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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
4ho4THMGlucose-1-phosphate thymidylyltransferase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
4ho4THMGlucose-1-phosphate thymidylyltransferase/1.000
4ho9UTPGlucose-1-phosphate thymidylyltransferase/0.602
4ho8THMGlucose-1-phosphate thymidylyltransferase/0.598
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.552
1fxoTMPGlucose-1-phosphate thymidylyltransferase/0.551
5ifyUMPGlucose-1-phosphate thymidylyltransferase/0.534
4dpwAGSMevalonate diphosphate decarboxylase/0.521
1h5tTYDGlucose-1-phosphate thymidylyltransferase 1/0.513
3w2wATPCRISPR system Cmr subunit Cmr2/0.513
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.510
2getCOKPantothenate kinase2.7.1.330.508
3v2uATPProtein GAL3/0.506
3d8vUD1Bifunctional protein GlmU/0.500
4bfsZVSPantothenate kinase2.7.1.330.497
1i59ANPChemotaxis protein CheA2.7.13.30.496
2gesCOKPantothenate kinase2.7.1.330.496
2osbAP5Adenylate kinase/0.492
4c77N01Phenylacetone monooxygenase1.14.13.920.492
2geuCOKPantothenate kinase2.7.1.330.491
1h51FMNPentaerythritol tetranitrate reductase/0.489
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.489
2q5g1FAPeroxisome proliferator-activated receptor delta/0.488
2ev9NAPShikimate dehydrogenase (NADP(+))/0.487
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.485
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.484
4b8zGDPGDP-L-fucose synthase1.1.1.2710.483
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.483
2gevCOKPantothenate kinase2.7.1.330.482
3gobHXXDdmC/0.482
1nzdUPGDNA beta-glucosyltransferase/0.481
2fj1CTCTetracycline repressor protein class D/0.481
4asyN5YGlucose-1-phosphate thymidylyltransferase/0.481
1qxoFMNChorismate synthase/0.480
2eixFADNADH-cytochrome b5 reductase/0.480
2w6qOA5Biotin carboxylase6.3.4.140.479
1i5cADPChemotaxis protein CheA2.7.13.30.478
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.478
3i2834NBifunctional epoxide hydrolase 23.3.2.100.477
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.477
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.476
1ybmNAPUncharacterized protein At5g02240/0.476
2b9wFADPutative aminooxidase/0.476
2qtvGNPSmall COPII coat GTPase SAR13.6.50.476
4jbiNDPAlcohol dehydrogenase (Zinc)/0.476
5kghACOPredicted acetyltransferase/0.476
1e3eNAIAlcohol dehydrogenase 41.1.1.10.475
2w98P1ZProstaglandin reductase 21.3.1.480.475
3nl6TPSUncharacterized protein/0.475
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.474
4iqkIQKKelch-like ECH-associated protein 1/0.474
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.474
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.473
3pqbVGPPutative oxidoreductase/0.473
4a8v2ANMajor pollen allergen Bet v 1-J/0.473
4fhj0TZPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.472
4fj0NAP17beta-hydroxysteroid dehydrogenase/0.471
5kgpACOPredicted acetyltransferase/0.471
1qmgAPXKetol-acid reductoisomerase, chloroplastic1.1.1.860.470
2z3uCRRCytochrome P450/0.470
2z4zSC0Geranylgeranyl pyrophosphate synthase/0.470
3oqfS51Renin3.4.23.150.470
3vglANPGlucokinase/0.470
4ifn12OKelch-like ECH-associated protein 1/0.470
4ryvZEAProtein LlR18A/0.470
1lf3EH5Plasmepsin-23.4.23.390.469
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.469
3nbvANPKetohexokinase/0.469
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.468
1nlmUD1UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase/0.468
3af1GDPPantothenate kinase2.7.1.330.468
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.468
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.468
1w6hTITPlasmepsin-23.4.23.390.467
2bmbPMMFolic acid synthesis protein FOL1/0.467
2y3sTIRTamL/0.467
3keuATPPyridoxal kinase2.7.1.350.467
4ipw1G7Mycocyclosin synthase1.14.21.90.467
5dq8FLFTranscriptional enhancer factor TEF-4/0.467
