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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3k8q22APurine nucleoside phosphorylase2.4.2.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3k8q22APurine nucleoside phosphorylase2.4.2.11.000
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.678
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.639
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.632
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.619
1rszDIHPurine nucleoside phosphorylase2.4.2.10.610
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.609
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.585
1v3q2DIPurine nucleoside phosphorylase2.4.2.10.563
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.560
2on6IMHPurine nucleoside phosphorylase2.4.2.10.558
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.554
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.551
1rctNOSPurine nucleoside phosphorylase2.4.2.10.535
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.534
1a9p9DIPurine nucleoside phosphorylase2.4.2.10.532
1b8oIMHPurine nucleoside phosphorylase2.4.2.10.532
1b8nIMGPurine nucleoside phosphorylase2.4.2.10.527
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.516
1yryMSGPurine nucleoside phosphorylase2.4.2.10.516
1a9sNOSPurine nucleoside phosphorylase2.4.2.10.512
4jicFMNGTN Reductase/0.509
2iyfERYOleandomycin glycosyltransferase2.4.10.505
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.504
3q9bB3NAcetylpolyamine amidohydrolase/0.502
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.498
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.498
4bfzZVZPantothenate kinase2.7.1.330.497
3gwfNAPCyclohexanone monooxygenase/0.494
3p62FMNPentaerythritol tetranitrate reductase/0.494
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.493
4e2bFMNDehydrogenase/0.492
1pf7IMHPurine nucleoside phosphorylase2.4.2.10.491
1qtiGNTAcetylcholinesterase3.1.1.70.491
1v2hGUNPurine nucleoside phosphorylase2.4.2.10.490
3gkaFMNN-ethylmaleimide reductase/0.490
2dsgSAHDiphthine synthase/0.489
2gv8NDPThiol-specific monooxygenase1.14.130.489
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.488
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.487
3zkyWT4Isopenicillin N synthase1.21.3.10.487
4a81DXCMajor pollen allergen Bet v 1-A/0.487
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.486
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.486
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.485
3k8o229Purine nucleoside phosphorylase2.4.2.10.485
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.485
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.484
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.484
1lv89PPPurine nucleoside phosphorylase2.4.2.10.483
2rqfJH3Hemolymph juvenile hormone binding protein/0.483
3atzFMNProstaglandin F2a synthase/0.483
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.482
2w6cBM4Acetylcholinesterase3.1.1.70.482
1h51FMNPentaerythritol tetranitrate reductase/0.481
3h3qH13Collagen type IV alpha-3-binding protein/0.481
3oqfS51Renin3.4.23.150.481
1u65CP0Acetylcholinesterase3.1.1.70.480
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.480
1rfuADPPyridoxal kinase2.7.1.350.479
2cekN8TAcetylcholinesterase3.1.1.70.479
3f03FMNPentaerythritol tetranitrate reductase/0.479
2emrSAHDiphthine synthase/0.478
2ok7FADFerredoxin--NADP reductase, apicoplast/0.478
3f8wADNPurine nucleoside phosphorylase/0.478
3zv7NHGAcetylcholinesterase3.1.1.70.478
4xguADPPutative pachytene checkpoint protein 2/0.478
1xe55FEPlasmepsin-23.4.23.390.477
1eveE20Acetylcholinesterase3.1.1.70.476
1tllFMNNitric oxide synthase, brain1.14.13.390.476
2ejzSAHDiphthine synthase/0.476
2p4sDIHAGAP005945-PA/0.476
4a83DXCMajor pollen allergen Bet v 1-A/0.476
4zj8SUVOrexin receptor type 1/0.476
1h50FMNPentaerythritol tetranitrate reductase/0.475
