Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
PDB ID | HET | Uniprot Name | EC Number |
---|---|---|---|
2q5y | TYR_GLY_LEU | Nuclear pore complex protein Nup98-Nup96 |
PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
---|---|---|---|---|---|
2q5y | TYR_GLY_LEU | Nuclear pore complex protein Nup98-Nup96 | / | 1.000 | |
3kkz | SAM | Uncharacterized protein | / | 0.511 | |
1g63 | FMN | Epidermin decarboxylase | 4.1.1 | 0.503 | |
1m9j | CLW | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.500 | |
1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.496 | |
3cvk | N34 | Genome polyprotein | 2.7.7.48 | 0.495 | |
3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.495 | |
4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.494 | |
2pch | SAH | Diphthine synthase | / | 0.493 | |
4j0v | 1H7 | Beta-secretase 1 | 3.4.23.46 | 0.493 | |
3sxj | SAM | Putative methyltransferase | / | 0.492 | |
2g1n | 1IG | Renin | 3.4.23.15 | 0.491 | |
2g1r | 3IG | Renin | 3.4.23.15 | 0.491 | |
2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.490 | |
3g0y | P9A | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.490 | |
2g1y | 5IG | Renin | 3.4.23.15 | 0.489 | |
4i10 | 1BS | Beta-secretase 1 | 3.4.23.46 | 0.488 | |
4q0k | GA3 | Phytohormone-binding protein | / | 0.487 | |
2e07 | SAH | Diphthine synthase | / | 0.486 | |
2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.485 | |
3t7s | SAM | Uncharacterized protein | / | 0.485 | |
4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.484 | |
4isg | 1FY | Glucokinase | 2.7.1.2 | 0.482 | |
2g1s | 4IG | Renin | 3.4.23.15 | 0.481 | |
3g5m | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.478 | |
3phj | DHK | Shikimate dehydrogenase (NADP(+)) | / | 0.478 | |
1siq | FAD | Glutaryl-CoA dehydrogenase, mitochondrial | 1.3.8.6 | 0.477 | |
5c1d | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.477 | |
1v48 | HA1 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.476 | |
2dv4 | SAH | Diphthine synthase | / | 0.476 | |
1cne | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.475 | |
1x1b | SAH | C-20 methyltransferase | / | 0.475 | |
3nut | SAH | Precorrin-3 methylase | / | 0.475 | |
2cnd | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.474 | |
2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.474 | |
3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.474 | |
2bdz | E64 | Mexicain | 3.4.22 | 0.473 | |
2iku | LIY | Renin | 3.4.23.15 | 0.473 | |
3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.473 | |
1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.472 | |
1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.472 | |
1wng | SAH | Diphthine synthase | / | 0.472 | |
2aou | CQA | Histamine N-methyltransferase | 2.1.1.8 | 0.472 | |
2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.472 | |
2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.472 | |
2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.472 | |
4dch | 4DC | Glucokinase | 2.7.1.2 | 0.472 | |
4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.472 | |
1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.471 | |
2hux | SAH | Diphthine synthase | / | 0.471 | |
2qmy | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.471 | |
3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.471 | |
3vyf | VYF | Renin | 3.4.23.15 | 0.471 | |
4dro | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.471 | |
4qfz | TTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.471 | |
3ske | 054 | Genome polyprotein | 2.7.7.48 | 0.470 | |
4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.470 | |
4imf | SI3 | N-acetylneuraminate lyase | / | 0.470 | |
1a59 | COA | 2-methylcitrate synthase | / | 0.469 | |
1iki | REY | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.469 | |
1uvs | I11 | Prothrombin | 3.4.21.5 | 0.469 | |
2hr8 | SAH | Diphthine synthase | / | 0.469 | |
2pci | SAH | Diphthine synthase | / | 0.469 | |
2pcm | SAH | Diphthine synthase | / | 0.469 | |
3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.469 | |
1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.468 | |