5kczNAJAlcohol dehydrogenase E chain1.1.1.10.467
1jm6ADP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.466
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
2abbFMNPentaerythritol tetranitrate reductase/0.466
2x0iNAIMalate dehydrogenase/0.466
4fehFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.466
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.466
4uymVOR14-alpha sterol demethylase Cyp51B/0.466
1in5ADPHolliday junction ATP-dependent DNA helicase RuvB/0.465
1nvtNAPShikimate dehydrogenase (NADP(+))/0.465
2ft9CHDFatty acid-binding protein 2, liver/0.465
2rkvZBATrichothecene 3-O-acetyltransferase/0.465
3lovFADProtoporphyrinogen oxidase/0.465
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.465
4gxs0YSGlutamate receptor 2/0.465
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.465
5bn3ADPV-type ATP synthase alpha chain/0.465
5bn3ADPNEQ263/0.465
1ipeNDPTropinone reductase 21.1.1.2360.464
2ebaFADPutative glutaryl-CoA dehydrogenase/0.464
2xrwANPMitogen-activated protein kinase 82.7.11.240.464
2zsaADPPantothenate kinase2.7.1.330.464
2zsdCOAPantothenate kinase2.7.1.330.464
3lmgANPReceptor tyrosine-protein kinase erbB-32.7.10.10.464
3s1dZIRCytokinin dehydrogenase 11.5.99.120.464
3tdl11DSerum albumin/0.464
3tnlNADShikimate dehydrogenase (NADP(+))/0.464
3ttjJBIMitogen-activated protein kinase 102.7.11.240.464
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.464
5dbfNDPIridoid synthase1.3.1.990.464
1l7eNAINAD(P) transhydrogenase subunit alpha part 11.6.1.20.463
1orrCDPCDP-paratose 2-epimerase/0.463
2qo4CHDFatty acid-binding protein 10-A, liver basic/0.463
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.463
3zh8C58Protein kinase C iota type2.7.11.130.463
4okx198Androgen receptor/0.463
4oviN01Phenylacetone monooxygenase1.14.13.920.463
1rx0FADIsobutyryl-CoA dehydrogenase, mitochondrial1.3.990.462
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.462
4b3aTACTetracycline repressor protein class D/0.462
1h6vNDPThioredoxin reductase 1, cytoplasmic1.8.1.90.461
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.461
2v5aLZLBiotin carboxylase6.3.4.140.461
2vn0TDZCytochrome P450 2C8/0.461
2xpwOTCTetracycline repressor protein class D/0.461
2xvfFADPutative flavin-containing monooxygenase/0.461
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.461
4c1mNIHMyeloperoxidase1.11.2.20.461
4oznATPAmmonium transporter/0.461
4q71FADBifunctional protein PutA/0.461
1vyrFMNPentaerythritol tetranitrate reductase/0.460
2bxoOPBSerum albumin/0.460
2fhnBNIAvidin-related protein 4/5/0.460
2oz57XYUncharacterized protein/0.460
2rl1UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.460
2znq401Peroxisome proliferator-activated receptor delta/0.460
4wriOKAOkadaic acid binding protein 2-alpha/0.460
1ih8APCNH(3)-dependent NAD(+) synthetase6.3.1.50.459
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.459
2vkeTACTetracycline repressor protein class D/0.459
3bac3B9DNA ligase/0.459
3gwfFADCyclohexanone monooxygenase/0.459
3vmmP0DAlanine--anticapsin ligase/0.459
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.459
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.459
4n9iPCGCatabolite expression activator/0.459
4wjiNAPPutative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase/0.459
5jscFADPutative acyl-CoA dehydrogenase/0.459
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.459
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.458
2dt5NADRedox-sensing transcriptional repressor Rex/0.458
2zevB71Geranylgeranyl pyrophosphate synthase/0.458
3gf4UPGUDP-galactopyranose mutase5.4.99.90.458
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.458
4loh1SYStimulator of interferon genes protein/0.458
4oagADPMitochondrial dynamics protein MID51/0.458
4v2gITCTetracycline repressor protein class D/0.458
5kf1ACOPredicted acetyltransferase/0.458
