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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3o76GTBGlutathione S-transferase P 12.5.1.18

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3o76GTBGlutathione S-transferase P 12.5.1.181.000
1aqv0HGGlutathione S-transferase P2.5.1.180.626
13gsSASGlutathione S-transferase P2.5.1.180.620
2pgtGPRGlutathione S-transferase P2.5.1.180.618
2oadGTBGlutathione S-transferase P 12.5.1.180.614
17gsGTXGlutathione S-transferase P2.5.1.180.613
2oa7GTXGlutathione S-transferase P 12.5.1.180.593
3gusN11Glutathione S-transferase P2.5.1.180.592
1aqxGTDGlutathione S-transferase P2.5.1.180.591
2a2sGSNGlutathione S-transferase P2.5.1.180.588
3csjCBLGlutathione S-transferase P2.5.1.180.584
9gssGTXGlutathione S-transferase P2.5.1.180.584
2glrGTXGlutathione S-transferase P 12.5.1.180.583
2oacGTBGlutathione S-transferase P 12.5.1.180.574
2j9hGTXGlutathione S-transferase P2.5.1.180.572
20gsCBDGlutathione S-transferase P2.5.1.180.568
3n9jEAAGlutathione S-transferase P2.5.1.180.561
3ie3N11Glutathione S-transferase P2.5.1.180.557
1pgtGTXGlutathione S-transferase P2.5.1.180.549
3pgtGBXGlutathione S-transferase P2.5.1.180.532
1tu8GTXGlutathione S-transferase 22.5.1.180.531
2uxoTACHTH-type transcriptional regulator TtgR/0.510
4iah1DXAlr2278 protein/0.506
2zi63D1Deoxycytidine kinase2.7.1.740.502
1obnASVIsopenicillin N synthase1.21.3.10.499
3qeoLLTDeoxycytidine kinase2.7.1.740.498
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.497
1yw8A75Methionine aminopeptidase 2/0.496
4k88HFGBifunctional glutamate/proline--tRNA ligase6.1.1.150.495
2j3qTFLAcetylcholinesterase3.1.1.70.494
3f90FMNFlavodoxin/0.494
4jqh1MFAlr2278 protein/0.492
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.491
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.491
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.490
3rtnRTNBeta-secretase 13.4.23.460.490
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.489
1gssLEEGlutathione S-transferase P2.5.1.180.488
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.488
2dxiATPGlutamate--tRNA ligase6.1.1.170.488
1ja0FADNADPH--cytochrome P450 reductase/0.487
1qoqIGPTryptophan synthase alpha chain/0.487
3v2uATPProtein GAL3/0.487
4bb3KKAIsopenicillin N synthase1.21.3.10.487
2gevCOKPantothenate kinase2.7.1.330.486
2jf0HBPAcetylcholinesterase3.1.1.70.485
2zsaADPPantothenate kinase2.7.1.330.485
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.484
2nnqT4BFatty acid-binding protein, adipocyte/0.483
4eqsCOACoenzyme A disulfide reductase/0.483
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.482
3ufl508Beta-secretase 13.4.23.460.482
4bfuZVUPantothenate kinase2.7.1.330.482
4kniE1ECarbonic anhydrase 24.2.1.10.482
2ea4F79Methionine aminopeptidase 2/0.481
2rqfJH3Hemolymph juvenile hormone binding protein/0.481
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.481
4gt8ADPSensor protein VraS2.7.13.30.481
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.480
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.480
3rviRVIBeta-secretase 13.4.23.460.480
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.480
4bfvZVVPantothenate kinase2.7.1.330.480
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.479
2a4xBLMMitomycin-binding protein/0.479
3aezGDPPantothenate kinase2.7.1.330.479
3s5wFADL-ornithine N(5)-monooxygenase/0.479
4b6uM7GEukaryotic translation initiation factor 4E type 3/0.479
1vbiNADMalate/L-lactate dehydrogenase family protein/0.478
2vd0D27Hematopoietic prostaglandin D synthase/0.478
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
3vkjFNRIsopentenyl-diphosphate delta-isomerase/0.478
3zkyWT4Isopenicillin N synthase1.21.3.10.478
4bftZVTPantothenate kinase2.7.1.330.478
