Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.3

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
2bl9CP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.31.000
2blbCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.635
1klkPMDDihydrofolate reductase1.5.1.30.625
3um5CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.619
3cseN22Uncharacterized protein/0.616
4h9614QDihydrofolate reductase1.5.1.30.615
4h9506UDihydrofolate reductase1.5.1.30.608
2blcCP7Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.602
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.602
4h9814QUncharacterized protein/0.598
1j3iWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.594
3dg8RJ6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.594
3qgtCP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.594
1j3jCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.591
3um61CYBifunctional dihydrofolate reductase-thymidylate synthase/0.588
3qg2CP6Bifunctional dihydrofolate reductase-thymidylate synthase/0.586
3qlzQLZUncharacterized protein/0.584
4g8zTOPDihydrofolate reductase1.5.1.30.584
2cd2FOLDihydrofolate reductase1.5.1.30.579
4ixeIXEDihydrofolate reductase1.5.1.30.579
3qls55VDihydrofolate reductase1.5.1.30.578
4kfj1R0Dihydrofolate reductase1.5.1.30.576
1bozPRDDihydrofolate reductase1.5.1.30.575
3qlrQLRDihydrofolate reductase1.5.1.30.574
3dgaRJ1Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.571
4dp3MMVBifunctional dihydrofolate reductase-thymidylate synthase/0.568
1aoeGW3Dihydrofolate reductase1.5.1.30.567
1hfqMOTDihydrofolate reductase1.5.1.30.565
3eek53SUncharacterized protein/0.565
1cd2FOLDihydrofolate reductase1.5.1.30.563
3irn1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.563
4dpdDHFBifunctional dihydrofolate reductase-thymidylate synthase/0.563
2w3aTOPDihydrofolate reductase1.5.1.30.561
1m78CLZDihydrofolate reductase1.5.1.30.560
1dg5TOPDihydrofolate reductase1.5.1.30.559
2blaCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.559
3qlxQLRUncharacterized protein/0.558
4h9753SDihydrofolate reductase1.5.1.30.557
3eem53VUncharacterized protein/0.556
1hfpMOTDihydrofolate reductase1.5.1.30.555
3sai9DRDihydrofolate reductase/0.555
1ia1TQ3Dihydrofolate reductase1.5.1.30.554
3nxoD2BDihydrofolate reductase1.5.1.30.553
3sa16DRDihydrofolate reductase/0.553
4kd79DRDihydrofolate reductase1.5.1.30.553
3kjsDQ1Bifunctional dihydrofolate reductase-thymidylate synthase/0.551
1vj3TABDihydrofolate reductase1.5.1.30.550
2w3wVG9Dihydrofolate reductase/0.550
3qly55VUncharacterized protein/0.550
3rg9WRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.550
3eej53RUncharacterized protein/0.548
3eel53TUncharacterized protein/0.547
3jwm5WBDihydrofolate reductase/0.547
2fzhDH1Dihydrofolate reductase1.5.1.30.546
2w3vTOPDihydrofolate reductase/0.546
5cccDDFDihydrofolate reductase1.5.1.30.543
3k47D09Dihydrofolate reductase1.5.1.30.542
4kbn25UDihydrofolate reductase1.5.1.30.542
3jwcEKBDihydrofolate reductase/0.541
3nxvD2FDihydrofolate reductase1.5.1.30.541
3iro2CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.540
3qlwN22Dihydrofolate reductase1.5.1.30.539
4kak06UDihydrofolate reductase1.5.1.30.539
1s3wTQTDihydrofolate reductase1.5.1.30.537
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.537
3nxrD2DDihydrofolate reductase1.5.1.30.533
3sa27DRDihydrofolate reductase/0.533
3um81CYBifunctional dihydrofolate reductase-thymidylate synthase/0.533
4x5fFOLDihydrofolate reductase1.5.1.30.533
1m7aMQUDihydrofolate reductase1.5.1.30.531
3invC50Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.530
1ddsMTXDihydrofolate reductase1.5.1.30.529
3clbTMQBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.529
3nxtD2EDihydrofolate reductase1.5.1.30.529
3sh25DRDihydrofolate reductase1.5.1.30.529
3jsuKA5Bifunctional dihydrofolate reductase-thymidylate synthase/0.528
3oafOAGDihydrofolate reductase1.5.1.30.528
1m79MQ1Dihydrofolate reductase1.5.1.30.526
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.526
3ql3FOLDihydrofolate reductase1.5.1.30.525
3i8aN22Dihydrofolate reductase1.5.1.30.524
4ixgIXGDihydrofolate reductase1.5.1.30.524
4cd2FOLDihydrofolate reductase1.5.1.30.523
4fgg0U5Dihydrofolate reductase1.5.1.30.522
4nx7FOLDihydrofolate reductase1.5.1.30.521
1ia4TQ6Dihydrofolate reductase1.5.1.30.520
3dfrMTXDihydrofolate reductase1.5.1.30.520
3nxyD2HDihydrofolate reductase1.5.1.30.519
3cd2MTXDihydrofolate reductase1.5.1.30.518
4fhbFOLDihydrofolate reductase1.5.1.30.518
1fmjRTLRetinol dehydratase/0.517
1df7MTXDihydrofolate reductase1.5.1.30.515
4p68MTXDihydrofolate reductase/0.515
1dr4HBIDihydrofolate reductase1.5.1.30.513
1rx5DDFDihydrofolate reductase1.5.1.30.513
1ra2FOLDihydrofolate reductase1.5.1.30.511
1dg7WRBDihydrofolate reductase1.5.1.30.510
1e26GPBDihydrofolate reductase1.5.1.30.509
1og5SWFCytochrome P450 2C9/0.508
3freTOPDihydrofolate reductase1.5.1.30.508
3r336MEDihydrofolate reductase1.5.1.30.506
1ia2TQ4Dihydrofolate reductase1.5.1.30.505
4j6cSTRCytochrome P450 monooxygenase/0.505
3vrwYS5Vitamin D3 receptor/0.503
2z97CAMCamphor 5-monooxygenase1.14.15.10.502
3eigMTXDihydrofolate reductase1.5.1.30.502
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.502
3tq8TOPDihydrofolate reductase/0.502
