sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1ual | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1ual | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 1.000 | |
| 1uam | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.661 | |
| 1uak | SAM | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.634 | |
| 1p9p | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.619 | |
| 4mcd | 22L | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.598 | |
| 4yvj | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.562 | |
| 4yvh | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.549 | |
| 4yvg | SAM | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.532 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.510 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.510 | |
| 3n4k | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.508 | |
| 4h3y | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.507 | |
| 2z0y | SAM | Ribosomal RNA small subunit methyltransferase E | / | 0.505 | |
| 4ig6 | SAH | tRNA (guanine-N(1)-)-methyltransferase | / | 0.504 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.501 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.501 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.491 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.489 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.489 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.488 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.488 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.486 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.485 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.484 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.484 | |
| 2j2p | SC2 | Ficolin-2 | / | 0.484 | |
| 4pzk | SAH | Putative tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.482 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.480 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.480 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.479 | |
| 3bbd | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | 2.1.1 | 0.479 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.479 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.478 | |
| 3etg | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.478 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.477 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.476 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.476 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.476 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.476 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.476 | |
| 1iqg | XME | Coagulation factor X | 3.4.21.6 | 0.475 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.474 | |
| 4fue | 7UP | Urokinase-type plasminogen activator | 3.4.21.73 | 0.474 | |
| 1c1d | NAI | Phenylalanine dehydrogenase | / | 0.473 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.473 | |
| 3vas | ADN | Putative adenosine kinase | / | 0.473 | |
| 4fuj | 1U9 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.473 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.472 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.472 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.472 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.472 | |
| 3r96 | ACO | MccE protein | / | 0.472 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.471 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.471 | |
| 3lqs | PSZ | D-alanine aminotransferase | 2.6.1.21 | 0.471 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.471 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.470 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.470 | |
| 2cx8 | SAH | Ribosomal RNA small subunit methyltransferase E | / | 0.470 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.470 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.470 | |
| 4pne | SAH | Methyltransferase-like protein | / | 0.470 | |
| 4u0m | ATP | Cyclic GMP-AMP synthase | / | 0.470 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.470 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.469 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.469 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.469 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.469 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.469 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.469 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.469 | |
| 4nd4 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.469 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.469 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.468 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.468 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.468 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.468 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.468 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.468 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.468 | |
| 4blr | UTP | NTPase P4 | / | 0.468 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.468 | |
| 1qf5 | RPL | Adenylosuccinate synthetase | / | 0.467 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.467 | |
| 4kqw | NAP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.467 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.466 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.466 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.466 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.466 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.466 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.466 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.466 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.466 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.465 | |
| 2huq | SAH | Diphthine synthase | / | 0.465 | |
| 2z6r | SAH | Diphthine synthase | / | 0.465 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.465 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 4c04 | SFG | Protein arginine N-methyltransferase 6 | / | 0.465 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.464 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.464 | |
| 1tww | HH2 | Dihydropteroate synthase | / | 0.464 | |
| 2af3 | COA | Phosphate acetyltransferase | 2.3.1.8 | 0.464 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.464 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.464 | |
| 3qrw | NDP | Putative ketoacyl reductase | 1.3.1 | 0.464 | |
| 4a61 | ANP | Plasmid segregation protein ParM | / | 0.464 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.464 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 4x3m | ADN | RNA 2'-O ribose methyltransferase | / | 0.464 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.463 | |
| 1bw9 | NAD | Phenylalanine dehydrogenase | / | 0.463 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.463 | |
| 4jwh | SAH | tRNA (guanine(9)-N1)-methyltransferase | / | 0.463 | |
| 4k28 | NAD | Shikimate dehydrogenase family protein | / | 0.463 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.463 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.462 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.462 | |
| 3lm9 | ADP | Putative fructokinase | 2.7.1.4 | 0.462 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.462 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.462 | |
| 4mcc | 21X | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.462 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.462 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.462 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.462 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.461 | |
