sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2p98 | YE7 | Methionine aminopeptidase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2p98 | YE7 | Methionine aminopeptidase | / | 1.000 | |
| 2q94 | A04 | Methionine aminopeptidase | / | 0.772 | |
| 2evm | FC2 | Methionine aminopeptidase | / | 0.750 | |
| 2q92 | B23 | Methionine aminopeptidase | / | 0.729 | |
| 2p99 | YE6 | Methionine aminopeptidase | / | 0.717 | |
| 3d27 | W29 | Methionine aminopeptidase | / | 0.703 | |
| 2evc | FC3 | Methionine aminopeptidase | / | 0.699 | |
| 1xnz | FCD | Methionine aminopeptidase | / | 0.680 | |
| 2q96 | A18 | Methionine aminopeptidase | / | 0.680 | |
| 2q93 | B21 | Methionine aminopeptidase | / | 0.673 | |
| 2gg2 | U12 | Methionine aminopeptidase | / | 0.668 | |
| 2ggb | U17 | Methionine aminopeptidase | / | 0.668 | |
| 2gg3 | U13 | Methionine aminopeptidase | / | 0.662 | |
| 3iu7 | FCD | Methionine aminopeptidase 2 | / | 0.661 | |
| 2gg8 | U15 | Methionine aminopeptidase | / | 0.649 | |
| 2gg0 | U11 | Methionine aminopeptidase | / | 0.644 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.643 | |
| 2g6p | HM2 | Methionine aminopeptidase 1 | / | 0.624 | |
| 4flk | Y10 | Methionine aminopeptidase 1 | / | 0.612 | |
| 3pke | Y10 | Methionine aminopeptidase 2 | / | 0.609 | |
| 4iks | TFD | Methionine aminopeptidase 1 | / | 0.609 | |
| 2gg9 | U16 | Methionine aminopeptidase | / | 0.608 | |
| 1c23 | MPH | Methionine aminopeptidase | / | 0.603 | |
| 4flj | Y08 | Methionine aminopeptidase 1 | / | 0.593 | |
| 2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.577 | |
| 3pkb | Y16 | Methionine aminopeptidase 2 | / | 0.573 | |
| 4hxx | 1AY | Methionine aminopeptidase 1 | / | 0.566 | |
| 3pka | Y02 | Methionine aminopeptidase 2 | / | 0.565 | |
| 3pkd | Y10 | Methionine aminopeptidase 2 | / | 0.563 | |
| 4fll | YZ6 | Methionine aminopeptidase 1 | / | 0.563 | |
| 4ikt | TFV | Methionine aminopeptidase 1 | / | 0.561 | |
| 3pkc | Y08 | Methionine aminopeptidase 2 | / | 0.547 | |
| 4iku | SHX | Methionine aminopeptidase 1 | / | 0.546 | |
| 4ikr | PVP | Methionine aminopeptidase 1 | / | 0.537 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.533 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.531 | |
| 4fli | Y16 | Methionine aminopeptidase 1 | / | 0.529 | |
| 2oaz | I96 | Methionine aminopeptidase 2 | / | 0.526 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.523 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.517 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.517 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.511 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.511 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.509 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.509 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.506 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.506 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.504 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.503 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.502 | |
| 2ga2 | A19 | Methionine aminopeptidase 2 | / | 0.501 | |
| 1qzy | TDE | Methionine aminopeptidase 2 | / | 0.499 | |
| 2pb1 | NFG | Glucan 1,3-beta-glucosidase | / | 0.499 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.498 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.497 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.497 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.497 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.496 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.496 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.495 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.495 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.495 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.495 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.495 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.493 | |
| 2jl1 | NAP | Triphenylmethane reductase | / | 0.492 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.492 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.492 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.492 | |
| 4drn | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.491 | |
| 4dh0 | MR8 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.490 | |
| 4nv1 | 4TG | Formyl transferase | / | 0.490 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.489 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.489 | |
| 3bv7 | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.489 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.489 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 1yum | NCN | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.488 | |
| 2ixk | TDO | dTDP-4-dehydrorhamnose 3,5-epimerase | 5.1.3.13 | 0.488 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.487 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.487 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.487 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.487 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.486 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.485 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.485 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.485 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.484 | |
| 2aot | 2PM | Histamine N-methyltransferase | 2.1.1.8 | 0.484 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.484 | |
| 4b7z | Q4Q | Acetylcholinesterase | 3.1.1.7 | 0.484 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.483 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.483 | |
| 4d6q | PD2 | Lysine-specific demethylase 4D | 1.14.11 | 0.483 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.482 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.481 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 2xuf | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.481 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.480 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.480 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.480 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.480 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.479 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.479 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.479 | |
| 1yw9 | A84 | Methionine aminopeptidase 2 | / | 0.479 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.479 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.479 | |
| 1fkg | SB3 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.478 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.478 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.478 | |
| 4kq6 | DLZ | 6,7-dimethyl-8-ribityllumazine synthase | / | 0.478 | |
| 1u65 | CP0 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.477 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.477 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.477 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.476 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.476 | |
| 4bb2 | STR | Corticosteroid-binding globulin | / | 0.476 | |
| 4q7f | 3D1 | Uncharacterized protein | / | 0.476 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.476 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.475 | |
| 2oz5 | 7XY | Uncharacterized protein | / | 0.475 | |
