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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3l04SN0N-acetylornithine carbamoyltransferase2.1.3.9

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
3l04SN0N-acetylornithine carbamoyltransferase2.1.3.91.000
3kzoAN0N-acetylornithine carbamoyltransferase2.1.3.90.817
3l06SN0N-acetylornithine carbamoyltransferase2.1.3.90.756
3l05SN0N-acetylornithine carbamoyltransferase2.1.3.90.649
3m4nPA9N-acetylornithine carbamoyltransferase2.1.3.90.595
2bf7HBIPteridine reductase 11.5.1.330.504
3ba6AN2Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.501
4lb2DM5Serum albumin/0.500
1pr4MTPPurine nucleoside phosphorylase DeoD-type/0.497
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.495
1w1wAGSStructural maintenance of chromosomes protein 1/0.493
4ddrMMVDihydrofolate reductase1.5.1.30.492
1jcm137Tryptophan biosynthesis protein TrpCF4.1.1.480.490
4b4w9L9Bifunctional protein FolD/0.490
1lkeDOGBilin-binding protein/0.487
3vf60H6Glucokinase2.7.1.20.487
4xnhACON-terminal acetyltransferase A complex subunit NAT52.3.10.487
1h60STRPentaerythritol tetranitrate reductase/0.484
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.484
3s41S41Glucokinase2.7.1.20.482
1bcpATPPertussis toxin subunit 4/0.481
1bcpATPPertussis toxin subunit 5/0.481
3w6uNAP6-phosphogluconate dehydrogenase, NAD-binding protein/0.481
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.481
3dgeADPSensor histidine kinase/0.480
3lfzADPUncharacterized protein MJ1225/0.480
4ea2RWZDehydrosqualene synthase/0.480
4h9tHL4Phosphotriesterase/0.480
4i1nFOLDihydrofolate reductase1.5.1.30.480
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.479
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.479
3zkyWT4Isopenicillin N synthase1.21.3.10.479
3gncQQQGlutaryl-CoA dehydrogenase/0.478
4fa30SLAldo-keto reductase family 1 member C3/0.478
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.477
3h4vDVPPteridine reductase 11.5.1.330.477
3mjrAC2Deoxycytidine kinase2.7.1.740.477
1je1GMPPurine nucleoside phosphorylase/0.476
1mvtDTMDihydrofolate reductase1.5.1.30.476
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.476
1vbiNADMalate/L-lactate dehydrogenase family protein/0.476
3dntATPSerine/threonine-protein kinase toxin HipA/0.476
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.476
3sl2ATPSensor histidine kinase WalK/0.476
1ejbINJ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.475
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.475
2xkeWI2Serine/threonine-protein kinase Nek22.7.11.10.475
3njoPYVAbscisic acid receptor PYR1/0.475
4fj0HHF17beta-hydroxysteroid dehydrogenase/0.475
1uaeUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.474
2g78REACellular retinoic acid-binding protein 2/0.474
2z4sADPChromosomal replication initiator protein DnaA/0.474
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.474
4bewACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.474
4gki0JNAminoglycoside 3'-phosphotransferase AphA1-IAB/0.474
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.474
4lxjLANLanosterol 14-alpha demethylase1.14.13.700.474
2y60M8FIsopenicillin N synthase1.21.3.10.473
4bqpNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.473
4cthRDFNeprilysin/0.473
4pzsACOHistone acetyltransferase p300/0.473
1cq7PY5Aspartate aminotransferase2.6.1.10.472
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.472
3a0iAJIGlucokinase2.7.1.20.472
4bb3KKAIsopenicillin N synthase1.21.3.10.472
4bfzZVZPantothenate kinase2.7.1.330.472
1d3pBT3Prothrombin3.4.21.50.471
2a9z26AAdenosine kinase2.7.1.200.471
2x7hPFNProstaglandin reductase 310.471
2xtnGTPGTPase IMAP family member 2/0.471
2zb8IMNProstaglandin reductase 21.3.1.480.471
