sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 | 1.000 | |
| 2vj7 | VG6 | Beta-secretase 1 | 3.4.23.46 | 0.761 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.751 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.743 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.713 | |
| 2vj9 | VG7 | Beta-secretase 1 | 3.4.23.46 | 0.701 | |
| 2viz | VG4 | Beta-secretase 1 | 3.4.23.46 | 0.699 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.682 | |
| 2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 | 0.658 | |
| 2oah | QIN | Beta-secretase 1 | 3.4.23.46 | 0.648 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.635 | |
| 2vie | VG0 | Beta-secretase 1 | 3.4.23.46 | 0.629 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.618 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.616 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.610 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.607 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.600 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.590 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.589 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.587 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.578 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.577 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.574 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.572 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.568 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.562 | |
| 4i1c | 1BE | Beta-secretase 1 | 3.4.23.46 | 0.558 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.557 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.554 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.552 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.544 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.544 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.543 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.533 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.529 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.524 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.520 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.519 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.518 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.516 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.512 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.512 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.510 | |
| 1gvt | 2ZS | Endothiapepsin | 3.4.23.22 | 0.507 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.507 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.506 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.505 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.505 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.504 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.503 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.503 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.502 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.500 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.500 | |
| 1w51 | L01 | Beta-secretase 1 | 3.4.23.46 | 0.499 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.497 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.497 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.496 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.494 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.494 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.493 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.492 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.491 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.491 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.491 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.490 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.490 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.490 | |
| 4fs4 | H24 | Beta-secretase 1 | 3.4.23.46 | 0.490 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.489 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.489 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.488 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.488 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.488 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.487 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.487 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.486 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.486 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.485 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.485 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.484 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.483 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.483 | |
| 3qbh | QBH | Beta-secretase 1 | 3.4.23.46 | 0.483 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.483 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.482 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.482 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.482 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.481 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.481 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.481 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.481 | |
| 4y38 | 0A9 | Endothiapepsin | 3.4.23.22 | 0.481 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.480 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.480 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.479 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.478 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.478 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.478 | |
| 3ijo | B4D | Glutamate receptor 2 | / | 0.477 | |
| 4frs | 0V6 | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4ttc | FMN | Iodotyrosine deiodinase 1 | / | 0.477 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.476 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.476 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.475 | |
| 1ma0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.475 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.475 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.475 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.475 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.475 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.475 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.474 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.474 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.474 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.474 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.473 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.473 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.473 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.473 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.472 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.472 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.472 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.472 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.472 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.472 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.472 | |
| 1gvw | 0EM | Endothiapepsin | 3.4.23.22 | 0.471 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.471 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.471 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.471 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.470 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.470 | |
| 2qjo | NAD | Bifunctional NMN adenylyltransferase/Nudix hydrolase | 2.7.7.1 | 0.470 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.470 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.469 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.469 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.469 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.469 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.469 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.469 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.469 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.469 | |
| 4lxm | 1YU | Beta-secretase 1 | 3.4.23.46 | 0.469 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.469 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.468 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.468 | |
| 2emu | SAH | Diphthine synthase | / | 0.468 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.468 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.468 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.468 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.467 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.467 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.467 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.467 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.467 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.467 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.467 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.467 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.467 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.466 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.466 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.466 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.466 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.466 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.466 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.466 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.466 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.466 | |
| 1c7o | PPG | Hemolysin | / | 0.465 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.465 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.465 | |
| 2xx9 | 1NF | Glutamate receptor 2 | / | 0.465 | |
| 3ig6 | 438 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.465 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.465 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.465 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.465 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.464 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.464 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.464 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.464 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.464 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.464 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.464 | |
