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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1m7qDQOMitogen-activated protein kinase 14

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1m7qDQOMitogen-activated protein kinase 14/1.000
1ouk084Mitogen-activated protein kinase 14/0.645
1ouy094Mitogen-activated protein kinase 14/0.633
3gc7B45Mitogen-activated protein kinase 14/0.601
1ove358Mitogen-activated protein kinase 14/0.583
3zsh469Mitogen-activated protein kinase 14/0.582
1zyjBI5Mitogen-activated protein kinase 14/0.576
3fc152PMitogen-activated protein kinase 14/0.572
3fmn530Mitogen-activated protein kinase 14/0.571
3flyFLYMitogen-activated protein kinase 14/0.570
3fskRO6Mitogen-activated protein kinase 14/0.563
3hllI45Mitogen-activated protein kinase 14/0.563
3fmh533Mitogen-activated protein kinase 14/0.562
3iphG11Mitogen-activated protein kinase 14/0.561
3roc29AMitogen-activated protein kinase 14/0.561
3flsFLSMitogen-activated protein kinase 14/0.560
4nks2M2Fibroblast growth factor receptor 1/0.560
3fl4FL4Mitogen-activated protein kinase 14/0.558
3s4qNK0Mitogen-activated protein kinase 14/0.554
3kf7L9GMitogen-activated protein kinase 14/0.553
1ywrLI9Mitogen-activated protein kinase 14/0.552
3dt1P40Mitogen-activated protein kinase 14/0.552
3fi4FI4Mitogen-activated protein kinase 14/0.551
3fmlFMLMitogen-activated protein kinase 14/0.551
3fln3FNMitogen-activated protein kinase 14/0.550
3mvl38PMitogen-activated protein kinase 14/0.550
2zazGK1Mitogen-activated protein kinase 14/0.548
3hp552PMitogen-activated protein kinase 14/0.548
3gfeP37Mitogen-activated protein kinase 14/0.547
3ha85JZMitogen-activated protein kinase 14/0.545
1bl6SB6Mitogen-activated protein kinase 14/0.543
4looSB4Mitogen-activated protein kinase 14/0.540
2fgiPD1Fibroblast growth factor receptor 1/0.539
3uvp048Mitogen-activated protein kinase 14/0.539
2itqITQEpidermal growth factor receptor2.7.10.10.538
4f640S8Fibroblast growth factor receptor 1/0.537
3flwFLWMitogen-activated protein kinase 14/0.536
3hl7I47Mitogen-activated protein kinase 14/0.534
3nww3NWMitogen-activated protein kinase 14/0.534
4jrvKJVEpidermal growth factor receptor2.7.10.10.534
1yw2PGJMitogen-activated protein kinase 14/0.532
4lopSB4Mitogen-activated protein kinase 14/0.532
3obgSB2Mitogen-activated protein kinase 14/0.531
3flq891Mitogen-activated protein kinase 14/0.530
3flzFLZMitogen-activated protein kinase 14/0.530
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.530
3fkoFKOMitogen-activated protein kinase 14/0.529
3l8sBFFMitogen-activated protein kinase 14/0.529
4nka2K7Fibroblast growth factor receptor 1/0.529
2itzIREEpidermal growth factor receptor2.7.10.10.528
2qd9LGFMitogen-activated protein kinase 14/0.528
3mpaSB2Mitogen-activated protein kinase 14/0.528
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.528
4aa5NQBMitogen-activated protein kinase 14/0.527
3gc9B45Mitogen-activated protein kinase 112.7.11.240.523
4ewqMWLMitogen-activated protein kinase 14/0.522
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.521
3itzP66Mitogen-activated protein kinase 14/0.521
3hub469Mitogen-activated protein kinase 14/0.520
4j97ACPFibroblast growth factor receptor 2/0.520
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.519
3fknFKNMitogen-activated protein kinase 14/0.519
3uvqFS8Mitogen-activated protein kinase 14/0.517
3fmkFMKMitogen-activated protein kinase 14/0.516
4f630S7Fibroblast growth factor receptor 1/0.516
1bl7SB4Mitogen-activated protein kinase 14/0.515
2itpAEEEpidermal growth factor receptor2.7.10.10.515
3mpt1GKMitogen-activated protein kinase 14/0.514
1yqj6NPMitogen-activated protein kinase 14/0.513
2balPQAMitogen-activated protein kinase 14/0.513
2ghlLIBMitogen-activated protein kinase 14/0.513
2q0bACPFibroblast growth factor receptor 2/0.512
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.512
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.511
3fmmXI2Mitogen-activated protein kinase 14/0.510
3l8xN4DMitogen-activated protein kinase 14/0.510
4mcv29KProto-oncogene tyrosine-protein kinase Src2.7.10.20.510
4mxoDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.510
3fmjFMJMitogen-activated protein kinase 14/0.509
4bc6XZNSerine/threonine-protein kinase 102.7.11.10.509
1zzlTZYMitogen-activated protein kinase 14/0.508
3bv2P38Mitogen-activated protein kinase 14/0.508
4eh60ONMitogen-activated protein kinase 14/0.508
2zb0GK3Mitogen-activated protein kinase 14/0.507
3iw5DF3Mitogen-activated protein kinase 14/0.507
4aacAAVMitogen-activated protein kinase 14/0.507
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.506
1w84L12Mitogen-activated protein kinase 14/0.506
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.506
2ittAEEEpidermal growth factor receptor2.7.10.10.504
2xclANPPhosphoribosylamine--glycine ligase/0.504
4jr3KJREpidermal growth factor receptor2.7.10.10.504
4nk92K5Fibroblast growth factor receptor 1/0.504
2itwITQEpidermal growth factor receptor2.7.10.10.503
3w33W19Epidermal growth factor receptor2.7.10.10.503
4aa4QC0Mitogen-activated protein kinase 14/0.502
3js2VM1Fibroblast growth factor receptor 1/0.501
4loqSB4Mitogen-activated protein kinase 14/0.501
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.500
2rg5279Mitogen-activated protein kinase 14/0.500
3fsfFSSMitogen-activated protein kinase 14/0.500
4eh70OOMitogen-activated protein kinase 14/0.500
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.500
4jq7KJQEpidermal growth factor receptor2.7.10.10.499
2pvyACPFibroblast growth factor receptor 2/0.498
3uibSB2Putative mitogen-activated protein kinase/0.498
4ia1BIVVitamin D3 receptor A/0.498
2pwlACPFibroblast growth factor receptor 2/0.497
3hvcGG5Mitogen-activated protein kinase 14/0.497
1m17AQ4Epidermal growth factor receptor2.7.10.10.496
1zz2B11Mitogen-activated protein kinase 14/0.496
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.496
2py3ACPFibroblast growth factor receptor 2/0.496
4eh50OMMitogen-activated protein kinase 14/0.496
2i0ePDSProtein kinase C beta type2.7.11.130.495
2zm1KSFTyrosine-protein kinase Lck2.7.10.20.495
3fklFKLMitogen-activated protein kinase 14/0.495
4i231C9Epidermal growth factor receptor2.7.10.10.495
1oz1FPHMitogen-activated protein kinase 14/0.494
