sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4bqt | C5E | Soluble acetylcholine receptor |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4bqt | C5E | Soluble acetylcholine receptor | / | 1.000 | |
| 5ain | QMR | Soluble acetylcholine receptor | / | 0.604 | |
| 2xyt | TC9 | Soluble acetylcholine receptor | / | 0.541 | |
| 4alx | IZN | Acetylcholine-binding protein | / | 0.517 | |
| 1jtu | LYB | Thymidylate synthase | / | 0.514 | |
| 2xnv | VU3 | Soluble acetylcholine receptor | / | 0.510 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.503 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.499 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.497 | |
| 3zdh | XRS | Acetylcholine-binding protein | / | 0.496 | |
| 3l9m | L9M | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.495 | |
| 4b5d | SW4 | Achbp | / | 0.493 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.492 | |
| 3wtj | TH4 | Acetylcholine-binding protein | / | 0.492 | |
| 3zdg | XRX | Acetylcholine-binding protein | / | 0.491 | |
| 4f32 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | / | 0.490 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.488 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.487 | |
| 3kmy | D8Y | Beta-secretase 1 | 3.4.23.46 | 0.487 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.486 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.486 | |
| 4hhy | 15R | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.486 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.485 | |
| 3w78 | CBD | FMN-dependent NADH-azoreductase | / | 0.485 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.485 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.484 | |
| 3u8m | 09R | Acetylcholine-binding protein | / | 0.484 | |
| 4gxs | 0YS | Glutamate receptor 2 | / | 0.482 | |
| 5dqr | FAD | 7-hydroxymethyl chlorophyll a reductase, chloroplastic | 1.17.7.2 | 0.482 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.481 | |
| 2q5q | KPV | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.481 | |
| 3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.481 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.481 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.481 | |
| 2xlt | NA0 | Putative flavin-containing monooxygenase | / | 0.480 | |
| 2zi2 | 24U | Prothrombin | 3.4.21.5 | 0.480 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.480 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.480 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.480 | |
| 4hhz | 15S | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.480 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.479 | |
| 3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.479 | |
| 4o7u | THF | Thymidylate synthase | / | 0.479 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.479 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.478 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.478 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.477 | |
| 2fgk | ATP | Alpha-hemolysin translocation ATP-binding protein HlyB | / | 0.476 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.476 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.476 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.475 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.475 | |
| 2ziq | 26U | Prothrombin | 3.4.21.5 | 0.475 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.475 | |
| 1zgy | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.474 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.474 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.474 | |
| 2ob0 | ACO | N-alpha-acetyltransferase 50 | / | 0.474 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 2w6q | OA5 | Biotin carboxylase | 6.3.4.14 | 0.472 | |
| 3bhr | THG | Thymidylate synthase | / | 0.472 | |
| 3wip | ACH | Acetylcholine-binding protein | / | 0.472 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.471 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.471 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.470 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.470 | |
| 3ihg | VAK | Aklavinone 12-hydroxylase RdmE | / | 0.469 | |
| 3l9n | L9N | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.469 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.469 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.469 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.469 | |
| 1cjw | COT | Serotonin N-acetyltransferase | / | 0.468 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.468 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.468 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.468 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.468 | |
| 4bqr | IBH | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.468 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.468 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.468 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.468 | |
| 1lke | DOG | Bilin-binding protein | / | 0.467 | |
| 1o5g | CR9 | Prothrombin | 3.4.21.5 | 0.467 | |
| 2zxg | S23 | Aminopeptidase N | 3.4.11.2 | 0.467 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.467 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.467 | |
| 3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.467 | |
| 1g3m | PCQ | Estrogen sulfotransferase | 2.8.2.4 | 0.466 | |
| 1k7f | IAV | Tryptophan synthase alpha chain | / | 0.466 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.466 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.466 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.466 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.466 | |
| 4nv1 | TYD | Formyl transferase | / | 0.466 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.465 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3zv6 | 4HB | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.465 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.465 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.464 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.464 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.464 | |
| 2xj2 | 985 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 2zhe | 13U | Prothrombin | 3.4.21.5 | 0.464 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.464 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.464 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.464 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.463 | |
| 2pr2 | DG1 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.463 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.463 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.463 | |
| 3eku | CY9 | Actin-5C | / | 0.462 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 3ime | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.462 | |
