sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2io8 | ADP | Bifunctional glutathionylspermidine synthetase/amidase |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 2io8 | ADP | Bifunctional glutathionylspermidine synthetase/amidase | / | 1.000 | |
| 2io7 | ANP | Bifunctional glutathionylspermidine synthetase/amidase | / | 0.571 | |
| 2ioa | ADP | Bifunctional glutathionylspermidine synthetase/amidase | / | 0.529 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.526 | |
| 1l8q | ADP | Chromosomal replication initiator protein DnaA | / | 0.525 | |
| 2a19 | ANP | Interferon-induced, double-stranded RNA-activated protein kinase | 2.7.11.1 | 0.511 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.504 | |
| 1qm5 | PLP | Maltodextrin phosphorylase | 2.4.1.1 | 0.496 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.495 | |
| 2o12 | FMN | Chorismate synthase | / | 0.493 | |
| 4d7m | TDC | Tetracycline repressor protein class D | / | 0.493 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.491 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.489 | |
| 4i8x | 6P3 | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.489 | |
| 4n57 | ADP | APH(2'')-Id | / | 0.489 | |
| 2pui | ADP | Methylthioribose kinase | 2.7.1.100 | 0.488 | |
| 2y3p | SM8 | DNA gyrase subunit A | / | 0.488 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.488 | |
| 3pjc | PJC | Tyrosine-protein kinase JAK3 | 2.7.10.2 | 0.488 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.488 | |
| 1i24 | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.487 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.486 | |
| 5iqb | GNP | Bifunctional AAC/APH | 2.3.1 | 0.486 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.485 | |
| 3a78 | 3EV | Vitamin D3 receptor | / | 0.485 | |
| 4bqy | FNT | Egl nine homolog 1 | / | 0.485 | |
| 4emy | PLP | Aminotransferase class I and II | / | 0.485 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.484 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.483 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.483 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.482 | |
| 2ofv | 242 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.482 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.481 | |
| 5c88 | COA | N-alpha-acetyltransferase | / | 0.481 | |
| 1kmv | LII | Dihydrofolate reductase | 1.5.1.3 | 0.480 | |
| 1s4d | SAH | Uroporphyrinogen-III C-methyltransferase | 2.1.1.107 | 0.480 | |
| 2p9c | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.480 | |
| 3hko | ANP | Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands | / | 0.480 | |
| 5iot | UMP | Flavin-dependent thymidylate synthase | 2.1.1.148 | 0.480 | |
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 0.479 | |
| 3tdw | GDP | Gentamicin resistance protein | / | 0.479 | |
| 4avl | TMP | Polymerase acidic protein | / | 0.479 | |
| 4k8a | K8A | Focal adhesion kinase 1 | 2.7.10.2 | 0.479 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.478 | |
| 4bqh | 9VU | UDP-N-acetylglucosamine pyrophosphorylase, putative | / | 0.477 | |
| 3dat | MTX | Dihydrofolate reductase | / | 0.476 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.476 | |
| 3d5w | ADP | Serine/threonine-protein kinase PLK | / | 0.475 | |
| 4qx5 | CMP | cGMP-dependent protein kinase 1 | 2.7.11.12 | 0.475 | |
| 4ruj | VDX | Vitamin D3 receptor A | / | 0.475 | |
| 4s33 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.475 | |
| 5fdg | 0N8 | Polymerase acidic protein | / | 0.475 | |
| 1ykd | CMP | Adenylate cyclase | / | 0.474 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.474 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.474 | |
| 2vnj | FAD | NADPH:ferredoxin reductase | / | 0.474 | |
| 4d9e | LCS | D-cysteine desulfhydrase | / | 0.474 | |
| 4ku3 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.474 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.474 | |
| 1i2c | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.473 | |
| 2e20 | B4P | Propionate kinase | / | 0.473 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.473 | |
| 4djx | 0KQ | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 5dt3 | ATP | Aurora kinase A | 2.7.11.1 | 0.473 | |
| 5iqh | GNP | Bifunctional AAC/APH | 2.3.1 | 0.473 | |
| 1bdl | IM1 | Gag-Pol polyprotein | 3.4.23.16 | 0.472 | |
| 1equ | EQI | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.472 | |
| 2o4j | VD4 | Vitamin D3 receptor | / | 0.472 | |
| 4uxx | ACP | Diacylglycerol kinase | 2.7.1.107 | 0.472 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.472 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.471 | |
| 2wd8 | VGF | Pteridine reductase | / | 0.471 | |
| 3v2b | AR6 | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.471 | |
| 1yqj | 6NP | Mitogen-activated protein kinase 14 | / | 0.470 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.470 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.470 | |
| 3hzi | ATP | Serine/threonine-protein kinase toxin HipA | / | 0.470 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.469 | |
| 1u3s | 797 | Estrogen receptor beta | / | 0.469 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.469 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.469 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.468 | |
