sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.855 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.831 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.828 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.826 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.825 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.819 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.818 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.812 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.809 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.803 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.795 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.780 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.779 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.766 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.750 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.737 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.719 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.702 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.687 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.655 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.634 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.619 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.615 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.608 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.603 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.602 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.598 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.598 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.592 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.591 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.576 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.572 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.564 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.562 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.561 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.553 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.537 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.528 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.520 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.519 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.509 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.497 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.497 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.496 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.493 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.493 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.492 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.491 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.490 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.490 | |
| 1uxj | NAD | Malate dehydrogenase | / | 0.489 | |
| 3eku | CY9 | Actin-5C | / | 0.489 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.488 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.488 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.488 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.488 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.487 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.485 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.484 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.483 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.482 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.480 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.479 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.478 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.478 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.478 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.477 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.477 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.476 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.475 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.475 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.474 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.474 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.474 | |
| 2wya | HMG | Hydroxymethylglutaryl-CoA synthase, mitochondrial | 2.3.3.10 | 0.473 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.473 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.473 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.473 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.473 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.472 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.472 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.472 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.472 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.472 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 4iae | 1DX | Alr2278 protein | / | 0.472 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.471 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.471 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.471 | |
| 1pwu | GM6 | Lethal factor | 3.4.24.83 | 0.470 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.470 | |
| 5hwo | HMG | Hydroxymethylglutaryl-CoA synthase | / | 0.470 | |
| 1e2n | RCA | Thymidine kinase | / | 0.469 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.469 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.469 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.469 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.469 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.469 | |
| 4n1g | CEI | Obelin | / | 0.469 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.468 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.468 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.468 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.468 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.468 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.467 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.467 | |
| 2a9z | 26A | Adenosine kinase | 2.7.1.20 | 0.467 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.467 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 5c1g | GDU | Histo-blood group ABO system transferase | / | 0.467 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.467 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.466 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.466 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3e6e | DCS | Alanine racemase | / | 0.466 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.466 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.465 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.465 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.465 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.465 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.464 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.464 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.464 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.464 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.464 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.463 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.463 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.463 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.463 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.463 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3gvh | NAD | Malate dehydrogenase | / | 0.463 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.463 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.463 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.463 | |
| 1h74 | AGS | Homoserine kinase | 2.7.1.39 | 0.462 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.462 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.462 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.462 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.462 | |
| 3vax | PLP | Uncharacterized protein | / | 0.462 | |
| 4iah | 1DX | Alr2278 protein | / | 0.462 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.462 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.461 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.461 | |
| 1kfb | IGP | Tryptophan synthase alpha chain | / | 0.461 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.461 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.461 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.461 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.461 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.460 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 2bkt | RPF | Renin | 3.4.23.15 | 0.460 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.460 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.460 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.460 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.460 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.460 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.460 | |
| 4cjf | RVN | Integrase | / | 0.460 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.460 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.460 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1kt8 | ILP | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.459 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.459 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.459 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.458 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.458 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.458 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.458 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.458 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.458 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.458 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.458 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.458 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.458 | |
| 3w5h | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.458 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.458 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.457 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.457 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.457 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.456 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.456 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.456 | |
| 2ggs | NDP | dTDP-4-dehydrorhamnose reductase | / | 0.456 | |
| 2npx | NAD | NADH peroxidase | 1.11.1.1 | 0.456 | |
| 2ohv | NHL | Glutamate racemase | / | 0.456 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.456 | |
| 3a6r | FMN | FMN-binding protein | / | 0.456 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.456 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.456 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.456 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.456 | |
| 3wag | TYD | Glycosyltransferase | / | 0.456 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4rww | 2BA | Lmo2692 protein | / | 0.456 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.456 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.455 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.455 | |
| 1s36 | CEI | Obelin | / | 0.455 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.455 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.455 | |
| 4f1y | CNI | Glutamate receptor 3 | / | 0.455 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.455 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.455 | |
| 5k5z | ANP | Uncharacterized protein | / | 0.455 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.455 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.454 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.454 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.454 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.454 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.454 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.454 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.454 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.454 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.453 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.453 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.453 | |
| 1u4o | NDD | L-lactate dehydrogenase | 1.1.1.27 | 0.453 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.453 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.453 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.453 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.453 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.453 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.453 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3oes | GNP | GTPase RhebL1 | / | 0.453 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.453 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.453 | |
| 1c7o | PPG | Hemolysin | / | 0.452 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.452 | |