1bk0ACVIsopenicillin N synthase1.21.3.10.457
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.457
1j39UPGDNA beta-glucosyltransferase/0.457
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.457
3cukFADD-amino-acid oxidase1.4.3.30.457
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.457
3ge1ADPGlycerol kinase/0.457
3r5yF42Uncharacterized protein/0.457
4l9q9TPSerum albumin/0.457
4ocvANPAminoglycoside phosphotransferase/0.457
1mf0GDPAdenylosuccinate synthetase isozyme 1/0.456
1rj6AZMCarbonic anhydrase 144.2.1.10.456
1rydNDPGlucose--fructose oxidoreductase1.1.99.280.456
2am22LGUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.456
2dxvSAHDiphthine synthase/0.456
2ed4NAD4-hydroxyphenylacetate 3-monooxygenase reductase component1.5.1.360.456
2iko7IGRenin3.4.23.150.456
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.456
2xlpFADPutative flavin-containing monooxygenase/0.456
3eej53RUncharacterized protein/0.456
3fnlSHALactoperoxidase/0.456
4fryNADPutative signal-transduction protein with CBS domains/0.456
4xnw2IDP2Y purinoceptor 1/0.456
1cjkFOKAdenylate cyclase type 2/0.455
1cjkFOKAdenylate cyclase type 5/0.455
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1i7lATPSynapsin-2/0.455
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
2hcdBIVVitamin D3 receptor A/0.455
2yxuATPPyridoxal kinase2.7.1.350.455
2z9dFMNFMN-dependent NADH-azoreductase/0.455
3dhcCYKN-acyl homoserine lactonase AiiA3.1.1.810.455
3fhyATPPyridoxal kinase2.7.1.350.455
3id8MRKGlucokinase2.7.1.20.455
3mgdACOPredicted acetyltransferase/0.455
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.455
3p62FMNPentaerythritol tetranitrate reductase/0.455
3q43D66M1 family aminopeptidase3.4.110.455
3rqqBA3ADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.455
4fidGDPG protein alpha subunit, putative/0.455
5eowFAD6-hydroxynicotinate 3-monooxygenase1.14.13.1140.455
1bwkFMNNADPH dehydrogenase 11.6.99.10.454
1g4tFTPThiamine-phosphate synthase/0.454
1mezGDPAdenylosuccinate synthetase isozyme 1/0.454
1t9gFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.454
1u3vNADAlcohol dehydrogenase 1B1.1.1.10.454
1w48APCNTPase P4/0.454
1x8lOXRRetinol dehydratase/0.454
2ejvNADL-threonine 3-dehydrogenase/0.454
2jb4A14Isopenicillin N synthase1.21.3.10.454
2oorNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.454
2pg0FADAcyl-CoA dehydrogenase/0.454
2rghFADAlpha-Glycerophosphate Oxidase/0.454
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.454
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.454
4g3pUD1Bifunctional protein GlmU/0.454
4lez1SYCyclic GMP-AMP synthase/0.454
1rf7DHFDihydrofolate reductase1.5.1.30.453
1udaUFGUDP-glucose 4-epimerase5.1.3.20.453
2fzwNADAlcohol dehydrogenase class-31.1.1.10.453
2gjlFMNNitronate monooxygenase1.13.12.160.453
2py7ATPPhosphoenolpyruvate carboxykinase (ATP)/0.453
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.453
2zbaZBATrichothecene 3-O-acetyltransferase/0.453
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.453
2zshGA3Gibberellin receptor GID1A30.453
3adaNADSubunit alpha of sarocosine oxidase/0.453
3d8bADPFidgetin-like protein 13.6.40.453
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.453
3dj4UD1Bifunctional protein GlmU/0.453
3mdmFJZCholesterol 24-hydroxylase/0.453
4ambDUDPutative glycosyl transferase/0.453
4h6kFMNNADPH dehydrogenase 11.6.99.10.453
4n57ADPAPH(2'')-Id/0.453
4r3kCOAN-alpha-acetyltransferase2.3.10.453
4tyqAP5Adenylate kinase/0.453
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.453
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.453
1cjtFOKAdenylate cyclase type 2/0.452
1cjtFOKAdenylate cyclase type 5/0.452
1lf2R37Plasmepsin-23.4.23.390.452
1r2jFADFkbI/0.452
1z48FMNNADPH dehydrogenase/0.452
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.452
2eglSAHDiphthine synthase/0.452
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.452