2ghmLICMitogen-activated protein kinase 14/0.494
2zybKSLTyrosine-protein kinase Lck2.7.10.20.494
3gubGUBDeath-associated protein kinase 12.7.11.10.494
4kin1M8Mitogen-activated protein kinase 14/0.494
2hk51BMTyrosine-protein kinase HCK2.7.10.20.493
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.493
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.492
3mvm39PMitogen-activated protein kinase 14/0.492
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.492
4lggVGGProto-oncogene tyrosine-protein kinase Src2.7.10.20.492
4nfn2KCTau-tubulin kinase 12.7.11.10.492
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.492
3u8w09JMitogen-activated protein kinase 14/0.491
3vjoANPEpidermal growth factor receptor2.7.10.10.491
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.489
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.489
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.489
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.489
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.488
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.488
2vzmNRBCytochrome P450 monooxygenase PikC/0.488
2y6o1N1Ephrin type-A receptor 42.7.10.10.488
3oafOAGDihydrofolate reductase1.5.1.30.488
5aacVGHALK tyrosine kinase receptor2.7.10.10.488
1finATPCyclin-dependent kinase 22.7.11.220.487
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.487
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.487
3bv3P39Mitogen-activated protein kinase 14/0.486
3bx5304Mitogen-activated protein kinase 14/0.486
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.485
1oecAA2Fibroblast growth factor receptor 2/0.484
2z97CAMCamphor 5-monooxygenase1.14.15.10.483
3e92G6AMitogen-activated protein kinase 14/0.483
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.483
4cd2FOLDihydrofolate reductase1.5.1.30.483
2zv9PP2Tyrosine-protein kinase Lyn2.7.10.20.482
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.482
1k6vXN2Gag-Pol polyprotein3.4.23.160.481
2zva1N1Tyrosine-protein kinase Lyn2.7.10.20.481
3ds6A17Mitogen-activated protein kinase 14/0.481
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.481
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.481
3tm5SFGUncharacterized protein/0.481
3zk5Z18Cytochrome P450 monooxygenase PikC/0.481
2of4979Tyrosine-protein kinase Lck2.7.10.20.480
3cd57HI3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.480
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.480
4dlj6RGMitogen-activated protein kinase 14/0.480
5e8xSTUTGF-beta receptor type-12.7.11.300.480
1bmkSB5Mitogen-activated protein kinase 14/0.479
1k6cMK1Gag-Pol polyprotein3.4.23.160.479
1nooCAHCamphor 5-monooxygenase1.14.15.10.479
2uxuNARHTH-type transcriptional regulator TtgR/0.479
2vwu7X1Ephrin type-B receptor 42.7.10.10.479
3b2w9NHTyrosine-protein kinase Lck2.7.10.20.479
3igoANPCalmodulin-domain protein kinase 1, putative/0.479
3rinI2OMitogen-activated protein kinase 14/0.479
4j95ACPFibroblast growth factor receptor 2/0.479
2eb3ANPEpidermal growth factor receptor2.7.10.10.478
3q92XNBKetohexokinase/0.478
3t2zFADSulfide-quinone reductase/0.478
4f9wLM4Mitogen-activated protein kinase 14/0.478
4xe606UDihydrofolate reductase1.5.1.30.478
1m13HYFNuclear receptor subfamily 1 group I member 2/0.477
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.477
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.477
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.477
4cd0AWJALK tyrosine kinase receptor2.7.10.10.477
4gk4L90Ephrin type-A receptor 32.7.10.10.477
4hyu1BKMitogen-activated protein kinase 82.7.11.240.477
4kbk1QGCasein kinase I isoform delta2.7.11.10.477
2rg6287Mitogen-activated protein kinase 14/0.476
3lfeZ84Mitogen-activated protein kinase 14/0.476
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.476
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.476
4jq8KJ8Epidermal growth factor receptor2.7.10.10.476
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.476
4wboANWRhodopsin kinase/0.476
2izrBRKCasein kinase I isoform gamma-32.7.11.10.475
2vn0TDZCytochrome P450 2C8/0.475
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.475
2yixYIXMitogen-activated protein kinase 14/0.475
3pt6SAHDNA (cytosine-5)-methyltransferase 12.1.1.370.475
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.475
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.475
5f0a1FBcGMP-dependent protein kinase, putative/0.475
1k6pXN3Gag-Pol polyprotein3.4.23.160.474
1qpePP2Tyrosine-protein kinase Lck2.7.10.20.474
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.474
2vd5BI8Myotonin-protein kinase2.7.11.10.474
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.474
4b99R4LMitogen-activated protein kinase 72.7.11.240.474
4btkDTQTau-tubulin kinase 12.7.11.10.474
4enhFVXCholesterol 24-hydroxylase/0.474
4fgg0U5Dihydrofolate reductase1.5.1.30.474
4g2fC07Ephrin type-A receptor 32.7.10.10.474
4hys1BJMitogen-activated protein kinase 82.7.11.240.474
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.474
1dq8COA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.473
4l3j5FIRibosomal protein S6 kinase beta-12.7.11.10.473
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.472
3jy0LYGSerine/threonine-protein kinase pim-12.7.11.10.472
3qd43Q63-phosphoinositide-dependent protein kinase 12.7.11.10.472
3uyt0CKCasein kinase I isoform delta2.7.11.10.472
3w2sW2REpidermal growth factor receptor2.7.10.10.472
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.472
4jx1CAMCamphor 5-monooxygenase1.14.15.10.472
4kb81QNCasein kinase I isoform delta2.7.11.10.472
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
2zb1GK4Mitogen-activated protein kinase 14/0.471
3t113T1Gag-Pol polyprotein3.4.23.160.471
3ttiKBIMitogen-activated protein kinase 102.7.11.240.471
4ic7ANPMitogen-activated protein kinase 72.7.11.240.471
4yuqKS1Calmodulin-like domain protein kinase/0.471
5e8wSTUTGF-beta receptor type-12.7.11.300.471
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.470
3gstGPRGlutathione S-transferase Mu 12.5.1.180.470
3l63CAMCamphor 5-monooxygenase1.14.15.10.470
3l8p0CEAngiopoietin-1 receptor2.7.10.10.470
4l4bCAMCamphor 5-monooxygenase1.14.15.10.470
1t88CAMCamphor 5-monooxygenase1.14.15.10.469