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.475
1q45FMN12-oxophytodienoate reductase 31.3.1.420.475
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.475
3w8eNAD3-hydroxybutyrate dehydrogenase/0.475
4e2dFMNDehydrogenase/0.475
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.474
1v48HA1Purine nucleoside phosphorylase2.4.2.10.474
3otwCOAPhosphopantetheine adenylyltransferase/0.474
4a862ANMajor pollen allergen Bet v 1-A/0.474
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.474
1hb1OCVIsopenicillin N synthase1.21.3.10.473
2eeqSAHDiphthine synthase/0.473
3atyFMNProstaglandin F2a synthase/0.473
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
3fr5I4AFatty acid-binding protein, adipocyte/0.473
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.473
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.473
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.473
2abbFMNPentaerythritol tetranitrate reductase/0.472
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.472
2he5NDPAldo-keto reductase family 1 member C211.1.10.472
3h3t16HCollagen type IV alpha-3-binding protein/0.472
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.472
4xr9NADCalS8/0.472
5dp2NAPCurF/0.472
1vyrFMNPentaerythritol tetranitrate reductase/0.471
2lfoGCHFatty acid-binding protein, liver/0.471
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.471
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.470
1ia1NDPDihydrofolate reductase1.5.1.30.470
2g1n1IGRenin3.4.23.150.470
2vbdV10Isopenicillin N synthase1.21.3.10.470
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.470
3p82FMNPentaerythritol tetranitrate reductase/0.470
1icpFMN12-oxophytodienoate reductase 11.3.1.420.469
1x1bSAHC-20 methyltransferase/0.469
2i4qUA4Renin3.4.23.150.469
2il2LIXRenin3.4.23.150.469
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.469
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.469
4ey6GNTAcetylcholinesterase3.1.1.70.469
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.469
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.468
3p8iFMNPentaerythritol tetranitrate reductase/0.468
3w2fNADNADH-cytochrome b5 reductase 31.6.2.20.468
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.468
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.468
4bfwZVWPantothenate kinase2.7.1.330.468
2dxvSAHDiphthine synthase/0.467
3widNAPGlucose 1-dehydrogenase/0.467
1h22E10Acetylcholinesterase3.1.1.70.466
1tilATPAnti-sigma F factor/0.466
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.466
2wu4HBPAcetylcholinesterase3.1.1.70.466
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.466
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.466
3gfbNADL-threonine 3-dehydrogenase/0.466
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
3kftNADPentaerythritol tetranitrate reductase/0.466
3p74FMNPentaerythritol tetranitrate reductase/0.466
1bil0IURenin3.4.23.150.465
2gjlFMNNitronate monooxygenase1.13.12.160.465
2ikuLIYRenin3.4.23.150.465
3ohh3HHBeta-secretase 13.4.23.460.465
4bfxZVXPantothenate kinase2.7.1.330.465
4earIM5Purine nucleoside phosphorylase2.4.2.10.465
4frkDWDBeta-secretase 13.4.23.460.465
5irnADPNucleotide binding oligomerization domain containing 2/0.465
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.464
1ni12C5Protein farnesyltransferase subunit beta2.5.1.580.464
1w76GNTAcetylcholinesterase3.1.1.70.464
2dvlFADAcyl-CoA dehydrogenase/0.464
2hs6FMN12-oxophytodienoate reductase 31.3.1.420.464
2iko7IGRenin3.4.23.150.464
2v16C47Renin3.4.23.150.464
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.464
2zbaZBATrichothecene 3-O-acetyltransferase/0.464
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.464
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.464
4s0vSUVOrexin receptor type 2/0.464
1bk0ACVIsopenicillin N synthase1.21.3.10.463
