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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3vaxPLPUncharacterized protein

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3vaxPLPUncharacterized protein/1.000
4eb5PLPCysteine desulfurase IscS 2/0.508
1gky5GPGuanylate kinase2.7.4.80.499
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.498
1eyyNAPNADP-dependent fatty aldehyde dehydrogenase1.2.1.40.494
2x06NADL-sulfolactate dehydrogenase/0.491
4eb7PLPCysteine desulfurase IscS 2/0.491
2fdpFRPBeta-secretase 13.4.23.460.490
1xe55FEPlasmepsin-23.4.23.390.489
1xs7MMIBeta-secretase 13.4.23.460.489
2g247IGRenin3.4.23.150.486
3kjiADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.486
2p83MR0Beta-secretase 13.4.23.460.485
3k5fAYHBeta-secretase 13.4.23.460.484
1jedADPSulfate adenylyltransferase/0.483
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.483
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.483
3ixp834Ecdysone receptor/0.483
4d89BXDBeta-secretase 13.4.23.460.483
3wqmB29Diterpene synthase3.1.7.80.482
3ivcFG4Pantothenate synthetase6.3.2.10.481
4loi1YCStimulator of interferon genes protein/0.481
7stdCRPScytalone dehydratase4.2.1.940.481
2wwjY28Lysine-specific demethylase 4A/0.480
2ylrNAPPhenylacetone monooxygenase1.14.13.920.480
3ohh3HHBeta-secretase 13.4.23.460.480
1xe65FPPlasmepsin-23.4.23.390.479
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.479
3lpjZ75Beta-secretase 13.4.23.460.479
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.479
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.479
3kjgADPCO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC/0.478
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.478
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.478
3tjzGNPADP-ribosylation factor 1/0.477
4a83DXCMajor pollen allergen Bet v 1-A/0.477
3fx6BPXCarboxypeptidase A13.4.17.10.476
4ilx1EZCarbonic anhydrase 24.2.1.10.476
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.475
4a81DXCMajor pollen allergen Bet v 1-A/0.475
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.474
4k36SAMAnaerobic sulfatase-maturating enzyme1.8.980.474
1fxsNAPGDP-L-fucose synthase/0.473
1h50FMNPentaerythritol tetranitrate reductase/0.473
1nvtNAPShikimate dehydrogenase (NADP(+))/0.473
2iqgF2IBeta-secretase 13.4.23.460.473
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.473
4lxk1YTBeta-secretase 13.4.23.460.472
5irnADPNucleotide binding oligomerization domain containing 2/0.472
1z44FMNNADPH dehydrogenase/0.471
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.471
2gv8NDPThiol-specific monooxygenase1.14.130.471
2viyVG3Beta-secretase 13.4.23.460.471
2xtnGTPGTPase IMAP family member 2/0.471
4bfvZVVPantothenate kinase2.7.1.330.471
4jnkNAIL-lactate dehydrogenase A chain1.1.1.270.471
2f3fAXFBeta-secretase 13.4.23.460.470
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.470
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.470
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.470
4lutDCSAlanine racemase/0.470
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.470
1nhqFADNADH peroxidase1.11.1.10.469
2hizLIJBeta-secretase 13.4.23.460.469
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.469
3akm11DFatty acid-binding protein, intestinal/0.469
3hgrFMN12-oxophytodienoate reductase 11.3.1.420.469
3imgBZ3Pantothenate synthetase6.3.2.10.469
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.469
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.469
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.469
4qxaGTPRas-related protein Rab-9A/0.469
4to3DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.469
1g1aNADdTDP-glucose 4,6-dehydratase/0.468
1j49NADD-lactate dehydrogenase1.1.1.280.468
2g1n1IGRenin3.4.23.150.468
2i7pACOPantothenate kinase 32.7.1.330.468
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.468
3cib314Beta-secretase 13.4.23.460.468
3ioeA7DPantothenate synthetase6.3.2.10.468
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.468