2el0 | SAH | Diphthine synthase | / | 0.468 | |
3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
3tg4 | SAM | N-lysine methyltransferase SMYD2 | / | 0.468 | |
4fw0 | 5KJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.468 | |
4nbt | NAD | 3-oxoacyl-[acyl-carrier-protein] reductase | / | 0.468 | |
1e1q | ANP | ATP synthase subunit alpha, mitochondrial | / | 0.467 | |
1e1q | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.467 | |
1yqs | BSA | D-alanyl-D-alanine carboxypeptidase | 3.4.16.4 | 0.467 | |
2bn4 | FMN | NADPH--cytochrome P450 reductase | / | 0.467 | |
3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.467 | |
3exo | 5MS | Beta-secretase 1 | 3.4.23.46 | 0.467 | |
5ao1 | DG3 | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.467 | |
1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.466 | |
2ejz | SAH | Diphthine synthase | / | 0.466 | |
2g24 | 7IG | Renin | 3.4.23.15 | 0.466 | |
3ngq | 1PS | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.466 | |
3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.466 | |
4b68 | FAD | L-ornithine N(5)-monooxygenase | / | 0.466 | |
1m9m | 6NI | Nitric oxide synthase, endothelial | 1.14.13.39 | 0.465 | |
2hut | SAH | Diphthine synthase | / | 0.465 | |
2p9d | SAH | Diphthine synthase | / | 0.465 | |
2z95 | NDP | GDP-mannose 4,6-dehydratase | / | 0.465 | |
3ho2 | N32 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.465 | |
1e79 | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.464 | |
1e79 | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
1h8h | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.464 | |
1h8h | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.464 | |
1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.464 | |
2fut | H1S | Heparin and heparin-sulfate lyase | / | 0.464 | |
3bk2 | U5P | Ribonuclease J | / | 0.464 | |
3h2l | YAK | Genome polyprotein | 2.7.7.48 | 0.464 | |
4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.464 | |
1vce | SAH | Diphthine synthase | / | 0.463 | |
2a58 | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.463 | |
2eh4 | SAH | Diphthine synthase | / | 0.463 | |
2eld | SAH | Diphthine synthase | / | 0.463 | |
2gfx | PMN | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.463 | |
3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.463 | |
3jus | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.463 | |
3kn0 | 3TO | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.463 | |
4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.463 | |
2dxv | SAH | Diphthine synthase | / | 0.462 | |
2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.462 | |
2vpr | TDC | Tetracycline repressor protein class H | / | 0.462 | |
2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
3h2s | NDP | Putative NADH-flavin reductase | / | 0.462 | |
3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.462 | |
3ljg | EEF | Macrophage metalloelastase | 3.4.24.65 | 0.462 | |
3uzz | ASD | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
5ex0 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.462 | |
1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
1uam | SAH | tRNA (guanine-N(1)-)-methyltransferase | 2.1.1.228 | 0.461 | |
1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.461 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.461 | |
2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.461 | |
2yye | APC | Selenide, water dikinase | 2.7.9.3 | 0.461 | |
3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.461 | |
4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.461 | |
1f20 | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
1ja1 | FMN | NADPH--cytochrome P450 reductase | / | 0.460 | |
1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.460 | |
2dsi | SAH | Diphthine synthase | / | 0.460 | |
2xfk | AA9 | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.460 | |
3uxe | 465 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.460 | |
4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.460 | |
4dus | 0MP | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
4jic | FMN | GTN Reductase | / | 0.460 | |
