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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1esqTZPHydroxyethylthiazole kinase

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1esqTZPHydroxyethylthiazole kinase/1.000
3isjA8DPantothenate synthetase6.3.2.10.518
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.517
3u9eCOALmo1369 protein/0.513
2rh9IGPTryptophan synthase alpha chain/0.509
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.509
3bhtMFRCyclin-dependent kinase 22.7.11.220.507
1kfbIGPTryptophan synthase alpha chain/0.503
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.502
1aztGSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.500
3e8eG98cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.499
3ivgFG5Pantothenate synthetase6.3.2.10.494
4xr9NADCalS8/0.494
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.493
4zj8SUVOrexin receptor type 1/0.493
4yqfGDPSeptin-9/0.490
1qoqIGPTryptophan synthase alpha chain/0.489
3lxiCAMCytochrome P450/0.489
4iqlFMNEnoyl-(Acyl-carrier-protein) reductase II/0.488
2a1mCAMCamphor 5-monooxygenase1.14.15.10.486
2bn4FMNNADPH--cytochrome P450 reductase/0.486
4ck2NVUIntegrase/0.486
4ddhMS0Pantothenate synthetase6.3.2.10.486
4y3jHICEndothiapepsin3.4.23.220.486
1looGTPAdenylosuccinate synthetase isozyme 1/0.485
2pz8APCNH(3)-dependent NAD(+) synthetase/0.485
1f52ADPGlutamine synthetase6.3.1.20.484
1omoNADAlanine dehydrogenase/0.484
3i12ADPD-alanine--D-alanine ligase A6.3.2.40.484
1rfvADPPyridoxal kinase2.7.1.350.483
2fznFADBifunctional protein PutA1.5.5.20.483
2oc4IMHPurine nucleoside phosphorylase2.4.2.10.483
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.482
3rbaCODPhosphopantetheine adenylyltransferase/0.482
2a1y5GPGMP reductase/0.480
2wpa889Cyclin-dependent kinase 22.7.11.220.480
3t6iNC9Endothiapepsin3.4.23.220.480
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.479
1p4aPCPPur operon repressor/0.478
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.478
3tneRITCandidapepsin-13.4.23.240.478
4jxxATPGlutamine--tRNA ligase6.1.1.180.478
4l4eCAMCamphor 5-monooxygenase1.14.15.10.478
3imeBZ2Pantothenate synthetase6.3.2.10.477
3t7qRB4Endothiapepsin3.4.23.220.477
4dtbGMPAPH(2'')-Id/0.477
4g74FADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.477
4l4fCAMCamphor 5-monooxygenase1.14.15.10.477
4la7A1OAbscisic acid receptor PYL2/0.477
2webPP4Penicillopepsin-13.4.23.200.476
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.476
3psyRB9Endothiapepsin3.4.23.220.476
4l7j1W2Beta-secretase 13.4.23.460.476
4y380A9Endothiapepsin3.4.23.220.476
4y45F91Endothiapepsin3.4.23.220.476
5cyoGDPSeptin-9/0.476
1t88CAMCamphor 5-monooxygenase1.14.15.10.475
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.475
2pv7NADT-protein1.3.1.120.475
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.475
4h1e10JBeta-secretase 13.4.23.460.475
4jx1CAMCamphor 5-monooxygenase1.14.15.10.475
4mv8ACPBiotin carboxylase6.3.4.140.475
4zeaIMIEndothiapepsin3.4.23.220.475
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.474
2z1mNDPGDP-mannose 4,6-dehydratase/0.474
4fxy0W2Neurolysin, mitochondrial3.4.24.160.474
4jx1CAHCamphor 5-monooxygenase1.14.15.10.474
5ero210Fusicoccadiene synthase2.5.1.290.474
1n77ATPGlutamate--tRNA ligase6.1.1.170.473
1o9bNAIQuinate/shikimate dehydrogenase/0.473
2dvlFADAcyl-CoA dehydrogenase/0.473
3hllI45Mitogen-activated protein kinase 14/0.473
1u2yGOXPancreatic alpha-amylase/0.472
1u33LM2Pancreatic alpha-amylase/0.472
4de50JDPantothenate synthetase6.3.2.10.472
4y3qF02Endothiapepsin3.4.23.220.472
1ezvUQ6Cytochrome b/0.471
1xvaSAMGlycine N-methyltransferase2.1.1.200.471
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.471
2yy8MTAtRNA (cytidine(56)-2'-O)-methyltransferase/0.471
3lb8FADPutidaredoxin reductase1.18.1.50.471
4kkyCAMCamphor 5-monooxygenase1.14.15.10.471
4lez1SYCyclic GMP-AMP synthase/0.471
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.470
1mhtSAHModification methylase HhaI2.1.1.370.470
2oapANPType II secretion system protein (GspE-2)/0.470
2wxvWXVCyclin-dependent kinase 22.7.11.220.470
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.470
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.470
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.470
4frkDWDBeta-secretase 13.4.23.460.470
4rdiATPtRNA threonylcarbamoyladenosine dehydratase6.10.470
5agaANPDNA polymerase theta/0.470
1k6vXN2Gag-Pol polyprotein3.4.23.160.469
1kfcIPLTryptophan synthase alpha chain/0.469
1knrFADL-aspartate oxidase1.4.3.160.469
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