1dirNADDihydropteridine reductase1.5.1.340.463
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.463
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.463
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.463
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.463
2jb4A14Isopenicillin N synthase1.21.3.10.463
3own3OXRenin3.4.23.150.463
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.463
4q73FADBifunctional protein PutA/0.463
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.463
4v12POGMaoC like domain protein/0.463
1ex75GPGuanylate kinase2.7.4.80.462
2iviACWIsopenicillin N synthase1.21.3.10.462
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.462
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.462
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.462
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.462
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.462
1b2lNDCAlcohol dehydrogenase1.1.1.10.461
1cnfFADNitrate reductase [NADH]1.7.1.10.461
1g63FMNEpidermin decarboxylase4.1.10.461
1h60STRPentaerythritol tetranitrate reductase/0.461
1udaUFGUDP-glucose 4-epimerase5.1.3.20.461
1vbiNADMalate/L-lactate dehydrogenase family protein/0.461
2dxwSAHDiphthine synthase/0.461
2e17SAHDiphthine synthase/0.461
2pb4SAHDiphthine synthase/0.461
3bk2U5PRibonuclease J/0.461
4cdmFO1Deoxyribodipyrimidine photolyase/0.461
1e3eNAIAlcohol dehydrogenase 41.1.1.10.460
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.460
2dhfDZFDihydrofolate reductase1.5.1.30.460
2rlcCHDCholoylglycine hydrolase3.5.1.240.460
3k5gBJCBeta-secretase 13.4.23.460.460
3pqbVGPPutative oxidoreductase/0.460
3qeoLLTDeoxycytidine kinase2.7.1.740.460
4c49HCYCorticosteroid-binding globulin/0.460
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.460
4rp8ASCAscorbate-specific PTS system EIIC component/0.460
2gvdFKPAdenylate cyclase type 2/0.459
2gvdFKPAdenylate cyclase type 5/0.459
2pb6SAHDiphthine synthase/0.459
2whqHI6Acetylcholinesterase3.1.1.70.459
3h3r14HCollagen type IV alpha-3-binding protein/0.459
3jusBCDLanosterol 14-alpha demethylase1.14.13.700.459
3vf30GSBeta-secretase 13.4.23.460.459
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.459
4p9dTMPDeoxycytidylate deaminase/0.459
1je1GMPPurine nucleoside phosphorylase/0.458
1rfvADPPyridoxal kinase2.7.1.350.458
2ed3SAHDiphthine synthase/0.458
2pcaSAHDiphthine synthase/0.458
2pncCLUPrimary amine oxidase, liver isozyme/0.458
2q1wNADPutative nucleotide sugar epimerase/ dehydratase/0.458
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.458
3vv8B02Beta-secretase 13.4.23.460.458
3x2fNAIAdenosylhomocysteinase/0.458
4b63NAPL-ornithine N(5)-monooxygenase/0.458
4jqh1MFAlr2278 protein/0.458
1kquBR4Phospholipase A2, membrane associated/0.457
2bjfDXCCholoylglycine hydrolase3.5.1.240.457
2dv4SAHDiphthine synthase/0.457
2el0SAHDiphthine synthase/0.457
2g226IGRenin3.4.23.150.457
2xlrFADPutative flavin-containing monooxygenase/0.457
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.457
3hl0NADMaleylacetate reductase/0.457
3t94MTAS-methyl-5'-thioadenosine phosphorylase/0.457
3v2uATPProtein GAL3/0.457
4a84DXCMajor pollen allergen Bet v 1-A/0.457
4a8v2ANMajor pollen allergen Bet v 1-J/0.457
1cjvFOKAdenylate cyclase type 2/0.456
1cjvFOKAdenylate cyclase type 5/0.456
1h63FMNPentaerythritol tetranitrate reductase/0.456
1icqFMN12-oxophytodienoate reductase 11.3.1.420.456
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.456
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.456
3b6zCO7Enoyl reductase LovC10.456
3zeiAWHO-acetylserine sulfhydrylase/0.456
4ke11R6Beta-secretase 13.4.23.460.456
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.456
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.456
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.455
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.455
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.455