3q43D66M1 family aminopeptidase3.4.110.468
4araC56Acetylcholinesterase3.1.1.70.468
4h9tHL4Phosphotriesterase/0.468
1kp3ATPArgininosuccinate synthase6.3.4.50.467
1xvaSAMGlycine N-methyltransferase2.1.1.200.467
3ohf3HFBeta-secretase 13.4.23.460.467
4d9eLCSD-cysteine desulfhydrase/0.467
4iah1DXAlr2278 protein/0.467
2ex1C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.466
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.466
3hyoADPPyridoxal kinase/0.466
3jzdNADMaleylacetate reductase/0.466
3qe2FMNNADPH--cytochrome P450 reductase/0.466
4b68NAPL-ornithine N(5)-monooxygenase/0.466
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.466
2vd7PD2Lysine-specific demethylase 4A1.14.110.465
2wzgUPGUncharacterized protein/0.465
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.465
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.465
4exg916Beta-secretase 13.4.23.460.465
4m9aFDAAcyl-CoA dehydrogenase/0.465
4u3jGTPTubulin beta chain/0.465
1s64778Geranylgeranyl transferase type-1 subunit beta2.5.1.590.464
1vhzAPRADP compounds hydrolase NudE3.6.10.464
2dc1NADProbable L-aspartate dehydrogenase/0.464
2f3rG5PGuanylate kinase2.7.4.80.464
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
2g1y5IGRenin3.4.23.150.464
2oapANPType II secretion system protein (GspE-2)/0.464
2rqfJH3Hemolymph juvenile hormone binding protein/0.464
3cic316Beta-secretase 13.4.23.460.464
3cwqADPParA family chromosome partitioning protein/0.464
3sopGDPNeuronal-specific septin-3/0.464
4q71FADBifunctional protein PutA/0.464
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.463
3dm6757Beta-secretase 13.4.23.460.463
3h3qH13Collagen type IV alpha-3-binding protein/0.463
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
3tqcADPPantothenate kinase/0.463
4bb3KKAIsopenicillin N synthase1.21.3.10.463
6stdMS2Scytalone dehydratase4.2.1.940.463
1icsFMN12-oxophytodienoate reductase 11.3.1.420.462
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.462
2b58COADiamine acetyltransferase 1/0.462
2cy0NAPShikimate dehydrogenase (NADP(+))/0.462
2he5NDPAldo-keto reductase family 1 member C211.1.10.462
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.462
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.462
3gwdNAPCyclohexanone monooxygenase/0.462
3phjDHKShikimate dehydrogenase (NADP(+))/0.462
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.462
3qbhQBHBeta-secretase 13.4.23.460.462
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.462
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.462
4du82P0Mevalonate diphosphate decarboxylase/0.462
4mlp2CXCryptochrome-2/0.462
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.462
5kwvANPPantothenate synthetase/0.462
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.461
1beuIPLTryptophan synthase alpha chain/0.461
1ju2FAD(R)-mandelonitrile lyase 24.1.2.100.461
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.461
2ft9CHDFatty acid-binding protein 2, liver/0.461
3enkUPGUDP-glucose 4-epimerase/0.461
3k5dXLIBeta-secretase 13.4.23.460.461
3nsh957Beta-secretase 13.4.23.460.461
3tqxPLP2-amino-3-ketobutyrate coenzyme A ligase/0.461
4dbc3QPAspartate aminotransferase2.6.1.10.461
4i0i957Beta-secretase 13.4.23.460.461
1aa6MGDFormate dehydrogenase H1.1.99.330.460
1xddAAYIntegrin alpha-L/0.460
2ejzSAHDiphthine synthase/0.460
2rlcCHDCholoylglycine hydrolase3.5.1.240.460
2wf2ZY2Beta-secretase 13.4.23.460.460
3cid318Beta-secretase 13.4.23.460.460
3uylTYDProbable NDP-rhamnosyltransferase/0.460
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.460
4gd40WSLysine-specific demethylase 4A1.14.110.460
4k9h1QUBeta-secretase 13.4.23.460.460
1c7oPPGHemolysin/0.459
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.459
1t2cNAIL-lactate dehydrogenase1.1.1.270.459
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2dxdANPNucleoside diphosphate kinase2.7.4.60.459
2ykvIK2Beta-transaminase/0.459
3af1GDPPantothenate kinase2.7.1.330.459
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4dzzADPPlasmid partitioning protein ParF/0.459