| 1nfy | RTR | Coagulation factor X | 3.4.21.6 | 0.461 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.461 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.461 | |
| 3r3s | NAD | Putative oxidoreductase | / | 0.461 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.461 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.460 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.460 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.460 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.460 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.460 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.460 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.460 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.460 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.459 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.459 | |
| 2aa3 | AP0 | L-lactate dehydrogenase | / | 0.459 | |
| 2ejz | SAH | Diphthine synthase | / | 0.459 | |
| 2emr | SAH | Diphthine synthase | / | 0.459 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.459 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.459 | |
| 3a28 | NAD | L-2,3-butanediol dehydrogenase | 1.1.1.76 | 0.459 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.459 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.459 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.459 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.459 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.459 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.459 | |
| 1f0y | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.458 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.458 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 1vja | 7IN | Urokinase-type plasminogen activator | 3.4.21.73 | 0.458 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.458 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.458 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.458 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.458 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.458 | |
| 4kgn | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.458 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.458 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.457 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.457 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.457 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.457 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.457 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.456 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.456 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.456 | |
| 1owk | 303 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.456 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.456 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.456 | |
| 2ehl | SAH | Diphthine synthase | / | 0.456 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.456 | |
| 2pca | SAH | Diphthine synthase | / | 0.456 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.456 | |
| 3w4y | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.456 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.456 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.456 | |
| 5a3b | APR | SIR2 family protein | / | 0.456 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.455 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.455 | |
| 2hrb | NAP | Carbonyl reductase [NADPH] 3 | 1.1.1.184 | 0.455 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.455 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3gnw | XNC | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.455 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.455 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.455 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.455 | |
| 4ekg | 0QJ | Histone-lysine N-methyltransferase, H3 lysine-79 specific | 2.1.1.43 | 0.455 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.455 | |
| 5cvc | PLP | Serine racemase | / | 0.455 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.454 | |
| 1dli | UDX | UDP-glucose 6-dehydrogenase | / | 0.454 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1n7h | NDP | GDP-mannose 4,6 dehydratase 2 | 4.2.1.47 | 0.454 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.454 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.454 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.454 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.454 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.454 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.454 | |
| 2z4y | 252 | Geranylgeranyl pyrophosphate synthase | / | 0.454 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.454 | |
| 3khu | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.454 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.454 | |
| 3nug | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.454 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.454 | |
| 4e2b | FMN | Dehydrogenase | / | 0.454 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.454 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.454 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.454 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.454 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.453 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1re7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.453 | |
| 2a7r | 5GP | GMP reductase 2 | / | 0.453 | |
| 2e8h | SAH | Diphthine synthase | / | 0.453 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.453 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.453 | |
| 3ing | NDP | Homoserine dehydrogenase related protein | / | 0.453 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.453 | |
| 3kjm | 245 | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.453 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.453 | |
| 4dxl | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.453 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.452 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.452 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1m75 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.452 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.452 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.452 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.452 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.452 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.452 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.452 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.452 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.452 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.452 | |
| 5cyo | GDP | Septin-9 | / | 0.452 | |
| 1ep1 | FMN | Dihydroorotate dehydrogenase B (NAD(+)), catalytic subunit | 1.3.1.14 | 0.451 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.451 | |
| 1l4k | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.451 | |
| 1u3d | FAD | Cryptochrome-1 | / | 0.451 | |
| 1wnt | NAP | L-xylulose reductase | 1.1.1.10 | 0.451 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.451 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.451 | |
| 2emu | SAH | Diphthine synthase | / | 0.451 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.451 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.451 | |
| 2po3 | T4K | 4-dehydrase | / | 0.451 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.451 | |
| 4bkq | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.451 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.450 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.450 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.450 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.450 | |