| 2wzm | NA7 | Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346 | / | 0.468 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.468 | |
| 3cd5 | 7HI | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.468 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.468 | |
| 3vru | YS3 | Vitamin D3 receptor | / | 0.468 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.468 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.468 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.468 | |
| 1w7h | 3IP | Mitogen-activated protein kinase 14 | / | 0.467 | |
| 2wip | P49 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.467 | |
| 3ad6 | KSC | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.467 | |
| 3cvu | FAD | RE11660p | / | 0.467 | |
| 3n6n | BUP | Genome polyprotein | / | 0.467 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.467 | |
| 3qf9 | NM8 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.467 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.467 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.467 | |
| 4jey | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.467 | |
| 1a9x | ADP | Carbamoyl-phosphate synthase large chain | / | 0.466 | |
| 1gle | ADP | Glycerol kinase | / | 0.466 | |
| 1kt6 | RTL | Retinol-binding protein 4 | / | 0.466 | |
| 1ne6 | SP1 | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.466 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.466 | |
| 2i0v | 6C3 | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.466 | |
| 2xb8 | XNW | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.466 | |
| 3c15 | FOK | Adenylate cyclase type 2 | / | 0.466 | |
| 3c15 | FOK | Adenylate cyclase type 5 | / | 0.466 | |
| 3rha | FDA | Putrescine oxidase | / | 0.466 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.466 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.466 | |
| 1h5t | TYD | Glucose-1-phosphate thymidylyltransferase 1 | / | 0.465 | |
| 1w19 | T4P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.465 | |
| 2g97 | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.465 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.465 | |
| 2op0 | 7PC | Enoyl-ACP reductase | / | 0.465 | |
| 2pd7 | FAD | Vivid PAS protein VVD | / | 0.465 | |
| 2pup | ADP | Methylthioribose kinase | 2.7.1.100 | 0.465 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.465 | |
| 3ruq | ADP | Chaperonin | / | 0.465 | |
| 1dhr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.464 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 1jsc | TPP | Acetolactate synthase catalytic subunit, mitochondrial | 2.2.1.6 | 0.464 | |
| 1k27 | MTM | S-methyl-5'-thioadenosine phosphorylase | / | 0.464 | |
| 1sd1 | FMC | S-methyl-5'-thioadenosine phosphorylase | / | 0.464 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.464 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.464 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.464 | |
| 3hk1 | B64 | Fatty acid-binding protein, adipocyte | / | 0.464 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.464 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.464 | |
| 4f4q | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.464 | |
| 4fvq | ATP | Tyrosine-protein kinase JAK2 | / | 0.464 | |
| 4l4x | NDP | AmphI | / | 0.464 | |
| 4qem | HC4 | Phospholipase A2 VRV-PL-VIIIa | / | 0.464 | |
| 5fm6 | ADP | RuvB-like helicase | / | 0.464 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.464 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.463 | |
| 1ht2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.463 | |
| 2czc | NAD | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.463 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.463 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.463 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 2vjm | COA | Formyl-CoA:oxalate CoA-transferase | / | 0.463 | |
| 2zla | VDB | Vitamin D3 receptor | / | 0.463 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.463 | |
| 3n5b | ADP | Nitrogen regulatory protein P-II | / | 0.463 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.463 | |
| 4ft0 | HK9 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 4o9c | COA | Acetyl-CoA acetyltransferase | 2.3.1.9 | 0.463 | |
| 4s32 | ANP | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.463 | |
| 2bhi | SFT | Cytotoxin 3 | / | 0.462 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.462 | |
| 3qsb | 743 | Beta sliding clamp | 2.7.7.7 | 0.462 | |
| 3rdq | DTB | Streptavidin | / | 0.462 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.462 | |
| 4b8w | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.462 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.462 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.462 | |
| 5iqd | GNP | Bifunctional AAC/APH | 2.3.1 | 0.462 | |
| 5iqe | GNP | Bifunctional AAC/APH | 2.3.1 | 0.462 | |
| 1n06 | ADP | Riboflavin kinase | 2.7.1.26 | 0.461 | |
| 2pks | G44 | Prothrombin | 3.4.21.5 | 0.461 | |
| 2pzp | ACP | Fibroblast growth factor receptor 2 | / | 0.461 | |
| 2r8p | T6F | Transketolase 1 | / | 0.461 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.461 | |
| 3ae4 | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.461 | |
