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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
1lcwSHMStreptavidin

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
1lcwSHMStreptavidin/1.000
2izhBTNStreptavidin/0.707
2rtoIMIStreptavidin/0.694
3ry2BTNStreptavidin/0.691
2rtdBTNStreptavidin/0.689
2rtfBTNStreptavidin/0.687
2rtgBTNStreptavidin/0.684
1sreHABStreptavidin/0.669
2rteBTNStreptavidin/0.669
4dneDTBStreptavidin/0.668
4gdaBTNStreptavidin/0.666
4bx7B4FStreptavidin/0.665
2rtqIMIStreptavidin/0.662
1stpBTNStreptavidin/0.656
2izlIMIStreptavidin/0.656
2y3fBTNStreptavidin/0.656
3wyqBTNStreptavidin/0.655
2izfBTNStreptavidin/0.647
1mk5BTNStreptavidin/0.646
2rtnIMIStreptavidin/0.645
2rtrIMIStreptavidin/0.645
2izgBTNStreptavidin/0.644
2izkGLLStreptavidin/0.638
1sriDMBStreptavidin/0.634
1srgMHBStreptavidin/0.629
2rtiGLLStreptavidin/0.627
1srfMTBStreptavidin/0.620
1i9hBNIStreptavidin/0.616
2fhnBNIAvidin-related protein 4/5/0.614
1swtBTNStreptavidin/0.613
1srhMOBStreptavidin/0.610
2rtkGLLStreptavidin/0.608
1df8BTNStreptavidin/0.605
1rxhBNIStreptavidin/0.603
2izjBTNStreptavidin/0.600
3wznBTNStreptavidin/0.598
2aviBTNAvidin/0.594
1lczBH7Streptavidin/0.593
2rtpIMIStreptavidin/0.592
1y52BTNAvidin-related protein 4/5/0.591
1luqBTNStreptavidin/0.583
3t2wBTNAvidin/streptavidin/0.582
1srjNABStreptavidin/0.579
2c4iBTNAvidin/0.572
1avdBTNAvidin/0.567
2iziBTNStreptavidin/0.567
1swpBTQStreptavidin/0.563
1ndjBTNStreptavidin/0.555
3rdqDTBStreptavidin/0.555
1n9mBTNStreptavidin/0.551
3ew2BTNHypothetical conserved protein/0.549
4bcsBTNAvidin-related protein 4/5/0.549
1nc9IMIStreptavidin/0.548
2uz2BTNAvd protein/0.545
2uywBTNAvd protein/0.544
4z28BTNHoefavidin/0.543
2zscBTNTamavidin2/0.538
2rtmIMIStreptavidin/0.536
2fhlBNIAvidin-related protein 4/5/0.535
1sweBTNStreptavidin/0.531
2jgsBTNAvidin/0.531
3wypBSOStreptavidin/0.530
1swpBTNStreptavidin/0.523
4psbGA3Cytokinin-specific binding protein/0.520
1lkeDOGBilin-binding protein/0.513
4gd9BTNStreptavidin/0.509
1mepBTNStreptavidin/0.508
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.508
2o1xTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.507
4dz7D02Carbonic anhydrase 24.2.1.10.501
4bj8BTNAvidin/0.500
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.499
3c3xNAPEugenol synthase 11.1.1.3180.495
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.493
4ggzBTNBll1558 protein/0.491
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.489
3vgwNVZAvidin/0.489
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.488
4ts7ADPPurine phosphoribosyltransferase (GpT-1)/0.488
1h51FMNPentaerythritol tetranitrate reductase/0.487
4zwpM44Xaa-Pro dipeptidase3.4.13.90.487
1el4CTZObelin/0.486
2r6jNDPEugenol synthase 11.1.1.3180.486
2a5c8DAAvidin/0.485
3nguADPNucleoside diphosphate kinase/0.485
1m78NDPDihydrofolate reductase1.5.1.30.483
3dhaC6LN-acyl homoserine lactonase AiiA3.1.1.810.483
1d8fSPIStromelysin-13.4.24.170.482
1j9zFADNADPH--cytochrome P450 reductase/0.482
2y60M8FIsopenicillin N synthase1.21.3.10.482
4mv8ACPBiotin carboxylase6.3.4.140.481
1gky5GPGuanylate kinase2.7.4.80.480
3vri1KXHLA class I histocompatibility antigen, B-57 alpha chain/0.480
1ia4TQ6Dihydrofolate reductase1.5.1.30.479
1mrqSTRAldo-keto reductase family 1 member C1/0.479
1q23FUAChloramphenicol acetyltransferase2.3.1.280.479
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.479
2wo7ASVIsopenicillin N synthase1.21.3.10.478
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
2zbaZBATrichothecene 3-O-acetyltransferase/0.477
3dys5GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.477
4eh8IRGMitogen-activated protein kinase 14/0.477