2w6oOA3Biotin carboxylase6.3.4.140.452
2wi5ZZ5Heat shock protein HSP 90-alpha/0.452
2ylwNAPPhenylacetone monooxygenase1.14.13.920.452
2zjmF1MBeta-secretase 13.4.23.460.452
3cavCI23-oxo-5-beta-steroid 4-dehydrogenase/0.452
3g1rFIT3-oxo-5-beta-steroid 4-dehydrogenase/0.452
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.452
3p67FMNPentaerythritol tetranitrate reductase/0.452
4a99FADTetX family tetracycline inactivation enzyme/0.452
4i8vBHFCytochrome P450 1A11.14.14.10.452
4if5ACOAlpha-tubulin N-acetyltransferase 1/0.452
4jx1CAHCamphor 5-monooxygenase1.14.15.10.452
4qnyANPMitogen activated protein kinase, putative/0.452
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.452
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.452
1u3dFADCryptochrome-1/0.451
2ou5FMNPyridoxamine 5'-phosphate oxidase-related FMN-binding protein/0.451
2q5p241Peroxisome proliferator-activated receptor gamma/0.451
2qo6CHDFatty acid-binding protein 10-A, liver basic/0.451
2qocANPEphrin type-A receptor 32.7.10.10.451
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.451
2r4tADPGlycogen synthase2.4.1.210.451
2w9hTOPDihydrofolate reductase1.5.1.30.451
2xlsFADPutative flavin-containing monooxygenase/0.451
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.451
3tz3B36Acetyl-CoA carboxylase/0.451
3u9eCOALmo1369 protein/0.451
3zhrTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.451
4aknS5BBromodomain-containing protein 2/0.451
4fxy0W2Neurolysin, mitochondrial3.4.24.160.451
4g3qUD1Bifunctional protein GlmU/0.451
4gk2L66Ephrin type-A receptor 32.7.10.10.451
4yryFADGlutamate synthase, beta subunit/0.451
5cdsNAJAlcohol dehydrogenase E chain1.1.1.10.451
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.450
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.450
2hayFMNPutative NAD(P)H-flavin oxidoreductase/0.450
2o12FMNChorismate synthase/0.450
2oapANPType II secretion system protein (GspE-2)/0.450
2ohxNADAlcohol dehydrogenase E chain1.1.1.10.450
2qo9ANPEphrin type-A receptor 32.7.10.10.450
2vprTDCTetracycline repressor protein class H/0.450
2xx91NFGlutamate receptor 2/0.450
2znpK55Peroxisome proliferator-activated receptor delta/0.450
3af4GCPPantothenate kinase2.7.1.330.450
3crzFADFerredoxin--NADP+ reductase/0.450
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.450
3p8iFMNPentaerythritol tetranitrate reductase/0.450
3q33ACOHistone acetyltransferase RTT1092.3.1.480.450
3w1rMRODihydroorotate dehydrogenase (fumarate)1.3.98.10.450
4yl2FMNLactate oxidase/0.450
1dhrNADDihydropteridine reductase1.5.1.340.449
1qiqACCIsopenicillin N synthase1.21.3.10.449
1rkxNADCDP-D-glucose-4,6-dehydratase/0.449
1vzdCB3Thymidylate synthase/0.449
1ygkRRCPyridoxal kinase2.7.1.350.449
1zgaHMKIsoflavone 4'-O-methyltransferase/0.449
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.449
2cy0NAPShikimate dehydrogenase (NADP(+))/0.449
2hk9NAPShikimate dehydrogenase (NADP(+))/0.449
2qoqANPEphrin type-A receptor 32.7.10.10.449
3af0GDPPantothenate kinase2.7.1.330.449
3ahiHTLProbable phosphoketolase/0.449
3dmeFADPutative conserved exported protein/0.449
3hkoANPCalcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands/0.449
3oqkS52Renin3.4.23.150.449
3qftNAPNADPH--cytochrome P450 reductase/0.449
3ql6NIMLactoperoxidase1.11.1.70.449
3t3r9PLCytochrome P450 2A61.14.130.449
3zvmADPBifunctional polynucleotide phosphatase/kinase2.7.1.780.449
4b4dFADFerredoxin-NADP reductase/0.449
4hjfC2EGGDEF family protein/0.449
4hwkNAPSepiapterin reductase1.1.1.1530.449
4i6gFADCryptochrome-2/0.449
4iae1DXAlr2278 protein/0.449
4kcfAKMFAD-dependent oxidoreductase/0.449
4nxxGDPMitochondrial dynamics protein MID51/0.449
5esoISC2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.449
5kj6NAJAlcohol dehydrogenase E chain1.1.1.10.449
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.448
