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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Interaction pattern similarity measured by Grim
You can zoom onto the graph by using the mouse to make a selection

Binding Modes are compared using Grim.
For more information, please see the following publication: Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65


Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3f8p NAD NADH oxidase/thioredoxin reductase

Complex with similar interaction patterns:

PDB ID HET Uniprot Name EC Number Binding Mode
Similarity
Align
3f8p NADNADH oxidase/thioredoxin reductase / 0.831
3f8d FADNADH oxidase/thioredoxin reductase / 0.813
3f8r NAPNADH oxidase/thioredoxin reductase / 0.799
3lzw FADFerredoxin--NADP reductase 2 1.18.1.2 0.756
2q7v FADThioredoxin reductase / 0.753
1bxd ANPOsmolarity sensor protein EnvZ 2.7.13.3 0.744
1c4y IH3Prothrombin 3.4.21.5 0.744
1crb RTLRetinol-binding protein 1 / 0.744
1d3d BZTProthrombin 3.4.21.5 0.744
1diu BDMDihydrofolate reductase 1.5.1.3 0.744
1e3k R18Progesterone receptor / 0.744
1eh4 IC1Casein kinase I homolog 1 2.7.11.1 0.744
1ezv SMACytochrome b / 0.744
1f0q EMOCasein kinase II subunit alpha 2.7.11.1 0.744
1g9c BABBotulinum neurotoxin type B 3.4.24.69 0.744
1h0w 207Cyclin-dependent kinase 2 2.7.11.22 0.744
1hk5 T44Serum albumin / 0.744
1hni AAAGag-Pol polyprotein 2.7.7.49 0.744
1hnv TBOGag-Pol polyprotein 2.7.7.49 0.744
1hqu HBYGag-Pol polyprotein 2.7.7.49 0.744
1hrv SDZGenome polyprotein / 0.744
1i05 LTLMajor urinary protein 6 / 0.744
1i7g CPQPeroxisome proliferator-activated receptor alpha / 0.744
1i9m INWCarbonic anhydrase 2 4.2.1.1 0.744
1ikv EFZGag-Pol polyprotein 2.7.7.49 0.744
1iky MSDGag-Pol polyprotein 2.7.7.49 0.744
1jla TNKGag-Pol polyprotein 2.7.7.49 0.744
1jx0 DFVChalcone--flavonone isomerase 1 5.5.1.6 0.744
1kgj FL8Transthyretin / 0.744
1kkq 471Peroxisome proliferator-activated receptor alpha / 0.744
1kqw RTLCellular retinol-binding protein type II / 0.744
1kzu RG1Light-harvesting protein B-800/850 alpha chain / 0.744
1kzu RG1Light-harvesting protein B-800/850 beta chain / 0.744
1m9t INENitric oxide synthase, inducible 1.14.13.39 0.744
1n83 CLRNuclear receptor ROR-alpha / 0.744
1odc A8BAcetylcholinesterase 3.1.1.7 0.744
1pj6 FOLDimethylglycine oxidase 1.5.3.10 0.744
1pqc 444Oxysterols receptor LXR-beta / 0.744
1q20 PLOSulfotransferase family cytosolic 2B member 1 2.8.2.2 0.744
1qiw DPDCalmodulin / 0.744
1qjg EQUSteroid Delta-isomerase 5.3.3.1 0.744
1rev TB9Gag-Pol polyprotein 2.7.7.49 0.744
1rpw DIDHTH-type transcriptional regulator QacR / 0.744
1rt2 TNKGag-Pol polyprotein 2.7.7.49 0.744
1rt4 UC1Gag-Pol polyprotein 2.7.7.49 0.744
1rti HEFGag-Pol polyprotein 2.7.7.49 0.744
1s1t UC1Gag-Pol polyprotein 2.7.7.49 0.744
1sej F89Bifunctional dihydrofolate reductase-thymidylate synthase / 0.744
1snu STUTyrosine-protein kinase ITK/TSK 2.7.10.2 0.744
1suo CPZCytochrome P450 2B4 1.14.14.1 0.744
1tl3 H20Gag-Pol polyprotein 2.7.7.49 0.744
1tvr TB9Gag-Pol polyprotein 2.7.7.49 0.744
1uyk PUXHeat shock protein HSP 90-alpha / 0.744
1vru AAPGag-Pol polyprotein 2.7.7.49 0.744
1vzd CB3Thymidylate synthase / 0.744
1w6j R71Lanosterol synthase 5.4.99.7 0.744
1w6r GNTAcetylcholinesterase 3.1.1.7 0.744
1w76 GNTAcetylcholinesterase 3.1.1.7 0.744
1wxy FRKAdenosine deaminase 3.5.4.4 0.744
1xk9 P34Exotoxin A 2.4.2.36 0.744
1xws BI1Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
1yi4 ADNSerine/threonine-protein kinase pim-1 2.7.11.1 0.744
1ysw 43BApoptosis regulator Bcl-2 / 0.744
1z1f STLResveratrol synthase / 0.744
1zhw HC2Oxysterol-binding protein homolog 4 / 0.744
1zhy CLROxysterol-binding protein homolog 4 / 0.744
1zz1 SHHHistone deacetylase-like amidohydrolase 3.5.1 0.744
2a8g GNGAvidin / 0.744
2agv BHQSarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
2aid THKGag-Pol polyprotein 3.4.23.16 0.744
2aot 2PMHistamine N-methyltransferase 2.1.1.8 0.744
2aov C2MHistamine N-methyltransferase 2.1.1.8 0.744
