sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2fyp | RDE | Endoplasmin |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2fyp | RDE | Endoplasmin | / | 1.000 | |
| 2hch | N5A | Endoplasmin | / | 0.655 | |
| 2gqp | PA7 | Endoplasmin | / | 0.627 | |
| 4fcr | 0TM | Heat shock protein HSP 90-alpha | / | 0.624 | |
| 3rlq | 3RQ | Heat shock protein HSP 90-alpha | / | 0.617 | |
| 1u0z | RDC | Endoplasmin | / | 0.613 | |
| 2gfd | RDA | Endoplasmin | / | 0.608 | |
| 1ysz | NEC | Endoplasmin | / | 0.599 | |
| 3t10 | ACP | Heat shock protein HSP 90-alpha | / | 0.596 | |
| 3ekr | PY9 | Heat shock protein HSP 90-alpha | / | 0.594 | |
| 2hg1 | N5O | Endoplasmin | / | 0.590 | |
| 1qy8 | RDI | Endoplasmin | / | 0.587 | |
| 2yef | ANP | Heat shock protein HSP 90-alpha | / | 0.587 | |
| 2yeg | XQG | Heat shock protein HSP 90-alpha | / | 0.587 | |
| 1u2o | NEC | Endoplasmin | / | 0.584 | |
| 2exl | GDM | Endoplasmin | / | 0.582 | |
| 2xx2 | 13C | ATP-dependent molecular chaperone HSP82 | / | 0.581 | |
| 4bqj | XKL | Heat shock protein HSP 90-alpha | / | 0.579 | |
| 4ipe | ANP | TNF receptor-associated protein 1 | / | 0.578 | |
| 2fxs | RDA | ATP-dependent molecular chaperone HSP82 | / | 0.575 | |
| 2iwu | NP5 | ATP-dependent molecular chaperone HSP82 | / | 0.573 | |
| 2xk2 | ADP | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 3r4p | FU7 | Heat shock protein HSP 90-alpha | / | 0.569 | |
| 2o1u | ANP | Endoplasmin | / | 0.567 | |
| 2xx4 | 13I | ATP-dependent molecular chaperone HSP82 | / | 0.567 | |
| 2bre | KJ2 | ATP-dependent molecular chaperone HSP82 | / | 0.563 | |
| 3peh | IBD | Endoplasmin homolog, putative | / | 0.560 | |
| 4ce2 | BO5 | ATP-dependent molecular chaperone HSP82 | / | 0.560 | |
| 3rlr | 3RR | Heat shock protein HSP 90-alpha | / | 0.559 | |
| 3c11 | GDM | ATP-dependent molecular chaperone HSP82 | / | 0.558 | |
| 2qg0 | A94 | Heat shock protein HSP 90-alpha | / | 0.556 | |
| 4gqt | ADP | Heat shock protein 90 | / | 0.556 | |
| 2byh | 2D7 | Heat shock protein HSP 90-alpha | / | 0.554 | |
| 2esa | GDM | Endoplasmin | / | 0.554 | |
| 3hhu | 819 | Heat shock protein HSP 90-alpha | / | 0.554 | |
| 1yc1 | 4BC | Heat shock protein HSP 90-alpha | / | 0.552 | |
| 1byq | ADP | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 4b7p | 9UN | Heat shock protein HSP 90-alpha | / | 0.551 | |
| 3ied | AN2 | HSP90 | / | 0.548 | |
| 4egi | B2J | Heat shock protein HSP 90-alpha | / | 0.546 | |
| 2wer | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.544 | |
| 1amw | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.543 | |
| 2xd6 | XD6 | ATP-dependent molecular chaperone HSP82 | / | 0.543 | |
| 4jql | VJ6 | Heat shock protein HSP 90-alpha | / | 0.543 | |
| 1qy5 | NEC | Endoplasmin | / | 0.542 | |
| 2zkj | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.541 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.540 | |
| 2vw5 | BC6 | ATP-dependent molecular chaperone HSP82 | / | 0.539 | |
| 3b28 | B2X | Heat shock protein HSP 90-alpha | / | 0.539 | |
| 4ce1 | 7FK | ATP-dependent molecular chaperone HSP82 | / | 0.539 | |
| 4xdm | GDM | Heat shock cognate 90 kDa protein | / | 0.539 | |
| 3eko | PYU | Heat shock protein HSP 90-alpha | / | 0.537 | |
| 3vha | VHA | Heat shock protein HSP 90-alpha | / | 0.535 | |
| 1bgq | RDC | ATP-dependent molecular chaperone HSP82 | / | 0.534 | |
| 2bz5 | AB4 | Heat shock protein HSP 90-alpha | / | 0.534 | |
| 3q5l | KX2 | Heat shock protein 83-1 | / | 0.534 | |
| 2brc | CT5 | ATP-dependent molecular chaperone HSP82 | / | 0.533 | |
| 3t0z | ATP | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 3wha | WHA | Heat shock protein HSP 90-alpha | / | 0.531 | |
| 2iws | NP4 | ATP-dependent molecular chaperone HSP82 | / | 0.530 | |
| 2xhr | C0P | Heat shock protein HSP 90-alpha | / | 0.530 | |
| 4ivg | ANP | TNF receptor-associated protein 1 | / | 0.530 | |
| 3r4o | FU3 | Heat shock protein HSP 90-alpha | / | 0.529 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.529 | |
| 3rlp | 3RP | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 4eft | EFT | Heat shock protein HSP 90-alpha | / | 0.528 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.527 | |
| 2wi5 | ZZ5 | Heat shock protein HSP 90-alpha | / | 0.525 | |
| 3t1k | ANP | Heat shock protein HSP 90-alpha | / | 0.523 | |
| 2wep | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.522 | |
| 1yc4 | 43P | Heat shock protein HSP 90-alpha | / | 0.520 | |
| 2bu8 | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.519 | |
| 4as9 | 4QS | ATP-dependent molecular chaperone HSP82 | / | 0.519 | |
| 2xcm | ADP | Cytosolic heat shock protein 90 | / | 0.517 | |
| 1am1 | ADP | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 2o1v | ADP | Endoplasmin | / | 0.515 | |
