receptor 2/0.472
3mtfA3FActivin receptor type-12.7.11.300.472
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.472
4du82P0Mevalonate diphosphate decarboxylase/0.472
1cf3FADGlucose oxidase1.1.3.40.471
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.471
1wvxBD4Death-associated protein kinase 12.7.11.10.471
2izuP01Casein kinase I isoform gamma-32.7.11.10.471
2xngA0HAurora kinase A2.7.11.10.471
2znq401Peroxisome proliferator-activated receptor delta/0.471
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.471
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.471
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.471
1e9hINRCyclin-dependent kinase 22.7.11.220.470
1xe55FEPlasmepsin-23.4.23.390.470
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.470
2iw94SPCyclin-dependent kinase 22.7.11.220.470
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.470
3ibqATPPyridoxal kinase/0.470
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.470
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.470
4gk4L90Ephrin type-A receptor 32.7.10.10.470
5drdATPAurora kinase A2.7.11.10.470
1bxoPP7Penicillopepsin-13.4.23.200.469
1bygSTUTyrosine-protein kinase CSK/0.469
1m2qMNXCasein kinase II subunit alpha2.7.11.10.469
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.469
2uzdC85Cyclin-dependent kinase 22.7.11.220.469
2uzlC94Cyclin-dependent kinase 22.7.11.220.469
2x9fX9FEphrin type-B receptor 42.7.10.10.469
3r9dX6BCyclin-dependent kinase 22.7.11.220.469
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.469
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.469
1bwsNDPGDP-L-fucose synthase/0.468
1vi2NADQuinate/shikimate dehydrogenase/0.468
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.468
2qo9ANPEphrin type-A receptor 32.7.10.10.468
3d7kD7KBenzaldehyde lyase/0.468
3eljGS7Mitogen-activated protein kinase 82.7.11.240.468
3ezvEZVCyclin-dependent kinase 22.7.11.220.468
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.468
4nj32KDCyclin-dependent kinase 22.7.11.220.468
5auvAGIDeath-associated protein kinase 12.7.11.10.468
5av2KMPDeath-associated protein kinase 12.7.11.10.468
5dt3ATPAurora kinase A2.7.11.10.468
5f8eSAHPossible transcriptional regulatory protein/0.468
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.467
2f2cAP9Cyclin-dependent kinase 62.7.11.220.467
2j0j4STFocal adhesion kinase 12.7.10.20.467
2nniMTKCytochrome P450 2C8/0.467
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.467
2wpa889Cyclin-dependent kinase 22.7.11.220.467
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.467
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.467
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.467
3oom507Activin receptor type-12.7.11.300.467
3q3cNADNAD-dependent L-serine dehydrogenase/0.467
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.466
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.466
1rfuADPPyridoxal kinase2.7.1.350.466
2h96893Mitogen-activated protein kinase 82.7.11.240.466
2vd5BI8Myotonin-protein kinase2.7.11.10.466
2wotZZGTGF-beta receptor type-12.7.11.300.466
2xvdAS6Ephrin type-B receptor 42.7.10.10.466
3hekBD0Heat shock protein HSP 90-alpha/0.466
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.466
3o0g3O0Cyclin-dependent-like kinase 52.7.11.10.466
3qtxX43Cyclin-dependent kinase 22.7.11.220.466
3r9hZ67Cyclin-dependent kinase 22.7.11.220.466
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.466
4eor4SPCyclin-dependent kinase 22.7.11.220.466
4foc0UUALK tyrosine kinase receptor2.7.10.10.466
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.466
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.466
4tuvCPZCytochrome P450 1191.140.466
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.465
1oiuN76Cyclin-dependent kinase 22.7.11.220.465
2c5nCK8Cyclin-dependent kinase 22.7.11.220.465
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.465
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.465
3bhy7CPDeath-associated protein kinase 3/0.465
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.465
