sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 1j8q | FMN | Flavodoxin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 1j8q | FMN | Flavodoxin | / | 1.000 | |
| 2fx2 | FMN | Flavodoxin | / | 0.646 | |
| 1fx1 | FMN | Flavodoxin | / | 0.636 | |
| 1wsb | FMN | Flavodoxin | / | 0.629 | |
| 1akw | FMN | Flavodoxin | / | 0.606 | |
| 1azl | FMN | Flavodoxin | / | 0.605 | |
| 1aku | FMN | Flavodoxin | / | 0.603 | |
| 5fx2 | FMN | Flavodoxin | / | 0.593 | |
| 1j9g | FMN | Flavodoxin | / | 0.583 | |
| 1akr | FMN | Flavodoxin | / | 0.581 | |
| 3f6s | FMN | Flavodoxin | / | 0.562 | |
| 5tgz | FMN | Cannabinoid receptor 1 | / | 0.555 | |
| 4fx2 | FMN | Flavodoxin | / | 0.547 | |
| 1xyv | FMN | Flavodoxin | / | 0.538 | |
| 4y7c | FMN | NADPH--cytochrome P450 reductase | / | 0.531 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.530 | |
| 3f6r | FMN | Flavodoxin | / | 0.526 | |
| 5xra | FMN | Cannabinoid receptor 1 | / | 0.525 | |
| 3kaq | FMN | Flavodoxin | / | 0.524 | |
| 3kap | FMN | Flavodoxin | / | 0.515 | |
| 3f90 | FMN | Flavodoxin | / | 0.511 | |
| 1c7f | FMN | Flavodoxin | / | 0.508 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.508 | |
| 4oxx | FMN | Cindoxin | / | 0.508 | |
| 1ahn | FMN | Flavodoxin 1 | / | 0.507 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.507 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.500 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.499 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.498 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.498 | |
| 2v5u | FMN | Flavodoxin | / | 0.497 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.497 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.497 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.496 | |
| 3hr4 | FMN | Nitric oxide synthase, inducible | 1.14.13.39 | 0.494 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.493 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.492 | |
| 1bu5 | RBF | Flavodoxin | / | 0.491 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.491 | |
| 2mok | FMN | Flavodoxin 1 | / | 0.491 | |
| 1vot | HUP | Acetylcholinesterase | 3.1.1.7 | 0.488 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.488 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.488 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.487 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.487 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.487 | |
| 1ykg | FMN | Sulfite reductase [NADPH] flavoprotein alpha-component | / | 0.486 | |
| 3nz2 | ACO | Hexapeptide-repeat containing-acetyltransferase | / | 0.486 | |
| 3w2f | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.486 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.485 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.485 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.485 | |
| 1xyy | FMN | Flavodoxin | / | 0.484 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.484 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.484 | |
| 4a31 | 2CB | Glycylpeptide N-tetradecanoyltransferase | / | 0.484 | |
| 1czn | FMN | Flavodoxin | / | 0.483 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.483 | |
| 3i6q | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.483 | |
| 3v2u | ATP | Protein GAL3 | / | 0.483 | |
| 4x9d | U5P | Uncharacterized protein MJ1435 | / | 0.483 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.482 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.482 | |
| 2fcr | FMN | Flavodoxin | / | 0.481 | |
| 2wnb | C5P | CMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 1 | 2.4.99.4 | 0.481 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.481 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.480 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.480 | |
| 3esy | FMN | Flavodoxin | / | 0.480 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.480 | |
| 5xr8 | FMN | Cannabinoid receptor 1 | / | 0.480 | |
| 2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.479 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.479 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.479 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.478 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.478 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.477 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.477 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.476 | |
| 4u14 | 0HK | Muscarinic acetylcholine receptor M3 | / | 0.476 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.475 | |
| 1ygk | RRC | Pyridoxal kinase | 2.7.1.35 | 0.475 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.475 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.475 | |
| 4epq | 0RR | Poly(ADP-ribose) glycohydrolase | / | 0.475 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 1j9z | FMN | NADPH--cytochrome P450 reductase | / | 0.474 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.474 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 2ii6 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.474 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.474 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.474 | |
| 3fpk | FAD | Ferredoxin-NADP reductase | / | 0.474 | |
| 4gv7 | MEW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.474 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.474 | |
| 1mxf | MTX | Putative pteridine reductase 2 | / | 0.473 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.473 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.473 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.473 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.473 | |
| 4b1h | AR6 | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.473 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.473 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.473 | |
| 2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.472 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.472 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.472 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.471 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.471 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.471 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.471 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.470 | |
| 3arv | SAU | Chitinase A | / | 0.470 | |
| 3ojw | FMN | NADPH--cytochrome P450 reductase | / | 0.470 | |
| 3ukf | GDU | UDP-galactopyranose mutase | / | 0.470 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.470 | |
