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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.25

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.251.000
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.547
4f081RSTyrosine-protein kinase JAK2/0.542
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.541
2pvlP55Casein kinase II subunit alpha2.7.11.10.540
2pvhP19Casein kinase II subunit alpha2.7.11.10.538
4aqc88ATyrosine-protein kinase JAK2/0.531
1m2pHNACasein kinase II subunit alpha2.7.11.10.530
2pvnP63Casein kinase II subunit alpha2.7.11.10.530
1g5sI17Cyclin-dependent kinase 22.7.11.220.527
3be9P04Casein kinase II subunit alpha2.7.11.10.526
3le62BZCyclin-dependent kinase 22.7.11.220.525
4e6d0NUTyrosine-protein kinase JAK2/0.525
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.524
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.524
3iok1P6Tyrosine-protein kinase JAK2/0.524
1eh4IC1Casein kinase I homolog 12.7.11.10.523
1m2rMNYCasein kinase II subunit alpha2.7.11.10.521
4y93746Tyrosine-protein kinase/0.521
1ke7LS3Cyclin-dependent kinase 22.7.11.220.519
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.519
1ke6LS2Cyclin-dependent kinase 22.7.11.220.517
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.517
3rvg17PTyrosine-protein kinase JAK2/0.516
4hge15VTyrosine-protein kinase JAK2/0.516
3eyhIZATyrosine-protein kinase JAK1/0.515
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.515
2b7aIZATyrosine-protein kinase JAK2/0.513
4hvh19RTyrosine-protein kinase JAK32.7.10.20.513
3nynSGVG protein-coupled receptor kinase 62.7.11.160.512
4jia1K3Tyrosine-protein kinase JAK2/0.511
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.510
5dr6SKEAurora kinase A2.7.11.10.509
2zoq5IDMitogen-activated protein kinase 32.7.11.240.508
3cgfJNFMitogen-activated protein kinase 102.7.11.240.508
3sheI85MAP kinase-activated protein kinase 32.7.11.10.508
4fkv61KCyclin-dependent kinase 22.7.11.220.507
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.507
5dr9SKEAurora kinase A2.7.11.10.507
5drdATPAurora kinase A2.7.11.10.507
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.506
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.506
1pxlCK4Cyclin-dependent kinase 22.7.11.220.505
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.505
4ek816KCyclin-dependent kinase 22.7.11.220.504
4hvi19STyrosine-protein kinase JAK32.7.10.20.504
3hmm855TGF-beta receptor type-12.7.11.300.503
4bgh3I6Cyclin-dependent kinase 22.7.11.220.503
4c62XWWTyrosine-protein kinase JAK2/0.502
1xjdSTUProtein kinase C theta type2.7.11.130.501
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.501
4c61LMMTyrosine-protein kinase JAK2/0.501
1oirHDYCyclin-dependent kinase 22.7.11.220.500
3mtfA3FActivin receptor type-12.7.11.300.500
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.500
4iva1J5Tyrosine-protein kinase JAK2/0.500
4ivc1J6Tyrosine-protein kinase JAK1/0.500
1ol5ADPAurora kinase A2.7.11.10.499
2uzbC75Cyclin-dependent kinase 22.7.11.220.499
4anmWULCasein kinase II subunit alpha2.7.11.10.499
1h1s4SPCyclin-dependent kinase 22.7.11.220.498
3lxkMI1Tyrosine-protein kinase JAK32.7.10.20.498
4bcoT6QCyclin-dependent kinase 22.7.11.220.498
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.498
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.497
4dymIYZActivin receptor type-12.7.11.300.495
4e93GUITyrosine-protein kinase Fes/Fps2.7.10.20.495
4jajXU1Aurora kinase A2.7.11.10.495
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.494
2w1hL0FCyclin-dependent kinase 22.7.11.220.493
2xa4AZ5Tyrosine-protein kinase JAK2/0.493
5cnnANPEpidermal growth factor receptor2.7.10.10.493
1bw9NADPhenylalanine dehydrogenase/0.492
2w9hTOPDihydrofolate reductase1.5.1.30.492
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.492
4erwSTUCyclin-dependent kinase 22.7.11.220.492
2b53D23Cyclin-dependent kinase 22.7.11.220.491
3ggfGVDSerine/threonine-protein kinase 26/0.491
4o0sADNAurora kinase A2.7.11.10.491
1aq1STUCyclin-dependent kinase 22.7.11.220.490
2h96893Mitogen-activated protein kinase 82.7.11.240.490
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.490
5dpvSKEAurora kinase A2.7.11.10.490
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.489
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.489
3sw418KCyclin-dependent kinase 22.7.11.220.489
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.488
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.488
2y9qANPMitogen-activated protein kinase 12.7.11.240.488
3gxlQIGTGF-beta receptor type-12.7.11.300.488
3lfnA27Cyclin-dependent kinase 22.7.11.220.488
4gub0Y4Casein kinase II subunit alpha2.7.11.10.488
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.488
2r3jSCJCyclin-dependent kinase 22.7.11.220.487
3at3ATKCasein kinase II subunit alpha2.7.11.10.487
4jqeANPCasein kinase II subunit alpha2.7.11.10.487
2vv9IM9Cyclin-dependent kinase 22.7.11.220.486
3i60E86Mitogen-activated protein kinase 12.7.11.240.486
3w33W19Epidermal growth factor receptor2.7.10.10.486
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.486
4o0wADNAurora kinase A2.7.11.10.486
1me6IVSPlasmepsin-23.4.23.390.485