| 1u4d | DBQ | Activated CDC42 kinase 1 | / | 0.450 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.450 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.450 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.450 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.450 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.450 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3ndc | SAH | Precorrin-4 C(11)-methyltransferase | 2.1.1.133 | 0.450 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.450 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.450 | |
| 3w23 | 3RO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.450 | |
| 4f4q | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.450 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 4kb8 | 1QO | Casein kinase I isoform delta | 2.7.11.1 | 0.450 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.450 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.450 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.450 | |
| 5lc1 | NAD | L-threonine 3-dehydrogenase | / | 0.450 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.449 | |
| 1ghv | 120 | Prothrombin | 3.4.21.5 | 0.449 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.449 | |
| 1q6t | 600 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.449 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.449 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.449 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.449 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.449 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.449 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.449 | |
| 3w1x | XRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.449 | |
| 4jal | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.449 | |
| 4l4x | NDP | AmphI | / | 0.449 | |
| 4m2b | UPG | UDP-glucose pyrophosphorylase | / | 0.449 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.448 | |
| 1q12 | ATP | Maltose/maltodextrin import ATP-binding protein MalK | / | 0.448 | |
| 1xjw | PAL | Aspartate carbamoyltransferase catalytic subunit | 2.1.3.2 | 0.448 | |
| 2e15 | SAH | Diphthine synthase | / | 0.448 | |
| 2g9r | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.448 | |
| 2pcm | SAH | Diphthine synthase | / | 0.448 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.448 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.448 | |
| 2yy8 | SAM | tRNA (cytidine(56)-2'-O)-methyltransferase | / | 0.448 | |
| 2zfr | 46U | Prothrombin | 3.4.21.5 | 0.448 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.448 | |
| 3a20 | FMN | FMN-binding protein | / | 0.448 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.448 | |
| 3elu | SAM | Methyltransferase | / | 0.448 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.448 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.448 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.448 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.448 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.448 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.448 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.448 | |
| 4xcz | FON | Qdtf | / | 0.448 | |
| 1gc5 | ADP | ADP-dependent glucokinase | 2.7.1.147 | 0.447 | |
| 1ikg | REX | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.447 | |
| 1j5p | NAD | L-aspartate dehydrogenase | 1.4.1.21 | 0.447 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.447 | |
| 2f4b | EHA | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2ktd | PUC | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.447 | |
| 2oc9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.447 | |
| 2v7g | NAD | Urocanate hydratase | 4.2.1.49 | 0.447 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.447 | |
| 3dhb | C6L | N-acyl homoserine lactonase AiiA | 3.1.1.81 | 0.447 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.447 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.447 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.447 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.447 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.447 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.447 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.447 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.447 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.447 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.447 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.447 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.446 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.446 | |
| 1j0x | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.446 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.446 | |
| 1m75 | CAA | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.446 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1mew | XMP | Inosine-5'-monophosphate dehydrogenase | / | 0.446 | |
| 1pjc | NAD | Alanine dehydrogenase | / | 0.446 | |
| 1qy5 | NEC | Endoplasmin | / | 0.446 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.446 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.446 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2jdt | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.446 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.446 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.446 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.446 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.446 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3h5u | H5U | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3h6v | NS6 | Glutamate receptor 2 | / | 0.446 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.446 | |
| 3i7v | B4P | AP4A hydrolase | / | 0.446 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.446 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.446 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.446 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3t70 | DU4 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.446 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.446 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.446 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.446 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.446 | |
| 4qxp | 1YE | Stimulator of interferon genes protein | / | 0.446 | |
| 4tlz | NAP | KtzI | / | 0.446 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.446 | |
| 4u7w | NDP | MxaA | / | 0.446 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.446 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.446 | |
| 1b15 | NAE | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.445 | |
| 1e80 | 0GQ | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 1qf4 | RPD | Adenylosuccinate synthetase | / | 0.445 | |
| 1qyv | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.445 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1sny | NAP | LD36273p | / | 0.445 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.445 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.445 | |
| 2e8q | SAH | Diphthine synthase | / | 0.445 | |
| 2eeq | SAH | Diphthine synthase | / | 0.445 | |
| 2gil | GTP | Ras-related protein Rab-6A | / | 0.445 | |
| 2nv4 | SAM | S-adenosyl-L-methionine-binding protein AF_0241 | / | 0.445 | |
| 2r8p | T6F | Transketolase 1 | / | 0.445 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.445 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.445 | |
| 3a3b | RBF | Lumazine protein | / | 0.445 | |
| 3a3g | DLZ | Lumazine protein | / | 0.445 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.445 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.445 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.445 | |
| 3i12 | ADP | D-alanine--D-alanine ligase A | 6.3.2.4 | 0.445 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.445 | |
