Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 1.000 | |
| 3pcg | 4HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 1.000 | |
| 3pch | CHB | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.793 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.713 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.713 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.572 | |
| 3mfl | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.572 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.562 | |
| 3pcn | DHY | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.562 | |
| 3evb | SAH | Genome polyprotein | 2.1.1.56 | 0.516 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.511 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.508 | |
| 1f9a | ATP | Nicotinamide-nucleotide adenylyltransferase | / | 0.506 | |
| 1cs4 | FOK | Adenylate cyclase type 2 | / | 0.502 | |
| 1cs4 | FOK | Adenylate cyclase type 5 | / | 0.502 | |
| 1cul | FOK | Adenylate cyclase type 2 | / | 0.494 | |
| 1cul | FOK | Adenylate cyclase type 5 | / | 0.494 | |
| 2bf7 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.490 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.490 | |
| 3ebl | GA4 | Gibberellin receptor GID1 | / | 0.490 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.488 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.486 | |
| 3ogw | IMN | Lactoperoxidase | 1.11.1.7 | 0.486 | |
| 3q3c | NAD | NAD-dependent L-serine dehydrogenase | / | 0.486 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.485 | |
| 4kc1 | WS1 | Histo-blood group ABO system transferase | / | 0.484 | |
| 1tou | B1V | Fatty acid-binding protein, adipocyte | / | 0.482 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.482 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.482 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.481 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.480 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.480 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.479 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.479 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.479 | |
| 3koy | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.479 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.478 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.478 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.478 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.477 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.476 | |
| 4itx | IN5 | Cystathionine beta-lyase MetC | 4.4.1.8 | 0.476 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.475 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.474 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 4f3g | KAI | Glutamate receptor 3 | / | 0.474 | |
| 5a3c | NAD | SIR2 family protein | / | 0.474 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.473 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.472 | |
| 2rdn | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.472 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.472 | |
| 3b1d | PLS | BetaC-S lyase | / | 0.472 | |
| 3ipk | PMS | Surface protein adhesin | / | 0.472 | |
| 4rje | FNR | Lactate oxidase | / | 0.472 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.471 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.471 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.471 | |
| 1asc | NPL | Aspartate aminotransferase | 2.6.1.1 | 0.470 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.470 | |
| 2xfs | J01 | Uncharacterized protein | / | 0.470 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.470 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.470 | |
| 4jxr | ACO | Acetyltransferase | / | 0.470 | |
| 1jed | ADP | Sulfate adenylyltransferase | / | 0.469 | |
| 1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.469 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.469 | |
| 3h06 | VBP | Glutamate receptor 2 | / | 0.469 | |
| 4die | C5P | Cytidylate kinase | / | 0.469 | |
| 4nhk | PD2 | Prolyl 3,4-dihydroxylase TPA1 | 1.14.11 | 0.469 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.468 | |
| 1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.468 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.468 | |
| 4gd4 | 0WS | Lysine-specific demethylase 4A | 1.14.11 | 0.468 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.468 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.468 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.468 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.467 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.467 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.467 | |
| 2acw | UPG | Glycosyltransferase | / | 0.467 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.467 | |
| 3u7l | UDB | Peptide deformylase | / | 0.467 | |
| 4ask | K0I | Lysine-specific demethylase 6B | 1.14.11 | 0.467 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.466 | |
| 3ahi | HTL | Probable phosphoketolase | / | 0.466 | |
| 3cgb | COA | Coenzyme A disulfide reductase | / | 0.466 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.466 | |
| 3maa | FKP | Adenylate cyclase type 2 | / | 0.466 | |
| 3maa | FKP | Adenylate cyclase type 5 | / | 0.466 | |