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.459
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.459
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.459
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.459
5stdUNNScytalone dehydratase4.2.1.940.459
1m76NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.458
1stdBFSScytalone dehydratase4.2.1.940.458
1vbiNADMalate/L-lactate dehydrogenase family protein/0.458
2bf4FADNADPH--cytochrome P450 reductase/0.458
2briANPUridylate kinase2.7.4.220.458
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.458
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.458
4jayNAPUDP-N-acetylenolpyruvoylglucosamine reductase/0.458
4qak2AMRNA 2',3'-cyclic phosphodiesterase/0.458
1b2lNDCAlcohol dehydrogenase1.1.1.10.457
1ex75GPGuanylate kinase2.7.4.80.457
1icqFMN12-oxophytodienoate reductase 11.3.1.420.457
1typFADTrypanothione reductase1.8.1.120.457
2anb5GPGuanylate kinase2.7.4.80.457
2cv2GSUGlutamate--tRNA ligase6.1.1.170.457
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.457
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.457
2rh9IGPTryptophan synthase alpha chain/0.457
3c35KAIGlutamate receptor ionotropic, kainate 1/0.457
3e6eDCSAlanine racemase/0.457
3h3t16HCollagen type IV alpha-3-binding protein/0.457
3pkdY10Methionine aminopeptidase 2/0.457
4loh1SYStimulator of interferon genes protein/0.457
4p9dTMPDeoxycytidylate deaminase/0.457
3sn6P0GBeta-2 adrenergic receptor/0.457
1lbcCYZGlutamate receptor 2/0.456
1qbqHFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.456
1qbqHFPProtein farnesyltransferase subunit beta2.5.1.580.456
1w4xFADPhenylacetone monooxygenase1.14.13.920.456
1w6hTITPlasmepsin-23.4.23.390.456
1yf8P6CBeta-galactoside-specific lectin 43.2.2.220.456
2a84ATPPantothenate synthetase6.3.2.10.456
2i4qUA4Renin3.4.23.150.456
2iviACWIsopenicillin N synthase1.21.3.10.456
2vkvTDCTetracycline repressor protein class D/0.456
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.456
3g70A5TRenin3.4.23.150.456
3mauPLRPutative sphingosine-1-phosphate lyase/0.456
3vjkM51Dipeptidyl peptidase 4/0.456
4ambDUDPutative glycosyl transferase/0.456
4bfzZVZPantothenate kinase2.7.1.330.456
4fxy0W2Neurolysin, mitochondrial3.4.24.160.456
4i13FOLDihydrofolate reductase1.5.1.30.456
4jqh1MFAlr2278 protein/0.456
4rnwFMNNADPH dehydrogenase 11.6.99.10.456
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.455
1x1aSAMC-20 methyltransferase/0.455
1x28PGUAspartate aminotransferase2.6.1.10.455
2bsxNOSPurine nucleoside phosphorylase/0.455
2wf1ZY1Beta-secretase 13.4.23.460.455
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.455
3t94MTAS-methyl-5'-thioadenosine phosphorylase/0.455
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.455
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.455
4lrlTTPHD domain protein/0.455
4w5kPLPAspartate aminotransferase, mitochondrial/0.455
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.455
5agaANPDNA polymerase theta/0.455
1i59ANPChemotaxis protein CheA2.7.13.30.454
1jd0AZMCarbonic anhydrase 124.2.1.10.454
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.454
2dshSAHDiphthine synthase/0.454
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.454
2ilvC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.454
2v9jATP5'-AMP-activated protein kinase subunit gamma-1/0.454
2vyqFADFerredoxin--NADP reductase1.18.1.20.454
2xy3DUPSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.454
3apwDP0Alpha-1-acid glycoprotein 2/0.454
3d4pNADL-lactate dehydrogenase 11.1.1.270.454
3gqvNAPEnoyl reductase LovC10.454
3i0pNADMalate dehydrogenase, putative/0.454
3imgBZ2Pantothenate synthetase6.3.2.10.454
3opmLUIDipeptidyl peptidase 4/0.454
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.454
4flkY10Methionine aminopeptidase 1/0.454
4g7gVFVLanosterol 14-alpha-demethylase/0.454
4iae1DXAlr2278 protein/0.454
4j75TYMTryptophan--tRNA ligase/0.454
1bk0ACVIsopenicillin N synthase1.21.3.10.453
1odcA8BAcetylcholinesterase3.1.1.70.453