| 4ce3 | L4V | ATP-dependent molecular chaperone HSP82 | / | 0.515 | |
| 2cgf | P2N | ATP-dependent molecular chaperone HSP82 | / | 0.514 | |
| 3hyz | 42C | Heat shock protein HSP 90-alpha | / | 0.514 | |
| 2ior | ADP | Chaperone protein HtpG | / | 0.513 | |
| 3k99 | PFT | Heat shock protein HSP 90-alpha | / | 0.513 | |
| 2xab | VHD | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 3k97 | 4CD | Heat shock protein HSP 90-alpha | / | 0.512 | |
| 4xcl | AGS | Heat shock cognate 90 kDa protein | / | 0.510 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.509 | |
| 1i5c | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.509 | |
| 1u0y | PA7 | Endoplasmin | / | 0.509 | |
| 4xc0 | ACP | Heat shock cognate 90 kDa protein | / | 0.509 | |
| 1uy7 | PU4 | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 1yt0 | ADP | Endoplasmin | / | 0.507 | |
| 2iwx | M1S | ATP-dependent molecular chaperone HSP82 | / | 0.507 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.507 | |
| 4asf | 62U | ATP-dependent molecular chaperone HSP82 | / | 0.507 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.506 | |
| 2e0a | ANP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.505 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.504 | |
| 4egk | RDC | Heat shock protein HSP 90-alpha | / | 0.503 | |
| 2ykj | YKJ | Heat shock protein HSP 90-alpha | / | 0.502 | |
| 1nhh | ANP | DNA mismatch repair protein MutL | / | 0.499 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 3hek | BD0 | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 3k98 | 1RC | Heat shock protein HSP 90-alpha | / | 0.499 | |
| 3hz1 | 42C | Heat shock protein HSP 90-alpha | / | 0.498 | |
| 2vwc | BC2 | ATP-dependent molecular chaperone HSP82 | / | 0.497 | |
| 4bqg | 50Q | Heat shock protein HSP 90-alpha | / | 0.497 | |
| 4asg | 814 | ATP-dependent molecular chaperone HSP82 | / | 0.496 | |
| 5bsf | NAD | Pyrroline-5-carboxylate reductase | / | 0.495 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.494 | |
| 2bt0 | CT5 | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 3r4n | FU5 | Heat shock protein HSP 90-alpha | / | 0.493 | |
| 2bu2 | ATP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.492 | |
| 1nzf | UPG | DNA beta-glucosyltransferase | / | 0.491 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.491 | |
| 3opd | HIE | Heat shock protein 83 | / | 0.490 | |
| 2yi5 | YI5 | Heat shock protein HSP 90-alpha | / | 0.489 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.488 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.486 | |
| 3pej | BC2 | Endoplasmin homolog, putative | / | 0.482 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.480 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.480 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.479 | |
| 3uib | SB2 | Putative mitogen-activated protein kinase | / | 0.478 | |
| 1jpa | ANP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.477 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.477 | |
| 2chw | 039 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.477 | |
| 2wi6 | ZZ6 | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 2xjx | XJX | Heat shock protein HSP 90-alpha | / | 0.477 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.477 | |
| 4nxv | GDP | Mitochondrial dynamics protein MID51 | / | 0.476 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.475 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.475 | |
| 4gk3 | L87 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.475 | |
| 1zrz | BI1 | Protein kinase C iota type | 2.7.11.13 | 0.474 | |
| 2qo9 | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.474 | |
| 3frq | ERY | Erythromycin resistance repressor protein | / | 0.474 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.473 | |
| 2itn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.473 | |
| 2yki | YKI | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 2hma | SAM | tRNA-specific 2-thiouridylase MnmA | / | 0.472 | |
| 2x0r | NAD | Malate dehydrogenase | / | 0.472 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.472 | |
| 2oap | ANP | Type II secretion system protein (GspE-2) | / | 0.471 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.471 | |
| 4yr9 | NAD | L-threonine 3-dehydrogenase, mitochondrial | 1.1.1.103 | 0.471 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.470 | |
| 2ykb | YKB | Heat shock protein HSP 90-alpha | / | 0.470 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.470 | |
| 3d8v | UD1 | Bifunctional protein GlmU | / | 0.470 | |
| 4die | C5P | Cytidylate kinase | / | 0.470 | |
| 5f5r | ANP | Heat shock protein 75 kDa, mitochondrial | / | 0.470 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.469 | |