| 2c94 | TSF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.465 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.465 | |
| 3bw4 | FMN | Putative 2-nitropropane dioxygenase | / | 0.465 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.465 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 1xdp | ATP | Polyphosphate kinase | / | 0.464 | |
| 3zhv | TDW | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.464 | |
| 4eso | NAP | Putative oxidoreductase | / | 0.464 | |
| 1ek5 | NAD | UDP-glucose 4-epimerase | / | 0.463 | |
| 1mx0 | ANP | Type 2 DNA topoisomerase 6 subunit B | / | 0.463 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.463 | |
| 2xyd | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.463 | |
| 3suf | SUE | Polyprotein | / | 0.463 | |
| 5ch7 | MGD | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.463 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.462 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.462 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.462 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.462 | |
| 4kxj | P34 | Nucleoprotein | / | 0.462 | |
| 5c6c | CMP | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.462 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.461 | |
| 3lfz | ADP | Uncharacterized protein MJ1225 | / | 0.461 | |
| 3tza | TZG | Glutamate receptor 2 | / | 0.461 | |
| 3zpo | K0I | Histone demethylase UTY | 1.14.11 | 0.461 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.461 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.461 | |
| 4v0s | 2HN | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.461 | |
| 4xg1 | LLP | Diaminopimelate decarboxylase | / | 0.461 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.460 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 3eva | SAH | Genome polyprotein | 2.1.1.56 | 0.460 | |
| 3spt | UD1 | Bifunctional protein GlmU | / | 0.460 | |
| 3wt0 | ATP | Cell division protein FtsA | / | 0.460 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.459 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.459 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.459 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.459 | |
| 2dvo | ITT | dITP/XTP pyrophosphatase | 3.6.1.19 | 0.459 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.459 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.459 | |
| 4n8i | COA | Putative 4-hydroxybutyrate coenzyme A transferase | / | 0.459 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.458 | |
| 2ejz | SAH | Diphthine synthase | / | 0.458 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.458 | |
| 2w6z | L21 | Biotin carboxylase | 6.3.4.14 | 0.458 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.458 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.458 | |
| 4u0z | APC | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.458 | |
| 4ure | 1PS | Cyclohexanol dehydrogenase | / | 0.458 | |
| 4xfj | ANP | Argininosuccinate synthase | / | 0.458 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.457 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.457 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.457 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.457 | |
| 2e0i | FAD | DNA photolyase | / | 0.457 | |
| 2oxn | OAN | Beta-hexosaminidase | / | 0.457 | |
| 2v5a | LZL | Biotin carboxylase | 6.3.4.14 | 0.457 | |
| 3kr6 | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.457 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.457 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 1gpn | HUB | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 1lkd | BP6 | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.456 | |
| 1tl7 | FOK | Adenylate cyclase type 2 | / | 0.456 | |
| 1tl7 | FOK | Adenylate cyclase type 5 | / | 0.456 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.456 | |
| 2wm3 | NFL | NmrA-like family domain-containing protein 1 | / | 0.456 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.456 | |
| 3nw3 | MU2 | Peptidoglycan recognition protein 1 | / | 0.456 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.456 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.456 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.456 | |
| 4hdh | ATP | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.456 | |
| 1b9i | PXG | 3-amino-5-hydroxybenzoate synthase | 4.2.1.144 | 0.455 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.455 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.455 | |
| 1trk | TPP | Transketolase 1 | 2.2.1.1 | 0.455 | |
| 1z5c | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.455 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.455 | |
| 2qo7 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.455 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.455 | |
| 3g0c | RUF | Dipeptidyl peptidase 4 | / | 0.455 | |
| 3o9p | MHI | Periplasmic murein peptide-binding protein | / | 0.455 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.455 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.455 | |
| 4bqy | FNT | Egl nine homolog 1 | / | 0.455 | |
| 2emu | SAH | Diphthine synthase | / | 0.454 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 3fr2 | 8CA | Fatty acid-binding protein, adipocyte | / | 0.454 | |
| 3kb6 | NAD | D-lactate dehydrogenase | / | 0.454 | |