1y91CT9Cyclin-dependent kinase 22.7.11.220.485
2uzoC62Cyclin-dependent kinase 22.7.11.220.485
2xmyCDKCyclin-dependent kinase 22.7.11.220.485
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.485
4hvg19QTyrosine-protein kinase JAK32.7.10.20.485
4ji91M3Tyrosine-protein kinase JAK2/0.485
4lfiGNPCasein kinase II subunit alpha2.7.11.10.485
2ycfYCFSerine/threonine-protein kinase Chk22.7.11.10.484
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.484
3r8lZ30Cyclin-dependent kinase 22.7.11.220.484
4e200MYNon-receptor tyrosine-protein kinase TYK22.7.10.20.484
4eor4SPCyclin-dependent kinase 22.7.11.220.484
1oitHDTCyclin-dependent kinase 22.7.11.220.483
3rmf20ZCyclin-dependent kinase 22.7.11.220.483
3s1h56ZCyclin-dependent kinase 22.7.11.220.483
4e4m0NHTyrosine-protein kinase JAK2/0.483
1ykr628Cyclin-dependent kinase 22.7.11.220.482
3bbrBHYGlutamate receptor 2/0.482
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.482
3k5uPFQAurora kinase A2.7.11.10.482
3zmmF9JTyrosine-protein kinase JAK2/0.482
4ehzJAKTyrosine-protein kinase JAK1/0.482
4ewhT77Activated CDC42 kinase 1/0.482
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.482
3kc3MK2MAP kinase-activated protein kinase 22.7.11.10.481
3nux3NVCyclin-dependent kinase 62.7.11.220.481
4o0uADNAurora kinase A2.7.11.10.481
4r20AERCytochrome P450 family 17 polypeptide 2/0.481
3oqkS52Renin3.4.23.150.480
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.480
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.480
1pxmCK5Cyclin-dependent kinase 22.7.11.220.479
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.479
2xngA0HAurora kinase A2.7.11.10.479
3lpbNVBTyrosine-protein kinase JAK2/0.479
3rk507ZCyclin-dependent kinase 22.7.11.220.479
4fko20KCyclin-dependent kinase 22.7.11.220.479
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.479
2a0cCK9Cyclin-dependent kinase 22.7.11.220.478
2b52D42Cyclin-dependent kinase 22.7.11.220.478
2np8CC3Aurora kinase A2.7.11.10.478
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.478
2ydkYDKSerine/threonine-protein kinase Chk12.7.11.10.478
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.478
3pqbVGPPutative oxidoreductase/0.478
3t1tGDPProbable gliding protein mglA/0.478
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.478
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.478
1m2qMNXCasein kinase II subunit alpha2.7.11.10.477
1pxpCK8Cyclin-dependent kinase 22.7.11.220.477
3lfqA28Cyclin-dependent kinase 22.7.11.220.477
3r83Z14Cyclin-dependent kinase 22.7.11.220.477
1dayGNPCasein kinase II subunit alpha2.7.11.10.476
1e9hINRCyclin-dependent kinase 22.7.11.220.476
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.476
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.476
3cukFADD-amino-acid oxidase1.4.3.30.476
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.476
2c6o4SPCyclin-dependent kinase 22.7.11.220.475
2i4zDRHPeroxisome proliferator-activated receptor gamma/0.475
3eljGS7Mitogen-activated protein kinase 82.7.11.240.475
3gubGUBDeath-associated protein kinase 12.7.11.10.475
3qqhX0ACyclin-dependent kinase 22.7.11.220.475
3rk708ZCyclin-dependent kinase 22.7.11.220.475
4dxd9PCCell division protein FtsZ/0.475
4f650S9Fibroblast growth factor receptor 1/0.475
5cnoANPEpidermal growth factor receptor2.7.10.10.475
1xddAAYIntegrin alpha-L/0.474
1xkkFMMEpidermal growth factor receptor2.7.10.10.474
2fumMIXSerine/threonine-protein kinase PknB2.7.11.10.474
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.474
2hckQUETyrosine-protein kinase HCK2.7.10.20.474
2pvmP29Casein kinase II subunit alpha2.7.11.10.474
2w1fL0FAurora kinase A2.7.11.10.474
4elb34RDihydrofolate reductase/0.474
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.474
1kkq471Peroxisome proliferator-activated receptor alpha/0.473
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.473
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.473
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.473
1gii1PUCyclin-dependent kinase 22.7.11.220.472
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.472
2pvjP44Casein kinase II subunit alpha2.7.11.10.472
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.472
3rni21ZCyclin-dependent kinase 22.7.11.220.472
4k110J9Proto-oncogene tyrosine-protein kinase Src2.7.10.20.472
4loqSB4Mitogen-activated protein kinase 14/0.472
1pkgADPMast/stem cell growth factor receptor Kit2.7.10.10.471
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.471
2wotZZGTGF-beta receptor type-12.7.11.300.471
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.471
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.471
3pxkPXKFocal adhesion kinase 12.7.10.20.471
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.471
4enhFVXCholesterol 24-hydroxylase/0.471
4fod0UVALK tyrosine kinase receptor2.7.10.10.471
4fv5EK9Mitogen-activated protein kinase 12.7.11.240.471
2bheBRYCyclin-dependent kinase 22.7.11.220.470
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.470
2d29FADAcyl-CoA dehydrogenase/0.470
2om9AJAPeroxisome proliferator-activated receptor gamma/0.470
2wtiWTISerine/threonine-protein kinase Chk22.7.11.10.470