| 3hz5 | Z64 | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 4egh | 0OY | Heat shock protein HSP 90-alpha | / | 0.469 | |
| 4fuy | EK2 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.469 | |
| 4xiv | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.469 | |
| 1fm7 | DFV | Chalcone--flavonone isomerase 1 | 5.5.1.6 | 0.468 | |
| 2acx | ANP | G protein-coupled receptor kinase 6 | 2.7.11.16 | 0.468 | |
| 2ahv | COA | Acetate CoA-transferase YdiF | 2.8.3.8 | 0.468 | |
| 2bsm | BSM | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 2ghl | LIB | Mitogen-activated protein kinase 14 | / | 0.468 | |
| 2yej | ZZ3 | Heat shock protein HSP 90-alpha | / | 0.468 | |
| 3h4l | ANP | DNA mismatch repair protein PMS1 | / | 0.468 | |
| 3inm | NDP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.468 | |
| 3wbb | NAP | Meso-diaminopimelate D-dehydrogenase | / | 0.468 | |
| 2yjw | YJW | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 1p44 | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.466 | |
| 2izr | BRK | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.466 | |
| 2xjj | L81 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.466 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.465 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.465 | |
| 2c1a | I5S | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.465 | |
| 2cch | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.465 | |
| 2vcj | 2EQ | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 2wi1 | ZZ2 | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 2yk2 | YJW | Heat shock protein HSP 90-alpha | / | 0.465 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.465 | |
| 3qiy | QI1 | Botulinum neurotoxin type A | 3.4.24.69 | 0.465 | |
| 3r04 | UNQ | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.465 | |
| 4ia1 | BIV | Vitamin D3 receptor A | / | 0.465 | |
| 4oa9 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.465 | |
| 4yaw | 2AM | NADPH--cytochrome P450 reductase | / | 0.465 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.464 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.464 | |
| 2nnq | T4B | Fatty acid-binding protein, adipocyte | / | 0.464 | |
| 2yi6 | 6QM | Heat shock protein HSP 90-alpha | / | 0.464 | |
| 4hw3 | 19G | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.464 | |
| 4yaf | 2AM | NADPH--cytochrome P450 reductase | / | 0.464 | |
| 2yei | XQI | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 3fr4 | F8A | Fatty acid-binding protein, adipocyte | / | 0.463 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.463 | |
| 3ump | ATP | ATP-dependent 6-phosphofructokinase isozyme 2 | 2.7.1.11 | 0.463 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.463 | |
| 2itv | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.462 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.462 | |
| 3kb1 | ADP | Iron-sulfur cluster carrier protein | / | 0.462 | |
| 3nga | 3NG | Casein kinase II subunit alpha | 2.7.11.1 | 0.462 | |
| 3s2a | 2NQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.462 | |
| 4g2f | C07 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.462 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.461 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.461 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.461 | |
| 3mdm | FJZ | Cholesterol 24-hydroxylase | / | 0.461 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.461 | |
| 4fcq | 2N6 | Heat shock protein HSP 90-alpha | / | 0.461 | |
| 4gk2 | L66 | Ephrin type-A receptor 3 | 2.7.10.1 | 0.461 | |
| 4qmx | H8H | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.461 | |
| 5dt9 | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.461 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.461 | |
| 1hqu | HBY | Gag-Pol polyprotein | 2.7.7.49 | 0.460 | |
| 3da1 | FAD | Glycerol-3-phosphate dehydrogenase | / | 0.460 | |
| 3omu | IBD | Heat shock protein 83 | / | 0.460 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase alpha chain | 1.13.11.3 | 0.460 | |
| 3pce | 3HP | Protocatechuate 3,4-dioxygenase beta chain | 1.13.11.3 | 0.460 | |
| 4fjy | FJY | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.460 | |
| 4v12 | POG | MaoC like domain protein | / | 0.460 | |
| 2fna | ADP | Uncharacterized protein | / | 0.459 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.459 | |
| 2r2n | KYN | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.459 | |
| 2zsh | GA3 | Gibberellin receptor GID1A | 3 | 0.459 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.459 | |
| 4efu | EFU | Heat shock protein HSP 90-alpha | / | 0.459 | |
| 5ack | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.459 | |
| 1cjt | FOK | Adenylate cyclase type 2 | / | 0.458 | |