2b00 GCHPhospholipase A2, major isoenzyme 3.1.1.4 0.744
2b5j 3ACGag-Pol polyprotein 2.7.7.49 0.744
2ban 357Gag-Pol polyprotein 2.7.7.49 0.744
2bfm TOPPteridine reductase 1 1.5.1.33 0.744
2bil BI1Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
2bjf DXCCholoylglycine hydrolase 3.5.1.24 0.744
2c7x NRBCytochrome P450 monooxygenase PikC / 0.744
2ckm AA7Acetylcholinesterase 3.1.1.7 0.744
2fhj H4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase 2.3.1.101 0.744
2fhk MFNFormylmethanofuran--tetrahydromethanopterin formyltransferase 2.3.1.101 0.744
2g44 T3OEstrogen receptor / 0.744
2gm1 2AZKinesin-like protein KIF11 / 0.744
2gz8 F3FOrf1a polyprotein / 0.744
2hnz PC0Gag-Pol polyprotein 2.7.7.49 0.744
2hz4 4STTyrosine-protein kinase ABL1 2.7.10.2 0.744
2i80 G1LD-alanine--D-alanine ligase / 0.744
2ibz SMACytochrome b / 0.744
2ic3 HBYGag-Pol polyprotein 2.7.7.49 0.744
2j0k 4STFocal adhesion kinase 1 2.7.10.2 0.744
2j2i LY4Serine/threonine-protein kinase pim-1 2.7.11.1 0.744
2kot ANWProtein S100-A13 / 0.744
2o21 43BApoptosis regulator Bcl-2 / 0.744
2ocf ESTEstrogen receptor / 0.744
2ohv NHLGlutamate racemase / 0.744
2pvh P19Casein kinase II subunit alpha 2.7.11.1 0.744
2q5y TYR_GLY_LEUNuclear pore complex protein Nup98-Nup96 / 0.744
2q6h CXXNa(+):neurotransmitter symporter (Snf family) / 0.744
2qei CXXNa(+):neurotransmitter symporter (Snf family) / 0.744
2qhw PZZBasic phospholipase A2 VRV-PL-VIIIa 3.1.1.4 0.744
2r9k SGIBeta-galactoside-specific lectin 1 / 0.744
2rbe ZMGCorticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
2std CRPScytalone dehydratase 4.2.1.94 0.744
2uxp CLMHTH-type transcriptional regulator TtgR / 0.744
2v61 C18Amine oxidase [flavin-containing] B 1.4.3.4 0.744
2vcg S17Histone deacetylase-like amidohydrolase 3.5.1 0.744
2vcz VC3Hematopoietic prostaglandin D synthase / 0.744
2vg5 NNCGag-Pol polyprotein 2.7.7.49 0.744
2vg7 NNIGag-Pol polyprotein 2.7.7.49 0.744
2vq5 LDPS-norcoclaurine synthase / 0.744
2vuk P83Cellular tumor antigen p53 / 0.744
2w0b CMWLanosterol 14-alpha demethylase 1.14.13.70 0.744
2w6c BM4Acetylcholinesterase 3.1.1.7 0.744
2wu4 HBPAcetylcholinesterase 3.1.1.7 0.744
2xae 2XAKinesin-like protein KIF11 / 0.744
2xby 63CCoagulation factor X 3.4.21.6 0.744
2xc5 OYJCoagulation factor X 3.4.21.6 0.744
2xiy XIYSerine/threonine-protein kinase pim-1 2.7.11.1 0.744
2xuf TZ4Acetylcholinesterase 3.1.1.7 0.744
2xuk TZ5Acetylcholinesterase 3.1.1.7 0.744
2xuo TZ4Acetylcholinesterase 3.1.1.7 0.744
2xys SY9Soluble acetylcholine receptor / 0.744
2y3r TIRTamL / 0.744
2y3s TIRTamL / 0.744
2ycs NXPSerine/threonine-protein kinase Chk2 2.7.11.1 0.744
2yeg XQGHeat shock protein HSP 90-alpha / 0.744
2yne YNEGlycylpeptide N-tetradecanoyltransferase / 0.744
3aba FLICytochrome P450 / 0.744
3acw 651Dehydrosqualene synthase / 0.744
3aqa BYHBromodomain-containing protein 2 / 0.744
3ar4 TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
3ar6 TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 3.6.3.8 0.744
3arq DM5Chitinase A / 0.744
3ayg HQONitric oxide reductase / 0.744
3bi4 298Polyamine oxidase FMS1 / 0.744
3bpt QUE3-hydroxyisobutyryl-CoA hydrolase, mitochondrial 3.1.2.4 0.744
3br3 ETHTH-type transcriptional regulator QacR / 0.744
3c4e C4ESerine/threonine-protein kinase pim-1 2.7.11.1 0.744
3cgy RDCVirulence sensor histidine kinase PhoQ 2.7.13.3 0.744
3clx X22E3 ubiquitin-protein ligase XIAP 6.3.2 0.744
3d27 W29Methionine aminopeptidase / 0.744
3d73 NBBPheromone-binding protein ASP1 / 0.744
3d74 NBBPheromone-binding protein ASP1 / 0.744
3dl9 V2HVitamin D 25-hydroxylase / 0.744
3dnd LL2cAMP-dependent protein kinase catalytic subunit alpha 2.7.11.11 0.744
3dy8 IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3dyq IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3ej0 11XInorganic pyrophosphatase / 0.744
3ey4 352Corticosteroid 11-beta-dehydrogenase isozyme 1 1.1.1.146 0.744
3f3y 4OABile salt sulfotransferase 2.8.2.14 0.744
3foo PXXSoluble cytochrome b562 / 0.744
