sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2xk6 | EQH | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 1.000 | |
| 2xk3 | XK3 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.706 | |
| 2xk8 | 5R1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.647 | |
| 2xnm | WGZ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.632 | |
| 2xke | WI2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.623 | |
| 2xkd | T3M | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.617 | |
| 2wqo | VGK | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.607 | |
| 2yac | 937 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.600 | |
| 2xkf | BX1 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.599 | |
| 4a4l | 939 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.591 | |
| 4a4x | JUP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.591 | |
| 2xk4 | OL2 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.586 | |
| 4afe | GGY | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.585 | |
| 2xk7 | 30E | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.573 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.569 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.566 | |
| 2xnp | WCX | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.560 | |
| 2xno | ED8 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.558 | |
| 4j52 | 1J3 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.557 | |
| 4i6f | 1C7 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.556 | |
| 2rku | R78 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.549 | |
| 2w5b | AGS | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.548 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.544 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.542 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.527 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.525 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.523 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.517 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.517 | |
| 4b6l | 9ZP | Serine/threonine-protein kinase PLK3 | 2.7.11.21 | 0.513 | |
| 2io6 | 330 | Wee1-like protein kinase | 2.7.10.2 | 0.509 | |
| 2z2w | 770 | Wee1-like protein kinase | 2.7.10.2 | 0.508 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.503 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.502 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.501 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.499 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.499 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.499 | |
| 4jau | ADP | Sensor histidine kinase | / | 0.499 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.496 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.496 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.496 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.495 | |
| 2zrv | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.495 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.494 | |
| 4xul | GTP | Uncharacterized protein mg662 | / | 0.494 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.493 | |
| 1t4c | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.492 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.492 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.492 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.491 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.490 | |
| 2uvy | GVI | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.490 | |
| 4fny | I3K | ALK tyrosine kinase receptor | 2.7.10.1 | 0.490 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.488 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.488 | |
| 4pnm | NU1 | Tankyrase-2 | 2.4.2.30 | 0.488 | |
| 1d3d | BZT | Prothrombin | 3.4.21.5 | 0.487 | |
| 1ozq | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.487 | |
| 2ejz | SAH | Diphthine synthase | / | 0.487 | |
| 2xtb | KRM | Adenosine kinase, putative | / | 0.487 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.487 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.487 | |
| 3htj | ET | EbrA repressor | / | 0.486 | |
| 3hxe | BD8 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.486 | |
| 1euy | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.485 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.485 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.484 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.484 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.484 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.484 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.483 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.483 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.482 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.482 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.482 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.482 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.481 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.481 | |
| 3ebi | BEY | M1 family aminopeptidase | 3.4.11 | 0.481 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.480 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.480 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.480 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.480 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.480 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.479 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.478 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.478 | |
| 2xvv | 9DN | Serum albumin | / | 0.478 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.478 | |
| 3blo | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.478 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.478 | |
| 1odn | APV | Isopenicillin N synthase | 1.21.3.1 | 0.477 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.477 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.477 | |
| 2ywv | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | / | 0.477 | |
| 4h6z | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.477 | |
| 2b37 | 8PS | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.476 | |
| 2fb8 | 215 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.476 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.476 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.476 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.476 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.476 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.475 | |
| 3b05 | IPE | Isopentenyl-diphosphate delta-isomerase | / | 0.475 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.475 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.475 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.474 | |
| 2w2x | GSP | Ras-related C3 botulinum toxin substrate 2 | / | 0.474 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.474 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.474 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.474 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.474 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.473 | |