4rxq | DUT | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.460 | |
5kwv | ANP | Pantothenate synthetase | / | 0.460 | |
1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
2jk6 | FAD | Trypanothione reductase | / | 0.459 | |
2rbe | ZMG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
3d64 | NAD | Adenosylhomocysteinase | / | 0.459 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.459 | |
3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.459 | |
4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.459 | |
4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.459 | |
1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.458 | |
2ed3 | SAH | Diphthine synthase | / | 0.458 | |
2y37 | A54 | Nitric oxide synthase, inducible | 1.14.13.39 | 0.458 | |
3gwf | NAP | Cyclohexanone monooxygenase | / | 0.458 | |
3zvm | ADP | Bifunctional polynucleotide phosphatase/kinase | 2.7.1.78 | 0.458 | |
4bmp | FMN | Protein NrdI | / | 0.458 | |
1x27 | ASP_TYR_VAL_HIS_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.457 | |
2bf4 | FAD | NADPH--cytochrome P450 reductase | / | 0.457 | |
2egb | SAH | Diphthine synthase | / | 0.457 | |
2fzm | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.457 | |
2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.457 | |
3tfu | PL8 | Adenosylmethionine-8-amino-7-oxononanoate aminotransferase | 2.6.1.62 | 0.457 | |
4k4f | K4F | Tankyrase-1 | 2.4.2.30 | 0.457 | |
1amo | FMN | NADPH--cytochrome P450 reductase | / | 0.456 | |
1qoq | IGP | Tryptophan synthase alpha chain | / | 0.456 | |
2a2c | ADP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.456 | |
2e8u | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.456 | |
2eh5 | SAH | Diphthine synthase | / | 0.456 | |
2p6l | SAH | Diphthine synthase | / | 0.456 | |
2vo7 | M05 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.456 | |
3ing | NDP | Homoserine dehydrogenase related protein | / | 0.456 | |
3t3q | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.456 | |
3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.456 | |
4y3q | F02 | Endothiapepsin | 3.4.23.22 | 0.456 | |
4yqf | GDP | Septin-9 | / | 0.456 | |
5a9s | NAP | Putative dehydrogenase | / | 0.456 | |
1j1z | ATP | Argininosuccinate synthase | / | 0.455 | |
1tj1 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.455 | |
1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.455 | |
3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
3huc | G97 | Mitogen-activated protein kinase 14 | / | 0.455 | |
3i8p | 840 | 3-oxoacyl-[acyl-carrier-protein] synthase 2 | 2.3.1.179 | 0.455 | |
3udk | 095 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
4b05 | 32D | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
5fe1 | 12Q | Histone acetyltransferase KAT2B | 2.3.1.48 | 0.455 | |
1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.454 | |
2dv3 | SAH | Diphthine synthase | / | 0.454 | |
2e8h | SAH | Diphthine synthase | / | 0.454 | |
2il2 | LIX | Renin | 3.4.23.15 | 0.454 | |
2qe2 | 452 | Polyprotein | / | 0.454 | |
3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
3swc | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.454 | |
3ziu | LSS | Leucyl-tRNA synthetase | / | 0.454 | |
4fox | UMP | Thymidylate synthase ThyA | / | 0.454 | |
3vw7 | VPX | Proteinase-activated receptor 1 | / | 0.454 | |
1cnf | FAD | Nitrate reductase [NADH] | 1.7.1.1 | 0.453 | |
1g6k | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.453 | |
1i75 | NOJ | Cyclomaltodextrin glucanotransferase | 2.4.1.19 | 0.453 | |
1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
2c20 | NAD | UDP-glucose 4-epimerase | / | 0.453 | |
2dsh | SAH | Diphthine synthase | / | 0.453 | |
2e08 | SAH | Diphthine synthase | / | 0.453 | |
2e15 | SAH | Diphthine synthase | / | 0.453 | |
2g1o | 2IG | Renin | 3.4.23.15 | 0.453 | |
2g22 | 6IG | Renin | 3.4.23.15 | 0.453 | |
2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.453 | |
2xve | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.453 | |
3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.453 | |
3keq | NAD | Redox-sensing transcriptional repressor Rex | / | 0.453 | |