1u3dFADCryptochrome-1/0.469
2c475IDCasein kinase I isoform gamma-2/0.469
3m08RARDihydrofolate reductase1.5.1.30.469
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.469
3w2o03PEpidermal growth factor receptor2.7.10.10.469
4cp4CAMCamphor 5-monooxygenase1.14.15.10.469
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.469
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.469
4gk3L87Ephrin type-A receptor 32.7.10.10.469
4i4e1BQFocal adhesion kinase 12.7.10.20.469
4wkqIREEpidermal growth factor receptor2.7.10.10.469
1phgMYTCamphor 5-monooxygenase1.14.15.10.468
2ckeIQUDeath-associated protein kinase 2/0.468
2of2547Tyrosine-protein kinase Lck2.7.10.20.468
2oji33AMitogen-activated protein kinase 12.7.11.240.468
2vrx447Aurora kinase B-A2.7.11.10.468
3bqr4RBDeath-associated protein kinase 3/0.468
3c11GDMATP-dependent molecular chaperone HSP82/0.468
3eigMTXDihydrofolate reductase1.5.1.30.468
4dtaADNAPH(2'')-Id/0.468
1dz6CAMCamphor 5-monooxygenase1.14.15.10.467
1s9jBBMDual specificity mitogen-activated protein kinase kinase 12.7.12.20.467
2ojj82AMitogen-activated protein kinase 12.7.11.240.467
3rwpABQ3-phosphoinositide-dependent protein kinase 12.7.11.10.467
4cdmFADDeoxyribodipyrimidine photolyase/0.467
4h3c0YZDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.467
4hhy15RPoly [ADP-ribose] polymerase 12.4.2.300.467
4hnf16WCasein kinase I isoform delta2.7.11.10.467
4qmuSKESerine/threonine-protein kinase 242.7.11.10.467
1dz8CAMCamphor 5-monooxygenase1.14.15.10.466
1nzfUPGDNA beta-glucosyltransferase/0.466
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.466
2gstGPSGlutathione S-transferase Mu 12.5.1.180.466
2itnANPEpidermal growth factor receptor2.7.10.10.466
2xyuQ9GEphrin type-A receptor 42.7.10.10.466
3fwfCAMCamphor 5-monooxygenase1.14.15.10.466
3fwiCAMCamphor 5-monooxygenase1.14.15.10.466
3il1B5DGlutamate receptor 2/0.466
3qyw6PBMitogen-activated protein kinase 12.7.11.240.466
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.466
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.466
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.466
4fob0USALK tyrosine kinase receptor2.7.10.10.466
4ia3BIVVitamin D3 receptor A/0.466
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.466
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.466
1agwSU2Fibroblast growth factor receptor 1/0.465
1rx5DDFDihydrofolate reductase1.5.1.30.465
2c7xNRBCytochrome P450 monooxygenase PikC/0.465
2etm7PYFocal adhesion kinase 12.7.10.20.465
2gekGDPPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.465
2jedLG8Protein kinase C theta type2.7.11.130.465
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.465
3iqeF42F420-dependent methylenetetrahydromethanopterin dehydrogenase1.5.98.10.465
4b7sQLECytochrome P450 monooxygenase PikC/0.465
4dggI76Proto-oncogene tyrosine-protein kinase Src2.7.10.20.465
4e5yNDPGDP-L-fucose synthase1.1.1.2710.465
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.465
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.465
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.465
4qnaX11Serine/threonine-protein kinase 242.7.11.10.465
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.465
1rrmAPRLactaldehyde reductase1.1.1.770.464
1xjdSTUProtein kinase C theta type2.7.11.130.464
2a1nCAMCamphor 5-monooxygenase1.14.15.10.464
2xikJ60Serine/threonine-protein kinase 252.7.11.10.464
2yirYIRSerine/threonine-protein kinase Chk22.7.11.10.464
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.464
3jpv1DRSerine/threonine-protein kinase pim-12.7.11.10.464
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
4ekl0RFRAC-alpha serine/threonine-protein kinase2.7.11.10.464
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.464
4kiq1RAMitogen-activated protein kinase 14/0.464
1i7iAZ2Peroxisome proliferator-activated receptor gamma/0.463
1t87CAMCamphor 5-monooxygenase1.14.15.10.463
1v9aSAHUncharacterized protein/0.463
2g1pSAHDNA adenine methylase2.1.1.720.463
2gtmLIDMitogen-activated protein kinase 14/0.463
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.463
3eel53TUncharacterized protein/0.463
3iw6PP0Mitogen-activated protein kinase 14/0.463
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.463
3ttjJBIMitogen-activated protein kinase 102.7.11.240.463
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.463
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.463
3vquO22Dual specificity protein kinase TTK2.7.12.10.463
4c4jX21Dual specificity protein kinase TTK2.7.12.10.463
4jlj1NMDeoxycytidine kinase2.7.1.740.463
4n6hEJ4Delta-type opioid receptor/0.463
4qo9627Serine/threonine-protein kinase 242.7.11.10.463
1lsjNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.462
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.462
2avvMK1Gag-Pol polyprotein3.4.23.160.462
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.462
2c0tL3GTyrosine-protein kinase HCK2.7.10.20.462
2zaxCAMCamphor 5-monooxygenase1.14.15.10.462
3f5p741Insulin-like growth factor 1 receptor2.7.10.10.462
3iaeD7KBenzaldehyde lyase/0.462
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.462
3swrSFGDNA (cytosine-5)-methyltransferase 12.1.1.370.462
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.462
3u4uLNHCasein kinase II subunit alpha2.7.11.10.462
5amnDTQProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.462
5dt4ATPAurora kinase A2.7.11.10.462
1c6zROCProtease/0.461
1iwjCAMCamphor 5-monooxygenase1.14.15.10.461
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.461
2gfsPQBMitogen-activated protein kinase 14/0.461
2qo9ANPEphrin type-A receptor 32.7.10.10.461
2vwz7X6Ephrin type-B receptor 42.7.10.10.461
3hp2P36Mitogen-activated protein kinase 14/0.461
3oibFDAPutative acyl-CoA dehydrogenase/0.461
3s2pPMUCyclin-dependent kinase 22.7.11.220.461
3u9eCOALmo1369 protein/0.461
3zsi52PMitogen-activated protein kinase 14/0.461
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.461
4g6oE28Mitogen-activated protein kinase 12.7.11.240.461
4gk2L66Ephrin type-A receptor 32.7.10.10.461
4gu610NFocal adhesion kinase 12.7.10.20.461
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4hvg19QTyrosine-protein kinase JAK32.7.10.20.461
4iebANPCalmodulin-domain protein kinase 1/0.461
4mxyDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.461
4mxzDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.461
4mzuCOAWxcM-like protein/0.461
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.461
1lhvNOGSex hormone-binding globulin/0.460
1me8RVPInosine-5'-monophosphate dehydrogenase/0.460
1xkkFMMEpidermal growth factor receptor2.7.10.10.460
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.460
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.460
3a9wNADNDP-sugar epimerase/0.460
3lijANPCalcium/calmodulin dependent protein kinase with a kinase domain and 4 calmodulin like EF hands/0.460
3nwxKVSGag-Pol polyprotein3.4.23.160.460
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.460
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.460
4ib4ERM5-hydroxytryptamine receptor 2B/0.460
5aabVGHALK tyrosine kinase receptor2.7.10.10.460
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.460
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.459
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.459
2bl4NADLactaldehyde reductase1.1.1.770.459
2ewaSB2Mitogen-activated protein kinase 14/0.459
2pc9ATPPhosphoenolpyruvate carboxykinase (ATP)/0.459
2vx07X7Ephrin type-B receptor 42.7.10.10.459
2y9qANPMitogen-activated protein kinase 12.7.11.240.459
3fwjCAMCamphor 5-monooxygenase1.14.15.10.459
3umw596Serine/threonine-protein kinase pim-12.7.11.10.459
4asf62UATP-dependent molecular chaperone HSP82/0.459
4c4h7RODual specificity protein kinase TTK2.7.12.10.459
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.459
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.459
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.459
4h50NAPBiphenyl dioxygenase ferredoxin reductase subunit/0.459
4nmbFADBifunctional protein PutA/0.459
4qmlANPSerine/threonine-protein kinase 242.7.11.10.459
5aaaVGHALK tyrosine kinase receptor2.7.10.10.459
1h1s4SPCyclin-dependent kinase 22.7.11.220.458
1nzdUPGDNA beta-glucosyltransferase/0.458
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.458
1yrcCAMCamphor 5-monooxygenase1.14.15.10.458
2a7r5GPGMP reductase 2/0.458
2izt23DCasein kinase I isoform gamma-32.7.11.10.458
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.458
3ac3KSHTyrosine-protein kinase Lck2.7.10.20.458
3dxjNE6DNA-directed RNA polymerase subunit beta/0.458
3dxjNE6DNA-directed RNA polymerase subunit beta'/0.458
3nwq2NCGag-Pol polyprotein3.4.23.160.458
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.458
3zokNAD3-dehydroquinate synthase, chloroplastic4.2.3.40.458
4bdbODOSerine/threonine-protein kinase Chk22.7.11.10.458
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4ho5DAUGlucose-1-phosphate thymidylyltransferase/0.458
4o701QKBromodomain-containing protein 4/0.458
4zolACPTubulin tyrosine ligase/0.458
1me7MOAInosine-5'-monophosphate dehydrogenase/0.457
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.457
2idw017Protease/0.457
2j7t274Serine/threonine-protein kinase 102.7.11.10.457
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.457
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.457
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.457
3b2tM33Fibroblast growth factor receptor 2/0.457
3d8vUD1Bifunctional protein GlmU/0.457
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.457
3inxJZCHeat shock protein HSP 90-alpha/0.457
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.457
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.457
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.457
4dce0JFALK tyrosine kinase receptor2.7.10.10.457
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4fnzNZFALK tyrosine kinase receptor2.7.10.10.457
4gaeNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.457
4lgh0JNProto-oncogene tyrosine-protein kinase Src2.7.10.20.457
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.457
1di8DTQCyclin-dependent kinase 22.7.11.220.456
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
1jioDEB6-deoxyerythronolide B hydroxylase/0.456
1k6tXN1Gag-Pol polyprotein3.4.23.160.456
1ml3NADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.456
1w7h3IPMitogen-activated protein kinase 14/0.456
1wvxBD4Death-associated protein kinase 12.7.11.10.456
1xl2189Gag-Pol polyprotein3.4.23.160.456
1ywnLIFVascular endothelial growth factor receptor 22.7.10.10.456
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.456
2cd8PXICytochrome P450 monooxygenase PikC/0.456
2dwbANPAurora kinase A2.7.11.10.456
2hog710Serine/threonine-protein kinase Chk12.7.11.10.456
2k62ITLFatty acid-binding protein, liver/0.456
2xvdAS6Ephrin type-B receptor 42.7.10.10.456
3el51UNGag-Pol polyprotein/0.456
3qly55VUncharacterized protein/0.456
4appN53Serine/threonine-protein kinase PAK 42.7.11.10.456
4asg814ATP-dependent molecular chaperone HSP82/0.456
4b5bBBEGlucose-1-phosphate thymidylyltransferase/0.456
4ek1CAMCamphor 5-monooxygenase1.14.15.10.456
4fic0ULProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
4id71G0Activated CDC42 kinase 1/0.456
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.456
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.456
1rbyKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.455
1rk3VDXVitamin D3 receptor/0.455
1uu3LY43-phosphoinositide-dependent protein kinase 12.7.11.10.455
2bujSTUSerine/threonine-protein kinase 16/0.455
2m56CAMCamphor 5-monooxygenase1.14.15.10.455
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.455
2wouZZFTGF-beta receptor type-12.7.11.300.455
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.455
3a62STURibosomal protein S6 kinase beta-12.7.11.10.455
3d7zGK5Mitogen-activated protein kinase 14/0.455
3idsNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.455
3qaiXNNKetohexokinase/0.455
4a6bQG8Gag-Pol polyprotein3.4.23.160.455
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.455
4o4fATPKinase/0.455
4tuvCPZCytochrome P450 1191.140.455
1bygSTUTyrosine-protein kinase CSK/0.454
1e7qNAPGDP-L-fucose synthase/0.454
1hncGDNGlutathione S-transferase Mu 22.5.1.180.454
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.454
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.454
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.454