| 2x23 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.473 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.473 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.473 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.473 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
| 2vdm | AGG | Integrin alpha-IIb | / | 0.472 | |
| 2vdm | AGG | Integrin beta-3 | / | 0.472 | |
| 3cqe | P91 | Wee1-like protein kinase | 2.7.10.2 | 0.472 | |
| 3gf4 | U5P | UDP-galactopyranose mutase | 5.4.99.9 | 0.472 | |
| 3s41 | S41 | Glucokinase | 2.7.1.2 | 0.472 | |
| 4jva | 1OR | cAMP-dependent protein kinase type II-beta regulatory subunit | / | 0.472 | |
| 4phl | PIL | Phosphodiesterase | / | 0.472 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.471 | |
| 1qrs | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.471 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.471 | |
| 3gyf | 51P | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.471 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.471 | |
| 3qri | 919 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.471 | |
| 4bgi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.471 | |
| 5jtb | ZMA | Adenosine receptor A2a | / | 0.471 | |
| 1d3p | BT3 | Prothrombin | 3.4.21.5 | 0.470 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.470 | |
| 1u0w | STL | Chalcone synthase 2 | 2.3.1.74 | 0.470 | |
| 3ntr | NAD | Inositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase | 1.1.1.18 | 0.470 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.470 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.470 | |
| 1efz | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.469 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.469 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.469 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.469 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.469 | |
| 5dp2 | NAP | CurF | / | 0.469 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.468 | |
| 1k4g | AIQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.468 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.468 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.468 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2jav | 5Z5 | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.468 | |
| 2jh0 | 701 | Prothrombin | 3.4.21.5 | 0.468 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.468 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.468 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 3oct | 1N1 | Tyrosine-protein kinase BTK | 2.7.10.2 | 0.468 | |
| 4h7z | GUN | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.468 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.468 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.467 | |
| 2gq3 | COA | Malate synthase G | / | 0.467 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.467 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.467 | |
| 3fvq | ATP | Fe(3+) ions import ATP-binding protein FbpC | / | 0.467 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.467 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.467 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.466 | |
| 1qs2 | NAD | Vip2Ac | / | 0.466 | |
| 1rgs | CMP | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.466 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.466 | |
| 1t57 | FMN | Conserved protein | / | 0.466 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.466 | |
| 2eeq | SAH | Diphthine synthase | / | 0.466 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.466 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.466 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.466 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.466 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.466 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.465 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.465 | |
| 3d7z | GK5 | Mitogen-activated protein kinase 14 | / | 0.465 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.465 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.465 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.465 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.465 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.465 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.464 | |
| 1w1w | AGS | Structural maintenance of chromosomes protein 1 | / | 0.464 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.464 | |
| 2cfc | KPC | 2-(R)-hydroxypropyl-CoM dehydrogenase | 1.1.1.268 | 0.464 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.464 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.464 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.464 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.464 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.464 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.464 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.463 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.463 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.463 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.463 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.463 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.462 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.462 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.462 | |
| 2b01 | TUD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.462 | |
| 2bak | AQZ | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3ar4 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.462 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.462 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 4a9y | AQZ | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 4f31 | KAI | Glutamate receptor 3 | / | 0.462 | |
| 4htx | 19F | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.462 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.462 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.462 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.462 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.461 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.461 | |
| 1swt | BTN | Streptavidin | / | 0.461 | |
| 1w83 | L11 | Mitogen-activated protein kinase 14 | / | 0.461 | |
| 1z4i | UMP | 5'(3')-deoxyribonucleotidase, mitochondrial | 3.1.3 | 0.461 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.461 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.461 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.461 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.461 | |
| 2vcz | VC3 | Hematopoietic prostaglandin D synthase | / | 0.461 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.461 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.461 | |
| 3b05 | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.461 | |
| 3cqu | CQU | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.461 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.461 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.461 | |
