sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2qe4 | JJ3 | Estrogen receptor |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2qe4 | JJ3 | Estrogen receptor | / | 1.000 | |
| 1yin | CM3 | Estrogen receptor | / | 0.629 | |
| 2fsz | OHT | Estrogen receptor beta | / | 0.626 | |
| 2jf9 | OHT | Estrogen receptor | / | 0.624 | |
| 2bj4 | OHT | Estrogen receptor | / | 0.621 | |
| 2pog | WST | Estrogen receptor | / | 0.614 | |
| 1nde | MON | Estrogen receptor beta | / | 0.612 | |
| 1uom | PTI | Estrogen receptor | / | 0.602 | |
| 1sj0 | E4D | Estrogen receptor | / | 0.598 | |
| 1err | RAL | Estrogen receptor | / | 0.595 | |
| 1xp6 | AIU | Estrogen receptor | / | 0.591 | |
| 2p7z | OHT | Estrogen-related receptor gamma | / | 0.590 | |
| 2fai | 459 | Estrogen receptor | / | 0.589 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.583 | |
| 1qkn | RAL | Estrogen receptor beta | / | 0.582 | |
| 2qgt | EED | Estrogen receptor | / | 0.578 | |
| 4iv4 | 1GS | Estrogen receptor | / | 0.576 | |
| 4iw6 | 1GU | Estrogen receptor | / | 0.572 | |
| 2jfa | RAL | Estrogen receptor | / | 0.571 | |
| 1zky | 689 | Estrogen receptor | / | 0.569 | |
| 1g50 | EST | Estrogen receptor | / | 0.566 | |
| 1yim | CM4 | Estrogen receptor | / | 0.556 | |
| 2gpu | OHT | Estrogen-related receptor gamma | / | 0.552 | |
| 3l03 | 4OH | Estrogen receptor | / | 0.552 | |
| 3uud | EST | Estrogen receptor | / | 0.551 | |
| 4a2j | AS0 | Progesterone receptor | / | 0.550 | |
| 4iw8 | KN3 | Estrogen receptor | / | 0.549 | |
| 5dxg | EST | Estrogen receptor | / | 0.549 | |
| 2p15 | EZT | Estrogen receptor | / | 0.548 | |
| 1l2i | ETC | Estrogen receptor | / | 0.547 | |
| 1xqc | AEJ | Estrogen receptor | / | 0.545 | |
| 2b1z | 17M | Estrogen receptor | / | 0.541 | |
| 2ewp | TXF | Estrogen-related receptor gamma | / | 0.541 | |
| 2ocf | EST | Estrogen receptor | / | 0.541 | |
| 3q95 | ESL | Estrogen receptor | / | 0.541 | |
| 1xpc | AIT | Estrogen receptor | / | 0.538 | |
| 3oll | EST | Estrogen receptor beta | / | 0.538 | |
| 4iu7 | 1GM | Estrogen receptor | / | 0.538 | |
| 4j24 | EST | Estrogen receptor beta | / | 0.538 | |
| 5dx3 | EST | Estrogen receptor | / | 0.538 | |
| 2giu | FBR | Estrogen receptor beta | / | 0.531 | |
| 2j7y | E3O | Estrogen receptor beta | / | 0.530 | |
| 1s9q | OHT | Estrogen-related receptor gamma | / | 0.529 | |
| 1u9e | 397 | Estrogen receptor beta | / | 0.528 | |
| 1x7j | GEN | Estrogen receptor beta | / | 0.528 | |
| 2qa8 | GEN | Estrogen receptor | / | 0.528 | |
| 4iv2 | 1GR | Estrogen receptor | / | 0.528 | |
| 4ivw | 1GJ | Estrogen receptor | / | 0.526 | |
| 1xp1 | AIH | Estrogen receptor | / | 0.525 | |
| 2jj3 | JJ3 | Estrogen receptor beta | / | 0.525 | |
| 2ovm | AS0 | Progesterone receptor | / | 0.518 | |
| 1u3s | 797 | Estrogen receptor beta | / | 0.517 | |
| 4zn7 | DES | Estrogen receptor | / | 0.517 | |
| 5ai5 | BSU | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.517 | |
| 1gs4 | ZK5 | Androgen receptor | / | 0.516 | |
| 1u3r | 338 | Estrogen receptor beta | / | 0.515 | |
| 1x76 | 697 | Estrogen receptor beta | / | 0.515 | |
| 2yja | EST | Estrogen receptor | / | 0.515 | |
| 3erd | DES | Estrogen receptor | / | 0.514 | |
| 2acw | UPG | Glycosyltransferase | / | 0.513 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.511 | |
| 3ols | EST | Estrogen receptor beta | / | 0.510 | |
| 4pp6 | STL | Estrogen receptor | / | 0.510 | |
| 1nhz | 486 | Glucocorticoid receptor | / | 0.509 | |
| 1yy4 | 4NA | Estrogen receptor beta | / | 0.508 | |
| 2w8y | 486 | Progesterone receptor | / | 0.506 | |
| 3cse | N22 | Uncharacterized protein | / | 0.506 | |
| 4pxm | EST | Estrogen receptor | / | 0.504 | |
| 4iui | 1GQ | Estrogen receptor | / | 0.503 | |
| 1s9p | DES | Estrogen-related receptor gamma | / | 0.502 | |
| 1xp9 | AIJ | Estrogen receptor | / | 0.501 | |
| 1m78 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.499 | |
| 4apu | A2K | Progesterone receptor | / | 0.499 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.499 | |
| 3bfa | 9OD | Odorant binding protein ASP1 | / | 0.498 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.497 | |
| 1j3j | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.495 | |
| 2hw2 | RFP | Rifampin ADP-ribosyl transferase | / | 0.495 | |
| 3qly | 55V | Uncharacterized protein | / | 0.495 | |
| 1ezv | SMA | Cytochrome b | / | 0.494 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.494 | |
| 2xvw | 9NR | Serum albumin | / | 0.494 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.494 | |
| 1u3q | 272 | Estrogen receptor beta | / | 0.493 | |
| 2bxq | IMN | Serum albumin | / | 0.493 | |
| 3jsu | KA5 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.493 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.492 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.491 | |
| 2oax | SNL | Mineralocorticoid receptor | / | 0.491 | |
| 3h1j | SMA | Cytochrome b | / | 0.491 | |
| 3ml8 | ML8 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.491 | |
| 4nkv | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.491 | |
| 1ia4 | TQ6 | Dihydrofolate reductase | 1.5.1.3 | 0.490 | |
| 1kb9 | SMA | Cytochrome b | / | 0.490 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.490 | |
| 1wvx | BD4 | Death-associated protein kinase 1 | 2.7.11.1 | 0.489 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.489 | |
| 4fjz | 4FJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.489 | |
| 4ea3 | 0NN | Nociceptin receptor | / | 0.489 | |
| 1og5 | SWF | Cytochrome P450 2C9 | / | 0.488 | |
| 2yat | EEU | Estrogen receptor | / | 0.488 | |
| 3qg2 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.488 | |
| 1rx6 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.487 | |
| 1rx8 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.486 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.486 | |
| 4iwf | 15Q | Estrogen receptor | / | 0.486 | |
| 1gwq | ZTW | Estrogen receptor | / | 0.485 | |
| 1ly3 | COG | Dihydrofolate reductase | 1.5.1.3 | 0.485 | |
| 2j7x | EST | Estrogen receptor beta | / | 0.485 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.485 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.485 | |
| 3p9t | TCL | Repressor | / | 0.485 | |
| 1l2j | ETC | Estrogen receptor beta | / | 0.484 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.484 | |
| 2hvc | LGD | Androgen receptor | / | 0.484 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.484 | |
| 4iaq | 2GM | 5-hydroxytryptamine receptor 1B | / | 0.484 | |
| 5iua | 6DX | Adenosine receptor A2a | / | 0.484 | |
| 3uza | T4G | Adenosine receptor A2a | / | 0.484 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 2blb | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.483 | |
| 3new | 3NE | Mitogen-activated protein kinase 14 | / | 0.483 | |
| 3vev | 0H4 | Glucokinase | 2.7.1.2 | 0.483 | |
| 3w5t | LHP | Vitamin D3 receptor | / | 0.483 | |
| 2xvv | 9DN | Serum albumin | / | 0.482 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.482 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.481 | |
| 2c3i | IYZ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.481 | |
| 3b9l | AZZ | Serum albumin | / | 0.481 | |
| 3bfb | 9OD | Pheromone-binding protein ASP1 | / | 0.481 | |
| 3cd2 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 3cv9 | VDX | Vitamin D3 dihydroxylase | / | 0.481 | |
| 3th8 | TH9 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.481 | |
| 4cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4jvb | 1M0 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.481 | |
| 4lm5 | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.481 | |
| 4lmu | QUE | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.481 | |
| 4wa9 | AXI | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.481 | |
| 1j3i | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.480 | |
| 2acl | REA | Retinoic acid receptor RXR-alpha | / | 0.480 | |
| 3fko | FKO | Mitogen-activated protein kinase 14 | / | 0.480 | |
| 3l71 | AZO | Cytochrome b | / | 0.480 | |