| 1cjt | FOK | Adenylate cyclase type 5 | / | 0.458 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.458 | |
| 2b9f | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.458 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.458 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.458 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.458 | |
| 5c8w | PCG | cGMP-dependent protein kinase 2 | 2.7.11.12 | 0.458 | |
| 2hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.457 | |
| 3irm | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.457 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.457 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1h69 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.456 | |
| 1y4s | ADP | Chaperone protein HtpG | / | 0.456 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.456 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.456 | |
| 3nd1 | SAH | Precorrin-6A synthase (Deacetylating) | / | 0.456 | |
| 4q5j | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.456 | |
| 4y7c | NAP | NADPH--cytochrome P450 reductase | / | 0.456 | |
| 5ftf | ADP | TPR domain protein | / | 0.456 | |
| 1dxo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.455 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.455 | |
| 1i5a | ACP | Chemotaxis protein CheA | 2.7.13.3 | 0.455 | |
| 1ia3 | TQ5 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.455 | |
| 2dq7 | STU | Tyrosine-protein kinase Fyn | 2.7.10.2 | 0.455 | |
| 2qoc | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.455 | |
| 3vs2 | VSB | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.455 | |
| 4gj3 | 0XP | Non-receptor tyrosine-protein kinase TYK2 | 2.7.10.2 | 0.455 | |
| 4nt0 | 3DU | Orotidine 5'-phosphate decarboxylase | 4.1.1.23 | 0.455 | |
| 4o70 | 1QK | Bromodomain-containing protein 4 | / | 0.455 | |
| 1nvq | UCN | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.454 | |
| 1pvg | ANP | DNA topoisomerase 2 | 5.99.1.3 | 0.454 | |
| 1uu8 | BI1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.454 | |
| 2cct | 2E1 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.454 | |
| 2hrc | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 2py3 | ACP | Fibroblast growth factor receptor 2 | / | 0.454 | |
| 2q9f | C3S | Cholesterol 24-hydroxylase | / | 0.454 | |
| 2vci | 2GJ | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 3cuk | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.454 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 4m2x | TMQ | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1o0s | NAI | NAD-dependent malic enzyme, mitochondrial | 1.1.1.38 | 0.453 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.453 | |
| 2c3q | GTX | Glutathione S-transferase theta-1 | 2.5.1.18 | 0.453 | |
| 2qoq | ANP | Ephrin type-A receptor 3 | 2.7.10.1 | 0.453 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.453 | |
| 4g3r | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.453 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.453 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.452 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.452 | |
| 2bun | FAD | AppA protein | / | 0.452 | |
| 2c3k | ABO | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.452 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.452 | |
| 2zdx | P4A | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.452 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.452 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.452 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.451 | |
| 1h1w | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 1h66 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.451 | |
| 1qpd | STU | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 1z5a | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.451 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.451 | |
| 2vwz | 7X6 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.451 | |
| 2ye4 | 2FY | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 3mtf | A3F | Activin receptor type-1 | 2.7.11.30 | 0.451 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 3qk0 | QK0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.451 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.451 | |
| 4bzo | 676 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.451 | |
| 4ftt | 6HK | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.451 | |
| 4jlc | SU6 | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.451 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.451 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.450 | |
| 1o76 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.450 | |
| 1pn3 | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.450 | |