3acw651Dehydrosqualene synthase/0.471
3eigMTXDihydrofolate reductase1.5.1.30.471
4a6rTA8Probable aminotransferase/0.471
5stdUNNScytalone dehydratase4.2.1.940.471
1nquRDL6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.470
2rkuR78Serine/threonine-protein kinase PLK12.7.11.210.470
4j521J3Serine/threonine-protein kinase PLK12.7.11.210.470
1mxfMTXPutative pteridine reductase 2/0.469
1r8qAFBCytohesin-2/0.469
1r8qAFBADP-ribosylation factor 1/0.469
1w7h3IPMitogen-activated protein kinase 14/0.469
1ygjRMCPyridoxal kinase2.7.1.350.469
2bfmTOPPteridine reductase 11.5.1.330.469
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.469
3akm11DFatty acid-binding protein, intestinal/0.469
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.469
3wagTYDGlycosyltransferase/0.469
4jxxATPGlutamine--tRNA ligase6.1.1.180.469
1oc1ASVIsopenicillin N synthase1.21.3.10.468
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.468
4b4vL34Bifunctional protein FolD/0.468
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.468
4u07ATPAdenosine monophosphate-protein transferase FICD2.7.7.n10.468
1culFOKAdenylate cyclase type 2/0.467
1culFOKAdenylate cyclase type 5/0.467
1obnASVIsopenicillin N synthase1.21.3.10.467
1w06W05Isopenicillin N synthase1.21.3.10.467
2bfaCB3Pteridine reductase 11.5.1.330.467
2r0cFADPutative FAD-monooxygenase/0.467
2wo7ASVIsopenicillin N synthase1.21.3.10.467
2xkfBX1Serine/threonine-protein kinase Nek22.7.11.10.467
2y6fM9FIsopenicillin N synthase1.21.3.10.467
3zg6APRNAD-dependent protein deacetylase sirtuin-63.5.10.467
1ihiIU5Aldo-keto reductase family 1 member C2/0.466
1uzwCDHIsopenicillin N synthase1.21.3.10.466
3c35KAIGlutamate receptor ionotropic, kainate 1/0.466
3zoiM2WIsopenicillin N synthase1.21.3.10.466
3zsh469Mitogen-activated protein kinase 14/0.466
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
4f6vZYMDehydrosqualene synthase/0.466
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.466
5ckwANPUncharacterized protein/0.466
5d7oAR6NAD-dependent protein deacetylase sirtuin-23.5.10.466
1mvsDTMDihydrofolate reductase1.5.1.30.465
1rd4L08Integrin alpha-L/0.465
1u1f183Uridine phosphorylase2.4.2.30.465
1xddAAYIntegrin alpha-L/0.465
2othNIMBasic phospholipase A2 VRV-PL-VIIIa3.1.1.40.465
3epsATPIsocitrate dehydrogenase kinase/phosphatase/0.465
3hl0NADMaleylacetate reductase/0.465
4g8jTHMUridine phosphorylase/0.465
4iarERM5-hydroxytryptamine receptor 1B/0.465
4lngJANCaaX farnesyltransferase beta subunit Ram1/0.465
1fduNAPEstradiol 17-beta-dehydrogenase 11.1.1.620.464
1ry0PG2Aldo-keto reductase family 1 member C3/0.464
2abaSTRPentaerythritol tetranitrate reductase/0.464
3cqeP91Wee1-like protein kinase2.7.10.20.464
3d5wADPSerine/threonine-protein kinase PLK/0.464
3da24MDCarbonic anhydrase 134.2.1.10.464
3fnfJPMEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
3tlc7MDMicrocin C7 self-immunity protein MccF/0.464
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.464
1ivrCBAAspartate aminotransferase, mitochondrial2.6.1.10.463
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.463
1stdBFSScytalone dehydratase4.2.1.940.463
1wpgADPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.463
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.463
3fhxPXLPyridoxal kinase2.7.1.350.463
4a2aATPCell division protein FtsA/0.463
4tx9AMZPhosphoribosyl isomerase A/0.463
1jcq739Protein farnesyltransferase subunit beta2.5.1.580.462
3eej53RUncharacterized protein/0.462
3hu2AGSTransitional endoplasmic reticulum ATPase3.6.4.60.462
3qm4PN0Cytochrome P450 2D6/0.462
3emlZMAAdenosine receptor A2a/0.462
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.461
1e2lTMCThymidine kinase/0.461
1n95HFPProtein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.461