4bfd | 8T3 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
4h3i | 10V | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
4psb | GA3 | Cytokinin-specific binding protein | / | 0.453 | |
5dv2 | C5P | CCR4-NOT transcription complex subunit 6-like | 3.1.13.4 | 0.453 | |
1gvr | TNL | Pentaerythritol tetranitrate reductase | / | 0.452 | |
1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.452 | |
1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.452 | |
1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.452 | |
2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
2e17 | SAH | Diphthine synthase | / | 0.452 | |
2g21 | L1B | Renin | 3.4.23.15 | 0.452 | |
3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.452 | |
4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.452 | |
4ih7 | 1ER | Genome polyprotein | 2.7.7.48 | 0.452 | |
4ise | 1FW | Glucokinase | 2.7.1.2 | 0.452 | |
4ype | SAM | Histone-lysine N-methyltransferase ASH1L | 2.1.1.43 | 0.452 | |
1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.451 | |
1kfb | IGP | Tryptophan synthase alpha chain | / | 0.451 | |
1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
1w0k | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.451 | |
1w0k | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.451 | |
2egl | SAH | Diphthine synthase | / | 0.451 | |
2wxv | WXV | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.451 | |
2z6r | SAH | Diphthine synthase | / | 0.451 | |
3a26 | MTA | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.451 | |
3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.451 | |
3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.451 | |
3ox3 | 4X4 | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.451 | |
3vyd | VYD | Renin | 3.4.23.15 | 0.451 | |
4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
4i0f | 1BF | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
5hq8 | SAH | Histone-lysine N-methyltransferase SMYD3 | 2.1.1.43 | 0.451 | |
2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.450 | |
2huq | SAH | Diphthine synthase | / | 0.450 | |
2pca | SAH | Diphthine synthase | / | 0.450 | |
2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
2y5h | Y5H | Coagulation factor X | 3.4.21.6 | 0.450 | |
3a25 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.450 | |
3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.450 | |
3rfa | SAM | Dual-specificity RNA methyltransferase RlmN | / | 0.450 | |
4g8j | THM | Uridine phosphorylase | / | 0.450 | |
4j3m | AJ8 | Tankyrase-2 | 2.4.2.30 | 0.450 | |
4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.450 | |
5fsi | 8DG | 7,8-dihydro-8-oxoguanine triphosphatase | 3.6.1.55 | 0.450 | |
1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.449 | |
1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.449 | |
1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
2a2d | ANP | N-acetylgalactosamine kinase | 2.7.1.157 | 0.449 | |
2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.449 | |
2owv | SAH | Diphthine synthase | / | 0.449 | |
2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.449 | |
2zvb | SAH | Precorrin-3 C17-methyltransferase | / | 0.449 | |
3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
3oqk | S52 | Renin | 3.4.23.15 | 0.449 | |
3pm1 | ET | HTH-type transcriptional regulator QacR | / | 0.449 | |
1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.448 | |
1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.448 | |
1kw9 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.448 | |
2dsg | SAH | Diphthine synthase | / | 0.448 | |
2eg5 | SAH | 7-methylxanthosine synthase 1 | / | 0.448 | |
2emr | SAH | Diphthine synthase | / | 0.448 | |
2owf | SAH | Diphthine synthase | / | 0.448 | |
2uzv | SS5 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.448 | |
2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.448 | |
2wea | PP6 | Penicillopepsin-1 | 3.4.23.20 | 0.448 | |
2xvh | FAD | Putative flavin-containing monooxygenase | / | 0.448 | |
2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.448 | |
3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.448 | |