2xnbY8LCyclin-dependent kinase 22.7.11.220.470
3eb0DRKUncharacterized protein/0.470
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.470
1bwsNDPGDP-L-fucose synthase/0.469
1bygSTUTyrosine-protein kinase CSK/0.469
1u4dDBQActivated CDC42 kinase 1/0.469
2r3iSCFCyclin-dependent kinase 22.7.11.220.469
2r64740Cyclin-dependent kinase 22.7.11.220.469
3a62STURibosomal protein S6 kinase beta-12.7.11.10.469
3et7349Protein-tyrosine kinase 2-beta2.7.10.20.469
3qtuX44Cyclin-dependent kinase 22.7.11.220.469
3tvuB37Acetyl-CoA carboxylase/0.469
3zuxTCHTransporter/0.469
4ele31IDihydrofolate reductase/0.469
4eon1ROCyclin-dependent kinase 22.7.11.220.469
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.469
4fks46KCyclin-dependent kinase 22.7.11.220.469
4i22IREEpidermal growth factor receptor2.7.10.10.469
4ivd15TTyrosine-protein kinase JAK1/0.469
5e8wSTUTGF-beta receptor type-12.7.11.300.469
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.468
4cdmFADDeoxyribodipyrimidine photolyase/0.468
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.468
4fklCK2Cyclin-dependent kinase 22.7.11.220.468
4h3qANPMitogen-activated protein kinase 12.7.11.240.468
4nifANPMitogen-activated protein kinase 12.7.11.240.468
5dnrATPAurora kinase A2.7.11.10.468
5e92ANPTGF-beta receptor type-22.7.11.300.468
1e1xNW1Cyclin-dependent kinase 22.7.11.220.467
1h0w207Cyclin-dependent kinase 22.7.11.220.467
1ny3ADPMAP kinase-activated protein kinase 22.7.11.10.467
1py5PY1TGF-beta receptor type-12.7.11.300.467
2f4bEHAPeroxisome proliferator-activated receptor gamma/0.467
2uzeC95Cyclin-dependent kinase 22.7.11.220.467
3l8p0CEAngiopoietin-1 receptor2.7.10.10.467
3ut5LOCTubulin beta chain/0.467
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.467
4acm7YGCyclin-dependent kinase 22.7.11.220.467
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.467
4fv6E57Mitogen-activated protein kinase 12.7.11.240.467
4xgxADPFAD:protein FMN transferase/0.467
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.466
2uznC96Cyclin-dependent kinase 22.7.11.220.466
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.466
4dgmAGICasein kinase II subunit alpha2.7.11.10.466
4fyo0VFTyrosine-protein kinase SYK2.7.10.20.466
4gj30XPNon-receptor tyrosine-protein kinase TYK22.7.10.20.466
5dt3ATPAurora kinase A2.7.11.10.466
5e8ySTUTGF-beta receptor type-22.7.11.300.466
1unlRRCCyclin-dependent-like kinase 52.7.11.10.465
1urwI1PCyclin-dependent kinase 22.7.11.220.465
2q5g1FAPeroxisome proliferator-activated receptor delta/0.465
3b70NAPEnoyl reductase LovC10.465
3flkNAITartrate dehydrogenase/decarboxylase1.1.1.930.465
3r73X87Cyclin-dependent kinase 22.7.11.220.465
4ejn0R4RAC-alpha serine/threonine-protein kinase2.7.11.10.465
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.465
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.465
4riyANPReceptor tyrosine-protein kinase erbB-32.7.10.10.465
4z5wILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.465
1dhrNADDihydropteridine reductase1.5.1.340.464
1ia3TQ5Dihydrofolate reductase1.5.1.30.464
1lf3EH5Plasmepsin-23.4.23.390.464
1pxoCK7Cyclin-dependent kinase 22.7.11.220.464
2csnCKICasein kinase I homolog 12.7.11.10.464
2vu3LZECyclin-dependent kinase 22.7.11.220.464
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.464
2xneASHAurora kinase A2.7.11.10.464
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.464
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.464
3lxpIZANon-receptor tyrosine-protein kinase TYK22.7.10.20.464
3qcs3Q13-phosphoinositide-dependent protein kinase 12.7.11.10.464
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.464
4ei40Q2Tyrosine-protein kinase JAK1/0.464
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.464
4k771Q4Tyrosine-protein kinase JAK1/0.464
2dv3SAHDiphthine synthase/0.463
2r3lSCWCyclin-dependent kinase 22.7.11.220.463
2vtoLZ8Cyclin-dependent kinase 22.7.11.220.463
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.463
3kvxFMYMitogen-activated protein kinase 102.7.11.240.463
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.463
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.463
4m69ANPReceptor-interacting serine/threonine-protein kinase 32.7.11.10.463
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.462
1jipKTN6-deoxyerythronolide B hydroxylase/0.462
1zeoC01Peroxisome proliferator-activated receptor gamma/0.462
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.462
2iw94SPCyclin-dependent kinase 22.7.11.220.462
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.462
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
3own3OWRenin3.4.23.150.462
3r7vZ02Cyclin-dependent kinase 22.7.11.220.462
3rak03ZCyclin-dependent kinase 22.7.11.220.462
4c02TAKActivin receptor type-12.7.11.300.462
4deeADPAurora kinase A2.7.11.10.462
4n9iPCGCatabolite expression activator/0.462
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.462
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.462
4y95746Tyrosine-protein kinase/0.462
1gij2PUCyclin-dependent kinase 22.7.11.220.461
1lp4ANPCasein kinase II subunit alpha2.7.11.10.461
1mq4ADPAurora kinase A2.7.11.10.461