| 1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.469 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.469 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.469 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.469 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.468 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.468 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3sf6 | FDA | Glutaryl-CoA dehydrogenase | / | 0.468 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 4gi5 | FAD | Putative NAD(P)H dehydrogenase (Quinone) | / | 0.468 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.467 | |
| 1i7p | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.467 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.467 | |
| 3ojx | FAD | NADPH--cytochrome P450 reductase | / | 0.467 | |
| 4b2g | V1N | Uncharacterized protein | / | 0.467 | |
| 4kp7 | 1UQ | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.467 | |
| 4nv1 | 0FX | Formyl transferase | / | 0.467 | |
| 1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.466 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.466 | |
| 2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.466 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.466 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.466 | |
| 3gjw | GJW | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.466 | |
| 4bmp | FMN | Protein NrdI | / | 0.466 | |
| 4fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.466 | |
| 4fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.466 | |
| 1ofv | FMN | Flavodoxin | / | 0.465 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.465 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.465 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.465 | |
| 2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.465 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.465 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.465 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.465 | |
| 4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.465 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.465 | |
| 1h69 | ARH | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.464 | |
| 1vgq | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.464 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.464 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.464 | |
| 2pbw | DOQ | Glutamate receptor ionotropic, kainate 1 | / | 0.464 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.464 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.464 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.463 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.463 | |
| 1ygj | RMC | Pyridoxal kinase | 2.7.1.35 | 0.463 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.463 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.463 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.463 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.463 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.463 | |
| 1h42 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.462 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.462 | |
| 2b5o | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.462 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3ai0 | PNW | Beta-glucosidase | / | 0.462 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.462 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.462 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.462 | |
| 4zzi | 1NS | NAD-dependent protein deacetylase sirtuin-1 | 3.5.1 | 0.462 | |
| 1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.461 | |
| 1ulb | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.461 | |
| 1w19 | T5P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.461 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.461 | |
| 2clm | F6F | Tryptophan synthase alpha chain | / | 0.461 | |
| 2fhj | H4Z | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.461 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.461 | |
| 2xi4 | AFT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 3d4b | DZD | NAD-dependent protein deacetylase | / | 0.461 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.461 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.461 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.461 | |
| 5dp2 | NAP | CurF | / | 0.461 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.461 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.460 | |
| 2wwj | Y28 | Lysine-specific demethylase 4A | / | 0.460 | |
| 2xug | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.460 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.460 | |
| 4b65 | NDP | L-ornithine N(5)-monooxygenase | / | 0.460 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.460 | |
| 4d96 | 5PA | D-cysteine desulfhydrase | / | 0.460 | |
| 4eqr | COA | Coenzyme A disulfide reductase | / | 0.460 | |
| 4rpg | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.460 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1pwy | AC2 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.459 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.459 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.459 | |
| 3nub | UD0 | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.459 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.459 | |
| 4lxl | PD2 | Lysine-specific demethylase 4B | 1.14.11 | 0.459 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.459 | |
| 1ix1 | BB2 | Peptide deformylase | / | 0.458 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.458 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.458 | |
| 1ypl | RA8 | Prothrombin | 3.4.21.5 | 0.458 | |
| 1yqz | COA | Coenzyme A disulfide reductase | / | 0.458 | |
| 1zdw | FLV | Prenyltransferase | / | 0.458 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.458 | |
| 2cmf | F11 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 2gms | P0P | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.458 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.458 | |
| 3mhp | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.458 | |
| 3p0e | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.458 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.458 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.458 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.458 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.458 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4yfy | 0FX | VioF | / | 0.458 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.457 | |
