sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.934 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.885 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.882 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.875 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.837 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.835 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.828 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.824 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.820 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.818 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.815 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.806 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.780 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.765 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.765 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.762 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.761 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.757 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.744 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.739 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.735 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.733 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.725 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.722 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.722 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.718 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.713 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.704 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.703 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.697 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.696 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.695 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.694 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.693 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.690 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.686 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.683 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.679 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.674 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.665 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.660 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.624 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.612 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.608 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.599 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.588 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.575 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.567 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.564 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.562 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.561 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.556 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.555 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.553 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.534 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.533 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.531 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.530 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.522 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.521 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.521 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.517 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.512 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.511 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.510 | |
| 4iae | 1DX | Alr2278 protein | / | 0.508 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.507 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.497 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.497 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.497 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.495 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.494 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.494 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.491 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.491 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.491 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.490 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.490 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.489 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.487 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.485 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.485 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.484 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.484 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.484 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.482 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.481 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.481 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.480 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.480 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.479 | |
| 4iah | 1DX | Alr2278 protein | / | 0.479 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.478 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.477 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.477 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.477 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.477 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.476 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.476 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.476 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.475 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.475 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.475 | |
| 4jic | FMN | GTN Reductase | / | 0.474 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.474 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.473 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 2vte | IK4 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.472 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.472 | |
| 3e6e | DCS | Alanine racemase | / | 0.472 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.472 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.472 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.472 | |
| 4tmb | FMN | Old yellow enzyme | / | 0.472 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.471 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.471 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.471 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.471 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.470 | |
| 3zht | TD9 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.470 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.470 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.469 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.469 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.469 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.469 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2xpc | 051 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.469 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.469 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.468 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.468 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.468 | |
| 3oet | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.468 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.468 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.467 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.467 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.467 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.466 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.466 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.466 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.465 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.465 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.465 | |
| 3ivg | FG5 | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.465 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.465 | |
| 4rnw | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.465 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.465 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.464 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.464 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.464 | |
| 2e77 | FMN | Lactate oxidase | / | 0.464 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.464 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.464 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.464 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.464 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 3zhs | TD6 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.464 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.464 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.464 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.463 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.463 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 3kru | FMN | NADH:flavin oxidoreductase/NADH oxidase | / | 0.463 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.463 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.462 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.462 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.462 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.462 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.462 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.461 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.461 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.461 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.461 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.461 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.460 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.460 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.460 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3hgr | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.460 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.459 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.459 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.459 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.459 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.459 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.459 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.459 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.458 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.458 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.458 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.458 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.458 | |
| 3lu1 | UD2 | UDP-N-acetylglucosamine 4-epimerase | / | 0.458 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.458 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.458 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.458 | |
| 4e2d | FMN | Dehydrogenase | / | 0.458 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.458 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.458 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.457 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.457 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.457 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.457 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.457 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.457 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.457 | |
| 3hgs | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.457 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.457 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.457 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.457 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.456 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.456 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.456 | |