3tq9MTXDihydrofolate reductase/0.502
4nx6FOLDihydrofolate reductase1.5.1.30.502
4nkvAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.501
1ia3TQ5Dihydrofolate reductase1.5.1.30.500
2zbaZBATrichothecene 3-O-acetyltransferase/0.500
3nr4PYVAbscisic acid receptor PYL2/0.500
3och2MXDihydrofolate reductase1.5.1.30.500
4ixfIXFDihydrofolate reductase1.5.1.30.500
4m6l21VDihydrofolate reductase1.5.1.30.500
4g210VPVitamin D3 receptor A/0.499
3fywXCFDihydrofolate reductase1.5.1.30.498
4g95OAGDihydrofolate reductase1.5.1.30.498
1re7FOLDihydrofolate reductase1.5.1.30.497
1tbbROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.496
2chw039Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.496
4nky3QZSteroid 17-alpha-hydroxylase/17,20 lyase/0.496
1qzfFOLBifunctional dihydrofolate reductase-thymidylate synthase/0.495
2jedLG8Protein kinase C theta type2.7.11.130.494
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.494
1tdrMTXDihydrofolate reductase1.5.1.30.493
4kne1CYDihydrofolate reductase1.5.1.30.493
3ar7TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.492
3zy6GFBGDP-fucose protein O-fucosyltransferase 12.4.1.2210.492
4x5gFOLDihydrofolate reductase1.5.1.30.492
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.491
3nj0PYVAbscisic acid receptor PYL2/0.491
3srrQ20Dihydrofolate reductase1.5.1.30.491
4p66MTXDihydrofolate reductase/0.491
1ddrMTXDihydrofolate reductase1.5.1.30.489
3p99LNPLanosterol 14-alpha-demethylase/0.489
3sqyQ11Dihydrofolate reductase1.5.1.30.489
4ia3BIVVitamin D3 receptor A/0.489
1dyiFOLDihydrofolate reductase1.5.1.30.488
1j3kWRABifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.488
3ml8ML8Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.488
3vt65YIVitamin D3 receptor/0.488
1s3yTQTDihydrofolate reductase1.5.1.30.487
2x7hPFNProstaglandin reductase 310.487
3sgy06WDihydrofolate reductase1.5.1.30.487
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.486
2drcMTXDihydrofolate reductase1.5.1.30.486
2y46MIVMycinamicin IV hydroxylase/epoxidase/0.486
3lanKBTGag-Pol polyprotein2.7.7.490.486
4ipw1G7Mycocyclosin synthase1.14.21.90.486
1db1VDXVitamin D3 receptor/0.485
1rx2FOLDihydrofolate reductase1.5.1.30.485
2hcdBIVVitamin D3 receptor A/0.485
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.485
1dr3HBIDihydrofolate reductase1.5.1.30.484
3frfXCFDihydrofolate reductase1.5.1.30.484
4j6bPLOCytochrome P450 monooxygenase/0.484
2y98MIVMycinamicin IV hydroxylase/epoxidase/0.483
3a4pDFQHepatocyte growth factor receptor2.7.10.10.483
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
4jbtASDCytochrome P450 monooxygenase/0.483
3srsM23Dihydrofolate reductase1.5.1.30.482
4ejgNCTCytochrome P450 2A131.14.14.10.482
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.482
7dfrFOLDihydrofolate reductase1.5.1.30.482
1ao8MTXDihydrofolate reductase1.5.1.30.481
3vt9YI4Vitamin D3 receptor/0.481
4g1z0VPVitamin D3 receptor A/0.481
5cpbNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.481
3btjDEQHTH-type transcriptional regulator QacR/0.480
3jw5TOPDihydrofolate reductase/0.480
3ns2PYVAbscisic acid receptor PYL2/0.480
4m2xTMQDihydrofolate reductase1.5.1.30.480
4mv1ADPBiotin carboxylase6.3.4.140.480
1dyrTOPDihydrofolate reductase1.5.1.30.479
1kl2FONSerine hydroxymethyltransferase/0.479
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.479
3c14FOKAdenylate cyclase type 2/0.479
3c14FOKAdenylate cyclase type 5/0.479
1fmlRTLRetinol dehydratase/0.478
1lhwESMSex hormone-binding globulin/0.478
2feuCAMCamphor 5-monooxygenase1.14.15.10.478
2ph5NADHomospermidine synthase/0.478
3gwfFADCyclohexanone monooxygenase/0.478
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.478
1ludTRRDihydrofolate reductase1.5.1.30.477
1x8lOXRRetinol dehydratase/0.477
1yrdCAMCamphor 5-monooxygenase1.14.15.10.477
3lfcZ86Mitogen-activated protein kinase 14/0.477
3njoPYVAbscisic acid receptor PYR1/0.477
3nmpPYVAbscisic acid receptor PYL2/0.477
3p3zP3ZPutative cytochrome P450/0.477
3vtcTK3Vitamin D3 receptor/0.477
4ddrMMVDihydrofolate reductase1.5.1.30.477
4i8vBHFCytochrome P450 1A11.14.14.10.477
4jdaA9SAbscisic acid receptor PYL3/0.477
1dz6CAMCamphor 5-monooxygenase1.14.15.10.476
1f20FADNitric oxide synthase, brain1.14.13.390.476
1fp2HMOIsoflavone-7-O-methyltransferase 82.1.1.1500.476
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.476
1rx8FOLDihydrofolate reductase1.5.1.30.476
2vn0TDZCytochrome P450 2C8/0.476
3gobHXXDdmC/0.476
3vt5YI2Vitamin D3 receptor/0.476
4qjcIXEDihydrofolate reductase1.5.1.30.476
5d7q4I5NAD-dependent protein deacetylase sirtuin-23.5.10.476
1rx7FOLDihydrofolate reductase1.5.1.30.475
2hasC3OVitamin D3 receptor/0.475
3h3sH15Collagen type IV alpha-3-binding protein/0.475
3pm0BHFCytochrome P450 1B1/0.475
3w5rLOAVitamin D3 receptor/0.475
4fjz4FJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.475
4g1d0VKVitamin D3 receptor A/0.475
4r20AERCytochrome P450 family 17 polypeptide 2/0.475
1dhiMTXDihydrofolate reductase1.5.1.30.474
1dkfBMSRetinoic acid receptor alpha/0.474
1m13HYFNuclear receptor subfamily 1 group I member 2/0.474
2hw2RFPRifampin ADP-ribosyl transferase/0.474
2nv6ZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.474
3drcMTXDihydrofolate reductase1.5.1.30.474