1r5hAO2Methionine aminopeptidase 2/0.477
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.477
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.477
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.476
4a87NARMajor pollen allergen Bet v 1-A/0.476
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.476
2gesCOKPantothenate kinase2.7.1.330.475
3br3ETHTH-type transcriptional regulator QacR/0.475
3h3r14HCollagen type IV alpha-3-binding protein/0.475
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.475
4bfxZVXPantothenate kinase2.7.1.330.475
4bfzZVZPantothenate kinase2.7.1.330.475
4iae1DXAlr2278 protein/0.475
1yqzCOACoenzyme A disulfide reductase/0.474
2bf4FADNADPH--cytochrome P450 reductase/0.474
2ejzSAHDiphthine synthase/0.474
2zevB71Geranylgeranyl pyrophosphate synthase/0.474
3dgqEAAGlutathione S-transferase P2.5.1.180.474
1c7oPPGHemolysin/0.473
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.473
2po3T4K4-dehydrase/0.473
4acuQN7Beta-secretase 13.4.23.460.473
1towCRZFatty acid-binding protein, adipocyte/0.472
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.472
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
2vi5Y196,7-dimethyl-8-ribityllumazine synthase2.5.1.780.472
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.472
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.472
4nv1TYDFormyl transferase/0.472
3l6jZ90Alr2278 protein/0.471
4rh10TTSpore photoproduct lyase/0.471
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.470
1if6FBUCarbonic anhydrase 24.2.1.10.470
1l2tATPUncharacterized ABC transporter ATP-binding protein MJ0796/0.470
3b6pTMPThree-prime repair exonuclease 13.1.11.20.470
3udj092Beta-secretase 13.4.23.460.470
1ry0PG2Aldo-keto reductase family 1 member C3/0.469
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.469
2cmfF11Acetylcholinesterase3.1.1.70.469
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.469
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.469
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.469
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.469
4c717RD3-oxoacyl-ACP synthase/0.469
4eepFMNPhototropin-22.7.11.10.469
4yao2AMNADPH--cytochrome P450 reductase/0.469
1uhhCZPAequorin-2/0.468
2clmF6FTryptophan synthase alpha chain/0.468
2xupTZ5Acetylcholinesterase3.1.1.70.468
2xviFADPutative flavin-containing monooxygenase/0.468
3aosJH2Hemolymph juvenile hormone binding protein/0.468
3e6eDCSAlanine racemase/0.468
4c6zTLE3-oxoacyl-ACP synthase/0.468
1qzyTDEMethionine aminopeptidase 2/0.467
2bu9HFVIsopenicillin N synthase1.21.3.10.467
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.467
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
4b0532DBeta-secretase 13.4.23.460.467
4j7hTRHPCZA361.3/0.467
4n16CHDCarbonic anhydrase 24.2.1.10.467
1jf0CZHObelin/0.466
1q84TZ4Acetylcholinesterase3.1.1.70.466
2x06NADL-sulfolactate dehydrogenase/0.466
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.466
3igpDT7Carbonic anhydrase 24.2.1.10.466
3po6DT9Carbonic anhydrase 24.2.1.10.466
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.466
4eqwCOACoenzyme A disulfide reductase/0.466
5stdUNNScytalone dehydratase4.2.1.940.466
1a80NDP2,5-diketo-D-gluconic acid reductase A1.1.1.3460.465
1d3dBZTProthrombin3.4.21.50.465
1r5gAO1Methionine aminopeptidase 2/0.465
1x1cSAHC-20 methyltransferase/0.465
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.465
2zs8ADPPantothenate kinase2.7.1.330.465
3bl7DD1m7GpppX diphosphatase3.6.1.590.465
3ghh2NFCD38 molecule/0.465
3n19FNRXenobiotic reductase/0.465
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.465
4fx9COACoenzyme A disulfide reductase1.8.1.140.465
1bk0ACVIsopenicillin N synthase1.21.3.10.464
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.464