| 3vtc | TK3 | Vitamin D3 receptor | / | 0.480 | |
| 4ajw | VWN | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform | 2.7.1.153 | 0.480 | |
| 4qa1 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.480 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.479 | |
| 1zhz | ERG | Oxysterol-binding protein homolog 4 | / | 0.479 | |
| 3itz | P66 | Mitogen-activated protein kinase 14 | / | 0.479 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.479 | |
| 4n70 | 2HX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.479 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.479 | |
| 1uy8 | PU5 | Heat shock protein HSP 90-alpha | / | 0.478 | |
| 2j2i | LY4 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.478 | |
| 2o65 | MYF | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.478 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.478 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.478 | |
| 5dc5 | B3N | Histone deacetylase 8 | 3.5.1.98 | 0.478 | |
| 2fzh | DH1 | Dihydrofolate reductase | 1.5.1.3 | 0.477 | |
| 2nru | T12 | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.477 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.477 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.477 | |
| 4k18 | 1OB | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.477 | |
| 4k9y | K9Y | Focal adhesion kinase 1 | 2.7.10.2 | 0.477 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.477 | |
| 1m79 | MQ1 | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.476 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.476 | |
| 3mee | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.476 | |
| 3pm0 | BHF | Cytochrome P450 1B1 | / | 0.476 | |
| 3qlr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.476 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.476 | |
| 3sqq | 99Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.476 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 1w22 | NHB | Histone deacetylase 8 | 3.5.1.98 | 0.475 | |
| 1yye | 196 | Estrogen receptor beta | / | 0.475 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.475 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.475 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.475 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.475 | |
| 4nky | 3QZ | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.475 | |
| 4ubs | DIF | Pentalenic acid synthase | 1.14.15.11 | 0.475 | |
| 1ai9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.474 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.474 | |
| 2vzm | NRB | Cytochrome P450 monooxygenase PikC | / | 0.474 | |
| 3qgt | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.474 | |
| 3ue4 | DB8 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.474 | |
| 4jbt | ASD | Cytochrome P450 monooxygenase | / | 0.474 | |
| 4l42 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.474 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.473 | |
| 3cyz | 9OD | Pheromone-binding protein ASP1 | / | 0.473 | |
| 3d0b | SNX | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 3koo | 24D | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.473 | |
| 3zqt | TES | Androgen receptor | / | 0.473 | |
| 4h1j | 0YH | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.473 | |
| 4h3c | 0YZ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.473 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.473 | |
| 4ib4 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.473 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.472 | |
| 3ics | ADP | Coenzyme A disulfide reductase | / | 0.472 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.472 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.472 | |
| 4jda | A9S | Abscisic acid receptor PYL3 | / | 0.472 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.471 | |
| 3fy9 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.471 | |
| 3ubd | SL0 | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.471 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.471 | |
| 4k1b | 1OC | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.471 | |
| 4ysw | NAI | Xanthine dehydrogenase/oxidase | / | 0.471 | |
| 5iub | CLR | Adenosine receptor A2a | / | 0.471 | |
| 3rey | XAC | Adenosine receptor A2a | / | 0.471 | |
| 1lri | CLR | Beta-elicitin cryptogein | / | 0.470 | |
| 1osv | CHC | Bile acid receptor | / | 0.470 | |
| 1q99 | ANP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.470 | |
| 1rt4 | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 2azy | CHD | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.470 | |
| 2pul | ACP | Methylthioribose kinase | 2.7.1.100 | 0.470 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.470 | |
| 2ylq | TES | Androgen receptor | / | 0.470 | |
| 3a60 | STU | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.470 | |
| 3ans | S38 | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.470 | |
| 3be2 | RAJ | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.470 | |
| 4a9i | P9I | Bromodomain-containing protein 2 | / | 0.470 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.470 | |
| 4j6c | STR | Cytochrome P450 monooxygenase | / | 0.470 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1ia1 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 1j3k | WRA | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.469 | |
| 1m7a | MQU | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 2hl1 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.469 | |
| 2idz | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.469 | |
| 2qd5 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 2y03 | Y01 | Beta-1 adrenergic receptor | / | 0.469 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 3bgp | VX1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.469 | |
| 3eek | 53S | Uncharacterized protein | / | 0.469 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.469 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.469 | |
| 3um8 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.469 | |
| 3w1w | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.469 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.469 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.469 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.469 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.469 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2b36 | 5PP | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.468 | |
| 2ilt | NN1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.468 | |
| 2iw6 | QQ2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.468 | |
| 2uxp | CLM | HTH-type transcriptional regulator TtgR | / | 0.468 | |
| 3qlr | QLR | Dihydrofolate reductase | 1.5.1.3 | 0.468 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.468 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.468 | |
| 4r20 | AER | Cytochrome P450 family 17 polypeptide 2 | / | 0.468 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.468 | |
| 1n4h | REA | Nuclear receptor ROR-beta | / | 0.467 | |
| 1rx1 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1s6q | TPB | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 2br1 | PFP | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.467 | |
| 3d75 | NBB | Pheromone-binding protein ASP1 | / | 0.467 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 4em9 | TCE | Peroxisome proliferator-activated receptor gamma | / | 0.467 | |
| 4ig3 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 5cyq | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.467 | |
| 1d2s | DHT | Sex hormone-binding globulin | / | 0.466 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.466 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.466 | |
| 3d84 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.466 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.466 | |
| 3ntg | D72 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.466 | |
| 3sgv | 2BJ | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.466 | |