1rdt570Peroxisome proliferator-activated receptor gamma/0.461
1zz2B11Mitogen-activated protein kinase 14/0.461
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.461
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.461
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.461
3qtrX36Cyclin-dependent kinase 22.7.11.220.461
3tk3CPZCytochrome P450 2B41.14.14.10.461
3vob9PCCell division protein FtsZ/0.461
3w551FMMitogen-activated protein kinase 12.7.11.240.461
4a81DXCMajor pollen allergen Bet v 1-A/0.461
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.461
4gj20XHNon-receptor tyrosine-protein kinase TYK22.7.10.20.461
4im2BX7Serine/threonine-protein kinase TBK12.7.11.10.461
1lf2R37Plasmepsin-23.4.23.390.460
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.460
2a4lRRCCyclin-dependent kinase 22.7.11.220.460
2cchATPCyclin-dependent kinase 22.7.11.220.460
2duv371Cyclin-dependent kinase 22.7.11.220.460
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.460
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.460
3dd125DGlycogen phosphorylase, liver form2.4.1.10.460
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.460
3kgaLX9MAP kinase-activated protein kinase 22.7.11.10.460
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.460
3zh8C58Protein kinase C iota type2.7.11.130.460
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.460
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.460
4pl4ADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.460
4uyf73BBromodomain-containing protein 2/0.460
1k7l544Peroxisome proliferator-activated receptor alpha/0.459
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.459
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.459
2c5yMTWCyclin-dependent kinase 22.7.11.220.459
2gjlFMNNitronate monooxygenase1.13.12.160.459
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.459
2j0m4STFocal adhesion kinase 12.7.10.20.459
3nlb5BESerine/threonine-protein kinase Chk12.7.11.10.459
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.459
4i02CMPcAMP-activated global transcriptional regulator CRP/0.459
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.459
4zjuNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.459
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.459
1bdlIM1Gag-Pol polyprotein3.4.23.160.458
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
2b55D31Cyclin-dependent kinase 22.7.11.220.458
2bb9AKCGag-Pol polyprotein3.4.23.160.458
2ccu2D9Heat shock protein HSP 90-alpha/0.458
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
2fxeDR7Gag-Pol polyprotein3.4.23.160.458
2w06FRVCyclin-dependent kinase 22.7.11.220.458
2w17I19Cyclin-dependent kinase 22.7.11.220.458
3bxsDRSGag-Pol polyprotein3.4.23.160.458
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.458
3pmy41LEndothiapepsin3.4.23.220.458
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.458
4f9c0SXCell division cycle 7-related protein kinase2.7.11.10.458
4jr7GNPCasein kinase II subunit alpha2.7.11.10.458
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.458
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.458
1ad5ANPTyrosine-protein kinase HCK2.7.10.20.457
1fm6BRLPeroxisome proliferator-activated receptor gamma/0.457
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.457
1qiqACCIsopenicillin N synthase1.21.3.10.457
1sh9RITGag-Pol polyprotein3.4.23.160.457
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
2x7hPFNProstaglandin reductase 310.457
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.457
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.457
3nieANPMitogen-activated protein kinase/0.457
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.457
3qtzX42Cyclin-dependent kinase 22.7.11.220.457
3r7yZ04Cyclin-dependent kinase 22.7.11.220.457
3rkb12ZCyclin-dependent kinase 22.7.11.220.457
3v9y24LPeroxisome proliferator-activated receptor gamma/0.457
3w10RO9Aurora kinase A2.7.11.10.457
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.457
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.457
4e5w0NTTyrosine-protein kinase JAK1/0.457
4fv2EK5Mitogen-activated protein kinase 12.7.11.240.457
4fv4EK7Mitogen-activated protein kinase 12.7.11.240.457
4fv7E94Mitogen-activated protein kinase 12.7.11.240.457
4gii0X6Non-receptor tyrosine-protein kinase TYK22.7.10.20.457
4q72FADBifunctional protein PutA/0.457
1dawANPCasein kinase II subunit alpha2.7.11.10.456
1eioGCHGastrotropin/0.456
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.456
1y0s331Peroxisome proliferator-activated receptor delta/0.456
1yw2PGJMitogen-activated protein kinase 14/0.456
2cig1DGDihydrofolate reductase1.5.1.30.456
2yr5FADPhenylalanine 2-monooxygenase precursor1.13.12.90.456
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.456
3iaeD7KBenzaldehyde lyase/0.456
3oqfS51Renin3.4.23.150.456
3pe2E1BCasein kinase II subunit alpha2.7.11.10.456
4b0gVEKAurora kinase A2.7.11.10.456
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.456
4fmqANPMitogen-activated protein kinase 12.7.11.240.456
4iah1DXAlr2278 protein/0.456
4jq7KJQEpidermal growth factor receptor2.7.10.10.456
4k6z1Q3Tyrosine-protein kinase JAK1/0.456