| 2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.475 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.475 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.474 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.474 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.473 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.473 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.473 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.473 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.473 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.473 | |
| 3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
| 4to2 | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.473 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.472 | |
| 2jf0 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.472 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.472 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.472 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.472 | |
| 5ah5 | LSS | Leucine--tRNA ligase | / | 0.472 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.471 | |
| 2a3b | CFF | Endochitinase B1 | 3.2.1.14 | 0.471 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.471 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 3t0i | SAH | Putative methyltransferase | / | 0.471 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.471 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.471 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.470 | |
| 2ipi | AKY | Aclacinomycin-N/aclacinomycin-A oxidase | / | 0.470 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.470 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.470 | |
| 3egk | M18 | Prothrombin | 3.4.21.5 | 0.470 | |
| 3mj4 | URM | UDP-galactopyranose mutase | / | 0.470 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.470 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.469 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
| 1v08 | NTZ | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic | 3.2.1.182 | 0.469 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.469 | |
| 3uzz | TES | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.469 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.469 | |
| 4rxr | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.469 | |
| 2jgb | MGT | Eukaryotic translation initiation factor 4E type 2 | / | 0.468 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.468 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.468 | |
| 1fap | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.467 | |
| 1fap | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.467 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.467 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.467 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.467 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.467 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.467 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.467 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.467 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.467 | |
| 4wlj | IK2 | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.467 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.466 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.466 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.466 | |
| 1ni1 | 2C5 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.466 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.466 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.466 | |
| 4b11 | 7I1 | Glycylpeptide N-tetradecanoyltransferase | / | 0.466 | |
| 4b64 | NAP | L-ornithine N(5)-monooxygenase | / | 0.466 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.466 | |
| 1fkj | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.465 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 2v9c | MRE | FMN-dependent NADH-azoreductase 1 | / | 0.465 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.465 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3q7j | FBO | Tricorn protease-interacting factor F3 | 3.4.11 | 0.465 | |
| 4bfs | ZVS | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.465 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.465 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.465 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.464 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 2xjc | 5GP | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.464 | |
| 2xje | U5P | Cytosolic purine 5'-nucleotidase | 3.1.3.5 | 0.464 | |
| 3h7r | NAP | Aldo-keto reductase family 4 member C8 | / | 0.464 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 3vf2 | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.464 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.464 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.464 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.464 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.464 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.463 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.463 | |
| 3fsj | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.463 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.463 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.463 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.463 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.462 | |
| 2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.462 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.462 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.462 | |
| 4gv2 | 5ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.462 | |
| 4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.462 | |
| 4to5 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.462 | |
| 1c9h | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1B | 5.2.1.8 | 0.461 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.461 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.461 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.461 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.461 | |
| 1e2n | RCA | Thymidine kinase | / | 0.460 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 2bxo | OPB | Serum albumin | / | 0.460 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.460 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.460 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.460 | |
| 3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.460 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.460 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.460 | |
| 5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.460 | |
| 1i9c | 5AD | Glutamate mutase epsilon subunit | / | 0.459 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.459 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.459 | |
| 2ct8 | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.459 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.459 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.459 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.458 | |
| 1pr4 | MTP | Purine nucleoside phosphorylase DeoD-type | / | 0.458 | |