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.465
3tucFPWTyrosine-protein kinase SYK2.7.10.20.465
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.465
4bcnT9NCyclin-dependent kinase 22.7.11.220.465
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.465
4l9i8PRRhodopsin kinase/0.465
4nk92K5Fibroblast growth factor receptor 1/0.465
1nzdUPGDNA beta-glucosyltransferase/0.464
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.464
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.464
2zjwREFCasein kinase II subunit alpha2.7.11.10.464
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.464
3g70A5TRenin3.4.23.150.464
3qd03Q43-phosphoinositide-dependent protein kinase 12.7.11.10.464
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.464
3vf80JETyrosine-protein kinase SYK2.7.10.20.464
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.464
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4c35NU3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
4fkw62KCyclin-dependent kinase 22.7.11.220.464
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.464
5e8wSTUTGF-beta receptor type-12.7.11.300.464
2ckeIQUDeath-associated protein kinase 2/0.463
2po7CHDFerrochelatase, mitochondrial4.99.1.10.463
2pvnP63Casein kinase II subunit alpha2.7.11.10.463
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.463
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
3gwfFADCyclohexanone monooxygenase/0.463
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.463
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.463
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.463
4fv6E57Mitogen-activated protein kinase 12.7.11.240.463
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.463
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.463
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.463
5eccNAPDehydrofolate reductase type I/0.463
1lf3EH5Plasmepsin-23.4.23.390.462
2btrU73Cyclin-dependent kinase 22.7.11.220.462
2j0k4STFocal adhesion kinase 12.7.10.20.462
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.462
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.462
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.462
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.462
4n57ADPAPH(2'')-Id/0.462
1gih1PUCyclin-dependent kinase 22.7.11.220.461
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.461
2acxANPG protein-coupled receptor kinase 62.7.11.160.461
2b52D42Cyclin-dependent kinase 22.7.11.220.461
2p33J07Mitogen-activated protein kinase 102.7.11.240.461
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.461
3ambVX6cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
3hyoADPPyridoxal kinase/0.461
3l8p0CEAngiopoietin-1 receptor2.7.10.10.461
3qtzX42Cyclin-dependent kinase 22.7.11.220.461
3zep1NXTyrosine-protein kinase JAK32.7.10.20.461
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4bcqTJFCyclin-dependent kinase 22.7.11.220.461
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4fks46KCyclin-dependent kinase 22.7.11.220.461
4fkt48KCyclin-dependent kinase 22.7.11.220.461
4fkv61KCyclin-dependent kinase 22.7.11.220.461
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.461
1ke6LS2Cyclin-dependent kinase 22.7.11.220.460
1oi9N20Cyclin-dependent kinase 22.7.11.220.460
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.460
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.460
2x6dX6DAurora kinase A2.7.11.10.460
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.460
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.460
3my5RFZCyclin-dependent kinase 22.7.11.220.460
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.460
3v8t477Tyrosine-protein kinase ITK/TSK2.7.10.20.460
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.460
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.460
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1gij2PUCyclin-dependent kinase 22.7.11.220.459
1om1IQACasein kinase II subunit alpha2.7.11.10.459
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.459
1q8yADPSerine/threonine-protein kinase SKY12.7.11.10.459
