sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.896 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.883 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.879 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.863 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.861 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.860 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.857 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.857 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.853 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.847 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.846 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.835 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.831 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.826 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.814 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.813 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.805 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.796 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.796 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.794 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.790 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.789 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.788 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.784 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.775 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.768 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.766 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.760 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.759 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.754 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.753 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.746 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.743 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.741 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.740 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.733 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.732 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.726 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.724 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.723 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.720 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.717 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.715 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.714 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.712 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.711 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.710 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.706 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.681 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.680 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.663 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.654 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.652 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.633 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.613 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.609 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.593 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.589 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.581 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.578 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.578 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.570 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.569 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.568 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.567 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.560 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.544 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.542 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.541 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.541 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.535 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.535 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.528 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.520 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.514 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.511 | |
| 1sa4 | JAN | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.505 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.505 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.498 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.496 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.495 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.495 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.494 | |
| 1kyx | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.491 | |
| 4aws | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.491 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.489 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.489 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.489 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.488 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.488 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.488 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.486 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.486 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.486 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.485 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.484 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.484 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.483 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.483 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.482 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.482 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.482 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.481 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.480 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.480 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.480 | |
| 1jcq | 739 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.479 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 1s63 | 778 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.479 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.479 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.479 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.478 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.477 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.477 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.476 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.476 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.476 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
| 1qpf | 858 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.475 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.475 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.475 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.474 | |
| 3qbj | NXZ | Dipeptidyl peptidase 4 | / | 0.474 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.474 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.474 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.474 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.473 | |
| 1q45 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.473 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.473 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.473 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.473 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.472 | |
| 3u57 | DH8 | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.472 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.472 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.472 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.471 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.471 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.471 | |
| 3vil | SA0 | Beta-glucosidase | / | 0.471 | |
| 1mzc | BNE | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.470 | |
| 2q3o | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.470 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.470 | |
| 4u3j | GTP | Tubulin beta chain | / | 0.470 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.469 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.469 | |
| 3ksq | Z96 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.469 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.469 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.469 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.468 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.468 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.468 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.468 | |
| 4e2d | FMN | Dehydrogenase | / | 0.468 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.467 | |
| 4de0 | 0JB | Beta-lactamase | / | 0.467 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.466 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.466 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.466 | |
| 1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.466 | |
| 2dg4 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.466 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.466 | |