1eyqNARChalcone--flavonone isomerase 15.5.1.60.448
1me6IVSPlasmepsin-23.4.23.390.448
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.448
1v0pPVBCell division control protein 2 homolog2.7.11.220.448
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.448
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
2p9gNAID-3-phosphoglycerate dehydrogenase1.1.1.950.448
2vcmM11Isopenicillin N synthase1.21.3.10.448
2y60M8FIsopenicillin N synthase1.21.3.10.448
3kozZ97D-ornithine 4,5-aminomutase subunit beta/0.448
3ntaCOAFAD-dependent pyridine nucleotide-disulphide oxidoreductase/0.448
3sufSUEPolyprotein/0.448
3swqEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
3wrmCAMCamphor 5-monooxygenase1.14.15.10.448
4bmvNAPShort-chain dehydrogenase/0.448
4ef8FMNDihydroorotate dehydrogenase (fumarate)/0.448
4fdpFADDecaprenylphosphoryl-beta-D-ribose oxidase/0.448
4ia2BIVVitamin D3 receptor A/0.448
4idgNADPutative UDP-glucose 4-epimerase/0.448
4okb198Androgen receptor/0.448
4rupH97Vitamin D3 receptor A/0.448
1axeNADAlcohol dehydrogenase E chain1.1.1.10.447
1fmjRTLRetinol dehydratase/0.447
1hzjUD1UDP-glucose 4-epimerase/0.447
2e16SAHDiphthine synthase/0.447
2gpjFADSiderophore-interacting protein/0.447
2q59240Peroxisome proliferator-activated receptor gamma/0.447
2vbpVB1Isopenicillin N synthase1.21.3.10.447
2xpvMIYTetracycline repressor protein class D/0.447
2zpaACOtRNA(Met) cytidine acetyltransferase TmcA/0.447
3aezGDPPantothenate kinase2.7.1.330.447
3egvSAHRibosomal protein L11 methyltransferase2.1.10.447
3jvvACPTwitching mobility protein/0.447
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.447
3pe2E1BCasein kinase II subunit alpha2.7.11.10.447
3wv9FEGHmd co-occurring protein HcgE/0.447
4dwvNAJAlcohol dehydrogenase E chain1.1.1.10.447
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.447
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.447
4gkvNADAlcohol dehydrogenase, propanol-preferring1.1.1.10.447
4h4yNAPBiphenyl dioxygenase ferredoxin reductase subunit/0.447
4k9u5AWCytochrome P450 3A4/0.447
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.447
4l9kEHFSerum albumin/0.447
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.447
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.447
5fklTDCTetracycline repressor protein class D/0.447
5jlaNADPutative short-chain dehydrogenase/reductase/0.447
5kcpNAJAlcohol dehydrogenase E chain1.1.1.10.447
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1g4pFQPThiamine-phosphate synthase/0.446
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1t1rIMB1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.446
1tllNAPNitric oxide synthase, brain1.14.13.390.446
2bacFADPutative aminooxidase/0.446
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2trtTACTetracycline repressor protein class D/0.446
2vkvTDCTetracycline repressor protein class D/0.446
2ywwATPAspartate carbamoyltransferase regulatory chain/0.446
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.446
3h86AP5Adenylate kinase/0.446
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
3kpzZNEVitamin D3 receptor/0.446
3ns2PYVAbscisic acid receptor PYL2/0.446
4bfyZVYPantothenate kinase2.7.1.330.446
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.446
4h6pFMNChromate reductase/0.446
4i02CMPcAMP-activated global transcriptional regulator CRP/0.446
4k97ATPCyclic GMP-AMP synthase/0.446
4ohxADPProtein clpf-1/0.446
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.446
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.446
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.446
5fd8A5APutative carboxypeptidase yocD/0.446
5ftcADPTPR domain protein/0.446
1bsvNDPGDP-L-fucose synthase/0.445
1fxsNAPGDP-L-fucose synthase/0.445
1h6cNDPGlucose--fructose oxidoreductase1.1.99.280.445
1hvyD16Thymidylate synthase2.1.1.450.445
1i5bANPChemotaxis protein CheA2.7.13.30.445