1n95HFPProtein farnesyltransferase subunit beta2.5.1.580.461
1yw9A84Methionine aminopeptidase 2/0.461
2iyaZIOOleandomycin glycosyltransferase/0.461
2x9vTMQPteridine reductase/0.461
3bgxTMPThymidylate synthase/0.461
3qlxQLRUncharacterized protein/0.461
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.461
4eilUMPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.461
4pt0NADAldehyde dehydrogenase/0.461
1bk0ACVIsopenicillin N synthase1.21.3.10.460
1e92HBIPteridine reductase 11.5.1.330.460
1puaCOAHAT A1/0.460
1q0zAKAAclacinomycin methylesterase RdmC3.1.1.950.460
1x2hLPALipoate-protein ligase A6.3.1.200.460
2e94364Geranylgeranyl pyrophosphate synthase/0.460
2rd2QSIGlutamine--tRNA ligase6.1.1.180.460
2vatCOAAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.460
3elePLPAminotransferase/0.460
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.460
3qe2FMNNADPH--cytochrome P450 reductase/0.460
3v0p4GWHisto-blood group ABO system transferase/0.460
4c49HCYCorticosteroid-binding globulin/0.460
4rvgTYDD-mycarose 3-C-methyltransferase/0.460
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.460
4xzjNADPutative NAD(+)--arginine ADP-ribosyltransferase Vis2.4.2.310.460
1k4gAIQQueuine tRNA-ribosyltransferase2.4.2.290.459
1ot3THMDeoxynucleoside kinase/0.459
1zg32HIIsoflavone 4'-O-methyltransferase/0.459
2hveADPNucleoside diphosphate kinase A2.7.4.60.459
3b04OOPIsopentenyl-diphosphate delta-isomerase/0.459
3e33ED7Protein farnesyltransferase subunit beta2.5.1.580.459
3fe1ADPHeat shock 70 kDa protein 6/0.459
3fgoACPSarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.459
3juqAKDPhenazine biosynthesis protein A/B/0.459
3q1kADPD-alanine--D-alanine ligase A6.3.2.40.459
3vi7CBDHematopoietic prostaglandin D synthase/0.459
4a81DXCMajor pollen allergen Bet v 1-A/0.459
4fj1GEN17beta-hydroxysteroid dehydrogenase/0.459
4jyzATPGlutamine--tRNA ligase6.1.1.180.459
4kodADPTransitional endoplasmic reticulum ATPase3.6.4.60.459
4l17DNQGlutamate receptor 2/0.459
4wfr2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.459
1h61PDNPentaerythritol tetranitrate reductase/0.458
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.458
1n4pCYS_VAL_ILE_LEU_GERGeranylgeranyl transferase type-1 subunit beta2.5.1.590.458
1o6rR19Squalene--hopene cyclase4.2.1.1290.458
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
1xmmM7Gm7GpppX diphosphatase3.6.1.590.458
1z4iUMP5'(3')-deoxyribonucleotidase, mitochondrial3.1.30.458
2cjeDUNDUTPase/0.458
2getCOKPantothenate kinase2.7.1.330.458
2qw034Z4-chlorobenzoyl CoA ligase/0.458
3ekuCY9Actin-5C/0.458
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.458
3zecANPAdenosine monophosphate-protein transferase SoFic2.7.7.n10.458
4a4xJUPSerine/threonine-protein kinase Nek22.7.11.10.458
4f0e0RUPoly [ADP-ribose] polymerase 152.4.2.300.458
4lzwTHMUridine phosphorylase/0.458
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.457
1icvFMNOxygen-insensitive NAD(P)H nitroreductase/0.457
1kh3ANPArgininosuccinate synthase/0.457
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.457
3c6n2S8Protein TRANSPORT INHIBITOR RESPONSE 1/0.457
3lfm3DTAlpha-ketoglutarate-dependent dioxygenase FTO/0.457
3x04GNPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.457
4i13FOLDihydrofolate reductase1.5.1.30.457
5jtbZMAAdenosine receptor A2a/0.457
1enoNADEnoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic1.3.1.90.456
1jdzFMBPurine nucleoside phosphorylase/0.456
1p0pBCHCholinesterase3.1.1.80.456
1pqc444Oxysterols receptor LXR-beta/0.456
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.456
2bsxNOSPurine nucleoside phosphorylase/0.456
2jb4A14Isopenicillin N synthase1.21.3.10.456
3burTES3-oxo-5-beta-steroid 4-dehydrogenase/0.456