| 4ap1 | NAP | Steroid monooxygenase | / | 0.454 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.454 | |
| 4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.454 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.453 | |
| 1n5q | TNC | ActVA 6 protein | / | 0.453 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.453 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.453 | |
| 2wb2 | FAD | RE11660p | / | 0.453 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.453 | |
| 3eku | CY9 | Actin-5C | / | 0.453 | |
| 3jqp | A2P | Ferredoxin--NADP reductase, apicoplast | / | 0.453 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3opx | U5P | Suppressor of disruption of TFIIS | / | 0.453 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.453 | |
| 4kh0 | ATP | Aspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002} | / | 0.453 | |
| 4m2a | UPG | UDP-glucose pyrophosphorylase | / | 0.453 | |
| 4zwg | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.453 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.453 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.452 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.452 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 2bfa | CB3 | Pteridine reductase 1 | 1.5.1.33 | 0.452 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.452 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.452 | |
| 3ske | 054 | Genome polyprotein | 2.7.7.48 | 0.452 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 4dqu | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.452 | |
| 4idn | GNP | Atlastin-1 | 3.6.5 | 0.452 | |
| 4kc2 | WS2 | Histo-blood group ABO system transferase | / | 0.452 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.452 | |
| 1a9z | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.451 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.451 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.451 | |
| 2dv5 | SAH | Diphthine synthase | / | 0.451 | |
| 2fa3 | ACO | Hydroxymethylglutaryl-CoA synthase | / | 0.451 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.451 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.451 | |
| 2y5s | 78H | Dihydropteroate synthase | / | 0.451 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.451 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.451 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.451 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.451 | |
| 4nxw | ADP | Mitochondrial dynamics protein MID51 | / | 0.451 | |
| 1lbb | KAI | Glutamate receptor 2 | / | 0.450 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.450 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.450 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 2v0u | FMN | NPH1-1 | / | 0.450 | |
| 3ova | APC | CCA-adding enzyme | 2.7.7.72 | 0.450 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 4dja | FAD | (6-4) photolyase | / | 0.450 | |
| 4gk4 | L90 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 4jxx | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.450 | |
| 4qvh | COA | Phosphopantetheinyl transferase PptT (CoA:APO-[ACP]pantetheinephosphotransferase) (CoA:APO-[acyl-carrier protein]pantetheinephosphotransferase) | / | 0.450 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.449 | |
| 1nqu | RDL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.449 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.449 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.449 | |
| 2os1 | BB2 | Peptide deformylase | / | 0.449 | |
| 2wvl | GDD | Mannosyl-3-phosphogylcerate synthase | / | 0.449 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3muo | ZPR | Prolyl endopeptidase | / | 0.449 | |
| 3sso | SAH | Mycinamicin VI 2''-O-methyltransferase | / | 0.449 | |
| 3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.449 | |
| 3zku | HCV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.449 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.449 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.449 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.449 | |
| 4g1f | 0WG | Dipeptidyl peptidase 4 | / | 0.449 | |
| 4gt8 | ADP | Sensor protein VraS | 2.7.13.3 | 0.449 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.448 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.448 | |
| 1tys | DHF | Thymidylate synthase | / | 0.448 | |
| 2eix | FAD | NADH-cytochrome b5 reductase | / | 0.448 | |
| 2ji9 | TPW | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.448 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.448 | |
| 2q46 | NAP | Uncharacterized protein At5g02240 | / | 0.448 | |
| 3clr | FAD | Electron transfer flavoprotein subunit alpha | / | 0.448 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.448 | |
| 3lfm | 3DT | Alpha-ketoglutarate-dependent dioxygenase FTO | / | 0.448 | |
| 4qfx | DGT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.448 | |
| 1a5u | ATP | Pyruvate kinase PKM | 2.7.1.40 | 0.447 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.447 | |
| 1ddu | DDU | Thymidylate synthase | / | 0.447 | |
| 1p0f | NAP | NADP-dependent alcohol dehydrogenase | 1.1.1.2 | 0.447 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.447 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.447 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.447 | |
| 2qbo | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.447 | |