| 4jaz | STL | Peroxisome proliferator-activated receptor gamma | / | 0.462 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.461 | |
| 1sb1 | 165 | Prothrombin | 3.4.21.5 | 0.461 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.461 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 2h9i | EAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 4a6a | TTP | dCTP deaminase | 3.5.4.13 | 0.461 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.461 | |
| 4hcy | 0YN | Transketolase | / | 0.461 | |
| 4rri | A3T | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.461 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.461 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.460 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.460 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.460 | |
| 2w02 | ATP | AcsD | / | 0.460 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.460 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3kek | 3EK | Collagenase 3 | 3.4.24 | 0.460 | |
| 3s7d | LEU_SER_LYS_LYS_MLZ | N-lysine methyltransferase SMYD2 | / | 0.460 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.460 | |
| 2mm3 | CHO | Gastrotropin | / | 0.459 | |
| 2qbs | 024 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.459 | |
| 2znk | 31U | Prothrombin | 3.4.21.5 | 0.459 | |
| 3cso | XNI | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.459 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.459 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.459 | |
| 1bwk | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.458 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.458 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.458 | |
| 1ypj | UIB | Prothrombin | 3.4.21.5 | 0.458 | |
| 2zda | 32U | Prothrombin | 3.4.21.5 | 0.458 | |
| 2zf0 | 51U | Prothrombin | 3.4.21.5 | 0.458 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.458 | |
| 3oht | 1N1 | Mitogen-activated protein kinase | / | 0.458 | |
| 4afg | QMR | Achbp | / | 0.458 | |
| 1axw | MTX | Thymidylate synthase | / | 0.457 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.457 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.457 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1q83 | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2d81 | RB3 | Poly(3-hydroxybutyrate) depolymerase | / | 0.457 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.457 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.457 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.457 | |
| 3biu | 10U | Prothrombin | 3.4.21.5 | 0.457 | |
| 3bnk | FMN | Flavoredoxin | / | 0.457 | |
| 4dw6 | 0MN | HTH-type transcriptional regulator EthR | / | 0.457 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.457 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.456 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.456 | |
| 2x3j | ATP | AcsD | / | 0.456 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.456 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.456 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.456 | |
| 4kxj | P34 | Nucleoprotein | / | 0.456 | |
| 3d4s | TIM | Beta-2 adrenergic receptor | / | 0.456 | |
| 1kqb | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.455 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.455 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.455 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.455 | |
| 2y02 | WHJ | Beta-1 adrenergic receptor | / | 0.455 | |
| 2y6d | TQJ | Matrilysin | 3.4.24.23 | 0.455 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.455 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.455 | |
| 3dv0 | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.455 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.455 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.455 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4ige | CHJ | Enoyl-acyl carrier reductase | / | 0.455 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.455 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.455 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.455 | |
| 2y04 | 68H | Beta-1 adrenergic receptor | / | 0.455 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.454 | |
| 1fml | RTL | Retinol dehydratase | / | 0.454 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3hy7 | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.454 | |
| 3u9n | 09H | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4a4w | YFB | Peroxisome proliferator-activated receptor gamma | / | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.454 | |
| 4iqq | D16 | Thymidylate synthase | / | 0.454 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.454 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.454 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.453 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.453 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.453 | |
| 3b9l | AZZ | Serum albumin | / | 0.453 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.453 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.453 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.453 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.453 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.453 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.453 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.453 | |
| 4trn | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.453 | |
| 5ios | FAD | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.453 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.452 | |
| 1f0l | APU | Diphtheria toxin | / | 0.452 | |
| 2w6m | OA1 | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.452 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4kfp | 1R7 | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.452 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.452 | |
| 1dqa | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.451 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 1lce | TMF | Thymidylate synthase | / | 0.451 | |
| 1nhw | TCC | Enoyl-ACP reductase | / | 0.451 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 2anm | CDO | Prothrombin | 3.4.21.5 | 0.451 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 2w6o | OA3 | Biotin carboxylase | 6.3.4.14 | 0.451 | |
| 3cow | 52H | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.451 | |
| 3gbk | 2PQ | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.451 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3wav | DWV | Ectonucleotide pyrophosphatase/phosphodiesterase family member 2 | 3.1.4.39 | 0.451 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.451 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4hyi | 1AO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4m5p | FMN | NADPH dehydrogenase | / | 0.451 | |