3ful 52DLeukotriene A-4 hydrolase 3.3.2.6 0.744
3gcm 5GPPolyribonucleotide nucleotidyltransferase / 0.744
3gw9 VNILanosterol 14-alpha-demethylase / 0.744
3gwu SRENa(+):neurotransmitter symporter (Snf family) / 0.744
3hxe BD8Geranylgeranyl transferase type-2 subunit beta 2.5.1.60 0.744
3hz1 37DHeat shock protein HSP 90-alpha / 0.744
3i64 DNA2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase / 0.744
3ibd CPZCytochrome P450 2B6 1.14.13 0.744
3il1 B5DGlutamate receptor 2 / 0.744
3inj BXBAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.744
3inl BXBAldehyde dehydrogenase, mitochondrial 1.2.1.3 0.744
3ipt EQUSteroid Delta-isomerase 5.3.3.1 0.744
3itu IBMcGMP-dependent 3',5'-cyclic phosphodiesterase 3.1.4.17 0.744
3iu9 T07Methionine aminopeptidase 2 / 0.744
3iw8 HIZMitogen-activated protein kinase 14 / 0.744
3jq8 DX3Pteridine reductase, putative / 0.744
3lal KRVGag-Pol polyprotein 2.7.7.49 0.744
3lam KRPGag-Pol polyprotein 2.7.7.49 0.744
3lw0 CCXInsulin-like growth factor 1 receptor 2.7.10.1 0.744
3lzz GDPUncharacterized protein / 0.744
3m6g LO3Actin, alpha skeletal muscle / 0.744
3mdm FJZCholesterol 24-hydroxylase / 0.744
3mj5 GRMReplicase polyprotein 1a 3.4.22 0.744
3mla JJZProbable nicotinate-nucleotide adenylyltransferase / 0.744
3mpe N2ACathepsin S 3.4.22.27 0.744
3my5 RFZCyclin-dependent kinase 2 2.7.11.22 0.744
3myu VIBHigh affinity transport system protein p37 / 0.744
3njo P2MAbscisic acid receptor PYR1 / 0.744
3nlq JRRNitric oxide synthase, brain 1.14.13.39 0.744
3nly 3XCNitric oxide synthase, brain 1.14.13.39 0.744
3nzk C90UDP-3-O-acyl-N-acetylglucosamine deacetylase / 0.744
3o73 O73Ribosyldihydronicotinamide dehydrogenase [quinone] / 0.744
3oht 1N1Mitogen-activated protein kinase / 0.744
3oq6 PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
3owy EQUSteroid Delta-isomerase 5.3.3.1 0.744
3p8h P8HLethal(3)malignant brain tumor-like protein 1 / 0.744
3p99 LNPLanosterol 14-alpha-demethylase / 0.744
3pah XDEPhenylalanine-4-hydroxylase 1.14.16.1 0.744
3pcf FHBProtocatechuate 3,4-dioxygenase beta chain 1.13.11.3 0.744
3pm1 ETHTH-type transcriptional regulator QacR / 0.744
3pmu F7LEndothiapepsin 3.4.23.22 0.744
3psu LJGGag-Pol polyprotein 3.4.23.16 0.744
3pyy 3YYTyrosine-protein kinase ABL1 2.7.10.2 0.744
3q92 XNBKetohexokinase / 0.744
3qgf 46FGenome polyprotein 2.7.7.48 0.744
3qi4 IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A / 0.744
3qm4 PN0Cytochrome P450 2D6 / 0.744
3rqj Y2BNitric oxide synthase, brain 1.14.13.39 0.744
3s1c ZIRCytokinin dehydrogenase 1 1.5.99.12 0.744
3sff 0DIHistone deacetylase 8 3.5.1.98 0.744
3sfh 1DIHistone deacetylase 8 3.5.1.98 0.744
3svp JK5Nitric oxide synthase, brain 1.14.13.39 0.744
3svq JK4Nitric oxide synthase, brain 1.14.13.39 0.744
3szf DCQSulfide-quinone reductase / 0.744
3t11 3T1Gag-Pol polyprotein 3.4.23.16 0.744
3tda PN0Cytochrome P450 2D6 / 0.744
3tdj 3TJGlutamate receptor 2 / 0.744
3tk3 CPZCytochrome P450 2B4 1.14.14.1 0.744
3u3o 3QVSulfotransferase 1A1 2.8.2.1 0.744
3u78 E67Lysine-specific demethylase 7A 1.14.11 0.744
3ua5 06XCytochrome P450 2B6 1.14.13 0.744
3uft HW7Nitric oxide synthase, brain 1.14.13.39 0.744
3v1s 0LHStrictosidine synthase 4.3.3.2 0.744
3vev 0H4Glucokinase 2.7.1.2 0.744
3wsb RWZFarnesyltransferase, putative / 0.744
3zpq XF5Beta-1 adrenergic receptor / 0.744
3zr7 OR8Progesterone receptor / 0.744
3zra ORBProgesterone receptor / 0.744
3zrb ORCProgesterone receptor / 0.744
4a9r RU5Serine/threonine-protein kinase Chk2 2.7.11.1 0.744
4ahv Z5PGag-Pol polyprotein / 0.744
4apu OR8Progesterone receptor / 0.744
4as7 6LXKinesin-like protein KIF11 / 0.744
4awg CI3Polymerase acidic protein / 0.744
4b6u M7GEukaryotic translation initiation factor 4E type 3 / 0.744
4b71 DJLGenome polyprotein 3.4.21.98 0.744
4b76 PW1Genome polyprotein 3.4.21.98 0.744
4b7z Q4QAcetylcholinesterase 3.1.1.7 0.744
4bbh YBNGlycylpeptide N-tetradecanoyltransferase / 0.744
4bls APCNTPase P4 / 0.744
4chy C5QIntegrase / 0.744