| 3vpb | ADP | Glutamate--LysW ligase ArgX | 6.3.2 | 0.461 | |
| 4gfv | PRO_GLU_LEU_THR_PTR | Tyrosine-protein phosphatase non-receptor type 18 | 3.1.3.48 | 0.461 | |
| 4kug | NAD | 3-hydroxybutyryl-CoA dehydrogenase | / | 0.461 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.461 | |
| 4x2d | ATP | Fic family protein putative filamentation induced by cAMP protein | / | 0.461 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.460 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.460 | |
| 1kms | LIH | Dihydrofolate reductase | 1.5.1.3 | 0.460 | |
| 1tll | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.460 | |
| 1zs6 | ADP | Nucleoside diphosphate kinase 3 | 2.7.4.6 | 0.460 | |
| 3rsr | N5P | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.460 | |
| 3u8k | 09P | Acetylcholine-binding protein | / | 0.460 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4twn | B96 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.460 | |
| 4u9a | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.460 | |
| 5fko | TDC | Tetracycline repressor protein class D | / | 0.460 | |
| 5iqg | GDP | Bifunctional AAC/APH | 2.3.1 | 0.460 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.459 | |
| 2o4r | VD5 | Vitamin D3 receptor | / | 0.459 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.459 | |
| 2w6n | OA2 | Biotin carboxylase | 6.3.4.14 | 0.459 | |
| 2z4s | ADP | Chromosomal replication initiator protein DnaA | / | 0.459 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.459 | |
| 3biz | 61E | Wee1-like protein kinase | 2.7.10.2 | 0.459 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.459 | |
| 3vhx | GTP | ADP-ribosylation factor 6 | / | 0.459 | |
| 4aut | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.459 | |
| 4g1z | 0VP | Vitamin D3 receptor A | / | 0.459 | |
| 5cp8 | TCU | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.459 | |
| 5iqa | GNP | Bifunctional AAC/APH | 2.3.1 | 0.459 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.458 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.458 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.458 | |
| 2yer | TQ1 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.458 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.458 | |
| 3b9l | AZZ | Serum albumin | / | 0.458 | |
| 3dv3 | MEK | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.458 | |
| 3tm4 | SAM | Uncharacterized protein | / | 0.458 | |
| 3up0 | D7S | aceDAF-12 | / | 0.458 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.458 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.458 | |
| 4o1p | ANP | Ribonuclease L | / | 0.458 | |
| 4r1l | ADP | Phenylacetate-coenzyme A ligase | / | 0.458 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.458 | |
| 1id0 | ANP | Sensor protein PhoQ | 2.7.13.3 | 0.457 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.457 | |
| 2cah | NDP | Catalase | 1.11.1.6 | 0.457 | |
| 2chz | 093 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 2dbr | NAP | Glyoxylate reductase | 1.1.1.26 | 0.457 | |
| 2e1z | B4P | Propionate kinase | / | 0.457 | |
| 2itu | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.457 | |
| 2rc6 | NAP | Ferredoxin--NADP reductase | / | 0.457 | |
| 2y4g | TIR | TamL | / | 0.457 | |
| 2zjw | REF | Casein kinase II subunit alpha | 2.7.11.1 | 0.457 | |
| 3am3 | TCL | Enoyl-ACP reductase | / | 0.457 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.457 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.457 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.457 | |
| 5hbs | RTL | Retinol-binding protein 1 | / | 0.457 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.456 | |
| 1p4a | PCP | Pur operon repressor | / | 0.456 | |
| 1q8y | ADP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.456 | |
| 1x8b | 824 | Wee1-like protein kinase | 2.7.10.2 | 0.456 | |
| 2cgx | 3D3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.456 | |
| 2iyp | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.456 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.456 | |
| 3p7n | FMN | Light-activated DNA-binding protein EL222 | / | 0.456 | |
| 4b6c | B5U | DNA gyrase subunit B | / | 0.456 | |
| 4tx9 | AMZ | Phosphoribosyl isomerase A | / | 0.456 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.456 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.455 | |
| 1h9z | RWF | Serum albumin | / | 0.455 | |
| 1ie8 | KH1 | Vitamin D3 receptor | / | 0.455 | |
| 1ky2 | GNP | GTP-binding protein YPT7 | / | 0.455 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.455 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.455 | |
| 2yex | YEX | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.455 | |
| 2zdt | 46C | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.455 | |
| 3gts | D3M | DdmC | / | 0.455 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 3mgd | ACO | Predicted acetyltransferase | / | 0.455 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.455 | |
| 3w0g | W07 | Vitamin D3 receptor | / | 0.455 | |
| 4bam | MM9 | Prothrombin | 3.4.21.5 | 0.455 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.455 | |
| 4btj | ATP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.455 | |
| 4c6u | TLG | 3-oxoacyl-ACP synthase | / | 0.455 | |