1wuaAP8Actin, alpha skeletal muscle/0.453
2rghFADAlpha-Glycerophosphate Oxidase/0.453
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.453
2x3jATPAcsD/0.453
2y1tDUDSPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS3.6.1.230.453
2z4sADPChromosomal replication initiator protein DnaA/0.453
2zs9ADPPantothenate kinase2.7.1.330.453
3a0tADPSensor histidine kinase/0.453
3vf30GSBeta-secretase 13.4.23.460.453
4e2bFMNDehydrogenase/0.453
4ehyADPTetraacyldisaccharide 4'-kinase/0.453
4nauAGSPhosphopantetheine adenylyltransferase/0.453
4qg1DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.453
1bntAL2Carbonic anhydrase 24.2.1.10.452
1h6bNDPGlucose--fructose oxidoreductase1.1.99.280.452
1rftPXMPyridoxal kinase2.7.1.350.452
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.452
2ejjSAHDiphthine synthase/0.452
2g21L1BRenin3.4.23.150.452
2ikuLIYRenin3.4.23.150.452
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.452
2qtcTDKPyruvate dehydrogenase E1 component1.2.4.10.452
2stdCRPScytalone dehydratase4.2.1.940.452
2x8hFADThioredoxin glutathione reductase/0.452
2y8lADP5'-AMP-activated protein kinase subunit gamma-1/0.452
2yd0BESEndoplasmic reticulum aminopeptidase 13.4.110.452
3p62FMNPentaerythritol tetranitrate reductase/0.452
3qgf46FGenome polyprotein2.7.7.480.452
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3zeiAWHO-acetylserine sulfhydrylase/0.452
4bftZVTPantothenate kinase2.7.1.330.452
4bfxZVXPantothenate kinase2.7.1.330.452
4brgGNPEctonucleoside triphosphate diphosphohydrolase I/0.452
4e2yJHZMethyltransferase/0.452
4mkhAP5Adenylate kinase/0.452
4rww2BALmo2692 protein/0.452
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.451
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.451
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.451
1n2gAPCPantothenate synthetase6.3.2.10.451
1pz0NAPProtein IolS1.1.10.451
1yb5NAPQuinone oxidoreductase1.6.5.50.451
2ahrNAPPyrroline-5-carboxylate reductase/0.451
2b4rAESGlyceraldehyde-3-phosphate dehydrogenase/0.451
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.451
3btsNADGalactose/lactose metabolism regulatory protein GAL80/0.451
3l6jZ90Alr2278 protein/0.451
3m5eJDRCarbonic anhydrase 24.2.1.10.451
3n4bWWZCarbonic anhydrase 24.2.1.10.451
3qeoLLTDeoxycytidine kinase2.7.1.740.451
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.451
4b64FADL-ornithine N(5)-monooxygenase/0.451
4dnaFADProbable glutathione reductase/0.451
4iv6FDAIsovaleryl-CoA dehydrogenase/0.451
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.451
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.450
1gveNAPAflatoxin B1 aldehyde reductase member 310.450
1h36R88Squalene--hopene cyclase4.2.1.1290.450
1ib6NADMalate dehydrogenase/0.450
1if8SBSCarbonic anhydrase 24.2.1.10.450
1txtCAAHMG-CoA synthase/0.450
1xjqADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.450
2dv4SAHDiphthine synthase/0.450
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.450
2jb4A14Isopenicillin N synthase1.21.3.10.450
2qimZEAClass 10 plant pathogenesis-related protein/0.450
2rhgIGPTryptophan synthase alpha chain/0.450
3b1dPLSBetaC-S lyase/0.450
3own3OXRenin3.4.23.150.450
3p67FMNPentaerythritol tetranitrate reductase/0.450
3qt62P0Mevalonate diphosphate decarboxylase/0.450
3s5wNAPL-ornithine N(5)-monooxygenase/0.450
3tr05GPGuanylate kinase/0.450
3v0o4GWHisto-blood group ABO system transferase/0.450
4a802ANMajor pollen allergen Bet v 1-A/0.450
4dpf0LGBeta-secretase 13.4.23.460.450
4k38SAMAnaerobic sulfatase-maturating enzyme1.8.980.450
4n1gCEIObelin/0.450
4tnrDTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.450
4tnzDTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.450
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.450
4xr9NADCalS8/0.450
5ebuFMNLactate oxidase/0.450
5hg0SAMPantothenate synthetase/0.450
1cilETSCarbonic anhydrase 24.2.1.10.449
1icpFMN12-oxophytodienoate reductase 11.3.1.420.449
1k8y13PTryptophan synthase alpha chain/0.449
1kbiFMNCytochrome b2, mitochondrial1.1.2.30.449