4dij BLFE3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
4dkp 0LLEnvelope glycoprotein gp160 / 0.744
4dku 0KUEnvelope glycoprotein gp160 / 0.744
4dkv 0KWEnvelope glycoprotein gp160 / 0.744
4dlj 6RGMitogen-activated protein kinase 14 / 0.744
4dwv PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
4e0u 0MVCyclic dipeptide N-prenyltransferase / 0.744
4e6a 0O9Mitogen-activated protein kinase 14 / 0.744
4ea0 651Dehydrosqualene synthase / 0.744
4eh6 IRGMitogen-activated protein kinase 14 / 0.744
4eh7 0OOMitogen-activated protein kinase 14 / 0.744
4ejv LCLTranscriptional regulator TcaR / 0.744
4erw STUCyclin-dependent kinase 2 2.7.11.22 0.744
4fxy 0W2Neurolysin, mitochondrial 3.4.24.16 0.744
4g09 0VDHistidinol dehydrogenase / 0.744
4g48 PZBMycocyclosin synthase 1.14.21.9 0.744
4g7g VFVLanosterol 14-alpha-demethylase / 0.744
4hmb PZZPhospholipase A2 VRV-PL-VIIIa / 0.744
4hyi 1AOSerine/threonine-protein kinase Chk1 2.7.11.1 0.744
4i1r LZUMucosa-associated lymphoid tissue lymphoma translocation protein 1 3.4.22 0.744
4iyg 1HUStrictosidine synthase 4.3.3.2 0.744
4j6d TESCytochrome P450 monooxygenase / 0.744
4j7d I31E3 ubiquitin-protein ligase Mdm2 6.3.2 0.744
4jlj 1NMDeoxycytidine kinase 2.7.1.74 0.744
4jlt 8PRCytochrome P450 2B4 1.14.14.1 0.744
4jr5 1LSNicotinamide phosphoribosyltransferase 2.4.2.12 0.744
4kfo 1QSNicotinamide phosphoribosyltransferase 2.4.2.12 0.744
4kqg DMDNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase 2.4.2.21 0.744
4lg5 A1OAbscisic acid receptor PYL2 / 0.744
4lmu QUESerine/threonine-protein kinase pim-1 2.7.11.1 0.744
4lxj LANLanosterol 14-alpha demethylase 1.14.13.70 0.744
4m48 21BSodium-dependent dopamine transporter / 0.744
4man 1Y1Apoptosis regulator Bcl-2 / 0.744
4mfe BTNPyruvate carboxylase / 0.744
4mme 29QNa(+):neurotransmitter symporter (Snf family) / 0.744
4n6h EJ4Delta-type opioid receptor / 0.744
4nbh 9CATerminal oxygenase component of carbazole / 0.744
4ng5 PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
4nh9 2LCEndoplasmin / 0.744
4nkv AERSteroid 17-alpha-hydroxylase/17,20 lyase / 0.744
4o78 SAVBromodomain-containing protein 4 / 0.744
4pah LNRPhenylalanine-4-hydroxylase 1.14.16.1 0.744
4ple CPSNuclear receptor subfamily 5 group A member 2 / 0.744
4qem HC4Phospholipase A2 VRV-PL-VIIIa / 0.744
4qer STLPhospholipase A2 VRV-PL-VIIIa / 0.744
4qjq OTRLactoperoxidase / 0.744
4r20 AERCytochrome P450 family 17 polypeptide 2 / 0.744
4rgs V55Repressor protein / 0.744
4ryv ZEAProtein LlR18A / 0.744
4uym VOR14-alpha sterol demethylase Cyp51B / 0.744
4xoq F42Coenzyme F420:L-glutamate ligase / 0.744
4xp4 COCSodium-dependent dopamine transporter / 0.744
4zp0 DXCMultidrug transporter MdfA / 0.744
5a4w QCTGlutathione S-transferase F2 2.5.1.18 0.744
5alu HD2Bifunctional epoxide hydrolase 2 3.1.3.76 0.744
5c8a 5ADProbable transcriptional regulator / 0.744
5cdg PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5cds PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5cdt PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5kj6 PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5kjc PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
5kje PFBAlcohol dehydrogenase E chain 1.1.1.1 0.744
6std MS2Scytalone dehydratase 4.2.1.94 0.744
7std CRPScytalone dehydratase 4.2.1.94 0.744
5l7d CLRSmoothened homolog / 0.744
5dhh DGWNociceptin receptor / 0.744
5dhg DGVNociceptin receptor / 0.744
4ej4 EJ4Delta-type opioid receptor / 0.744
3ish FADThioredoxin reductase 1.8.1.9 0.743
1f3p FADFerredoxin reductase / 0.742
4gcm FADThioredoxin reductase 1.8.1.9 0.738
2gr3 FADFerredoxin reductase / 0.734
2gr0 FADFerredoxin reductase / 0.733
2yvf FADFerredoxin reductase / 0.733
4nte FADDepH / 0.733
3lzx FADFerredoxin--NADP reductase 2 1.18.1.2 0.732
4h4w FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.732
1w4x FADPhenylacetone monooxygenase 1.14.13.92 0.730
2v3a FADRubredoxin-NAD(+) reductase 1.18.1.1 0.727
3cgb FADCoenzyme A disulfide reductase / 0.727