1fm4DXCMajor pollen allergen Bet v 1-L/0.455
1hbvGANGag-Pol polyprotein/0.455
2e15SAHDiphthine synthase/0.455
2nq8ZIDEnoyl-ACP reductase/0.455
2ou2ACOHistone acetyltransferase KAT5/0.455
2v7a627Tyrosine-protein kinase ABL12.7.10.20.455
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.455
3ezvEZVCyclin-dependent kinase 22.7.11.220.455
3nwxKVSGag-Pol polyprotein3.4.23.160.455
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4c0bATPmRNA cleavage and polyadenylation factor CLP1/0.455
4c3rACPAurora kinase A2.7.11.10.455
4ia3BIVVitamin D3 receptor A/0.455
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.455
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.455
4q73FADBifunctional protein PutA/0.455
4rqkATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3sn6P0GBeta-2 adrenergic receptor/0.455
1h1r6CPCyclin-dependent kinase 22.7.11.220.454
1nyxDRFPeroxisome proliferator-activated receptor gamma/0.454
1phhFADp-hydroxybenzoate hydroxylase/0.454
1pyePM1Cyclin-dependent kinase 22.7.11.220.454
1rw8580TGF-beta receptor type-12.7.11.300.454
1wvxBD4Death-associated protein kinase 12.7.11.10.454
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.454
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.454
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.454
2itqITQEpidermal growth factor receptor2.7.10.10.454
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.454
2xb7GUIALK tyrosine kinase receptor2.7.10.10.454
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.454
2zbaZBATrichothecene 3-O-acetyltransferase/0.454
3a9wNADNDP-sugar epimerase/0.454
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.454
3prfFP3Serine/threonine-protein kinase B-raf2.7.11.10.454
3qqgX06Cyclin-dependent kinase 22.7.11.220.454
3slkNDPPolyketide synthase extender module 2/0.454
3uyt0CKCasein kinase I isoform delta2.7.11.10.454
3w32W32Epidermal growth factor receptor2.7.10.10.454
3zm422TDual specificity mitogen-activated protein kinase kinase 12.7.12.20.454
4a84DXCMajor pollen allergen Bet v 1-A/0.454
4bn1ADPAurora kinase A2.7.11.10.454
4ckjADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.454
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.454
4hgs15GCasein kinase I isoform gamma-32.7.11.10.454
4iwd1JCHepatocyte growth factor receptor2.7.10.10.454
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.454
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
4rrrA3TThreonine--tRNA ligase6.1.1.30.454
4tuvCPZCytochrome P450 1191.140.454
5k2aZMAAdenosine receptor A2a/0.454
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.453
1nooCAHCamphor 5-monooxygenase1.14.15.10.453
1pg3PRXAcetyl-coenzyme A synthetase/0.453
1u54ACPActivated CDC42 kinase 1/0.453
2exmZIPCyclin-dependent kinase 22.7.11.220.453
2h9iEADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.453
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2w1gL0GAurora kinase A2.7.11.10.453
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.453
3l6jZ90Alr2278 protein/0.453
3r8vZ62Cyclin-dependent kinase 22.7.11.220.453
3v5l0G1Tyrosine-protein kinase ITK/TSK2.7.10.20.453
3zdu38RCyclin-dependent kinase-like 32.7.11.220.453
4a312CBGlycylpeptide N-tetradecanoyltransferase/0.453
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.453
4kbk1QGCasein kinase I isoform delta2.7.11.10.453
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.453
4qnyANPMitogen activated protein kinase, putative/0.453
5eypLOCTubulin beta chain/0.453
1b38ATPCyclin-dependent kinase 22.7.11.220.452
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
1f0xFADD-lactate dehydrogenase1.1.1.280.452
1hviA77Protease/0.452
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.452
1oecAA2Fibroblast growth factor receptor 2/0.452
1zdwFLVPrenyltransferase/0.452
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
2ds11CDCyclin-dependent kinase 22.7.11.220.452
2dsgSAHDiphthine synthase/0.452
2pmnK51Protein kinase 7/0.452
3ddqRRCCyclin-dependent kinase 22.7.11.220.452
3fz1B98Cyclin-dependent kinase 22.7.11.220.452
3mdmFJZCholesterol 24-hydroxylase/0.452
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.452
3vt9YI4Vitamin D3 receptor/0.452
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.452
3zls92PDual specificity mitogen-activated protein kinase kinase 12.7.12.20.452
4deaNHIAurora kinase A2.7.11.10.452
4dt9GMPAPH(2'')-Id/0.452
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.452
5dosATPAurora kinase A2.7.11.10.452
1h1q2A6Cyclin-dependent kinase 22.7.11.220.451
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.451
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.451
1rkxNADCDP-D-glucose-4,6-dehydratase/0.451
1v1k3FPCyclin-dependent kinase 22.7.11.220.451
1w6hTITPlasmepsin-23.4.23.390.451
1w8cN69Cyclin-dependent kinase 22.7.11.220.451
1zemNADXylitol dehydrogenase/0.451
2ejzSAHDiphthine synthase/0.451
2vn0TDZCytochrome P450 2C8/0.451
2w05FRTCyclin-dependent kinase 22.7.11.220.451
2xru400Aurora kinase A2.7.11.10.451
3hx4ANPCalmodulin-domain protein kinase 1/0.451
3iggEFQCyclin-dependent kinase 22.7.11.220.451
3lq5SLQCyclin-dependent kinase 92.7.11.220.451