3hf6LX0Tryptophan 5-hydroxylase 11.14.16.40.456
3pdtADPMyosin heavy chain kinase A2.7.11.70.456
3vweCOAAlpha-tubulin N-acetyltransferase 1/0.456
4ea0651Dehydrosqualene synthase/0.456
4gh30EVQueuine tRNA-ribosyltransferase2.4.2.290.456
1thnADPAnti-sigma F factor/0.455
1z4uPH9Polyprotein/0.455
2w6oOA3Biotin carboxylase6.3.4.140.455
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.455
3fznD7KBenzoylformate decarboxylase4.1.1.70.455
3h3t16HCollagen type IV alpha-3-binding protein/0.455
3kwn23ZCathepsin S3.4.22.270.455
3o76GTBGlutathione S-transferase P 12.5.1.180.455
3tfp03LDehydrosqualene synthase/0.455
4bixADPSensor histidine kinase CpxA/0.455
4ffrATPUncharacterized protein/0.455
4g7gVFVLanosterol 14-alpha-demethylase/0.455
4gkh0J9Aminoglycoside 3'-phosphotransferase AphA1-IAB/0.455
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.455
5f54TMPSingle-stranded-DNA-specific exonuclease/0.455
3qakUKAAdenosine receptor A2a/0.455
1blzACVIsopenicillin N synthase1.21.3.10.454
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.454
1hfpMOTDihydrofolate reductase1.5.1.30.454
1hfqMOTDihydrofolate reductase1.5.1.30.454
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.454
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.454
2acwUPGGlycosyltransferase/0.454
2bfpH4BPteridine reductase 11.5.1.330.454
2cftPLPPyridoxal phosphate phosphatase/0.454
3e32ED2Protein farnesyltransferase subunit beta2.5.1.580.454
3qj5022Alcohol dehydrogenase class-31.1.1.10.454
4gh10WXQueuine tRNA-ribosyltransferase2.4.2.290.454
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.454
1cjkFOKAdenylate cyclase type 2/0.453
1cjkFOKAdenylate cyclase type 5/0.453
1cqp803Integrin alpha-L/0.453
1u2gAPRNAD(P) transhydrogenase subunit alpha part 11.6.1.20.453
2jh0701Prothrombin3.4.21.50.453
2o6hINI6,7-dimethyl-8-ribityllumazine synthase 12.5.1.780.453
2ovvPFHcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.453
2xlsFADPutative flavin-containing monooxygenase/0.453
3cgyRDCVirulence sensor histidine kinase PhoQ2.7.13.30.453
3hu1AGSTransitional endoplasmic reticulum ATPase3.6.4.60.453
3keqNADRedox-sensing transcriptional repressor Rex/0.453
3sqwANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.453
4qbiAP5Adenylate kinase/0.453
5d7qAR6NAD-dependent protein deacetylase sirtuin-23.5.10.453
1bzfTMQDihydrofolate reductase1.5.1.30.452
1n95FTHProtein farnesyltransferase subunit beta2.5.1.580.452
1nsyATPNH(3)-dependent NAD(+) synthetase6.3.1.50.452
1vkgCRIHistone deacetylase 83.5.1.980.452
1zw9H64ATP-dependent molecular chaperone HSP82/0.452
2abjCBCBranched-chain-amino-acid aminotransferase, cytosolic2.6.1.420.452
2od7A1RNAD-dependent protein deacetylase HST23.5.10.452
2wpwACOOrf14/0.452
2ydbNAP2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.452
3nxyD2HDihydrofolate reductase1.5.1.30.452
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.452
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.452
4hs4FMNChromate reductase/0.452
4jq3ZOMAldo-keto reductase family 1 member C2/0.452
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.452
4omaLCSMethionine gamma-lyase/0.452
4p9dTMPDeoxycytidylate deaminase/0.452
4rh10TTSpore photoproduct lyase/0.452
5ez4NADBetaine-aldehyde dehydrogenase/0.452
5iu4ZMAAdenosine receptor A2a/0.452
1axwMTXThymidylate synthase/0.451
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
1x1aSAMC-20 methyltransferase/0.451
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.451
2ejzSAHDiphthine synthase/0.451
3bi6396Wee1-like protein kinase2.7.10.20.451
3hpqAP5Adenylate kinase/0.451
3qly55VUncharacterized protein/0.451
3ukfGDUUDP-galactopyranose mutase/0.451
3zeiAWHO-acetylserine sulfhydrylase/0.451