3cgc FADCoenzyme A disulfide reductase / 0.727
2q0k FADThioredoxin reductase 1.8.1.9 0.726
2xve FADPutative flavin-containing monooxygenase / 0.726
3lb8 FADPutidaredoxin reductase 1.18.1.5 0.726
4ntc FADThioredoxin reductase gliT / 0.726
1d7y FADFerredoxin reductase / 0.725
1grb FADGlutathione reductase, mitochondrial 1.8.1.7 0.724
3ab1 FADFerredoxin--NADP reductase 1.18.1.2 0.722
2ylr FADPhenylacetone monooxygenase 1.14.13.92 0.721
3ad9 NADSubunit alpha of sarocosine oxidase / 0.721
2gqw FADFerredoxin reductase / 0.720
4h4r FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.720
4h4t FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.720
4h4v FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.720
4h4x FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.720
4h4z FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.719
1cl0 FADThioredoxin reductase 1.8.1.9 0.718
1tdf FADThioredoxin reductase 1.8.1.9 0.718
1f8s FADL-amino-acid oxidase 1.4.3.2 0.717
2iid FADL-amino-acid oxidase 1.4.3.2 0.716
2ylx FADPhenylacetone monooxygenase 1.14.13.92 0.715
4jn9 FADDepH / 0.715
5j60 FADThioredoxin reductase / 0.715
1trb FADThioredoxin reductase 1.8.1.9 0.714
2yg5 FADPutrescine oxidase / 0.714
2yg6 FADPutrescine oxidase / 0.714
4d04 FADPhenylacetone monooxygenase 1.14.13.92 0.714
4h4p FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.714
4d03 FADPhenylacetone monooxygenase 1.14.13.92 0.713
2du8 FADD-amino-acid oxidase 1.4.3.3 0.712
3nlc FADUncharacterized protein / 0.712
3uox FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.712
2ym1 FADPhenylacetone monooxygenase 1.14.13.92 0.711
3gwf FADCyclohexanone monooxygenase / 0.711
3uov FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.711
2ar8 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.710
2eq6 FADDihydrolipoyl dehydrogenase / 0.709
1q1r FADPutidaredoxin reductase 1.18.1.5 0.708
1tde FADThioredoxin reductase 1.8.1.9 0.708
2eq8 FADDihydrolipoyl dehydrogenase / 0.708
3ef6 FADToluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component 1.18.1.3 0.708
2gh5 FADGlutathione reductase, mitochondrial 1.8.1.7 0.707
3kve FADL-amino-acid oxidase / 0.707
2jae FADL-amino acid oxidase / 0.706
3ada NADSubunit alpha of sarocosine oxidase / 0.706
4h50 FADBiphenyl dioxygenase ferredoxin reductase subunit / 0.706
5fs9 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.706
5fs6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.705
4up3 FADThioredoxin reductase / 0.704
2q0l FADThioredoxin reductase 1.8.1.9 0.703
4jnq FDAThioredoxin reductase / 0.703
1djq ADPTrimethylamine dehydrogenase 1.5.8.2 0.702
1o94 ADPTrimethylamine dehydrogenase 1.5.8.2 0.702
2ylw FADPhenylacetone monooxygenase 1.14.13.92 0.701
3cge FADCoenzyme A disulfide reductase / 0.701
4cnk FADL-amino acid oxidase / 0.701
2xvf FADPutative flavin-containing monooxygenase / 0.700
2yg4 FADPutrescine oxidase / 0.700
3cgd FADCoenzyme A disulfide reductase / 0.700
3rha FDAPutrescine oxidase / 0.700
3t2z FADSulfide-quinone reductase / 0.700
2aqj FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.699
2tmd ADPTrimethylamine dehydrogenase 1.5.8.2 0.699
2zbw FADFerredoxin--NADP reductase / 0.699
3djg FADGlutathione reductase, mitochondrial 1.8.1.7 0.699
3t2k FADSulfide-quinone reductase / 0.699
4guu FA9Lysine-specific histone demethylase 1B 1 0.699
1djn ADPTrimethylamine dehydrogenase 1.5.8.2 0.698
1k4q FADGlutathione reductase, mitochondrial 1.8.1.7 0.697
1m6i FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.697
2qa1 FADPgaE / 0.697
4bv6 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.697
4fwf FADLysine-specific histone demethylase 1B 1 0.697
2gv8 FADThiol-specific monooxygenase 1.14.13 0.696
1gre FADGlutathione reductase, mitochondrial 1.8.1.7 0.695
1ps9 FAD2,4-dienoyl-CoA reductase 1.3.1.34 0.695
2gvc FADThiol-specific monooxygenase 1.14.13 0.695
2yls FADPhenylacetone monooxygenase 1.14.13.92 0.695
1e1l FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.694