1mp0NADAlcohol dehydrogenase class-31.1.1.10.445
2bxfDZPSerum albumin/0.445
2cchATPCyclin-dependent kinase 22.7.11.220.445
2q14ADPPhosphohydrolase/0.445
2y3rTRKTamL/0.445
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.445
3lkiATPFructokinase/0.445
3ls8AJZPhosphatidylinositol 3-kinase catalytic subunit type 32.7.1.1370.445
3ox4NADAlcohol dehydrogenase 21.1.1.10.445
3p74FMNPentaerythritol tetranitrate reductase/0.445
3pdqKC6Lysine-specific demethylase 4A1.14.110.445
3uzwNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
4gu5FADCryptochrome-1/0.445
5fkmTDCTetracycline repressor protein class D/0.445
5fl3ADPPili retraction protein PilT/0.445
5dhhDGWNociceptin receptor/0.445
1drhNAPDihydrofolate reductase1.5.1.30.444
1egdFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.444
1h50FMNPentaerythritol tetranitrate reductase/0.444
1i8tFADUDP-galactopyranose mutase5.4.99.90.444
1nytNAPShikimate dehydrogenase (NADP(+))/0.444
1pdhFASp-hydroxybenzoate hydroxylase/0.444
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.444
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.444
2en5SAHDiphthine synthase/0.444
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
2hrcCHDFerrochelatase, mitochondrial4.99.1.10.444
3ft8MOJHeat shock protein HSP 90-alpha/0.444
3fwgCAMCamphor 5-monooxygenase1.14.15.10.444
3gkiCLRNiemann-Pick C1 protein/0.444
3isjA8DPantothenate synthetase6.3.2.10.444
3lqfNADGalactitol dehydrogenase/0.444
3mnrSD1Heat shock protein HSP 90-alpha/0.444
3mqe416Prostaglandin G/H synthase 21.14.99.10.444
3o153NMThiamine-phosphate synthase/0.444
3q8hAO92-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.444
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.444
3sptUD1Bifunctional protein GlmU/0.444
4bfvZVVPantothenate kinase2.7.1.330.444
4jhz1KVBeta-glucuronidase3.2.1.310.444
4jqh1MFAlr2278 protein/0.444
4prvADPDNA gyrase subunit B/0.444
4rjeFNRLactate oxidase/0.444
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.444
5cb3APRO-acetyl-ADP-ribose deacetylase/0.444
1hetNADAlcohol dehydrogenase E chain1.1.1.10.443
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
1qorNDPQuinone oxidoreductase 1/0.443
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.443
2henADPEphrin type-B receptor 22.7.10.10.443
2hr8SAHDiphthine synthase/0.443
2igoFADPyranose 2-oxidase/0.443
2pk3A2RGDP-6-deoxy-D-mannose reductase/0.443
2vwz7X6Ephrin type-B receptor 42.7.10.10.443
2znoS44Peroxisome proliferator-activated receptor gamma/0.443
3d7kD7KBenzaldehyde lyase/0.443
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3fbuCOAAcetyltransferase, GNAT family/0.443
3p84FMNPentaerythritol tetranitrate reductase/0.443
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.443
3zhsTD6Multifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.443
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.443
4alhA9PBromodomain-containing protein 2/0.443
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.443
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.443
4mihFADPyranose 2-oxidase1.1.3.100.443
4nmdFDABifunctional protein PutA/0.443
12gs0HHGlutathione S-transferase P2.5.1.180.442
1adfTADAlcohol dehydrogenase E chain1.1.1.10.442
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1f3bGBXGlutathione S-transferase A12.5.1.180.442
1ffuFADCarbon monoxide dehydrogenase medium chain/0.442
1m13HYFNuclear receptor subfamily 1 group I member 2/0.442
1mvsDTMDihydrofolate reductase1.5.1.30.442
1tj2FADBifunctional protein PutA1.5.5.20.442
1zg32HIIsoflavone 4'-O-methyltransferase/0.442
2eklNADD-3-phosphoglycerate dehydrogenase/0.442
2gn9UPGUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.442
2ikuLIYRenin3.4.23.150.442
2iyaZIOOleandomycin glycosyltransferase/0.442
3g5hYTTMycocyclosin synthase1.14.21.90.442
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.442