| 4dve | BTN | Biotin transporter BioY | / | 0.455 | |
| 4ia3 | BIV | Vitamin D3 receptor A | / | 0.455 | |
| 4kxl | 6C6 | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.455 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.455 | |
| 5dby | NPS | Serum albumin | / | 0.455 | |
| 1dqa | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.454 | |
| 1hdr | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.454 | |
| 1kt3 | RTL | Retinol-binding protein 4 | / | 0.454 | |
| 1n08 | ADP | Riboflavin kinase | 2.7.1.26 | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.454 | |
| 2baq | PQB | Mitogen-activated protein kinase 14 | / | 0.454 | |
| 2has | C3O | Vitamin D3 receptor | / | 0.454 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.454 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.454 | |
| 2z0x | 5CA | Uncharacterized protein | / | 0.454 | |
| 3ssn | MVI | Mycinamicin VI 2''-O-methyltransferase | / | 0.454 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.454 | |
| 4awp | 99A | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.454 | |
| 4gu9 | 4GU | Focal adhesion kinase 1 | 2.7.10.2 | 0.454 | |
| 4hmv | WUB | Phenazine biosynthesis protein PhzG | 1.4 | 0.454 | |
| 4kqq | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.454 | |
| 4or0 | NPS | Serum albumin | / | 0.454 | |
| 4prv | ADP | DNA gyrase subunit B | / | 0.454 | |
| 5cvc | PLP | Serine racemase | / | 0.454 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.453 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.453 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.453 | |
| 1e1m | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.453 | |
| 1fpq | SAM | Isoliquiritigenin 2'-O-methyltransferase | / | 0.453 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.453 | |
| 1o1v | TCH | Gastrotropin | / | 0.453 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.453 | |
| 1sri | DMB | Streptavidin | / | 0.453 | |
| 2kce | D16 | Thymidylate synthase | / | 0.453 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.453 | |
| 2r7b | 253 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 2xyu | Q9G | Ephrin type-A receptor 4 | 2.7.10.1 | 0.453 | |
| 3bi6 | 396 | Wee1-like protein kinase | 2.7.10.2 | 0.453 | |
| 3cr0 | 809 | Wee1-like protein kinase | 2.7.10.2 | 0.453 | |
| 3ule | C69 | Actin-related protein 3 | / | 0.453 | |
| 4bgb | ADP | Predicted molecular chaperone distantly related to HSP70-fold metalloproteases | / | 0.453 | |
| 4el5 | D1M | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.453 | |
| 4fhh | 0U3 | Vitamin D3 receptor A | / | 0.453 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.452 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.452 | |
| 1srf | MTB | Streptavidin | / | 0.452 | |
| 1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.452 | |
| 1tll | FAD | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.452 | |
| 2c59 | NAD | GDP-mannose 3,5-epimerase | 5.1.3.18 | 0.452 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 2i1m | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.452 | |
| 2jfz | 003 | Glutamate racemase | / | 0.452 | |
| 3k8t | DGT | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.452 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.452 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.452 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.452 | |
| 1cbs | REA | Cellular retinoic acid-binding protein 2 | / | 0.451 | |
| 1cgz | STL | Chalcone synthase 2 | 2.3.1.74 | 0.451 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.451 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.451 | |
| 1pq9 | 44B | Oxysterols receptor LXR-beta | / | 0.451 | |
| 1q4l | 679 | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.451 | |
| 2b4r | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.451 | |
| 2gcg | NDP | Glyoxylate reductase/hydroxypyruvate reductase | 1.1.1.79 | 0.451 | |
| 2i0y | 5CN | Macrophage colony-stimulating factor 1 receptor | 2.7.10.1 | 0.451 | |
| 2r8o | T5X | Transketolase 1 | / | 0.451 | |
| 2w3m | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 3cbs | R12 | Cellular retinoic acid-binding protein 2 | / | 0.451 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.451 | |
| 3h3j | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.451 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.451 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.451 | |
| 4dsu | GDP | GTPase KRas | / | 0.451 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.451 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.451 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.451 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.450 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.450 | |
| 1fnd | A2P | Ferredoxin--NADP reductase, chloroplastic | 1.18.1.2 | 0.450 | |
| 1jgt | APC | Carboxyethyl-arginine beta-lactam-synthase | 6.3.3.4 | 0.450 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.450 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.450 | |
| 2btd | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.450 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.450 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 3jun | AJD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 3rye | UNR | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.450 | |