1gsn FADGlutathione reductase, mitochondrial 1.8.1.7 0.694
1zk7 FADMercuric reductase 1.16.1.1 0.694
1gra FADGlutathione reductase, mitochondrial 1.8.1.7 0.693
3djj FADGlutathione reductase, mitochondrial 1.8.1.7 0.693
3dk4 FADGlutathione reductase, mitochondrial 1.8.1.7 0.692
4fwe FADLysine-specific histone demethylase 1B 1 0.692
1zx9 FADMercuric reductase 1.16.1.1 0.690
2x8g FADThioredoxin glutathione reductase / 0.690
4bur FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.690
4jdr FADDihydrolipoyl dehydrogenase 1.8.1.4 0.690
5fs8 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.690
1lqu FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.689
3dk8 FADGlutathione reductase, mitochondrial 1.8.1.7 0.688
3klj FADNADH-rubredoxin oxidoreductase 1.18.1.1 0.688
4gr1 FADGlutathione reductase, mitochondrial 1.8.1.7 0.688
1e6e FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.687
3k7m FAD6-hydroxy-L-nicotine oxidase / 0.687
3sz0 FADSulfide-quinone reductase / 0.687
1d4d FADFumarate reductase flavoprotein subunit 1.3.5.4 0.686
1jnz FADAdenylylsulfate reductase, subunit A (AprA) / 0.686
2cul FADGidA-related protein / 0.686
2yg3 FADPutrescine oxidase / 0.685
4k5r FADOxygenase / 0.685
1geu FADGlutathione reductase 1.8.1.7 0.684
3kpk FADSulfide-quinone reductase / 0.683
4fk1 FADPutative thioredoxin reductase / 0.683
4lii FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.683
4z44 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.682
1grh FADGlutathione reductase, mitochondrial 1.8.1.7 0.681
3syi FADSulfide-quinone reductase / 0.681
4a5l FADThioredoxin reductase / 0.681
1bwc FADGlutathione reductase, mitochondrial 1.8.1.7 0.680
1i8t FADUDP-galactopyranose mutase 5.4.99.9 0.680
3dk9 FADGlutathione reductase, mitochondrial 1.8.1.7 0.680
4ntd FADThioredoxin reductase / 0.680
1dnc FADGlutathione reductase, mitochondrial 1.8.1.7 0.679
1qo8 FADFumarate reductase flavoprotein subunit / 0.679
2apg FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.679
2i0z FADNAD(FAD)-utilizing dehydrogenases / 0.679
2jkc FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.679
2yg7 FADPutrescine oxidase / 0.679
4b1b FADThioredoxin reductase 1.8.1.9 0.679
4la1 FADThioredoxin glutathione reductase / 0.679
4z2t FAD2-hydroxybiphenyl-3-monooxygenase / 0.679
1b8s FADCholesterol oxidase 1.1.3.6 0.678
1mxt FAECholesterol oxidase 1.1.3.6 0.678
2ard FDAFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.678
3oz2 FADDigeranylgeranylglycerophospholipid reductase / 0.678
3r9u FADThioredoxin reductase / 0.678
4rek FADCholesterol oxidase 1.1.3.6 0.678
1n1p FADCholesterol oxidase 1.1.3.6 0.677
2gew FADCholesterol oxidase 1.1.3.6 0.677
2rgh FADAlpha-Glycerophosphate Oxidase / 0.677
2ylt FADPhenylacetone monooxygenase 1.14.13.92 0.677
2ylz FADPhenylacetone monooxygenase 1.14.13.92 0.677
3oc4 FADOxidoreductase, pyridine nucleotide-disulfide family / 0.677
4j33 FADKynurenine 3-monooxygenase / 0.677
4mok FADPyranose 2-oxidase / 0.677
1h7w FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.676
2whd FADThioredoxin reductase / 0.676
3k4c FADPyranose 2-oxidase / 0.676
3pvc FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.676
3qfa FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.676
4yjd FADD-amino-acid oxidase 1.4.3.3 0.676
2nvk FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.674
2v6o FADThioredoxin glutathione reductase / 0.674
2wes FADTryptophan 5-halogenase / 0.674
3int FDAUDP-galactopyranose mutase 5.4.99.9 0.674
1grg FADGlutathione reductase, mitochondrial 1.8.1.7 0.673
1v59 FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.673
2qa2 FADPolyketide oxygenase CabE / 0.673
3fbs FADOxidoreductase / 0.673
3grs FADGlutathione reductase, mitochondrial 1.8.1.7 0.673
3rnm FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.673
3urh FADDihydrolipoyl dehydrogenase / 0.673
2ym2 FADPhenylacetone monooxygenase 1.14.13.92 0.672
2yr4 FADPhenylalanine 2-monooxygenase precursor 1.13.12.9 0.672