| 1qy8 | RDI | Endoplasmin | / | 0.452 | |
| 1wua | AP8 | Actin, alpha skeletal muscle | / | 0.452 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.452 | |
| 2ahr | NAP | Pyrroline-5-carboxylate reductase | / | 0.452 | |
| 2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.452 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.452 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.452 | |
| 3eks | CY9 | Actin-5C | / | 0.452 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.452 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.452 | |
| 3tl1 | JRO | Putative polyketide cyclase | / | 0.452 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.452 | |
| 3v2u | ATP | Protein GAL3 | / | 0.452 | |
| 3w77 | FMN | FMN-dependent NADH-azoreductase | / | 0.452 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.452 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.452 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.452 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.452 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.452 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.451 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.451 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.451 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.451 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.451 | |
| 2r2l | PB9 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.451 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 3vdq | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.451 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.451 | |
| 4y1b | NAP | AntE | / | 0.451 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.450 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.450 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.450 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.450 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.450 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.450 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.450 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1k5d | GNP | GTP-binding nuclear protein Ran | / | 0.449 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.449 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.449 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.449 | |
| 2iml | FMN | Uncharacterized protein | / | 0.449 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.449 | |
| 2x8i | X8I | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.449 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.449 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.449 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.449 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.449 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.449 | |
| 3w1q | YRO | Dihydroorotate dehydrogenase (fumarate) | 1.3.98.1 | 0.449 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.449 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.449 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.449 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.449 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.448 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1sa5 | BMV | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.448 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.448 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.448 | |
| 3fpj | SAM | Uncharacterized protein | / | 0.448 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.448 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.448 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.448 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.448 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.448 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.448 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.448 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.448 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.448 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.448 | |
| 4rel | KMP | Glycosyltransferase | / | 0.448 | |
| 4ybr | NAP | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.448 | |
| 5dp2 | NAP | CurF | / | 0.448 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1hyg | NAP | L-2-hydroxycarboxylate dehydrogenase (NAD(P)(+)) | / | 0.447 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.447 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.447 | |
| 1wze | NAD | Malate dehydrogenase | / | 0.447 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.447 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.447 | |
| 2ofi | ADK | 3-methyladenine DNA glycosylase I | / | 0.447 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.447 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.447 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.447 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.447 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.447 | |
| 4e2b | FMN | Dehydrogenase | / | 0.447 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.447 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4jic | FMN | GTN Reductase | / | 0.447 | |
| 4m49 | 22Y | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4wfr | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.447 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.447 | |
| 5dw5 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 1akc | PPE | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.446 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.446 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 1uhh | CZP | Aequorin-2 | / | 0.446 | |
| 1wk8 | VMS | Isoleucine--tRNA ligase | 6.1.1.5 | 0.446 | |
| 2bxf | DZP | Serum albumin | / | 0.446 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.446 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.446 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.446 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.446 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.446 | |
| 3e30 | ED4 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.446 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.446 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.446 | |
| 1kap | GLY_SER_ASN_SER | Serralysin | 3.4.24.40 | 0.445 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 2c4j | GSO | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.445 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.445 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.445 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.445 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.445 | |
| 4df2 | FMN | NADPH dehydrogenase | / | 0.445 | |
| 4g3p | UD1 | Bifunctional protein GlmU | / | 0.445 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.445 | |
| 4ha9 | NDP | 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase | 1.1.1.302 | 0.445 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.445 | |
| 5a3b | APR | SIR2 family protein | / | 0.445 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.444 | |
| 1k8y | 13P | Tryptophan synthase alpha chain | / | 0.444 | |
| 1phq | FPE | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.444 | |
| 1qxo | FMN | Chorismate synthase | / | 0.444 | |
| 1wn3 | HXC | Phenylacetic acid degradation protein PaaI | / | 0.444 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.444 | |
| 2e15 | SAH | Diphthine synthase | / | 0.444 | |
| 2emr | SAH | Diphthine synthase | / | 0.444 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.444 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.444 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.444 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.444 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.444 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.444 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3mkn | DNB | Pyrimidine-specific ribonucleoside hydrolase RihB | / | 0.444 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.444 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.444 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.444 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.444 | |
| 4c36 | ZO9 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.444 | |
| 4h6k | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.444 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.444 | |
| 5hwp | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.444 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.443 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.443 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.443 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.443 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.443 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.443 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.443 | |
| 2bb3 | SAH | Cobalamin biosynthesis precorrin-6Y methylase (CbiE) | / | 0.443 | |
| 2e83 | FMN | FMN-binding protein | / | 0.443 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.443 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.443 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.443 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.443 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.443 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.443 | |
| 3pe2 | E1B | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.443 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 4e2d | FMN | Dehydrogenase | / | 0.443 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.443 | |
| 4loi | 1YC | Stimulator of interferon genes protein | / | 0.443 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 1hku | NAD | C-terminal-binding protein 1 | 1.1.1 | 0.442 | |
| 1hnc | GDN | Glutathione S-transferase Mu 2 | 2.5.1.18 | 0.442 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.442 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.442 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.442 | |
| 1t2c | NAI | L-lactate dehydrogenase | 1.1.1.27 | 0.442 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.442 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.442 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2v34 | CTN | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.442 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.442 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.442 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.442 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.442 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.442 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.442 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.441 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.441 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2gtb | AZP | Orf1ab polyprotein | / | 0.441 | |
| 2ome | NAD | C-terminal-binding protein 2 | / | 0.441 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.441 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.441 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.441 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.441 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.441 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.441 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.441 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.441 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.441 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 3ppo | DCK | Glycine betaine/carnitine/choline-binding protein OpuCC | / | 0.441 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.441 | |
| 3tgy | ASC | Lactoperoxidase | 1.11.1.7 | 0.441 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.441 | |
| 4ho4 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.441 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.441 | |
| 4u7w | NDP | MxaA | / | 0.441 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.441 | |
| 1guy | NAD | Malate dehydrogenase | / | 0.440 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.440 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.440 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.440 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.440 | |
| 3faz | NOS | Purine nucleoside phosphorylase | / | 0.440 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.440 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.440 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.440 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4a3u | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.440 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 4bqp | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.440 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.440 | |
| 4i9h | 1E4 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 4jin | 1L7 | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.440 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.440 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.440 | |
| 4rvd | SAM | D-mycarose 3-C-methyltransferase | / | 0.440 | |
| 4yvj | SFG | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.440 |