| 3e32 | ED2 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.466 | |
| 3ha3 | SAH | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.466 | |
| 4dz2 | FK5 | Peptidyl-prolyl cis-trans isomerase | / | 0.466 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.466 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.465 | |
| 2an9 | GDP | Guanylate kinase | 2.7.4.8 | 0.465 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.465 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4gtr | 7TR | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.465 | |
| 4rel | KMP | Glycosyltransferase | / | 0.465 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.464 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.464 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.464 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.464 | |
| 3lzw | NAP | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.464 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.464 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.463 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.463 | |
| 2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.463 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.463 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.463 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.463 | |
| 4jiq | 1L5 | GTN Reductase | / | 0.463 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.463 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.462 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.462 | |
| 2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.462 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.462 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.462 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.462 | |
| 4de2 | DN3 | Beta-lactamase | / | 0.462 | |
| 4jic | FMN | GTN Reductase | / | 0.462 | |
| 4rnu | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.462 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.462 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.461 | |
| 1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.461 | |
| 1wzi | NDP | Malate dehydrogenase | / | 0.461 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.461 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.461 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.461 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.461 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.461 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.460 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.460 | |
| 4drk | I63 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.460 | |
| 5bnw | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.460 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.459 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.459 | |
| 2b3v | ACO | Diamine acetyltransferase 1 | / | 0.459 | |
| 2fbw | CBE | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.459 | |
| 2fbw | CBE | Succinate dehydrogenase cytochrome b, large subunit | / | 0.459 | |
| 2gou | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.459 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.459 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 4e31 | JHZ | Methyltransferase | / | 0.459 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.459 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.458 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.458 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.458 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.458 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.458 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.458 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.458 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.458 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.458 | |
| 1fkb | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.457 | |
| 1h62 | ANB | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 1mmk | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.457 | |
| 1yw7 | A41 | Methionine aminopeptidase 2 | / | 0.457 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 3e33 | ED7 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.457 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 3toz | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.457 | |
| 3w3n | RX8 | Toll-like receptor 8 | / | 0.457 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.457 | |
| 1j4h | SUB | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.456 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.456 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.456 | |
| 2vf3 | GVS | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.456 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3nbr | ASD | Steroid Delta-isomerase | 5.3.3.1 | 0.456 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.456 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.456 | |
| 1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.455 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.455 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.455 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.455 | |
| 2ffq | GSP | Ras-related protein Rab-6B | / | 0.455 | |
| 2r5n | TPP | Transketolase 1 | / | 0.455 | |
| 3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.455 | |
| 3zid | GDP | Tubulin-like protein CetZ | / | 0.455 | |
| 4awt | FMN | NADH:flavin oxidoreductase Sye1 | / | 0.455 | |
| 4bf9 | FMN | tRNA-dihydrouridine(16) synthase | / | 0.455 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.455 | |
| 4e2b | FMN | Dehydrogenase | / | 0.455 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.455 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.455 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.455 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.454 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.454 | |
| 2g25 | TDK | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.454 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.454 | |
| 3dzi | RGT | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.454 | |
| 3eks | CY9 | Actin-5C | / | 0.454 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.454 | |
| 3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.454 | |
| 3vuc | HHE | Renin | 3.4.23.15 | 0.454 | |
| 4lay | I63 | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.454 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.454 | |
| 5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 1aka | PLP | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.453 | |
| 1fkf | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.453 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.453 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.453 | |
| 2a84 | ATP | Pantothenate synthetase | 6.3.2.1 | 0.453 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.453 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.453 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.453 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.453 | |
| 3aty | FMN | Prostaglandin F2a synthase | / | 0.453 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.453 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.453 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.453 | |
| 3s87 | ADP | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.453 | |
| 4b63 | NAP | L-ornithine N(5)-monooxygenase | / | 0.453 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.453 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.453 | |
| 4iah | 1DX | Alr2278 protein | / | 0.453 | |
| 1kp2 | ATP | Argininosuccinate synthase | 6.3.4.5 | 0.452 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.452 | |
| 2vq7 | NAP | Putative flavin-containing monooxygenase | / | 0.452 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 4drm | 0MC | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.452 | |
| 4fmx | CNL | 1,8-cineole 2-endo-monooxygenase | 1.14.13.156 | 0.452 | |
| 1e2n | RCA | Thymidine kinase | / | 0.451 | |
| 1gve | NAP | Aflatoxin B1 aldehyde reductase member 3 | 1 | 0.451 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.451 | |
| 1u1f | 183 | Uridine phosphorylase | 2.4.2.3 | 0.451 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.451 | |
| 2dg3 | RAP | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.451 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.451 | |
| 2v2z | ADP | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.451 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.451 | |
| 3b9x | NOS | Pyrimidine-specific ribonucleoside hydrolase RihB | 3.2.2.8 | 0.451 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.451 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.451 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.451 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 4js1 | CTN | Beta-galactoside alpha-2,6-sialyltransferase 1 | 2.4.99.1 | 0.451 | |
| 4ykl | GMP | Aprataxin-like protein | 3 | 0.451 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.450 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.450 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 2b4d | COA | Diamine acetyltransferase 1 | / | 0.450 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.450 | |
| 3a0t | ADP | Sensor histidine kinase | / | 0.450 | |
| 3akn | 11D | Fatty acid-binding protein, intestinal | / | 0.450 | |