3pre3REPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.474
3vt7VDXVitamin D3 receptor/0.474
4kjjFOLDihydrofolate reductase1.5.1.30.474
1dyhDZFDihydrofolate reductase1.5.1.30.473
1ly4COQDihydrofolate reductase1.5.1.30.473
1ohjCOPDihydrofolate reductase1.5.1.30.473
3fwiCAMCamphor 5-monooxygenase1.14.15.10.473
4ejh0QACytochrome P450 2A131.14.14.10.473
4fad0TBPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.473
4ia7BIVVitamin D3 receptor A/0.473
4jlj1NMDeoxycytidine kinase2.7.1.740.473
4l49CAMCamphor 5-monooxygenase1.14.15.10.473
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.472
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.472
3a783EVVitamin D3 receptor/0.472
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.472
4cdmFO1Deoxyribodipyrimidine photolyase/0.472
4iteTEYVitamin D3 receptor/0.472
4j6dTESCytochrome P450 monooxygenase/0.472
4l4aCAMCamphor 5-monooxygenase1.14.15.10.472
1phgMYTCamphor 5-monooxygenase1.14.15.10.471
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.471
3qlhT27Gag-Pol polyprotein2.7.7.490.471
4gg70J8Hepatocyte growth factor receptor2.7.10.10.471
1dreMTXDihydrofolate reductase1.5.1.30.470
1iwiCAMCamphor 5-monooxygenase1.14.15.10.470
1mvsDTMDihydrofolate reductase1.5.1.30.470
1nq7ARLNuclear receptor ROR-beta/0.470
2nq8ZIDEnoyl-ACP reductase/0.470
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.470
3l6jZ90Alr2278 protein/0.470
3qm4PN0Cytochrome P450 2D6/0.470
3tmz06XCytochrome P450 2B41.14.14.10.470
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.470
1cjkFOKAdenylate cyclase type 2/0.469
1cjkFOKAdenylate cyclase type 5/0.469
1i58ACPChemotaxis protein CheA2.7.13.30.469
4bgiI4IEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.469
4elb34RDihydrofolate reductase/0.469
4g3rCAMCamphor 5-monooxygenase1.14.15.10.469
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.469
4pdaCTNNucleoside permease/0.469
1c1bGCAGag-Pol polyprotein2.7.7.490.468
1e7vLY2Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
1p44GEQEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
1pd8CO4Dihydrofolate reductase1.5.1.30.468
1ra3MTXDihydrofolate reductase1.5.1.30.468
1ysx4EBSerum albumin/0.468
1zidZIDEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
2aqhNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.468
2w0bCMWLanosterol 14-alpha demethylase1.14.13.700.468
3c3dFO12-phospho-L-lactate transferase/0.468
3frdDHFDihydrofolate reductase1.5.1.30.468
3fy9XCFDihydrofolate reductase1.5.1.30.468
4cukNAID-lactate dehydrogenase/0.468
4dvq1CACytochrome P450 11B2, mitochondrial1.14.15.40.468
1ewyFADFerredoxin--NADP reductase1.18.1.20.467
1jolFFODihydrofolate reductase1.5.1.30.467
1s9eADBGag-Pol polyprotein2.7.7.490.467
1sr7MOFProgesterone receptor/0.467
1t88CAMCamphor 5-monooxygenase1.14.15.10.467
1xu9CPSCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.467
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.467
1yrcCAMCamphor 5-monooxygenase1.14.15.10.467
2dqsTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.467
2q66ATPPoly(A) polymerase2.7.7.190.467
2w6oOA3Biotin carboxylase6.3.4.140.467
3ixp834Ecdysone receptor/0.467
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.467
4biiPYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.467
1ie8KH1Vitamin D3 receptor/0.466
1upw444Oxysterols receptor LXR-beta/0.466
1xddAAYIntegrin alpha-L/0.466
2fzjDH3Dihydrofolate reductase1.5.1.30.466
2hb8MVDVitamin D3 receptor/0.466
2qblCAMCamphor 5-monooxygenase1.14.15.10.466
3a1l2CCCytochrome P450/0.466
3d5qT30Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
3gc9B45Mitogen-activated protein kinase 112.7.11.240.466
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.466
4eufNADTrans-2-enoyl-CoA reductase [NADH]/0.466
4ia1BIVVitamin D3 receptor A/0.466
4j03FVSBifunctional epoxide hydrolase 23.1.3.760.466
1nhz486Glucocorticoid receptor/0.465
1rh3MTXDihydrofolate reductase1.5.1.30.465
1rkhVD2Vitamin D3 receptor/0.465
2zaxCAMCamphor 5-monooxygenase1.14.15.10.465
3antS82Bifunctional epoxide hydrolase 23.3.2.100.465
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.465
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.465
3fcoIIGCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.465
3srwQ27Dihydrofolate reductase1.5.1.30.465
3tqbFOLDihydrofolate reductase/0.465
4anuEM7Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.465
1g4sTPSThiamine-phosphate synthase/0.464
1l2jETCEstrogen receptor beta/0.464
2c7gFADNADPH-ferredoxin reductase FprA1.18.1.20.464
3mdvCL6Cholesterol 24-hydroxylase/0.464
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.464
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.464
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.464
1rb2FOLDihydrofolate reductase1.5.1.30.463
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.463
2fpcSCGStrictosidine synthase4.3.3.20.463
2q70DC8Estrogen receptor/0.463
2rhrEMOPutative ketoacyl reductase1.3.10.463
3c0g3AMPeripheral plasma membrane protein CASK2.7.11.10.463
3kb0A8SAbscisic acid receptor PYL2/0.463
3l63CAMCamphor 5-monooxygenase1.14.15.10.463
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.463
3sruQ26Dihydrofolate reductase1.5.1.30.463