| 2ejz | SAH | Diphthine synthase | / | 0.457 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 2vet | UMP | Thymidylate synthase | / | 0.457 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.457 | |
| 2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.457 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 3klb | FMN | Uncharacterized protein | / | 0.457 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.457 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.457 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.457 | |
| 4na4 | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.457 | |
| 4nie | NBH | Nuclear receptor ROR-gamma | / | 0.457 | |
| 5fd8 | A5A | Putative carboxypeptidase yocD | / | 0.457 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 1fml | RTL | Retinol dehydratase | / | 0.456 | |
| 2ha6 | SCK | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.456 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.455 | |
| 2gmu | PDG | Putative pyridoxamine 5-phosphate-dependent dehydrase | / | 0.455 | |
| 2pj4 | 414 | Carboxypeptidase B | / | 0.455 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.455 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.455 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4ge9 | 0L0 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.455 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.455 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.455 | |
| 4tvj | 09L | Poly [ADP-ribose] polymerase 2 | 2.4.2.30 | 0.455 | |
| 1fdr | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.454 | |
| 1u71 | MXA | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1w76 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.454 | |
| 2bt4 | CA2 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.454 | |
| 2jgs | BTN | Avidin | / | 0.454 | |
| 2o3u | NGD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.454 | |
| 2ohi | FMN | Type A flavoprotein FprA | 1 | 0.454 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.454 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.453 | |
| 1vf3 | GDN | Glutathione S-transferase 3 | 2.5.1.18 | 0.453 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.453 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.453 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.453 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.453 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.453 | |
| 3udn | 09B | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 4b1e | 6T6 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.453 | |
| 4b68 | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4bis | 8HQ | Lysine-specific demethylase 4A | 1.14.11 | 0.453 | |
| 4ca8 | 3ES | Angiotensin-converting enzyme | 3.4.15.1 | 0.453 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.453 | |
| 4jq3 | NAP | Aldo-keto reductase family 1 member C2 | / | 0.453 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.453 | |
| 4tti | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.453 | |
| 4y17 | LAE | Transcriptional regulator of ftsQAZ gene cluster | / | 0.453 | |
| 1so2 | 666 | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.452 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.452 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.452 | |
| 1z71 | L17 | Prothrombin | 3.4.21.5 | 0.452 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.452 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.452 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.452 | |
| 3dzj | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.452 | |
| 3go4 | SAH | Uncharacterized protein | / | 0.452 | |
| 3u8l | 09Q | Acetylcholine-binding protein | / | 0.452 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.452 | |
| 3zc3 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.452 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.452 | |
| 4jt9 | 1NS | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.452 | |
| 4l1f | COS | Acyl-CoA dehydrogenase domain protein | / | 0.452 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.451 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.451 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
| 1tco | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 1tco | FK5 | Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform | 3.1.3.16 | 0.451 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.451 | |
| 2dxi | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.451 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.451 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.451 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.451 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.451 | |
| 3voi | RCB | Glucanase | / | 0.451 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.451 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.451 | |
| 4jt8 | 1NR | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.451 | |
| 1a9p | 9DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1b8o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.450 | |
| 1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.450 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1nj6 | A5A | Proline--tRNA ligase | / | 0.450 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.450 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.450 | |
| 2r8p | T6F | Transketolase 1 | / | 0.450 | |
| 2vd7 | PD2 | Lysine-specific demethylase 4A | 1.14.11 | 0.450 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.450 | |
| 3euf | BAU | Uridine phosphorylase 1 | / | 0.450 | |
| 3f8s | PF2 | Dipeptidyl peptidase 4 | / | 0.450 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 4bv9 | NDP | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.450 | |
| 4h0v | NAD | Iota toxin component Ia | / | 0.450 | |
| 4paa | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.450 | |
| 4pab | THG | Dimethylglycine dehydrogenase, mitochondrial | 1.5.8.4 | 0.450 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA2 | 3.6.3 | 0.450 | |
| 4zir | ANP | Energy-coupling factor transporter ATP-binding protein EcfA1 | / | 0.450 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.450 | |
| 1a9s | NOS | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.449 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.449 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.449 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.449 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.449 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.449 | |