| 4e5p | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.445 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.445 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.445 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.445 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.444 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.444 | |
| 1rc1 | KT3 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.444 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.444 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2cji | GSK | Coagulation factor X | 3.4.21.6 | 0.444 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.444 | |
| 2dsg | SAH | Diphthine synthase | / | 0.444 | |
| 2ek2 | SAH | Diphthine synthase | / | 0.444 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.444 | |
| 2owu | SAH | Diphthine synthase | / | 0.444 | |
| 2pch | SAH | Diphthine synthase | / | 0.444 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.444 | |
| 2xby | 63C | Coagulation factor X | 3.4.21.6 | 0.444 | |
| 2y5g | FJD | Coagulation factor X | 3.4.21.6 | 0.444 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.444 | |
| 3e39 | FMN | Nitroreductase | / | 0.444 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.444 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.444 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.444 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.444 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.444 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.444 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.444 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.444 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 1ta2 | 176 | Prothrombin | 3.4.21.5 | 0.443 | |
| 2aq7 | TL5 | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.443 | |
| 2hr8 | SAH | Diphthine synthase | / | 0.443 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2vwh | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.443 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.443 | |
| 3dzv | ADP | Hydroxyethylthiazole kinase | / | 0.443 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.443 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.443 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3zuy | TCH | Transporter | / | 0.443 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.443 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.443 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.443 | |
| 4y93 | 746 | Tyrosine-protein kinase | / | 0.443 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.443 | |
| 1byg | STU | Tyrosine-protein kinase CSK | / | 0.442 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.442 | |
| 1k7l | 544 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1nuq | NXX | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.442 | |
| 1ppj | ANY | Cytochrome b | / | 0.442 | |
| 1rbz | KT5 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.442 | |
| 1t2a | NDP | GDP-mannose 4,6 dehydratase | 4.2.1.47 | 0.442 | |
| 1uay | ADN | Oxidoreductase | / | 0.442 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.442 | |
| 2en5 | SAH | Diphthine synthase | / | 0.442 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.442 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.442 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.442 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.442 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.442 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3eku | CY9 | Actin-5C | / | 0.442 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3icp | NAD | NAD-dependent epimerase/dehydratase | / | 0.442 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.442 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.442 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.442 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.442 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.442 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.442 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.441 | |
| 1hon | GNH | Adenylosuccinate synthetase | / | 0.441 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.441 | |
| 1iy8 | NAD | Levodione reductase | / | 0.441 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.441 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.441 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.441 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.441 | |
| 2cgu | 3A3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ek4 | SAH | Diphthine synthase | / | 0.441 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.441 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.441 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.441 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.441 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.441 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.441 | |
| 3ko8 | NAD | NAD-dependent epimerase/dehydratase | / | 0.441 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.441 | |
| 3mje | NDP | AmphB | / | 0.441 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3q33 | ACO | Histone acetyltransferase RTT109 | 2.3.1.48 | 0.441 | |
| 3w2j | QRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.441 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 4a0r | DTB | Bifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial | 6.3.3.3 | 0.441 | |
| 4cnf | MTA | SpoU rRNA methylase | / | 0.441 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4ien | COA | Putative acyl-CoA hydrolase | / | 0.441 | |
| 4kos | 4KO | Uncharacterized protein | / | 0.441 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.441 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.441 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.441 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.441 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.440 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.440 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.440 | |
| 1v35 | NAI | Enoyl-ACP reductase | / | 0.440 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1w7i | ADP | Unconventional myosin-Va | / | 0.440 | |
| 2dv3 | SAH | Diphthine synthase | / | 0.440 | |
| 2hsd | NAD | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.440 | |
| 2j5b | TYE | Tyrosine--tRNA ligase | 6.1.1.1 | 0.440 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.440 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.440 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.440 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.440 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.440 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.440 | |
| 3m4p | 4AD | Asparaginyl-tRNA synthetase, putative | / | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3ndr | NAD | Pyridoxal 4-dehydrogenase | 1.1.1.107 | 0.440 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.440 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.440 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.440 | |
| 3p19 | NDP | Putative blue fluorescent protein | / | 0.440 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.440 | |
| 3w2l | VRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.440 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.440 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.440 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.440 | |
| 4wpu | GDP | Phosphoenolpyruvate carboxykinase [GTP] | / | 0.440 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.440 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 | |
| 5cns | CDP | Ribonucleoside-diphosphate reductase 1 subunit alpha | 1.17.4.1 | 0.440 |