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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5dsg0HKMuscarinic acetylcholine receptor M4

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
5dsg0HKMuscarinic acetylcholine receptor M4/1.000
5cxv0HKMuscarinic acetylcholine receptor M1/0.633
4u163C0Muscarinic acetylcholine receptor M3/0.632
4daj0HKMuscarinic acetylcholine receptor M3/0.599
4u140HKMuscarinic acetylcholine receptor M3/0.588
3uonQNBMuscarinic acetylcholine receptor M2/0.573
3uzxAOM3-oxo-5-beta-steroid 4-dehydrogenase/0.533
4u150HKMuscarinic acetylcholine receptor M3/0.530
4rn615UProthrombin3.4.21.50.521
3uzzTES3-oxo-5-beta-steroid 4-dehydrogenase/0.519
1w6jR71Lanosterol synthase5.4.99.70.518
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.508
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.507
4hcy0YNTransketolase/0.506
2zhf49UProthrombin3.4.21.50.502
2vqqTFGHistone deacetylase 43.5.1.980.498
1rxjBNIStreptavidin/0.497
1t40ID5Aldose reductase1.1.1.210.497
4j7hTRHPCZA361.3/0.497
1qv0CZHObelin/0.496
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.495
2wzySQXSoluble acetylcholine receptor/0.495
3ho9N3A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.493
4isg1FYGlucokinase2.7.1.20.493
1qv1CZHObelin/0.492
4bvhOCZNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.492
4jq3ZOMAldo-keto reductase family 1 member C2/0.492
2ipiAKYAclacinomycin-N/aclacinomycin-A oxidase/0.491
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.491
3nwlNDPCatalase1.11.1.60.491
3c1oNAPEugenol synthase/0.489
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.489
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.489
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.488
2zevIPEGeranylgeranyl pyrophosphate synthase/0.487
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.487
4dbs0HVAldo-keto reductase family 1 member C3/0.487
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.487
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.487
1akcPPEAspartate aminotransferase, mitochondrial2.6.1.10.486
1rzuADPGlycogen synthase 12.4.1.210.486
3casASD3-oxo-5-beta-steroid 4-dehydrogenase/0.486
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.485
2uxoTACHTH-type transcriptional regulator TtgR/0.485
3uzzASD3-oxo-5-beta-steroid 4-dehydrogenase/0.485
4xbjIN5Alanine racemase, biosynthetic/0.485
5c1mCLRMu-type opioid receptor/0.485
1jf2CZHObelin/0.484
1s36CEIObelin/0.484
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.484
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.484
4e2yJHZMethyltransferase/0.484
1vkgCRIHistone deacetylase 83.5.1.980.483
3aosJH2Hemolymph juvenile hormone binding protein/0.483
3h3t16HCollagen type IV alpha-3-binding protein/0.483
3hiiPNTAmiloride-sensitive amine oxidase [copper-containing]/0.483
4b117I1Glycylpeptide N-tetradecanoyltransferase/0.483
1b2lNDCAlcohol dehydrogenase1.1.1.10.482
1ry0PG2Aldo-keto reductase family 1 member C3/0.482
1ycgFMNNitric oxide reductase10.482
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.482
8catNDPCatalase1.11.1.60.482
1kyvRBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.481
2qjpANJCytochrome b/0.481
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.481
3iu9T07Methionine aminopeptidase 2/0.481
4i5xFLFAldo-keto reductase family 1 member B101.1.10.481
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.480
3vo2FADFerredoxin--NADP reductase/0.480
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.479
4bfxZVXPantothenate kinase2.7.1.330.479
4epq0RRPoly(ADP-ribose) glycohydrolase/0.479
5liu388Aldo-keto reductase family 1 member B101.1.10.479
5stdUNNScytalone dehydratase4.2.1.940.479
4mqt2CUMuscarinic acetylcholine receptor M2/0.479
1d3dBZTProthrombin3.4.21.50.478
1pj7FFODimethylglycine oxidase1.5.3.100.478
1xm1GAHProthrombin3.4.21.50.478
3h3r14HCollagen type IV alpha-3-binding protein/0.478
4bfzZVZPantothenate kinase2.7.1.330.478
4i6gFADCryptochrome-2/0.478
4isf1FXGlucokinase2.7.1.20.478
4jln18VDeoxycytidine kinase2.7.1.740.478
4jtrIBPAldo-keto reductase family 1 member C2/0.478
1ieiZESAldose reductase1.1.1.210.477
1ny2ARG_PRO_PRO_GLYProthrombin3.4.21.50.477
4glx0XSDNA ligase6.5.1.20.477
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.477
1p0pBCHCholinesterase3.1.1.80.476
1re0AFBADP-ribosylation factor 1/0.476
1re0AFBARF guanine-nucleotide exchange factor 1/0.476
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.476
2f3815MAldo-keto reductase family 1 member C3/0.476
3biu10UProthrombin3.4.21.50.476
3fsjD7KBenzoylformate decarboxylase4.1.1.70.476
3uyk0CXProbable NDP-rhamnosyltransferase/0.476