3vrvYSDVitamin D3 receptor/0.463
4eilFOLBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.463
4ezl0SEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
4qa2SHHHistone deacetylase 83.5.1.980.463
4x5iFOLDihydrofolate reductase1.5.1.30.463
5hs1VORLanosterol 14-alpha demethylase/0.463
1iwjCAMCamphor 5-monooxygenase1.14.15.10.462
1t87CAMCamphor 5-monooxygenase1.14.15.10.462
2b365PPEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.462
2m56CAMCamphor 5-monooxygenase1.14.15.10.462
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.462
3g5hYTTMycocyclosin synthase1.14.21.90.462
3tdaPN0Cytochrome P450 2D6/0.462
3w5p4OAVitamin D3 receptor/0.462
3w5tLHPVitamin D3 receptor/0.462
4ajwVWNPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit delta isoform2.7.1.1530.462
4bb3KKAIsopenicillin N synthase1.21.3.10.462
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.462
4g090VDHistidinol dehydrogenase/0.462
4xoqF42Coenzyme F420:L-glutamate ligase/0.462
1culFOKAdenylate cyclase type 2/0.461
1culFOKAdenylate cyclase type 5/0.461
1ju6LYAThymidylate synthase2.1.1.450.461
1m8h6NINitric oxide synthase, inducible1.14.13.390.461
1s0zEB1Vitamin D3 receptor/0.461
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2ojg19AMitogen-activated protein kinase 12.7.11.240.461
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.461
3cv9VDXVitamin D3 dihydroxylase/0.461
3new3NEMitogen-activated protein kinase 14/0.461
3nmvPYVAbscisic acid receptor PYL2/0.461
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.461
4g1y0VOVitamin D3 receptor A/0.461
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.461
4lwwLWWNicotinamide phosphoribosyltransferase2.4.2.120.461
1m9k7NINitric oxide synthase, endothelial1.14.13.390.460
1nooCAHCamphor 5-monooxygenase1.14.15.10.460
1tl1H18Gag-Pol polyprotein2.7.7.490.460
1txiTX5Vitamin D3 receptor/0.460
2punACPMethylthioribose kinase2.7.1.1000.460
3bheBZNGag-Pol polyprotein3.4.23.160.460
3dmtNADGlyceraldehyde-3-phosphate dehydrogenase, glycosomal1.2.1.120.460
3exhTPPPyruvate dehydrogenase E1 component subunit alpha, somatic form, mitochondrial1.2.4.10.460
3exhTPPPyruvate dehydrogenase E1 component subunit beta, mitochondrial1.2.4.10.460
3lu8IQXSerum albumin/0.460
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.460
3w0gW07Vitamin D3 receptor/0.460
4elg52JDihydrofolate reductase/0.460
4g2fC07Ephrin type-A receptor 32.7.10.10.460
4gg50J3Hepatocyte growth factor receptor2.7.10.10.460
4i2pG73Gag-Pol polyprotein2.7.7.490.460
4z9g1Q5Corticotropin-releasing factor receptor 1/0.460
1bk0ACVIsopenicillin N synthase1.21.3.10.459
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
1l2iETCEstrogen receptor/0.459
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1s19MC9Vitamin D3 receptor/0.459
1uyuCAMCamphor 5-monooxygenase1.14.15.10.459
2hamC33Vitamin D3 receptor/0.459
2hb7O1CVitamin D3 receptor/0.459
2o4rVD5Vitamin D3 receptor/0.459
2q9fC3SCholesterol 24-hydroxylase/0.459
2qboCAMCamphor 5-monooxygenase1.14.15.10.459
3fwfCAMCamphor 5-monooxygenase1.14.15.10.459
3qf9NM8Serine/threonine-protein kinase pim-12.7.11.10.459
3u8hBHPPhospholipase A2, membrane associated/0.459
3ue4DB8Tyrosine-protein kinase ABL12.7.10.20.459
4qa0SHHHistone deacetylase 83.5.1.980.459
4r21STRCytochrome P450 family 17 polypeptide 2/0.459
5cp4CAMCamphor 5-monooxygenase1.14.15.10.459
1db48INPhospholipase A2, membrane associated/0.458
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.458
1rd7FOLDihydrofolate reductase1.5.1.30.458
1u72MTXDihydrofolate reductase1.5.1.30.458
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.458
2tscCB3Thymidylate synthase/0.458
3dmjGWEPol protein/0.458
3l08ZIGPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
3vt3VDXVitamin D3 receptor/0.458
3w0jT08Vitamin D3 receptor/0.458
4bfrJ82Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit beta isoform2.7.1.1530.458
4cp4CAMCamphor 5-monooxygenase1.14.15.10.458
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.458
4mv4ACPBiotin carboxylase6.3.4.140.458
4nc3ERM5-hydroxytryptamine receptor 2B/0.458
1fbyREARetinoic acid receptor RXR-alpha/0.457
1iyzNDPProbable quinone oxidoreductase/0.457
1rf9DBRCamphor 5-monooxygenase1.14.15.10.457
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.457
2q7gCCLPyrrolysine--tRNA ligase/0.457
2x7gPVBSRSF protein kinase 22.7.11.10.457
3dr1C5DVitamin D3 receptor A/0.457
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.457
4e37NDPCatalase1.11.1.60.457
4ia2BIVVitamin D3 receptor A/0.457
4rupH97Vitamin D3 receptor A/0.457
2b00GCHPhospholipase A2, major isoenzyme3.1.1.40.456
2vcmM11Isopenicillin N synthase1.21.3.10.456
2zlaVDBVitamin D3 receptor/0.456
3d574HYThyroid hormone receptor beta/0.456
3dauMTXDihydrofolate reductase1.5.1.30.456
3koo24DBifunctional epoxide hydrolase 23.3.2.100.456
3l3rOAGDihydrofolate reductase1.5.1.30.456
3p9tTCLRepressor/0.456
3vtbTKAVitamin D3 receptor/0.456
4awq592Heat shock protein HSP 90-alpha/0.456
4c9pCAMCytochrome P450/0.456
4h4uNDPBiphenyl dioxygenase ferredoxin reductase subunit/0.456
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.456
4iv41GSEstrogen receptor/0.456
4pb25UDNucleoside permease/0.456
4pd6URINucleoside permease/0.456