3t64 | DU3 | Deoxyuridine 5'-triphosphate nucleotidohydrolase | / | 0.448 | |
3tfy | MET_LEU_GLY_PRO | N-alpha-acetyltransferase 50 | 2.3.1 | 0.448 | |
3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.448 | |
4df2 | FMN | NADPH dehydrogenase | / | 0.448 | |
4djy | 0KR | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
4ke0 | 1R8 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
4zj8 | SUV | Orexin receptor type 1 | / | 0.448 | |
1bil | 0IU | Renin | 3.4.23.15 | 0.447 | |
1k7f | IAV | Tryptophan synthase alpha chain | / | 0.447 | |
2ovm | AS0 | Progesterone receptor | / | 0.447 | |
2ql6 | TIZ | Nicotinamide riboside kinase 1 | / | 0.447 | |
2r8o | T5X | Transketolase 1 | / | 0.447 | |
2r8p | T6F | Transketolase 1 | / | 0.447 | |
2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.447 | |
3gnw | XNC | Genome polyprotein | 2.7.7.48 | 0.447 | |
3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.447 | |
3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.447 | |
3uzx | AOX | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.447 | |
4aa4 | QC0 | Mitogen-activated protein kinase 14 | / | 0.447 | |
4e2b | FMN | Dehydrogenase | / | 0.447 | |
4jsg | Q10 | Nitric oxide synthase, brain | 1.14.13.39 | 0.447 | |
4msg | 2C6 | Tankyrase-1 | 2.4.2.30 | 0.447 | |
4djh | JDC | Kappa-type opioid receptor | / | 0.447 | |
1a9c | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.446 | |
1by5 | GLY_GLY_GLY_AHO_AHO_AHO_FE | Ferrichrome-iron receptor | / | 0.446 | |
1ez0 | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.446 | |
1fxu | GU7 | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
1yry | MSG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.446 | |
2b4t | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
2bf4 | FMN | NADPH--cytochrome P450 reductase | / | 0.446 | |
2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
2fs4 | PZ1 | Renin | 3.4.23.15 | 0.446 | |
2owg | SAH | Diphthine synthase | / | 0.446 | |
3faz | NOS | Purine nucleoside phosphorylase | / | 0.446 | |
3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.446 | |
3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.446 | |
3hlw | CE3 | Beta-lactamase | / | 0.446 | |
3kmt | SAH | Histone H3K27 methylase | / | 0.446 | |
3nd6 | ATP | Phosphopantetheine adenylyltransferase | / | 0.446 | |
3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
3uic | 09T | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.446 | |
4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.446 | |
4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
4jxr | ACO | Acetyltransferase | / | 0.446 | |
4kxj | P34 | Nucleoprotein | / | 0.446 | |
4qof | FMN | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.446 | |
5eio | NAP | [LysW]-L-2-aminoadipate 6-phosphate reductase | / | 0.446 | |
1jdz | FMB | Purine nucleoside phosphorylase | / | 0.445 | |
1lvu | 9PP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
1m9t | INE | Nitric oxide synthase, inducible | 1.14.13.39 | 0.445 | |
2e8q | SAH | Diphthine synthase | / | 0.445 | |
2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.445 | |
3hdy | GDU | UDP-galactopyranose mutase | / | 0.445 | |
3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.445 | |
3myt | EQU | Steroid Delta-isomerase | 5.3.3.1 | 0.445 | |
4bqu | CLR | Japanin | / | 0.445 | |
4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.445 | |
4yj2 | GTP | Tubulin alpha-1B chain | / | 0.445 | |
5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.445 | |
1pfy | MSP | Methionine--tRNA ligase | 6.1.1.10 | 0.444 | |
1uh5 | TCL | Enoyl-ACP reductase | / | 0.444 | |
2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.444 | |
2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.444 | |
2egs | SAH | Diphthine synthase | / | 0.444 | |
2ek3 | SAH | Diphthine synthase | / | 0.444 | |
2iko | 7IG | Renin | 3.4.23.15 | 0.444 | |
2owk | SAH | Diphthine synthase | / | 0.444 | |
2pia | FMN | Phthalate dioxygenase reductase | / | 0.444 | |
2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.444 | |
2v57 | PRL | TetR family transcriptional regulator | / | 0.444 | |