1me6IVSPlasmepsin-23.4.23.390.449
1mlzPLPAdenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.449
1r58AO5Methionine aminopeptidase 2/0.449
1sq5ADPPantothenate kinase2.7.1.330.449
1u1f183Uridine phosphorylase2.4.2.30.449
1yw8A75Methionine aminopeptidase 2/0.449
2bjfDXCCholoylglycine hydrolase3.5.1.240.449
2e16SAHDiphthine synthase/0.449
2lfoGCHFatty acid-binding protein, liver/0.449
2wezZYEBeta-secretase 13.4.23.460.449
2y60M8FIsopenicillin N synthase1.21.3.10.449
2zjaACPATP-dependent DNA helicase Hel308/0.449
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3fr5I4AFatty acid-binding protein, adipocyte/0.449
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.449
3pkbY16Methionine aminopeptidase 2/0.449
3q8uADPNucleoside diphosphate kinase/0.449
4bis8HQLysine-specific demethylase 4A1.14.110.449
4dpi0N1Beta-secretase 13.4.23.460.449
4fryNADPutative signal-transduction protein with CBS domains/0.449
4ttaFMCPurine nucleoside phosphorylase DeoD-type/0.449
4xguADPPutative pachytene checkpoint protein 2/0.449
4yxm2BADNA integrity scanning protein DisA/0.449
5iqiGNPBifunctional AAC/APH2.3.10.449
1adfTADAlcohol dehydrogenase E chain1.1.1.10.448
1g4oBSBCarbonic anhydrase 24.2.1.10.448
1h73ANPHomoserine kinase2.7.1.390.448
1i9pIOECarbonic anhydrase 24.2.1.10.448
1qtiGNTAcetylcholinesterase3.1.1.70.448
1rfuADPPyridoxal kinase2.7.1.350.448
1szgFNSCytochrome b2, mitochondrial1.1.2.30.448
1w34FADFerredoxin--NADP reductase1.18.1.20.448
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.448
2c20NADUDP-glucose 4-epimerase/0.448
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.448
2g1r3IGRenin3.4.23.150.448
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.448
2vijC44Beta-secretase 13.4.23.460.448
2wf4ZY4Beta-secretase 13.4.23.460.448
3c8bARG_ARG_GLY_ILE_NH2Botulinum neurotoxin type A3.4.24.690.448
3dr7GPDGDP-perosamine synthase/0.448
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.448
3fvlBHKCarboxypeptidase A13.4.17.10.448
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.448
3h2sNDPPutative NADH-flavin reductase/0.448
3hdyGDUUDP-galactopyranose mutase/0.448
3t84SG6Carbonic anhydrase 24.2.1.10.448
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.448
4hyvPEPPyruvate kinase 12.7.1.400.448
4iawLIZNeutrophil gelatinase-associated lipocalin/0.448
4zwmPLPOrnithine aminotransferase, mitochondrial, putative/0.448
5dw50T1Succinyl-CoA:acetate CoA-transferase/0.448
1a9cGTPGTP cyclohydrolase 13.5.4.160.447
1bil0IURenin3.4.23.150.447
1bn1AL5Carbonic anhydrase 24.2.1.10.447
1h51FMNPentaerythritol tetranitrate reductase/0.447
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.447
1kvkATPMevalonate kinase2.7.1.360.447
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.447
1p9wANPType II secretion system protein E/0.447
1rneC60Renin3.4.23.150.447
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.447
1vftDCSAlanine racemase/0.447
2dvlFADAcyl-CoA dehydrogenase/0.447
2ifaFMNUncharacterized protein/0.447
2il2LIXRenin3.4.23.150.447
2r8fAGSNon-structural protein 23.6.40.447
2tctCTCTetracycline repressor protein class D/0.447
2weoFBWCarbonic anhydrase 24.2.1.10.447
2zvcSAHPrecorrin-3 C17-methyltransferase/0.447
3gkaFMNN-ethylmaleimide reductase/0.447
3gonANPPhosphomevalonate kinase/0.447
3h3r14HCollagen type IV alpha-3-binding protein/0.447
3l77NJPShort-chain alcohol dehydrogenase/0.447
3lpiZ74Beta-secretase 13.4.23.460.447
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.447
3vdqNAD3-hydroxybutyrate dehydrogenase/0.447
3vydVYDRenin3.4.23.150.447
4a862ANMajor pollen allergen Bet v 1-A/0.447
4bcaFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.447
4i8x6P3L-lactate dehydrogenase A chain1.1.1.270.447
4iqgNAPShort-chain dehydrogenase/reductase SDR/0.447
4lxlPD2Lysine-specific demethylase 4B1.14.110.447
4opgFDAConserved Archaeal protein/0.447
4qbgAP5Adenylate kinase/0.447
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.447
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.447
4x5iFOLDihydrofolate reductase1.5.1.30.447