| 3tk3 | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.466 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.466 | |
| 4nb6 | 444 | Nuclear receptor ROR-gamma | / | 0.466 | |
| 4qkn | JMS | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.466 | |
| 1cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1sqn | NDR | Progesterone receptor | / | 0.465 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.465 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2jed | LG8 | Protein kinase C theta type | 2.7.11.13 | 0.465 | |
| 3pre | 3RE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.465 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.465 | |
| 4d9t | 0JG | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.465 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.465 | |
| 4jlk | 1NO | Deoxycytidine kinase | 2.7.1.74 | 0.465 | |
| 1eh4 | IC1 | Casein kinase I homolog 1 | 2.7.11.1 | 0.464 | |
| 1zga | HMK | Isoflavone 4'-O-methyltransferase | / | 0.464 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.464 | |
| 3cz0 | 9OD | Pheromone-binding protein ASP1 | / | 0.464 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.464 | |
| 4few | PP2 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.464 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.464 | |
| 4klr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 1qxl | FR8 | Adenosine deaminase | 3.5.4.4 | 0.463 | |
| 1xws | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.463 | |
| 1ywr | LI9 | Mitogen-activated protein kinase 14 | / | 0.463 | |
| 2feu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.463 | |
| 2i0e | PDS | Protein kinase C beta type | 2.7.11.13 | 0.463 | |
| 2m56 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.463 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3cxh | SMA | Cytochrome b | / | 0.463 | |
| 3h0a | 9RA | Retinoic acid receptor RXR-alpha | / | 0.463 | |
| 3lan | KBT | Gag-Pol polyprotein | 2.7.7.49 | 0.463 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.463 | |
| 3w0h | W12 | Vitamin D3 receptor | / | 0.463 | |
| 3wy0 | COA | Uncharacterized protein | / | 0.463 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.463 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.463 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.463 | |
| 1jlc | FTC | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 1ove | 358 | Mitogen-activated protein kinase 14 | / | 0.462 | |
| 1rdt | L79 | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 1rx7 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 1tkz | H16 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 1tsd | F89 | Thymidylate synthase | / | 0.462 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.462 | |
| 1xls | REA | Retinoic acid receptor RXR-alpha | / | 0.462 | |
| 2aa2 | AS4 | Mineralocorticoid receptor | / | 0.462 | |
| 2cd2 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2hqp | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.462 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 3dpd | 41A | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 3i0r | RT3 | Gag-Pol polyprotein | 2.7.7.49 | 0.462 | |
| 3oey | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.462 | |
| 3ua5 | 06X | Cytochrome P450 2B6 | 1.14.13 | 0.462 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.462 | |
| 3w0r | ANP | Hygromycin-B 4-O-kinase | 2.7.1.163 | 0.462 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.462 | |
| 4ivd | 15T | Tyrosine-protein kinase JAK1 | / | 0.462 | |
| 4ug7 | 1EV | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.462 | |
| 5ecc | NAP | Dehydrofolate reductase type I | / | 0.462 | |
| 1c1c | 612 | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 1enz | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.461 | |
| 1iyz | NDP | Probable quinone oxidoreductase | / | 0.461 | |
| 1nq7 | ARL | Nuclear receptor ROR-beta | / | 0.461 | |
| 1p44 | GEQ | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.461 | |
| 1v1k | 3FP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.461 | |
| 2aax | PDN | Mineralocorticoid receptor | / | 0.461 | |
| 2d3m | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.461 | |
| 2ic3 | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.461 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.461 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.461 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.461 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.461 | |
| 3h1v | TK1 | Glucokinase | 2.7.1.2 | 0.461 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.461 | |
| 3w5p | 4OA | Vitamin D3 receptor | / | 0.461 | |
| 4a9m | P9M | Bromodomain-containing protein 2 | / | 0.461 | |
| 4g2i | 0VQ | Vitamin D3 receptor | / | 0.461 | |
| 4h96 | 14Q | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 4hni | 16W | Casein kinase I isoform epsilon | 2.7.11.1 | 0.461 | |
| 4okb | 198 | Androgen receptor | / | 0.461 | |
| 4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.461 | |
| 5h8t | RTL | Retinol-binding protein 1 | / | 0.461 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.460 | |
| 1dr3 | TAP | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1sr7 | MOF | Progesterone receptor | / | 0.460 | |
| 2b00 | GCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.460 | |
| 2cig | 1DG | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2fzi | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 2pio | DHT | Androgen receptor | / | 0.460 | |
| 2zv2 | 609 | Calcium/calmodulin-dependent protein kinase kinase 2 | 2.7.11.17 | 0.460 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.460 | |
| 3qrt | X14 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.460 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 3vbq | 0F5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.460 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 4i8v | BHF | Cytochrome P450 1A1 | 1.14.14.1 | 0.460 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.460 | |
| 4ifv | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.460 | |
| 1bvr | THT | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 1e8w | QUE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.459 | |
| 2p1v | 5TN | Retinoic acid receptor RXR-alpha | / | 0.459 | |
| 2q59 | 240 | Peroxisome proliferator-activated receptor gamma | / | 0.459 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.459 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.459 | |
| 3bej | MUF | Bile acid receptor | / | 0.459 | |
| 3kf7 | L9G | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3l8s | BFF | Mitogen-activated protein kinase 14 | / | 0.459 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 3ns2 | PYV | Abscisic acid receptor PYL2 | / | 0.459 | |
| 3zw3 | ZW3 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 4bcq | TJF | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 4ez5 | 0RS | Cyclin-dependent kinase 6 | 2.7.11.22 | 0.459 | |
| 4fsz | HK8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.459 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.459 | |
| 1ju6 | LYA | Thymidylate synthase | 2.1.1.45 | 0.458 | |
| 1yhs | STU | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 2aqh | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 2iog | IOG | Estrogen receptor | / | 0.458 | |
| 2yhd | TES | Androgen receptor | / | 0.458 | |
| 2z97 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.458 | |
| 3akm | 11D | Fatty acid-binding protein, intestinal | / | 0.458 | |
| 3cy3 | JN5 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 3fl4 | FL4 | Mitogen-activated protein kinase 14 | / | 0.458 | |
| 3imx | B84 | Glucokinase | 2.7.1.2 | 0.458 | |
| 3jxw | LXG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.458 | |
| 3l70 | JZV | Cytochrome b | / | 0.458 | |
| 3of2 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 3v1s | 0LH | Strictosidine synthase | 4.3.3.2 | 0.458 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.458 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.458 | |