| 5hyn | SAH | Histone-lysine N-methyltransferase EZH2 | 2.1.1.43 | 0.451 | |
| 7kme | ACE_0BN_CHG_PRR | Prothrombin | 3.4.21.5 | 0.451 | |
| 2rh1 | CAU | Beta-2 adrenergic receptor | / | 0.451 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1ogi | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.450 | |
| 1ta6 | 177 | Prothrombin | 3.4.21.5 | 0.450 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.450 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.450 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3ama | SKE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 3iod | A6D | Pantothenate synthetase | 6.3.2.1 | 0.450 | |
| 3pnd | FAD | FAD:protein FMN transferase | / | 0.450 | |
| 4bz8 | J38 | Histone deacetylase | / | 0.450 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.450 | |
| 4loh | 1SY | Stimulator of interferon genes protein | / | 0.450 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.450 | |
| 4u15 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.450 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1v0c | ACO | AAC(6')-Ib | / | 0.449 | |
| 2ath | 3EA | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2v5u | FMN | Flavodoxin | / | 0.449 | |
| 2xlr | NAP | Putative flavin-containing monooxygenase | / | 0.449 | |
| 2xnc | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.449 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.449 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.449 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3tif | ADP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.449 | |
| 3vmm | P0D | Alanine--anticapsin ligase | / | 0.449 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 4lww | LWW | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.449 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.449 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.449 | |
| 4ts7 | ADP | Purine phosphoribosyltransferase (GpT-1) | / | 0.449 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.449 | |
| 1h35 | R01 | Squalene--hopene cyclase | 4.2.1.129 | 0.448 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.448 | |
| 1m51 | TSX | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.448 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.448 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2h2a | DND | Probable nicotinate-nucleotide adenylyltransferase | / | 0.448 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2xlp | NAP | Putative flavin-containing monooxygenase | / | 0.448 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.448 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.448 | |
| 3te4 | ACO | Dopamine N-acetyltransferase | / | 0.448 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.448 | |
| 4fpy | 0V8 | Sialidase B | 3.2.1.18 | 0.448 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 4ra3 | TFX | Beta-2-microglobulin | / | 0.448 | |
| 3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.448 | |
| 1ddu | CB3 | Thymidylate synthase | / | 0.447 | |
| 1gj4 | 132 | Prothrombin | 3.4.21.5 | 0.447 | |
| 1go2 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.447 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.447 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.447 | |
| 1k22 | MEL | Prothrombin | 3.4.21.5 | 0.447 | |
| 1nsy | ATP | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.447 | |
| 1p0h | COA | Mycothiol acetyltransferase | 2.3.1.189 | 0.447 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1zrb | 062 | Prothrombin | 3.4.21.5 | 0.447 | |
| 2a4n | COA | Aac(6')-Ii protein | / | 0.447 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.447 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.447 | |
| 2xls | NAP | Putative flavin-containing monooxygenase | / | 0.447 | |
| 2zfq | 45U | Prothrombin | 3.4.21.5 | 0.447 | |
| 3h59 | H59 | Genome polyprotein | 2.7.7.48 | 0.447 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.447 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.447 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.447 | |
| 4yaf | FAD | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.447 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.447 | |
| 5bn3 | ADP | NEQ263 | / | 0.447 | |
| 1fds | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 1gjr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.446 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1qlt | FAD | Vanillyl-alcohol oxidase | 1.1.3.38 | 0.446 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 1xh8 | R55 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2e07 | SAH | Diphthine synthase | / | 0.446 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.446 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.446 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.446 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.446 | |
| 3wth | IM4 | Acetylcholine-binding protein | / | 0.446 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.446 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4ih6 | 1EP | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.446 | |
| 4lxb | 7R9 | Prothrombin | 3.4.21.5 | 0.446 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.446 | |
| 5ch7 | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.446 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.445 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1tys | DHF | Thymidylate synthase | / | 0.445 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.445 | |
| 2zju | IM4 | Acetylcholine-binding protein | / | 0.445 | |
| 3c1t | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 3fri | SAH | 16S rRNA methylase | / | 0.445 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.445 | |
| 3moh | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.445 | |
| 3vg1 | 0GT | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.445 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.445 | |
| 4bvn | P32 | Beta-1 adrenergic receptor | / | 0.445 | |
| 4co4 | ATP | Nitrogen regulatory protein P-II 1 | / | 0.445 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.445 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.445 | |
| 5dsy | UHB | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.445 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.444 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.444 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 2v19 | FMN | Dodecin | / | 0.444 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 3c6n | 2S8 | Protein TRANSPORT INHIBITOR RESPONSE 1 | / | 0.444 | |
| 3f6s | FMN | Flavodoxin | / | 0.444 | |
| 3fbc | TYD | Nucleoside diphosphate kinase | 2.7.4.6 | 0.444 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.444 | |
| 3gds | VAL_TYR_TYR_PHE | Serine endoprotease DegS | 3.4.21.107 | 0.444 | |