4bgbADPPredicted molecular chaperone distantly related to HSP70-fold metalloproteases/0.451
1ankANPAdenylate kinase/0.450
1sa5BMVProtein farnesyltransferase subunit beta2.5.1.580.450
1t4cCOAFormyl-CoA:oxalate CoA-transferase/0.450
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2b0qADPAminoglycoside 3'-phosphotransferase2.7.1.950.450
2cn0F25Prothrombin3.4.21.50.450
2ea4F79Methionine aminopeptidase 2/0.450
2vcmM11Isopenicillin N synthase1.21.3.10.450
2w3aTOPDihydrofolate reductase1.5.1.30.450
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3c14FOKAdenylate cyclase type 2/0.450
3c14FOKAdenylate cyclase type 5/0.450
3fp0FP015-O-acetyltransferase/0.450
3hdyGDUUDP-galactopyranose mutase/0.450
3hziATPSerine/threonine-protein kinase toxin HipA/0.450
3iej599Cathepsin S3.4.22.270.450
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3px3T3QdTDP-3-amino-3,6-dideoxy-alpha-D-glucopyranose N,N-dimethyltransferase2.1.1.2350.450
3sfy3FYUncharacterized protein/0.450
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
3sqzCOAPutative hydroxymethylglutaryl-CoA synthase/0.450
4bhw01KHistone acetyltransferase p300/0.450
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.450
4fh5UTPTerminal uridylyltransferase cid1/0.450
4fhd0TTSpore photoproduct lyase/0.450
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.450
4jlm1NNDeoxycytidine kinase2.7.1.740.450
4jq4IMNAldo-keto reductase family 1 member C2/0.450
4pkwGM6Lethal factor3.4.24.830.450
4wdfA2P2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.450
5dozNDPJamJ/0.450
5dhgDGVNociceptin receptor/0.450
1gesFADGlutathione reductase1.8.1.70.449
1qiqACCIsopenicillin N synthase1.21.3.10.449
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
2b1z17MEstrogen receptor/0.449
2bryFAD[F-actin]-methionine sulfoxide oxidase MICAL11.14.130.449
2fonFADAcyl-coenzyme A oxidase/0.449
2jizANPATP synthase subunit beta, mitochondrial3.6.3.140.449
2puiADPMethylthioribose kinase2.7.1.1000.449
2xk4OL2Serine/threonine-protein kinase Nek22.7.11.10.449
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.449
3b9lAZZSerum albumin/0.449
3pz23PZGeranylgeranyl transferase type-2 subunit beta2.5.1.600.449
3q7fED2Uncharacterized protein/0.449
3qwiCUE17beta-hydroxysteroid dehydrogenase/0.449
3vcyUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.449
3wrmCAMCamphor 5-monooxygenase1.14.15.10.449
4ap1NAPSteroid monooxygenase/0.449
4b13X25Glycylpeptide N-tetradecanoyltransferase/0.449
4k39SAMAnaerobic sulfatase-maturating enzyme1.8.980.449
4u7wNDPMxaA/0.449
1d6w00RProthrombin3.4.21.50.448
1h36R88Squalene--hopene cyclase4.2.1.1290.448
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.448
1kl2FONSerine hydroxymethyltransferase/0.448
1sl9CZHObelin/0.448
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.448
2gouFMNNADH:flavin oxidoreductase Sye1/0.448
2ij7TPFMycocyclosin synthase1.14.21.90.448
2o7pNAPRiboflavin biosynthesis protein RibD/0.448
2zcqB65Dehydrosqualene synthase/0.448
2zhe13UProthrombin3.4.21.50.448
3zdfNADGlyceraldehyde-3-phosphate dehydrogenase/0.448
4c3yANB3-ketosteroid dehydrogenase/0.448
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.448
4dyp0MSNucleoprotein/0.448
4pzrCOAHistone acetyltransferase p300/0.448
1a9cGTPGTP cyclohydrolase 13.5.4.160.447
1db56INPhospholipase A2, membrane associated/0.447
1dr4HBIDihydrofolate reductase1.5.1.30.447
1e2nRCAThymidine kinase/0.447
1euyQSIGlutamine--tRNA ligase6.1.1.180.447
1hb1OCVIsopenicillin N synthase1.21.3.10.447
1hb3SCVIsopenicillin N synthase1.21.3.10.447
1iahADPTransient receptor potential cation channel subfamily M member 72.7.11.10.447
1kquBR4Phospholipase A2, membrane associated/0.447
1qjfACSIsopenicillin N synthase1.21.3.10.447
1u1cBAUUridine phosphorylase2.4.2.30.447
