sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 | 1.000 | |
| 2vj7 | VG6 | Beta-secretase 1 | 3.4.23.46 | 0.747 | |
| 2xfi | XFI | Beta-secretase 1 | 3.4.23.46 | 0.741 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.735 | |
| 2wf3 | ZY3 | Beta-secretase 1 | 3.4.23.46 | 0.707 | |
| 2vj9 | VG7 | Beta-secretase 1 | 3.4.23.46 | 0.699 | |
| 2viz | VG4 | Beta-secretase 1 | 3.4.23.46 | 0.697 | |
| 2xfj | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.680 | |
| 2vj6 | VG5 | Beta-secretase 1 | 3.4.23.46 | 0.677 | |
| 2vnn | CM7 | Beta-secretase 1 | 3.4.23.46 | 0.667 | |
| 2vnm | CM8 | Beta-secretase 1 | 3.4.23.46 | 0.658 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.635 | |
| 2vie | VG0 | Beta-secretase 1 | 3.4.23.46 | 0.629 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.617 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.610 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.597 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.596 | |
| 2wf2 | ZY2 | Beta-secretase 1 | 3.4.23.46 | 0.593 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.590 | |
| 2qzl | IXS | Beta-secretase 1 | 3.4.23.46 | 0.587 | |
| 3i25 | MV7 | Beta-secretase 1 | 3.4.23.46 | 0.578 | |
| 1tqf | 32P | Beta-secretase 1 | 3.4.23.46 | 0.576 | |
| 4gid | 0GH | Beta-secretase 1 | 3.4.23.46 | 0.572 | |
| 2is0 | I03 | Beta-secretase 1 | 3.4.23.46 | 0.570 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.568 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.565 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.554 | |
| 4fs4 | H24 | Beta-secretase 1 | 3.4.23.46 | 0.553 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.546 | |
| 2irz | I02 | Beta-secretase 1 | 3.4.23.46 | 0.545 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.544 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.541 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.535 | |
| 4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.530 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.524 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.522 | |
| 4frs | 0V6 | Beta-secretase 1 | 3.4.23.46 | 0.521 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.516 | |
| 4b00 | I6X | Beta-secretase 1 | 3.4.23.46 | 0.516 | |
| 4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.516 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.514 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.514 | |
| 4i0j | 842 | Beta-secretase 1 | 3.4.23.46 | 0.513 | |
| 3q70 | RIT | Candidapepsin-2 | 3.4.23.24 | 0.512 | |
| 2hm1 | LIQ | Beta-secretase 1 | 3.4.23.46 | 0.511 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.511 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.510 | |
| 4l7j | 1W2 | Beta-secretase 1 | 3.4.23.46 | 0.510 | |
| 1od1 | 0QS | Endothiapepsin | 3.4.23.22 | 0.509 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.506 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.506 | |
| 3prs | RIT | Endothiapepsin | 3.4.23.22 | 0.505 | |
| 1gvt | 2ZS | Endothiapepsin | 3.4.23.22 | 0.504 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.504 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.504 | |
| 4b70 | WM9 | Beta-secretase 1 | 3.4.23.46 | 0.501 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.500 | |
| 4l7g | 1W0 | Beta-secretase 1 | 3.4.23.46 | 0.500 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.500 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.499 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.498 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.497 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.494 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.494 | |
| 3t6i | NC9 | Endothiapepsin | 3.4.23.22 | 0.493 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.493 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.493 | |
| 4m6j | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.493 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.491 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.490 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.489 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.489 | |
| 1w51 | L01 | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
| 3pb5 | F63 | Endothiapepsin | 3.4.23.22 | 0.488 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.488 | |
| 4zea | IMI | Endothiapepsin | 3.4.23.22 | 0.487 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.485 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.485 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 3pi5 | 3P5 | Beta-secretase 1 | 3.4.23.46 | 0.484 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.484 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.483 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.482 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.481 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.481 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.481 | |
| 2viy | VG3 | Beta-secretase 1 | 3.4.23.46 | 0.481 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.481 | |
| 4y3r | F06 | Endothiapepsin | 3.4.23.22 | 0.481 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.480 | |
| 4ef4 | C2E | Stimulator of interferon genes protein | / | 0.480 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.478 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.478 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.478 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.478 | |
| 3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 3oag | LPQ | Renin | 3.4.23.15 | 0.477 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.477 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.477 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.476 | |
| 1ra8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.475 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.475 | |
| 1ra3 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.474 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.474 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.474 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.474 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.474 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.473 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.473 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 2pb6 | SAH | Diphthine synthase | / | 0.473 | |
| 3mzh | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.473 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.472 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.472 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.472 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.472 | |
| 1gvw | 0EM | Endothiapepsin | 3.4.23.22 | 0.471 | |
| 1ppl | 1Z7 | Penicillopepsin-1 | 3.4.23.20 | 0.471 | |
| 4jay | NAP | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.471 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.471 | |
| 1c9k | 5GP | Bifunctional adenosylcobalamin biosynthesis protein CobU | / | 0.470 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.470 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.470 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