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.447
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.447
5c7hNDPPutative oxidoreductase/0.447
1cq6PY4Aspartate aminotransferase2.6.1.10.446
1dliUDXUDP-glucose 6-dehydrogenase/0.446
1g54FFBCarbonic anhydrase 24.2.1.10.446
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.446
1kfbIGPTryptophan synthase alpha chain/0.446
1mbbEEBUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.446
1mjaCOAHistone acetyltransferase ESA1/0.446
1n2hPAJPantothenate synthetase6.3.2.10.446
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.446
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.446
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.446
1w5tADPORC1-type DNA replication protein 2/0.446
2d3aADPGlutamine synthetase root isozyme 36.3.1.20.446
2g8aUMPThymidylate synthase/0.446
2jl1NAPTriphenylmethane reductase/0.446
2pb4SAHDiphthine synthase/0.446
2xpwOTCTetracycline repressor protein class D/0.446
3g0dXIHDipeptidyl peptidase 4/0.446
3m1vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.446
3m1vCOMMethyl-coenzyme M reductase I subunit beta2.8.4.10.446
3m2yBE0Carbonic anhydrase 24.2.1.10.446
3m34TPPTransketolase/0.446
3nd6ATPPhosphopantetheine adenylyltransferase/0.446
3ppr4CSGlycine betaine/carnitine/choline-binding protein OpuCC/0.446
3rbaCODPhosphopantetheine adenylyltransferase/0.446
4a6rTA8Probable aminotransferase/0.446
4jtqNAPAldo-keto reductase family 1 member C2/0.446
4m2bUPGUDP-glucose pyrophosphorylase/0.446
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.446
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.446
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
5a8aADPRiboflavin biosynthesis protein RibF2.7.1.260.446
5dw60T1Succinyl-CoA:acetate CoA-transferase/0.446
1ahgTYR_PLPAspartate aminotransferase2.6.1.10.445
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.445
1esvLARActin, alpha skeletal muscle/0.445
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.445
1mj9COAHistone acetyltransferase ESA1/0.445
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.445
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.445
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1t7o152Carnitine O-acetyltransferase2.3.1.70.445
1u65CP0Acetylcholinesterase3.1.1.70.445
1zsbAZMCarbonic anhydrase 24.2.1.10.445
2a94AP0L-lactate dehydrogenase1.1.1.270.445
2an9GDPGuanylate kinase2.7.4.80.445
2givACOHistone acetyltransferase KAT8/0.445
2pncCLUPrimary amine oxidase, liver isozyme/0.445
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.445
2yj5ATPCopper-transporting ATPase/0.445
3fhxPXLPyridoxal kinase2.7.1.350.445
3giyFMN(S)-mandelate dehydrogenase1.1.99.310.445
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.445
3ivxFG6Pantothenate synthetase6.3.2.10.445
3lpkZ76Beta-secretase 13.4.23.460.445
3muoZPRProlyl endopeptidase/0.445
3ogxH1SPeptidoglycan recognition protein 1/0.445
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.445
4b65FADL-ornithine N(5)-monooxygenase/0.445
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.445
4djaFAD(6-4) photolyase/0.445
4egbNADdTDP-glucose 4,6-dehydratase/0.445
4i1iNADMalate dehydrogenase/0.445
4oplFDAConserved Archaeal protein/0.445
4rjeFNRLactate oxidase/0.445
5c48URMHisto-blood group ABO system transferase/0.445
5dhaGNPGTP-binding nuclear protein Ran/0.445
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.445
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.444
1cozCTPGlycerol-3-phosphate cytidylyltransferase2.7.7.390.444
1kfcIPLTryptophan synthase alpha chain/0.444
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.444
1nhkCMPNucleoside diphosphate kinase2.7.4.60.444
1p0hACOMycothiol acetyltransferase2.3.1.1890.444
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.444
1q45FMN12-oxophytodienoate reductase 31.3.1.420.444
1szfFMNCytochrome b2, mitochondrial1.1.2.30.444
1wvgCXYCDP-glucose 4,6-dehydratase4.2.1.450.444
1xnjADPBifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 12.7.1.250.444