4fxy0W2Neurolysin, mitochondrial3.4.24.160.477
1bim0QBRenin3.4.23.150.475
1swnBTNStreptavidin/0.475
3dd0EZLCarbonic anhydrase 24.2.1.10.475
4qzuRTLRetinol-binding protein 2/0.475
1trkTPPTransketolase 12.2.1.10.474
2v3wTPPBenzoylformate decarboxylase4.1.1.70.474
3bi6396Wee1-like protein kinase2.7.10.20.474
3pahXDEPhenylalanine-4-hydroxylase1.14.16.10.474
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.474
1swdBTNStreptavidin/0.473
2ea4F79Methionine aminopeptidase 2/0.473
3nx2FERFerulic acid decarboxylase/0.473
1ldqSHMAvidin/0.472
2v13C40Renin3.4.23.150.472
1s36CEIObelin/0.471
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.471
3bw4FMNPutative 2-nitropropane dioxygenase/0.471
3dvaTPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.471
3dvaTPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.471
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
4bj9UHBTankyrase-22.4.2.300.471
4l1xNAPAldo-keto reductase family 1 member C2/0.471
4twnB96Ephrin type-A receptor 32.7.10.10.471
3c14FOKAdenylate cyclase type 2/0.470
3c14FOKAdenylate cyclase type 5/0.470
4kxjP34Nucleoprotein/0.470
1ghv120Prothrombin3.4.21.50.469
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.469
2aclL05Oxysterols receptor LXR-alpha/0.469
2y6fM9FIsopenicillin N synthase1.21.3.10.469
3d4bDZDNAD-dependent protein deacetylase/0.469
3t4hMD5Alpha-ketoglutarate-dependent dioxygenase AlkB1.14.11.330.469
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.469
4pnmNU1Tankyrase-22.4.2.300.469
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
3bgsDIHPurine nucleoside phosphorylase2.4.2.10.468
3mytEQUSteroid Delta-isomerase5.3.3.10.468
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.467
2flhZEACytokinin-specific binding protein/0.467
2fzbTOLAldose reductase1.1.1.210.467
2q3oFMN12-oxophytodienoate reductase 31.3.1.420.467
2rtlIMIStreptavidin/0.467
2zf051UProthrombin3.4.21.50.467
3k8q22APurine nucleoside phosphorylase2.4.2.10.467
8catNDPCatalase1.11.1.60.467
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.466
2zhw12UProthrombin3.4.21.50.466
3hk1B64Fatty acid-binding protein, adipocyte/0.466
3s8xE59Carbonic anhydrase 24.2.1.10.466
4yvbBTNStreptavidin/0.466
1dmyAZMCarbonic anhydrase 5A, mitochondrial4.2.1.10.465
1lnmDTXBilin-binding protein/0.465
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.465
2hveADPNucleoside diphosphate kinase A2.7.4.60.465
2r6kGTXGlutathione S-transferase A12.5.1.180.465
2r8pT6FTransketolase 1/0.465
3bjcWANcGMP-specific 3',5'-cyclic phosphodiesterase/0.465
3fhxPLPPyridoxal kinase2.7.1.350.465
4oex5EOcGMP-specific 3',5'-cyclic phosphodiesterase/0.465
1i8zINLCarbonic anhydrase 24.2.1.10.464
2oc9IMHPurine nucleoside phosphorylase2.4.2.10.464
3i1y33NBifunctional epoxide hydrolase 23.3.2.100.464
3maaFKPAdenylate cyclase type 2/0.464
3maaFKPAdenylate cyclase type 5/0.464
4c73TLH3-oxoacyl-ACP synthase/0.464
3sn6P0GBeta-2 adrenergic receptor/0.464
1ia1NDPDihydrofolate reductase1.5.1.30.463
1kt6RTLRetinol-binding protein 4/0.463
2aq7TL53-oxoacyl-[acyl-carrier-protein] synthase 12.3.1.410.463
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.463
3gluLYS_VAL_METNAD-dependent protein deacetylase sirtuin-3, mitochondrial3.5.10.463
4bb3KKAIsopenicillin N synthase1.21.3.10.463
5eccNAPDehydrofolate reductase type I/0.463
1rkpIBMcGMP-specific 3',5'-cyclic phosphodiesterase/0.462
2rbeZMGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
2xvhFADPutative flavin-containing monooxygenase/0.462
3aiqHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic3.2.1.1820.462
3pqbVGPPutative oxidoreductase/0.462
3saxE50Carbonic anhydrase 24.2.1.10.462
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