| 3ukr | CKH | Actin-related protein 3 | / | 0.450 | |
| 3ukr | CKH | Actin-related protein 2 | / | 0.450 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.450 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.450 | |
| 4egn | TWO | Cytochrome P450 | / | 0.450 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.450 | |
| 4mob | COA | Acyl-coenzyme A thioesterase 12 | 3.1.2.1 | 0.450 | |
| 4ubv | COA | Steroid 3-ketoacyl-CoA thiolase | / | 0.450 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.450 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.450 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.449 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.449 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.449 | |
| 1zzl | TZY | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 2b55 | D31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 2cul | FAD | GidA-related protein | / | 0.449 | |
| 2oz6 | CMP | Cyclic AMP receptor-like protein | / | 0.449 | |
| 2pdt | FAD | Vivid PAS protein VVD | / | 0.449 | |
| 2pz5 | ACP | Fibroblast growth factor receptor 2 | / | 0.449 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.449 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.449 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.449 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.449 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.449 | |
| 3s87 | DGT | Ribonucleoside-diphosphate reductase large chain 1 | 1.17.4.1 | 0.449 | |
| 3t4h | MD5 | Alpha-ketoglutarate-dependent dioxygenase AlkB | 1.14.11.33 | 0.449 | |
| 4b0c | C9H | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.449 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.449 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.449 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.449 | |
| 4wqm | FAD | Toluene-4-monooxygenase electron transfer component | 1.18.1.3 | 0.449 | |
| 4xiv | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.449 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.449 | |
| 5hwr | COA | Hydroxymethylglutaryl-CoA synthase | / | 0.449 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.448 | |
| 1lev | CLI | Fructose-1,6-bisphosphatase 1 | 3.1.3.11 | 0.448 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.448 | |
| 1z48 | FMN | NADPH dehydrogenase | / | 0.448 | |
| 2ej2 | PPE | Branched-chain amino acid aminotransferase (IlvE) | / | 0.448 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.448 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.448 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.448 | |
| 2pr5 | FMN | Blue-light photoreceptor | / | 0.448 | |
| 2qf2 | GDP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.448 | |
| 3baz | NAP | Hydroxyphenylpyruvate reductase | 1.1.1.237 | 0.448 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 3s79 | ASD | Aromatase | 1.14.14.14 | 0.448 | |
| 3tm5 | SFG | Uncharacterized protein | / | 0.448 | |
| 3wqu | ATP | Cell division protein FtsA | / | 0.448 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.448 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.448 | |
| 4co4 | ATP | Nitrogen regulatory protein P-II 1 | / | 0.448 | |
| 4dvi | 2IW | Tankyrase-1 | 2.4.2.30 | 0.448 | |
| 4ho9 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.448 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.448 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.447 | |
| 1z2n | ADP | Inositol-tetrakisphosphate 1-kinase | 2.7.1.134 | 0.447 | |
| 2bal | PQA | Mitogen-activated protein kinase 14 | / | 0.447 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.447 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.447 | |
| 2izf | BTN | Streptavidin | / | 0.447 | |
| 2nvb | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.447 | |
| 2pd8 | FAD | Vivid PAS protein VVD | / | 0.447 | |
| 2vr1 | ATF | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 2yx6 | ADP | Uncharacterized protein | / | 0.447 | |
| 3ahi | HTL | Probable phosphoketolase | / | 0.447 | |
| 3c15 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.447 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.447 | |
| 3gkj | HC3 | Niemann-Pick C1 protein | / | 0.447 | |
| 3oq1 | 3OQ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.447 | |
| 3p23 | ADP | Serine/threonine-protein kinase/endoribonuclease IRE1 | 2.7.11.1 | 0.447 | |
| 3p84 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.447 | |
| 3zly | YSO | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.447 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.447 | |
| 4c73 | TLH | 3-oxoacyl-ACP synthase | / | 0.447 | |
| 4cf7 | ADP | Adenylate kinase | / | 0.447 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.447 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.447 | |
| 4jbx | SK7 | Thymidine kinase | / | 0.447 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.447 | |
| 4l9q | 9TP | Serum albumin | / | 0.447 | |
| 1ao0 | 5GP | Amidophosphoribosyltransferase | / | 0.446 | |
| 1e3w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.446 | |
| 1e94 | ANP | ATP-dependent protease ATPase subunit HslU | / | 0.446 | |