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
1u4dDBQActivated CDC42 kinase 1/0.459
1yvj4STTyrosine-protein kinase JAK32.7.10.20.459
2eufLQQCyclin-dependent kinase 62.7.11.220.459
2gjnFMNNitronate monooxygenase1.13.12.160.459
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.459
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.459
2yaaATPDeath-associated protein kinase 2/0.459
3fz1B98Cyclin-dependent kinase 22.7.11.220.459
3h6vNS6Glutamate receptor 2/0.459
3ixp834Ecdysone receptor/0.459
3kduNKSPeroxisome proliferator-activated receptor alpha/0.459
3lctADPALK tyrosine kinase receptor2.7.10.10.459
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.459
3oadLPORenin3.4.23.150.459
3qtuX44Cyclin-dependent kinase 22.7.11.220.459
3rm719ZCyclin-dependent kinase 22.7.11.220.459
4c62XWWTyrosine-protein kinase JAK2/0.459
4erwSTUCyclin-dependent kinase 22.7.11.220.459
4feq0T8Tyrosine-protein kinase receptor TYRO32.7.10.10.459
4rrrA3TThreonine--tRNA ligase6.1.1.30.459
4wsqKSAAP2-associated protein kinase 12.7.11.10.459
1oirHDYCyclin-dependent kinase 22.7.11.220.458
2bujSTUSerine/threonine-protein kinase 16/0.458
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.458
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
3c4zADPRhodopsin kinase/0.458
3c50ADPRhodopsin kinase/0.458
3gxlQIGTGF-beta receptor type-12.7.11.300.458
3h3t16HCollagen type IV alpha-3-binding protein/0.458
3kb1ADPIron-sulfur cluster carrier protein/0.458
3pj8404Cyclin-dependent kinase 22.7.11.220.458
3r6xX84Cyclin-dependent kinase 22.7.11.220.458
3rmf20ZCyclin-dependent kinase 22.7.11.220.458
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.458
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.458
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.458
1j39UPGDNA beta-glucosyltransferase/0.457
1ke9LS5Cyclin-dependent kinase 22.7.11.220.457
1kkq471Peroxisome proliferator-activated receptor alpha/0.457
1vyw292Cyclin-dependent kinase 22.7.11.220.457
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
2z2w770Wee1-like protein kinase2.7.10.20.457
3amaSKEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
3c0i3AMPeripheral plasma membrane protein CASK2.7.11.10.457
3emg685Tyrosine-protein kinase SYK2.7.10.20.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3ql8X01Cyclin-dependent kinase 22.7.11.220.457
3qxoX65Cyclin-dependent kinase 22.7.11.220.457
3tscNADUncharacterized protein/0.457
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.457
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.457
5e8ySTUTGF-beta receptor type-22.7.11.300.457
1k6cMK1Gag-Pol polyprotein3.4.23.160.456
1ke7LS3Cyclin-dependent kinase 22.7.11.220.456
1ol5ADPAurora kinase A2.7.11.10.456
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.456
2py3ACPFibroblast growth factor receptor 2/0.456
2vwqNAPGlucose 1-dehydrogenase/0.456
2xmyCDKCyclin-dependent kinase 22.7.11.220.456
2zdt46CMitogen-activated protein kinase 102.7.11.240.456
3cgbCOACoenzyme A disulfide reductase/0.456
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.260.456
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.456
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.456
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.456
3rk708ZCyclin-dependent kinase 22.7.11.220.456
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.456
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.456
4ez50RSCyclin-dependent kinase 62.7.11.220.456
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4gu94GUFocal adhesion kinase 12.7.10.20.456
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.456
4kbk1QGCasein kinase I isoform delta2.7.11.10.456
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.456
1cqp803Integrin alpha-L/0.455
1nvtNAPShikimate dehydrogenase (NADP(+))/0.455
1pmn984Mitogen-activated protein kinase 102.7.11.240.455
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.455
2in6839Wee1-like protein kinase2.7.10.20.455
2vu3LZECyclin-dependent kinase 22.7.11.220.455
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.455