1zgv501Prothrombin3.4.21.50.461
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.461
3h3r14HCollagen type IV alpha-3-binding protein/0.461
4g2yNI5cGMP-specific 3',5'-cyclic phosphodiesterase/0.461
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.461
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.461
1d3dBZTProthrombin3.4.21.50.460
1d6w00RProthrombin3.4.21.50.460
1dliUDXUDP-glucose 6-dehydrogenase/0.460
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.460
1nceCB3Thymidylate synthase/0.460
2fvlNAPAldo-keto reductase family 1 member C41.1.1.2250.460
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3aosJH2Hemolymph juvenile hormone binding protein/0.460
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.459
2tohHBITyrosine 3-monooxygenase1.14.16.20.459
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.459
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.459
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3zv7NHGAcetylcholinesterase3.1.1.70.459
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.459
4bfwZVWPantothenate kinase2.7.1.330.459
4nhyPD2Prolyl 3-hydroxylase OGFOD11.14.110.459
4q0kGA3Phytohormone-binding protein/0.459
4uy6SAHHistidine N-alpha-methyltransferase/0.459
1axwMTXThymidylate synthase/0.458
1n0uSO1Elongation factor 2/0.458
1rx8FOLDihydrofolate reductase1.5.1.30.458
1s7gNADNAD-dependent protein deacylase 2/0.458
1yciNDFHypoxia-inducible factor 1-alpha inhibitor1.14.11.300.458
2bjuIH4Plasmepsin-23.4.23.390.458
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2rqfJH3Hemolymph juvenile hormone binding protein/0.458
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
3el7PD3Proto-oncogene tyrosine-protein kinase Src2.7.10.20.458
3iogSDFMetallo-beta-lactamase type 2/0.458
3lz6A0DCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
3oy0OY0Carbonic anhydrase 24.2.1.10.458
4avlTMPPolymerase acidic protein/0.458
4bqzGNPEctonucleoside triphosphate diphosphohydrolase 2/0.458
4dz5NAPAldo-keto reductase family 1 member C3/0.458
4eqrCOACoenzyme A disulfide reductase/0.458
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.458
4qemHC4Phospholipase A2 VRV-PL-VIIIa/0.458
1culFOKAdenylate cyclase type 2/0.457
1culFOKAdenylate cyclase type 5/0.457
1gveNAPAflatoxin B1 aldehyde reductase member 310.457
1hb3SCVIsopenicillin N synthase1.21.3.10.457
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2wehFB1Carbonic anhydrase 24.2.1.10.457
3ehjACPSensor histidine kinase DesK2.7.13.30.457
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.457
4askK0ILysine-specific demethylase 6B1.14.110.457
4g8bHL6Alpha/beta hydrolase fold protein/0.457
4gts7TPGeranylgeranyl transferase type-2 subunit beta2.5.1.600.457
4ivrN50Thymidine kinase/0.457
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.457
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.457
1a26CNAPoly [ADP-ribose] polymerase 12.4.2.300.456
1b3dS27Stromelysin-13.4.24.170.456
1bk0ACVIsopenicillin N synthase1.21.3.10.456
1blzACVIsopenicillin N synthase1.21.3.10.456
1m9nAMZBifunctional purine biosynthesis protein PURH2.1.2.30.456
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.456
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.456
3m98E02Carbonic anhydrase 24.2.1.10.456
3ntrNADInositol 2-dehydrogenase/D-chiro-inositol 3-dehydrogenase1.1.1.180.456
3oikWZBCarbonic anhydrase 24.2.1.10.456
3qpnPFKcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.456
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.456
4f0rMTA5-methylthioadenosine/S-adenosylhomocysteine deaminase/0.456
4qerSTLPhospholipase A2 VRV-PL-VIIIa/0.456
1hb1OCVIsopenicillin N synthase1.21.3.10.455