2d29FADAcyl-CoA dehydrogenase/0.455
3a3gDLZLumazine protein/0.455
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3mjrAC2Deoxycytidine kinase2.7.1.740.455
3qt62P0Mevalonate diphosphate decarboxylase/0.455
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.455
3zoiM2WIsopenicillin N synthase1.21.3.10.455
4de2DN3Beta-lactamase/0.455
4e2yJHZMethyltransferase/0.455
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
4m9aFDAAcyl-CoA dehydrogenase/0.455
1bim0QBRenin3.4.23.150.454
1h69ARHNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.454
1oc1ASVIsopenicillin N synthase1.21.3.10.454
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.454
1w6rGNTAcetylcholinesterase3.1.1.70.454
1wklATPNucleoside diphosphate kinase/0.454
2dv3SAHDiphthine synthase/0.454
2ifaFMNUncharacterized protein/0.454
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.454
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.454
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.454
1a9zUPGUDP-glucose 4-epimerase5.1.3.20.453
1fxsNAPGDP-L-fucose synthase/0.453
1g6oADPCag alpha/0.453
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.453
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.453
1wngSAHDiphthine synthase/0.453
2g247IGRenin3.4.23.150.453
2hizLIJBeta-secretase 13.4.23.460.453
2owuSAHDiphthine synthase/0.453
2p83MR0Beta-secretase 13.4.23.460.453
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3h2sNDPPutative NADH-flavin reductase/0.453
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.453
3qe2FMNNADPH--cytochrome P450 reductase/0.453
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.453
4jlm1NNDeoxycytidine kinase2.7.1.740.453
4wdgA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
1e2nRCAThymidine kinase/0.452
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.452
1g6kNADGlucose 1-dehydrogenase1.1.1.470.452
1h74ADPHomoserine kinase2.7.1.390.452
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.452
1mvsDTMDihydrofolate reductase1.5.1.30.452
1pd9CO4Dihydrofolate reductase1.5.1.30.452
1tl7FOKAdenylate cyclase type 2/0.452
1tl7FOKAdenylate cyclase type 5/0.452
1ut6A8NAcetylcholinesterase3.1.1.70.452
2wwjY28Lysine-specific demethylase 4A/0.452
3fazNOSPurine nucleoside phosphorylase/0.452
3ihgVAKAklavinone 12-hydroxylase RdmE/0.452
3zkiWZVBeta-secretase 23.4.23.450.452
4acxS8ZBeta-secretase 13.4.23.460.452
4b722FBBeta-secretase 13.4.23.460.452
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
4rvgTYDD-mycarose 3-C-methyltransferase/0.452
1ad3NADAldehyde dehydrogenase, dimeric NADP-preferring/0.451
1mxfMTXPutative pteridine reductase 2/0.451
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.451
1u71MXADihydrofolate reductase1.5.1.30.451
2c12FADNitroalkane oxidase1.7.3.10.451
2huxSAHDiphthine synthase/0.451
2oapANPType II secretion system protein (GspE-2)/0.451
2p6lSAHDiphthine synthase/0.451
2pckSAHDiphthine synthase/0.451
2watCOAFatty acid synthase subunit alpha2.3.1.860.451
2xysSY9Soluble acetylcholine receptor/0.451
3fnlSHALactoperoxidase/0.451
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3qvrFADGlucose oxidase1.1.3.40.451
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.451
4m83ERYOleandomycin glycosyltransferase2.4.10.451
4q71FADBifunctional protein PutA/0.451
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.451
1adfTADAlcohol dehydrogenase E chain1.1.1.10.450
1drfFOLDihydrofolate reductase1.5.1.30.450
2c20NADUDP-glucose 4-epimerase/0.450
2dsiSAHDiphthine synthase/0.450
2g1y5IGRenin3.4.23.150.450
2gesCOKPantothenate kinase2.7.1.330.450
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.450
2qimZEAClass 10 plant pathogenesis-related protein/0.450
3adaNADSubunit alpha of sarocosine oxidase/0.450
3cotSTR3-oxo-5-beta-steroid 4-dehydrogenase/0.450
3hdyGDUUDP-galactopyranose mutase/0.450
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.450