| 2gst | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.456 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.456 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.456 | |
| 1eio | GCH | Gastrotropin | / | 0.455 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.455 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.455 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.455 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.455 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.454 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.454 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.454 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.454 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.454 | |
| 3hdq | GDU | UDP-galactopyranose mutase | / | 0.454 | |
| 3vp6 | HLD | Glutamate decarboxylase 1 | 4.1.1.15 | 0.454 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.454 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.454 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 1e2n | RCA | Thymidine kinase | / | 0.453 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.453 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 2i7n | ACO | Pantothenate kinase 1 | 2.7.1.33 | 0.453 | |
| 3hf3 | FMN | Chromate reductase | / | 0.453 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.453 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.453 | |
| 3zw9 | NAD | Peroxisomal bifunctional enzyme | 1.1.1.35 | 0.453 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.453 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.453 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.453 | |
| 1ee9 | NAD | Methylenetetrahydrofolate dehydrogenase [NAD(+)] | 1.5.1.15 | 0.452 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.452 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.452 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.452 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.452 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.452 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.451 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.451 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2gqa | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.451 | |
| 2ylt | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3isj | A8D | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.451 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.451 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.451 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.451 | |
| 1gpd | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.12 | 0.450 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 1z44 | FMN | NADPH dehydrogenase | / | 0.450 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2vtd | LKM | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.450 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.450 | |
| 3v2u | ATP | Protein GAL3 | / | 0.450 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.450 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.450 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.450 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.450 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.450 | |
| 5bv3 | M7G | m7GpppX diphosphatase | 3.6.1.59 | 0.450 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.449 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.449 | |
| 2ohv | NHL | Glutamate racemase | / | 0.449 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.449 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.449 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.449 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.449 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.449 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.449 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4cf6 | CBD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.449 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.449 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.448 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1m9a | GTX | Glutathione S-transferase class-mu 26 kDa isozyme | 2.5.1.18 | 0.448 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.448 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.448 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.448 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.448 | |
| 3gst | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.448 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.448 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.447 | |
| 1kc1 | NDP | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.447 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.447 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.447 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.447 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.447 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.447 | |
| 2b4d | COA | Diamine acetyltransferase 1 | / | 0.447 | |
| 2qc8 | ADP | Glutamine synthetase | 6.3.1.2 | 0.447 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.447 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.447 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.447 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.447 | |
| 4e2b | FMN | Dehydrogenase | / | 0.447 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.447 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.446 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.446 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 1s64 | 778 | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.446 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.446 | |
| 3fvl | BHK | Carboxypeptidase A1 | 3.4.17.1 | 0.446 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 4ddh | MS0 | Pantothenate synthetase | 6.3.2.1 | 0.446 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.446 | |
| 4lut | DCS | Alanine racemase | / | 0.446 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.445 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.445 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.445 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.445 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.445 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2fy4 | COA | Choline O-acetyltransferase | 2.3.1.6 | 0.445 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.445 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.445 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.445 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.445 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3kp4 | MII | Transcriptional regulator TcaR | / | 0.445 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.445 | |
| 3nut | SAH | Precorrin-3 methylase | / | 0.445 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.445 | |
| 3wag | TYD | Glycosyltransferase | / | 0.445 | |
| 4fhj | 0TZ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.445 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.444 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.444 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.444 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.444 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.444 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.444 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.444 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.444 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.444 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.444 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.444 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.444 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.444 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.444 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.444 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.444 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.444 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.444 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.444 | |
| 4rel | KMP | Glycosyltransferase | / | 0.444 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.444 | |
| 5cyo | GDP | Septin-9 | / | 0.444 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.444 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2pk3 | A2R | GDP-6-deoxy-D-mannose reductase | / | 0.443 | |
| 3axk | NDP | Ribulose bisphosphate carboxylase large chain | 4.1.1.39 | 0.443 | |
| 3ei8 | PL5 | LL-diaminopimelate aminotransferase, chloroplastic | / | 0.443 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.443 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.443 | |
| 3wyc | NAP | Meso-diaminopimelate D-dehydrogenase | 1.4.1.16 | 0.443 | |
| 4e2z | JHZ | Methyltransferase | / | 0.443 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 4mdh | NAD | Malate dehydrogenase, cytoplasmic | 1.1.1.37 | 0.443 | |
| 4n1g | CEI | Obelin | / | 0.443 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.443 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.442 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.442 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 1kap | GLY_SER_ASN_SER | Serralysin | 3.4.24.40 | 0.442 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.442 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.442 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.442 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.442 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.442 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.442 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.442 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.442 | |
| 1ci0 | FMN | Pyridoxamine 5'-phosphate oxidase | 1.4.3.5 | 0.441 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.441 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.441 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.441 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.441 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.441 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.441 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.441 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.441 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.441 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 3dgq | EAA | Glutathione S-transferase P | 2.5.1.18 | 0.441 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.441 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.441 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.441 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.441 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 4jlm | 1NN | Deoxycytidine kinase | 2.7.1.74 | 0.441 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.441 | |
| 4xr9 | NAD | CalS8 | / | 0.441 | |
| 4yj2 | GTP | Tubulin alpha-1B chain | / | 0.441 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.441 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.440 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.440 | |
| 1esn | ANP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 1gal | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 1qr6 | NAD | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.440 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.440 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.440 | |
| 2qn3 | F55 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.440 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.440 | |
| 2yj4 | ATP | Copper-transporting ATPase | / | 0.440 | |
| 2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.440 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.440 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.440 | |
| 3p8j | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4h6p | FMN | Chromate reductase | / | 0.440 | |
| 4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 | |
| 4tqg | NDP | Putative dTDP-d-glucose 4 6-dehydratase | / | 0.440 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.440 |