1ihiIU5Aldo-keto reductase family 1 member C2/0.455
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.455
1k22MELProthrombin3.4.21.50.455
1ly4COQDihydrofolate reductase1.5.1.30.455
1rszDIHPurine nucleoside phosphorylase2.4.2.10.455
1ycgFMNNitric oxide reductase10.455
1yqzCOACoenzyme A disulfide reductase/0.455
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.455
3gtcGTCBeta-lactamase3.5.2.60.455
3r0tFU9Casein kinase II subunit alpha2.7.11.10.455
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.455
4c6zTLE3-oxoacyl-ACP synthase/0.455
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.455
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.455
5cb3APRO-acetyl-ADP-ribose deacetylase/0.455
1fwkADPHomoserine kinase2.7.1.390.454
1kziTHGThymidylate synthase/0.454
1r2jFADFkbI/0.454
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.454
2vprTDCTetracycline repressor protein class H/0.454
3biy01KHistone acetyltransferase p300/0.454
3d7zGK5Mitogen-activated protein kinase 14/0.454
3h3qH13Collagen type IV alpha-3-binding protein/0.454
3nmpPYVAbscisic acid receptor PYL2/0.454
3rz8RZ8Carbonic anhydrase 24.2.1.10.454
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
3vhhVHHAvidin/0.454
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.454
4bf19FKCarbonic anhydrase 24.2.1.10.454
4hrqAZGCytidine and deoxycytidylate deaminase zinc-binding region/0.454
4rrfA3SThreonine--tRNA ligase6.1.1.30.454
1gj5130Prothrombin3.4.21.50.453
2bu9HFVIsopenicillin N synthase1.21.3.10.453
2gyuHI6Acetylcholinesterase3.1.1.70.453
2vo4GTB2,4-D inducible glutathione S-transferase/0.453
3g0yP9A3-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.453
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.453
4a81DXCMajor pollen allergen Bet v 1-A/0.453
4bamMM9Prothrombin3.4.21.50.453
4bb2STRCorticosteroid-binding globulin/0.453
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
4gyy12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.453
4rrmA3TProbable threonine--tRNA ligase 26.1.1.30.453
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
1dfoPLGSerine hydroxymethyltransferase2.1.2.10.452
1ni4TPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.452
1ni4TPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.452
1u1f183Uridine phosphorylase2.4.2.30.452
1uhhCZPAequorin-2/0.452
1ykdCMPAdenylate cyclase/0.452
2pksG44Prothrombin3.4.21.50.452
3h3t16HCollagen type IV alpha-3-binding protein/0.452
3ivcFG4Pantothenate synthetase6.3.2.10.452
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.452
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
1toxNADDiphtheria toxin/0.451
1yl7NAI4-hydroxy-tetrahydrodipicolinate reductase/0.451
2fzjDH3Dihydrofolate reductase1.5.1.30.451
2qw8NAPEugenol synthase 11.1.1.3180.451
2v5aLZLBiotin carboxylase6.3.4.140.451
2xlsFADPutative flavin-containing monooxygenase/0.451
3cgtBCDCyclomaltodextrin glucanotransferase2.4.1.190.451
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.451
3lq2TDPPyruvate dehydrogenase E1 component1.2.4.10.451
3myqE27Carbonic anhydrase 24.2.1.10.451
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.451
3qeoLLTDeoxycytidine kinase2.7.1.740.451
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.451
4bqyFNTEgl nine homolog 1/0.451
4lt63ATPoly(A) polymerase gamma2.7.7.190.451
4rrdA3TProbable threonine--tRNA ligase 26.1.1.30.451
1ia3TQ5Dihydrofolate reductase1.5.1.30.450
1jf0CZHObelin/0.450
1kceCB3Thymidylate synthase/0.450
1pq944BOxysterols receptor LXR-beta/0.450
1xp8AGSProtein RecA/0.450
2vqbFADPutative flavin-containing monooxygenase/0.450
2weoFBWCarbonic anhydrase 24.2.1.10.450