1wxjIPLTryptophan synthase alpha chain/0.447
1ypeUIPProthrombin3.4.21.50.447
1yqj6NPMitogen-activated protein kinase 14/0.447
2fjaFADAdenylylsulfate reductase, subunit A (AprA)/0.447
2g1n1IGRenin3.4.23.150.447
2wnbC5PCMP-N-acetylneuraminate-beta-galactosamide-alpha-2,3-sialyltransferase 12.4.99.40.447
3eon341Glutaryl-CoA dehydrogenase/0.447
3h3r14HCollagen type IV alpha-3-binding protein/0.447
3p9tTCLRepressor/0.447
4i421HA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.447
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.447
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.447
5c4fUPGHisto-blood group ABO system transferase/0.447
1fmjRTLRetinol dehydratase/0.446
1ia4TQ6Dihydrofolate reductase1.5.1.30.446
1odjGMPPurine nucleoside phosphorylase/0.446
1oytFSNProthrombin3.4.21.50.446
1rxjBNIStreptavidin/0.446
1u1d181Uridine phosphorylase2.4.2.30.446
1upw444Oxysterols receptor LXR-beta/0.446
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1ychFMNNitric oxide reductase10.446
2qc8ADPGlutamine synthetase6.3.1.20.446
2yhuWHFPteridine reductase/0.446
2z7gEH9Adenosine deaminase3.5.4.40.446
3e6eDCSAlanine racemase/0.446
3e6yCW114-3-3-like protein C/0.446
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.446
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.446
3jqgAX6Pteridine reductase, putative/0.446
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.446
3lnbCOAN-acetyltransferase family protein/0.446
3p0fBAUUridine phosphorylase 22.4.2.30.446
3phjDHKShikimate dehydrogenase (NADP(+))/0.446
3stdMQ0Scytalone dehydratase4.2.1.940.446
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.446
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.446
3vnhFUUKelch-like ECH-associated protein 1/0.446
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.446
4boeCLRJapanin/0.446
4d6qPD2Lysine-specific demethylase 4D1.14.110.446
4dc0NDPPutative ketoacyl reductase1.3.10.446
4fgrADPPhosphoribosylaminoimidazole-succinocarboxamide synthase6.3.2.60.446
4nieNBHNuclear receptor ROR-gamma/0.446
4u0k744Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
4yx6FMNOmega-3 polyunsaturated fatty acid synthase subunit PfaD/0.446
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.446
1b2lNDCAlcohol dehydrogenase1.1.1.10.445
1fx9MJIPhospholipase A2, major isoenzyme3.1.1.40.445
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.445
1uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.445
1uhlMEIRetinoic acid receptor RXR-beta/0.445
1x1rGDPRas-related protein M-Ras/0.445
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
2g44T3OEstrogen receptor/0.445
2vczVC3Hematopoietic prostaglandin D synthase/0.445
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.445
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.445
3pcnDHYProtocatechuate 3,4-dioxygenase alpha chain1.13.11.30.445
3pcnDHYProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.445
3r8hZOMAldo-keto reductase family 1 member C3/0.445
3tptADPSerine/threonine-protein kinase toxin HipA/0.445
3vx4ATPPutative ABC transporter, ATP-binding protein ComA/0.445
3w1wCHDFerrochelatase, mitochondrial4.99.1.10.445
3ziaADPATP synthase subunit beta, mitochondrial3.6.3.140.445
3zv64HBCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.445
4ej1FOLDihydrofolate reductase1.5.1.30.445
4hfp15UProthrombin3.4.21.50.445
4oe4NADDelta-1-pyrroline-5-carboxylate dehydrogenase, mitochondrial1.2.1.880.445
4xz3COAAcyl-CoA synthetase (NDP forming)/0.445
4yal2AMNADPH--cytochrome P450 reductase/0.445
5ej4TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.445
4mqt2CUMuscarinic acetylcholine receptor M2/0.445
1qrtATPGlutamine--tRNA ligase6.1.1.180.444
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