3lu8IQXSerum albumin/0.442
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.442
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.442
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.442
3uovFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.442
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.442
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.442
4dzzADPPlasmid partitioning protein ParF/0.442
4ips1G4Mycocyclosin synthase1.14.21.90.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
4zwgDTPDeoxynucleoside triphosphate triphosphohydrolase SAMHD13.1.50.442
5cdtNAJAlcohol dehydrogenase E chain1.1.1.10.442
5ce3ADPProtein kinase YopO/0.442
1bwsNDPGDP-L-fucose synthase/0.441
1cjuFOKAdenylate cyclase type 2/0.441
1cjuFOKAdenylate cyclase type 5/0.441
1cjvFOKAdenylate cyclase type 2/0.441
1cjvFOKAdenylate cyclase type 5/0.441
1cq8PY6Aspartate aminotransferase2.6.1.10.441
1q43CMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2/0.441
1zz2B11Mitogen-activated protein kinase 14/0.441
2d29FADAcyl-CoA dehydrogenase/0.441
2emuSAHDiphthine synthase/0.441
2jfz003Glutamate racemase/0.441
2pamTYDTDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase5.3.2.30.441
2vx07X7Ephrin type-B receptor 42.7.10.10.441
2vx17X8Ephrin type-B receptor 42.7.10.10.441
2y6fM9FIsopenicillin N synthase1.21.3.10.441
2ylrNAPPhenylacetone monooxygenase1.14.13.920.441
2zdu446Mitogen-activated protein kinase 102.7.11.240.441
3c1y2BADNA integrity scanning protein DisA/0.441
3e8xNAPBH1520 protein/0.441
3eem53VUncharacterized protein/0.441
3ibqATPPyridoxal kinase/0.441
3icrFADCoenzyme A disulfide reductase/0.441
3n0cFADFlavin-dependent thymidylate synthase2.1.1.1480.441
3oquA8SAbscisic acid receptor PYL9/0.441
3sdkP3NProteasome subunit beta type-53.4.25.10.441
3sdkP3NProteasome subunit beta type-63.4.25.10.441
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.441
3tx1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.441
3w0pADPHygromycin-B 4-O-kinase2.7.1.1630.441
4a5lNDPThioredoxin reductase/0.441
4a61ANPPlasmid segregation protein ParM/0.441
4bgg844Activin receptor type-12.7.11.300.441
4dieC5PCytidylate kinase/0.441
4fv7E94Mitogen-activated protein kinase 12.7.11.240.441
4jxrACOAcetyltransferase/0.441
4ohwATPProtein clpf-1/0.441
4tmcFMNOld yellow enzyme/0.441
4xw4ANPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
5eoxADPType 4 fimbrial biogenesis protein PilM/0.441
5kjeNAJAlcohol dehydrogenase E chain1.1.1.10.441
1a9yUPGUDP-glucose 4-epimerase5.1.3.20.440
1cf3FADGlucose oxidase1.1.3.40.440
1dyjDDFDihydrofolate reductase1.5.1.30.440
1k6tXN1Gag-Pol polyprotein3.4.23.160.440
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.440
1nahNADUDP-glucose 4-epimerase5.1.3.20.440
1upw444Oxysterols receptor LXR-beta/0.440
1wlvCOAPhenylacetic acid degradation protein PaaI/0.440
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.440
2bueCOAAAC(6')-Ib/0.440
2e77FMNLactate oxidase/0.440
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.440
2olrATPPhosphoenolpyruvate carboxykinase (ATP)/0.440
2parTMP5'-deoxynucleotidase YfbR/0.440
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.440
2xj2985Serine/threonine-protein kinase pim-12.7.11.10.440
2xlrFADPutative flavin-containing monooxygenase/0.440
2xlsNAPPutative flavin-containing monooxygenase/0.440
2zs8ADPPantothenate kinase2.7.1.330.440
3crlANP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.440
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.440
3u4cNDPNADPH-dependent reductase BacG/0.440
4bl5GFBGDP-L-fucose synthase1.1.1.2710.440
4ng5NAJAlcohol dehydrogenase E chain1.1.1.10.440
4o71CPBBromodomain-containing protein 4/0.440
4r8hSP1cAMP-activated global transcriptional regulator CRP/0.440
4u0oMTALipoyl synthase 2/0.440
5cwa0GAAnthranilate synthase component 14.1.3.270.440
5eccNAPDehydrofolate reductase type I/0.440