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.454
2izsBRQCasein kinase I isoform gamma-32.7.11.10.454
2j0k4STFocal adhesion kinase 12.7.10.20.454
2o0uC0MMitogen-activated protein kinase 102.7.11.240.454
2vwx7X4Ephrin type-B receptor 42.7.10.10.454
3grySAMProbable ribosomal RNA small subunit methyltransferase A/0.454
3h9f92MDual specificity protein kinase TTK2.7.12.10.454
3k3bADPKinesin-like protein KIF11/0.454
3lxiCAMCytochrome P450/0.454
3nc9TR3Ketohexokinase/0.454
4ei7GDPPlasmid replication protein RepX/0.454
4f650S9Fibroblast growth factor receptor 1/0.454
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.454
4h1j0YHProtein-tyrosine kinase 2-beta2.7.10.20.454
4l455FIRibosomal protein S6 kinase beta-12.7.11.10.454
4ubsDIFPentalenic acid synthase1.14.15.110.454
1u54ACPActivated CDC42 kinase 1/0.453
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.453
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.453
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.453
3ac5KZMTyrosine-protein kinase Lck2.7.10.20.453
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.453
3c5uP41Mitogen-activated protein kinase 14/0.453
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3eem53VUncharacterized protein/0.453
3lfa1N1Mitogen-activated protein kinase 14/0.453
3t2yFADSulfide-quinone reductase/0.453
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.453
3uleC69Actin-related protein 3/0.453
3vetADPnebramycin 5' synthase6.1.2.20.453
3vrwYS5Vitamin D3 receptor/0.453
3vs3VSETyrosine-protein kinase HCK2.7.10.20.453
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.453
4dt8ADNAPH(2'')-Id/0.453
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.453
4i41MIXSerine/threonine-protein kinase pim-12.7.11.10.453
4ii5ADPCyclin-dependent kinase 22.7.11.220.453
4j54G52Gag-Pol polyprotein3.4.23.160.453
4jx1CAHCamphor 5-monooxygenase1.14.15.10.453
4otiMI1Serine/threonine-protein kinase N1/0.453
4py6R78Bromodomain protein, putative/0.453
5cp4CAMCamphor 5-monooxygenase1.14.15.10.453
5itzLOCTubulin beta-2B chain/0.453
1j39UPGDNA beta-glucosyltransferase/0.452
1rm4NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.452
1yolS03Proto-oncogene tyrosine-protein kinase Src2.7.10.20.452
1yp3ATPGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.452
2baqPQBMitogen-activated protein kinase 14/0.452
2bi4NADLactaldehyde reductase1.1.1.770.452
2c6hPXICytochrome P450 monooxygenase PikC/0.452
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.452
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.452
2vwy7X5Ephrin type-B receptor 42.7.10.10.452
3at4CCKCasein kinase II subunit alpha2.7.11.10.452
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
3hv3R49Mitogen-activated protein kinase 14/0.452
3ocgOCGMitogen-activated protein kinase 14/0.452
3q5iANPProtein kinase, putative/0.452
3t2kFADSulfide-quinone reductase/0.452
3t54ATPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.452
3tqhNDPQuinone oxidoreductase/0.452
3wd7COAAcridone synthase/0.452
4eh3NARMitogen-activated protein kinase 14/0.452
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4fv8E63Mitogen-activated protein kinase 12.7.11.240.452
4p8rNADGlyceraldehyde-3-phosphate dehydrogenase/0.452
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.452
6cp4CAMCamphor 5-monooxygenase1.14.15.10.452
4z34ON7Lysophosphatidic acid receptor 1/0.452
1bvgDMPGag-Pol polyprotein3.4.23.160.451
1bxsNADRetinal dehydrogenase 11.2.1.360.451
1oiyN41Cyclin-dependent kinase 22.7.11.220.451
1sejF89Bifunctional dihydrofolate reductase-thymidylate synthase/0.451
2f4jVX6Tyrosine-protein kinase ABL12.7.10.20.451
3dj4UD1Bifunctional protein GlmU/0.451
3eej53RUncharacterized protein/0.451
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.451
3pj8404Cyclin-dependent kinase 22.7.11.220.451
3vtdTKDVitamin D3 receptor/0.451
4bi1ZO6Dual specificity protein kinase TTK2.7.12.10.451
4e730NRMitogen-activated protein kinase 82.7.11.240.451
4gu94GUFocal adhesion kinase 12.7.10.20.451
4jia1K3Tyrosine-protein kinase JAK2/0.451
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.451
4kba1QMCasein kinase I isoform delta2.7.11.10.451
4kip1R9Mitogen-activated protein kinase 14/0.451
4ykgFADAlkyl hydroperoxide reductase subunit F1.8.10.451
1dq9HMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.450
1iwiCAMCamphor 5-monooxygenase1.14.15.10.450
1kgjFL8Transthyretin/0.450
1rx7FOLDihydrofolate reductase1.5.1.30.450
1tdrMTXDihydrofolate reductase1.5.1.30.450
1zys199Serine/threonine-protein kinase Chk12.7.11.10.450
2qoqANPEphrin type-A receptor 32.7.10.10.450
2wleCOAPolysialic acid O-acetyltransferase/0.450
2x3nFADProbable FAD-dependent monooxygenase/0.450
2x7gPVBSRSF protein kinase 22.7.11.10.450
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
2zm4KSMTyrosine-protein kinase Lck2.7.10.20.450
3ad6KSCTyrosine-protein kinase Lck2.7.10.20.450
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.450
3emg685Tyrosine-protein kinase SYK2.7.10.20.450
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.450
3jw3TOPDihydrofolate reductase/0.450
3ka0MK3MAP kinase-activated protein kinase 22.7.11.10.450
3pp1IZGDual specificity mitogen-activated protein kinase kinase 12.7.12.20.450
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.450
3vjnANPEpidermal growth factor receptor2.7.10.10.450
3wrmCAMCamphor 5-monooxygenase1.14.15.10.450
3wy0COAUncharacterized protein/0.450
4c4iX20Dual specificity protein kinase TTK2.7.12.10.450
4eipK2CPutative FAD-monooxygenase/0.450
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.450
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.450
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.450
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.450
4pkl1GHUncharacterized protein/0.450
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.450
5auxKMPDeath-associated protein kinase 12.7.11.10.450
1tz8DESTransthyretin/0.449
1u3cFADCryptochrome-1/0.449
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.449
2o65MYFSerine/threonine-protein kinase pim-12.7.11.10.449
3dcv55ESerine/threonine-protein kinase pim-12.7.11.10.449
3kpkFADSulfide-quinone reductase/0.449
3l0lHC3Nuclear receptor ROR-gamma/0.449
3lfcZ86Mitogen-activated protein kinase 14/0.449