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.464
1pr4MTPPurine nucleoside phosphorylase DeoD-type/0.464
1qiqACCIsopenicillin N synthase1.21.3.10.464
1xddAAYIntegrin alpha-L/0.464
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.464
3h3t16HCollagen type IV alpha-3-binding protein/0.464
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.464
4fizCUE17beta-hydroxysteroid dehydrogenase/0.464
4m9aFDAAcyl-CoA dehydrogenase/0.464
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
1xe65FPPlasmepsin-23.4.23.390.463
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.463
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
2whqHI6Acetylcholinesterase3.1.1.70.463
3pm1ETHTH-type transcriptional regulator QacR/0.463
3sbhE65Carbonic anhydrase 24.2.1.10.463
1b2lNDCAlcohol dehydrogenase1.1.1.10.462
1qv0CZHObelin/0.462
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.462
3c1oNAPEugenol synthase/0.462
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3juoAJDPhenazine biosynthesis protein A/B/0.462
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3l5lFMNXenobiotic reductase/0.462
3rsv3RSBeta-secretase 13.4.23.460.462
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.462
4frkDWDBeta-secretase 13.4.23.460.462
4n1gCEIObelin/0.462
4n3r2GUTankyrase-12.4.2.300.462
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.462
1zsbAZMCarbonic anhydrase 24.2.1.10.461
2cekN8TAcetylcholinesterase3.1.1.70.461
2e94364Geranylgeranyl pyrophosphate synthase/0.461
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3uyk0CXProbable NDP-rhamnosyltransferase/0.461
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.461
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.461
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.461
1pqc444Oxysterols receptor LXR-beta/0.460
2gpjFADSiderophore-interacting protein/0.460
2wzySQXSoluble acetylcholine receptor/0.460
2x7tWZBCarbonic anhydrase 24.2.1.10.460
2xuiTZ5Acetylcholinesterase3.1.1.70.460
2xvfFADPutative flavin-containing monooxygenase/0.460
3c3xNAPEugenol synthase 11.1.1.3180.460
3e8xNAPBH1520 protein/0.460
3n3aFMNProtein NrdI/0.460
4epq0RRPoly(ADP-ribose) glycohydrolase/0.460
4wx2F6FTryptophan synthase alpha chain/0.460
4wx2F6FTryptophan synthase beta chain4.2.1.200.460
5efwFMNNPH1-1/0.460
1oklMNSCarbonic anhydrase 24.2.1.10.459
1ry8RUTAldo-keto reductase family 1 member C3/0.459
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.459
1u65CP0Acetylcholinesterase3.1.1.70.459
1vfsDCSAlanine racemase/0.459
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1yhjR6CPyridoxal kinase2.7.1.350.459
2w6pOA4Biotin carboxylase6.3.4.140.459
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3fr5I4AFatty acid-binding protein, adipocyte/0.459
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.459
3hl0NADMaleylacetate reductase/0.459
4azy7F3Beta-secretase 13.4.23.460.459
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.459
4bfwZVWPantothenate kinase2.7.1.330.459
4bquCLRJapanin/0.459
4lutDCSAlanine racemase/0.459
5fd8A5APutative carboxypeptidase yocD/0.459
6stdMS2Scytalone dehydratase4.2.1.940.459
1mtcGPRGlutathione S-transferase Mu 12.5.1.180.458
1n77ATPGlutamate--tRNA ligase6.1.1.170.458
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.458
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.458
3b78NADExotoxin A2.4.2.360.458
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.458
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.458
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
4ryvZEAProtein LlR18A/0.458
4w5kPLPAspartate aminotransferase, mitochondrial/0.458
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.457
1xs7MMIBeta-secretase 13.4.23.460.457