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.455
3axwTIDCasein kinase II subunit alpha2.7.11.10.455
3b9lAZZSerum albumin/0.455
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.455
3kvxFMYMitogen-activated protein kinase 102.7.11.240.455
3q9wEMOCasein kinase II subunit alpha2.7.11.10.455
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
3qu0X40Cyclin-dependent kinase 22.7.11.220.455
3rk507ZCyclin-dependent kinase 22.7.11.220.455
4aguD15Cyclin-dependent kinase-like 1/0.455
4bcpT3CCyclin-dependent kinase 22.7.11.220.455
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4mf129YTyrosine-protein kinase ITK/TSK2.7.10.20.455
1phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.454
1u54ACPActivated CDC42 kinase 1/0.454
1v0oINRCell division control protein 2 homolog2.7.11.220.454
2gjlFMNNitronate monooxygenase1.13.12.160.454
2of4979Tyrosine-protein kinase Lck2.7.10.20.454
2pmlANPUncharacterized protein/0.454
2xk9XK9Serine/threonine-protein kinase Chk22.7.11.10.454
2xs0ANPMitogen-activated protein kinase 82.7.11.240.454
2yn8STUEphrin type-B receptor 42.7.10.10.454
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.454
3gu5ANPDeath-associated protein kinase 12.7.11.10.454
3ral04ZCyclin-dependent kinase 22.7.11.220.454
3rk909ZCyclin-dependent kinase 22.7.11.220.454
3rvg17PTyrosine-protein kinase JAK2/0.454
3t3c017Gag-Pol polyprotein3.4.23.160.454
4bddZ0OSerine/threonine-protein kinase Chk22.7.11.10.454
4bgh3I6Cyclin-dependent kinase 22.7.11.220.454
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.454
4iwd1JCHepatocyte growth factor receptor2.7.10.10.454
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.454
1bsvNDPGDP-L-fucose synthase/0.453
1dm2HMDCyclin-dependent kinase 22.7.11.220.453
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.453
1pjkANPCasein kinase II subunit alpha2.7.11.10.453
1pyePM1Cyclin-dependent kinase 22.7.11.220.453
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.453
2izt23DCasein kinase I isoform gamma-32.7.11.10.453
2om9AJAPeroxisome proliferator-activated receptor gamma/0.453
2r3lSCWCyclin-dependent kinase 22.7.11.220.453
2r3p3SCCyclin-dependent kinase 22.7.11.220.453
2vv9IM9Cyclin-dependent kinase 22.7.11.220.453
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
3c4wATPRhodopsin kinase/0.453
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.453
3lltANPProtein serine/threonine kinase-1/0.453
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.453
3qt62P0Mevalonate diphosphate decarboxylase/0.453
3qx2X63Cyclin-dependent kinase 22.7.11.220.453
3r8lZ30Cyclin-dependent kinase 22.7.11.220.453
3rjc06ZCyclin-dependent kinase 22.7.11.220.453
3uixQ17Serine/threonine-protein kinase pim-12.7.11.10.453
3v3vMYUMitogen-activated protein kinase 82.7.11.240.453
4bcmT7ZCyclin-dependent kinase 22.7.11.220.453
4ez30S0Cyclin-dependent kinase 22.7.11.220.453
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4fv7E94Mitogen-activated protein kinase 12.7.11.240.453
4nka2K7Fibroblast growth factor receptor 1/0.453
5e92ANPTGF-beta receptor type-22.7.11.300.453
1ckpPVBCyclin-dependent kinase 22.7.11.220.452
1eh4IC1Casein kinase I homolog 12.7.11.10.452
1ke5LS1Cyclin-dependent kinase 22.7.11.220.452
1lf2R37Plasmepsin-23.4.23.390.452
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.452
2ev9NAPShikimate dehydrogenase (NADP(+))/0.452
2rh9IGPTryptophan synthase alpha chain/0.452
2v7a627Tyrosine-protein kinase ABL12.7.10.20.452
3a7jADPSerine/threonine-protein kinase 242.7.11.10.452
3d4pNADL-lactate dehydrogenase 11.1.1.270.452
3fklFKLMitogen-activated protein kinase 14/0.452
3ig7EFPCyclin-dependent kinase 22.7.11.220.452
3kp4MIITranscriptional regulator TcaR/0.452
3lfsA07Cyclin-dependent kinase 22.7.11.220.452
3mdmFJZCholesterol 24-hydroxylase/0.452
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.452
3r7uX96Cyclin-dependent kinase 22.7.11.220.452
3ttjJBIMitogen-activated protein kinase 102.7.11.240.452
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.452
4g170VNCasein kinase I isoform gamma-32.7.11.10.452