2g1o2IGRenin3.4.23.150.444
2g94ZPQBeta-secretase 13.4.23.460.444
2o3uNGDADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.444
2uyyNA7Putative oxidoreductase GLYR110.444
2vj6VG5Beta-secretase 13.4.23.460.444
2w6cBM4Acetylcholinesterase3.1.1.70.444
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.444
3dv5BAVBeta-secretase 13.4.23.460.444
3hdyFDAUDP-galactopyranose mutase/0.444
3hl4CDCCholine-phosphate cytidylyltransferase A/0.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3udj092Beta-secretase 13.4.23.460.444
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.444
4lu3AZMCarbonic anhydrase 144.2.1.10.444
4ycpFMNtRNA-dihydrouridine(16) synthase/0.444
1fy7COAHistone acetyltransferase ESA1/0.443
1gpdNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.443
1h60STRPentaerythritol tetranitrate reductase/0.443
1il0NADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.443
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.443
1uayADNOxidoreductase/0.443
2c6c24IGlutamate carboxypeptidase 23.4.17.210.443
2cekN8TAcetylcholinesterase3.1.1.70.443
2ffqGSPRas-related protein Rab-6B/0.443
2gesCOKPantothenate kinase2.7.1.330.443
2nliFMNLactate oxidase/0.443
2pb6SAHDiphthine synthase/0.443
2pgtGPRGlutathione S-transferase P2.5.1.180.443
2q2vNADBeta-D-hydroxybutyrate dehydrogenase/0.443
2q4bNAPUncharacterized protein At5g02240/0.443
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.443
2uuvFADAlkyldihydroxyacetonephosphate synthase2.5.1.260.443
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.443
2v7qATPATP synthase subunit alpha, mitochondrial/0.443
2v7qATPATP synthase subunit beta, mitochondrial3.6.3.140.443
2yimMC4Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.443
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.443
2zsaADPPantothenate kinase2.7.1.330.443
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.443
3kigDA4Carbonic anhydrase 24.2.1.10.443
3m98E02Carbonic anhydrase 24.2.1.10.443
3ml2SU0Carbonic anhydrase 24.2.1.10.443
3nzpPLPArginine decarboxylase/0.443
3rsv3RSBeta-secretase 13.4.23.460.443
4a87NARMajor pollen allergen Bet v 1-A/0.443
4bfuZVUPantothenate kinase2.7.1.330.443
4cdmFO1Deoxyribodipyrimidine photolyase/0.443
4d6qPD2Lysine-specific demethylase 4D1.14.110.443
4ddhMS0Pantothenate synthetase6.3.2.10.443
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.443
4fvqATPTyrosine-protein kinase JAK2/0.443
4i0h1BLBeta-secretase 13.4.23.460.443
4lzwTHMUridine phosphorylase/0.443
4relKMPGlycosyltransferase/0.443
4yaw2AMNADPH--cytochrome P450 reductase/0.443
5bv3M7Gm7GpppX diphosphatase3.6.1.590.443
6ctsCICCitrate synthase, mitochondrial2.3.3.10.443
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1kh3ANPArgininosuccinate synthase/0.442
1n2eAPCPantothenate synthetase6.3.2.10.442
1t2aNDPGDP-mannose 4,6 dehydratase4.2.1.470.442
1vgqCAOFormyl-CoA:oxalate CoA-transferase/0.442
1w6rGNTAcetylcholinesterase3.1.1.70.442
1y9dTPPPyruvate oxidase1.2.3.30.442
2e17SAHDiphthine synthase/0.442
2eixFADNADH-cytochrome b5 reductase/0.442
2g1s4IGRenin3.4.23.150.442
2getCOKPantothenate kinase2.7.1.330.442
2i7nACOPantothenate kinase 12.7.1.330.442
2ix5FADAcyl-coenzyme A oxidase 4, peroxisomal1.3.3.60.442
2rc4ACOHistone acetyltransferase KAT6A/0.442
2vnnCM7Beta-secretase 13.4.23.460.442
2wtkANPSTE20-related kinase adapter protein alpha/0.442
2xlrFADPutative flavin-containing monooxygenase/0.442
2yxuATPPyridoxal kinase2.7.1.350.442
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.442
3bk2U5PRibonuclease J/0.442
3h86AP5Adenylate kinase/0.442
3ie3N11Glutathione S-transferase P2.5.1.180.442
3in6FMNUncharacterized protein/0.442
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.442
3m2uCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.442
3o76GTBGlutathione S-transferase P 12.5.1.180.442
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.442
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.442
3zoiM2WIsopenicillin N synthase1.21.3.10.442
4df2FMNNADPH dehydrogenase/0.442