| 3hqd | ANP | Kinesin-like protein KIF11 | / | 0.461 | |
| 3kdt | 7HA | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 3ql3 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 3zk6 | H1I | Bcl-2-like protein 1 | / | 0.461 | |
| 4l3q | 926 | Glucokinase | 2.7.1.2 | 0.461 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.460 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.460 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.460 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 2eka | SAH | Diphthine synthase | / | 0.460 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 2pda | TPP | Pyruvate synthase | / | 0.460 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2xf0 | 4UB | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.460 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 4du6 | GTP | GTP cyclohydrolase 1 | / | 0.460 | |
| 4kwh | NAP | Reductase homolog | / | 0.460 | |
| 4nbh | 9CA | Terminal oxygenase component of carbazole | / | 0.460 | |
| 1k4h | APQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.459 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.459 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.459 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.459 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.459 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.459 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.459 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.459 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.458 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.458 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 2clf | F6F | Tryptophan synthase alpha chain | / | 0.458 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.458 | |
| 2ewa | SB2 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.458 | |
| 3eku | CY9 | Actin-5C | / | 0.458 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.458 | |
| 4hqv | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.458 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.458 | |
| 5c7h | NDP | Putative oxidoreductase | / | 0.458 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.457 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1n5v | NOM | ActVA 6 protein | / | 0.457 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.457 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.457 | |
| 3gki | CLR | Niemann-Pick C1 protein | / | 0.457 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.457 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.457 | |
| 4kfj | 1R0 | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4nbb | 9CA | Terminal oxygenase component of carbazole | / | 0.457 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 4tzt | 468 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.457 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.457 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.457 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.456 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.456 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.456 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.456 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.456 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.456 | |
| 3ele | PLP | Aminotransferase | / | 0.456 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.456 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.456 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.456 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.456 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.456 | |
| 4odo | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.456 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.456 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.455 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.455 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.455 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.455 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.455 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.455 | |
| 1u2g | APR | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.455 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.455 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.455 | |
| 2e8q | SAH | Diphthine synthase | / | 0.455 | |
| 2gby | BRN | HTH-type transcriptional regulator QacR | / | 0.455 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.455 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.455 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.455 | |
| 2pck | SAH | Diphthine synthase | / | 0.455 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.455 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.455 | |
| 3q8h | AO9 | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.455 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.455 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.455 | |
| 4f7i | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.455 | |
| 4g34 | 924 | Eukaryotic translation initiation factor 2-alpha kinase 3 | 2.7.11.1 | 0.455 | |
| 4hyf | 1AK | Tankyrase-2 | 2.4.2.30 | 0.455 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.455 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.455 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.455 | |
| 4qmt | H1N | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.455 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.454 | |
| 1n3s | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.454 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.454 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.454 | |
| 2i62 | SAH | Nicotinamide N-methyltransferase | 2.1.1.1 | 0.454 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.454 | |
| 2qe2 | 452 | Polyprotein | / | 0.454 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.454 | |
| 3cth | 319 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.454 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.454 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.454 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.454 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.454 | |
| 4b5o | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.454 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.454 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.454 | |
| 1cbr | REA | Cellular retinoic acid-binding protein 1 | / | 0.453 | |
| 1ftl | DNQ | Glutamate receptor 2 | / | 0.453 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.453 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.453 | |
| 1pt8 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.453 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 2b04 | CHO | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.453 | |
| 2bvs | 2CE | Prothrombin | 3.4.21.5 | 0.453 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.453 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.453 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.453 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.453 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.453 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.453 | |