3sgl FADtRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC / 0.672
3t14 FADSulfide-quinone reductase / 0.672
3up5 FAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase 1.14.13.160 0.672
3dgz FADThioredoxin reductase 2, mitochondrial 1.8.1.9 0.671
4z24 FADPutative GMC-type oxidoreductase R135 1 0.671
1y56 ATPUncharacterized protein / 0.670
3cuk FADD-amino-acid oxidase 1.4.3.3 0.670
4o5u FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.670
2bry FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.669
2zzc FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.669
4a65 FADThioredoxin reductase / 0.669
5buk FADFADH2-dependent halogenase / 0.669
3k30 ADPHistamine dehydrogenase / 0.668
4gde FDAUDP-galactopyranose mutase / 0.668
4nzh FADL-ornithine N(5)-monooxygenase / 0.668
1ng3 FADGlycine oxidase 1.4.3.19 0.667
2ywl FADThioredoxin reductase related protein / 0.667
3itj FADThioredoxin reductase 1 1.8.1.9 0.667
3t37 FADPyridoxine 4-oxidase / 0.667
4cy8 FDA2-hydroxybiphenyl-3-monooxygenase / 0.667
4hb9 FADUncharacterized protein / 0.667
4hsu FADLysine-specific histone demethylase 1B 1 0.667
4ap3 FADSteroid monooxygenase / 0.666
2wow FADTrypanothione reductase / 0.665
3t2y FADSulfide-quinone reductase / 0.665
1cjc FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.664
1vdc FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.664
2cfy FADThioredoxin reductase 1, cytoplasmic 1.8.1.9 0.664
2cvj FADThioredoxin reductase related protein / 0.664
2xls FADPutative flavin-containing monooxygenase / 0.664
4gus FADLysine-specific histone demethylase 1B 1 0.664
4j57 FADThioredoxin reductase 2 1.8.1.9 0.664
1n4u FAECholesterol oxidase 1.1.3.6 0.663
1n4w FADCholesterol oxidase 1.1.3.6 0.663
3b6d FAECholesterol oxidase 1.1.3.6 0.663
3gyi FADCholesterol oxidase 1.1.3.6 0.663
4k2x FADPolyketide oxygenase/hydroxylase / 0.663
4u2s FDACholesterol oxidase 1.1.3.6 0.663
4x9m FADUncharacterized protein MG039 homolog / 0.663
4xwr FADCholesterol oxidase 1.1.3.6 0.663
4xxg FADCholesterol oxidase 1.1.3.6 0.663
1b4v FADCholesterol oxidase 1.1.3.6 0.662
1ju2 FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.662
2eq7 FADDihydrolipoyl dehydrogenase / 0.662
2hqm FADGlutathione reductase 1.8.1.7 0.662
3cox FADCholesterol oxidase 1.1.3.6 0.662
3gyj FADCholesterol oxidase 1.1.3.6 0.662
4ccq FADThioredoxin reductase / 0.662
5cku FADL-ornithine N(5)-monooxygenase / 0.662
2xlp FADPutative flavin-containing monooxygenase / 0.661
3bg7 FADPyranose 2-oxidase / 0.661
3gdp FAD(R)-mandelonitrile lyase 2 4.1.2.10 0.661
3ute FADUDP-galactopyranose mutase / 0.661
4dsg FADUncharacterized protein / 0.661
4jq9 FADDihydrolipoyl dehydrogenase / 0.661
4tm1 FDAKtzI / 0.661
4usr FADMonooxygenase / 0.661
4x9n FADUncharacterized protein MG039 homolog / 0.661
1acj THAAcetylcholinesterase 3.1.1.7 0.660
1c3x 8IGPurine nucleoside phosphorylase 2.4.2.1 0.660
1d3p BT3Prothrombin 3.4.21.5 0.660
1e1n FADNADPH:adrenodoxin oxidoreductase, mitochondrial 1.18.1.6 0.660
1h46 RNPGlucanase / 0.660
1lqd CMICoagulation factor X 3.4.21.6 0.660
1q0r AKTAclacinomycin methylesterase RdmC 3.1.1.95 0.660
1q0z AKAAclacinomycin methylesterase RdmC 3.1.1.95 0.660
1tvv CB3Thymidylate synthase / 0.660
1yho TRRDihydrofolate reductase 1.5.1.3 0.660
1zzq DP9Nitric oxide synthase, brain 1.14.13.39 0.660
2c6h PXICytochrome P450 monooxygenase PikC / 0.660
2c7g FADNADPH-ferredoxin reductase FprA 1.18.1.2 0.660
2cd8 PXICytochrome P450 monooxygenase PikC / 0.660
2cjp VPREpoxide hydrolase / 0.660
2oae AILDipeptidyl peptidase 4 / 0.660
2pjl 047Steroid hormone receptor ERR1 / 0.660
2pks G44Prothrombin 3.4.21.5 0.660
2qjp ANJCytochrome b / 0.660
2qmz LDPRibosyldihydronicotinamide dehydrogenase [quinone] / 0.660
2tpr FADTrypanothione reductase 1.8.1.12 0.660
2v57 PRLTetR family transcriptional regulator / 0.660
2v5z SAGAmine oxidase [flavin-containing] B 1.4.3.4 0.660
2va6 H24Beta-secretase 1 3.4.23.46 0.660
2va7 C27Beta-secretase 1 3.4.23.46 0.660