| 1fw0 | KAI | Glutamate receptor 2 | / | 0.446 | |
| 1l4m | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.446 | |
| 1m67 | BOA | Glycerol-3-phosphate dehydrogenase [NAD(+)], glycosomal | 1.1.1.8 | 0.446 | |
| 1rj9 | GCP | Signal recognition particle receptor FtsY | / | 0.446 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.446 | |
| 1yti | PHE_LEU_GLU_LYS | Gag-Pol polyprotein | / | 0.446 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.446 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.446 | |
| 2gvd | FKP | Adenylate cyclase type 2 | / | 0.446 | |
| 2gvd | FKP | Adenylate cyclase type 5 | / | 0.446 | |
| 2jlb | UDM | Uncharacterized protein | / | 0.446 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.446 | |
| 3e92 | G6A | Mitogen-activated protein kinase 14 | / | 0.446 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.446 | |
| 3gc9 | B45 | Mitogen-activated protein kinase 11 | 2.7.11.24 | 0.446 | |
| 3l3r | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.446 | |
| 3r8u | Z31 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.446 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.446 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.446 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.446 | |
| 4gnc | ASO | Regucalcin | 3.1.1.17 | 0.446 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.446 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.446 | |
| 4hxy | NDP | Plm1 | / | 0.446 | |
| 4l8u | 9AZ | Serum albumin | / | 0.446 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.446 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.446 | |
| 4yaf | 2AM | NADPH--cytochrome P450 reductase | / | 0.446 | |
| 5dbv | COA | Aldehyde Dehydrogenase | / | 0.446 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.446 | |
| 5iu8 | 6DZ | Adenosine receptor A2a | / | 0.446 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.445 | |
| 1il0 | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.445 | |
| 1j91 | TBS | Casein kinase II subunit alpha | 2.7.11.1 | 0.445 | |
| 1mdl | RMN | Mandelate racemase | / | 0.445 | |
| 1ny3 | ADP | MAP kinase-activated protein kinase 2 | 2.7.11.1 | 0.445 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.445 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.445 | |
| 1w19 | T1P | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.445 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.445 | |
| 2bf4 | NAP | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 2ceo | T44 | Thyroxine-binding globulin | / | 0.445 | |
| 2e2q | ADP | ATP-dependent hexokinase | / | 0.445 | |
| 2glx | NDP | 1,5-anhydro-D-fructose reductase | / | 0.445 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.445 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.445 | |
| 2ohh | FMN | Type A flavoprotein FprA | 1 | 0.445 | |
| 2xf3 | J01 | Uncharacterized protein | / | 0.445 | |
| 2xgo | ZKD | Uncharacterized protein | / | 0.445 | |
| 2xka | GSP | Cell division protein FtsZ | / | 0.445 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.445 | |
| 3cvy | FAD | RE11660p | / | 0.445 | |
| 3d7t | STU | Tyrosine-protein kinase CSK | / | 0.445 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.445 | |
| 3eq0 | 2TS | Prothrombin | 3.4.21.5 | 0.445 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.445 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.445 | |
| 3qfr | NAP | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 4eh5 | IRG | Mitogen-activated protein kinase 14 | / | 0.445 | |
| 4elg | 52J | Dihydrofolate reductase | / | 0.445 | |
| 4hj4 | FMN | LOV protein | / | 0.445 | |
| 4ku2 | MYA | 3-oxoacyl-[ACP] synthase III | / | 0.445 | |
| 4mv3 | ACP | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.445 | |
| 5bt9 | NAP | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.445 | |
| 5e9w | SAH | mRNA cap guanine-N7 methyltransferase | 2.1.1.56 | 0.445 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.444 | |
| 1g6c | IFP | Thiamine-phosphate synthase | / | 0.444 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.444 | |
| 1j8u | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.444 | |
| 1kt7 | RTL | Retinol-binding protein 4 | / | 0.444 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.444 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.444 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 2dbq | NAP | Glyoxylate reductase | 1.1.1.26 | 0.444 | |
| 2f2s | COA | Acetyl-CoA acetyltransferase, mitochondrial | 2.3.1.9 | 0.444 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.444 | |
| 2itt | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2j9g | ADP | Biotin carboxylase | 6.3.4.14 | 0.444 | |
| 2q7h | YLY | Pyrrolysine--tRNA ligase | / | 0.444 | |
| 2qll | PLP | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.444 | |
| 2vqb | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2vwu | 7X1 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 2xvv | 9DN | Serum albumin | / | 0.444 | |
| 3dj4 | UD1 | Bifunctional protein GlmU | / | 0.444 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.444 | |
| 3mje | NDP | AmphB | / | 0.444 | |
| 3nuy | JPZ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 3uxy | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.444 | |
