sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 1.000 | |
| 4zz6 | CTP | Ribosome inactivating protein | / | 0.577 | |
| 3u8f | FGM | Ribosome inactivating protein | / | 0.562 | |
| 4jtp | ASC | Ribosome inactivating protein | / | 0.549 | |
| 4lwx | MU2 | Ribosome inactivating protein | / | 0.547 | |
| 4emr | MGP | Ribosome inactivating protein | / | 0.545 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.523 | |
| 1lpc | CMP | Antiviral protein DAP-30 | 3.2.2.22 | 0.522 | |
| 3qji | MGP | Ribosome inactivating protein | / | 0.516 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.507 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.502 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.498 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.498 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.496 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.494 | |
| 3eku | CY9 | Actin-5C | / | 0.492 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.490 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.489 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.488 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.488 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.487 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.487 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.487 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.486 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.485 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.485 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.485 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.485 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.484 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.484 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.484 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.484 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.484 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.483 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.483 | |
| 3pft | FMN | Flavin reductase | / | 0.483 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.482 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.482 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.482 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.481 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.481 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.481 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.480 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.480 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.480 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.479 | |
| 1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.478 | |
| 1yzq | GNP | Ras-related protein Rab-6A | / | 0.478 | |
| 1qcj | APT | Antiviral protein I | 3.2.2.22 | 0.477 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.477 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.476 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.476 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.476 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.476 | |
| 2r5n | TPP | Transketolase 1 | / | 0.476 | |
| 3c14 | FOK | Adenylate cyclase type 2 | / | 0.476 | |
| 3c14 | FOK | Adenylate cyclase type 5 | / | 0.476 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.476 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.474 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.474 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.474 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.474 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.474 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 4e2d | FMN | Dehydrogenase | / | 0.474 | |
| 4u0s | ADP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.474 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.474 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.473 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.473 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.473 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.473 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.472 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.472 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.471 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.471 | |
| 2fx2 | FMN | Flavodoxin | / | 0.471 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.471 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.470 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.470 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.470 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.470 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.470 | |
| 1uoo | GLY_PHE_ARG_PRO | Prolyl endopeptidase | 3.4.21.26 | 0.469 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.468 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.468 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.468 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 4acu | QN7 | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.467 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.467 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.467 | |
| 1tkc | M6T | Transketolase 1 | 2.2.1.1 | 0.467 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.467 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.467 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.467 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.467 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.466 | |
| 3gn7 | 3GN | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.466 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.466 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.466 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.466 | |
| 4gcm | NAP | Thioredoxin reductase | 1.8.1.9 | 0.466 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.465 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.465 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.465 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.465 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.465 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.465 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.465 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.465 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.464 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.464 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.464 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.464 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.463 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.463 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.463 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.463 | |
| 2rd2 | QSI | Glutamine--tRNA ligase | 6.1.1.18 | 0.463 | |
| 2v95 | HCY | Corticosteroid-binding globulin | / | 0.463 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.462 | |
| 3v2u | ATP | Protein GAL3 | / | 0.462 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.462 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.462 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.462 | |
| 5la6 | GDP | Tubulin beta-2B chain | / | 0.462 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.461 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.461 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.461 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.461 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3bbp | GTP | Ras-related protein Rab-6A | / | 0.461 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.461 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.461 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.461 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.460 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 2cv1 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.460 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.460 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.460 | |
| 4e2b | FMN | Dehydrogenase | / | 0.460 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.460 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.460 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.459 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.459 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.459 | |
| 2qta | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.459 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.459 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.459 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.459 | |
| 4f6r | GDP | Tubulin beta chain | / | 0.459 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 4l2z | S7M | S-adenosylmethionine synthase | / | 0.459 | |
| 4rnv | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.459 | |
| 4twr | NAD | NAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase | / | 0.459 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.459 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.458 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.458 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.458 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.458 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.458 | |