2wat | COA | Fatty acid synthase subunit alpha | 2.3.1.86 | 0.444 | |
2z7h | GG3 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
3btj | DEQ | HTH-type transcriptional regulator QacR | / | 0.444 | |
3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.444 | |
3lnc | 5GP | Guanylate kinase | / | 0.444 | |
3s8p | SAM | Histone-lysine N-methyltransferase KMT5B | 2.1.1.43 | 0.444 | |
3sfh | 1DI | Histone deacetylase 8 | 3.5.1.98 | 0.444 | |
4emd | C5P | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.444 | |
4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
4rlh | 0WE | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.444 | |
4zwp | M44 | Xaa-Pro dipeptidase | 3.4.13.9 | 0.444 | |
5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.444 | |
1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.443 | |
1cjv | DAD | Adenylate cyclase type 2 | / | 0.443 | |
1cjv | DAD | Adenylate cyclase type 5 | / | 0.443 | |
1j9z | FAD | NADPH--cytochrome P450 reductase | / | 0.443 | |
1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
1kbo | 340 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
1pag | FMP | Antiviral protein I | 3.2.2.22 | 0.443 | |
1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.443 | |
1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.443 | |
1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.443 | |
1utt | CP8 | Macrophage metalloelastase | 3.4.24.65 | 0.443 | |
2ehl | SAH | Diphthine synthase | / | 0.443 | |
2ele | SAH | Diphthine synthase | / | 0.443 | |
2g20 | L1A | Renin | 3.4.23.15 | 0.443 | |
2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
2owu | SAH | Diphthine synthase | / | 0.443 | |
2qw0 | 34Z | 4-chlorobenzoyl CoA ligase | / | 0.443 | |
2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.443 | |
2vcx | D26 | Hematopoietic prostaglandin D synthase | / | 0.443 | |
2y02 | WHJ | Beta-1 adrenergic receptor | / | 0.443 | |
2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.443 | |
3bj8 | COA | Diamine acetyltransferase 1 | / | 0.443 | |
3kc3 | MK2 | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.443 | |
3o7b | SAH | Ribosomal RNA small subunit methyltransferase Nep1 | / | 0.443 | |
3ooi | SAM | Histone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific | 2.1.1.43 | 0.443 | |
3r8h | ZOM | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.443 | |
4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.443 | |
4m48 | 21B | Sodium-dependent dopamine transporter | / | 0.443 | |
4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.443 | |
4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.443 | |
4ra3 | TFX | Beta-2-microglobulin | / | 0.443 | |
4zvl | FAD | Ribosyldihydronicotinamide dehydrogenase [quinone] | / | 0.443 | |
5e7o | MD1 | DMSO reductase family type II enzyme, molybdopterin subunit | / | 0.443 | |
1aa6 | MGD | Formate dehydrogenase H | 1.1.99.33 | 0.442 | |
1eii | RTL | Retinol-binding protein 2 | / | 0.442 | |
1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.442 | |
2cft | PLP | Pyridoxal phosphate phosphatase | / | 0.442 | |
2ed4 | NAD | 4-hydroxyphenylacetate 3-monooxygenase reductase component | 1.5.1.36 | 0.442 | |
2eni | SAH | Diphthine synthase | / | 0.442 | |
2g9r | G27 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.442 | |
2rfi | SAH | Histone-lysine N-methyltransferase EHMT1 | / | 0.442 | |
2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.442 | |
3c16 | FOK | Adenylate cyclase type 2 | / | 0.442 | |
3c16 | FOK | Adenylate cyclase type 5 | / | 0.442 | |
3g0b | T22 | Dipeptidyl peptidase 4 | / | 0.442 | |
3g5k | BB2 | Peptide deformylase, mitochondrial | 3.5.1.88 | 0.442 | |
3l9l | L9L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.442 | |
3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
3zhy | FM6 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.442 | |
4bti | 7R9 | Coagulation factor X | 3.4.21.6 | 0.442 | |
4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4drp | 0MD | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.442 | |
4isf | 1FX | Glucokinase | 2.7.1.2 | 0.442 | |