| 2aba | STR | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.458 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4j4n | D44 | Peptidylprolyl isomerase | / | 0.458 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.458 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.458 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.458 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.457 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.457 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.457 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.457 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.457 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.457 | |
| 4eph | 0RK | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.457 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.457 | |
| 4qt3 | RAP | Peptidylprolyl isomerase | / | 0.457 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.456 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.456 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.456 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3b4p | 3B4 | Phenazine biosynthesis protein A/B | / | 0.456 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.456 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.456 | |
| 3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.456 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.456 | |
| 4m0c | FMN | FMN-dependent NADH-azoreductase 1 | / | 0.456 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.455 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.455 | |
| 3bl7 | DD1 | m7GpppX diphosphatase | 3.6.1.59 | 0.455 | |
| 3caq | NDP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3dr7 | GPD | GDP-perosamine synthase | / | 0.455 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.455 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.455 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.455 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.455 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.454 | |
| 2g0b | NLT | Long-chain N-acyl amino acid synthase | / | 0.454 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.454 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.454 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.454 | |
| 4c13 | UML | UDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase | / | 0.454 | |
| 4lcn | GNG | Cytidine and deoxycytidylate deaminase zinc-binding region | / | 0.454 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.453 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.453 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.453 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.453 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.453 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.453 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 4nv1 | TYD | Formyl transferase | / | 0.453 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.453 | |
| 4rxp | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.453 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 1fkl | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.452 | |
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.452 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.452 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.452 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.452 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.452 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.452 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.452 | |
| 4qg0 | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.452 | |
| 5c48 | URM | Histo-blood group ABO system transferase | / | 0.452 | |
| 5cxv | 0HK | Muscarinic acetylcholine receptor M1 | / | 0.452 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.451 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 2zsb | ADP | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 3c1o | NAP | Eugenol synthase | / | 0.451 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 3zj6 | VM2 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.451 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.451 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.451 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.450 | |
| 1nqv | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.450 | |
| 1o23 | UPG | Beta-1,4-galactosyltransferase 1 | / | 0.450 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 1xh8 | R55 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.450 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.450 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.450 | |
| 2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.450 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.450 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.450 | |
| 4a16 | H34 | Acetylcholinesterase | 3.1.1.7 | 0.450 | |
| 4dlc | UMP | Deoxyuridine triphosphatase, putative | / | 0.450 | |
| 5cho | FAD | Flavin reductase | / | 0.450 | |
| 1fkd | 818 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 1h66 | RH1 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.449 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.449 | |
| 1nj5 | P5A | Proline--tRNA ligase | / | 0.449 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.449 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.449 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.449 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.449 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.449 | |
| 2v5u | FMN | Flavodoxin | / | 0.449 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3e4v | FMN | Uncharacterized protein | / | 0.449 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.449 | |
| 3hii | PNT | Amiloride-sensitive amine oxidase [copper-containing] | / | 0.449 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.449 | |
| 4b66 | NAP | L-ornithine N(5)-monooxygenase | / | 0.449 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.449 | |
| 4j7g | TRH | PCZA361.3 | / | 0.449 | |
| 4zwe | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.449 | |
| 1bkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.448 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.448 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.448 | |
| 2e94 | 364 | Geranylgeranyl pyrophosphate synthase | / | 0.448 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.448 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.448 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.448 | |
| 3hxc | BD6 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.448 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.448 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4drh | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.448 | |
| 4drh | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.448 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.448 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.448 | |
| 4qg1 | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.448 | |
| 5a8a | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.448 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.448 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.447 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.447 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.447 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.447 | |
| 1s4p | GDP | Glycolipid 2-alpha-mannosyltransferase | / | 0.447 | |