2vzm NRBCytochrome P450 monooxygenase PikC / 0.660
2wd8 VGFPteridine reductase / 0.660
2wog ZZDKinesin-like protein KIF11 / 0.660
2ze2 T27Gag-Pol polyprotein 2.7.7.49 0.660
3bc4 LLGGag-Pol polyprotein 3.4.23.16 0.660
3bt9 DEQHTH-type transcriptional regulator QacR / 0.660
3btj DEQHTH-type transcriptional regulator QacR / 0.660
3cxw 7CPSerine/threonine-protein kinase pim-1 2.7.11.1 0.660
3cy2 MB9Serine/threonine-protein kinase pim-1 2.7.11.1 0.660
3fun 798Leukotriene A-4 hydrolase 3.3.2.6 0.660
3g72 A6TRenin 3.4.23.15 0.660
3gn2 AX8Pteridine reductase / 0.660
3iu8 T03Methionine aminopeptidase 2 / 0.660
3ken ZZDKinesin-like protein KIF11 / 0.660
3kjm 245Cytokinin dehydrogenase 1 1.5.99.12 0.660
3ko0 TFPProtein S100-A4 / 0.660
3l5b BDOBeta-secretase 1 3.4.23.46 0.660
3m0w P77Protein S100-A4 / 0.660
3nxu RITCytochrome P450 3A4 / 0.660
3pld F90Endothiapepsin 3.4.23.22 0.660
3pll F06Endothiapepsin 3.4.23.22 0.660
3qai XNNKetohexokinase / 0.660
3t40 3RGIndole-3-glycerol phosphate synthase 4.1.1.48 0.660
3wb4 0B3Beta-secretase 1 3.4.23.46 0.660
4a51 DQ8Kinesin-like protein KIF11 / 0.660
4bbg V02Kinesin-like protein KIF11 / 0.660
4c59 FEFCyclin-G-associated kinase 2.7.11.1 0.660
4cx4 HW9Nitric oxide synthase, brain 1.14.13.39 0.660
4eh4 IRGMitogen-activated protein kinase 14 / 0.660
4eip K2CPutative FAD-monooxygenase / 0.660
4enh FVXCholesterol 24-hydroxylase / 0.660
4ha5 13WBeta-secretase 1 3.4.23.46 0.660
4jhz 1KVBeta-glucuronidase 3.2.1.31 0.660
4lm5 Q17Serine/threonine-protein kinase pim-1 2.7.11.1 0.660
4m6p 20RNicotinamide phosphoribosyltransferase 2.4.2.12 0.660
4mm4 8PRNa(+):neurotransmitter symporter (Snf family) / 0.660
4mmd 29ENa(+):neurotransmitter symporter (Snf family) / 0.660
4oal 245Cytokinin dehydrogenase 4 / 0.660
4uco IWHDNA ligase / 0.660
4y3q F02Endothiapepsin 3.4.23.22 0.660
4y4j LNREndothiapepsin 3.4.23.22 0.660
4z43 FADFlavin-dependent tryptophan halogenase PrnA 1.14.19.9 0.660
5d7p OCZNAD-dependent protein deacetylase sirtuin-2 3.5.1 0.660
1ger FADGlutathione reductase 1.8.1.7 0.659
3pl8 FADPyranose 2-oxidase / 0.659
2yqu FADDihydrolipoyl dehydrogenase / 0.658
1get FADGlutathione reductase 1.8.1.7 0.657
1gv4 FADApoptosis-inducing factor 1, mitochondrial 1.1.1 0.657
1zmc FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.657
2x8h FADThioredoxin glutathione reductase / 0.657
3utf FDAUDP-galactopyranose mutase / 0.657
3utg FDAUDP-galactopyranose mutase / 0.657
2fja FADAdenylylsulfate reductase, subunit A (AprA) / 0.656
5eow FAD6-hydroxynicotinate 3-monooxygenase 1.14.13.114 0.656
1mo9 FAD2-oxopropyl-CoM reductase, carboxylating 1.8.1.5 0.655
3axb FADPutative oxidoreductase / 0.655
3uth FDAUDP-galactopyranose mutase / 0.655
4o5q FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.655
4ykf FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.655
1fl2 FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.654
1wam FADUDP-galactopyranose mutase 5.4.99.9 0.654
1zmd FADDihydrolipoyl dehydrogenase, mitochondrial 1.8.1.4 0.654
2e1m FADL-glutamate oxidase / 0.654
3dh9 FADThioredoxin reductase 1, mitochondrial 1.8.1.9 0.654
4ap1 FADSteroid monooxygenase / 0.654
4mih FADPyranose 2-oxidase 1.1.3.10 0.654
4ykg FADAlkyl hydroperoxide reductase subunit F 1.8.1 0.654
4z26 FADPutative GMC-type oxidoreductase R135 1 0.654
4u8o FDAUDP-galactopyranose mutase / 0.653
2bra FAD[F-actin]-methionine sulfoxide oxidase MICAL1 1.14.13 0.652
3kyb FADUDP-galactopyranose mutase 5.4.99.9 0.652
4mo2 FADUDP-galactopyranose mutase / 0.652
1ges FADGlutathione reductase 1.8.1.7 0.651
1v0j FADUDP-galactopyranose mutase 5.4.99.9 0.651
1gte FADDihydropyrimidine dehydrogenase [NADP(+)] 1.3.1.2 0.650
2fje FADAdenylylsulfate reductase, subunit A (AprA) / 0.650
2wet FADTryptophan 5-halogenase / 0.650
3fpz AHZThiamine thiazole synthase / 0.650
3vqr FADPutative oxidoreductase / 0.650
4b63 FADL-ornithine N(5)-monooxygenase / 0.650
4ynt FDAGlucose oxidase, putative / 0.650
4yry FADGlutamate synthase, beta subunit / 0.650