| 2zi5 | 3L1 | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 3b9l | AZZ | Serum albumin | / | 0.447 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.447 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.447 | |
| 3h23 | B54 | Dihydropteroate synthase | / | 0.447 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.447 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.447 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 4i9q | XG4 | DNA-directed DNA polymerase | / | 0.447 | |
| 4ijr | NDP | D-arabinose dehydrogenase [NAD(P)+] heavy chain | 1.1.1.117 | 0.447 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.447 | |
| 5i4n | ATP | Tyrosine-protein kinase JAK2 | / | 0.447 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.447 | |
| 1a8t | 061 | Metallo-beta-lactamase type 2 | / | 0.446 | |
| 1e2j | THM | Thymidine kinase | / | 0.446 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.446 | |
| 1ndc | TYD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.446 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.446 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.446 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.446 | |
| 1v2h | GUN | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2ibz | UQ6 | Cytochrome b | / | 0.446 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.446 | |
| 2x06 | NAD | L-sulfolactate dehydrogenase | / | 0.446 | |
| 2zsi | GA4 | Gibberellin receptor GID1A | 3 | 0.446 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 3gue | UPG | UTP-glucose-1-phosphate uridylyltransferase 2, putative | / | 0.446 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.446 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.446 | |
| 3vnh | FUU | Kelch-like ECH-associated protein 1 | / | 0.446 | |
| 4a39 | GEM | Uncharacterized protein | / | 0.446 | |
| 4aoa | IK2 | Beta-phenylalanine transaminase | 2.6.1 | 0.446 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.446 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.446 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.446 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.446 | |
| 4hs4 | FMN | Chromate reductase | / | 0.446 | |
| 4yaf | 2AM | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 1arg | PPD | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1e2n | RCA | Thymidine kinase | / | 0.445 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.445 | |
| 2bn4 | NAP | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.445 | |
| 2qfv | NAP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.445 | |
| 2qg4 | NAD | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.445 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.445 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.445 | |
| 2w71 | L23 | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 3c36 | KAI | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 3c4v | LIP | D-inositol 3-phosphate glycosyltransferase | 2.4.1.250 | 0.445 | |
| 3ce0 | P34 | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.445 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.445 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.445 | |
| 3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.445 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.445 | |
| 4mv4 | ACP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 4yfy | 0FX | VioF | / | 0.445 | |
| 5cfl | C2E | Stimulator of interferon genes protein | / | 0.445 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.445 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1aqu | EST | Estrogen sulfotransferase, testis isoform | 2.8.2.4 | 0.444 | |
| 1cq6 | PY4 | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.444 | |
| 1dlj | UGA | UDP-glucose 6-dehydrogenase | / | 0.444 | |
| 1ja0 | FMN | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.444 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.444 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2jlb | UDM | Uncharacterized protein | / | 0.444 | |
| 2pv7 | NAD | T-protein | 1.3.1.12 | 0.444 | |
| 3c1y | 2BA | DNA integrity scanning protein DisA | / | 0.444 | |
| 3ncr | ADP | Nitrogen regulatory protein P-II (GlnB-2) | / | 0.444 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 3r6s | CMP | CRP-like cAMP-activated global transcriptional regulator | / | 0.444 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.444 | |
| 4obu | PLP | Pyridoxal-dependent decarboxylase domain protein | / | 0.444 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.444 | |
| 4ros | APR | Malate dehydrogenase | / | 0.444 | |
| 4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 4s1i | PLP | Pyridoxal kinase, putative | / | 0.444 | |
| 4tmc | FMN | Old yellow enzyme | / | 0.444 | |
| 4u0o | MTA | Lipoyl synthase 2 | / | 0.444 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.443 | |
| 1ej2 | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.443 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.443 | |
| 1f28 | UMP | Thymidylate synthase | 2.1.1.45 | 0.443 | |
| 1g7u | PEP | 2-dehydro-3-deoxyphosphooctonate aldolase | 2.5.1.55 | 0.443 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.443 | |
| 1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.443 | |