2ea2F77Methionine aminopeptidase 2/0.457
2eu3FF3Carbonic anhydrase 24.2.1.10.457
3c35KAIGlutamate receptor ionotropic, kainate 1/0.457
3f6sFMNFlavodoxin/0.457
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
3vf60H6Glucokinase2.7.1.20.457
4a86H35Major pollen allergen Bet v 1-A/0.457
4id9NADPutative UDP-glucose 4-epimerase/0.457
4jtrIBPAldo-keto reductase family 1 member C2/0.457
4nv14TGFormyl transferase/0.457
4xoqF42Coenzyme F420:L-glutamate ligase/0.457
4u163C0Muscarinic acetylcholine receptor M3/0.457
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1p33MTXPteridine reductase 11.5.1.330.456
1q23FUAChloramphenicol acetyltransferase2.3.1.280.456
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.456
2g226IGRenin3.4.23.150.456
2geuCOKPantothenate kinase2.7.1.330.456
2uuk897Prothrombin3.4.21.50.456
3caqNDP3-oxo-5-beta-steroid 4-dehydrogenase/0.456
3m2yBE0Carbonic anhydrase 24.2.1.10.456
3m67E36Carbonic anhydrase 24.2.1.10.456
4bfsZVSPantothenate kinase2.7.1.330.456
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.456
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.456
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.456
6gsuGPSGlutathione S-transferase Mu 12.5.1.180.456
3vw7VPXProteinase-activated receptor 1/0.456
1eveE20Acetylcholinesterase3.1.1.70.455
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.455
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.455
2ixkTDOdTDP-4-dehydrorhamnose 3,5-epimerase5.1.3.130.455
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.455
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.455
2oazI96Methionine aminopeptidase 2/0.455
2onmADPAldehyde dehydrogenase, mitochondrial1.2.1.30.455
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.455
3h3qH13Collagen type IV alpha-3-binding protein/0.455
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.455
3v0p4GWHisto-blood group ABO system transferase/0.455
3zhtTD9Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.455
4b1c1B1Beta-secretase 13.4.23.460.455
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.455
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.455
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4lnbED5CaaX farnesyltransferase beta subunit Ram1/0.455
4uy6SAHHistidine N-alpha-methyltransferase/0.455
7stdCRPScytalone dehydratase4.2.1.940.455
1i90INMCarbonic anhydrase 24.2.1.10.454
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.454
1r58AO5Methionine aminopeptidase 2/0.454
1touB1VFatty acid-binding protein, adipocyte/0.454
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.454
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1zgbA1EAcetylcholinesterase3.1.1.70.454
3dzl3OCPhenazine biosynthesis protein A/B/0.454
3ewkFADSensory box histidine kinase/response regulator/0.454
3f3y4OABile salt sulfotransferase2.8.2.140.454
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.454
4b68NAPL-ornithine N(5)-monooxygenase/0.454
4jyzATPGlutamine--tRNA ligase6.1.1.180.454
4uugPXGBranched-chain amino acid aminotransferase, putative/0.454
5a4wQCTGlutathione S-transferase F22.5.1.180.454
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.453
1gj4132Prothrombin3.4.21.50.453
1gj5130Prothrombin3.4.21.50.453
2v7qADPATP synthase subunit beta, mitochondrial3.6.3.140.453
2vbdV10Isopenicillin N synthase1.21.3.10.453
3b4fTUOCarbonic anhydrase 24.2.1.10.453
3gncQQQGlutaryl-CoA dehydrogenase/0.453
3ojgHL4Phosphotriesterase/0.453
3w6hAZMCarbonic anhydrase 14.2.1.10.453
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.453
3zw9NADPeroxisomal bifunctional enzyme1.1.1.350.453
4bekXK0Beta-secretase 13.4.23.460.453
4cdmFO1Deoxyribodipyrimidine photolyase/0.453
4jqaID8Aldo-keto reductase family 1 member C2/0.453