| 3eks | CY9 | Actin-5C | / | 0.458 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.458 | |
| 4ubt | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.458 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.458 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.457 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.457 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.457 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.457 | |
| 3nzp | PLP | Arginine decarboxylase | / | 0.457 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.457 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.457 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.457 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.456 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.456 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.456 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.456 | |
| 1xqp | 8HG | N-glycosylase/DNA lyase | / | 0.456 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.456 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.456 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.456 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.456 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.456 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.456 | |
| 2y99 | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.456 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.456 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.456 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.456 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.455 | |
| 1w88 | TDP | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.455 | |
| 1w88 | TDP | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.455 | |
| 1wsb | FMN | Flavodoxin | / | 0.455 | |
| 1xh7 | R96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 2c31 | TZD | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.455 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.455 | |
| 3ehe | NAD | UDP-glucose 4-epimerase (GalE-1) | / | 0.455 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.455 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.455 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.455 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.455 | |
| 1ahb | FMP | Ribosome-inactivating protein momordin I | 3.2.2.22 | 0.454 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.454 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.454 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.454 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.454 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.454 | |
| 3f6s | FMN | Flavodoxin | / | 0.454 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.454 | |
| 4hh4 | SAH | CcbJ | / | 0.454 | |
| 4ikz | AFS | Di-tripeptide ABC transporter (Permease) | / | 0.454 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.454 | |
| 1kw6 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.453 | |
| 1ppj | ANY | Cytochrome b | / | 0.453 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.453 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.453 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3bj8 | COA | Diamine acetyltransferase 1 | / | 0.453 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3sfx | JAN | Uncharacterized protein | / | 0.453 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.453 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.453 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.453 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.453 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.453 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.453 | |
| 1j0d | 5PA | 1-aminocyclopropane-1-carboxylate deaminase | 3.5.99.7 | 0.452 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.452 | |
| 2pca | SAH | Diphthine synthase | / | 0.452 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.452 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.452 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.452 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3lnc | 5GP | Guanylate kinase | / | 0.452 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.452 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.452 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.452 | |
| 4bmp | FMN | Protein NrdI | / | 0.452 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.452 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 1osv | CHC | Bile acid receptor | / | 0.451 | |
| 1t91 | GTP | Ras-related protein Rab-7a | / | 0.451 | |
| 1tys | TMP | Thymidylate synthase | / | 0.451 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.451 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2d8a | NAD | L-threonine 3-dehydrogenase | / | 0.451 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.451 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.451 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.451 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.451 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.451 | |
| 4j1h | 1HJ | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.451 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.451 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.451 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.450 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.450 | |
| 1ni4 | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.450 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.450 | |
| 1p3d | UMA | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.450 | |
| 1rp7 | TZD | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.450 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.450 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 2bpo | NAP | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.450 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.450 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.450 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.450 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.450 | |
| 4e2x | TYD | Methyltransferase | / | 0.450 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.450 | |
| 4jic | FMN | GTN Reductase | / | 0.450 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.450 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.450 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.450 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.449 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.449 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.449 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.449 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.449 | |
| 3doc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.449 | |
| 3k5d | XLI | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.449 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.449 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.449 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1e0j | ANP | DNA primase/helicase | 2.7.7 | 0.448 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1i75 | NOJ | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.448 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.448 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.448 | |
| 1vf2 | GTX | Glutathione S-transferase 3 | 2.5.1.18 | 0.448 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.448 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.448 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.448 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.448 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.448 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.448 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.448 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.447 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.447 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.447 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.447 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2vb8 | TLM | 3-oxoacyl-[acyl-carrier-protein] synthase 1 | 2.3.1.41 | 0.447 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.447 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.447 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.447 | |
| 3p5p | A3C | Taxadiene synthase | 4.2.3.17 | 0.447 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3zl8 | ADP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.447 | |
| 4j0z | 1H5 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4l96 | LRG | Peroxisome proliferator-activated receptor gamma | / | 0.447 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.447 | |
| 4xr9 | NAD | CalS8 | / | 0.447 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.447 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.447 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1zdw | FLV | Prenyltransferase | / | 0.446 | |