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.442
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.442
4lol1YEStimulator of interferon genes protein/0.442
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
5a1tNAIL-lactate dehydrogenase/0.442
1ay0TPPTransketolase 12.2.1.10.441
1dfoPLGSerine hydroxymethyltransferase2.1.2.10.441
1dorFMNDihydroorotate dehydrogenase A (fumarate)1.3.98.10.441
1g9dBABBotulinum neurotoxin type B3.4.24.690.441
1gaxVAAValine--tRNA ligase6.1.1.90.441
1if7SBRCarbonic anhydrase 24.2.1.10.441
1ja0FADNADPH--cytochrome P450 reductase/0.441
1l8aTDPPyruvate dehydrogenase E1 component1.2.4.10.441
1o9bNAIQuinate/shikimate dehydrogenase/0.441
1u1cBAUUridine phosphorylase2.4.2.30.441
2e8qSAHDiphthine synthase/0.441
2eh5SAHDiphthine synthase/0.441
2el0SAHDiphthine synthase/0.441
2g8yNADHydroxycarboxylate dehydrogenase B/0.441
2gd6ACOProbable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase )/0.441
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.441
2v59LZKBiotin carboxylase6.3.4.140.441
2x7hPFNProstaglandin reductase 310.441
2ylzFADPhenylacetone monooxygenase1.14.13.920.441
3akn11DFatty acid-binding protein, intestinal/0.441
3b2sB2STrichothecene 3-O-acetyltransferase/0.441
3b70NAPEnoyl reductase LovC10.441
3dt2GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.441
3fr4F8AFatty acid-binding protein, adipocyte/0.441
3ieuGDPGTPase Era/0.441
3kb1ADPIron-sulfur cluster carrier protein/0.441
3lb8FADPutidaredoxin reductase1.18.1.50.441
3p82FMNPentaerythritol tetranitrate reductase/0.441
3r2fPB0Beta-secretase 13.4.23.460.441
3skgPB8Beta-secretase 13.4.23.460.441
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.441
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.441
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.441
4dldTZGGlutamate receptor ionotropic, kainate 1/0.441
4dptAGSMevalonate diphosphate decarboxylase/0.441
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.441
4l1xNAPAldo-keto reductase family 1 member C2/0.441
4la1FADThioredoxin glutathione reductase/0.441
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.441
4q73FADBifunctional protein PutA/0.441
4u0zAPCAdenosine monophosphate-protein transferase FICD2.7.7.n10.441
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.441
4x28FDAAcyl-CoA dehydrogenase FadE26/0.441
4x28FDAAcyl-CoA dehydrogenase FadE27/0.441
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.441
4zgsNADPutative D-lactate dehydrogenase/0.441
1dgfNDPCatalase1.11.1.60.440
1g6oADPCag alpha/0.440
1joaFADNADH peroxidase1.11.1.10.440
1kqcFMNOxygen-insensitive NAD(P)H nitroreductase/0.440
1o97FADElectron transfer flavoprotein subunit alpha/0.440
1pqc444Oxysterols receptor LXR-beta/0.440
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.440
1udaUFGUDP-glucose 4-epimerase5.1.3.20.440
1vkgCRIHistone deacetylase 83.5.1.980.440
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.440
2c29NAPDihydroflavonol 4-reductase/0.440
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.440
2dg4RAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.440
2dxiATPGlutamate--tRNA ligase6.1.1.170.440
2ek7SAHDiphthine synthase/0.440
2futH1SHeparin and heparin-sulfate lyase/0.440
2vn1FK5Peptidylprolyl isomerase/0.440
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.440
3mzhCMPCRP-like cAMP-activated global transcriptional regulator/0.440
3nl6TPSUncharacterized protein/0.440
3phiNDPShikimate dehydrogenase (NADP(+))/0.440
3qe0GDPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.440
3qsaTA7Anthranilate phosphoribosyltransferase/0.440
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.440
4de3DN8Beta-lactamase/0.440
4dieC5PCytidylate kinase/0.440
4eudCOASuccinyl-CoA:acetate CoA-transferase/0.440
4fkzUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.440
4tmbFMNOld yellow enzyme/0.440
4tnyDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.440
4xbjIN5Alanine racemase, biosynthetic/0.440
4xsvCTPEthanolamine-phosphate cytidylyltransferase2.7.7.140.440