4m0f1YKAcetylcholinesterase3.1.1.70.453
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.453
1fmlRTLRetinol dehydratase/0.452
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.452
1odcA8BAcetylcholinesterase3.1.1.70.452
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
1s1rNAPAldo-keto reductase family 1 member C3/0.452
1u1f183Uridine phosphorylase2.4.2.30.452
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.452
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.452
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3gw9VNILanosterol 14-alpha-demethylase/0.452
3ivcFG4Pantothenate synthetase6.3.2.10.452
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.452
3nu03TUDihydrofolate reductase1.5.1.30.452
3slkNDPPolyketide synthase extender module 2/0.452
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.452
4h9tHL4Phosphotriesterase/0.452
4l96LRGPeroxisome proliferator-activated receptor gamma/0.452
4tlxFDAKtzI/0.452
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.451
1if8SBSCarbonic anhydrase 24.2.1.10.451
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
1n2iPAJPantothenate synthetase6.3.2.10.451
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.451
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.451
1x8lOXRRetinol dehydratase/0.451
1yunATPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.451
2g1a5HGClass B acid phosphatase3.1.3.20.451
2i4qUA4Renin3.4.23.150.451
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.451
3bi6396Wee1-like protein kinase2.7.10.20.451
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.451
3n5yXFLNitric oxide synthase, brain1.14.13.390.451
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.451
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.451
4f1yCNIGlutamate receptor 3/0.451
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.451
4nv10FXFormyl transferase/0.451
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA23.6.30.451
4zirANPEnergy-coupling factor transporter ATP-binding protein EcfA1/0.451
5d5aCAUBeta-2 adrenergic receptor/0.451
4u140HKMuscarinic acetylcholine receptor M3/0.451
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1x1bSAHC-20 methyltransferase/0.450
1ypgUIRProthrombin3.4.21.50.450
2b8jADNClass B acid phosphatase3.1.3.20.450
2vrjNCWBeta-glucosidase A3.2.1.210.450
3b9lAZZSerum albumin/0.450
3oimVZ5Carbonic anhydrase 24.2.1.10.450
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
4d1oH4BNitric oxide synthase, endothelial1.14.13.390.450
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.450
4ruoBIVVitamin D3 receptor A/0.450
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.450
5dp2NAPCurF/0.450
1acjTHAAcetylcholinesterase3.1.1.70.449
1dghNDPCatalase1.11.1.60.449
1gpeFADGlucose oxidase1.1.3.40.449
1gtrATPGlutamine--tRNA ligase6.1.1.180.449
1i8zINLCarbonic anhydrase 24.2.1.10.449
1mxfMTXPutative pteridine reductase 2/0.449
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.449
1rzuADPGlycogen synthase 12.4.1.210.449
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.449
1w29TS06,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2bf4FMNNADPH--cytochrome P450 reductase/0.449
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.449
2oegUPGUDP-glucose pyrophosphorylase/0.449
2xlpNAPPutative flavin-containing monooxygenase/0.449
2xuoTZ4Acetylcholinesterase3.1.1.70.449
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
2zsdCOAPantothenate kinase2.7.1.330.449
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.449
3lnsNAPNAD(P)-dependent benzaldehyde dehydrogenase1.2.1.280.449
3qen5BTDeoxycytidine kinase2.7.1.740.449
3tifADPUncharacterized ABC transporter ATP-binding protein MJ0796/0.449