| 2b37 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.470 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.470 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.470 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.470 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.470 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.469 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.469 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.469 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.469 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.469 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.469 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.469 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.468 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.468 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 2yd0 | BES | Endoplasmic reticulum aminopeptidase 1 | 3.4.11 | 0.468 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.468 | |
| 5d3q | GDP | Dynamin-1 | 3.6.5.5 | 0.468 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.467 | |
| 3g2h | KOT | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.467 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.467 | |
| 3pmu | F7L | Endothiapepsin | 3.4.23.22 | 0.467 | |
| 4e2x | TYD | Methyltransferase | / | 0.467 | |
| 4jic | FMN | GTN Reductase | / | 0.467 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.466 | |
| 2emu | SAH | Diphthine synthase | / | 0.466 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.466 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.466 | |
| 2pb4 | SAH | Diphthine synthase | / | 0.466 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.466 | |
| 5ein | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.466 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 2ilv | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.465 | |
| 2z3l | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.465 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.465 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 3w8d | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.465 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.465 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.465 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.464 | |
| 1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.464 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.464 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.464 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.464 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.464 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.464 | |
| 4ype | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.464 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 2wed | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.463 | |
| 4blr | UTP | NTPase P4 | / | 0.463 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.463 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.463 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.462 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.462 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.462 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.462 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.462 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.462 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.461 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.461 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.461 | |
| 2hux | SAH | Diphthine synthase | / | 0.461 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.461 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.461 | |
| 3ppr | 4CS | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.461 | |
| 4b78 | KGG | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.460 | |
| 2ztm | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.460 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.460 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.460 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.460 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.459 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.459 | |
| 2dsg | SAH | Diphthine synthase | / | 0.459 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.459 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.459 | |
| 2g9v | IFM | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.459 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.459 | |
| 3eks | CY9 | Actin-5C | / | 0.459 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.459 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.459 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.459 | |
| 4lxm | 1YU | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 1icu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.458 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
| 2nni | MTK | Cytochrome P450 2C8 | / | 0.458 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.458 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.458 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.458 | |
| 1dds | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.457 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.457 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 3ai3 | NDP | NADPH-sorbose reductase | / | 0.457 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.457 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.457 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.457 | |
| 4i9n | 1E5 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.456 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2b8l | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.456 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.456 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.456 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.456 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.456 | |
| 3kmx | G00 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.456 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.456 | |
| 4d89 | BXD | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4f9g | C2E | Stimulator of interferon genes protein | / | 0.456 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.456 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.456 | |
| 4lcj | NAD | C-terminal-binding protein 2 | / | 0.456 | |
| 1iy8 | NAD | Levodione reductase | / | 0.455 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.455 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.455 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.455 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.455 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.455 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.455 | |
| 3ljt | LA3 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.455 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.455 | |
| 4fsl | 0VB | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.455 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.454 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 1p4a | PCP | Pur operon repressor | / | 0.454 | |
| 1ra3 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.454 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.454 | |
| 2en5 | SAH | Diphthine synthase | / | 0.454 | |
| 2fto | TMP | Thymidylate synthase | / | 0.454 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.454 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.454 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 3pi0 | F91 | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 4dmm | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.454 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 5dmh | ADP | 3-oxo-tetronate kinase | / | 0.454 | |
| 5itz | GTP | Tubulin alpha-1B chain | / | 0.454 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.453 | |