4bfuZVUPantothenate kinase2.7.1.330.476
1aquESTEstrogen sulfotransferase, testis isoform2.8.2.40.475
2fjm073Tyrosine-protein phosphatase non-receptor type 13.1.3.480.475
2z4w749Geranylgeranyl pyrophosphate synthase/0.475
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.475
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.475
1zgbA1EAcetylcholinesterase3.1.1.70.474
1zq5E04Aldo-keto reductase family 1 member C3/0.474
2zc922UProthrombin3.4.21.50.474
2zda32UProthrombin3.4.21.50.474
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.474
4uugPXGBranched-chain amino acid aminotransferase, putative/0.474
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.473
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.473
2zdv37UProthrombin3.4.21.50.473
4b12C23Glycylpeptide N-tetradecanoyltransferase/0.473
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.473
4j7gTRHPCZA361.3/0.473
4jvmXDIEstrogen sulfotransferase2.8.2.40.473
1jdzFMBPurine nucleoside phosphorylase/0.472
1pj6FOLDimethylglycine oxidase1.5.3.100.472
1rvvINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.472
2zgx29UProthrombin3.4.21.50.472
4a2zVIQGlycylpeptide N-tetradecanoyltransferase/0.472
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.472
4bfwZVWPantothenate kinase2.7.1.330.472
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.472
2ycxP32Beta-1 adrenergic receptor/0.472
1dibL34C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.471
1g63FMNEpidermin decarboxylase4.1.10.471
1obnASVIsopenicillin N synthase1.21.3.10.471
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.471
2vdyHCYCorticosteroid-binding globulin/0.471
2vqoTFGHistone deacetylase 43.5.1.980.471
3cv6HXSAldo-keto reductase family 1 member C21/0.471
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.471
3h3qH13Collagen type IV alpha-3-binding protein/0.471
3u57DH8Raucaffricine-O-beta-D-glucosidase3.2.1.1250.471
3ug8IMNAldo-keto reductase family 1 member C3/0.471
1lkeDOGBilin-binding protein/0.470
1lnmDTXBilin-binding protein/0.470
2anmCDOProthrombin3.4.21.50.470
2pksG44Prothrombin3.4.21.50.470
2zhq27UProthrombin3.4.21.50.470
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.470
3q9bB3NAcetylpolyamine amidohydrolase/0.470
4ba5PXGProbable aminotransferase/0.470
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.470
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.470
4ise1FWGlucokinase2.7.1.20.470
4stdBFSScytalone dehydratase4.2.1.940.470
2zi224UProthrombin3.4.21.50.469
4ia05BBcGMP-specific 3',5'-cyclic phosphodiesterase/0.469
4m4821BSodium-dependent dopamine transporter/0.469
4mrxCZHObelin/0.469
5d0rB1TAdenylate cyclase type 10/0.469
1dghNDPCatalase1.11.1.60.468
1djqFMNTrimethylamine dehydrogenase1.5.8.20.468
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
1sm4FADFerredoxin--NADP reductase/0.468
1thnADPAnti-sigma F factor/0.468
1u0wSTLChalcone synthase 22.3.1.740.468
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.468
2gevCOKPantothenate kinase2.7.1.330.468
2pncCLUPrimary amine oxidase, liver isozyme/0.468
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.468
3jyoNADQuinate/shikimate dehydrogenase (NAD(+))/0.468
3nxtD2EDihydrofolate reductase1.5.1.30.468
4dz5NAPAldo-keto reductase family 1 member C3/0.468
4fam0SZAldo-keto reductase family 1 member C3/0.468
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.467
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.467
1v08NTZ4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.467
2ay3MPPAromatic-amino-acid aminotransferase2.6.1.570.467
2zhw12UProthrombin3.4.21.50.467
4jq2SUZAldo-keto reductase family 1 member C2/0.467
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.467
1bx1FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.466
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.466
1r8qAFBCytohesin-2/0.466
1r8qAFBADP-ribosylation factor 1/0.466
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3h3sH15Collagen type IV alpha-3-binding protein/0.466
3htjETEbrA repressor/0.466
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
3zj7C1KStrictosidine-O-beta-D-glucosidase3.2.1.1050.466
4jtrIZPAldo-keto reductase family 1 member C2/0.466
4l5b1UXDeoxycytidine kinase2.7.1.740.466
4n1fCZHObelin/0.466
4n3l2FNProthrombin3.4.21.50.466
4qa0SHHHistone deacetylase 83.5.1.980.466
4rxqDUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.466
1bx0FADFerredoxin--NADP reductase, chloroplastic1.18.1.20.465
1ygjRMCPyridoxal kinase2.7.1.350.465
1z3n3NAAldose reductase1.1.1.210.465
2aouCQAHistamine N-methyltransferase2.1.1.80.465
2cekN8TAcetylcholinesterase3.1.1.70.465
