sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.698 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.666 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.631 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.607 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.582 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.577 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.577 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.573 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.566 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.560 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.557 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.556 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.554 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.552 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.550 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.546 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.545 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.544 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.543 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.542 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.539 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.535 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.532 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.532 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.530 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.528 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.526 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.522 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.520 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.513 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.510 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.509 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.509 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.508 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.508 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.507 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.500 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.500 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.499 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.496 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.495 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.494 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.494 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.493 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.492 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.491 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.490 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.490 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.490 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.490 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.490 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.490 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.489 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.489 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.489 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.488 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.488 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.486 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.486 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.486 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.486 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.485 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.485 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.485 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.484 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.484 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.484 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.484 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.484 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.483 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.483 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.482 | |
| 1swt | BTN | Streptavidin | / | 0.482 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.482 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.482 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.481 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.481 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.481 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.480 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 3da2 | 4MD | Carbonic anhydrase 13 | 4.2.1.1 | 0.480 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.480 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.479 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.479 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.479 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.479 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.478 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.478 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.478 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.478 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.476 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.476 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 4iae | 1DX | Alr2278 protein | / | 0.476 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.475 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.475 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.474 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.474 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.474 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.473 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.473 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.473 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.473 | |
| 4h6p | FMN | Chromate reductase | / | 0.473 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.472 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.472 | |
| 4lxj | LAN | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.472 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.472 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.471 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.471 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.471 | |
| 4rh1 | 0TT | Spore photoproduct lyase | / | 0.471 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.470 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.470 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.470 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.470 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.470 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.470 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.469 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.469 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.469 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.469 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.468 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.468 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.468 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.468 | |
| 2vut | NAD | Nitrogen metabolite repression protein nmrA | / | 0.467 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.467 | |
| 3m30 | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.467 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.467 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.467 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
| 1i9h | BNI | Streptavidin | / | 0.466 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.466 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.465 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.465 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.465 | |
| 3m1v | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.465 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.464 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.464 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.464 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.464 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.464 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.463 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.463 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.463 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.463 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.463 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
| 4jic | FMN | GTN Reductase | / | 0.463 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.462 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.462 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.462 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.462 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.462 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.462 | |
| 4gl4 | NAI | Alcohol dehydrogenase class-3 | / | 0.462 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.462 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.461 | |
| 1ppj | ANY | Cytochrome b | / | 0.461 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 2r59 | PH0 | Leukotriene A-4 hydrolase | 3.3.2.6 | 0.461 | |
| 2rte | BTN | Streptavidin | / | 0.461 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.461 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.461 | |
| 4iah | 1DX | Alr2278 protein | / | 0.461 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.461 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.460 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.460 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.460 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.460 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.460 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.460 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.460 | |
| 3pqb | VGP | Putative oxidoreductase | / | 0.460 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.460 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.459 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.459 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.459 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 2rtd | BTN | Streptavidin | / | 0.459 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.459 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.459 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.459 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.459 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.459 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.459 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.459 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.459 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.459 | |
| 4xo7 | ASD | Aldo-keto reductase family 1 member C2 | / | 0.459 | |
| 5dp2 | NAP | CurF | / | 0.459 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.458 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.458 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.458 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.458 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.458 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.458 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.458 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.458 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.458 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.458 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.458 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.458 | |
| 4oe4 | NAD | Delta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial | 1.2.1.88 | 0.458 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.457 | |
| 1sre | HAB | Streptavidin | / | 0.457 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.457 | |
| 3ewk | FAD | Sensory box histidine kinase/response regulator | / | 0.457 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.457 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.457 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.457 | |
| 4jzr | 4JR | Egl nine homolog 1 | / | 0.457 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.457 | |
| 4xwt | U5P | Ribonuclease J | / | 0.457 | |
| 1eio | GCH | Gastrotropin | / | 0.456 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 3d5q | T30 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.456 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.456 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.455 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.455 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.455 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.455 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.454 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.454 | |