| 2hy0 | 306 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.450 | |
| 2mwg | FMN | Blue-light photoreceptor | / | 0.450 | |
| 4dpy | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.450 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4gfn | SUY | DNA gyrase subunit B | / | 0.450 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 4riy | ADP | Epidermal growth factor receptor | 2.7.10.1 | 0.450 | |
| 4xx9 | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.450 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 1tdr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.449 | |
| 2j3j | HC4 | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.449 | |
| 2qfo | A13 | Heat shock protein HSP 90-alpha | / | 0.449 | |
| 3sc1 | 3S1 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 4fv7 | E94 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.449 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.449 | |
| 4ly9 | 1YY | Glucokinase regulatory protein | / | 0.449 | |
| 5a3c | NAD | SIR2 family protein | / | 0.449 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.449 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.448 | |
| 1ezv | UQ6 | Cytochrome b | / | 0.448 | |
| 1np7 | FAD | Cryptochrome DASH | / | 0.448 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.448 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.448 | |
| 2bbw | GP5 | Adenylate kinase 4, mitochondrial | / | 0.448 | |
| 2bdf | 24A | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.448 | |
| 2phk | ATP | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | 2.7.11.19 | 0.448 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.448 | |
| 2xa4 | AZ5 | Tyrosine-protein kinase JAK2 | / | 0.448 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 3a4o | STU | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.448 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.448 | |
| 3so9 | 017 | Pol protein | / | 0.448 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.448 | |
| 3tjs | D0R | Cytochrome P450 3A4 | / | 0.448 | |
| 4dym | IYZ | Activin receptor type-1 | 2.7.11.30 | 0.448 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.448 | |
| 4hgs | 15G | Casein kinase I isoform gamma-3 | 2.7.11.1 | 0.448 | |
| 4la0 | 198 | Serum albumin | / | 0.448 | |
| 4ock | ANP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.448 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.448 | |
| 1aj8 | COA | Citrate synthase | / | 0.447 | |
| 1f17 | NAI | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.447 | |
| 1i58 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.447 | |
| 1o5r | FR9 | Adenosine deaminase | 3.5.4.4 | 0.447 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.447 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2f3m | GTD | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.447 | |
| 2hkj | RDC | Type 2 DNA topoisomerase 6 subunit B | / | 0.447 | |
| 2nry | STU | Interleukin-1 receptor-associated kinase 4 | 2.7.11.1 | 0.447 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.447 | |
| 2wpa | 889 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.447 | |
| 2xhx | T5M | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 2yec | XQ0 | Heat shock protein HSP 90-alpha | / | 0.447 | |
| 3a4v | NAD | NDP-sugar epimerase | / | 0.447 | |
| 3au8 | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic | 1.1.1.267 | 0.447 | |
| 3ceh | AVE | Glycogen phosphorylase, liver form | 2.4.1.1 | 0.447 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 4hms | FMN | Phenazine biosynthesis protein PhzG | 1.4 | 0.447 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.447 | |
| 4kzo | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.447 | |
| 4mv1 | ADP | Biotin carboxylase | 6.3.4.14 | 0.447 | |
| 4qmw | KS1 | Serine/threonine-protein kinase 24 | 2.7.11.1 | 0.447 | |
| 5aab | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.447 | |
| 5ajq | DB8 | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.447 | |
| 5e8w | STU | TGF-beta receptor type-1 | 2.7.11.30 | 0.447 | |
| 1dj3 | GDP | Adenylosuccinate synthetase, chloroplastic | / | 0.446 | |
| 1hdg | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.446 | |
| 1mf0 | GDP | Adenylosuccinate synthetase isozyme 1 | / | 0.446 | |
| 1qrr | UPG | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.446 | |
| 1tll | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.446 | |
| 2ok7 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.446 | |
| 2vpr | TDC | Tetracycline repressor protein class H | / | 0.446 | |
| 2vwx | 7X4 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.446 | |
| 3apf | BMW | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial | 1.2.4.1 | 0.446 | |