| 3up0 | D7S | aceDAF-12 | / | 0.453 | |
| 4azw | ATP | O-antigen chain terminator bifunctional methyltransferase/kinase WbdD | / | 0.453 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.453 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4eev | L1X | Hepatocyte growth factor receptor | 2.7.10.1 | 0.453 | |
| 4ft5 | H2K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 4iae | 1DX | Alr2278 protein | / | 0.453 | |
| 5d7o | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.453 | |
| 5epv | ACP | Blue-light-activated histidine kinase | 2.7.13.3 | 0.453 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.452 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.452 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.452 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.452 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 3p9t | TCL | Repressor | / | 0.452 | |
| 3t5i | SER_SER_CMT_FAR | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.452 | |
| 3t7v | SAM | 3-methylornithine synthase | / | 0.452 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.452 | |
| 4iwc | 1GV | Estrogen receptor | / | 0.452 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.452 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.452 | |
| 4ykf | NAI | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.452 | |
| 5d7q | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.452 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.452 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.452 | |
| 1ivr | CBA | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.451 | |
| 1jdz | FMB | Purine nucleoside phosphorylase | / | 0.451 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.451 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.451 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.451 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.451 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.451 | |
| 1yc2 | NAD | NAD-dependent protein deacylase 2 | / | 0.451 | |
| 2acl | L05 | Oxysterols receptor LXR-alpha | / | 0.451 | |
| 2cul | FAD | GidA-related protein | / | 0.451 | |
| 2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2v3h | I25 | Prothrombin | 3.4.21.5 | 0.451 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.451 | |
| 3bld | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.451 | |
| 3e5a | VX6 | Aurora kinase A | 2.7.11.1 | 0.451 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.451 | |
| 3hv3 | R49 | Mitogen-activated protein kinase 14 | / | 0.451 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.451 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.451 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.451 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.451 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.451 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.451 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4zhi | ADP | Kinesin-like protein KIF11 | / | 0.451 | |
| 5d7q | 4I5 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.451 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.451 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.450 | |
| 1ry0 | PG2 | Aldo-keto reductase family 1 member C3 | / | 0.450 | |
| 1srf | MTB | Streptavidin | / | 0.450 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.450 | |
| 1uwh | BAX | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.450 | |
| 1ybg | TAV | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.450 | |
| 2hzq | STR | Apolipoprotein D | / | 0.450 | |
| 2pir | DHT | Androgen receptor | / | 0.450 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.450 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.450 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.450 | |
| 2x9v | TMQ | Pteridine reductase | / | 0.450 | |
| 2z1w | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.450 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3uic | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.450 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.450 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.450 | |
| 4bmp | FMN | Protein NrdI | / | 0.450 | |
| 4hsh | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.450 | |
| 4k6i | 9RA | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.450 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.450 | |
| 4tta | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.449 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.449 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.449 | |
| 1n8w | COA | Malate synthase G | / | 0.449 | |
| 1oyt | FSN | Prothrombin | 3.4.21.5 | 0.449 | |
| 1syn | F89 | Thymidylate synthase | / | 0.449 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1y6q | TDI | 5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase | 3.2.2.9 | 0.449 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.449 | |
| 2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.449 | |
| 2olc | ADP | Methylthioribose kinase | 2.7.1.100 | 0.449 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.449 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.449 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.449 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.449 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.449 | |
| 3e8x | NAP | BH1520 protein | / | 0.449 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3occ | DIH | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.449 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.449 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.449 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.449 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.449 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.449 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.449 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.449 | |
| 4y6g | F6F | Tryptophan synthase alpha chain | / | 0.449 | |
| 1dtp | APU | Diphtheria toxin | / | 0.448 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.448 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.448 | |
| 1ne4 | RP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.448 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.448 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2emu | SAH | Diphthine synthase | / | 0.448 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2p5c | SAH | Diphthine synthase | / | 0.448 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.448 | |
| 3hz6 | ADP | Xylulokinase | / | 0.448 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.448 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4c6z | TLE | 3-oxoacyl-ACP synthase | / | 0.448 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.448 | |
| 4gcx | PRF | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.448 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.448 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.448 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.448 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.448 | |