2zjwREFCasein kinase II subunit alpha2.7.11.10.450
3m2vCOMMethyl-coenzyme M reductase I subunit alpha2.8.4.10.450
4abzT1CTetracycline repressor protein class D/0.450
4bbyFADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.450
4dbs0HVAldo-keto reductase family 1 member C3/0.450
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.450
4js1CTNBeta-galactoside alpha-2,6-sialyltransferase 12.4.99.10.450
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
1jtqLY3Thymidylate synthase/0.449
1lelBH7Avidin/0.449
1mueCDDProthrombin3.4.21.50.449
1rxjBNIStreptavidin/0.449
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.449
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.449
3ho2N323-oxoacyl-[acyl-carrier-protein] synthase 22.3.1.1790.449
4bfzZVZPantothenate kinase2.7.1.330.449
4i4b1CV3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.449
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.449
4jzr4JREgl nine homolog 1/0.449
4qaiFMNNADPH dehydrogenase/0.449
4uugPXGBranched-chain amino acid aminotransferase, putative/0.449
4zu44TGWxcM-like protein/0.449
1i7pFADNADH-cytochrome b5 reductase 31.6.2.20.448
1iayAVG1-aminocyclopropane-1-carboxylate synthase 24.4.1.140.448
1tkaN3TTransketolase 12.2.1.10.448
1trgCB3Thymidylate synthase/0.448
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.448
2kceD16Thymidylate synthase/0.448
2zs8ADPPantothenate kinase2.7.1.330.448
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3p62FMNPentaerythritol tetranitrate reductase/0.448
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.448
3uxvGUNNADPH-dependent 7-cyano-7-deazaguanine reductase/0.448
4bfvZVVPantothenate kinase2.7.1.330.448
4d86ADPPoly [ADP-ribose] polymerase 142.4.2.300.448
4k6fNAPPutative Acetoacetyl-CoA reductase/0.448
5dbfNDPIridoid synthase1.3.1.990.448
1bwlFMNNADPH dehydrogenase 11.6.99.10.447
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.447
1h36R88Squalene--hopene cyclase4.2.1.1290.447
1me6IVSPlasmepsin-23.4.23.390.447
1obnASVIsopenicillin N synthase1.21.3.10.447
1ohkCOPDihydrofolate reductase1.5.1.30.447
1pu9COAHAT A1/0.447
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.447
1thnADPAnti-sigma F factor/0.447
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.447
2g5w8PG12-oxophytodienoate reductase 31.3.1.420.447
2jb4A14Isopenicillin N synthase1.21.3.10.447
2powI7CCarbonic anhydrase 24.2.1.10.447
2w6cBM4Acetylcholinesterase3.1.1.70.447
2w9hTOPDihydrofolate reductase1.5.1.30.447
2zi53L1Deoxycytidine kinase2.7.1.740.447
3dopNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.447
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3fhxPXLPyridoxal kinase2.7.1.350.447
4at3LTIBDNF/NT-3 growth factors receptor2.7.10.10.447
4cmfPXGUncharacterized protein/0.447
4fhd0TTSpore photoproduct lyase/0.447
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.447
4knjE1FCarbonic anhydrase 24.2.1.10.447
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.447
4wevSUZAldo-keto reductase family 1 member B101.1.10.447
5cmx0G6Prothrombin3.4.21.50.447
1ay0TPPTransketolase 12.2.1.10.446
1e2nRCAThymidine kinase/0.446
1h65GDPTranslocase of chloroplast 343.6.50.446
1kw8BPYBiphenyl-2,3-diol 1,2-dioxygenase1.13.11.390.446
1o1t2NHProtein farnesyltransferase subunit beta2.5.1.580.446
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.446
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.446
2hxzH7JCathepsin S3.4.22.270.446
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.446
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.446
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.446
2r2mI50Prothrombin3.4.21.50.446
2r8oT5XTransketolase 1/0.446