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.449
4c49HCYCorticosteroid-binding globulin/0.449
4kbyC2EStimulator of interferon genes protein/0.449
5c1gGDUHisto-blood group ABO system transferase/0.449
1dx6GNTAcetylcholinesterase3.1.1.70.448
1fmjRTLRetinol dehydratase/0.448
1h22E10Acetylcholinesterase3.1.1.70.448
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.448
1rftPXMPyridoxal kinase2.7.1.350.448
1rpwDIDHTH-type transcriptional regulator QacR/0.448
2a3bCFFEndochitinase B13.2.1.140.448
2po7CHDFerrochelatase, mitochondrial4.99.1.10.448
2v59LZKBiotin carboxylase6.3.4.140.448
2wehFB1Carbonic anhydrase 24.2.1.10.448
2xytTC9Soluble acetylcholine receptor/0.448
3hk1B64Fatty acid-binding protein, adipocyte/0.448
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.448
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.448
4eqrCOACoenzyme A disulfide reductase/0.448
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.448
4h1e10JBeta-secretase 13.4.23.460.448
4nqgCZHMitrocomin/0.448
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
1esmCOAPantothenate kinase2.7.1.330.447
1h60STRPentaerythritol tetranitrate reductase/0.447
1j9zFADNADPH--cytochrome P450 reductase/0.447
1o9bNAIQuinate/shikimate dehydrogenase/0.447
1qtiGNTAcetylcholinesterase3.1.1.70.447
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.447
1uzwCDHIsopenicillin N synthase1.21.3.10.447
1xh7R96cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2bxqIMNSerum albumin/0.447
2d06ESTSulfotransferase 1A12.8.2.10.447
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.447
2iejS48Protein farnesyltransferase subunit beta2.5.1.580.447
2rehFADNitroalkane oxidase1.7.3.10.447
2x7hPFNProstaglandin reductase 310.447
3c1tMYCDihydroflavonol 4-reductase1.1.1.2190.447
3gwfFADCyclohexanone monooxygenase/0.447
3ojxFMNNADPH--cytochrome P450 reductase/0.447
3stdMQ0Scytalone dehydratase4.2.1.940.447
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.447
4ge90L0Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.447
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
4jiq1L5GTN Reductase/0.447
4jlm1NNDeoxycytidine kinase2.7.1.740.447
4jt81NRNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.447
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.447
4xwtU5PRibonuclease J/0.447
5fltVJJCarbonic anhydrase 24.2.1.10.447
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.446
1cq6PY4Aspartate aminotransferase2.6.1.10.446
1k7fIAVTryptophan synthase alpha chain/0.446
1w76GNTAcetylcholinesterase3.1.1.70.446
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2g1o2IGRenin3.4.23.150.446
2gv8NDPThiol-specific monooxygenase1.14.130.446
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.446
2vn1FK5Peptidylprolyl isomerase/0.446
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.446
3b8hNADExotoxin A2.4.2.360.446
3bk2U5PRibonuclease J/0.446
3dz4C8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.446
3h0wN8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.446
3kigDA4Carbonic anhydrase 24.2.1.10.446
3p0fBAUUridine phosphorylase 22.4.2.30.446
4acxS8ZBeta-secretase 13.4.23.460.446
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.446
4krs1SXTankyrase-12.4.2.300.446
4lxa1YSBeta-secretase 13.4.23.460.446
4rphGDUUDP-galactopyranose mutase5.4.99.90.446
4zqcF6FTryptophan synthase alpha chain/0.446
5ah5LSSLeucine--tRNA ligase/0.446
1bnwTPDCarbonic anhydrase 24.2.1.10.445
1el4CTZObelin/0.445
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.445
1oc1ASVIsopenicillin N synthase1.21.3.10.445
1toiHCIAspartate aminotransferase2.6.1.10.445
1w06W05Isopenicillin N synthase1.21.3.10.445
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.445
2pl0STITyrosine-protein kinase Lck2.7.10.20.445