| 3hky | IX6 | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.444 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.444 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.444 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.444 | |
| 5dp2 | NAP | CurF | / | 0.444 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.444 | |
| 5f8u | P32 | Beta-1 adrenergic receptor | / | 0.444 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.443 | |
| 1fvp | FMA | Non-fluorescent flavoprotein | / | 0.443 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.443 | |
| 1n2i | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 1qzf | CB3 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.443 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.443 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1ypm | RA4 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.443 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.443 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.443 | |
| 2hpt | BES | Aminopeptidase N | 3.4.11.2 | 0.443 | |
| 2pda | TPP | Pyruvate synthase | / | 0.443 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.443 | |
| 3c49 | KU8 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.443 | |
| 3dux | 64U | Prothrombin | 3.4.21.5 | 0.443 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.443 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.443 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.443 | |
| 4acd | GR9 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.443 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4dyb | 0MH | Nucleoprotein | / | 0.443 | |
| 4jtr | IZP | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.443 | |
| 4l1x | STR | Aldo-keto reductase family 1 member C2 | / | 0.443 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.443 | |
| 4xnh | ACO | N-terminal acetyltransferase A complex subunit NAT5 | 2.3.1 | 0.443 | |
| 4ype | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.443 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.443 | |
| 1an5 | CB3 | Thymidylate synthase | / | 0.442 | |
| 1kqn | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1kzi | THG | Thymidylate synthase | / | 0.442 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.442 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.442 | |
| 2i4z | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.442 | |
| 2qcx | PF1 | Aminopyrimidine aminohydrolase | / | 0.442 | |
| 2xvv | 9DN | Serum albumin | / | 0.442 | |
| 2zc9 | 22U | Prothrombin | 3.4.21.5 | 0.442 | |
| 2zgx | 29U | Prothrombin | 3.4.21.5 | 0.442 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.442 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.442 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.442 | |
| 3rpn | GTX | Glutathione S-transferase kappa 1 | 2.5.1.18 | 0.442 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 3zv5 | BPY | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | 1.3.1.56 | 0.442 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.442 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.442 | |
| 4eyf | PNK | Metallo-beta-lactamase type 2 | / | 0.442 | |
| 4l5b | 1UX | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.442 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.442 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.442 | |
| 2ycy | P32 | Beta-1 adrenergic receptor | / | 0.442 | |
| 4lde | P0G | Beta-2 adrenergic receptor | / | 0.442 | |
| 3ny8 | JRZ | Beta-2 adrenergic receptor | / | 0.442 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.441 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.441 | |
| 1jf0 | CZH | Obelin | / | 0.441 | |
| 1mue | CDD | Prothrombin | 3.4.21.5 | 0.441 | |
| 1ozp | ACO | Mycothiol acetyltransferase | 2.3.1.189 | 0.441 | |
| 1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.441 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.441 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 1xm1 | GAH | Prothrombin | 3.4.21.5 | 0.441 | |
| 1y6o | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.441 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.441 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.441 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.441 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 2ie0 | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.441 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.441 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.441 | |
| 3bwc | SAM | Spermidine synthase, putative | / | 0.441 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.441 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.441 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3f90 | FMN | Flavodoxin | / | 0.441 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.441 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.441 | |
| 3r96 | ACO | MccE protein | / | 0.441 | |
| 3u9y | 09L | Tankyrase-2 | 2.4.2.30 | 0.441 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4fog | C2F | Thymidylate synthase ThyA | / | 0.441 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.441 | |
| 4um1 | 09P | Acetylcholine-binding protein | / | 0.441 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.441 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.441 | |
| 1f4f | TP3 | Thymidylate synthase | / | 0.440 | |
| 1k02 | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.440 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1pd8 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1pg2 | ADN | Methionine--tRNA ligase | 6.1.1.10 | 0.440 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
| 1q6n | P90 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.440 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2aot | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.440 | |
| 2bzs | CB1 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.440 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.440 | |
| 2hct | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.440 | |
| 2i4p | DRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2y01 | Y00 | Beta-1 adrenergic receptor | / | 0.440 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.440 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.440 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.440 | |
| 3o73 | O73 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.440 | |
| 3rdo | BTN | Streptavidin | / | 0.440 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4amj | CVD | Beta-1 adrenergic receptor | / | 0.440 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.440 | |
| 4c67 | L5S | Bromodomain-containing protein 4 | / | 0.440 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.440 | |
| 4i12 | 1BC | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.440 | |
| 4ozn | ATP | Ammonium transporter | / | 0.440 |