| 2cbr | A80 | Cellular retinoic acid-binding protein 1 | / | 0.446 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 2ov2 | GCP | Ras-related C3 botulinum toxin substrate 3 | / | 0.446 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 3dh7 | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.446 | |
| 3ndj | JHZ | Methyltransferase | / | 0.446 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.446 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.446 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.446 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.446 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 4j7h | TRH | PCZA361.3 | / | 0.446 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.446 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.445 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1l8a | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.445 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.445 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.445 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 2d1n | FA4 | Collagenase 3 | 3.4.24 | 0.445 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.445 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.445 | |
| 2j5b | TYE | Tyrosine--tRNA ligase | 6.1.1.1 | 0.445 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 2r8p | T6F | Transketolase 1 | / | 0.445 | |
| 2we3 | DUT | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.445 | |
| 2zdv | 37U | Prothrombin | 3.4.21.5 | 0.445 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.445 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.445 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.445 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 4bah | MEL | Prothrombin | 3.4.21.5 | 0.445 | |
| 4baq | M4Z | Prothrombin | 3.4.21.5 | 0.445 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.445 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.445 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.445 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.445 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.445 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.445 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.444 | |
| 1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.444 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 2nmt | NHM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.444 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.444 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.444 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.444 | |
| 3iex | GMP | Purine nucleoside phosphorylase | / | 0.444 | |
| 3k8o | 229 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.444 | |
| 3mzt | TFX | Beta-2-microglobulin | / | 0.444 | |
| 3pym | NAD | Glyceraldehyde-3-phosphate dehydrogenase 3 | 1.2.1.12 | 0.444 | |
| 3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4b1c | 1B1 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.444 | |
| 4bqw | QNM | Egl nine homolog 1 | / | 0.444 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 4hxy | NDP | Plm1 | / | 0.444 | |
| 4phl | PIL | Phosphodiesterase | / | 0.444 | |
| 5eso | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.444 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.443 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 1gaw | FAD | Ferredoxin | / | 0.443 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.443 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.443 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.443 | |
| 1njj | ORX | Ornithine decarboxylase | / | 0.443 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.443 | |
| 2bqz | SAH | N-lysine methyltransferase KMT5A | / | 0.443 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.443 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.443 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.443 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.443 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.443 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.443 | |
| 3ftx | RE2 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.443 | |
| 3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3hl4 | CDC | Choline-phosphate cytidylyltransferase A | / | 0.443 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 3qvi | K95 | HAP protein | / | 0.443 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.443 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.443 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.443 | |
| 4ha6 | PXM | Pyridoxine 4-oxidase | / | 0.443 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.443 | |
| 4l7v | SAH | Protein-L-isoaspartate O-methyltransferase | / | 0.443 | |
| 4zgs | NAD | Putative D-lactate dehydrogenase | / | 0.443 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.442 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.442 | |
| 2hpv | FMN | FMN-dependent NADH-azoreductase | 1.7 | 0.442 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.442 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.442 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.442 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.442 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2y3r | TIR | TamL | / | 0.442 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.442 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.442 | |
| 3ipk | PMS | Surface protein adhesin | / | 0.442 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.442 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.442 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.442 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.442 | |
| 4fpy | 0V8 | Sialidase B | 3.2.1.18 | 0.442 | |
| 4fui | UI3 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.442 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.442 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.442 | |
| 4mx1 | 1MX | Ricin | 3.2.2.22 | 0.442 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 1o0d | 163 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1rct | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1rz1 | NAD | Phenol 2-hydroxylase component B | / | 0.441 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.441 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 2b99 | RDL | Riboflavin synthase | 2.5.1.9 | 0.441 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.441 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.441 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.441 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3b9l | AZZ | Serum albumin | / | 0.441 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.441 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.441 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.441 | |
| 3h0b | B35 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.441 | |
| 3l7g | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.441 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.441 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.441 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.441 | |
| 3sff | 0DI | Histone deacetylase 8 | 3.5.1.98 | 0.441 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 3uyl | TYD | Probable NDP-rhamnosyltransferase | / | 0.441 | |
| 3vkj | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.441 | |
| 4blr | UTP | NTPase P4 | / | 0.441 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4isu | IKM | Glutamate receptor 2 | / | 0.441 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.441 | |
| 4lm4 | JPZ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4rnx | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.441 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.440 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.440 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.440 | |
| 1e2n | RCA | Thymidine kinase | / | 0.440 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.440 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.440 | |
| 1ulb | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 2g9r | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.440 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.440 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.440 | |
| 2ol0 | DUD | DUTP pyrophosphatase | / | 0.440 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.440 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.440 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.440 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.440 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.440 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.440 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.440 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3tfy | MET_LEU_GLY_PRO | N-alpha-acetyltransferase 50 | 2.3.1 | 0.440 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.440 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.440 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.440 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.440 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.440 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.440 |