| 3jqr | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.449 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.449 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.449 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.449 | |
| 4a2z | VIQ | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.449 | |
| 4e2y | JHZ | Methyltransferase | / | 0.449 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.449 | |
| 4hh4 | SAH | CcbJ | / | 0.449 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.449 | |
| 4kxj | P34 | Nucleoprotein | / | 0.449 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 1amo | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 1efy | BZC | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.448 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.448 | |
| 1m4i | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.448 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 1r5h | AO2 | Methionine aminopeptidase 2 | / | 0.448 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.448 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 2xb9 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.448 | |
| 2y05 | RAL | Prostaglandin reductase 1 | / | 0.448 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3gb4 | D3M | DdmC | / | 0.448 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 3qft | FAD | NADPH--cytochrome P450 reductase | / | 0.448 | |
| 3uel | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.448 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.448 | |
| 4e2z | JHZ | Methyltransferase | / | 0.448 | |
| 4k37 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.448 | |
| 1b8n | IMG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.447 | |
| 1nzy | BCA | 4-chlorobenzoyl coenzyme A dehalogenase | 3.8.1.7 | 0.447 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.447 | |
| 1pl1 | ABY | Glutathione S-transferase A1 | 2.5.1.18 | 0.447 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1w4l | GL8 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 2aov | C2M | Histamine N-methyltransferase | 2.1.1.8 | 0.447 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.447 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.447 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.447 | |
| 2xda | JPS | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.447 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.447 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.447 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.447 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.447 | |
| 4gv0 | 8ME | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.447 | |
| 4jsr | 1NQ | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.447 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.447 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.447 | |
| 4rvf | TYD | D-mycarose 3-C-methyltransferase | / | 0.447 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.446 | |
| 1k4m | NAD | Nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.446 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.446 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1rpw | DID | HTH-type transcriptional regulator QacR | / | 0.446 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 2npi | ATP | mRNA cleavage and polyadenylation factor CLP1 | / | 0.446 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.446 | |
| 3c35 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.446 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.446 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3iu9 | T07 | Methionine aminopeptidase 2 | / | 0.446 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.446 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.446 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.446 | |
| 4e32 | DWN | Methyltransferase | / | 0.446 | |
| 4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.446 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.446 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.446 | |
| 1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.445 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.445 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.445 | |
| 1gg5 | E09 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
| 1xp8 | AGS | Protein RecA | / | 0.445 | |
| 1zgv | 501 | Prothrombin | 3.4.21.5 | 0.445 | |
| 2aj4 | ANP | Galactokinase | 2.7.1.6 | 0.445 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.445 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 2hek | GDP | Uncharacterized protein | / | 0.445 | |
| 2xve | FAD | Putative flavin-containing monooxygenase | / | 0.445 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3gr8 | FMN | NADPH dehydrogenase | / | 0.445 | |
| 3ho9 | N3A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 3ikt | NAD | Redox-sensing transcriptional repressor Rex | / | 0.445 | |
| 3tfy | COA | N-alpha-acetyltransferase 50 | 2.3.1 | 0.445 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.445 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.445 | |
| 3zj7 | C1K | Strictosidine-O-beta-D-glucosidase | 3.2.1.105 | 0.445 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.445 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.445 | |
| 4glx | 0XS | DNA ligase | 6.5.1.2 | 0.445 | |
| 4gts | 7TP | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.445 | |
| 4h6p | FMN | Chromate reductase | / | 0.445 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.445 | |
| 4qtn | NNR | Nicotinamide riboside transporter PnuC | / | 0.445 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.445 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.445 | |
| 4xwt | U5P | Ribonuclease J | / | 0.445 | |
| 1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.444 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.444 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.444 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.444 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.444 | |
| 1w35 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.444 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.444 | |
| 2ckm | AA7 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 2cv2 | GSU | Glutamate--tRNA ligase | 6.1.1.17 | 0.444 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 3h2s | NDP | Putative NADH-flavin reductase | / | 0.444 | |
| 3l3l | L3L | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.444 | |