2y05RALProstaglandin reductase 1/0.445
2zs9ADPPantothenate kinase2.7.1.330.445
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.445
3dr7GPDGDP-perosamine synthase/0.445
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.445
3ix4TX1Transcriptional activator protein LasR/0.445
3junAJDPhenazine biosynthesis protein A/B/0.445
3k1wBFXRenin3.4.23.150.445
3lxeTORCarbonic anhydrase 14.2.1.10.445
3occDIHPurine nucleoside phosphorylase DeoD-type/0.445
3pkaY02Methionine aminopeptidase 2/0.445
3qe2FMNNADPH--cytochrome P450 reductase/0.445
3sf6FDAGlutaryl-CoA dehydrogenase/0.445
3ug8IMNAldo-keto reductase family 1 member C3/0.445
3wqmB29Diterpene synthase3.1.7.80.445
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.445
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
4boeCLRJapanin/0.445
4c73TLH3-oxoacyl-ACP synthase/0.445
4hmvWUBPhenazine biosynthesis protein PhzG1.40.445
4tkg09LTankyrase-22.4.2.300.445
5bp9SAHPutative methyltransferase protein/0.445
5dozNDPJamJ/0.445
1diaL24C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.444
1g63FMNEpidermin decarboxylase4.1.10.444
1hb3SCVIsopenicillin N synthase1.21.3.10.444
1i91INQCarbonic anhydrase 24.2.1.10.444
1qrtATPGlutamine--tRNA ligase6.1.1.180.444
1qv1CZHObelin/0.444
1x1dSAHC-20 methyltransferase/0.444
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2aot2PMHistamine N-methyltransferase2.1.1.80.444
2bsxNOSPurine nucleoside phosphorylase/0.444
2q92B23Methionine aminopeptidase/0.444
2y60M8FIsopenicillin N synthase1.21.3.10.444
2zc922UProthrombin3.4.21.50.444
3af1GDPPantothenate kinase2.7.1.330.444
3buvNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3cb2GDPTubulin gamma-1 chain/0.444
3dz2A8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.444
3iocA5DPantothenate synthetase6.3.2.10.444
3pqbVGPPutative oxidoreductase/0.444
3q43D66M1 family aminopeptidase3.4.110.444
3ugrIMNAldo-keto reductase family 1 member C3/0.444
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.444
4dyb0MHNucleoprotein/0.444
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.444
4l5b1UXDeoxycytidine kinase2.7.1.740.444
4li81XQTankyrase-12.4.2.300.444
4n1fCZHObelin/0.444
4ohwATPProtein clpf-1/0.444
4qx5CMPcGMP-dependent protein kinase 12.7.11.120.444
1amoFADNADPH--cytochrome P450 reductase/0.443
1eirBPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.443
1hzzNAPNAD(P) transhydrogenase subunit beta1.6.1.20.443
1pke2FDPurine nucleoside phosphorylase DeoD-type/0.443
1qinGIPLactoylglutathione lyase4.4.1.50.443
1qjfACSIsopenicillin N synthase1.21.3.10.443
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.443
1s36CEIObelin/0.443
2f3815MAldo-keto reductase family 1 member C3/0.443
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.443
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.443
2rc6FADFerredoxin--NADP reductase/0.443
2w6cBM4Acetylcholinesterase3.1.1.70.443
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3iu7FCDMethionine aminopeptidase 2/0.443
3ivxFG6Pantothenate synthetase6.3.2.10.443
3p9tTCLRepressor/0.443
3qfrFMNNADPH--cytochrome P450 reductase/0.443
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.443
3zcnATPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.443
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.443
4a83DXCMajor pollen allergen Bet v 1-A/0.443
4b4w9L9Bifunctional protein FolD/0.443
4b7zQ4QAcetylcholinesterase3.1.1.70.443
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.443
4du82P0Mevalonate diphosphate decarboxylase/0.443
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.443
4na4A1RPoly(ADP-ribose) glycohydrolase3.2.1.1430.443
4uthFMNXenobiotic reductase/0.443
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.443
4xbjIN5Alanine racemase, biosynthetic/0.443