2h42VIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.465
2jh6894Prothrombin3.4.21.50.465
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.465
3fhxPXLPyridoxal kinase2.7.1.350.465
3mesPT3Putative choline kinase/0.465
1dgbNDPCatalase1.11.1.60.464
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.464
3c1kT15Prothrombin3.4.21.50.464
3c4hDRLPoly [ADP-ribose] polymerase 32.4.2.300.464
3eon341Glutaryl-CoA dehydrogenase/0.464
3f3y4OABile salt sulfotransferase2.8.2.140.464
7catNDPCatalase1.11.1.60.464
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.463
1ta6177Prothrombin3.4.21.50.463
1xf0ASDAldo-keto reductase family 1 member C3/0.463
2alyYSAPhenylalanine--tRNA ligase alpha subunit6.1.1.200.463
2xnvVU3Soluble acetylcholine receptor/0.463
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.463
3c3xNAPEugenol synthase 11.1.1.3180.463
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.463
3u8fFGMRibosome inactivating protein/0.463
3wqmB29Diterpene synthase3.1.7.80.463
3zc3FADFerredoxin--NADP reductase1.18.1.20.463
4a322CDGlycylpeptide N-tetradecanoyltransferase/0.463
1kyyINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.462
1x2eATXProline iminopeptidase3.4.11.50.462
2xi4AFTAcetylcholinesterase3.1.1.70.462
2zhe13UProthrombin3.4.21.50.462
5jr34MUCarminomycin 4-O-methyltransferase DnrK2.1.1.2920.462
1g3mPCQEstrogen sulfotransferase2.8.2.40.461
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.461
1q6nP90Tyrosine-protein phosphatase non-receptor type 13.1.3.480.461
1s1rNAPAldo-keto reductase family 1 member C3/0.461
1umaIN2Prothrombin3.4.21.50.461
2aot2PMHistamine N-methyltransferase2.1.1.80.461
2iki388Aldose reductase1.1.1.210.461
2w4qCBWProstaglandin reductase 21.3.1.480.461
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.461
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.461
4c5oFADPutative monooxygenase/0.461
4da50H7Choline kinase alpha2.7.1.320.461
4jlm1NNDeoxycytidine kinase2.7.1.740.461
4lcw1VYMajor histocompatibility complex class I-related gene protein/0.461
5a4vQUEGlutathione S-transferase F22.5.1.180.461
1qiqACCIsopenicillin N synthase1.21.3.10.460
1toiHCIAspartate aminotransferase2.6.1.10.460
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
2hzqSTRApolipoprotein D/0.460
2ipjFFAAldo-keto reductase family 1 member C2/0.460
2wsa646Glycylpeptide N-tetradecanoyltransferase/0.460
3ai0PNWBeta-glucosidase/0.460
3n3bFMNProtein NrdI/0.460
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3uweVJJAldo-keto reductase family 1 member C3/0.460
4bb3KKAIsopenicillin N synthase1.21.3.10.460
4fa30SLAldo-keto reductase family 1 member C3/0.460
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
4i9z5BAcGMP-specific 3',5'-cyclic phosphodiesterase/0.460
4jtqFLPAldo-keto reductase family 1 member C2/0.460
4wevSUZAldo-keto reductase family 1 member B101.1.10.460
1c4vIH2Prothrombin3.4.21.50.459
1d3pBT3Prothrombin3.4.21.50.459
1efyBZCPoly [ADP-ribose] polymerase 12.4.2.300.459
1giqNAIIota toxin component Ia/0.459
1h8hADPATP synthase subunit alpha, mitochondrial/0.459
1h8hADPATP synthase subunit beta, mitochondrial3.6.3.140.459
1xorZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.459
1ypeUIPProthrombin3.4.21.50.459
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.459
2belCBOCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.459
2bu5TF1[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.459
2e93B29Geranylgeranyl pyrophosphate synthase/0.459
3ghsLDTAldose reductase1.1.1.210.459
3lm4HPXCatechol 2,3-dioxygenase/0.459
3zj6VM2Raucaffricine-O-beta-D-glucosidase3.2.1.1250.459
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
4gdpFADPolyamine oxidase FMS1/0.459
4jsr1NQNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.459
4ky404JBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.459
4psbGA3Cytokinin-specific binding protein/0.459
1dr3HBIDihydrofolate reductase1.5.1.30.458
1gaqFADFerredoxin/0.458
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.458
2geuCOKPantothenate kinase2.7.1.330.458
2inzOHPAldose reductase1.1.1.210.458
2qx7NAPEugenol synthase 11.1.1.3180.458
2v0mKLNCytochrome P450 3A4/0.458
3dr7GPDGDP-perosamine synthase/0.458
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3g4kROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
3nu03TUDihydrofolate reductase1.5.1.30.458
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
4dbw511Aldo-keto reductase family 1 member C3/0.458
4h6pFMNChromate reductase/0.458
4jqaID8Aldo-keto reductase family 1 member C2/0.458
4xbfFADLysine-specific histone demethylase 1A10.458
1dgfNDPCatalase1.11.1.60.457