| 3cgt | BCD | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.450 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.450 | |
| 3ou2 | SAH | SAM-dependent methyltransferase | / | 0.450 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.450 | |
| 3v2u | ATP | Protein GAL3 | / | 0.450 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.450 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.450 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.450 | |
| 4l5a | TBN | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.449 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.449 | |
| 2wu4 | HBP | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.449 | |
| 3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.449 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.449 | |
| 4bqz | GNP | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.449 | |
| 4n1g | CEI | Obelin | / | 0.449 | |
| 5b1y | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.449 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.448 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
| 1vjt | NAD | Alpha-glucosidase, putative | / | 0.448 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.448 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.448 | |
| 4f5y | C2E | Stimulator of interferon genes protein | / | 0.448 | |
| 4gdc | NDP | UDP-galactopyranose mutase | / | 0.448 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.448 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.448 | |
| 4z0p | NDP | NAD-dependent dehydrogenase | / | 0.448 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.448 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.447 | |
| 1nqw | 5YL | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.447 | |
| 1q5m | NDP | Prostaglandin-E(2) 9-reductase | 1.1.1.189 | 0.447 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.447 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.447 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.447 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.447 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.447 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.447 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4f5d | C2E | Stimulator of interferon genes protein | / | 0.447 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.447 | |
| 5a0y | COM | Methyl-coenzyme M reductase I subunit beta | 2.8.4.1 | 0.447 | |
| 1bil | 0IU | Renin | 3.4.23.15 | 0.446 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.446 | |
| 1m9a | GTX | Glutathione S-transferase class-mu 26 kDa isozyme | 2.5.1.18 | 0.446 | |
| 1og4 | NAI | T-cell ecto-ADP-ribosyltransferase 2 | / | 0.446 | |
| 1ur5 | NAD | Malate dehydrogenase | / | 0.446 | |
| 1xvt | COA | L-carnitine CoA-transferase | / | 0.446 | |
| 2gqg | 1N1 | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.446 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.446 | |
| 2ylt | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.446 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.446 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.446 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.446 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.446 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.446 | |
| 4ira | FAD | 4-hydroxyphenylacetate 3-monooxygenase | / | 0.446 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 1ejb | INJ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.445 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.445 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.445 | |
| 2w2v | GTP | Ras-related C3 botulinum toxin substrate 2 | / | 0.445 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.445 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3m2v | COM | Methyl-coenzyme M reductase I subunit alpha | 2.8.4.1 | 0.445 | |
| 3uxv | GUN | NADPH-dependent 7-cyano-7-deazaguanine reductase | / | 0.445 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.445 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.444 | |
| 1nzx | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.444 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.444 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.444 | |
| 1xag | NAD | 3-dehydroquinate synthase | / | 0.444 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.444 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.444 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.444 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.444 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.444 | |
| 3tjl | FMN | NADPH dehydrogenase | / | 0.444 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.444 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.444 | |
| 4fhd | 0TT | Spore photoproduct lyase | / | 0.444 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.444 | |
| 4qfy | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.444 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.444 | |
| 1fcb | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.443 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.443 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.443 | |
| 1uag | UMA | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.443 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.443 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.443 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.443 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.443 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.443 | |
| 2gyw | OBI | Acetylcholinesterase | 3.1.1.7 | 0.443 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.443 | |
| 2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.443 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.443 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.443 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3eku | CY9 | Actin-5C | / | 0.443 | |
| 3g0g | RUM | Dipeptidyl peptidase 4 | / | 0.443 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.443 | |
| 3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.443 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.443 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.443 | |
| 4iae | 1DX | Alr2278 protein | / | 0.443 | |
| 4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.443 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 1v3q | 2DI | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.442 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 3koq | FMN | Putative nitroreductase | / | 0.442 | |
| 3opm | LUI | Dipeptidyl peptidase 4 | / | 0.442 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.442 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.442 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.442 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.442 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.442 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.442 | |
| 1bxs | NAD | Retinal dehydrogenase 1 | 1.2.1.36 | 0.441 | |
| 1mxi | SAH | tRNA (cytidine(34)-2'-O)-methyltransferase | / | 0.441 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.441 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.441 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.441 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.441 | |
| 2g21 | L1B | Renin | 3.4.23.15 | 0.441 | |
| 2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.441 | |
| 2j08 | FAD | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.441 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.441 | |
| 3dr4 | G4M | GDP-perosamine synthase | / | 0.441 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.441 | |
| 3e23 | SAM | Uncharacterized protein | / | 0.441 | |
| 3hlw | CE3 | Beta-lactamase | / | 0.441 | |
| 3o5r | FK5 | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.441 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.441 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 3qvi | K95 | HAP protein | / | 0.441 | |
| 3std | MQ0 | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 3vjk | M51 | Dipeptidyl peptidase 4 | / | 0.441 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.441 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.441 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.441 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.440 | |
| 1jzq | ILA | Isoleucine--tRNA ligase | 6.1.1.5 | 0.440 | |
| 1u2y | GOX | Pancreatic alpha-amylase | / | 0.440 | |
| 1vji | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.440 | |
| 2a5h | SAM | L-lysine 2,3-aminomutase | 5.4.3.2 | 0.440 | |
| 2b3d | FAD | Modulator of drug activity B | / | 0.440 | |
| 2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.440 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.440 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.440 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 3c1o | NAP | Eugenol synthase | / | 0.440 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.440 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.440 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.440 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.440 | |
| 3zec | ANP | Adenosine monophosphate-protein transferase SoFic | 2.7.7.n1 | 0.440 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.440 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.440 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.440 | |
| 4tnz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 |