| 4usr | FAD | Monooxygenase | / | 0.464 | |
| 4ype | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.464 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.464 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.463 | |
| 2dsg | SAH | Diphthine synthase | / | 0.463 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.463 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.463 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.463 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.463 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.463 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.463 | |
| 3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 4blr | UTP | NTPase P4 | / | 0.463 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.463 | |
| 4yao | FMN | NADPH--cytochrome P450 reductase | / | 0.463 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.462 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.462 | |
| 1q6s | 214 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.462 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.462 | |
| 2hux | SAH | Diphthine synthase | / | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.462 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.462 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.462 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.461 | |
| 3d3x | ARG_ILE_MET_GLU_NH2 | Type E botulinum toxin | / | 0.461 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.461 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.461 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.461 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.461 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.460 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.460 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.460 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.460 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.460 | |
| 3eks | CY9 | Actin-5C | / | 0.460 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.460 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.460 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.460 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.460 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.459 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.459 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.459 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.459 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.459 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.459 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.459 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.459 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.458 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.458 | |
| 2ejz | SAH | Diphthine synthase | / | 0.458 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.458 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.458 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.458 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.458 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.458 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.458 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.458 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2en5 | SAH | Diphthine synthase | / | 0.457 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.457 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.457 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4c4o | NAD | SADH | / | 0.457 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.457 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.457 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.457 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.457 | |
| 1cg3 | IMO | Adenylosuccinate synthetase | / | 0.456 | |
| 1ds7 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.456 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.456 | |
| 1iy8 | NAD | Levodione reductase | / | 0.456 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.456 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.456 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 3ahn | 3A1 | Oligopeptidase | / | 0.456 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.456 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.456 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 3ieu | GDP | GTPase Era | / | 0.456 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.456 | |
| 3pb5 | F63 | Endothiapepsin | 3.4.23.22 | 0.456 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.456 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.456 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.456 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.456 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.456 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.455 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.455 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.455 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.455 | |
| 1g5q | ASP_SER_TYR_THR_CYS | Epidermin decarboxylase | 4.1.1 | 0.455 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.455 | |
| 1nai | NAD | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.455 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.455 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.455 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.455 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.455 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.455 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.455 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.455 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.455 | |
| 3kpb | SAM | Uncharacterized protein MJ0100 | / | 0.455 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.455 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.455 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.455 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.455 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.455 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.454 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.454 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.454 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.454 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.454 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.454 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.454 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.454 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.454 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.454 | |
| 4xr9 | NAD | CalS8 | / | 0.454 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.453 | |
| 2ag5 | NAD | 3-hydroxybutyrate dehydrogenase type 2 | / | 0.453 | |
| 2dgn | DOI | Adenylosuccinate synthetase isozyme 1 | / | 0.453 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.453 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.453 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.453 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.453 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.453 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.453 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.453 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.453 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.452 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.452 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.452 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.452 | |
| 2e8q | SAH | Diphthine synthase | / | 0.452 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.452 | |
| 2o8j | SAH | Histone-lysine N-methyltransferase EHMT2 | / | 0.452 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.452 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.452 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.452 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.452 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.452 | |
| 4yvz | 3AT | DNA integrity scanning protein DisA | / | 0.452 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.451 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 1xgi | NST | Beta-lactamase | 3.5.2.6 | 0.451 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.451 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.451 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.451 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.451 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.451 | |
| 5af7 | FAD | Acyl-CoA dehydrogenase | / | 0.451 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.451 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.450 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.450 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.450 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.450 | |
| 1orr | NAD | CDP-paratose 2-epimerase | / | 0.450 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.450 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.450 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.450 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.450 | |
| 2br5 | SAH | Cephalosporin hydroxylase CmcI | / | 0.450 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.450 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2fzw | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.450 | |
| 2p6l | SAH | Diphthine synthase | / | 0.450 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.450 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.450 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4ef8 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.450 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.450 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.450 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.450 | |