| 3lz6 | A0D | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.444 | |
| 3ndj | JHZ | Methyltransferase | / | 0.444 | |
| 3nu0 | 3TU | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3sig | AR6 | Uncharacterized protein | / | 0.444 | |
| 3uzx | AOM | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 4b1j | A1R | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.444 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4l5a | TBN | S-methyl-5'-thioadenosine phosphorylase | / | 0.444 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.444 | |
| 1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.443 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.443 | |
| 1mrk | FMC | Ribosome-inactivating protein alpha-trichosanthin | 3.2.2.22 | 0.443 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.443 | |
| 1swe | BTN | Streptavidin | / | 0.443 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
| 1ut6 | A8N | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.443 | |
| 2bgs | NDP | Aldose reductase | 1.1.1.21 | 0.443 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.443 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.443 | |
| 2msd | GNP | MHC class I alpha chain | / | 0.443 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.443 | |
| 2xq0 | BES | Leukotriene A-4 hydrolase homolog | 3.3.2.6 | 0.443 | |
| 2xuj | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.443 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.443 | |
| 3lq2 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.443 | |
| 3nn6 | HNK | 6-hydroxy-L-nicotine oxidase | / | 0.443 | |
| 3px3 | T3Q | dTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase | 2.1.1.235 | 0.443 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.443 | |
| 3zhu | TD8 | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.443 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.443 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.443 | |
| 4ffw | 715 | Dipeptidyl peptidase 4 | / | 0.443 | |
| 4gd9 | BTN | Streptavidin | / | 0.443 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.443 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.443 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.442 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.442 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1ycg | FMN | Nitric oxide reductase | 1 | 0.442 | |
| 2fap | RAD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.442 | |
| 2fap | RAD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.442 | |
| 2fb3 | 5AD | GTP 3',8-cyclase | 4.1.99.18 | 0.442 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.442 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.442 | |
| 2gyu | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.442 | |
| 2r6h | FAD | Na(+)-translocating NADH-quinone reductase subunit F | / | 0.442 | |
| 2re8 | GSU | Glutamine--tRNA ligase | 6.1.1.18 | 0.442 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.442 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.442 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.442 | |
| 2zru | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.442 | |
| 3abx | RCB | Glucanase | / | 0.442 | |
| 3b4y | F42 | F420-dependent glucose-6-phosphate dehydrogenase | / | 0.442 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.442 | |
| 3ox4 | NAD | Alcohol dehydrogenase 2 | 1.1.1.1 | 0.442 | |
| 3pn1 | IVH | DNA ligase | / | 0.442 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.442 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.442 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 4j1e | 1HM | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 5fe1 | 12Q | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.442 | |
| 1aiq | CB3 | Thymidylate synthase | / | 0.441 | |
| 1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.441 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.441 | |
| 1r2j | FAD | FkbI | / | 0.441 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.441 | |
| 1ycf | FMN | Nitric oxide reductase | 1 | 0.441 | |
| 2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.441 | |
| 2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.441 | |
| 2get | COK | Pantothenate kinase | 2.7.1.33 | 0.441 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.441 | |
| 2iod | MYC | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.441 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.441 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2xvh | NAP | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3ens | ENS | Coagulation factor X | 3.4.21.6 | 0.441 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.441 | |
| 4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.441 | |
| 4std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.440 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1bx1 | FAD | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.440 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.440 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.440 | |
| 1lke | DOG | Bilin-binding protein | / | 0.440 | |
| 1ni1 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 1pr1 | FMB | Purine nucleoside phosphorylase DeoD-type | / | 0.440 | |
| 1ri4 | SAM | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.440 | |
| 1zgc | A2E | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.440 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.440 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.440 | |
| 2iu8 | UD1 | UDP-3-O-acylglucosamine N-acyltransferase | 2.3.1 | 0.440 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.440 | |
| 2pia | FMN | Phthalate dioxygenase reductase | / | 0.440 | |
| 2q0l | NAP | Thioredoxin reductase | 1.8.1.9 | 0.440 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3i6i | NDP | Putative leucoanthocyanidin reductase 1 | / | 0.440 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.440 | |
| 3nx2 | FER | Ferulic acid decarboxylase | / | 0.440 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.440 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4g8b | HL6 | Alpha/beta hydrolase fold protein | / | 0.440 | |
| 4jxr | ACO | Acetyltransferase | / | 0.440 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.440 | |
| 4r5w | XAV | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.440 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.440 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.440 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.440 | |
| 4u16 | 3C0 | Muscarinic acetylcholine receptor M3 | / | 0.440 |