| 4f64 | 0S8 | Fibroblast growth factor receptor 1 | / | 0.458 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.458 | |
| 4neu | Q1A | Receptor-interacting serine/threonine-protein kinase 1 | 2.7.11.1 | 0.458 | |
| 4tv3 | ML9 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | / | 0.458 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.458 | |
| 1di8 | DTQ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 1jlq | SBN | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1t7t | DHT | Androgen receptor | / | 0.457 | |
| 1tvr | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.457 | |
| 1txi | TX5 | Vitamin D3 receptor | / | 0.457 | |
| 1vrw | NAI | Enoyl-ACP reductase | / | 0.457 | |
| 1wc0 | APC | Adenylate cyclase | / | 0.457 | |
| 1yi4 | ADN | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.457 | |
| 1zid | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.457 | |
| 3el7 | PD3 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.457 | |
| 3qtz | X42 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 3sgx | 0FW | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.457 | |
| 3tkh | 07S | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.457 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.457 | |
| 3wd7 | COA | Acridone synthase | / | 0.457 | |
| 4bgq | 38R | Cyclin-dependent kinase-like 5 | 2.7.11.22 | 0.457 | |
| 4dhy | S41 | Glucokinase | 2.7.1.2 | 0.457 | |
| 4ftk | H9K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.457 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4nx6 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4oha | HFT | Androgen receptor | / | 0.457 | |
| 4p6w | MOF | Glucocorticoid receptor | / | 0.457 | |
| 1aoe | GW3 | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 1kl2 | FON | Serine hydroxymethyltransferase | / | 0.456 | |
| 1mj3 | HXC | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.456 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.456 | |
| 1tl3 | H20 | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 1w2c | ANP | Inositol-trisphosphate 3-kinase A | 2.7.1.127 | 0.456 | |
| 1xjd | STU | Protein kinase C theta type | 2.7.11.13 | 0.456 | |
| 2d52 | COA | 5,7-dihydroxy-2-methylchromone synthase | 2.3.1.216 | 0.456 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.456 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.456 | |
| 2puu | G2G | Mitogen-activated protein kinase 14 | / | 0.456 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.456 | |
| 2xj1 | XJ1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 3bgz | VX3 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 3eej | 53R | Uncharacterized protein | / | 0.456 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3lam | KRP | Gag-Pol polyprotein | 2.7.7.49 | 0.456 | |
| 3wgw | T2B | Proliferating cell nuclear antigen | / | 0.456 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.456 | |
| 4at3 | LTI | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.456 | |
| 4b4o | NDP | Epimerase family protein SDR39U1 | / | 0.456 | |
| 4bcn | T9N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.456 | |
| 4dp3 | MMV | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.456 | |
| 4ia2 | BIV | Vitamin D3 receptor A | / | 0.456 | |
| 4mbl | 26L | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.456 | |
| 5k2d | ZMA | Adenosine receptor A2a | / | 0.456 | |
| 1f28 | F89 | Thymidylate synthase | 2.1.1.45 | 0.455 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.455 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.455 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.455 | |
| 1oiu | N76 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.455 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.455 | |
| 1rev | TB9 | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 1s9e | ADB | Gag-Pol polyprotein | 2.7.7.49 | 0.455 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 1xq3 | R18 | Androgen receptor | / | 0.455 | |
| 2aqi | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 2oth | NIM | Basic phospholipase A2 VRV-PL-VIIIa | 3.1.1.4 | 0.455 | |
| 2pix | DHT | Androgen receptor | / | 0.455 | |
| 2tsc | CB3 | Thymidylate synthase | / | 0.455 | |
| 2uxi | G50 | HTH-type transcriptional regulator TtgR | / | 0.455 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.455 | |
| 2ydo | ADN | Adenosine receptor A2a | / | 0.455 | |
| 3gub | GUB | Death-associated protein kinase 1 | 2.7.11.1 | 0.455 | |
| 3h18 | PMS | Esterase/lipase | / | 0.455 | |
| 3i8a | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3qlx | QLR | Uncharacterized protein | / | 0.455 | |
| 3srw | Q27 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.455 | |
| 4f1s | F1S | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
| 4h97 | 53S | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 4okx | 198 | Androgen receptor | / | 0.455 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.455 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.455 | |
| 4uhr | NGI | Adenosine receptor A2a | / | 0.455 | |
| 1dz8 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 1ee0 | CAA | 2-pyrone synthase | / | 0.454 | |
| 1eny | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 1h1s | 4SP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.454 | |
| 1ia1 | TQ3 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1vru | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.454 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 2cdz | 23D | Serine/threonine-protein kinase PAK 4 | 2.7.11.1 | 0.454 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.454 | |
| 2ydv | NEC | Adenosine receptor A2a | / | 0.454 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.454 | |
| 2zza | FOL | Dihydrofolate reductase | / | 0.454 | |
| 3bqd | DAY | Glucocorticoid receptor | / | 0.454 | |
| 3d78 | NBB | Pheromone-binding protein ASP1 | / | 0.454 | |
| 3hl7 | I47 | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 4a9e | 3PF | Bromodomain-containing protein 2 | / | 0.454 | |
| 4akn | S5B | Bromodomain-containing protein 2 | / | 0.454 | |
| 4bqp | VMY | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.454 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.454 | |
| 4fsy | HK7 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 4h98 | 14Q | Uncharacterized protein | / | 0.454 | |
| 4ie5 | MD6 | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.454 | |
| 4l4c | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.454 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.454 | |
| 1dyr | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 1hpz | AAP | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.453 | |
| 1ogu | ST8 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.453 | |
| 1qpj | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.453 | |
| 1suo | CPZ | Cytochrome P450 2B4 | 1.14.14.1 | 0.453 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.453 | |
| 1zar | ADP | RIO-type serine/threonine-protein kinase Rio2 | 2.7.11.1 | 0.453 | |
| 1zhw | HC2 | Oxysterol-binding protein homolog 4 | / | 0.453 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.453 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 2hnz | PC0 | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.453 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.453 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.453 | |
| 2vd5 | BI8 | Myotonin-protein kinase | 2.7.11.1 | 0.453 | |
| 2vf0 | F89 | Thymidylate synthase | / | 0.453 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.453 | |
| 3ddw | 055 | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.453 | |
| 3irn | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3kb0 | A8S | Abscisic acid receptor PYL2 | / | 0.453 | |
| 4a7c | E46 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.453 | |
| 4aql | TXC | Guanine deaminase | 3.5.4.3 | 0.453 | |
| 4dsc | A8S | Abscisic acid receptor PYL3 | / | 0.453 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.453 | |