| 5f8e | SAH | Possible transcriptional regulatory protein | / | 0.450 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.449 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.449 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.449 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.449 | |
| 2bju | IH4 | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.449 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.449 | |
| 2e4n | SAH | Diphthine synthase | / | 0.449 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2eeq | SAH | Diphthine synthase | / | 0.449 | |
| 2emr | SAH | Diphthine synthase | / | 0.449 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.449 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.449 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.449 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.449 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.449 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3mp3 | HGG | Hydroxymethylglutaryl-CoA lyase, mitochondrial | 4.1.3.4 | 0.449 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.449 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.449 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.449 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.449 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.449 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.449 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.448 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.448 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 2p5f | SAH | Diphthine synthase | / | 0.448 | |
| 2q3e | NAI | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.448 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.448 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3iaa | TYD | CalG2 | / | 0.448 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.448 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.448 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.448 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.447 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.447 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1vl8 | NAP | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.447 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.447 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.447 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.447 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.447 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.447 | |
| 4xbo | SAH | tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | 2.1.1.200 | 0.447 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.447 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.446 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1o97 | FAD | Electron transfer flavoprotein subunit alpha | / | 0.446 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.446 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2e83 | FMN | FMN-binding protein | / | 0.446 | |
| 2hut | SAH | Diphthine synthase | / | 0.446 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.446 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.446 | |
| 3a3g | DLZ | Lumazine protein | / | 0.446 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.446 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.446 | |
| 3uce | NDP | Dehydrogenase | / | 0.446 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.446 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.446 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.446 | |
| 1cdo | NAD | Alcohol dehydrogenase 1 | 1.1.1.1 | 0.445 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.445 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.445 | |
| 1njb | UMP | Thymidylate synthase | / | 0.445 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.445 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.445 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.445 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.445 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.445 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.445 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.445 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.445 | |
| 2owk | SAH | Diphthine synthase | / | 0.445 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.445 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.445 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.445 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.445 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.445 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.445 | |
| 4oxy | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.445 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.445 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.445 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.444 | |
| 2e17 | SAH | Diphthine synthase | / | 0.444 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.444 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.444 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.444 | |
| 2y4g | TIR | TamL | / | 0.444 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.444 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.444 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 3nbv | ANP | Ketohexokinase | / | 0.444 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.444 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.444 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.444 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.444 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.444 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.444 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.443 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 1i6k | TYM | Tryptophan--tRNA ligase | 6.1.1.2 | 0.443 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.443 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.443 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.443 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.443 | |
| 1zrq | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.443 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.443 | |
| 2e07 | SAH | Diphthine synthase | / | 0.443 | |
| 2e16 | SAH | Diphthine synthase | / | 0.443 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.443 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.443 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.443 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.443 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4i6a | HMG | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.88 | 0.443 | |
| 4kwh | NAP | Reductase homolog | / | 0.443 | |
| 4lol | 1YE | Stimulator of interferon genes protein | / | 0.443 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.443 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.443 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.442 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.442 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.442 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.442 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.442 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3ruf | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.442 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4eud | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4kb9 | G79 | Protease | / | 0.442 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.442 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.442 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.442 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.441 | |
| 1eag | A70 | Candidapepsin-2 | 3.4.23.24 | 0.441 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.441 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.441 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.441 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.441 | |
| 1yki | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.441 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.441 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2dsh | SAH | Diphthine synthase | / | 0.441 | |
| 2p6d | SAH | Diphthine synthase | / | 0.441 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.441 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.441 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.441 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.441 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.441 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 4ji9 | 1M3 | Tyrosine-protein kinase JAK2 | / | 0.441 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.441 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.440 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 1e3l | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.440 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.440 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.440 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.440 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.440 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.440 | |
| 2dxv | SAH | Diphthine synthase | / | 0.440 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.440 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.440 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.440 | |
| 3e39 | FMN | Nitroreductase | / | 0.440 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.440 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.440 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.440 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.440 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.440 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.440 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.440 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.440 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.440 | |
| 3v2u | ATP | Protein GAL3 | / | 0.440 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.440 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.440 | |
| 4m87 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 4zju | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.440 | |
| 5ahs | FAD | Acyl-CoA dehydrogenase | / | 0.440 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 | |
| 5ftf | ADP | TPR domain protein | / | 0.440 |