3oy4017Gag-Pol polyprotein3.4.23.160.449
3sa323XProtease/0.449
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.449
4an35Y0Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.449
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.449
4g1y0VOVitamin D3 receptor A/0.449
4k9yK9YFocal adhesion kinase 12.7.10.20.449
4mb2ATPUncharacterized protein/0.449
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
4x4lNAIRetinal dehydrogenase 11.2.1.360.449
4xivACPChemotaxis protein CheA2.7.13.30.449
5k2cZMAAdenosine receptor A2a/0.449
1osfKOSHeat shock protein HSP 90-alpha/0.448
2cppCAMCamphor 5-monooxygenase1.14.15.10.448
2oz6CMPCyclic AMP receptor-like protein/0.448
2q66ATPPoly(A) polymerase2.7.7.190.448
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.448
2vww7X2Ephrin type-B receptor 42.7.10.10.448
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.448
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.448
3fsuC2F5,10-methylenetetrahydrofolate reductase1.5.1.200.448
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.448
3ibdCPZCytochrome P450 2B61.14.130.448
3jwcEKBDihydrofolate reductase/0.448
3mdvCL6Cholesterol 24-hydroxylase/0.448
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3orzBI43-phosphoinositide-dependent protein kinase 12.7.11.10.448
3sgx0FWDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.448
3t3c017Gag-Pol polyprotein3.4.23.160.448
3vt8YI3Vitamin D3 receptor/0.448
3w9rA8SAbscisic acid receptor PYL9/0.448
3wrjCAMCamphor 5-monooxygenase1.14.15.10.448
3zuyTCHTransporter/0.448
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.448
4dfrMTXDihydrofolate reductase1.5.1.30.448
4e8yIHAD-beta-D-heptose 7-phosphate kinase/0.448
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.448
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.448
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.448
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4h9506UDihydrofolate reductase1.5.1.30.448
4iarERM5-hydroxytryptamine receptor 1B/0.448
4o59NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.448
1bveDMPGag-Pol polyprotein3.4.23.160.447
1cd2FOLDihydrofolate reductase1.5.1.30.447
1yonA2R2-dehydropantoate 2-reductase1.1.1.1690.447
1yvj4STTyrosine-protein kinase JAK32.7.10.20.447
1zeoC01Peroxisome proliferator-activated receptor gamma/0.447
2bpz3INGag-Pol polyprotein3.4.23.160.447
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.447
2ephASP_TRP_ASNFructose-bisphosphate aldolase4.1.2.130.447
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
2pzrACPFibroblast growth factor receptor 2/0.447
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2wpa889Cyclin-dependent kinase 22.7.11.220.447
3ac2KSETyrosine-protein kinase Lck2.7.10.20.447
3ajrNADNDP-sugar epimerase/0.447
3cseN22Uncharacterized protein/0.447
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.447
3fl8RARDihydrofolate reductase/0.447
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.447
3o9cK20Pol polyprotein/0.447
3sz0FADSulfide-quinone reductase/0.447
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.447
4b2wBZ0Glucose-1-phosphate thymidylyltransferase/0.447
4dscA8SAbscisic acid receptor PYL3/0.447
4elb34RDihydrofolate reductase/0.447
4fkpLS5Cyclin-dependent kinase 22.7.11.220.447
4hge15VTyrosine-protein kinase JAK2/0.447
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.447
4ia7BIVVitamin D3 receptor A/0.447
4l4dCAMCamphor 5-monooxygenase1.14.15.10.447
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.447
6gswGPSGlutathione S-transferase Mu 12.5.1.180.447
5jtbZMAAdenosine receptor A2a/0.447
1aq1STUCyclin-dependent kinase 22.7.11.220.446
1eh4IC1Casein kinase I homolog 12.7.11.10.446
1errRALEstrogen receptor/0.446
1i8tFADUDP-galactopyranose mutase5.4.99.90.446
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.446
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.446
1pl8NADSorbitol dehydrogenase1.1.1.140.446
1qzfCB3Bifunctional dihydrofolate reductase-thymidylate synthase/0.446
1uu9BI33-phosphoinositide-dependent protein kinase 12.7.11.10.446
1w8cN69Cyclin-dependent kinase 22.7.11.220.446
1yp4ADQGlucose-1-phosphate adenylyltransferase small subunit, chloroplastic/amyloplastic2.7.7.270.446
1yrdCAMCamphor 5-monooxygenase1.14.15.10.446
2c6eHPMAurora kinase A2.7.11.10.446
2r43G3GGag-Pol polyprotein3.4.23.160.446
2uwd2GGHeat shock protein HSP 90-alpha/0.446
2uxoTACHTH-type transcriptional regulator TtgR/0.446
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.446
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.446
3fl9TOPDihydrofolate reductase/0.446
3mtfA3FActivin receptor type-12.7.11.300.446
3t14FADSulfide-quinone reductase/0.446
3t9aANPInositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase 2/0.446
3vnt0JAVascular endothelial growth factor receptor 22.7.10.10.446
3wrhCAMCamphor 5-monooxygenase1.14.15.10.446
3wrlCAMCamphor 5-monooxygenase1.14.15.10.446
3ztxZTXAurora kinase B-A2.7.11.10.446
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
4a6nFADTetX family tetracycline inactivation enzyme/0.446
4a99FADTetX family tetracycline inactivation enzyme/0.446
4bcqTJFCyclin-dependent kinase 22.7.11.220.446
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.446
4c58824Cyclin-G-associated kinase2.7.11.10.446
4enyJ19Serine/threonine-protein kinase pim-12.7.11.10.446
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.446
4g3rCAMCamphor 5-monooxygenase1.14.15.10.446
4hvi19STyrosine-protein kinase JAK32.7.10.20.446
4k2xFADPolyketide oxygenase/hydroxylase/0.446
4mvfSTUCalcium-dependent protein kinase 22.7.11.10.446
4nj32KDCyclin-dependent kinase 22.7.11.220.446
4r21STRCytochrome P450 family 17 polypeptide 2/0.446
4s34ANPMitogen-activated protein kinase 12.7.11.240.446
1cdeGARPhosphoribosylglycinamide formyltransferase/0.445
1dnpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.445
1jklANPDeath-associated protein kinase 12.7.11.10.445
1kijNOVDNA gyrase subunit B/0.445
1og5SWFCytochrome P450 2C9/0.445
1suoCPZCytochrome P450 2B41.14.14.10.445
1sx4ADP60 kDa chaperonin/0.445
1w2xRCPAcetyl-CoA carboxylase/0.445
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.445
2acxANPG protein-coupled receptor kinase 62.7.11.160.445