| 2flh | ZEA | Cytokinin-specific binding protein | / | 0.454 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.454 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.454 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.454 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.454 | |
| 4jv4 | 1OR | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.454 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.454 | |
| 5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.454 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.454 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.453 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.453 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.453 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.453 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.453 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.452 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.452 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.452 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.452 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.452 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.452 | |
| 3m2u | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.452 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.452 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.452 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.452 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.452 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.452 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.451 | |
| 1q23 | FUA | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.451 | |
| 1thy | UMP | Thymidylate synthase | / | 0.451 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.451 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.451 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.451 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.451 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.451 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.451 | |
| 3p5p | A3C | Taxadiene synthase | 4.2.3.17 | 0.451 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.451 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.451 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.451 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.450 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.450 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.450 | |
| 2a5c | 8DA | Avidin | / | 0.450 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.450 | |
| 2c4i | BTN | Avidin | / | 0.450 | |
| 2eit | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.450 | |
| 2hun | NAD | 336aa long hypothetical dTDP-glucose 4,6-dehydratase | / | 0.450 | |
| 2j41 | 5GP | Guanylate kinase | / | 0.450 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.450 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.450 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.450 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.450 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.450 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.450 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4ejv | LCL | Transcriptional regulator TcaR | / | 0.450 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.450 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.450 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.450 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.450 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.449 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.449 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 2acw | UPG | Glycosyltransferase | / | 0.449 | |
| 2rto | IMI | Streptavidin | / | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.449 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.449 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.449 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.449 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 4e2z | JHZ | Methyltransferase | / | 0.449 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.448 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.448 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.448 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.448 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.448 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.448 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.448 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.448 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.448 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.448 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.448 | |
| 3lzz | GDP | Uncharacterized protein | / | 0.448 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.448 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.448 | |
| 4bzn | UGX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.448 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.448 | |
| 1avd | BTN | Avidin | / | 0.447 | |
| 1ege | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.447 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 1oxo | IK2 | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.447 | |
| 1stp | BTN | Streptavidin | / | 0.447 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.447 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.447 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2rtf | BTN | Streptavidin | / | 0.447 | |
| 2xvw | 9NR | Serum albumin | / | 0.447 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.447 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.447 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.447 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.447 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.447 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.447 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 4o7u | THF | Thymidylate synthase | / | 0.447 | |
| 4uy6 | SAH | Histidine N-alpha-methyltransferase | / | 0.447 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.447 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.447 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.446 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.446 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.446 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.446 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.446 | |
| 2izl | IMI | Streptavidin | / | 0.446 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.446 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.446 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.446 | |
| 3ry2 | BTN | Streptavidin | / | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.446 | |
| 4jyz | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 4lut | DCS | Alanine racemase | / | 0.446 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.446 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.446 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 1lgt | BP3 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.445 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.445 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.445 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.445 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.445 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.445 | |
| 4eak | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.445 | |
| 5agy | GTB | Tau class glutathione S-transferase | / | 0.445 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.444 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.444 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.444 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.444 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.444 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.444 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.444 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.444 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.444 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.444 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.444 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.444 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4jtr | IBP | Aldo-keto reductase family 1 member C2 | / | 0.444 | |
| 1lcw | SHM | Streptavidin | / | 0.443 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.443 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.443 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.443 | |
| 2ilu | NDP | Lactaldehyde dehydrogenase | 1.2.1.22 | 0.443 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.443 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.443 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.443 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.443 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.443 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.443 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.443 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.443 | |
| 4nbw | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.443 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.443 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.443 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.443 | |
| 1odj | GMP | Purine nucleoside phosphorylase | / | 0.442 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.442 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.442 | |
| 2ohj | FMN | Type A flavoprotein FprA | 1 | 0.442 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.442 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.442 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.442 | |
| 3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.442 | |
| 3v2u | ATP | Protein GAL3 | / | 0.442 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.442 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.442 | |
| 4gda | BTN | Streptavidin | / | 0.442 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.442 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.442 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.442 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.442 | |
| 4rxs | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.442 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.442 | |
| 1c7o | PPG | Hemolysin | / | 0.441 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.441 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.441 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.441 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.441 | |
| 2zb8 | IMN | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3e6e | DCS | Alanine racemase | / | 0.441 | |
| 3lkh | LT6 | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3qfr | FMN | NADPH--cytochrome P450 reductase | / | 0.441 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.441 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.441 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
| 4h7c | 10H | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.441 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.441 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.441 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.441 | |
| 1a27 | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1bzm | MZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.440 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.440 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2avi | BTN | Avidin | / | 0.440 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.440 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.440 | |
| 2glr | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.440 | |
| 2j40 | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.440 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.440 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.440 | |
| 2uuo | LK3 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.440 | |
| 3af1 | GDP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3fcj | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.440 | |
| 3mtw | M3R | Xaa-Pro dipeptidase, putative | / | 0.440 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.440 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.440 | |
| 3wag | TYD | Glycosyltransferase | / | 0.440 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.440 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.440 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.440 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.440 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.440 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.440 |