4ic7ANPMitogen-activated protein kinase 72.7.11.240.452
1dhiMTXDihydrofolate reductase1.5.1.30.451
1m2rMNYCasein kinase II subunit alpha2.7.11.10.451
1vjy460TGF-beta receptor type-12.7.11.300.451
2a8xFADDihydrolipoyl dehydrogenase1.8.1.40.451
2fj1CTCTetracycline repressor protein class D/0.451
2oapANPType II secretion system protein (GspE-2)/0.451
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.451
2vtjLZ4Cyclin-dependent kinase 22.7.11.220.451
2xrwANPMitogen-activated protein kinase 82.7.11.240.451
3dt1P40Mitogen-activated protein kinase 14/0.451
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.451
3in6FMNUncharacterized protein/0.451
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.451
3lqfNADGalactitol dehydrogenase/0.451
3r83Z14Cyclin-dependent kinase 22.7.11.220.451
3slz3TLPutative gag-pro-pol polyprotein/0.451
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.451
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.451
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4fkg4CKCyclin-dependent kinase 22.7.11.220.451
4i4e1BQFocal adhesion kinase 12.7.10.20.451
4ipeANPTNF receptor-associated protein 1/0.451
4ix6ADPUncharacterized protein/0.451
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.451
1ay0TPPTransketolase 12.2.1.10.450
1fwkADPHomoserine kinase2.7.1.390.450
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1me6IVSPlasmepsin-23.4.23.390.450
1xe65FPPlasmepsin-23.4.23.390.450
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.450
2w17I19Cyclin-dependent kinase 22.7.11.220.450
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.450
3elySAHMethyltransferase/0.450
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.450
3il1B5DGlutamate receptor 2/0.450
3qwkX62Cyclin-dependent kinase 22.7.11.220.450
3s2pPMUCyclin-dependent kinase 22.7.11.220.450
3sdkP3NProteasome subunit beta type-53.4.25.10.450
3sdkP3NProteasome subunit beta type-63.4.25.10.450
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.450
4dymIYZActivin receptor type-12.7.11.300.450
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.450
4grb0XGCasein kinase II subunit alpha2.7.11.10.450
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.450
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.450
4loqSB4Mitogen-activated protein kinase 14/0.450
4qnaX11Serine/threonine-protein kinase 242.7.11.10.450
4qo9627Serine/threonine-protein kinase 242.7.11.10.450
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.450
4xwtU5PRibonuclease J/0.450
5auzGENDeath-associated protein kinase 12.7.11.10.450
6cp4CAMCamphor 5-monooxygenase1.14.15.10.450
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
1gz8MBPCyclin-dependent kinase 22.7.11.220.449
1h74ADPHomoserine kinase2.7.1.390.449
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.449
1m78NDPDihydrofolate reductase1.5.1.30.449
2chlDKICasein kinase I isoform gamma-32.7.11.10.449
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.449
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.449
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.449
2oji33AMitogen-activated protein kinase 12.7.11.240.449
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.449
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.449
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.449
3b2tM33Fibroblast growth factor receptor 2/0.449
3dd125DGlycogen phosphorylase, liver form2.4.1.10.449
3r1qX75Cyclin-dependent kinase 22.7.11.220.449
4acm7YGCyclin-dependent kinase 22.7.11.220.449
4c61LMMTyrosine-protein kinase JAK2/0.449
4eu8COASuccinyl-CoA:acetate CoA-transferase/0.449
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.449
4iarERM5-hydroxytryptamine receptor 1B/0.449
4lopSB4Mitogen-activated protein kinase 14/0.449
4q71FADBifunctional protein PutA/0.449
4qmlANPSerine/threonine-protein kinase 242.7.11.10.449
4wkqIREEpidermal growth factor receptor2.7.10.10.449
4yryFADGlutamate synthase, beta subunit/0.449
1di8DTQCyclin-dependent kinase 22.7.11.220.448
1ja0NAPNADPH--cytochrome P450 reductase/0.448
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.448