| 2hp2 | KE4 | Glutamate-1-semialdehyde 2,1-aminomutase | 5.4.3.8 | 0.447 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.447 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.447 | |
| 3int | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.447 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.447 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.447 | |
| 3v2u | ATP | Protein GAL3 | / | 0.447 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.447 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4bup | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.447 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.447 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.447 | |
| 4wdf | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 5c80 | URI | Uridine phosphorylase | / | 0.447 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.446 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.446 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 1s1r | NAP | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 1vfs | DCS | Alanine racemase | / | 0.446 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.446 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.446 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.446 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2rd6 | 78P | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 2xys | SY9 | Soluble acetylcholine receptor | / | 0.446 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3hat | GLY_VAL_ARG_RNG | Prothrombin | 3.4.21.5 | 0.446 | |
| 3irh | DTP | HD domain protein | / | 0.446 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.446 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.446 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.446 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.446 | |
| 1mu8 | CDB | Prothrombin | 3.4.21.5 | 0.445 | |
| 1n95 | FTH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 1yro | GDU | Beta-1,4-galactosyltransferase 1 | / | 0.445 | |
| 2h21 | SAM | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.445 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.445 | |
| 2z4w | 749 | Geranylgeranyl pyrophosphate synthase | / | 0.445 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.445 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.445 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.445 | |
| 3g5i | DNB | Pyrimidine-specific ribonucleoside hydrolase RihA | / | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.445 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.445 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.445 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.445 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.445 | |
| 4to4 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.445 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.445 | |
| 5d5a | CAU | Beta-2 adrenergic receptor | / | 0.445 | |
| 1acj | THA | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.444 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.444 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.444 | |
| 4b63 | FAD | L-ornithine N(5)-monooxygenase | / | 0.444 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.444 | |
| 1ij8 | BNI | Avidin | / | 0.443 | |
| 1jmg | UMP | Thymidylate synthase | / | 0.443 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.443 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.443 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.443 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.443 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2xwe | AMF | Glucosylceramidase | 3.2.1.45 | 0.443 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.443 | |
| 3fx6 | BPX | Carboxypeptidase A1 | 3.4.17.1 | 0.443 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.443 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.443 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.443 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4diq | PD2 | Ribosomal oxygenase 1 | / | 0.443 | |
| 4e31 | JHZ | Methyltransferase | / | 0.443 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4kxj | P34 | Nucleoprotein | / | 0.443 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.443 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 1c7o | PPG | Hemolysin | / | 0.442 | |
| 1je1 | GMP | Purine nucleoside phosphorylase | / | 0.442 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.442 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 2fke | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.442 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.442 | |
| 2v57 | PRL | TetR family transcriptional regulator | / | 0.442 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.442 | |
| 3kkz | SAM | Uncharacterized protein | / | 0.442 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.442 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.442 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.442 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.442 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.442 | |
| 4hcy | 0YN | Transketolase | / | 0.442 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4jfi | 1KT | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.442 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.442 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.442 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.441 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.441 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.441 | |
| 3b8x | G4M | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.441 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.441 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3fvu | IAC | Kynurenine--oxoglutarate transaminase 1 | 2.6.1.7 | 0.441 | |
| 3lut | NAP | Voltage-gated potassium channel subunit beta-2 | / | 0.441 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.441 | |
| 3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.441 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.441 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.441 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4lut | DCS | Alanine racemase | / | 0.441 | |
| 4nv0 | MG7 | 7-methylguanosine phosphate-specific 5'-nucleotidase | / | 0.441 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.441 | |
| 5ief | NBV | Neutral alpha-glucosidase AB | 3.2.1.84 | 0.441 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.440 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.440 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.440 | |
| 2a2x | NA9 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2c6c | 24I | Glutamate carboxypeptidase 2 | 3.4.17.21 | 0.440 | |
| 2cda | NAP | Glucose 1-dehydrogenase | / | 0.440 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.440 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2hej | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.440 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.440 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.440 | |
| 3vew | ADP | nebramycin 5' synthase | 6.1.2.2 | 0.440 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 4g8j | THM | Uridine phosphorylase | / | 0.440 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.440 | |
| 4rel | KMP | Glycosyltransferase | / | 0.440 |