| 1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.443 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.443 | |
| 1w7i | ADP | Unconventional myosin-Va | / | 0.443 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.443 | |
| 1xnj | ADP | Bifunctional 3'-phosphoadenosine 5'-phosphosulfate synthase 1 | 2.7.1.25 | 0.443 | |
| 2br5 | SAH | Cephalosporin hydroxylase CmcI | / | 0.443 | |
| 2e8h | SAH | Diphthine synthase | / | 0.443 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.443 | |
| 2fna | ADP | Uncharacterized protein | / | 0.443 | |
| 2fyp | RDE | Endoplasmin | / | 0.443 | |
| 2pid | YSA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.443 | |
| 2w02 | ATP | AcsD | / | 0.443 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2x0f | TRH | WsaF | / | 0.443 | |
| 2xh9 | J01 | Uncharacterized protein | / | 0.443 | |
| 2xvv | 9DN | Serum albumin | / | 0.443 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3b2s | B2S | Trichothecene 3-O-acetyltransferase | / | 0.443 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3e39 | FMN | Nitroreductase | / | 0.443 | |
| 3fql | 79Z | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.443 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 4lk3 | NAD | UDP-glucuronic acid decarboxylase 1 | 4.1.1.35 | 0.443 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.443 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 5g53 | NEC | Adenosine receptor A2a | / | 0.443 | |
| 4mqt | 2CU | Muscarinic acetylcholine receptor M2 | / | 0.443 | |
| 1fxo | TMP | Glucose-1-phosphate thymidylyltransferase | / | 0.442 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.442 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.442 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.442 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.442 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.442 | |
| 2bxq | IMN | Serum albumin | / | 0.442 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.442 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.442 | |
| 2x3j | ATP | AcsD | / | 0.442 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.442 | |
| 3frk | TQP | QdtB | / | 0.442 | |
| 3koz | Z97 | D-ornithine 4,5-aminomutase subunit beta | / | 0.442 | |
| 3ru9 | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.442 | |
| 3v0n | 4GW | Histo-blood group ABO system transferase | / | 0.442 | |
| 4cmf | PXG | Uncharacterized protein | / | 0.442 | |
| 4kuh | CAA | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.442 | |
| 4kwe | GDP | Cell division protein FtsZ | / | 0.442 | |
| 4qxq | 1YE | Stimulator of interferon genes protein | / | 0.442 | |
| 4u7w | NDP | MxaA | / | 0.442 | |
| 4x9m | FAD | Uncharacterized protein MG039 homolog | / | 0.442 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.441 | |
| 1csn | ATP | Casein kinase I homolog 1 | 2.7.11.1 | 0.441 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.441 | |
| 1e6z | NGO | Chitinase | / | 0.441 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.441 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.441 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.441 | |
| 1uze | EAL | Angiotensin-converting enzyme | 3.2.1 | 0.441 | |
| 1v93 | FAD | Methylenetetrahydrofolate reductase | / | 0.441 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.441 | |
| 3h4v | DVP | Pteridine reductase 1 | 1.5.1.33 | 0.441 | |
| 3ioe | A7D | Pantothenate synthetase | 6.3.2.1 | 0.441 | |
| 3ivm | ZPR | Prolyl endopeptidase | / | 0.441 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.441 | |
| 4ccq | NAP | Thioredoxin reductase | / | 0.441 | |
| 4ear | IM5 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.441 | |
| 4ifn | 12O | Kelch-like ECH-associated protein 1 | / | 0.441 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.441 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.441 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.441 | |
| 5efw | FMN | NPH1-1 | / | 0.441 | |
| 1a8r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.440 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.440 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1lrj | UD1 | UDP-glucose 4-epimerase | 5.1.3.2 | 0.440 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.440 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.440 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 2dcn | ADP | 2-keto-3-deoxy-gluconate kinase | / | 0.440 | |
| 2ekl | NAD | D-3-phosphoglycerate dehydrogenase | / | 0.440 | |
| 2gpv | OHT | Estrogen-related receptor gamma | / | 0.440 | |
| 2qbr | 910 | Tyrosine-protein phosphatase non-receptor type 1 | 3.1.3.48 | 0.440 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.440 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.440 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 3c0z | SHH | Histone deacetylase 7 | 3.5.1.98 | 0.440 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.440 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.440 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.440 | |
| 3zgz | 84T | Leucine--tRNA ligase | / | 0.440 | |
| 4ho8 | THM | Glucose-1-phosphate thymidylyltransferase | / | 0.440 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.440 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.440 | |
| 5kgp | ACO | Predicted acetyltransferase | / | 0.440 |