1u65CP0Acetylcholinesterase3.1.1.70.457
1xh8R55cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.457
2bu9HFVIsopenicillin N synthase1.21.3.10.457
2cf9348Prothrombin3.4.21.50.457
2wo7ASVIsopenicillin N synthase1.21.3.10.457
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.457
3n0hTOPDihydrofolate reductase1.5.1.30.457
3zkyWT4Isopenicillin N synthase1.21.3.10.457
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.457
4hfp15UProthrombin3.4.21.50.457
4jvlESTEstrogen sulfotransferase2.8.2.40.457
1s2cFLFAldo-keto reductase family 1 member C3/0.456
1s9dAFBCytohesin-2/0.456
1s9dAFBADP-ribosylation factor 1/0.456
2cbqTH2Neocarzinostatin/0.456
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.456
2f2kTGGAldose reductase1.1.1.210.456
2h447CAcGMP-specific 3',5'-cyclic phosphodiesterase/0.456
2pbzATPUncharacterized protein/0.456
2rd678PPoly [ADP-ribose] polymerase 12.4.2.300.456
2xytTC9Soluble acetylcholine receptor/0.456
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.456
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.456
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.456
3e4vFMNUncharacterized protein/0.456
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.456
3hfbML4Tryptophan 5-hydroxylase 11.14.16.40.456
3mjrAC2Deoxycytidine kinase2.7.1.740.456
3s3gTLTAldose reductase1.1.1.210.456
3szfDCQSulfide-quinone reductase/0.456
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.456
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.456
4a86H35Major pollen allergen Bet v 1-A/0.456
5bn4ANPV-type ATP synthase alpha chain/0.456
1d6w00RProthrombin3.4.21.50.455
1dhfFOLDihydrofolate reductase1.5.1.30.455
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.455
1oxoIK2Aspartate aminotransferase, mitochondrial2.6.1.10.455
1q23FUAChloramphenicol acetyltransferase2.3.1.280.455
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1zgcA2EAcetylcholinesterase3.1.1.70.455
1zuaTOLAldo-keto reductase family 1 member B101.1.10.455
2pdxZSTAldose reductase1.1.1.210.455
2r86ATP5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase/0.455
2xujTZ5Acetylcholinesterase3.1.1.70.455
3gsiTHGDimethylglycine oxidase1.5.3.100.455
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3p5sAVUCD38 molecule/0.455
3u2cSUZAldose reductase1.1.1.210.455
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
4g2wNI0cGMP-specific 3',5'-cyclic phosphodiesterase/0.455
4xoqF42Coenzyme F420:L-glutamate ligase/0.455
5d5aCAUBeta-2 adrenergic receptor/0.455
1e1fPSG4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1, chloroplastic3.2.1.1820.454
1e62FADFerredoxin--NADP reductase1.18.1.20.454
1el4CTZObelin/0.454
1fndFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.454
1gpnHUBAcetylcholinesterase3.1.1.70.454
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.454
1mczRMNBenzoylformate decarboxylase4.1.1.70.454
1o2g696Prothrombin3.4.21.50.454
1pqc444Oxysterols receptor LXR-beta/0.454
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.454
2fa3ACOHydroxymethylglutaryl-CoA synthase/0.454
2jj2ADPATP synthase subunit alpha, mitochondrial/0.454
2jj2ADPATP synthase subunit beta, mitochondrial3.6.3.140.454
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.454
2xncFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.454
3mz9BHNNickel-binding periplasmic protein/0.454
3qwc98PProthrombin3.4.21.50.454
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
3ugrIMNAldo-keto reductase family 1 member C3/0.454
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.454
3znrNU9Histone deacetylase 73.5.1.980.454
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.454
4n9qFMNFMN-dependent NADH-azoreductase 1/0.454
4rsyB3NLeukotriene A-4 hydrolase3.3.2.60.454
4xo7ASDAldo-keto reductase family 1 member C2/0.454
5a4wQCTGlutathione S-transferase F22.5.1.180.454
1afsTES3-alpha-hydroxysteroid dehydrogenase1.1.1.500.453
1ah0SBIAldose reductase1.1.1.210.453
1b2rFADFerredoxin--NADP reductase1.18.1.20.453
1fmlRTLRetinol dehydratase/0.453
1hfrMOTDihydrofolate reductase1.5.1.30.453
1isgAGSADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 23.2.2.60.453
1sb1165Prothrombin3.4.21.50.453
1swnBTNStreptavidin/0.453
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
1udtVIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.453
1yunATPProbable nicotinate-nucleotide adenylyltransferase2.7.7.180.453
1yw8A75Methionine aminopeptidase 2/0.453
1zgv501Prothrombin3.4.21.50.453
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.453
2fzdTOLAldose reductase1.1.1.210.453
2g0gSP0Peroxisome proliferator-activated receptor gamma/0.453
2j3qTFLAcetylcholinesterase3.1.1.70.453