| 4ezk | 0SD | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4fad | 0TB | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4feq | 0T8 | Tyrosine-protein kinase receptor TYRO3 | 2.7.10.1 | 0.453 | |
| 4fl1 | ANP | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.453 | |
| 4fob | 0US | ALK tyrosine kinase receptor | 2.7.10.1 | 0.453 | |
| 4iwv | 1J9 | Glucokinase | 2.7.1.2 | 0.453 | |
| 4y8w | STR | Steroid 21-hydroxylase | / | 0.453 | |
| 5cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 1h1p | CMG | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.452 | |
| 1ke6 | LS2 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1kv2 | B96 | Mitogen-activated protein kinase 14 | / | 0.452 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.452 | |
| 1oiy | N41 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 1xiu | REA | Retinoic acid receptor RXR | / | 0.452 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 2q8s | L92 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 2x7g | PVB | SRSF protein kinase 2 | 2.7.11.1 | 0.452 | |
| 2ynf | WHU | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 3ar7 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.452 | |
| 3bgq | VX2 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.452 | |
| 3eig | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3f88 | 3HT | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.452 | |
| 3ibe | L64 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 3inv | C50 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.452 | |
| 3inw | JZB | Heat shock protein HSP 90-alpha | / | 0.452 | |
| 3med | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.452 | |
| 3ncg | BK1 | Calmodulin-domain protein kinase 1, putative | / | 0.452 | |
| 3r1s | X73 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3r6x | X84 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 3zcw | 4A2 | Kinesin-like protein KIF11 | / | 0.452 | |
| 3zux | TCH | Transporter | / | 0.452 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4bkz | 1WS | Maternal embryonic leucine zipper kinase | 2.7.11.1 | 0.452 | |
| 4bqr | IBH | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4eos | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.452 | |
| 4ftj | H8K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 4gyz | D5M | Tyrosyl-DNA phosphodiesterase 2 | 3.1.4 | 0.452 | |
| 4i22 | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.452 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.452 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.452 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1kyo | SMA | Cytochrome b | / | 0.451 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1tkx | GWB | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.451 | |
| 2bxm | IMN | Serum albumin | / | 0.451 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.451 | |
| 2jbl | SMA | Reaction center protein L chain | / | 0.451 | |
| 2wkm | PFY | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 2ze2 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3a99 | ANP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3d3e | D3E | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.451 | |
| 3dcv | 55E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 3dg8 | RJ6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.451 | |
| 3dho | B2M | Streptogramin A acetyltransferase | 2.3.1 | 0.451 | |
| 3g7f | UQ1 | Reaction center protein L chain | / | 0.451 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.451 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.451 | |
| 3meg | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 3mfs | ANP | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.451 | |
| 3qls | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 3qlw | N22 | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4b1f | KRH | Glutamate racemase | / | 0.451 | |
| 4c9o | CAM | Cytochrome P450 | / | 0.451 | |
| 4cdm | FO1 | Deoxyribodipyrimidine photolyase | / | 0.451 | |
| 4dfn | 0K1 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.451 | |
| 4enx | Z20 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 4g1q | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.451 | |
| 4gg7 | 0J8 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.451 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.451 | |
| 4gmy | 0X5 | Tyrosine-protein kinase JAK2 | / | 0.451 | |
| 4hvh | 19R | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.451 | |
| 4izy | 1J2 | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.451 | |
| 4jaq | COA | Alpha-pyrone synthesis polyketide synthase-like Pks11 | 2.3.1 | 0.451 | |
| 4jlj | 1NM | Deoxycytidine kinase | 2.7.1.74 | 0.451 | |
| 4jqe | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.451 | |
| 4jvf | 17X | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.451 | |
| 4jvm | XDI | Estrogen sulfotransferase | 2.8.2.4 | 0.451 | |
| 4kfn | 1QR | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.451 | |
| 4oac | ADP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.451 | |
| 4oj4 | DIF | Peroxisome proliferator-activated receptor gamma | / | 0.451 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.451 | |
| 4z9g | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.451 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 1h1r | 6CP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 1k74 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.450 | |
| 1ppj | SMA | Cytochrome b | / | 0.450 | |
| 1tl1 | H18 | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 1vyz | N5B | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.450 | |
| 3c4e | C4E | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.450 | |
| 3ez2 | ADP | Plasmid partition protein A | / | 0.450 | |
| 3fkn | FKN | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 3fsu | C2F | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.450 | |
| 3kjs | DQ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.450 | |
| 3m8p | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3m8q | DJZ | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3mec | 65B | Gag-Pol polyprotein | 2.7.7.49 | 0.450 | |
| 3mtl | FEF | Cyclin-dependent kinase 16 | 2.7.11.22 | 0.450 | |
| 3och | 2MX | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.450 | |
| 3ruk | AER | Steroid 17-alpha-hydroxylase/17,20 lyase | / | 0.450 | |
| 3tgu | WF3 | Cytochrome b | / | 0.450 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.450 | |
| 3w0y | DS4 | Vitamin D3 receptor | / | 0.450 | |
| 3w5r | LOA | Vitamin D3 receptor | / | 0.450 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.450 | |
| 4bch | T7Z | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.450 | |
| 4ceq | QCH | Integrase | / | 0.450 | |
| 4egn | TWO | Cytochrome P450 | / | 0.450 | |
| 4gue | QCT | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.450 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.450 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.450 | |
| 4oea | DHT | Androgen receptor | / | 0.450 | |
| 4u0m | GTP | Cyclic GMP-AMP synthase | / | 0.450 | |
| 4xey | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.450 | |
| 1chw | HXC | Chalcone synthase 2 | 2.3.1.74 | 0.449 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.449 | |
| 1e7v | LY2 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1eet | BFU | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1g4s | TPS | Thiamine-phosphate synthase | / | 0.449 | |
| 1ikw | EFZ | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.449 | |
| 1pme | SB2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.449 | |
| 1vj3 | TAB | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 2h2q | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.449 | |
| 2hxq | 373 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.449 | |
| 2j0j | 4ST | Focal adhesion kinase 1 | 2.7.10.2 | 0.449 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.449 | |
| 2pit | DHT | Androgen receptor | / | 0.449 | |