1towCRZFatty acid-binding protein, adipocyte/0.444
1ygkRRCPyridoxal kinase2.7.1.350.444
2fzjDH3Dihydrofolate reductase1.5.1.30.444
2r2mI50Prothrombin3.4.21.50.444
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
2vaxCSCAcetyl-CoA--deacetylcephalosporin C acetyltransferase2.3.1.1750.444
2xtbKRMAdenosine kinase, putative/0.444
2y71CB63-dehydroquinate dehydratase4.2.1.100.444
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.444
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.444
3rtmRTMBeta-secretase 13.4.23.460.444
3tfuPL8Adenosylmethionine-8-amino-7-oxononanoate aminotransferase2.6.1.620.444
3x0a5GPPhosphatidylinositol 5-phosphate 4-kinase type-2 beta2.7.1.1490.444
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4ez8DHFThymidylate synthase2.1.1.450.444
4g2gTDHMycocyclosin synthase1.14.21.90.444
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4xba5GPAprataxin-like protein30.444
5dibNADBetaine-aldehyde dehydrogenase/0.444
1dghNDPCatalase1.11.1.60.443
1f3bGBXGlutathione S-transferase A12.5.1.180.443
1opbRETRetinol-binding protein 2/0.443
1rftPXMPyridoxal kinase2.7.1.350.443
1tlcF89Thymidylate synthase/0.443
1u1gBBBUridine phosphorylase2.4.2.30.443
1w19T1P6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.443
1z5uCMPClass B acid phosphatase/0.443
2ea2F77Methionine aminopeptidase 2/0.443
2ev9NAPShikimate dehydrogenase (NADP(+))/0.443
2glxNDP1,5-anhydro-D-fructose reductase/0.443
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2pupADPMethylthioribose kinase2.7.1.1000.443
2vbdV10Isopenicillin N synthase1.21.3.10.443
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.443
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3ebiBEYM1 family aminopeptidase3.4.110.443
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.443
3tfyCOAN-alpha-acetyltransferase 502.3.10.443
3x21FMNOxygen-insensitive NAD(P)H nitroreductase/0.443
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.443
4bfsZVSPantothenate kinase2.7.1.330.443
4dlcUMPDeoxyuridine triphosphatase, putative/0.443
4f6xZYLDehydrosqualene synthase/0.443
4fex0TOAminoglycoside 3'-phosphotransferase AphA1-IAB/0.443
4nv0MG77-methylguanosine phosphate-specific 5'-nucleotidase/0.443
4pnmNU1Tankyrase-22.4.2.300.443
5jscFADPutative acyl-CoA dehydrogenase/0.443
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.442
1h66RH1NAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1jraFADFAD-linked sulfhydryl oxidase ERV21.8.3.20.442
1n2vBDIQueuine tRNA-ribosyltransferase2.4.2.290.442
1ni1HFPProtein farnesyltransferase subunit beta2.5.1.580.442
1r5gAO1Methionine aminopeptidase 2/0.442
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.442
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.442
2feuCAMCamphor 5-monooxygenase1.14.15.10.442
2flhZEACytokinin-specific binding protein/0.442
2gevCOKPantothenate kinase2.7.1.330.442
2hpsCTZCa2+-triggered coelenterazine-binding protein 1/0.442
2p4iMR9Angiopoietin-1 receptor2.7.10.10.442
2pbzATPUncharacterized protein/0.442
2yp0OVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.442
2zrxFMNIsopentenyl-diphosphate delta-isomerase/0.442
3dejRXCCaspase-33.4.22.560.442
3gwfNAPCyclohexanone monooxygenase/0.442
3h3qH13Collagen type IV alpha-3-binding protein/0.442
3nxtD2EDihydrofolate reductase1.5.1.30.442
3ogkOGKCoronatine-insensitive protein 1/0.442
3ojgHL4Phosphotriesterase/0.442
3q9bB3NAcetylpolyamine amidohydrolase/0.442
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.442
3t3r9PLCytochrome P450 2A61.14.130.442
3up3XCAaceDAF-12/0.442
4dhyS41Glucokinase2.7.1.20.442
4e0u0MVCyclic dipeptide N-prenyltransferase/0.442
4fhf0TTSpore photoproduct lyase/0.442
4fxfATPPyruvate kinase PKM2.7.1.400.442
4gt8ADPSensor protein VraS2.7.13.30.442