2jh0701Prothrombin3.4.21.50.453
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.453
2xuoTZ4Acetylcholinesterase3.1.1.70.453
2zfq45UProthrombin3.4.21.50.453
3dt4GTPPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.453
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.453
3klbFMNUncharacterized protein/0.453
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.453
3ppkFNISerine/threonine-protein kinase B-raf2.7.11.10.453
3zv7NHGAcetylcholinesterase3.1.1.70.453
4b65NDPL-ornithine N(5)-monooxygenase/0.453
4bfyZVYPantothenate kinase2.7.1.330.453
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.453
4m6l21VDihydrofolate reductase1.5.1.30.453
4pnmNU1Tankyrase-22.4.2.300.453
1mrqSTRAldo-keto reductase family 1 member C1/0.452
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.452
1t7o152Carnitine O-acetyltransferase2.3.1.70.452
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.452
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.452
2ct8MSPMethionine--tRNA ligase6.1.1.100.452
2d06ESTSulfotransferase 1A12.8.2.10.452
2f98NGVAklanonic acid methyl ester cyclase AcmA5.5.1.230.452
2jj2ANPATP synthase subunit beta, mitochondrial3.6.3.140.452
2vbpVB1Isopenicillin N synthase1.21.3.10.452
2zfr46UProthrombin3.4.21.50.452
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3eq02TSProthrombin3.4.21.50.452
3ghrLDTAldose reductase1.1.1.210.452
3h0vM2TS-adenosylmethionine decarboxylase proenzyme4.1.1.500.452
3l6jZ90Alr2278 protein/0.452
3nn6HNK6-hydroxy-L-nicotine oxidase/0.452
3up3XCAaceDAF-12/0.452
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.452
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.452
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.452
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.452
1jf0CZHObelin/0.451
1jqdSAHHistamine N-methyltransferase2.1.1.80.451
1o5gCR9Prothrombin3.4.21.50.451
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.451
1uhhCZPAequorin-2/0.451
1upw444Oxysterols receptor LXR-beta/0.451
1vfsDCSAlanine racemase/0.451
1vhnFMNtRNA-dihydrouridine synthase/0.451
1zisINI6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.451
2jl1NAPTriphenylmethane reductase/0.451
2v58LZJBiotin carboxylase6.3.4.140.451
2xuiTZ5Acetylcholinesterase3.1.1.70.451
2y035FWBeta-1 adrenergic receptor/0.451
2z3uCRRCytochrome P450/0.451
2zf051UProthrombin3.4.21.50.451
3dz2A8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.451
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.451
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.451
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.451
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3ojwFMNNADPH--cytochrome P450 reductase/0.451
3uic09TEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
3znqSS8D-amino-acid oxidase1.4.3.30.451
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.451
4bfvZVVPantothenate kinase2.7.1.330.451
4dvi2IWTankyrase-12.4.2.300.451
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.451
4k4eK4ETankyrase-12.4.2.300.451
4l321VFTankyrase-22.4.2.300.451
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
5cc9DDFDihydrofolate reductase1.5.1.30.451
1ihiIU5Aldo-keto reductase family 1 member C2/0.450
1r5hAO2Methionine aminopeptidase 2/0.450
1sqi8694-hydroxyphenylpyruvate dioxygenase/0.450
1w06W05Isopenicillin N synthase1.21.3.10.450
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2b96ANNPhospholipase A23.1.1.40.450
2c9dPHR6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
2gl0ADNUncharacterized protein/0.450
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
2xlpNAPPutative flavin-containing monooxygenase/0.450
2zevB71Geranylgeranyl pyrophosphate synthase/0.450
2zg050UProthrombin3.4.21.50.450
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.450
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.450
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.450
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.450
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3fhxPLPPyridoxal kinase2.7.1.350.450
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.450
4wctFADFructosyl amine:oxygen oxidoreductase/0.450
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.449
1fvpFMANon-fluorescent flavoprotein/0.449
1rpwDIDHTH-type transcriptional regulator QacR/0.449
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.449
1w87FADFerredoxin--NADP reductase1.18.1.20.449
1ypjUIBProthrombin3.4.21.50.449
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.449
2agtFIDAldose reductase1.1.1.210.449
2aj4ANPGalactokinase2.7.1.60.449
2ea4F79Methionine aminopeptidase 2/0.449