4j1k | 1HG | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
4ozt | P1A | Ecdysone receptor, putative | / | 0.442 | |
4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.442 | |
4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.442 | |
4z5w | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.442 | |
5cho | FAD | Flavin reductase | / | 0.442 | |
5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
1oya | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.441 | |
1p2a | 5BN | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
1qti | GNT | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
1qx4 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.441 | |
1txt | CAA | HMG-CoA synthase | / | 0.441 | |
1yum | NCN | Probable nicotinate-nucleotide adenylyltransferase | 2.7.7.18 | 0.441 | |
2dxw | SAH | Diphthine synthase | / | 0.441 | |
2ed5 | SAH | Diphthine synthase | / | 0.441 | |
2flh | ZEA | Cytokinin-specific binding protein | / | 0.441 | |
2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.441 | |
2gd6 | ACO | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.441 | |
2gtb | AZP | Orf1ab polyprotein | / | 0.441 | |
2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
2ifa | FMN | Uncharacterized protein | / | 0.441 | |
2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.441 | |
2p2x | SAH | Diphthine synthase | / | 0.441 | |
2xuh | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
2zda | 32U | Prothrombin | 3.4.21.5 | 0.441 | |
3c74 | ANU | Uridine phosphorylase | 2.4.2.3 | 0.441 | |
3cls | FAD | Electron transfer flavoprotein subunit alpha | / | 0.441 | |
3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.441 | |
3kxw | 1ZZ | Saframycin Mx1 synthetase B | / | 0.441 | |
3o9l | LPN | Renin | 3.4.23.15 | 0.441 | |
3qgi | 33F | Genome polyprotein | 2.7.7.48 | 0.441 | |
3qvi | K95 | HAP protein | / | 0.441 | |
3rbq | GLY_ALA_GLY_DAO | Protein unc-119 homolog A | / | 0.441 | |
3uph | 0C1 | Genome polyprotein | 2.7.7.48 | 0.441 | |
3wtk | TH4 | Acetylcholine-binding protein | / | 0.441 | |
3zks | WZV | Beta-secretase 2 | 3.4.23.45 | 0.441 | |
4acx | S8Z | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
4e2d | FMN | Dehydrogenase | / | 0.441 | |
4j0z | 1H5 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
4lwb | QJ8 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.441 | |
4ug9 | 1EW | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.441 | |
4xr9 | NAD | CalS8 | / | 0.441 | |
1ix1 | BB2 | Peptide deformylase | / | 0.440 | |
1mu6 | CDA | Prothrombin | 3.4.21.5 | 0.440 | |
1pjc | NAD | Alanine dehydrogenase | / | 0.440 | |
1r00 | SAH | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.440 | |
1umk | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.440 | |
1x1a | SAM | C-20 methyltransferase | / | 0.440 | |
1zzr | DP9 | Nitric oxide synthase, brain | 1.14.13.39 | 0.440 | |
2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.440 | |
2bkt | RPF | Renin | 3.4.23.15 | 0.440 | |
2ejj | SAH | Diphthine synthase | / | 0.440 | |
2ien | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.440 | |
2nq7 | HM5 | Methionine aminopeptidase 1 | / | 0.440 | |
2op9 | WR1 | Orf1ab polyprotein | / | 0.440 | |
2reh | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.440 | |
2x91 | LPR | Angiotensin-converting enzyme | 3.4.15.1 | 0.440 | |
2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
2zw5 | COA | Bleomycin acetyltransferase | / | 0.440 | |
3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.440 | |
3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.440 | |
3bht | MFR | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.440 | |
3egk | M18 | Prothrombin | 3.4.21.5 | 0.440 | |
3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
3h5s | H5S | Genome polyprotein | 2.7.7.48 | 0.440 | |
3u8l | 09Q | Acetylcholine-binding protein | / | 0.440 | |
4b1f | KRH | Glutamate racemase | / | 0.440 | |
4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.440 | |
4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.440 | |
4j53 | 1J4 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.440 |