| 2pkl | DHT | Androgen receptor | / | 0.449 | |
| 2qbl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.449 | |
| 2qk8 | MTX | Dihydrofolate reductase | / | 0.449 | |
| 2wgj | VGH | Hepatocyte growth factor receptor | 2.7.10.1 | 0.449 | |
| 2ylo | TES | Androgen receptor | / | 0.449 | |
| 3eel | 53T | Uncharacterized protein | / | 0.449 | |
| 3fmk | FMK | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3hv7 | 1AU | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3ijd | C2F | Methylenetetrahydrofolate reductase | / | 0.449 | |
| 3jw5 | TOP | Dihydrofolate reductase | / | 0.449 | |
| 3k3j | F4C | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.449 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.449 | |
| 3p5k | P5K | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 3tuc | FPW | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.449 | |
| 4cfn | JYM | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4erw | STU | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 4fgh | 0U6 | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 4h4m | 494 | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 4hy6 | FJ1 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 4i2q | 1BT | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 4n6z | 2HW | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.449 | |
| 4olm | 198 | Androgen receptor | / | 0.449 | |
| 4yt5 | H4M | H(2)-forming methylenetetrahydromethanopterin dehydrogenase-related protein MJ1338 | / | 0.449 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.449 | |
| 5ccc | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 5dhg | DGV | Nociceptin receptor | / | 0.449 | |
| 1fm6 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.448 | |
| 1ia2 | TQ4 | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1ie4 | T44 | Transthyretin | / | 0.448 | |
| 1phe | PIY | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1rx4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1xow | R18 | Androgen receptor | / | 0.448 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.448 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.448 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.448 | |
| 2q7i | TES | Androgen receptor | / | 0.448 | |
| 2uzh | IPE | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.448 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.448 | |
| 3a4p | DFQ | Hepatocyte growth factor receptor | 2.7.10.1 | 0.448 | |
| 3aba | FLI | Cytochrome P450 | / | 0.448 | |
| 3ar5 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.448 | |
| 3d57 | 4HY | Thyroid hormone receptor beta | / | 0.448 | |
| 3el8 | PD5 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 3et7 | 349 | Protein-tyrosine kinase 2-beta | 2.7.10.2 | 0.448 | |
| 3fln | 3FN | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3hub | 469 | Mitogen-activated protein kinase 14 | / | 0.448 | |
| 3iro | 2CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3kyt | HC2 | Nuclear receptor ROR-gamma | / | 0.448 | |
| 3qar | QAR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.448 | |
| 3uow | XMP | GMP synthase [glutamine-hydrolyzing] | / | 0.448 | |
| 3vg9 | ZMA | Adenosine receptor A2a | / | 0.448 | |
| 3zep | 1NX | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.448 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 4nmb | FAD | Bifunctional protein PutA | / | 0.448 | |
| 4pkl | 1GH | Uncharacterized protein | / | 0.448 | |
| 4u97 | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.448 | |
| 5auw | QUE | Death-associated protein kinase 1 | 2.7.11.1 | 0.448 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.448 | |
| 4k5y | 1Q5 | Corticotropin-releasing factor receptor 1 | / | 0.448 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1bvr | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.447 | |
| 1dub | CAA | Enoyl-CoA hydratase, mitochondrial | 4.2.1.17 | 0.447 | |
| 1jla | TNK | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 1m78 | CLZ | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1pp9 | SMA | Cytochrome b | / | 0.447 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.447 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 1rt1 | MKC | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2e9d | B76 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.447 | |
| 2jfz | 003 | Glutamate racemase | / | 0.447 | |
| 2q7k | TES | Androgen receptor | / | 0.447 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 2zyb | KSL | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.447 | |
| 3bjh | NBB | Odorant binding protein ASP1 | / | 0.447 | |
| 3dle | GFA | Gag-Pol polyprotein | 2.7.7.49 | 0.447 | |
| 3hbb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.447 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3qlz | QLZ | Uncharacterized protein | / | 0.447 | |
| 3tub | FPU | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.447 | |
| 3v49 | PK0 | Androgen receptor | / | 0.447 | |
| 3w1f | 1O5 | Dual specificity protein kinase TTK | 2.7.12.1 | 0.447 | |
| 4boe | CLR | Japanin | / | 0.447 | |
| 4dk5 | 0KO | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.447 | |
| 4hxs | 1A3 | Bromodomain-containing protein 4 | / | 0.447 | |
| 4k4j | 1O8 | Retinoic acid receptor RXR-alpha | / | 0.447 | |
| 4nks | 2M2 | Fibroblast growth factor receptor 1 | / | 0.447 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.447 | |
| 4oed | DHT | Androgen receptor | / | 0.447 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 6prc | CEB | Reaction center protein L chain | / | 0.447 | |
| 5uvi | ZMA | Adenosine receptor A2a | / | 0.447 | |
| 1c1b | GCA | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.446 | |
| 1oi9 | N20 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 1s0x | C3S | Nuclear receptor ROR-alpha | / | 0.446 | |
| 1s1t | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 1v7a | FRC | Adenosine deaminase | 3.5.4.4 | 0.446 | |
| 1x09 | IPE | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 2a4z | BYM | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.446 | |
| 2e9c | B75 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.446 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2w3v | TOP | Dihydrofolate reductase | / | 0.446 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.446 | |
| 3cs8 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.446 | |
| 3cxw | 7CP | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3frd | DHF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3jy0 | LYG | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.446 | |
| 3k47 | D09 | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3lj3 | WYE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3oom | 507 | Activin receptor type-1 | 2.7.11.30 | 0.446 | |
| 3p79 | P79 | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3qfx | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.446 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.446 | |
| 3sls | 77D | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 4fsr | HKC | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 4g21 | 0VP | Vitamin D3 receptor A | / | 0.446 | |
| 4k7a | DHT | Androgen receptor | / | 0.446 | |
| 4l45 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.446 | |
| 4mfb | 29T | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 4q5h | ANP | Protein kinase OspG | 2.7 | 0.446 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.446 | |
| 6cox | S58 | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.446 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1bq6 | COA | Chalcone synthase 2 | 2.3.1.74 | 0.445 | |
| 1e8x | ATP | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 1hni | AAA | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1pxx | DIF | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 1szm | BI4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 1uhl | MEI | Retinoic acid receptor RXR-beta | / | 0.445 | |
| 1y60 | H4M | 5,6,7,8-tetrahydromethanopterin hydro-lyase | 4.2.1.147 | 0.445 | |