4kebFOLDihydrofolate reductase1.5.1.30.442
4ktl1CQCytochrome P450/0.442
4q15HFGProline--tRNA ligase6.1.1.150.442
4yau2AMNADPH--cytochrome P450 reductase/0.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5dp2NAPCurF/0.442
5k2aZMAAdenosine receptor A2a/0.442
5iua6DXAdenosine receptor A2a/0.442
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
1disBDMDihydrofolate reductase1.5.1.30.441
1dqaCOA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
1kyxCRM6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.441
1n83CLRNuclear receptor ROR-alpha/0.441
1necFMNOxygen-insensitive NAD(P)H nitroreductase10.441
1ra3NAPDihydrofolate reductase1.5.1.30.441
1txtCAAHMG-CoA synthase/0.441
1u0hONMAdenylate cyclase type 2/0.441
1u0hONMAdenylate cyclase type 5/0.441
1xoqROFcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
2io9ADPBifunctional glutathionylspermidine synthetase/amidase/0.441
2lfoGCHFatty acid-binding protein, liver/0.441
2wowNDPTrypanothione reductase/0.441
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.441
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.441
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.441
3fr28CAFatty acid-binding protein, adipocyte/0.441
3h2sNDPPutative NADH-flavin reductase/0.441
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.441
3rgaILDEpoxide hydrolase LasB5.5.10.441
3tdaPN0Cytochrome P450 2D6/0.441
3tfn2CJDehydrosqualene synthase/0.441
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.441
4a4l939Serine/threonine-protein kinase PLK12.7.11.210.441
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.441
4hl1ZZ7Metallo-beta-lactamase type 2/0.441
4ixd1HVIntegrin alpha-L/0.441
4jqh1MFAlr2278 protein/0.441
4nwiCTN7-methylguanosine phosphate-specific 5'-nucleotidase/0.441
4tyqAP5Adenylate kinase/0.441
4u0oMTALipoyl synthase 2/0.441
4xmxBESAminopeptidase N3.4.11.20.441
1nhkCMPNucleoside diphosphate kinase2.7.4.60.440
1o6qR17Squalene--hopene cyclase4.2.1.1290.440
1p33MTXPteridine reductase 11.5.1.330.440
1ra2FOLDihydrofolate reductase1.5.1.30.440
1rzuADPGlycogen synthase 12.4.1.210.440
1thz326Bifunctional purine biosynthesis protein PURH2.1.2.30.440
1vf2GTXGlutathione S-transferase 32.5.1.180.440
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.440
2b4yAPRNAD-dependent protein deacylase sirtuin-5, mitochondrial/0.440
2bu9HFVIsopenicillin N synthase1.21.3.10.440
2dvlFADAcyl-CoA dehydrogenase/0.440
2geuCOKPantothenate kinase2.7.1.330.440
2gjnFMNNitronate monooxygenase1.13.12.160.440
2h6iCYS_VAL_LEU_SER_GERProtein farnesyltransferase subunit beta2.5.1.580.440
2oyeIM8Prostaglandin G/H synthase 11.14.99.10.440
2rqfJH3Hemolymph juvenile hormone binding protein/0.440
2xkc4VQSerine/threonine-protein kinase Nek22.7.11.10.440
3arvSAUChitinase A/0.440
3bl7DD1m7GpppX diphosphatase3.6.1.590.440
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.440
3fwgCAMCamphor 5-monooxygenase1.14.15.10.440
3h3sH15Collagen type IV alpha-3-binding protein/0.440
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.440
3maaFKPAdenylate cyclase type 2/0.440
3maaFKPAdenylate cyclase type 5/0.440
3tl1JROPutative polyketide cyclase/0.440
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
4ax9N5NProthrombin3.4.21.50.440
4bfuZVUPantothenate kinase2.7.1.330.440
4djx0KQBeta-secretase 13.4.23.460.440
4eb4UMPThymidylate synthase2.1.1.450.440
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.440
4fflADPUncharacterized protein/0.440
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.440
4kq6DLZ6,7-dimethyl-8-ribityllumazine synthase/0.440
4ktkKTKCytochrome P450/0.440
4zhiADPKinesin-like protein KIF11/0.440
5ab7MLCNonspecific lipid-transfer protein, putative/0.440
3pblETQD(3) dopamine receptor/0.440