2ejzSAHDiphthine synthase/0.449
2gesCOKPantothenate kinase2.7.1.330.449
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.449
2pnjCHDFerrochelatase, mitochondrial4.99.1.10.449
2vteIK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.449
2znk31UProthrombin3.4.21.50.449
3bmqAX5Pteridine reductase/0.449
3c27DKKProthrombin3.4.21.50.449
3dz7O8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.449
3gf4U5PUDP-galactopyranose mutase5.4.99.90.449
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.449
3hggCHDCmeR/0.449
3iktNADRedox-sensing transcriptional repressor Rex/0.449
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.449
4a16H34Acetylcholinesterase3.1.1.70.449
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.449
4b0532DBeta-secretase 13.4.23.460.449
4fk3325Serine/threonine-protein kinase B-raf2.7.11.10.449
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4m6kFOLDihydrofolate reductase1.5.1.30.449
4n4v2GYTankyrase-12.4.2.300.449
4qtnNNRNicotinamide riboside transporter PnuC/0.449
1bk0ACVIsopenicillin N synthase1.21.3.10.448
1c7oPPGHemolysin/0.448
1fnbFADFerredoxin--NADP reductase, chloroplastic1.18.1.20.448
1gawFADFerredoxin/0.448
1gt5BZQOdorant-binding protein/0.448
1h85FADFerredoxin--NADP reductase1.18.1.20.448
1jwtBLIProthrombin3.4.21.50.448
1qgyFADFerredoxin--NADP reductase1.18.1.20.448
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.448
1rp4FADEndoplasmic oxidoreductin-11.8.40.448
1ypmRA4Prothrombin3.4.21.50.448
2iqdLPAAldose reductase1.1.1.210.448
2pdh47DAldose reductase1.1.1.210.448
2w6cBM4Acetylcholinesterase3.1.1.70.448
2xuhTZ4Acetylcholinesterase3.1.1.70.448
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3eksCY9Actin-5C/0.448
3fznD7KBenzoylformate decarboxylase4.1.1.70.448
3jqgAX6Pteridine reductase, putative/0.448
3nxrD2DDihydrofolate reductase1.5.1.30.448
3p9tTCLRepressor/0.448
3zkuHCVIsopenicillin N synthase1.21.3.10.448
4bjcRPBTankyrase-22.4.2.300.448
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.448
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.448
4lxb7R9Prothrombin3.4.21.50.448
4mv1ADPBiotin carboxylase6.3.4.140.448
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.448
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.448
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.448
1bjkFADFerredoxin--NADP reductase1.18.1.20.447
1d4pBPPProthrombin3.4.21.50.447
1ej3CZHAequorin-2/0.447
1p8dCO1Oxysterols receptor LXR-beta/0.447
1x8lOXRRetinol dehydratase/0.447
1z8962PAldose reductase1.1.1.210.447
2bdyUNBProthrombin3.4.21.50.447
2clfF6FTryptophan synthase alpha chain/0.447
2getCOKPantothenate kinase2.7.1.330.447
2ok8FADFerredoxin--NADP reductase, apicoplast/0.447
2psjCEIRenilla-luciferin 2-monooxygenase1.13.12.50.447
2qw8NAPEugenol synthase 11.1.1.3180.447
2r2mI50Prothrombin3.4.21.50.447
2w6oOA3Biotin carboxylase6.3.4.140.447
2w6qOA5Biotin carboxylase6.3.4.140.447
2xysSY9Soluble acetylcholine receptor/0.447
3dgeADPSensor histidine kinase/0.447
3fpkFADFerredoxin-NADP reductase/0.447
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3nxvD2FDihydrofolate reductase1.5.1.30.447
3qeoLLTDeoxycytidine kinase2.7.1.740.447
3r7mSUZAldo-keto reductase family 1 member C3/0.447
4a3uFMNNADH:flavin oxidoreductase/NADH oxidase/0.447
4br0AU1Ectonucleoside triphosphate diphosphohydrolase 2/0.447
4jvnYUGEstrogen sulfotransferase2.8.2.40.447
4zgsNADPutative D-lactate dehydrogenase/0.447
5dozNDPJamJ/0.447
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.447
2yczI32Beta-1 adrenergic receptor/0.447
5d6lCAUBeta-2 adrenergic receptor/0.447
1c4uIH1Prothrombin3.4.21.50.446
1el3I84Aldose reductase1.1.1.210.446
1icqOPD12-oxophytodienoate reductase 11.3.1.420.446
1m67BOAGlycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal1.1.1.80.446
1nhkCMPNucleoside diphosphate kinase2.7.4.60.446
1paxDHQPoly [ADP-ribose] polymerase 12.4.2.300.446
1pd8CO4Dihydrofolate reductase1.5.1.30.446
1q83TZ5Acetylcholinesterase3.1.1.70.446
1rftPXMPyridoxal kinase2.7.1.350.446
2aovC2MHistamine N-methyltransferase2.1.1.80.446
2ay84TBAromatic-amino-acid aminotransferase2.6.1.570.446
2cf8ESHProthrombin3.4.21.50.446
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.446
2pdaTPPPyruvate synthase/0.446
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.446
3bxxQUEDihydroflavonol 4-reductase1.1.1.2190.446
3g5eQ74Aldose reductase1.1.1.210.446
3l3rOAGDihydrofolate reductase1.5.1.30.446
3n3aFMNProtein NrdI/0.446
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.446
4ax9N5NProthrombin3.4.21.50.446
4boeCLRJapanin/0.446
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.446