| 1omo | NAD | Alanine dehydrogenase | / | 0.453 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 1yki | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.453 | |
| 2b53 | D23 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.453 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.453 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.453 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.453 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.453 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.453 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.453 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.453 | |
| 3up5 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.453 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.453 | |
| 4dd8 | BAT | Disintegrin and metalloproteinase domain-containing protein 8 | 3.4.24 | 0.453 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.453 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.453 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.453 | |
| 1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.452 | |
| 1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.452 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.452 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.452 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.452 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.452 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.452 | |
| 2q3e | NAI | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.452 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.452 | |
| 2zry | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.452 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.452 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3o0q | ADN | Vitamin B12-dependent ribonucleotide reductase | / | 0.452 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.452 | |
| 4fpy | 0V8 | Sialidase B | 3.2.1.18 | 0.452 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.452 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.452 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.451 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.451 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.451 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2fre | FMN | NAD(P)H-flavin oxidoreductase | / | 0.451 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 2xfy | ACX | Beta-amylase | 3.2.1.2 | 0.451 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.451 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.451 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.451 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.451 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.451 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.451 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.450 | |
| 1dyj | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1g5q | ASP_SER_TYR_THR_CYS | Epidermin decarboxylase | 4.1.1 | 0.450 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.450 | |
| 1m8k | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.450 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.450 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.450 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.450 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.450 | |
| 2ejz | SAH | Diphthine synthase | / | 0.450 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.450 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 2z3n | PHE_ARG_TYR_LEU_GLY | Leucyl/phenylalanyl-tRNA--protein transferase | 2.3.2.6 | 0.450 | |
| 3ai2 | NDP | NADPH-sorbose reductase | / | 0.450 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3hyg | 099 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.450 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.450 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.450 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.450 | |
| 4e2d | FMN | Dehydrogenase | / | 0.450 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.450 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.450 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.450 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.450 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.450 | |
| 1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.449 | |
| 1q6s | 214 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.449 | |
| 1w6j | R71 | Lanosterol synthase | 5.4.99.7 | 0.449 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.449 | |
| 2b4q | NAP | Rhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.449 | |
| 2e8q | SAH | Diphthine synthase | / | 0.449 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.449 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.449 | |
| 2rcy | NAP | Pyrroline-5-carboxylate reductase | / | 0.449 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.449 | |
| 3pld | F90 | Endothiapepsin | 3.4.23.22 | 0.449 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.449 | |
| 3tr0 | 5GP | Guanylate kinase | / | 0.449 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.449 | |
| 3vye | VYE | Renin | 3.4.23.15 | 0.449 | |
| 4b77 | 54M | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4y3j | HIC | Endothiapepsin | 3.4.23.22 | 0.449 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1xgi | NST | Beta-lactamase | 3.5.2.6 | 0.448 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.448 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.448 | |
| 2p6l | SAH | Diphthine synthase | / | 0.448 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.448 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.448 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.448 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.448 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4gtm | 7TM | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.448 | |
| 4usr | FAD | Monooxygenase | / | 0.448 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.448 | |
| 5fwn | NAP | Putative dehydrogenase | / | 0.448 | |
| 1f8f | NAD | Benzyl alcohol dehydrogenase | / | 0.447 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.447 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 2a1o | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.447 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.447 | |
| 2e17 | SAH | Diphthine synthase | / | 0.447 | |
| 2ed5 | SAH | Diphthine synthase | / | 0.447 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.447 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.447 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.447 | |
| 3n14 | FMN | Xenobiotic reductase | / | 0.447 | |
| 3pbz | F02 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 3wb2 | YGP | Uncharacterized protein MJ0488 | / | 0.447 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.447 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.447 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.447 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.447 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.446 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1owe | 675 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.446 | |
| 1ri1 | GTG | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.446 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.446 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.446 | |
| 2e83 | FMN | FMN-binding protein | / | 0.446 | |
| 2emr | SAH | Diphthine synthase | / | 0.446 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.446 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.446 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.446 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.446 | |