1zz2B11Mitogen-activated protein kinase 14/0.448
2btsU32Cyclin-dependent kinase 22.7.11.220.448
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.448
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.448
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.448
2vwx7X4Ephrin type-B receptor 42.7.10.10.448
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.448
2z3uCRRCytochrome P450/0.448
2znnS44Peroxisome proliferator-activated receptor alpha/0.448
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.448
3vt5YI2Vitamin D3 receptor/0.448
4an4DUDPutative glycosyl transferase/0.448
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.448
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.448
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.448
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
5a9sNAPPutative dehydrogenase/0.448
1bxqPP8Penicillopepsin-13.4.23.200.447
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.447
2i0y5CNMacrophage colony-stimulating factor 1 receptor2.7.10.10.447
2vttLZDCyclin-dependent kinase 22.7.11.220.447
2xlrFADPutative flavin-containing monooxygenase/0.447
2zdu446Mitogen-activated protein kinase 102.7.11.240.447
3efwAK8Aurora kinase A2.7.11.10.447
3r9uFADThioredoxin reductase/0.447
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.447
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.447
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.447
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.447
4dgmAGICasein kinase II subunit alpha2.7.11.10.447
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.447
4ek610KCyclin-dependent kinase 22.7.11.220.447
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.447
4hnf16WCasein kinase I isoform delta2.7.11.10.447
4hvi19STyrosine-protein kinase JAK32.7.10.20.447
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.446
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.446
1ppm0P1Penicillopepsin-13.4.23.200.446
1qy5NECEndoplasmin/0.446
1rx1NAPDihydrofolate reductase1.5.1.30.446
1tj0FADBifunctional protein PutA1.5.5.20.446
1u3dFADCryptochrome-1/0.446
1vyzN5BCyclin-dependent kinase 22.7.11.220.446
1xddAAYIntegrin alpha-L/0.446
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.446
2pckSAHDiphthine synthase/0.446
2pvhP19Casein kinase II subunit alpha2.7.11.10.446
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.446
2xiyXIYSerine/threonine-protein kinase pim-12.7.11.10.446
3frqERYErythromycin resistance repressor protein/0.446
3h3r14HCollagen type IV alpha-3-binding protein/0.446
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.446
3lfnA27Cyclin-dependent kinase 22.7.11.220.446
3qxpX64Cyclin-dependent kinase 22.7.11.220.446
3roy22ZCyclin-dependent kinase 22.7.11.220.446
3sw418KCyclin-dependent kinase 22.7.11.220.446
3zuyTCHTransporter/0.446
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.446
4kz01UJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
4o0sADNAurora kinase A2.7.11.10.446
5fwnNAPPutative dehydrogenase/0.446
1i6xCMPcAMP-activated global transcriptional regulator CRP/0.445
1tehNADAlcohol dehydrogenase class-31.1.1.10.445
1w0xOLOCyclin-dependent kinase 22.7.11.220.445
2d8aNADL-threonine 3-dehydrogenase/0.445
2fvdLIACyclin-dependent kinase 22.7.11.220.445
2xneASHAurora kinase A2.7.11.10.445
2y0mACOHistone acetyltransferase KAT8/0.445
3cisATPUniversal stress protein Rv2623/0.445
3ezrEZRCyclin-dependent kinase 22.7.11.220.445
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.445
3inmNDPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.445
3r1sX73Cyclin-dependent kinase 22.7.11.220.445
3sqq99ZCyclin-dependent kinase 22.7.11.220.445
4bcoT6QCyclin-dependent kinase 22.7.11.220.445
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.445
4gd40WSLysine-specific demethylase 4A1.14.110.445
4hgt15GCasein kinase I isoform delta2.7.11.10.445
4i02CMPcAMP-activated global transcriptional regulator CRP/0.445
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.445
1dhrNADDihydropteridine reductase1.5.1.340.444