3mdvCL6Cholesterol 24-hydroxylase/0.451
3r9oZ71Cyclin-dependent kinase 22.7.11.220.451
3t2yFADSulfide-quinone reductase/0.451
4bc7FADAlkyldihydroxyacetonephosphate synthase, peroxisomal2.5.1.260.451
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.451
4bgg844Activin receptor type-12.7.11.300.451
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.451
4kd11QKCyclin-dependent kinase 22.7.11.220.451
4qmtH1NSerine/threonine-protein kinase 242.7.11.10.451
1b4vFADCholesterol oxidase1.1.3.60.450
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.450
1oi9N20Cyclin-dependent kinase 22.7.11.220.450
1t2cNAIL-lactate dehydrogenase1.1.1.270.450
1vikBAYGag-Pol polyprotein/0.450
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.450
2gqpPA7Endoplasmin/0.450
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.450
2wedPP6Penicillopepsin-13.4.23.200.450
3bc3OPTCathepsin L13.4.22.150.450
3cyxROCGag-Pol polyprotein3.4.23.160.450
3efwAK8Aurora kinase A2.7.11.10.450
3pxyJWSCyclin-dependent kinase 22.7.11.220.450
3qzhX69Cyclin-dependent kinase 22.7.11.220.450
3vt8YI3Vitamin D3 receptor/0.450
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4b7xNAPProbable oxidoreductase/0.450
4c58824Cyclin-G-associated kinase2.7.11.10.450
4dtaADNAPH(2'')-Id/0.450
4e4l0NHTyrosine-protein kinase JAK1/0.450
4ejmNAPPutative zinc-binding dehydrogenase/0.450
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.450
4fk60UJTyrosine-protein kinase JAK1/0.450
4ix6ADPUncharacterized protein/0.450
4lyn1YGCyclin-dependent kinase 22.7.11.220.450
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.450
5iu86DZAdenosine receptor A2a/0.450
1bmfANPATP synthase subunit alpha, mitochondrial/0.449
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.449
1c1dNAIPhenylalanine dehydrogenase/0.449
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1mjbACOHistone acetyltransferase ESA1/0.449
1mokFAD2-oxopropyl-CoM reductase, carboxylating1.8.1.50.449
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.449
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.449
1ydtIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.449
2ozoANPTyrosine-protein kinase ZAP-702.7.10.20.449
2p5fSAHDiphthine synthase/0.449
2vwqNAPGlucose 1-dehydrogenase/0.449
3lsiFADPyranose 2-oxidase/0.449
3nxe2NCProtease/0.449
3orkAGSSerine/threonine protein kinase/0.449
3oroAGSSerine/threonine protein kinase/0.449
3qlrNDPDihydrofolate reductase1.5.1.30.449
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.449
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.449
4fl2ANPTyrosine-protein kinase SYK2.7.10.20.449
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.449
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.449
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.449
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
4uymVOR14-alpha sterol demethylase Cyp51B/0.449
1dhjMTXDihydrofolate reductase1.5.1.30.448
1ha3MAUElongation factor Tu-A/0.448
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.448
1ma0NADAlcohol dehydrogenase class-31.1.1.10.448
1p2a5BNCyclin-dependent kinase 22.7.11.220.448
1pxjCK2Cyclin-dependent kinase 22.7.11.220.448
1xl2189Gag-Pol polyprotein3.4.23.160.448
2nliFMNLactate oxidase/0.448
2uzdC85Cyclin-dependent kinase 22.7.11.220.448
2znnS44Peroxisome proliferator-activated receptor alpha/0.448
3b6zCO7Enoyl reductase LovC10.448
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.448
3pj8404Cyclin-dependent kinase 22.7.11.220.448
3qu0X40Cyclin-dependent kinase 22.7.11.220.448
3vvpBNUUncharacterized protein/0.448
4dgo0JWCasein kinase II subunit alpha2.7.11.10.448
4elg52JDihydrofolate reductase/0.448
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.448
4jik1KOSerine/threonine-protein kinase Chk12.7.11.10.448
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.448
1bxoPP7Penicillopepsin-13.4.23.200.447
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1i5zCMPcAMP-activated global transcriptional regulator CRP/0.447
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.447
2g226IGRenin3.4.23.150.447
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.447
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.447
2jdvL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2pobGW4Peroxisome proliferator-activated receptor gamma/0.447
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.447
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.447
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.447
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.447
3gu83GUDeath-associated protein kinase 12.7.11.10.447
3in6FMNUncharacterized protein/0.447
3orfNADDihydropteridine reductase1.5.1.340.447
3rqhB6PADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.447
3s3r0IWCathepsin B-like peptidase (C01 family)/0.447
3t113T1Gag-Pol polyprotein3.4.23.160.447
3vf80JETyrosine-protein kinase SYK2.7.10.20.447
3zewSTUEphrin type-B receptor 42.7.10.10.447
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.447
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.447
4g3jVNTLanosterol 14-alpha-demethylase/0.447
4hj6FMNLOV protein/0.447
4j5j478Gag-Pol polyprotein3.4.23.160.447