| 3mp3 | HGG | Hydroxymethylglutaryl-CoA lyase, mitochondrial | 4.1.3.4 | 0.446 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3ut5 | LOC | Tubulin beta chain | / | 0.446 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.446 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.446 | |
| 4nd2 | A3D | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.446 | |
| 4xr9 | NAD | CalS8 | / | 0.446 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.445 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.445 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.445 | |
| 2e4n | SAH | Diphthine synthase | / | 0.445 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.445 | |
| 2hut | SAH | Diphthine synthase | / | 0.445 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.445 | |
| 2oc4 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.445 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.445 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.445 | |
| 3ieu | GDP | GTPase Era | / | 0.445 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.445 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 4l4x | NDP | AmphI | / | 0.445 | |
| 4uoc | NCN | CinA-like protein | / | 0.445 | |
| 4y57 | F63 | Endothiapepsin | 3.4.23.22 | 0.445 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.445 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.444 | |
| 1kp3 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.444 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.444 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.444 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.444 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.444 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.444 | |
| 3kji | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.444 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 3pw8 | ACO | 1,2-phenylacetyl-CoA epoxidase, subunit A | 1.14.13.149 | 0.444 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3w2j | QRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.444 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.444 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.444 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.444 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.444 | |
| 1gvv | 0GM | Endothiapepsin | 3.4.23.22 | 0.443 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.443 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1y7l | ASN_LEU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.443 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 2c1z | U2F | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.443 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.443 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.443 | |
| 3akz | GSU | Glutamate--tRNA ligase 2 | / | 0.443 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.443 | |
| 3p0h | FSE | Putative tyrosyl-tRNA synthetase | / | 0.443 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.443 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.443 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.443 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.443 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.443 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 4x5i | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.443 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1gad | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.442 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.442 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.442 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.442 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.442 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.442 | |
| 1rb2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.442 | |
| 2e16 | SAH | Diphthine synthase | / | 0.442 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.442 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3h2c | B58 | Dihydropteroate synthase | / | 0.442 | |
| 3o0o | 5AD | Vitamin B12-dependent ribonucleotide reductase | / | 0.442 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.442 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.442 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.442 | |
| 4qai | FMN | NADPH dehydrogenase | / | 0.442 | |
| 4x5h | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.441 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1owd | 497 | Urokinase-type plasminogen activator | 3.4.21.73 | 0.441 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 1vik | BAY | Gag-Pol polyprotein | / | 0.441 | |
| 2bri | ANP | Uridylate kinase | 2.7.4.22 | 0.441 | |
| 2dv4 | SAH | Diphthine synthase | / | 0.441 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.441 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.441 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.441 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.441 | |
| 2hdj | NDP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.441 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.441 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.441 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.441 | |
| 3f8w | ADN | Purine nucleoside phosphorylase | / | 0.441 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.441 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.441 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4k5o | 1OT | M1 family aminopeptidase | 3.4.11 | 0.441 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.441 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.441 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.441 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.440 | |
| 1dr2 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1eag | A70 | Candidapepsin-2 | 3.4.23.24 | 0.440 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.440 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.440 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.440 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2b4y | APR | NAD-dependent protein deacylase sirtuin-5, mitochondrial | / | 0.440 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.440 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.440 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.440 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.440 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3daa | PDD | D-alanine aminotransferase | 2.6.1.21 | 0.440 | |
| 3e6e | DCS | Alanine racemase | / | 0.440 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.440 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.440 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.440 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.440 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.440 | |
| 3uth | GDU | UDP-galactopyranose mutase | / | 0.440 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.440 | |
| 3w8e | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.440 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.440 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.440 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.440 | |
| 4oug | LP5 | Peptidoglycan recognition protein 1 | / | 0.440 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.440 | |
| 5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.440 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.440 |