1akaPLPAspartate aminotransferase, mitochondrial2.6.1.10.442
1blzACVIsopenicillin N synthase1.21.3.10.442
1ihiIU5Aldo-keto reductase family 1 member C2/0.442
1t3zCAOFormyl-CoA:oxalate CoA-transferase/0.442
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1yw7A41Methionine aminopeptidase 2/0.442
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.442
2clfF6FTryptophan synthase alpha chain/0.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2wd2MS5Carbonic anhydrase 24.2.1.10.442
2zsbADPPantothenate kinase2.7.1.330.442
3af2ACPPantothenate kinase2.7.1.330.442
3fhxPLPPyridoxal kinase2.7.1.350.442
3oadLPORenin3.4.23.150.442
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.442
3vg10GTBeta-secretase 13.4.23.460.442
3zkpERBErythromycin C-12 hydroxylase1.14.13.1540.442
4ax9N5NProthrombin3.4.21.50.442
4cukNAID-lactate dehydrogenase/0.442
4dbs0HVAldo-keto reductase family 1 member C3/0.442
4e0u0MVCyclic dipeptide N-prenyltransferase/0.442
4l0oPLPCystathionine gamma-synthase2.5.1.480.442
4zj8SUVOrexin receptor type 1/0.442
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.441
1e2nRCAThymidine kinase/0.441
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1stdBFSScytalone dehydratase4.2.1.940.441
1xq04TRCarbonic anhydrase 24.2.1.10.441
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2ed3SAHDiphthine synthase/0.441
2fb35ADGTP 3',8-cyclase4.1.99.180.441
2g1n1IGRenin3.4.23.150.441
2ga2A19Methionine aminopeptidase 2/0.441
2jb4A14Isopenicillin N synthase1.21.3.10.441
2pidYSATyrosine--tRNA ligase, mitochondrial6.1.1.10.441
2ydd2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
2z4sADPChromosomal replication initiator protein DnaA/0.441
2zevIPEGeranylgeranyl pyrophosphate synthase/0.441
3arvSAUChitinase A/0.441
3gwfNAPCyclohexanone monooxygenase/0.441
3mhlJ71Carbonic anhydrase 24.2.1.10.441
4arbC57Acetylcholinesterase3.1.1.70.441
4b1e6T6Beta-secretase 13.4.23.460.441
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4fhf0TTSpore photoproduct lyase/0.441
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.441
4q0kGA3Phytohormone-binding protein/0.441
4qfyDCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.441
4xo7ASDAldo-keto reductase family 1 member C2/0.441
5c1mCLRMu-type opioid receptor/0.441
6gsvGPSGlutathione S-transferase Mu 12.5.1.180.441
1e79ADPATP synthase subunit alpha, mitochondrial/0.440
1e79ADPATP synthase subunit beta, mitochondrial3.6.3.140.440
1lelBH7Avidin/0.440
1oknSTBCarbonic anhydrase 24.2.1.10.440
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.440
1rneC60Renin3.4.23.150.440
1s0jMUSTrans-sialidase/0.440
1ypeUIPProthrombin3.4.21.50.440
2c2aADPSensor histidine kinase/0.440
2g247IGRenin3.4.23.150.440
2g28TDKPyruvate dehydrogenase E1 component1.2.4.10.440
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.440
2vqbNAPPutative flavin-containing monooxygenase/0.440
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.440
2xvv9DNSerum albumin/0.440
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.440
3apwDP0Alpha-1-acid glycoprotein 2/0.440
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.440
3mjrAC2Deoxycytidine kinase2.7.1.740.440
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.440
3sxjSAMPutative methyltransferase/0.440
4a802ANMajor pollen allergen Bet v 1-A/0.440
4a84DXCMajor pollen allergen Bet v 1-A/0.440
4c2z646Glycylpeptide N-tetradecanoyltransferase 1/0.440
4cf7ADPAdenylate kinase/0.440
4do30LAFatty-acid amide hydrolase 13.5.1.990.440
4h3i10VBeta-secretase 13.4.23.460.440
4i4z2NE1,4-dihydroxy-2-naphthoyl-CoA synthase/0.440
4imfSI3N-acetylneuraminate lyase/0.440
4itp1GDCarbonic anhydrase 24.2.1.10.440
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.440
4xr9NADCalS8/0.440