3dcwEZLCarbonic anhydrase 24.2.1.10.446
3ddw055Glycogen phosphorylase, liver form2.4.1.10.446
3exfTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.446
3exfTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.446
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.446
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.446
4a8v2ANMajor pollen allergen Bet v 1-J/0.446
4df2FMNNADPH dehydrogenase/0.446
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4eqsCOACoenzyme A disulfide reductase/0.446
4f3gKAIGlutamate receptor 3/0.446
1a8t061Metallo-beta-lactamase type 2/0.445
1h63FMNPentaerythritol tetranitrate reductase/0.445
1ngsTPPTransketolase 12.2.1.10.445
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.445
2nmtMIMGlycylpeptide N-tetradecanoyltransferase2.3.1.970.445
2vmyFFOSerine hydroxymethyltransferase/0.445
3bw2FMNPutative 2-nitropropane dioxygenase/0.445
3dccD9ZCarbonic anhydrase 24.2.1.10.445
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3gxfIFMGlucosylceramidase3.2.1.450.445
3iexGMPPurine nucleoside phosphorylase/0.445
3m96E38Carbonic anhydrase 24.2.1.10.445
4araC56Acetylcholinesterase3.1.1.70.445
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.445
5emhNAPIridoid synthase1.3.1.990.445
5hwrCOAHydroxymethylglutaryl-CoA synthase/0.445
1dr3TAPDihydrofolate reductase1.5.1.30.444
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1lqaNDPProtein tas/0.444
1nzq162Prothrombin3.4.21.50.444
1rr6IMHPurine nucleoside phosphorylase2.4.2.10.444
1x2bSTXProline iminopeptidase3.4.11.50.444
2j2pSC2Ficolin-2/0.444
2x6o2TCTetracycline repressor protein class D/0.444
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.444
3havATPAminoglycoside phosphotransferase/0.444
3k4nFADPyranose 2-oxidase/0.444
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.444
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
4b63NAPL-ornithine N(5)-monooxygenase/0.444
4blcNDPCatalase1.11.1.60.444
4dpy2P0Mevalonate diphosphate decarboxylase/0.444
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.444
5pahLDPPhenylalanine-4-hydroxylase1.14.16.10.444
1ex75GPGuanylate kinase2.7.4.80.443
1fncFDAFerredoxin--NADP reductase, chloroplastic1.18.1.20.443
1g28FMNPHY3/0.443
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.443
1okmSABCarbonic anhydrase 24.2.1.10.443
2bxmIMNSerum albumin/0.443
2r5nTPPTransketolase 1/0.443
3bv7NAP3-oxo-5-beta-steroid 4-dehydrogenase/0.443
3hgsFMN12-oxophytodienoate reductase 31.3.1.420.443
4b1rITCTetracycline repressor protein class D/0.443
4bftZVTPantothenate kinase2.7.1.330.443
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.443
4ckcSAHmRNA-capping enzyme catalytic subunit2.1.1.560.443
4h0vNADIota toxin component Ia/0.443
4jtrIBPAldo-keto reductase family 1 member C2/0.443
4ly91YYGlucokinase regulatory protein/0.443
4pahLNRPhenylalanine-4-hydroxylase1.14.16.10.443
4phlPILPhosphodiesterase/0.443
1f20FADNitric oxide synthase, brain1.14.13.390.442
1nbiSAMGlycine N-methyltransferase2.1.1.200.442
1qk35GPHypoxanthine-guanine-xanthine phosphoribosyltransferase2.4.2.220.442
1txtCAAHMG-CoA synthase/0.442
1ygjRMCPyridoxal kinase2.7.1.350.442
1z71L17Prothrombin3.4.21.50.442
1z7yAA5Cysteine synthase 12.5.1.470.442
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.442
2c6c24IGlutamate carboxypeptidase 23.4.17.210.442
2fg5GNPRas-related protein Rab-31/0.442
2ftoCB3Thymidylate synthase/0.442
2iviACWIsopenicillin N synthase1.21.3.10.442
2vkeTACTetracycline repressor protein class D/0.442
2w3mFOLDihydrofolate reductase1.5.1.30.442
2w6pOA4Biotin carboxylase6.3.4.140.442
2wyaHMGHydroxymethylglutaryl-CoA synthase, mitochondrial2.3.3.100.442