| 5bu2 | ADP | Uncharacterized protein | / | 0.448 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.448 | |
| 5d7p | OCZ | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.448 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.448 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.447 | |
| 1dlr | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.447 | |
| 1pnq | NDP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.447 | |
| 1qip | GNB | Lactoylglutathione lyase | 4.4.1.5 | 0.447 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.447 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.447 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.447 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.447 | |
| 2e8h | SAH | Diphthine synthase | / | 0.447 | |
| 2fyu | FDN | Cytochrome b | / | 0.447 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.447 | |
| 2oci | TYC | Valacyclovir hydrolase | 3.1 | 0.447 | |
| 2q61 | SF1 | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 2vi5 | Y19 | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2wmt | ZYT | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.447 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3b03 | VNR | Isopentenyl-diphosphate delta-isomerase | / | 0.447 | |
| 3eks | CY9 | Actin-5C | / | 0.447 | |
| 3ew2 | BTN | Hypothetical conserved protein | / | 0.447 | |
| 3f82 | 353 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.447 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.447 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.447 | |
| 4g6n | EK0 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.447 | |
| 1dr4 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.446 | |
| 1f3e | DPZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.446 | |
| 1mma | ADP | Myosin-2 heavy chain | / | 0.446 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.446 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.446 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.446 | |
| 2dsh | SAH | Diphthine synthase | / | 0.446 | |
| 2dwb | ANP | Aurora kinase A | 2.7.11.1 | 0.446 | |
| 2e07 | SAH | Diphthine synthase | / | 0.446 | |
| 2e7r | SAH | Diphthine synthase | / | 0.446 | |
| 2h23 | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.446 | |
| 2p1t | 3TN | Retinoic acid receptor RXR-alpha | / | 0.446 | |
| 2p2x | SAH | Diphthine synthase | / | 0.446 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.446 | |
| 2zhf | 49U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.446 | |
| 3c1o | NAP | Eugenol synthase | / | 0.446 | |
| 3g2l | LEW | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.446 | |
| 3up3 | XCA | aceDAF-12 | / | 0.446 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.446 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.446 | |
| 4cby | KEE | Histone deacetylase 4 | 3.5.1.98 | 0.446 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.446 | |
| 4elb | 34S | Dihydrofolate reductase | / | 0.446 | |
| 4hvx | QEI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.446 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.446 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.446 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.446 | |
| 4qii | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.446 | |
| 4rel | KMP | Glycosyltransferase | / | 0.446 | |
| 4zqc | F6F | Tryptophan synthase alpha chain | / | 0.446 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.446 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.445 | |
| 1dd6 | MCI | Metallo-beta-lactamase type 2 | / | 0.445 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.445 | |
| 1jxz | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.445 | |
| 1n2v | BDI | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.445 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1pr6 | XYA | Purine nucleoside phosphorylase DeoD-type | / | 0.445 | |
| 1ptj | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.445 | |
| 1srj | NAB | Streptavidin | / | 0.445 | |
| 1uhh | CZP | Aequorin-2 | / | 0.445 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.445 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.445 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.445 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.445 | |
| 2bxq | IMN | Serum albumin | / | 0.445 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.445 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.445 | |
| 2p9d | SAH | Diphthine synthase | / | 0.445 | |
| 2wtk | ANP | STE20-related kinase adapter protein alpha | / | 0.445 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 2z52 | H23 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.445 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.445 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.445 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.445 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.445 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.445 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.445 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.445 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.445 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.445 | |
| 4af6 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.445 | |
| 4ft7 | H3K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 5d7p | AR6 | NAD-dependent protein deacetylase sirtuin-2 | 3.5.1 | 0.445 | |
| 5kf2 | ACO | Predicted acetyltransferase | / | 0.445 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.445 | |
| 4ug2 | NGI | Adenosine receptor A2a | / | 0.445 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 1dr5 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1fgi | SU1 | Fibroblast growth factor receptor 1 | / | 0.444 | |
| 1kmq | GNP | Transforming protein RhoA | / | 0.444 | |
| 1kuy | COT | Serotonin N-acetyltransferase | / | 0.444 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.444 | |
| 1pu9 | COA | HAT A1 | / | 0.444 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.444 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.444 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.444 | |
| 1y5x | E89 | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.444 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2dxx | SAH | Diphthine synthase | / | 0.444 | |
| 2eh4 | SAH | Diphthine synthase | / | 0.444 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 2hm9 | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 2huq | SAH | Diphthine synthase | / | 0.444 | |
| 2jh6 | 894 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2oh4 | GIG | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.444 | |
| 2vet | UMP | Thymidylate synthase | / | 0.444 | |
| 2yat | EEU | Estrogen receptor | / | 0.444 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.444 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3c72 | CX1 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3ipu | O40 | Oxysterols receptor LXR-alpha | / | 0.444 | |
| 3x0a | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 4gtt | 7TQ | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.444 | |