| 1ysx | 4EB | Serum albumin | / | 0.445 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.445 | |
| 2blc | CP7 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.445 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2e9o | A58 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.445 | |
| 2gcd | STU | Serine/threonine-protein kinase TAO2 | 2.7.11.1 | 0.445 | |
| 2i4j | DRJ | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.445 | |
| 2om9 | AJA | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2yfe | YFE | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 2ylp | TES | Androgen receptor | / | 0.445 | |
| 3bhe | BZN | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 3ctj | 320 | Hepatocyte growth factor receptor | 2.7.10.1 | 0.445 | |
| 3dt1 | P40 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3gi3 | B10 | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.445 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.445 | |
| 3ia4 | MTX | Dihydrofolate reductase | / | 0.445 | |
| 3ict | ADP | Coenzyme A disulfide reductase | / | 0.445 | |
| 3igo | ANP | Calmodulin-domain protein kinase 1, putative | / | 0.445 | |
| 3oez | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.445 | |
| 3qru | X19 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 3sgy | 06W | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.445 | |
| 3u4u | LNH | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 3uix | Q17 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3x04 | GNP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.445 | |
| 4bdd | Z0O | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.445 | |
| 4ds8 | A8S | Abscisic acid receptor PYL3 | / | 0.445 | |
| 4eoi | 1RO | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.445 | |
| 4fa6 | 0TA | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4kl9 | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 4o2b | LOC | Tubulin beta-2B chain | / | 0.445 | |
| 4pda | CTN | Nucleoside permease | / | 0.445 | |
| 4r8q | ADP | Mitotic checkpoint serine/threonine-protein kinase BUB1 | 2.7.11.1 | 0.445 | |
| 5akk | 1P8 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.445 | |
| 5aux | KMP | Death-associated protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1ke9 | LS5 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1yol | S03 | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.444 | |
| 2ban | 357 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 2bhe | BRY | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2g2h | P16 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.444 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.444 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2p1u | 4TN | Retinoic acid receptor RXR-alpha | / | 0.444 | |
| 2q70 | DC8 | Estrogen receptor | / | 0.444 | |
| 3aox | EMH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
| 3cx5 | SMA | Cytochrome b | / | 0.444 | |
| 3dds | 26B | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.444 | |
| 3dmj | GWE | Pol protein | / | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta | / | 0.444 | |
| 3dxj | NE6 | DNA-directed RNA polymerase subunit beta' | / | 0.444 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.444 | |
| 3id8 | MRK | Glucokinase | 2.7.1.2 | 0.444 | |
| 3ig7 | EFP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3jw3 | TOP | Dihydrofolate reductase | / | 0.444 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.444 | |
| 3n61 | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.444 | |
| 3pt6 | SAH | DNA (cytosine-5)-methyltransferase 1 | 2.1.1.37 | 0.444 | |
| 3r3b | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.444 | |
| 3td8 | D2R | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.444 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.444 | |
| 3vs7 | KS1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.444 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.444 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.444 | |
| 4bcp | T3C | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 4fex | 0TO | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.444 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.444 | |
| 4ftc | H6K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 4g20 | 484 | Vitamin D3 receptor A | / | 0.444 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.444 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.444 | |
| 4ixf | IXF | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.444 | |
| 4lvb | 20N | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.444 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4mvf | STU | Calcium-dependent protein kinase 2 | 2.7.11.1 | 0.444 | |
| 4py6 | R78 | Bromodomain protein, putative | / | 0.444 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.444 | |
| 5cu6 | ATP | Casein kinase II subunit alpha | 2.7.11.1 | 0.444 | |
| 3rfm | CFF | Adenosine receptor A2a | / | 0.444 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.443 | |
| 1dyi | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1jio | DEB | 6-deoxyerythronolide B hydroxylase | / | 0.443 | |
| 1ly4 | COQ | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1prc | UQ1 | Reaction center protein L chain | / | 0.443 | |
| 1r9o | FLP | Cytochrome P450 2C9 | / | 0.443 | |
| 1t86 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2hl0 | A3S | Threonine--tRNA ligase | 6.1.1.3 | 0.443 | |
| 2hxl | 422 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 2pwl | ACP | Fibroblast growth factor receptor 2 | / | 0.443 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3a3y | OBN | Sodium/potassium-transporting ATPase subunit alpha | / | 0.443 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 3fls | FLS | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3h4v | NAP | Pteridine reductase 1 | 1.5.1.33 | 0.443 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 3l1s | Z92 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 3lfn | A27 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 3q0g | BCO | Probable enoyl-CoA hydratase echA8 | 4.2.1.17 | 0.443 | |
| 3rmf | 20Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.443 | |
| 3sa2 | 7DR | Dihydrofolate reductase | / | 0.443 | |
| 3sai | 9DR | Dihydrofolate reductase | / | 0.443 | |
| 3sx2 | NAD | Uncharacterized protein | / | 0.443 | |
| 3v4a | PK1 | Androgen receptor | / | 0.443 | |
| 3vf9 | 477 | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.443 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.443 | |
| 3we4 | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.443 | |
| 4afj | SJJ | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4dtk | 7LI | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4ejh | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.443 | |
| 4enh | FVX | Cholesterol 24-hydroxylase | / | 0.443 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.443 | |
| 4fsw | HK6 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.443 | |
| 4h4u | NDP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4i41 | MIX | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 4im2 | BX7 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.443 | |
| 4nm0 | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.443 | |
| 4ogr | ADN | Cyclin-dependent kinase 9 | 2.7.11.22 | 0.443 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4ug7 | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.443 | |
| 4uga | H4B | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.443 | |
| 1dz4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1e3v | DXC | Steroid Delta-isomerase | 5.3.3.1 | 0.442 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.442 | |
| 1fby | REA | Retinoic acid receptor RXR-alpha | / | 0.442 | |
| 1fdw | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.442 | |
| 1fml | RTL | Retinol dehydratase | / | 0.442 | |
| 1i7i | AZ2 | Peroxisome proliferator-activated receptor gamma | / | 0.442 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.442 | |