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.446
4nv10FXFormyl transferase/0.446
4pabTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.446
4u0sADPAdenosine monophosphate-protein transferase FICD2.7.7.n10.446
5ah5LSSLeucine--tRNA ligase/0.446
6stdMS2Scytalone dehydratase4.2.1.940.446
1gjrFADFerredoxin--NADP reductase1.18.1.20.445
1mtcGPRGlutathione S-transferase Mu 12.5.1.180.445
1oytFSNProthrombin3.4.21.50.445
1t4v14AProthrombin3.4.21.50.445
1xmmM7Gm7GpppX diphosphatase3.6.1.590.445
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1yplRA8Prothrombin3.4.21.50.445
1z5uCMPClass B acid phosphatase/0.445
2gyuHI6Acetylcholinesterase3.1.1.70.445
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.445
2jb4A14Isopenicillin N synthase1.21.3.10.445
2pdfZSTAldose reductase1.1.1.210.445
2xiq5ADMethylmalonyl-CoA mutase, mitochondrial/0.445
3af1GDPPantothenate kinase2.7.1.330.445
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
3dz4C8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.445
3mhpFADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.445
3v35NTIAldose reductase1.1.1.210.445
4bftZVTPantothenate kinase2.7.1.330.445
4e0u0MVCyclic dipeptide N-prenyltransferase/0.445
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.445
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4msg2C6Tankyrase-12.4.2.300.445
4pnrG18Tankyrase-22.4.2.300.445
4yerADPAntibiotic ABC transporter, ATP-binding protein, putative/0.445
1a9cGTPGTP cyclohydrolase 13.5.4.160.444
1db56INPhospholipase A2, membrane associated/0.444
1dlrMXADihydrofolate reductase1.5.1.30.444
1kmsLIHDihydrofolate reductase1.5.1.30.444
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.444
1qjfACSIsopenicillin N synthase1.21.3.10.444
1ry8RUTAldo-keto reductase family 1 member C3/0.444
1tg2H2BPhenylalanine-4-hydroxylase1.14.16.10.444
1u2rSO1Elongation factor 2/0.444
1w6rGNTAcetylcholinesterase3.1.1.70.444
1ygkRRCPyridoxal kinase2.7.1.350.444
1yhjR6CPyridoxal kinase2.7.1.350.444
2pdn47DAldose reductase1.1.1.210.444
2qcxPF1Aminopyrimidine aminohydrolase/0.444
2rcwAAIPoly [ADP-ribose] polymerase 12.4.2.300.444
2yac937Serine/threonine-protein kinase PLK12.7.11.210.444
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3aezGDPPantothenate kinase2.7.1.330.444
3eq6BCOAcyl-coenzyme A synthetase ACSM2A, mitochondrial6.2.1.20.444
3k47D09Dihydrofolate reductase1.5.1.30.444
3pce3HPProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.444
3pce3HPProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.444
4af6FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.444
4bqg50QHeat shock protein HSP 90-alpha/0.444
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.444
4cdmFO1Deoxyribodipyrimidine photolyase/0.444
4iyg1HUStrictosidine synthase4.3.3.20.444
4tnzTTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.444
7stdCRPScytalone dehydratase4.2.1.940.444
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.443
1m51TSXPhosphoenolpyruvate carboxykinase, cytosolic [GTP]4.1.1.320.443
1ndzFR5Adenosine deaminase3.5.4.40.443
1olmVTQSEC14-like protein 2/0.443
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.443
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.443
1ta2176Prothrombin3.4.21.50.443
1tojHCIAspartate aminotransferase2.6.1.10.443
1zknIBMcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.443
2mokFMNFlavodoxin 1/0.443
2ovyPFJcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2pdq47DAldose reductase1.1.1.210.443
2stdCRPScytalone dehydratase4.2.1.940.443
2xukTZ5Acetylcholinesterase3.1.1.70.443
3b03VNRIsopentenyl-diphosphate delta-isomerase/0.443
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.443
3ie3N11Glutathione S-transferase P2.5.1.180.443
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3lxeTORCarbonic anhydrase 14.2.1.10.443
3sfh1DIHistone deacetylase 83.5.1.980.443
3vf60H6Glucokinase2.7.1.20.443
3w0uHPWLactoylglutathione lyase4.4.1.50.443
3w4k3LDD-amino-acid oxidase1.4.3.30.443
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.443
4a33PS8Glycylpeptide N-tetradecanoyltransferase/0.443
4bamMM9Prothrombin3.4.21.50.443
4gd9BTNStreptavidin/0.443
4h1e10JBeta-secretase 13.4.23.460.443
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
4kfjFOLDihydrofolate reductase1.5.1.30.443
4li81XQTankyrase-12.4.2.300.443
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.443
4rxpDTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
4to6TTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.443
1dr4HBIDihydrofolate reductase1.5.1.30.442
1h42FADFerredoxin--NADP reductase1.18.1.20.442