| 3exh | TPP | Pyruvate dehydrogenase E1 component subunit beta, mitochondrial | 1.2.4.1 | 0.446 | |
| 3mdv | CL6 | Cholesterol 24-hydroxylase | / | 0.446 | |
| 3rv9 | RVD | Salicylate synthase | / | 0.446 | |
| 3vjo | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.446 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.446 | |
| 4o0r | X4Z | Serine/threonine-protein kinase PAK 1 | 2.7.11.1 | 0.446 | |
| 4xj4 | 3AT | Cyclic GMP-AMP synthase | / | 0.446 | |
| 5a3b | APR | SIR2 family protein | / | 0.446 | |
| 1rkx | NAD | CDP-D-glucose-4,6-dehydratase | / | 0.445 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 1xjj | DGT | Vitamin B12-dependent ribonucleotide reductase | / | 0.445 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2itp | AEE | Epidermal growth factor receptor | 2.7.10.1 | 0.445 | |
| 2wq6 | FAD | RE11660p | / | 0.445 | |
| 2y6o | 1N1 | Ephrin type-A receptor 4 | 2.7.10.1 | 0.445 | |
| 3cy2 | MB9 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.445 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3r1k | COA | N-acetyltransferase Eis | / | 0.445 | |
| 3upf | 0BU | Polyprotein | / | 0.445 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.445 | |
| 4anw | O92 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 4cax | 646 | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.445 | |
| 4fr4 | STU | Serine/threonine-protein kinase 32A | 2.7.11.1 | 0.445 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.445 | |
| 4l04 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.445 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.445 | |
| 1adf | TAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 1kvt | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.444 | |
| 1t88 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 1uu3 | LY4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.444 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.444 | |
| 1z59 | ADP | Type 2 DNA topoisomerase 6 subunit B | / | 0.444 | |
| 2g0n | GDP | Ras-related C3 botulinum toxin substrate 3 | / | 0.444 | |
| 2itq | ITQ | Epidermal growth factor receptor | 2.7.10.1 | 0.444 | |
| 2wih | P48 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 2z6j | TUI | 2-nitropropane dioxygenase | / | 0.444 | |
| 3drc | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.444 | |
| 3hdh | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.444 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.444 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.444 | |
| 3l8p | 0CE | Angiopoietin-1 receptor | 2.7.10.1 | 0.444 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3pxy | JWS | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.444 | |
| 3zew | STU | Ephrin type-B receptor 4 | 2.7.10.1 | 0.444 | |
| 4anq | VGH | ALK tyrosine kinase receptor | 2.7.10.1 | 0.444 | |
| 4c58 | 824 | Cyclin-G-associated kinase | 2.7.11.1 | 0.444 | |
| 4c9p | CAM | Cytochrome P450 | / | 0.444 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4fgg | 0U5 | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.444 | |
| 4j03 | FVS | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.444 | |
| 4jb1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.444 | |
| 4kuo | RBF | Putative blue-light photoreceptor | / | 0.444 | |
| 4wuo | NAD | 3-isopropylmalate dehydrogenase | 1.1.1.85 | 0.444 | |
| 4y9u | NAP | NADPH--cytochrome P450 reductase | / | 0.444 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.443 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.443 | |
| 1kif | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.443 | |
| 1p31 | EPU | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.443 | |
| 1pnv | TYD | dTDP-epi-vancosaminyltransferase | 2.4.1.311 | 0.443 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 2bik | BI1 | Serine/threonine-protein kinase pim-1 | 2.7.11.1 | 0.443 | |
| 2o7p | NAP | Riboflavin biosynthesis protein RibD | / | 0.443 | |
| 2qbm | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2vwq | NAP | Glucose 1-dehydrogenase | / | 0.443 | |
| 2y4g | TIR | TamL | / | 0.443 | |
| 2z6d | FMN | Phototropin-2 | 2.7.11.1 | 0.443 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.443 | |
| 3k9v | CPS | 1,25-dihydroxyvitamin D(3) 24-hydroxylase, mitochondrial | / | 0.443 | |
| 3mg3 | ECH | Orange carotenoid-binding protein | / | 0.443 | |
| 3ojl | NAD | Cap5O | / | 0.443 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.443 | |
| 3uwq | U5P | Orotidine 5'-phosphate decarboxylase | / | 0.443 | |
| 3v5j | 0F2 | Tyrosine-protein kinase ITK/TSK | 2.7.10.2 | 0.443 | |
| 4a30 | QMI | Glycylpeptide N-tetradecanoyltransferase | / | 0.443 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4dre | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.443 | |