3qbjNXZDipeptidyl peptidase 4/0.450
3s1dZIRCytokinin dehydrogenase 11.5.99.120.450
4esoNAPPutative oxidoreductase/0.450
4m0f1YKAcetylcholinesterase3.1.1.70.450
4wriOKAOkadaic acid binding protein 2-alpha/0.450
4ycpFMNtRNA-dihydrouridine(16) synthase/0.450
1hb3SCVIsopenicillin N synthase1.21.3.10.449
1me6IVSPlasmepsin-23.4.23.390.449
1rneC60Renin3.4.23.150.449
2a5kAZPReplicase polyprotein 1ab3.4.220.449
2cy0NAPShikimate dehydrogenase (NADP(+))/0.449
2ea4F79Methionine aminopeptidase 2/0.449
2eldSAHDiphthine synthase/0.449
2g8yNADHydroxycarboxylate dehydrogenase B/0.449
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.449
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.449
2wf1ZY1Beta-secretase 13.4.23.460.449
2xq0BESLeukotriene A-4 hydrolase homolog3.3.2.60.449
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.449
3aosJH2Hemolymph juvenile hormone binding protein/0.449
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.449
3mknDNBPyrimidine-specific ribonucleoside hydrolase RihB/0.449
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.449
3phiNDPShikimate dehydrogenase (NADP(+))/0.449
3uylTYDProbable NDP-rhamnosyltransferase/0.449
4b4vL34Bifunctional protein FolD/0.449
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.449
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.449
4iae1DXAlr2278 protein/0.449
4loh1SYStimulator of interferon genes protein/0.449
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.449
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.449
1icsFMN12-oxophytodienoate reductase 11.3.1.420.448
1u4oNDDL-lactate dehydrogenase1.1.1.270.448
2e8hSAHDiphthine synthase/0.448
2ek7SAHDiphthine synthase/0.448
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.448
2h3wHC5Carnitine O-acetyltransferase2.3.1.70.448
2ha6SCKAcetylcholinesterase3.1.1.70.448
2hs8FMN12-oxophytodienoate reductase 31.3.1.420.448
2vkeTACTetracycline repressor protein class D/0.448
3c3xNAPEugenol synthase 11.1.1.3180.448
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.448
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.448
3fr28CAFatty acid-binding protein, adipocyte/0.448
3k5c0BIBeta-secretase 13.4.23.460.448
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.448
4a802ANMajor pollen allergen Bet v 1-A/0.448
4b68NAPL-ornithine N(5)-monooxygenase/0.448
4gl4NAIAlcohol dehydrogenase class-3/0.448
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.448
1bwsNDPGDP-L-fucose synthase/0.447
1gpnHUBAcetylcholinesterase3.1.1.70.447
1j78VDYVitamin D-binding protein/0.447
1jwtBLIProthrombin3.4.21.50.447
1mmkH4BPhenylalanine-4-hydroxylase1.14.16.10.447
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1tcoFK5Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.447
1tcoFK5Serine/threonine-protein phosphatase 2B catalytic subunit alpha isoform3.1.3.160.447
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.447
2e8qSAHDiphthine synthase/0.447
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.447
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.447
2i7nACOPantothenate kinase 12.7.1.330.447
2xuqTZ4Acetylcholinesterase3.1.1.70.447
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.447
3lqsPSZD-alanine aminotransferase2.6.1.210.447
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.447
3p67FMNPentaerythritol tetranitrate reductase/0.447
3sf6FDAGlutaryl-CoA dehydrogenase/0.447
3vsxR32Renin3.4.23.150.447
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.447
4fm80UQBeta-secretase 13.4.23.460.447
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.447
4kbyC2EStimulator of interferon genes protein/0.447
4y1bNAPAntE/0.447
1cf3FADGlucose oxidase1.1.3.40.446
1dr3TAPDihydrofolate reductase1.5.1.30.446
1j49NADD-lactate dehydrogenase1.1.1.280.446
1rzuADPGlycogen synthase 12.4.1.210.446
1s3uTQDDihydrofolate reductase1.5.1.30.446