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.442
1oc1ASVIsopenicillin N synthase1.21.3.10.442
1ogjFADFerredoxin--NADP reductase1.18.1.20.442
1pwlBFIAldose reductase1.1.1.210.442
2ewaSB2Mitogen-activated protein kinase 14/0.442
2fzjDH3Dihydrofolate reductase1.5.1.30.442
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.442
2hvoZSTAldose reductase1.1.1.210.442
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.442
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.442
2nn7M29Carbonic anhydrase 14.2.1.10.442
2pb1NFGGlucan 1,3-beta-glucosidase/0.442
2r6jNDPEugenol synthase 11.1.1.3180.442
2rc6FADFerredoxin--NADP reductase/0.442
2uuoLK3UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.442
2v57PRLTetR family transcriptional regulator/0.442
2wn6NDPADP-ribosyltransferase enzymatic component/0.442
2yk2YJXHeat shock protein HSP 90-alpha/0.442
3b9oFMNAlkane monoxygenase/0.442
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3seqNXXGlutamine-dependent NAD(+) synthetase6.3.5.10.442
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
3wavDWVEctonucleotide pyrophosphatase/phosphodiesterase family member 23.1.4.390.442
3zbtFADFerredoxin--NADP reductase1.18.1.20.442
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
4bjbP34Tankyrase-22.4.2.300.442
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.442
4oew5IOcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
4qg0DUTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.442
4to2DGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.442
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.442
4x81MVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.442
5ctoNTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.442
1cqsEQUSteroid Delta-isomerase5.3.3.10.441
1diaL24C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.441
1go2FADFerredoxin--NADP reductase1.18.1.20.441
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.441
1mu6CDAProthrombin3.4.21.50.441
1ogxEQUSteroid Delta-isomerase5.3.3.10.441
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.441
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.441
1s3uTQDDihydrofolate reductase1.5.1.30.441
1ve3SAMUncharacterized protein/0.441
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
2clmF6FTryptophan synthase alpha chain/0.441
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2fapRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.441
2fapRADSerine/threonine-protein kinase mTOR2.7.11.10.441
2jf6S55Strictosidine-O-beta-D-glucosidase3.2.1.1050.441
2pdyFIDAldose reductase1.1.1.210.441
2w3mFOLDihydrofolate reductase1.5.1.30.441
2wu4HBPAcetylcholinesterase3.1.1.70.441
2yg5FADPutrescine oxidase/0.441
2zff53UProthrombin3.4.21.50.441
2zi53L1Deoxycytidine kinase2.7.1.740.441
3b8xG4MPutative pyridoxamine 5-phosphate-dependent dehydrase/0.441
3d2dRENReticuline oxidase1.21.3.30.441
3ekuCY9Actin-5C/0.441
3h0wN8MS-adenosylmethionine decarboxylase proenzyme4.1.1.500.441
3n39FMNProtein NrdI/0.441
3nxyD2HDihydrofolate reductase1.5.1.30.441
3ojxFADNADPH--cytochrome P450 reductase/0.441
4b722FBBeta-secretase 13.4.23.460.441
4g090VDHistidinol dehydrogenase/0.441
4i6f1C7Serine/threonine-protein kinase PLK22.7.11.210.441
4qg1DTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.441
4to1DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.441
4uthFMNXenobiotic reductase/0.441
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.441
1ekoI84Aldose reductase1.1.1.210.440
1m2xMCOMetallo-beta-lactamase type 2/0.440
1nm6L86Prothrombin3.4.21.50.440
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.440
1pke2FDPurine nucleoside phosphorylase DeoD-type/0.440
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
2bjsACVIsopenicillin N synthase1.21.3.10.440
2fahGDPPhosphoenolpyruvate carboxykinase [GTP], mitochondrial4.1.1.320.440
2pdu393Aldose reductase1.1.1.210.440
2r6kGTXGlutathione S-transferase A12.5.1.180.440
2xvhFADPutative flavin-containing monooxygenase/0.440
2ziq26UProthrombin3.4.21.50.440
3ewkFADSensory box histidine kinase/response regulator/0.440
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.440
3q0vLL4HTH-type transcriptional regulator EthR/0.440
3t0kDCQSulfide-quinone reductase/0.440
3w78CBDFMN-dependent NADH-azoreductase/0.440
4hmn16JAldo-keto reductase family 1 member C3/0.440
4i101BSBeta-secretase 13.4.23.460.440
4jpg1OXPyruvate kinase PKM2.7.1.400.440
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
4mm9FVXNa(+):neurotransmitter symporter (Snf family)/0.440
4tnyDGTDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440
4to4DCPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.440