1dz8CAMCamphor 5-monooxygenase1.14.15.10.444
1fmjRTLRetinol dehydratase/0.444
1jpaANPEphrin type-B receptor 22.7.10.10.444
1kzjCB3Thymidylate synthase/0.444
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.444
1llqNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.444
1psa0ZLPepsin A3.4.23.10.444
1rekB8LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.444
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.444
2a0cCK9Cyclin-dependent kinase 22.7.11.220.444
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.444
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2j2pSC2Ficolin-2/0.444
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.444
2q59240Peroxisome proliferator-activated receptor gamma/0.444
2xb7GUIALK tyrosine kinase receptor2.7.10.10.444
2xnbY8LCyclin-dependent kinase 22.7.11.220.444
3d2rADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial2.7.11.20.444
3d7tSTUTyrosine-protein kinase CSK/0.444
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.444
3oriAGSSerine/threonine protein kinase/0.444
3pe6ZYHMonoglyceride lipase/0.444
3pvuQRWBeta-adrenergic receptor kinase 12.7.11.150.444
3qlrNDPDihydrofolate reductase1.5.1.30.444
3qrtX14Cyclin-dependent kinase 22.7.11.220.444
3qzhX69Cyclin-dependent kinase 22.7.11.220.444
3r9oZ71Cyclin-dependent kinase 22.7.11.220.444
3u8w09JMitogen-activated protein kinase 14/0.444
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.444
4aotGW8Serine/threonine-protein kinase 102.7.11.10.444
4bis8HQLysine-specific demethylase 4A1.14.110.444
4ead0NPThymidine phosphorylase2.4.2.40.444
4fkq42KCyclin-dependent kinase 22.7.11.220.444
4h3qANPMitogen-activated protein kinase 12.7.11.240.444
4nks2M2Fibroblast growth factor receptor 1/0.444
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.444
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.444
4ux9ANPMitogen-activated protein kinase 82.7.11.240.444
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.444
5dr6SKEAurora kinase A2.7.11.10.444
1i59ANPChemotaxis protein CheA2.7.13.30.443
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.443
1t88CAMCamphor 5-monooxygenase1.14.15.10.443
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
2izrBRKCasein kinase I isoform gamma-32.7.11.10.443
3at4CCKCasein kinase II subunit alpha2.7.11.10.443
3gfbNADL-threonine 3-dehydrogenase/0.443
3imgBZ3Pantothenate synthetase6.3.2.10.443
3l9lL9LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3nizADPCdc2-like CDK2/CDC28 like protein kinase/0.443
3oibFDAPutative acyl-CoA dehydrogenase/0.443
3qtqX35Cyclin-dependent kinase 22.7.11.220.443
3s1h56ZCyclin-dependent kinase 22.7.11.220.443
3sm2478Putative gag-pro-pol polyprotein/0.443
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.443
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.443
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.443
4c9oCAMCytochrome P450/0.443
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.443
4ek816KCyclin-dependent kinase 22.7.11.220.443
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.443
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.443
4wq4ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
4xx0COASuccinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial6.2.1.40.443
1gqtACPRibokinase/0.442
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.442
1pjcNADAlanine dehydrogenase/0.442
1tqmANPRIO-type serine/threonine-protein kinase Rio22.7.11.10.442
1w6hTITPlasmepsin-23.4.23.390.442
2b9jADPMitogen-activated protein kinase FUS32.7.11.240.442
2bfyH1NAurora kinase B-A2.7.11.10.442
2cmwOLPCasein kinase I isoform gamma-12.7.11.10.442
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.442
3be9P04Casein kinase II subunit alpha2.7.11.10.442
3cgoJNOMitogen-activated protein kinase 102.7.11.240.442
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.442
3h18PMSEsterase/lipase/0.442
3h4vNAPPteridine reductase 11.5.1.330.442
3nr4PYVAbscisic acid receptor PYL2/0.442
3otwCOAPhosphopantetheine adenylyltransferase/0.442
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.442