4rbs0RVMetallo-beta-lactamase type 2/0.456
5dozNDPJamJ/0.456
1dyjDDFDihydrofolate reductase1.5.1.30.455
1kquBR4Phospholipase A2, membrane associated/0.455
1pd9CO4Dihydrofolate reductase1.5.1.30.455
2b36NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
2h42VIAcGMP-specific 3',5'-cyclic phosphodiesterase/0.455
2hc4VDXVitamin D3 receptor A/0.455
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.455
3d3eD3ECorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
3fwjCAMCamphor 5-monooxygenase1.14.15.10.455
3lnbCOAN-acetyltransferase family protein/0.455
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.455
3ua506XCytochrome P450 2B61.14.130.455
3vtdTKDVitamin D3 receptor/0.455
4a2aATPCell division protein FtsA/0.455
4awo99BHeat shock protein HSP 90-alpha/0.455
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.455
4qa1B3NHistone deacetylase 83.5.1.980.455
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.455
4rlh0WEEnoyl-[acyl-carrier-protein] reductase [NADH]/0.455
4uymVOR14-alpha sterol demethylase Cyp51B/0.455
2a1nCAMCamphor 5-monooxygenase1.14.15.10.454
2w2lNADD-mandelate dehydrogenase/0.454
2xvw9NRSerum albumin/0.454
3irxUDRGag-Pol polyprotein2.7.7.490.454
3lakKR1Gag-Pol polyprotein2.7.7.490.454
3mqe416Prostaglandin G/H synthase 21.14.99.10.454
3up3XCAaceDAF-12/0.454
3w0yDS4Vitamin D3 receptor/0.454
4egnTWOCytochrome P450/0.454
4gk2L66Ephrin type-A receptor 32.7.10.10.454
4x5hFOLDihydrofolate reductase1.5.1.30.454
3uzaT4GAdenosine receptor A2a/0.454
1bvrTHTEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.453
1dz8CAMCamphor 5-monooxygenase1.14.15.10.453
1q5dEPBEpothilone C/D epoxidase1.140.453
1yinCM3Estrogen receptor/0.453
2cppCAMCamphor 5-monooxygenase1.14.15.10.453
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.453
2giuFBREstrogen receptor beta/0.453
2qbnCAMCamphor 5-monooxygenase1.14.15.10.453
2zlcVDXVitamin D3 receptor/0.453
3e6oA55Nitric oxide synthase, inducible1.14.13.390.453
3ezpB3NHistone deacetylase 83.5.1.980.453
3fwgCAMCamphor 5-monooxygenase1.14.15.10.453
3is9AC7Gag-Pol polyprotein2.7.7.490.453
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.453
3mdmFJZCholesterol 24-hydroxylase/0.453
3negPYVAbscisic acid receptor PYL1/0.453
3srqQ19Dihydrofolate reductase1.5.1.30.453
3tdl11DSerum albumin/0.453
3zvuA8SAbscisic acid receptor PYR1/0.453
4bchT7ZCyclin-dependent kinase 92.7.11.220.453
4ge40KEKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
4iw8KN3Estrogen receptor/0.453
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.453
4o761M3Bromodomain-containing protein 4/0.453
6cp4CAMCamphor 5-monooxygenase1.14.15.10.453
1cjcFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.452
1ezfIN0Squalene synthase2.5.1.210.452
1ml6GBXGlutathione S-transferase A22.5.1.180.452
1ot7CHCBile acid receptor/0.452
1p91SAM23S rRNA (guanine(745)-N(1))-methyltransferase/0.452
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.452
1s9qOHTEstrogen-related receptor gamma/0.452
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.452
2ejzSAHDiphthine synthase/0.452
2fr0NDP6-deoxyerythronolide-B synthase EryA1, modules 1 and 2/0.452
2ovmAS0Progesterone receptor/0.452
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.452
2w9sTOPDihydrofolate reductase type 1 from Tn40031.5.1.30.452
2z3uCRRCytochrome P450/0.452
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.452
3mg3ECHOrange carotenoid-binding protein/0.452
3ojiPYVAbscisic acid receptor PYL3/0.452
3zsh469Mitogen-activated protein kinase 14/0.452
4aqc88ATyrosine-protein kinase JAK2/0.452
4bb5HD2Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
4ek1CAMCamphor 5-monooxygenase1.14.15.10.452
4el9AFERibosomal protein S6 kinase alpha-32.7.11.10.452
4enhFVXCholesterol 24-hydroxylase/0.452
4g2h0VQVitamin D3 receptor A/0.452
4g3jVNTLanosterol 14-alpha-demethylase/0.452
4lgaA2OAbscisic acid receptor PYL2/0.452
4nb6444Nuclear receptor ROR-gamma/0.452
5eccNAPDehydrofolate reductase type I/0.452
1drbMTXDihydrofolate reductase1.5.1.30.451
1qknRALEstrogen receptor beta/0.451
1t86CAMCamphor 5-monooxygenase1.14.15.10.451
1zky689Estrogen receptor/0.451
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.451
2iviACWIsopenicillin N synthase1.21.3.10.451
2qocANPEphrin type-A receptor 32.7.10.10.451
2wi72KLHeat shock protein HSP 90-alpha/0.451
3ansS38Bifunctional epoxide hydrolase 23.3.2.100.451
3g4iD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.451
3h3r14HCollagen type IV alpha-3-binding protein/0.451
3kpzZNEVitamin D3 receptor/0.451
3ntz3TZDihydrofolate reductase1.5.1.30.451
3qzyFADFAD-linked sulfhydryl oxidase/0.451
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.451
4c9oCAMCytochrome P450/0.451
4dscA8SAbscisic acid receptor PYL3/0.451
4dtk7LISerine/threonine-protein kinase pim-12.7.11.10.451
4fa60TAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4fhh0U3Vitamin D3 receptor A/0.451
4fhi0S4Vitamin D3 receptor A/0.451
4i13FOLDihydrofolate reductase1.5.1.30.451
4x5jFOLDihydrofolate reductase1.5.1.30.451
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.451
5akk1P8Bifunctional epoxide hydrolase 23.1.3.760.451
1fduESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1jpaANPEphrin type-B receptor 22.7.10.10.450