| 3vwe | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.444 | |
| 3zp4 | TSA | Chorismate mutase AroH | 5.4.99.5 | 0.444 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.444 | |
| 4bak | M67 | Prothrombin | 3.4.21.5 | 0.444 | |
| 4btj | ADP | Tau-tubulin kinase 1 | 2.7.11.1 | 0.444 | |
| 4dh3 | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 4dpm | COA | Malonyl-CoA reductase | 1.2.1.75 | 0.444 | |
| 4lga | A2O | Abscisic acid receptor PYL2 | / | 0.444 | |
| 4nfs | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.444 | |
| 1bmk | SB5 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 1ef9 | 2CP | Methylmalonyl-CoA decarboxylase | 4.1.1.41 | 0.443 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.443 | |
| 1mqe | APR | MutT/nudix family protein | / | 0.443 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.443 | |
| 1rc1 | KT3 | Trifunctional purine biosynthetic protein adenosine-3 | 2.1.2.2 | 0.443 | |
| 1rl3 | PCG | cAMP-dependent protein kinase type I-alpha regulatory subunit | / | 0.443 | |
| 1sre | HAB | Streptavidin | / | 0.443 | |
| 2b56 | UTP | RNA editing complex protein MP57 | / | 0.443 | |
| 2bl9 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.443 | |
| 2cfc | KPC | 2-(R)-hydroxypropyl-CoM dehydrogenase | 1.1.1.268 | 0.443 | |
| 2fr3 | REA | Cellular retinoic acid-binding protein 2 | / | 0.443 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.443 | |
| 3d2r | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.443 | |
| 3fwf | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 3nsz | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 3nyt | ULP | UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase | 2.6.1.98 | 0.443 | |
| 3o9p | MHI | Periplasmic murein peptide-binding protein | / | 0.443 | |
| 3rep | ATP | Integrin-linked protein kinase | 2.7.11.1 | 0.443 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3rv9 | RVD | Salicylate synthase | / | 0.443 | |
| 3vhu | SNL | Mineralocorticoid receptor | / | 0.443 | |
| 3x2v | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 3zkn | WZV | Beta-secretase 2 | 3.4.23.45 | 0.443 | |
| 4c59 | FEF | Cyclin-G-associated kinase | 2.7.11.1 | 0.443 | |
| 4dg3 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.443 | |
| 4emt | C2E | Stimulator of interferon genes protein | / | 0.443 | |
| 4f1m | ACP | Probable serine/threonine-protein kinase roco4 | 2.7.11.1 | 0.443 | |
| 4k36 | SAM | Anaerobic sulfatase-maturating enzyme | 1.8.98 | 0.443 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.443 | |
| 4xum | IMN | Peroxisome proliferator-activated receptor gamma | / | 0.443 | |
| 5cvh | ADP | Casein kinase II subunit alpha | 2.7.11.1 | 0.443 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.442 | |
| 1cbf | SAH | Cobalt-precorrin-4 C(11)-methyltransferase | 2.1.1.271 | 0.442 | |
| 1lwx | AZD | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.442 | |
| 1mf0 | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.442 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.442 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.442 | |
| 2egl | SAH | Diphthine synthase | / | 0.442 | |
| 2g2f | AGS | Tyrosine-protein kinase ABL1 | 2.7.10.2 | 0.442 | |
| 2r5n | TPP | Transketolase 1 | / | 0.442 | |
| 2vkd | UPG | Cytotoxin L | / | 0.442 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.442 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.442 | |
| 2zb4 | 5OP | Prostaglandin reductase 2 | 1.3.1.48 | 0.442 | |
| 3atz | FMN | Prostaglandin F2a synthase | / | 0.442 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.442 | |
| 3dol | GWI | Pol protein | / | 0.442 | |
| 3fjq | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3iw1 | ASD | Steroid C26-monooxygenase | 1.14.13.141 | 0.442 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.442 | |
| 3nh8 | DC2 | N-acyl-aromatic-L-amino acid amidohydrolase (carboxylate-forming) | 3.5.1.114 | 0.442 | |
| 3p17 | 99P | Prothrombin | 3.4.21.5 | 0.442 | |
| 3q5k | D1U | Heat shock protein 83-1 | / | 0.442 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 3sqz | COA | Putative hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 3w5q | 3KL | Vitamin D3 receptor | / | 0.442 | |
| 4a6a | TTP | dCTP deaminase | 3.5.4.13 | 0.442 | |
| 4dju | 0KK | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4e03 | ADP | Plasmid partitioning protein ParF | / | 0.442 | |
| 4e2d | FMN | Dehydrogenase | / | 0.442 | |
| 4e37 | NDP | Catalase | 1.11.1.6 | 0.442 | |
| 4hyu | 1BK | Mitogen-activated protein kinase 8 | 2.7.11.24 | 0.442 | |
| 4k33 | ACP | Fibroblast growth factor receptor 3 | 2.7.10.1 | 0.442 | |
| 4pao | GSP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.442 | |
| 4qna | X11 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.442 | |
| 4rup | H97 | Vitamin D3 receptor A | / | 0.442 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 4yao | 2AM | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.442 | |
| 5ccy | TMP | Polymerase acidic protein | / | 0.442 | |
| 5iu4 | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1bmf | ADP | ATP synthase subunit alpha, mitochondrial | / | 0.441 | |
| 1bmf | ADP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.441 | |