4f640S8Fibroblast growth factor receptor 1/0.442
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
4fv9E71Mitogen-activated protein kinase 12.7.11.240.442
4g2rH1LProbable propionyl-CoA carboxylase beta chain 66.4.1.30.442
4ivb1J5Tyrosine-protein kinase JAK1/0.442
5cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1c1dNAIPhenylalanine dehydrogenase/0.441
1db1VDXVitamin D3 receptor/0.441
1dz6CAMCamphor 5-monooxygenase1.14.15.10.441
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1ie9VDXVitamin D3 receptor/0.441
1ir3ANPInsulin receptor2.7.10.10.441
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
1ol6ATPAurora kinase A2.7.11.10.441
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2ejvNADL-threonine 3-dehydrogenase/0.441
2ou2ACOHistone acetyltransferase KAT5/0.441
2pobGW4Peroxisome proliferator-activated receptor gamma/0.441
2vkeTACTetracycline repressor protein class D/0.441
2xa4AZ5Tyrosine-protein kinase JAK2/0.441
2yecXQ0Heat shock protein HSP 90-alpha/0.441
3l9hEMQKinesin-like protein KIF11/0.441
3mvl38PMitogen-activated protein kinase 14/0.441
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.441
3pdqKC6Lysine-specific demethylase 4A1.14.110.441
3q43D66M1 family aminopeptidase3.4.110.441
3rvhHQ2Lysine-specific demethylase 4A1.14.110.441
3sp9IL2Peroxisome proliferator-activated receptor delta/0.441
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.441
4a6bQG8Gag-Pol polyprotein3.4.23.160.441
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.441
4c9pCAMCytochrome P450/0.441
4ejmNAPPutative zinc-binding dehydrogenase/0.441
4fkr45KCyclin-dependent kinase 22.7.11.220.441
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.441
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.441
4q73FADBifunctional protein PutA/0.441
4u7wNDPMxaA/0.441
5cvcPLPSerine racemase/0.441
1gii1PUCyclin-dependent kinase 22.7.11.220.440
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.440
1kfbIGPTryptophan synthase alpha chain/0.440
1m9rINENitric oxide synthase, endothelial1.14.13.390.440
1p0hACOMycothiol acetyltransferase2.3.1.1890.440
1q1rFADPutidaredoxin reductase1.18.1.50.440
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.440
1t87CAMCamphor 5-monooxygenase1.14.15.10.440
1tqpATPRIO-type serine/threonine-protein kinase Rio22.7.11.10.440
1yc34BCHeat shock protein HSP 90-alpha/0.440
1ykdCMPAdenylate cyclase/0.440
2cig1DGDihydrofolate reductase1.5.1.30.440
2cy0NAPShikimate dehydrogenase (NADP(+))/0.440
2etm7PYFocal adhesion kinase 12.7.10.20.440
2huvSAHDiphthine synthase/0.440
2o0uC0MMitogen-activated protein kinase 102.7.11.240.440
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.440
2vgoAD5Aurora kinase B-A2.7.11.10.440
2x2mX2MProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.440
3ctyFADProbable thioredoxin reductase/0.440
3cyw017Gag-Pol polyprotein3.4.23.160.440
3fln3FNMitogen-activated protein kinase 14/0.440
3h86AP5Adenylate kinase/0.440
3p62FMNPentaerythritol tetranitrate reductase/0.440
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.440
3r7yZ04Cyclin-dependent kinase 22.7.11.220.440
3rak03ZCyclin-dependent kinase 22.7.11.220.440
3te4ACODopamine N-acetyltransferase/0.440
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
3umw596Serine/threonine-protein kinase pim-12.7.11.10.440
3w32W32Epidermal growth factor receptor2.7.10.10.440
3w551FMMitogen-activated protein kinase 12.7.11.240.440
4a32MYAGlycylpeptide N-tetradecanoyltransferase/0.440
4a84DXCMajor pollen allergen Bet v 1-A/0.440
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.440
4f650S9Fibroblast growth factor receptor 1/0.440
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.440
4i22IREEpidermal growth factor receptor2.7.10.10.440
4ivc1J6Tyrosine-protein kinase JAK1/0.440
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.440
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4looSB4Mitogen-activated protein kinase 14/0.440
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.440
4xiwAZMCarbonic anhydrase, alpha type/0.440
5bsgNAPPyrroline-5-carboxylate reductase/0.440