4q71FADBifunctional protein PutA/0.447
1dr2TAPDihydrofolate reductase1.5.1.30.446
1hk1T44Serum albumin/0.446
1iziQ50Gag-Pol polyprotein3.4.23.160.446
1sguMK1Gag-Pol polyprotein3.4.23.160.446
2c6iDT1Cyclin-dependent kinase 22.7.11.220.446
2el0SAHDiphthine synthase/0.446
2f3kRO1Protease/0.446
2g76NADD-3-phosphoglycerate dehydrogenase1.1.1.950.446
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.446
2jkkBI9Focal adhesion kinase 12.7.10.20.446
2wpxACOOrf14/0.446
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.446
2x1nX1NCyclin-dependent kinase 22.7.11.220.446
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.446
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.446
2znpK55Peroxisome proliferator-activated receptor delta/0.446
3ddpRC8Cyclin-dependent kinase 22.7.11.220.446
3em4DR7Gag-Pol polyprotein3.4.23.160.446
3emg685Tyrosine-protein kinase SYK2.7.10.20.446
3ocpCMPcGMP-dependent protein kinase 12.7.11.120.446
3r1yX76Cyclin-dependent kinase 22.7.11.220.446
3raiX85Cyclin-dependent kinase 22.7.11.220.446
3t3c017Gag-Pol polyprotein3.4.23.160.446
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.446
3vryB43Tyrosine-protein kinase HCK2.7.10.20.446
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.446
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.446
4do30LAFatty-acid amide hydrolase 13.5.1.990.446
4e5yNDPGDP-L-fucose synthase1.1.1.2710.446
4fv9E71Mitogen-activated protein kinase 12.7.11.240.446
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.446
4k33ACPFibroblast growth factor receptor 32.7.10.10.446
4kb81QOCasein kinase I isoform delta2.7.11.10.446
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.446
4l7sG7KTyrosine-protein kinase ITK/TSK2.7.10.20.446
4mokFADPyranose 2-oxidase/0.446
4rqvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
5cshATPCasein kinase II subunit alpha2.7.11.10.446
5eccNAPDehydrofolate reductase type I/0.446
1nvmNADAcetaldehyde dehydrogenase1.2.1.100.445
1z5mLI83-phosphoinositide-dependent protein kinase 12.7.11.10.445
2a94AP0L-lactate dehydrogenase1.1.1.270.445
2aqkNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.445
2gjnFMNNitronate monooxygenase1.13.12.160.445
2ovhAS0Progesterone receptor/0.445
2p2bPRXAcetyl-coenzyme A synthetase/0.445
2po7CHDFerrochelatase, mitochondrial4.99.1.10.445
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.445
3qtwX3ACyclin-dependent kinase 22.7.11.220.445
3r6xX84Cyclin-dependent kinase 22.7.11.220.445
3sf6FDAGlutaryl-CoA dehydrogenase/0.445
4eok4SPCyclin-dependent kinase 22.7.11.220.445
4fob0USALK tyrosine kinase receptor2.7.10.10.445
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.445
4hjoAQ4Epidermal growth factor receptor2.7.10.10.445
4i5cC5ITyrosine-protein kinase JAK1/0.445
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
5k2cZMAAdenosine receptor A2a/0.445
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.444
1k6tXN1Gag-Pol polyprotein3.4.23.160.444
1p4fDRGDeath-associated protein kinase 12.7.11.10.444
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
2c6lDT4Cyclin-dependent kinase 22.7.11.220.444
2iebZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2iw84SPCyclin-dependent kinase 22.7.11.220.444
2izt23DCasein kinase I isoform gamma-32.7.11.10.444
2jamJ60Calcium/calmodulin-dependent protein kinase type 1G2.7.11.170.444
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.444
2vtqLZACyclin-dependent kinase 22.7.11.220.444
2wihP48Cyclin-dependent kinase 22.7.11.220.444
2xs0ANPMitogen-activated protein kinase 82.7.11.240.444
2z6rSAHDiphthine synthase/0.444
3linE13Protease/0.444
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.444
3o96IQORAC-alpha serine/threonine-protein kinase2.7.11.10.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.444
3syiFADSulfide-quinone reductase/0.444
3vn2TLSPeroxisome proliferator-activated receptor gamma/0.444
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
4eevL1XHepatocyte growth factor receptor2.7.10.10.444
4elh53IDihydrofolate reductase/0.444
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
4xumIMNPeroxisome proliferator-activated receptor gamma/0.444
5k2bZMAAdenosine receptor A2a/0.444
1k6cMK1Gag-Pol polyprotein3.4.23.160.443
1oiyN41Cyclin-dependent kinase 22.7.11.220.443
1rx1NAPDihydrofolate reductase1.5.1.30.443
1u4oNDDL-lactate dehydrogenase1.1.1.270.443
2bkzSBCCyclin-dependent kinase 22.7.11.220.443
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.443
2c6tDT5Cyclin-dependent kinase 22.7.11.220.443
2g247IGRenin3.4.23.150.443
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.443
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.443
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.443
2r3o2SCCyclin-dependent kinase 22.7.11.220.443
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.443
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.443
2znq401Peroxisome proliferator-activated receptor delta/0.443
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.443
3dcrKVSProtease/0.443
3gw9VNILanosterol 14-alpha-demethylase/0.443
3k4nFADPyranose 2-oxidase/0.443
3nwq2NCGag-Pol polyprotein3.4.23.160.443