| 4h50 | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.443 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.443 | |
| 4ruo | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 4wh2 | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.443 | |
| 1b2l | NDC | Alcohol dehydrogenase | 1.1.1.1 | 0.442 | |
| 1e8z | STU | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 1kqo | DND | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.442 | |
| 1t87 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 1thn | ADP | Anti-sigma F factor | / | 0.442 | |
| 1vyw | 292 | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.442 | |
| 2cmj | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.442 | |
| 2hen | ADP | Ephrin type-B receptor 2 | 2.7.10.1 | 0.442 | |
| 2itx | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.442 | |
| 2oj9 | BMI | Insulin-like growth factor 1 receptor | 2.7.10.1 | 0.442 | |
| 2xck | MH4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.442 | |
| 2ym5 | YM5 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.442 | |
| 3mvm | 39P | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.442 | |
| 3qe2 | FAD | NADPH--cytochrome P450 reductase | / | 0.442 | |
| 4ekl | 0RF | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.442 | |
| 4ezl | 0SE | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.442 | |
| 4h8n | NDP | NADPH-dependent conjugated polyketone reductase C2 | / | 0.442 | |
| 4hnf | 16W | Casein kinase I isoform delta | 2.7.11.1 | 0.442 | |
| 4mp7 | PFT | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial | 2.7.11.2 | 0.442 | |
| 4r3a | RBF | Blue-light-activated histidine kinase 2 | 2.7.13.3 | 0.442 | |
| 5a9s | NAP | Putative dehydrogenase | / | 0.442 | |
| 5ar4 | SB2 | Receptor-interacting serine/threonine-protein kinase 2 | 2.7.11.1 | 0.442 | |
| 1dir | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.441 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1i59 | ADP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1i5b | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.441 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.441 | |
| 2rkv | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.441 | |
| 2vx1 | 7X8 | Ephrin type-B receptor 4 | 2.7.10.1 | 0.441 | |
| 2zax | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 2zva | 1N1 | Tyrosine-protein kinase Lyn | 2.7.10.2 | 0.441 | |
| 3flw | FLW | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 3mvq | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.441 | |
| 3rud | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.441 | |
| 3s1d | ZIR | Cytokinin dehydrogenase 1 | 1.5.99.12 | 0.441 | |
| 3wrj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 4bid | IE8 | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.441 | |
| 4e8y | IHA | D-beta-D-heptose 7-phosphate kinase | / | 0.441 | |
| 4f6w | 0SS | Cyclin-dependent kinase 8 | 2.7.11.22 | 0.441 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.441 | |
| 4h2n | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.441 | |
| 4h95 | 06U | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4iwq | 1FV | Serine/threonine-protein kinase TBK1 | 2.7.11.1 | 0.441 | |
| 4j95 | ACP | Fibroblast growth factor receptor 2 | / | 0.441 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.441 | |
| 5cnn | ANP | Epidermal growth factor receptor | 2.7.10.1 | 0.441 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dz6 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1ewy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.440 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.440 | |
| 1nvs | UCM | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 1q97 | ATP | Serine/threonine-protein kinase SKY1 | 2.7.11.1 | 0.440 | |
| 1qxo | FMN | Chorismate synthase | / | 0.440 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.440 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.440 | |
| 2brg | DFY | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.440 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.440 | |
| 2nq8 | ZID | Enoyl-ACP reductase | / | 0.440 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.440 | |
| 3ac2 | KSE | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.440 | |
| 3fgo | CZA | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.440 | |
| 3lpb | NVB | Tyrosine-protein kinase JAK2 | / | 0.440 | |
| 3qaq | QAQ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 3zhr | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.440 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4e4q | RRH | Peroxisome proliferator-activated receptor gamma | / | 0.440 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.440 | |
| 4l4e | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 |