| 4hmb | PZZ | Phospholipase A2 VRV-PL-VIIIa | / | 0.444 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.444 | |
| 4li8 | 1XQ | Tankyrase-1 | 2.4.2.30 | 0.444 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.444 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.444 | |
| 5i2h | AGI | O-methyltransferase family 2 | / | 0.444 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
| 1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1ga8 | UPF | LgtC | / | 0.443 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.443 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1xr2 | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase | 2.1.1.14 | 0.443 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.443 | |
| 2b35 | TCL | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2egl | SAH | Diphthine synthase | / | 0.443 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.443 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.443 | |
| 2hps | CTZ | Ca2+-triggered coelenterazine-binding protein 1 | / | 0.443 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.443 | |
| 2ojg | 19A | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.443 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2qe4 | JJ3 | Estrogen receptor | / | 0.443 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.443 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.443 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 2zsc | BTN | Tamavidin2 | / | 0.443 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3b04 | OOP | Isopentenyl-diphosphate delta-isomerase | / | 0.443 | |
| 3b8q | 900 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 3gc5 | 2MQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 3gcq | 1BU | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3kxo | KXO | Hematopoietic prostaglandin D synthase | / | 0.443 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.443 | |
| 3vi5 | M4M | Hematopoietic prostaglandin D synthase | / | 0.443 | |
| 4biw | ANP | Sensor histidine kinase CpxA | / | 0.443 | |
| 4ea2 | RWZ | Dehydrosqualene synthase | / | 0.443 | |
| 4eix | NIM | Phospholipase A2 VRV-PL-VIIIa | / | 0.443 | |
| 4fhb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 4gg9 | 0WW | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.443 | |
| 4k7a | DHT | Androgen receptor | / | 0.443 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.443 | |
| 1d4p | BPP | Prothrombin | 3.4.21.5 | 0.442 | |
| 1dhf | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.442 | |
| 1lv8 | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1nbm | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.442 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.442 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.442 | |
| 1xuo | LA1 | Integrin alpha-L | / | 0.442 | |
| 2cle | F6F | Tryptophan synthase alpha chain | / | 0.442 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2jdc | CAO | Probable acetyltransferase | / | 0.442 | |
| 2jdd | ACO | Probable acetyltransferase | / | 0.442 | |
| 2pk3 | GDD | GDP-6-deoxy-D-mannose reductase | / | 0.442 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2wjo | QUD | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.442 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.442 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.442 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.442 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.442 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.442 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.442 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.442 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.442 | |
| 4gi4 | 0EX | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 4hvs | 647 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.442 | |
| 4mt9 | 2D6 | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.442 | |
| 4q15 | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.442 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4xoi | GTP | Transforming protein RhoA | / | 0.442 | |
| 4zn7 | DES | Estrogen receptor | / | 0.442 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.442 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.442 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.441 | |
| 1n83 | CLR | Nuclear receptor ROR-alpha | / | 0.441 | |
| 1pua | COA | HAT A1 | / | 0.441 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 2c31 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.441 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.441 | |
| 2k5t | COA | PanD regulatory factor | / | 0.441 | |
| 2nr4 | FMN | Conserved protein | / | 0.441 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.441 | |
| 2xvw | 9NR | Serum albumin | / | 0.441 | |
| 2zhw | 12U | Prothrombin | 3.4.21.5 | 0.441 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.441 | |
| 3d73 | NBB | Pheromone-binding protein ASP1 | / | 0.441 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3g0e | B49 | Mast/stem cell growth factor receptor Kit | 2.7.10.1 | 0.441 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.441 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.441 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.441 | |
| 4i1n | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.441 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.441 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.441 | |
| 4z63 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.441 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.441 | |
| 5kgj | ACO | Predicted acetyltransferase | / | 0.441 | |
| 4py0 | 6AT | P2Y purinoceptor 12 | / | 0.441 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.441 | |
| 1a4i | NDP | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.440 | |
| 1bcu | PRL | Prothrombin | 3.4.21.5 | 0.440 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.440 | |
| 1kru | IPT | Galactoside O-acetyltransferase | 2.3.1.18 | 0.440 | |
| 1rfq | LAR | Actin, alpha skeletal muscle | / | 0.440 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.440 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.440 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.440 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.440 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.440 | |
| 3gqz | GF7 | Beta-lactamase | 3.5.2.6 | 0.440 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.440 | |
| 3qdz | PRO_ALA_PRO_ARG | Prothrombin | 3.4.21.5 | 0.440 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.440 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.440 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 4boe | CLR | Japanin | / | 0.440 | |
| 4dlb | NAD | S-(hydroxymethyl)glutathione dehydrogenase | / | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4edy | 9PQ | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4tqq | UQ1 | Reaction center protein L chain | / | 0.440 | |
| 4umy | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 4uxq | 0LI | Fibroblast growth factor receptor 4 | 2.7.10.1 | 0.440 |