| 1phg | MYT | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.442 | |
| 1s1w | UC1 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 1t65 | DHT | Androgen receptor | / | 0.442 | |
| 2aqk | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.442 | |
| 2bts | U32 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 2hog | 710 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 2j4z | 626 | Aurora kinase A | 2.7.11.1 | 0.442 | |
| 2l98 | STL | Troponin C, slow skeletal and cardiac muscles | / | 0.442 | |
| 2rf2 | MRX | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 2uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.442 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 3clb | TMQ | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3fnf | JPM | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 3fy8 | XCF | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.442 | |
| 3i0s | RT7 | Gag-Pol polyprotein | 2.7.7.49 | 0.442 | |
| 3poz | 03P | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 3q9z | TXQ | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3qls | 55V | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 3qwk | X62 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3r7e | X88 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3roy | 22Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.442 | |
| 3tea | 4CO | 4-hydroxybenzoyl-CoA thioesterase | 3.1.2.23 | 0.442 | |
| 3uvq | FS8 | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.442 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.442 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4ft9 | H4K | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 4g2h | 0VQ | Vitamin D3 receptor A | / | 0.442 | |
| 4gii | 0X6 | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.442 | |
| 4grb | 0XG | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.442 | |
| 4iae | 1DX | Alr2278 protein | / | 0.442 | |
| 4kjj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4kne | 1CY | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 4l49 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1bif | AGS | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.441 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.441 | |
| 1e9h | INR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 1fm9 | 9CR | Retinoic acid receptor RXR-alpha | / | 0.441 | |
| 1rt5 | UC2 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 1tdu | DUR | Thymidylate synthase | / | 0.441 | |
| 1tkt | H12 | Gag-Pol polyprotein | 2.7.7.49 | 0.441 | |
| 2ayp | 43A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2vuw | 5ID | Serine/threonine-protein kinase haspin | 2.7.11.1 | 0.441 | |
| 2x1n | X1N | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 2xvd | AS6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2y30 | SM8 | Putative repressor SimReg2 | / | 0.441 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 3ckx | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 3cnj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.441 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3eem | 53V | Uncharacterized protein | / | 0.441 | |
| 3ekx | 1UN | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3gob | HXX | DdmC | / | 0.441 | |
| 3iqz | H4M | F420-dependent methylenetetrahydromethanopterin dehydrogenase | 1.5.98.1 | 0.441 | |
| 3jpv | 1DR | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 3juq | AJD | Phenazine biosynthesis protein A/B | / | 0.441 | |
| 3jwm | 5WB | Dihydrofolate reductase | / | 0.441 | |
| 3l63 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 3o0g | 3O0 | Cyclin-dependent-like kinase 5 | 2.7.11.1 | 0.441 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.441 | |
| 3rm7 | 19Z | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 3saz | 043 | Malate synthase G | / | 0.441 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.441 | |
| 3tmz | 06X | Cytochrome P450 2B4 | 1.14.14.1 | 0.441 | |
| 3wrl | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4acc | 7YG | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 4awo | 99B | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 4bhz | Z0B | Dual specificity protein kinase TTK | 2.7.12.1 | 0.441 | |
| 4bqu | CLR | Japanin | / | 0.441 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.441 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4ewq | MWL | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4iwo | 1H4 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4k0y | 1OA | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.441 | |
| 4lts | LTS | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 4oav | ACP | 2-5A-dependent ribonuclease | 3.1.26 | 0.441 | |
| 4qmn | DB8 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4qmp | DKI | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.441 | |
| 4rkd | KET | Aminotransferase | / | 0.441 | |
| 4yzc | STU | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.441 | |
| 4zth | GG5 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.440 | |
| 1i58 | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.440 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1q8w | M77 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.440 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.440 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 1x2h | LPA | Lipoate-protein ligase A | 6.3.1.20 | 0.440 | |
| 1x7h | NDP | Putative ketoacyl reductase | 1.3.1 | 0.440 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 2bbq | PFG | Thymidylate synthase | / | 0.440 | |
| 2bx8 | AZQ | Serum albumin | / | 0.440 | |
| 2cpp | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 2duv | 371 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
| 2puj | HPZ | 2-hydroxy-6-oxo-6-phenylhexa-2,4-dienoate hydrolase | 3.7.1.8 | 0.440 | |
| 2qjy | SMA | Cytochrome b | / | 0.440 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.440 | |
| 2w3a | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 2zaw | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 3fc6 | REA | Retinoic acid receptor RXR-alpha | / | 0.440 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3ipq | 965 | Oxysterols receptor LXR-alpha | / | 0.440 | |
| 3nbp | JGZ | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 3nny | 59R | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
| 4ach | KDI | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.440 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4cd0 | AWJ | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 4dij | BLF | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.440 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.440 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.440 | |
| 4eqw | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 4fod | 0UV | ALK tyrosine kinase receptor | 2.7.10.1 | 0.440 | |
| 4fz6 | 0VG | Tyrosine-protein kinase SYK | 2.7.10.2 | 0.440 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4gkh | 0J9 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.440 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.440 | |
| 4jv8 | 1M1 | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.440 | |
| 4kba | 1QM | Casein kinase I isoform delta | 2.7.11.1 | 0.440 | |
| 4ko0 | JLJ | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.440 | |
| 4l3l | 5FI | Ribosomal protein S6 kinase beta-1 | 2.7.11.1 | 0.440 | |
| 4l9q | 9TP | Serum albumin | / | 0.440 | |
| 4o71 | CPB | Bromodomain-containing protein 4 | / | 0.440 | |
| 4ofr | DHT | Androgen receptor | / | 0.440 | |
| 4qmy | STU | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.440 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.440 | |
| 4uga | Q05 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.440 | |
| 4xe6 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4ylh | YE1 | (3,5-dihydroxyphenyl)acetyl-CoA 1,2-dioxygenase | / | 0.440 | |
| 5djt | FMN | NPH1-2 | / | 0.440 | |
| 6gsw | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.440 |