1s3vTQDDihydrofolate reductase1.5.1.30.450
1synF89Thymidylate synthase/0.450
1tvrTB9Gag-Pol polyprotein2.7.7.490.450
1yc2NADNAD-dependent protein deacylase 2/0.450
2aclREARetinoic acid receptor RXR-alpha/0.450
2dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.450
2iyaZIOOleandomycin glycosyltransferase/0.450
2uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.450
2zl9VDAVitamin D3 receptor/0.450
3cquCQURAC-alpha serine/threonine-protein kinase2.7.11.10.450
3inxJZCHeat shock protein HSP 90-alpha/0.450
3nefPYVAbscisic acid receptor PYL1/0.450
3td8D2RDihydrofolate reductase1.5.1.30.450
4cztCPSCBL-interacting serine/threonine-protein kinase 232.7.11.10.450
4e0u0MVCyclic dipeptide N-prenyltransferase/0.450
4f1mACPProbable serine/threonine-protein kinase roco42.7.11.10.450
4i6h1C8Serine/threonine-protein kinase PLK22.7.11.210.450
4ict1EDMycocyclosin synthase1.14.21.90.450
4jvmXDIEstrogen sulfotransferase2.8.2.40.450
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.450
4k6i9RARetinoic acid receptor RXR-alpha/0.450
4l8u9AZSerum albumin/0.450
4rw4494Gag-Pol polyprotein2.7.7.490.450
1cqp803Integrin alpha-L/0.449
1dhjMTXDihydrofolate reductase1.5.1.30.449
1g2vTTPGlucose-1-phosphate thymidylyltransferase/0.449
1oc1ASVIsopenicillin N synthase1.21.3.10.449
1rk3VDXVitamin D3 receptor/0.449
2fai459Estrogen receptor/0.449
2qo9ANPEphrin type-A receptor 32.7.10.10.449
2xvv9DNSerum albumin/0.449
3bgqVX2Serine/threonine-protein kinase pim-12.7.11.10.449
3byzH11Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
3gw9VNILanosterol 14-alpha-demethylase/0.449
3gwfNAPCyclohexanone monooxygenase/0.449
3gxoMQAMitomycin biosynthesis 6-O-methyltransferase/0.449
3r02UNMSerine/threonine-protein kinase pim-12.7.11.10.449
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.449
4m7vRARDihydrofolate reductase/0.449
4pkl1GHUncharacterized protein/0.449
4u0oMTALipoyl synthase 2/0.449
4zowCLMMultidrug transporter MdfA/0.449
1bwsNDPGDP-L-fucose synthase/0.448
1hb3SCVIsopenicillin N synthase1.21.3.10.448
1jt6DEQHTH-type transcriptional regulator QacR/0.448
1kijNOVDNA gyrase subunit B/0.448
1lhvNOGSex hormone-binding globulin/0.448
1pkfEPDEpothilone C/D epoxidase1.140.448
1revTB9Gag-Pol polyprotein2.7.7.490.448
1tl7FOKAdenylate cyclase type 2/0.448
1tl7FOKAdenylate cyclase type 5/0.448
1uy7PU4Heat shock protein HSP 90-alpha/0.448
1vzdCB3Thymidylate synthase/0.448
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.448
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.448
2cy0NAPShikimate dehydrogenase (NADP(+))/0.448
2fgkATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2pulACPMethylthioribose kinase2.7.1.1000.448
2vtdLKMUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.448
3bfa9ODOdorant binding protein ASP1/0.448
3fkoFKOMitogen-activated protein kinase 14/0.448
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.448
3ml9ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.448
3w0hW12Vitamin D3 receptor/0.448
3we45FIRibosomal protein S6 kinase beta-12.7.11.10.448
3zhqTPPMultifunctional 2-oxoglutarate metabolism enzyme1.2.4.20.448
4ap1NAPSteroid monooxygenase/0.448
4at2ASDPossible succinate dehydrogenase/0.448
4bquCLRJapanin/0.448
4efuEFUHeat shock protein HSP 90-alpha/0.448
4ezj0SCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4fz60VGTyrosine-protein kinase SYK2.7.10.20.448
4i0t1B6Tyrosine-protein kinase SYK2.7.10.20.448
4jlt8PRCytochrome P450 2B41.14.14.10.448
4k9v6AWCytochrome P450 3A4/0.448
4rujVDXVitamin D3 receptor A/0.448
4tzk641Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.448
4ubsDIFPentalenic acid synthase1.14.15.110.448
1dnaCB3Thymidylate synthase/0.447
1e6eFADNADPH:adrenodoxin oxidoreductase, mitochondrial1.18.1.60.447
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.447
1ly3COGDihydrofolate reductase1.5.1.30.447
1n4hREANuclear receptor ROR-beta/0.447
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
1rt5UC2Gag-Pol polyprotein2.7.7.490.447
1s9pDESEstrogen-related receptor gamma/0.447
1umlFR4Adenosine deaminase3.5.4.40.447
2cd8PXICytochrome P450 monooxygenase PikC/0.447
2mm3CHOGastrotropin/0.447
2oaxSNLMineralocorticoid receptor/0.447
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2w4qCBWProstaglandin reductase 21.3.1.480.447
3cehAVEGlycogen phosphorylase, liver form2.4.1.10.447
3fy8XCFDihydrofolate reductase1.5.1.30.447
3h3t16HCollagen type IV alpha-3-binding protein/0.447
3m8qDJZGag-Pol polyprotein2.7.7.490.447
3njoP2MAbscisic acid receptor PYR1/0.447
3rukAERSteroid 17-alpha-hydroxylase/17,20 lyase/0.447
4a51DQ8Kinesin-like protein KIF11/0.447
4a7cE46Serine/threonine-protein kinase pim-12.7.11.10.447
4dsbA8SAbscisic acid receptor PYL3/0.447
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.447
4hnc0UTMandelate racemase/0.447
4iae1DXAlr2278 protein/0.447
4ifvT27Gag-Pol polyprotein2.7.7.490.447
4iui1GQEstrogen receptor/0.447
4j97ACPFibroblast growth factor receptor 2/0.447
4lg5A1OAbscisic acid receptor PYL2/0.447
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.447
4p6xHCYGlucocorticoid receptor/0.447
4xe606UDihydrofolate reductase1.5.1.30.447
3reyXACAdenosine receptor A2a/0.447
1dz4CAMCamphor 5-monooxygenase1.14.15.10.446