3vqsJT1Genome polyprotein/0.443
4bbfO19Tyrosine-protein kinase JAK2/0.443
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.443
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.443
4foc0UUALK tyrosine kinase receptor2.7.10.10.443
4ijp1EHSerine/threonine-protein kinase PRP4 homolog2.7.11.10.443
4nmdFDABifunctional protein PutA/0.443
4o4fATPKinase/0.443
1di8DTQCyclin-dependent kinase 22.7.11.220.442
1fmlRTLRetinol dehydratase/0.442
1gih1PUCyclin-dependent kinase 22.7.11.220.442
1hckATPCyclin-dependent kinase 22.7.11.220.442
1hvsA77Gag-Pol polyprotein/0.442
1i5rHYCEstradiol 17-beta-dehydrogenase 11.1.1.620.442
1idb0DOGag-Pol polyprotein/0.442
1k74544Peroxisome proliferator-activated receptor gamma/0.442
1oguST8Cyclin-dependent kinase 22.7.11.220.442
1pmn984Mitogen-activated protein kinase 102.7.11.240.442
1r6g442Thyroid hormone receptor beta/0.442
2dwbANPAurora kinase A2.7.11.10.442
2oxtSAMGenome polyprotein/0.442
2qi6MZ8Gag-Pol polyprotein/0.442
2yaaATPDeath-associated protein kinase 2/0.442
3oom507Activin receptor type-12.7.11.300.442
3ortAGSSerine/threonine protein kinase/0.442
3pvwQRXBeta-adrenergic receptor kinase 12.7.11.150.442
3r7eX88Cyclin-dependent kinase 22.7.11.220.442
4e730NRMitogen-activated protein kinase 82.7.11.240.442
4ivb1J5Tyrosine-protein kinase JAK1/0.442
4jbqVX6Aurora kinase A2.7.11.10.442
4jq8KJ8Epidermal growth factor receptor2.7.10.10.442
4l435FIRibosomal protein S6 kinase beta-12.7.11.10.442
4lopSB4Mitogen-activated protein kinase 14/0.442
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.442
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.442
1blzACVIsopenicillin N synthase1.21.3.10.441
1e3eNAIAlcohol dehydrogenase 41.1.1.10.441
1g1aNADdTDP-glucose 4,6-dehydratase/0.441
1tj2FADBifunctional protein PutA1.5.5.20.441
1xe55FEPlasmepsin-23.4.23.390.441
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.441
2b9iADPMitogen-activated protein kinase FUS32.7.11.240.441
2e9dB76Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.441
2eiiNAD1-pyrroline-5-carboxylate dehydrogenase/0.441
2fznFADBifunctional protein PutA1.5.5.20.441
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.441
2p4iMR9Angiopoietin-1 receptor2.7.10.10.441
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.441
2qi3MZ5Gag-Pol polyprotein/0.441
2uxoTACHTH-type transcriptional regulator TtgR/0.441
2vw5BC6ATP-dependent molecular chaperone HSP82/0.441
2wmvZYVSerine/threonine-protein kinase Chk12.7.11.10.441
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.441
2z3lPHE_ARG_TYR_LEU_GLYLeucyl/phenylalanyl-tRNA--protein transferase2.3.2.60.441
3a1nNADNDP-sugar epimerase/0.441
3c15FOKAdenylate cyclase type 2/0.441
3c15FOKAdenylate cyclase type 5/0.441
3frqERYErythromycin resistance repressor protein/0.441
3h06VBPGlutamate receptor 2/0.441
3ibdCPZCytochrome P450 2B61.14.130.441
3k6l2BBPeptide deformylase3.5.1.880.441
3wecAUICytochrome P450/0.441
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.441
4ambDUDPutative glycosyl transferase/0.441
4awiAQ2Mitogen-activated protein kinase 82.7.11.240.441
4b8wNAPGDP-L-fucose synthase1.1.1.2710.441
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.441
4dx9SER_ALA_VAL_THRIntegrin beta-1/0.441
4dx9SER_ALA_VAL_THRIntegrin beta-1-binding protein 1/0.441
4fx360KCyclin-dependent kinase 22.7.11.220.441
4jin1L7RIO-type serine/threonine-protein kinase Rio12.7.11.10.441
4l425FIRibosomal protein S6 kinase beta-12.7.11.10.441
4mwhATPCasein kinase II subunit alpha2.7.11.10.441
4n6hEJ4Delta-type opioid receptor/0.441
5av2KMPDeath-associated protein kinase 12.7.11.10.441
5cccDDFDihydrofolate reductase1.5.1.30.441
1bil0IURenin3.4.23.150.440
1difA85Gag-Pol polyprotein/0.440
1me7MOAInosine-5'-monophosphate dehydrogenase/0.440
2eh2SAHDiphthine synthase/0.440
2fxdDR7Pol polyprotein/0.440
2hfpNSIPeroxisome proliferator-activated receptor gamma/0.440
2ijmATPFocal adhesion kinase 12.7.10.20.440
2is0I03Beta-secretase 13.4.23.460.440
2itpAEEEpidermal growth factor receptor2.7.10.10.440
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.440
2vtrLZBCyclin-dependent kinase 22.7.11.220.440
2xlsFADPutative flavin-containing monooxygenase/0.440
2zdt46CMitogen-activated protein kinase 102.7.11.240.440
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.440
3ixp834Ecdysone receptor/0.440
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.440
3qx2X63Cyclin-dependent kinase 22.7.11.220.440
3wmxNADNAD dependent epimerase/dehydratase/0.440
3wv9FEGHmd co-occurring protein HcgE/0.440
4caxMYAGlycylpeptide N-tetradecanoyltransferase2.3.1.970.440
4fg8ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.440
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.440
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.440
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.440
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.440
4nk92K5Fibroblast growth factor receptor 1/0.440
4r21STRCytochrome P450 family 17 polypeptide 2/0.440
4r3aRBFBlue-light-activated histidine kinase 22.7.13.30.440
4xldBRLPeroxisome proliferator-activated receptor gamma/0.440
5jlaNADPutative short-chain dehydrogenase/reductase/0.440