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.445
2ca0PXICytochrome P450 monooxygenase PikC/0.445
2chlDKICasein kinase I isoform gamma-32.7.11.10.445
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.445
2fziDH3Dihydrofolate reductase1.5.1.30.445
2gpuOHTEstrogen-related receptor gamma/0.445
2i1vADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.445
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.445
2prh238Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2x2kX2KProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.445
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.445
2xp2VGHALK tyrosine kinase receptor2.7.10.10.445
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.445
2zlcVDXVitamin D3 receptor/0.445
3aidARQGag-Pol polyprotein3.4.23.160.445
3e5rNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.445
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.445
3fzsB96Protein-tyrosine kinase 2-beta2.7.10.20.445
3gggNADPrephenate dehydrogenase/0.445
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.445
3iw7IPKMitogen-activated protein kinase 14/0.445
3kytHC2Nuclear receptor ROR-gamma/0.445
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.445
3od0PCGcGMP-dependent protein kinase 12.7.11.120.445
3ogqAB1Pol polyprotein/0.445
3opdHIEHeat shock protein 83/0.445
3s1cZIRCytokinin dehydrogenase 11.5.99.120.445
3syiFADSulfide-quinone reductase/0.445
3v04V04Dual specificity mitogen-activated protein kinase kinase 12.7.12.20.445
4a9rRU5Serine/threonine-protein kinase Chk22.7.11.10.445
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.445
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.445
4dymIYZActivin receptor type-12.7.11.300.445
4jbqVX6Aurora kinase A2.7.11.10.445
4ly91YYGlucokinase regulatory protein/0.445
4riyADPEpidermal growth factor receptor2.7.10.10.445
4z07PCGcGMP-dependent protein kinase 12.7.11.120.445
6gsxGPSGlutathione S-transferase Mu 12.5.1.180.445
1dz4CAMCamphor 5-monooxygenase1.14.15.10.444
1ie4T44Transthyretin/0.444
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.444
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.444
1t1sCBQ1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.444
1xr1ANPSerine/threonine-protein kinase pim-12.7.11.10.444
2e9cB75Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.444
2gtnLIEMitogen-activated protein kinase 14/0.444
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.444
2oxtSAMGenome polyprotein/0.444
2uzvSS5cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2vgoAD5Aurora kinase B-A2.7.11.10.444
2w1fL0FAurora kinase A2.7.11.10.444
2wotZZGTGF-beta receptor type-12.7.11.300.444
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.444
2xa4AZ5Tyrosine-protein kinase JAK2/0.444
2xru400Aurora kinase A2.7.11.10.444
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.444
3d7tSTUTyrosine-protein kinase CSK/0.444
3drcMTXDihydrofolate reductase1.5.1.30.444
3ezrEZRCyclin-dependent kinase 22.7.11.220.444
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.444
3hv6R39Mitogen-activated protein kinase 14/0.444
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.444
3p79P79Mitogen-activated protein kinase 14/0.444
4c4f7CEDual specificity protein kinase TTK2.7.12.10.444
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.444
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4fv9E71Mitogen-activated protein kinase 12.7.11.240.444
4gt3ATPMitogen-activated protein kinase 12.7.11.240.444
4hgt15GCasein kinase I isoform delta2.7.11.10.444
4hnc0UTMandelate racemase/0.444
4hni16WCasein kinase I isoform epsilon2.7.11.10.444
4kbc1QJCasein kinase I isoform delta2.7.11.10.444
4kf1HT5Aryldialkylphosphatase3.1.8.10.444
4lrzADPPEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.444
4upjU04Gag-Pol polyprotein/0.444
5cb4ACPTubulin tyrosine ligase/0.444
1c3eGARPhosphoribosylglycinamide formyltransferase/0.443
1dnaCB3Thymidylate synthase/0.443
1pdhFASp-hydroxybenzoate hydroxylase/0.443
1t86CAMCamphor 5-monooxygenase1.14.15.10.443
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
2bxe1FLSerum albumin/0.443
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.443
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
2oapANPType II secretion system protein (GspE-2)/0.443
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.443
2uxhQUEHTH-type transcriptional regulator TtgR/0.443
2vx17X8Ephrin type-B receptor 42.7.10.10.443
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.443
2y7jB49Phosphorylase b kinase gamma catalytic chain, liver/testis isoform2.7.11.190.443
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.443
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.443
3bwjARXcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.443
3cppCAMCamphor 5-monooxygenase1.14.15.10.443
3dpd41APhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.443
3p6nDSOCamphor 5-monooxygenase1.14.15.10.443
3qa2XNAKetohexokinase/0.443
3sai9DRDihydrofolate reductase/0.443
3tm4SAMUncharacterized protein/0.443
3v76FDAUncharacterized protein/0.443
3w2rW2REpidermal growth factor receptor2.7.10.10.443
4axdANPInositol-pentakisphosphate 2-kinase2.7.1.1580.443
4elf35IDihydrofolate reductase/0.443
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.443
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.443
4h9753SDihydrofolate reductase1.5.1.30.443
4hy6FJ1Heat shock protein HSP 90-alpha/0.443
4i22IREEpidermal growth factor receptor2.7.10.10.443
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.443
4xxvNAD3-isopropylmalate dehydrogenase/0.443
5eypLOCTubulin beta chain/0.443
5uviZMAAdenosine receptor A2a/0.443
1c2tGARPhosphoribosylglycinamide formyltransferase/0.442
1d4sTPVGag-Pol polyprotein3.4.23.160.442
1f4fTP3Thymidylate synthase/0.442
1g1lDAUGlucose-1-phosphate thymidylyltransferase/0.442
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.442
1ictT44Transthyretin/0.442
1jqhANPInsulin-like growth factor 1 receptor2.7.10.10.442
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.442
1yb5NAPQuinone oxidoreductase1.6.5.50.442
1zrzBI1Protein kinase C iota type2.7.11.130.442
2b1pAIZMitogen-activated protein kinase 102.7.11.240.442
2excJNKMitogen-activated protein kinase 102.7.11.240.442
2exlGDMEndoplasmin/0.442