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1ie9VDXVitamin D3 receptor/0.446
1jlcFTCGag-Pol polyprotein2.7.7.490.446
1k6tXN1Gag-Pol polyprotein3.4.23.160.446
1pp9SMACytochrome b/0.446
1vruAAPGag-Pol polyprotein2.7.7.490.446
1yqj6NPMitogen-activated protein kinase 14/0.446
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.446
2aq8NAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.446
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.446
2jn3JN3Fatty acid-binding protein, liver/0.446
2pmdGNPTranslation initiation factor 2 subunit gamma/0.446
2w6nOA2Biotin carboxylase6.3.4.140.446
2x9dITCTetracycline repressor protein class D/0.446
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.446
3dt1P40Mitogen-activated protein kinase 14/0.446
3fnu006HAP protein/0.446
3inwJZBHeat shock protein HSP 90-alpha/0.446
3ituIBMcGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
3lamKRPGag-Pol polyprotein2.7.7.490.446
3mtfA3FActivin receptor type-12.7.11.300.446
3v94WYQPhosphodiesterase/0.446
3w0iO11Vitamin D3 receptor/0.446
3w5q3KLVitamin D3 receptor/0.446
3zkuHCVIsopenicillin N synthase1.21.3.10.446
4c1iEH9cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4l4bCAMCamphor 5-monooxygenase1.14.15.10.446
4l9q9TPSerum albumin/0.446
4mr61K0Bromodomain-containing protein 2/0.446
5c6cCMPcGMP-dependent protein kinase 22.7.11.120.446
1ej2NADNicotinamide-nucleotide adenylyltransferase2.7.7.10.445
1olmVTQSEC14-like protein 2/0.445
1r9oFLPCytochrome P450 2C9/0.445
1uomPTIEstrogen receptor/0.445
1wwkNAD307aa long hypothetical phosphoglycerate dehydrogenase/0.445
1x7e244Estrogen receptor/0.445
1x8vESLLanosterol 14-alpha demethylase1.14.13.700.445
1ykdCMPAdenylate cyclase/0.445
1zg32HIIsoflavone 4'-O-methyltransferase/0.445
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.445
2b0m201Dihydroorotate dehydrogenase (quinone), mitochondrial1.3.5.20.445
2bj4OHTEstrogen receptor/0.445
2bu9HFVIsopenicillin N synthase1.21.3.10.445
3datMTXDihydrofolate reductase/0.445
3kdiA8SAbscisic acid receptor PYL2/0.445
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3nglNAPBifunctional protein FolD/0.445
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
3zoiM2WIsopenicillin N synthase1.21.3.10.445
4awp99AHeat shock protein HSP 90-alpha/0.445
4bwaN0BPyrrolysine--tRNA ligase/0.445
4g2l0WLHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.445
4tv3ML9Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform/0.445
4u7wNDPMxaA/0.445
1a27ESTEstradiol 17-beta-dehydrogenase 11.1.1.620.444
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
1cjuFOKAdenylate cyclase type 2/0.444
1cjuFOKAdenylate cyclase type 5/0.444
1eetBFUGag-Pol polyprotein2.7.7.490.444
1lsoNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.444
1q6s214Tyrosine-protein phosphatase non-receptor type 13.1.3.480.444
1q9mROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.444
1upbTPPN(2)-(2-carboxyethyl)arginine synthase/0.444
2b378PSEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
2cdaNAPGlucose 1-dehydrogenase/0.444
2fszOHTEstrogen receptor beta/0.444
2l98STLTroponin C, slow skeletal and cardiac muscles/0.444
2oxtSAMGenome polyprotein/0.444
2qe4JJ3Estrogen receptor/0.444
2rabNADGlutathione amide reductase/0.444
2rqfJH3Hemolymph juvenile hormone binding protein/0.444
2vn1FK5Peptidylprolyl isomerase/0.444
2ykcYKCHeat shock protein HSP 90-alpha/0.444
3dhoB2MStreptogramin A acetyltransferase2.3.10.444
3e7iB2Nitric oxide synthase, inducible1.14.13.390.444
3fzr3JZProtein-tyrosine kinase 2-beta2.7.10.20.444
3mjrAC2Deoxycytidine kinase2.7.1.740.444
3rbqGLY_ALA_GLY_ALA_DAOProtein unc-119 homolog A/0.444
3zraORBProgesterone receptor/0.444
4b7sQLECytochrome P450 monooxygenase PikC/0.444
4bmpFMNProtein NrdI/0.444
4boeCLRJapanin/0.444
4c3yANB3-ketosteroid dehydrogenase/0.444
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.444
4eoi1ROCyclin-dependent kinase 22.7.11.220.444
4fgh0U6Dihydrofolate reductase1.5.1.30.444
4jvb1M0Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4kkyCAMCamphor 5-monooxygenase1.14.15.10.444
4yswNAIXanthine dehydrogenase/oxidase/0.444
5d1bTSNHistone deacetylase 83.5.1.980.444
1blzACVIsopenicillin N synthase1.21.3.10.443
1diuBDMDihydrofolate reductase1.5.1.30.443
1enzNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
1jioDEB6-deoxyerythronolide B hydroxylase/0.443
1nceCB3Thymidylate synthase/0.443
1uhlMEIRetinoic acid receptor RXR-beta/0.443
1uofPNNDeacetoxycephalosporin C synthase1.14.20.10.443
1zzlTZYMitogen-activated protein kinase 14/0.443
2g44T3OEstrogen receptor/0.443
2y30SM8Putative repressor SimReg2/0.443
3bgrT27Gag-Pol polyprotein2.7.7.490.443
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.443
3fraI2HDihydrofolate reductase1.5.1.30.443
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.443
3jw3TOPDihydrofolate reductase/0.443
3l0lHC3Nuclear receptor ROR-gamma/0.443
3pm1ETHTH-type transcriptional regulator QacR/0.443
3pxkPXKFocal adhesion kinase 12.7.10.20.443
3t3q9PLCytochrome P450 2A61.14.130.443
3uagUMAUDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.443
3uvvREARetinoic acid receptor RXR-alpha/0.443
3zkyWT4Isopenicillin N synthase1.21.3.10.443