1tehNADAlcohol dehydrogenase class-31.1.1.10.446
1w19T5P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
1xagNAD3-dehydroquinate synthase/0.446
2dshSAHDiphthine synthase/0.446
2e8rSAHDiphthine synthase/0.446
2g0bNLTLong-chain N-acyl amino acid synthase/0.446
2i7pACOPantothenate kinase 32.7.1.330.446
2vbpVB1Isopenicillin N synthase1.21.3.10.446
2x93X93Angiotensin-converting enzyme3.4.15.10.446
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.446
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3ed1GA3Gibberellin receptor GID1/0.446
3h06VBPGlutamate receptor 2/0.446
3iexGMPPurine nucleoside phosphorylase/0.446
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3lqfNADGalactitol dehydrogenase/0.446
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.446
3uzxAOX3-oxo-5-beta-steroid 4-dehydrogenase/0.446
3vqsJT1Genome polyprotein/0.446
4bftZVTPantothenate kinase2.7.1.330.446
4drhRAPSerine/threonine-protein kinase mTOR2.7.11.10.446
4drhRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.446
4g3jVNTLanosterol 14-alpha-demethylase/0.446
4g95OAGDihydrofolate reductase1.5.1.30.446
4jjiNADAlcohol dehydrogenase class-3/0.446
4loi1YCStimulator of interferon genes protein/0.446
4lutDCSAlanine racemase/0.446
5fltVJJCarbonic anhydrase 24.2.1.10.446
1dr2TAPDihydrofolate reductase1.5.1.30.445
1f4fTP3Thymidylate synthase/0.445
1fm4DXCMajor pollen allergen Bet v 1-L/0.445
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.445
1o9bNAIQuinate/shikimate dehydrogenase/0.445
1pqc444Oxysterols receptor LXR-beta/0.445
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.445
1sdwIYTPeptidyl-glycine alpha-amidating monooxygenase1.14.17.30.445
1t7o152Carnitine O-acetyltransferase2.3.1.70.445
1w6hTITPlasmepsin-23.4.23.390.445
1x8lOXRRetinol dehydratase/0.445
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.445
2fn7NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.445
2ylxNAPPhenylacetone monooxygenase1.14.13.920.445
3nmpPYVAbscisic acid receptor PYL2/0.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3vg10GTBeta-secretase 13.4.23.460.445
4bfyZVYPantothenate kinase2.7.1.330.445
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.445
4df2FMNNADPH dehydrogenase/0.445
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.445
4q72FADBifunctional protein PutA/0.445
4zlaBESCytosol aminopeptidase3.4.11.10.445
5bnw12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.445
1esmCOAPantothenate kinase2.7.1.330.444
1g45FSBCarbonic anhydrase 24.2.1.10.444
1o97FADElectron transfer flavoprotein subunit alpha/0.444
2g25TDKPyruvate dehydrogenase E1 component1.2.4.10.444
2gevCOKPantothenate kinase2.7.1.330.444
2v57PRLTetR family transcriptional regulator/0.444
2v8pCDP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.444
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.444
3koyZ97D-ornithine 4,5-aminomutase subunit beta/0.444
3oqkS52Renin3.4.23.150.444
3to3ATPPetrobactin biosynthesis protein AsbB/0.444
3zhuTD8Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.444
4f5yC2EStimulator of interferon genes protein/0.444
4zzi1NSNAD-dependent protein deacetylase sirtuin-13.5.10.444
1fmjRTLRetinol dehydratase/0.443
1xdsDRAAclacinomycin 10-hydroxylase RdmB4.1.10.443
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
2ejjSAHDiphthine synthase/0.443
2g20L1ARenin3.4.23.150.443
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3c36KAIGlutamate receptor ionotropic, kainate 1/0.443
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.443
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.443
3gnvXNZGenome polyprotein2.7.7.480.443
3gqvNAPEnoyl reductase LovC10.443
3qgf46FGenome polyprotein2.7.7.480.443
3tjzGNPADP-ribosylation factor 1/0.443
4a87NARMajor pollen allergen Bet v 1-A/0.443
4acuQN7Beta-secretase 13.4.23.460.443
4bf9FMNtRNA-dihydrouridine(16) synthase/0.443
4dbzNDPPutative ketoacyl reductase1.3.10.443