2fdd385Pol protein/0.442
2itxANPEpidermal growth factor receptor2.7.10.10.442
2j0j4STFocal adhesion kinase 12.7.10.20.442
2qocANPEphrin type-A receptor 32.7.10.10.442
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.442
2yfxVGHALK tyrosine kinase receptor2.7.10.10.442
3ac1KZITyrosine-protein kinase Lck2.7.10.20.442
3acjKSSTyrosine-protein kinase Lck2.7.10.20.442
3bgxMEFThymidylate synthase/0.442
3dmtNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.442
3em6017Gag-Pol polyprotein3.4.23.160.442
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.442
3jwm5WBDihydrofolate reductase/0.442
3mdmFJZCholesterol 24-hydroxylase/0.442
3pejBC2Endoplasmin homolog, putative/0.442
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.442
3qd33Q53-phosphoinositide-dependent protein kinase 12.7.11.10.442
3vtcTK3Vitamin D3 receptor/0.442
3wmxNADNAD dependent epimerase/dehydratase/0.442
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.442
4c9pCAMCytochrome P450/0.442
4egh0OYHeat shock protein HSP 90-alpha/0.442
4fr0SAMArsenic methyltransferase/0.442
4hhz15SPoly [ADP-ribose] polymerase 12.4.2.300.442
4ia2BIVVitamin D3 receptor A/0.442
4ih8B43Calmodulin-domain protein kinase 1/0.442
4l8u9AZSerum albumin/0.442
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.442
4oaeCLMUncharacterized protein/0.442
4ryvZEAProtein LlR18A/0.442
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.442
4xdmGDMHeat shock cognate 90 kDa protein/0.442
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
1bdqIM1Gag-Pol polyprotein3.4.23.160.441
1cbfSAHCobalt-precorrin-4 C(11)-methyltransferase2.1.1.2710.441
1db1VDXVitamin D3 receptor/0.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.441
1m2pHNACasein kinase II subunit alpha2.7.11.10.441
1meiMOAInosine-5'-monophosphate dehydrogenase/0.441
1mvsDTMDihydrofolate reductase1.5.1.30.441
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.441
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.441
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.441
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
2i40BLZCyclin-dependent kinase 22.7.11.220.441
2ijmADPFocal adhesion kinase 12.7.10.20.441
2jkoBIJFocal adhesion kinase 12.7.10.20.441
2o4rVD5Vitamin D3 receptor/0.441
2qd7065Gag-Pol polyprotein3.4.23.160.441
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2w2lNADD-mandelate dehydrogenase/0.441
2wghDTPRibonucleoside-diphosphate reductase large subunit1.17.4.10.441
2ycrHCWSerine/threonine-protein kinase Chk22.7.11.10.441
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.441
3bheBZNGag-Pol polyprotein3.4.23.160.441
3du8553Glycogen synthase kinase-3 beta2.7.11.260.441
3fgoCZASarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.441
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.441
3och2MXDihydrofolate reductase1.5.1.30.441
3qlrNDPDihydrofolate reductase1.5.1.30.441
3sheI85MAP kinase-activated protein kinase 32.7.11.10.441
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.441
3vbq0F5Serine/threonine-protein kinase pim-12.7.11.10.441
3vt3VDXVitamin D3 receptor/0.441
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.441
4a9mP9MBromodomain-containing protein 2/0.441
4bb432WEphrin type-B receptor 42.7.10.10.441
4c02TAKActivin receptor type-12.7.11.300.441
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.441
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.441
4g160VMCasein kinase I isoform gamma-32.7.11.10.441
4g1d0VKVitamin D3 receptor A/0.441
4g95OAGDihydrofolate reductase1.5.1.30.441
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.441
4u0i0LIMast/stem cell growth factor receptor Kit2.7.10.10.441
4wq5ATPtRNA N6-adenosine threonylcarbamoyltransferase/0.441
4xhgADPUncharacterized protein/0.441
4xivADPChemotaxis protein CheA2.7.13.30.441
5br7FADUDP-galactopyranose mutase/0.441
5dmzADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.441
1fmlRTLRetinol dehydratase/0.440
1hvyD16Thymidylate synthase2.1.1.450.440
1mb9ATPCarboxyethyl-arginine beta-lactam-synthase6.3.3.40.440
1nmdATPMajor actin/0.440
1np7FADCryptochrome DASH/0.440
1r78FMDCyclin-dependent kinase 22.7.11.220.440
1re9DSOCamphor 5-monooxygenase1.14.15.10.440
1rx3MTXDihydrofolate reductase1.5.1.30.440
1vjy460TGF-beta receptor type-12.7.11.300.440
1wvySTUDeath-associated protein kinase 12.7.11.10.440
1yt9OISGag-Pol polyprotein/0.440
2bsmBSMHeat shock protein HSP 90-alpha/0.440
2cchATPCyclin-dependent kinase 22.7.11.220.440
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.440
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.440
2ph5NADHomospermidine synthase/0.440
2pwcG3GGag-Pol polyprotein3.4.23.160.440
2ycsNXPSerine/threonine-protein kinase Chk22.7.11.10.440
3anxMTAPolyamine aminopropyltransferase/0.440
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3b20NADGlyceraldehyde-3-phosphate dehydrogenase/0.440
3c4xATPRhodopsin kinase/0.440
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.440
3mnrSD1Heat shock protein HSP 90-alpha/0.440
3oom507Activin receptor type-12.7.11.300.440
3sa27DRDihydrofolate reductase/0.440
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.440
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.440
4aqc88ATyrosine-protein kinase JAK2/0.440
4baeRWXDNA gyrase subunit B/0.440
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.440
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4fod0UVALK tyrosine kinase receptor2.7.10.10.440
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.440
4gub0Y4Casein kinase II subunit alpha2.7.11.10.440
4i3vNADAldehyde dehydrogenase (NAD+)/0.440
4ix6ADPUncharacterized protein/0.440
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.440
4lv7ADPInositol-pentakisphosphate 2-kinase2.7.1.1580.440
4nc3ERM5-hydroxytryptamine receptor 2B/0.440
4qms1N1Serine/threonine-protein kinase 242.7.11.10.440
4ruoBIVVitamin D3 receptor A/0.440
4s33ANPMitogen-activated protein kinase 12.7.11.240.440
4wb9NAIRetinal dehydrogenase 11.2.1.360.440
4wsqKSAAP2-associated protein kinase 12.7.11.10.440
4z44FADFlavin-dependent tryptophan halogenase PrnA1.14.19.90.440
5ap57RODual specificity protein kinase TTK2.7.12.10.440
5dpvSKEAurora kinase A2.7.11.10.440
5hi6MTXDihydrofolate reductase/0.440