4bcqTJFCyclin-dependent kinase 22.7.11.220.443
4geb0LDKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.443
4gk4L90Ephrin type-A receptor 32.7.10.10.443
4guvFADTetX family tetracycline inactivation enzyme/0.443
4h4o506Gag-Pol polyprotein2.7.7.490.443
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.443
4ips1G4Mycocyclosin synthase1.14.21.90.443
4iyg1HUStrictosidine synthase4.3.3.20.443
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.443
4ma628EAra h 8 allergen/0.443
4o2bLOCTubulin beta-2B chain/0.443
4rraA3TProbable threonine--tRNA ligase 26.1.1.30.443
5c1mCLRMu-type opioid receptor/0.443
1dgfNDPCatalase1.11.1.60.442
1dlrMXADihydrofolate reductase1.5.1.30.442
1hniAAAGag-Pol polyprotein2.7.7.490.442
1krv147Galactoside O-acetyltransferase2.3.1.180.442
1osvCHCBile acid receptor/0.442
1ove358Mitogen-activated protein kinase 14/0.442
1qxlFR8Adenosine deaminase3.5.4.40.442
1s7gNADNAD-dependent protein deacylase 2/0.442
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.442
1t47NTD4-hydroxyphenylpyruvate dioxygenase1.13.11.270.442
2cx8SAHRibosomal RNA small subunit methyltransferase E/0.442
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.442
3g8eIS1Nicotinamide phosphoribosyltransferase2.4.2.120.442
3o0iP54Heat shock protein HSP 90-alpha/0.442
3opdHIEHeat shock protein 83/0.442
3sr5Q12Dihydrofolate reductase1.5.1.30.442
3zep1NXTyrosine-protein kinase JAK32.7.10.20.442
3zk5Z18Cytochrome P450 monooxygenase PikC/0.442
4deg0JJHepatocyte growth factor receptor2.7.10.10.442
4fweFADLysine-specific histone demethylase 1B10.442
4jqh1MFAlr2278 protein/0.442
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.442
4lt63ATPoly(A) polymerase gamma2.7.7.190.442
4q71FADBifunctional protein PutA/0.442
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.442
4ruoBIVVitamin D3 receptor A/0.442
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.442
5dx3ESTEstrogen receptor/0.442
6prcCEBReaction center protein L chain/0.442
1b2lNDCAlcohol dehydrogenase1.1.1.10.441
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.441
1nq24HYThyroid hormone receptor beta/0.441
1q13TESProstaglandin-E(2) 9-reductase1.1.1.1890.441
1rf7DHFDihydrofolate reductase1.5.1.30.441
1t13INI6,7-dimethyl-8-ribityllumazine synthase 2/0.441
1yhsSTUSerine/threonine-protein kinase pim-12.7.11.10.441
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.441
2bikBI1Serine/threonine-protein kinase pim-12.7.11.10.441
2ibzUQ6Cytochrome b/0.441
2o4jVD4Vitamin D3 receptor/0.441
2ovhAS0Progesterone receptor/0.441
2pogWSTEstrogen receptor/0.441
2puiADPMethylthioribose kinase2.7.1.1000.441
2qk8MTXDihydrofolate reductase/0.441
2rkvZBATrichothecene 3-O-acetyltransferase/0.441
2tpsTPSThiamine-phosphate synthase/0.441
2vg7NNIGag-Pol polyprotein2.7.7.490.441
2wkmPFYHepatocyte growth factor receptor2.7.10.10.441
2ykeYKEHeat shock protein HSP 90-alpha/0.441
2zzaFOLDihydrofolate reductase/0.441
3b9lAZZSerum albumin/0.441
3d78NBBPheromone-binding protein ASP1/0.441
3t14FADSulfide-quinone reductase/0.441
3t3r9PLCytochrome P450 2A61.14.130.441
4d7eFADPutative lysine-N-oxygenase/0.441
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.441
4iv21GREstrogen receptor/0.441
4ivd15TTyrosine-protein kinase JAK1/0.441
4j6i1JVPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4jvnYUGEstrogen sulfotransferase2.8.2.40.441
4nm9FADBifunctional protein PutA/0.441
4nmbFADBifunctional protein PutA/0.441
4qe6JN3Bile acid receptor/0.441
4zasTYDCalS13/0.441
5cyqT27Gag-Pol polyprotein2.7.7.490.441
1dajMOTDihydrofolate reductase1.5.1.30.440
1gufNDPEnoyl-[acyl-carrier-protein] reductase 1, mitochondrial1.3.1.100.440
1gwrESTEstrogen receptor/0.440
1o5rFR9Adenosine deaminase3.5.4.40.440
1o76CAMCamphor 5-monooxygenase1.14.15.10.440
1p7tACOMalate synthase G/0.440
1rdtL79Retinoic acid receptor RXR-alpha/0.440
1uyePU9Heat shock protein HSP 90-alpha/0.440
2ev9NAPShikimate dehydrogenase (NADP(+))/0.440
2izt23DCasein kinase I isoform gamma-32.7.11.10.440
2qg2A91Heat shock protein HSP 90-alpha/0.440
2uxpCLMHTH-type transcriptional regulator TtgR/0.440
2wpxACOOrf14/0.440
2wueKEK4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase3.7.1.170.440
3d8vUD1Bifunctional protein GlmU/0.440
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.440
3ibeL64Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.440
3jzfJZKBiotin carboxylase6.3.4.140.440
3lfeZ84Mitogen-activated protein kinase 14/0.440
3pd2A3SThreonine--tRNA ligase6.1.1.30.440
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
3v1yNADGlyceraldehyde-3-phosphate dehydrogenase 1, cytosolic1.2.1.120.440
3vg9ZMAAdenosine receptor A2a/0.440
3w0aDS5Vitamin D3 receptor/0.440
3zbnCOA3-ketoacyl-CoA thiolase-like protein/0.440
3zr7OR8Progesterone receptor/0.440
4anv751Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.440
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.440
4ib4ERM5-hydroxytryptamine receptor 2B/0.440
4ig3T27Gag-Pol polyprotein2.7.7.490.440
4lsjLSJGlucocorticoid receptor/0.440
4ltsLTSNicotinamide phosphoribosyltransferase2.4.2.120.440
4pd5GEONucleoside permease/0.440
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
5bn4ANPV-type ATP synthase alpha chain/0.440
5dr6SKEAurora kinase A2.7.11.10.440