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.442
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
3v1uHXC3-oxoacyl-(Acyl-carrier-protein) reductase/0.442
4acuQN7Beta-secretase 13.4.23.460.442
4at0FADPossible succinate dehydrogenase/0.442
4b64NAPL-ornithine N(5)-monooxygenase/0.442
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.442
4kwhNAPReductase homolog/0.442
4n3l2FNProthrombin3.4.21.50.442
4wecNADShort chain dehydrogenase/0.442
4xq9NADHomospermidine synthase2.5.1.440.442
4yp5NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.442
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.442
5stdUNNScytalone dehydratase4.2.1.940.442
1beuIPLTryptophan synthase alpha chain/0.441
1cjvFOKAdenylate cyclase type 2/0.441
1cjvFOKAdenylate cyclase type 5/0.441
1cnfFADNitrate reductase [NADH]1.7.1.10.441
1h74ADPHomoserine kinase2.7.1.390.441
1i75NOJCyclomaltodextrin glucanotransferase2.4.1.190.441
1kqoDNDNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.441
1kt3RTLRetinol-binding protein 4/0.441
1t4v14AProthrombin3.4.21.50.441
1uzwCDHIsopenicillin N synthase1.21.3.10.441
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2a57CRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
2c1zU2FAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.441
2hejNDPAldo-keto reductase family 1 member C211.1.10.441
2r0pK2CPutative FAD-monooxygenase/0.441
2uupLK4UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.441
3b9xNOSPyrimidine-specific ribonucleoside hydrolase RihB3.2.2.80.441
3c27DKKProthrombin3.4.21.50.441
3d3p20AcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.441
3d84NDPDihydrofolate reductase1.5.1.30.441
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
3hxdBD7Geranylgeranyl transferase type-2 subunit beta2.5.1.600.441
3ipkPMSSurface protein adhesin/0.441
3ix3OHNTranscriptional activator protein LasR/0.441
3vyfVYFRenin3.4.23.150.441
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4jbxSK7Thymidine kinase/0.441
4jq4IMNAldo-keto reductase family 1 member C2/0.441
5agyGTBTau class glutathione S-transferase/0.441
5c3rHMUThymine dioxygenase/0.441
5cc9DDFDihydrofolate reductase1.5.1.30.441
5fltVJJCarbonic anhydrase 24.2.1.10.441
5iqbGNPBifunctional AAC/APH2.3.10.441
5p2pDHGPhospholipase A2, major isoenzyme3.1.1.40.441
1amoFADNADPH--cytochrome P450 reductase/0.440
1kt7RTLRetinol-binding protein 4/0.440
1lvu9PPPurine nucleoside phosphorylase2.4.2.10.440
1pqc444Oxysterols receptor LXR-beta/0.440
2ab8MTPAdenosine kinase2.7.1.200.440
2bdyUNBProthrombin3.4.21.50.440
2bjsACVIsopenicillin N synthase1.21.3.10.440
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.440
2fbwCBESuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.440
2fbwCBESuccinate dehydrogenase cytochrome b, large subunit/0.440
2hl2SSAThreonine--tRNA ligase6.1.1.30.440
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.440
2ow9SP6Collagenase 33.4.240.440
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.440
2x06NADL-sulfolactate dehydrogenase/0.440
2x9dITCTetracycline repressor protein class D/0.440
2yphQQY2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.440
3c15FOKAdenylate cyclase type 2/0.440
3c15FOKAdenylate cyclase type 5/0.440
3fznD7KBenzoylformate decarboxylase4.1.1.70.440
3kigDA4Carbonic anhydrase 24.2.1.10.440
3own3OXRenin3.4.23.150.440
3q43D66M1 family aminopeptidase3.4.110.440
3q7fED2Uncharacterized protein/0.440
3rl45GPMetallophosphoesterase MPPED23.10.440
4a802ANMajor pollen allergen Bet v 1-A/0.440
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4baqM4ZProthrombin3.4.21.50.440
4dvi2IWTankyrase-12.4.2.300.440
5e5h0T1Succinyl-CoA:acetate CoA-transferase/0.440