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.443
4fxy0W2Neurolysin, mitochondrial3.4.24.160.443
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.443
4mv1ADPBiotin carboxylase6.3.4.140.443
4r81FMNPredicted NADH dehydrogenase/0.443
4uugPXGBranched-chain amino acid aminotransferase, putative/0.443
4wecNADShort chain dehydrogenase/0.443
5czySAMEukaryotic huntingtin interacting protein B/0.443
1cdoNADAlcohol dehydrogenase 11.1.1.10.442
1dhfFOLDihydrofolate reductase1.5.1.30.442
1ds7FMNOxygen-insensitive NAD(P)H nitroreductase/0.442
1g1aNADdTDP-glucose 4,6-dehydratase/0.442
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.442
1tqf32PBeta-secretase 13.4.23.460.442
1u1gBBBUridine phosphorylase2.4.2.30.442
1x1cSAHC-20 methyltransferase/0.442
1xz85GPBifunctional protein PyrR2.4.2.90.442
1zgbA1EAcetylcholinesterase3.1.1.70.442
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.442
2a8yMTAS-methyl-5'-thioadenosine phosphorylase/0.442
2emuSAHDiphthine synthase/0.442
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
2g1o2IGRenin3.4.23.150.442
2geuCOKPantothenate kinase2.7.1.330.442
2p9dSAHDiphthine synthase/0.442
2zvcSAHPrecorrin-3 C17-methyltransferase/0.442
3bw4FMNPutative 2-nitropropane dioxygenase/0.442
3ddw055Glycogen phosphorylase, liver form2.4.1.10.442
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.442
3gwfFADCyclohexanone monooxygenase/0.442
3imgBZ2Pantothenate synthetase6.3.2.10.442
3mauEXTPutative sphingosine-1-phosphate lyase/0.442
3t7p7SPEndothiapepsin3.4.23.220.442
4dptAGSMevalonate diphosphate decarboxylase/0.442
4ead0NPThymidine phosphorylase2.4.2.40.442
5fd8A5APutative carboxypeptidase yocD/0.442
1cqp803Integrin alpha-L/0.441
1gpeFADGlucose oxidase1.1.3.40.441
1mvtDTMDihydrofolate reductase1.5.1.30.441
1towCRZFatty acid-binding protein, adipocyte/0.441
1u2yGOXPancreatic alpha-amylase/0.441
1v453DGPurine nucleoside phosphorylase2.4.2.10.441
1xe65FPPlasmepsin-23.4.23.390.441
1xvaSAMGlycine N-methyltransferase2.1.1.200.441
1y6oMJIPhospholipase A2, major isoenzyme3.1.1.40.441
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.441
2dxdANPNucleoside diphosphate kinase2.7.4.60.441
2e1zB4PPropionate kinase/0.441
2z7hGG3Geranylgeranyl pyrophosphate synthase/0.441
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.441
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.441
3fznD7KBenzoylformate decarboxylase4.1.1.70.441
3in6FMNUncharacterized protein/0.441
3ivcFG4Pantothenate synthetase6.3.2.10.441
3ju8NADN-succinylglutamate 5-semialdehyde dehydrogenase1.2.1.710.441
3l3lL3LPoly [ADP-ribose] polymerase 12.4.2.300.441
4bfuZVUPantothenate kinase2.7.1.330.441
4bfvZVVPantothenate kinase2.7.1.330.441
4ck2NVUIntegrase/0.441
4u7wNDPMxaA/0.441
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4xrbNDPPossible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc/0.441
5f8eSAHPossible transcriptional regulatory protein/0.441
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1e66HUXAcetylcholinesterase3.1.1.70.440
1xs7MMIBeta-secretase 13.4.23.460.440
2ejkSAHDiphthine synthase/0.440
2ekaSAHDiphthine synthase/0.440
2jkvNAP6-phosphogluconate dehydrogenase, decarboxylating1.1.1.440.440
2xupTZ5Acetylcholinesterase3.1.1.70.440
2xw19NVSerum albumin/0.440
3apwDP0Alpha-1-acid glycoprotein 2/0.440
3d84NDPDihydrofolate reductase1.5.1.30.440
3fstFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.440
3o4rNAPDehydrogenase/reductase SDR family member 41.1.1.1840.440
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.440
4cukNAID-lactate dehydrogenase/0.440
4du6GTPGTP cyclohydrolase 1/0.440
4fweFADLysine-specific histone demethylase 1B10.440
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.440
4l5aTBNS-methyl-5'-thioadenosine phosphorylase/0.440
4oztP1AEcdysone receptor, putative/0.440
4rww2BALmo2692 protein/0.440
4x5gFOLDihydrofolate reductase1.5.1.30.440