| 1boz | PRD | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1cjv | DAD | Adenylate cyclase type 2 | / | 0.441 | |
| 1cjv | DAD | Adenylate cyclase type 5 | / | 0.441 | |
| 1gld | ADP | Glycerol kinase | / | 0.441 | |
| 1j7k | ATP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.441 | |
| 1l5o | NCN | Nicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase | 2.4.2.21 | 0.441 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.441 | |
| 1uv5 | BRW | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.441 | |
| 1uyk | PUX | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 1xjn | DTP | Vitamin B12-dependent ribonucleotide reductase | / | 0.441 | |
| 1zsn | TN2 | Enoyl-ACP reductase | / | 0.441 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.441 | |
| 2bdy | UNB | Prothrombin | 3.4.21.5 | 0.441 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.441 | |
| 2c3p | 1TP | Pyruvate synthase | / | 0.441 | |
| 2el0 | SAH | Diphthine synthase | / | 0.441 | |
| 2ep7 | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.441 | |
| 2in6 | 839 | Wee1-like protein kinase | 2.7.10.2 | 0.441 | |
| 2itz | IRE | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 2qg2 | A91 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2uz2 | BTN | Avd protein | / | 0.441 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2ym4 | 4YM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ym8 | YM8 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 3e6y | CW1 | 14-3-3-like protein C | / | 0.441 | |
| 3ge1 | ADP | Glycerol kinase | / | 0.441 | |
| 3l06 | SN0 | N-acetylornithine carbamoyltransferase | 2.1.3.9 | 0.441 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 3pnl | ADP | PEP-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL | 2.7 | 0.441 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.441 | |
| 4biz | ADP | Sensor histidine kinase CpxA | / | 0.441 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.441 | |
| 4eer | FMN | Phototropin-2 | 2.7.11.1 | 0.441 | |
| 4hj6 | FMN | LOV protein | / | 0.441 | |
| 4i3z | ADP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.441 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.441 | |
| 4nd3 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.441 | |
| 4okw | 198 | Androgen receptor | / | 0.441 | |
| 4xiv | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 5c4c | UPG | Histo-blood group ABO system transferase | / | 0.441 | |
| 5dto | SAH | Genome polyprotein | / | 0.441 | |
| 1bxr | ANP | Carbamoyl-phosphate synthase large chain | / | 0.440 | |
| 1c3e | GAR | Phosphoribosylglycinamide formyltransferase | / | 0.440 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.440 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.440 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.440 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.440 | |
| 1dhi | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.440 | |
| 1noo | CAH | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.440 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.440 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.440 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.440 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.440 | |
| 1xve | 3BB | Methane monooxygenase component A beta chain | 1.14.13.25 | 0.440 | |
| 1y52 | BTN | Avidin-related protein 4/5 | / | 0.440 | |
| 2ea1 | GPG | Ribonuclease I | 3.1.27.6 | 0.440 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.440 | |
| 2izh | BTN | Streptavidin | / | 0.440 | |
| 2j8z | NAP | Quinone oxidoreductase PIG3 | 1 | 0.440 | |
| 2l84 | J28 | CREB-binding protein | / | 0.440 | |
| 2npn | SAM | Putative cobalamin synthesis related protein | / | 0.440 | |
| 2qu5 | 276 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.440 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.440 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.440 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.440 | |
| 3cmp | EB4 | Neutrophil gelatinase-associated lipocalin | / | 0.440 | |
| 3d2m | COA | Amino-acid acetyltransferase | / | 0.440 | |
| 3e8c | G96 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 3h3f | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.440 | |
| 3njo | P2M | Abscisic acid receptor PYR1 | / | 0.440 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.440 | |
| 3u0z | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 1 | / | 0.440 | |
| 3uqd | ADP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.440 | |
| 3v3m | 0EN | Replicase polyprotein 1a | 3.4.19.12 | 0.440 | |
| 4a2b | AGS | Cell division protein FtsA | / | 0.440 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.440 | |
| 4ba5 | PXG | Probable aminotransferase | / | 0.440 | |
| 4bdh | WVI | Serine/threonine-protein kinase Chk2 | 2.7.11.1 | 0.440 | |
| 4hia | FMN | LOV protein | / | 0.440 | |
| 4i9b | NAD | Putative betaine aldehyde dehyrogenase | / | 0.440 | |
| 4iad | ADP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.440 | |
| 4jc5 | 1K5 | Stimulator of interferon genes protein | / | 0.440 | |
| 4kwi | 1TJ | Reductase homolog | / | 0.440 | |
| 4lj9 | ACP | Chaperone protein ClpB | / | 0.440 | |
| 4m6l | 21V | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 4mzu | TYD | WxcM-like protein | / | 0.440 |