3coy53HPantothenate synthetase6.3.2.10.469
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.469
3tb9CDPRibonucleoside-diphosphate reductase large chain 11.17.4.10.469
4y4jLNREndothiapepsin3.4.23.220.469
1k6pXN3Gag-Pol polyprotein3.4.23.160.468
2bf4FMNNADPH--cytochrome P450 reductase/0.468
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.468
3imgBZ2Pantothenate synthetase6.3.2.10.468
3r9uFADThioredoxin reductase/0.468
1foaUD1Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase2.4.1.1010.467
1p9wANPType II secretion system protein E/0.467
1yrdCAMCamphor 5-monooxygenase1.14.15.10.467
2rhgIGPTryptophan synthase alpha chain/0.467
2x3fAPCPantothenate synthetase/0.467
3pi0F91Endothiapepsin3.4.23.220.467
3zksWZVBeta-secretase 23.4.23.450.467
4dptAGSMevalonate diphosphate decarboxylase/0.467
4dtaADNAPH(2'')-Id/0.467
1bw9NADPhenylalanine dehydrogenase/0.466
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.466
3dm5GDPSignal recognition particle 54 kDa protein/0.466
3juqAJDPhenazine biosynthesis protein A/B/0.466
4yaoFMNNADPH--cytochrome P450 reductase/0.466
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.466
1n2hPAJPantothenate synthetase6.3.2.10.465
1n2jPAFPantothenate synthetase6.3.2.10.465
2a1nCAMCamphor 5-monooxygenase1.14.15.10.465
2qs4LY5Glutamate receptor ionotropic, kainate 1/0.465
3ibqATPPyridoxal kinase/0.465
3s7dLEU_SER_LYS_LYS_MLZN-lysine methyltransferase SMYD2/0.465
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.465
4eb7PLPCysteine desulfurase IscS 2/0.465
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.465
1dliUDXUDP-glucose 6-dehydrogenase/0.464
1dljUGAUDP-glucose 6-dehydrogenase/0.464
1k6tXN1Gag-Pol polyprotein3.4.23.160.464
1lnyIMOAdenylosuccinate synthetase isozyme 1/0.464
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.464
2b53D23Cyclin-dependent kinase 22.7.11.220.464
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.464
2ea2F77Methionine aminopeptidase 2/0.464
3fwjCAMCamphor 5-monooxygenase1.14.15.10.464
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.464
4fv8E63Mitogen-activated protein kinase 12.7.11.240.464
4djhJDCKappa-type opioid receptor/0.464
1g1aNADdTDP-glucose 4,6-dehydratase/0.463
1ijjLARActin, alpha skeletal muscle/0.463
1vi2NADQuinate/shikimate dehydrogenase/0.463
2hutSAHDiphthine synthase/0.463
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.463
2ylxFADPhenylacetone monooxygenase1.14.13.920.463
3junAKDPhenazine biosynthesis protein A/B/0.463
3lm9ADPPutative fructokinase2.7.1.40.463
3wrlCAMCamphor 5-monooxygenase1.14.15.10.463
4fryNADPutative signal-transduction protein with CBS domains/0.463
4qq3XMPInosine-5'-monophosphate dehydrogenase/0.463
1qvrANPChaperone protein ClpB/0.462
1svlADPLarge T antigen3.6.40.462
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.462
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.462
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.462
2v58LZJBiotin carboxylase6.3.4.140.462
2vtbFADCryptochrome DASH, chloroplastic/mitochondrial/0.462
2yj4ATPCopper-transporting ATPase/0.462
3iobA4DPantothenate synthetase6.3.2.10.462
3ivxFG6Pantothenate synthetase6.3.2.10.462
3nbwTR4Ketohexokinase/0.462
4b1uLABActin, alpha skeletal muscle/0.462
4f9b0SYCell division cycle 7-related protein kinase2.7.11.10.462
1ja0FMNNADPH--cytochrome P450 reductase/0.461
1o94ADPTrimethylamine dehydrogenase1.5.8.20.461
1phhFADp-hydroxybenzoate hydroxylase/0.461
1zgyBRLPeroxisome proliferator-activated receptor gamma/0.461
2a7r5GPGMP reductase 2/0.461
2c1aI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.461
2ccu2D9Heat shock protein HSP 90-alpha/0.461
2cppCAMCamphor 5-monooxygenase1.14.15.10.461
2e91ZOLGeranylgeranyl pyrophosphate synthase/0.461
3iocA5DPantothenate synthetase6.3.2.10.461
3k1wBFXRenin3.4.23.150.461
4ambDUDPutative glycosyl transferase/0.461
4h3j10WBeta-secretase 13.4.23.460.461
5f8eSAHPossible transcriptional regulatory protein/0.461
1zp4FAD5,10-methylenetetrahydrofolate reductase1.5.1.200.460
2a94AP0L-lactate dehydrogenase1.1.1.270.460
2i51FMNPyridoxamine 5'-phosphate oxidase-related, FMN-binding/0.460
2ibzUQ6Cytochrome b/0.460
2j9gANPBiotin carboxylase6.3.4.140.460
2qboCAMCamphor 5-monooxygenase1.14.15.10.460
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.460
2rkgAB1Pol protein/0.460
2v00V15Endothiapepsin3.4.23.220.460
2wedPP6Penicillopepsin-13.4.23.200.460
2zjwREFCasein kinase II subunit alpha2.7.11.10.460
3cltFADElectron transfer flavoprotein subunit alpha/0.460
3vswR31Renin3.4.23.150.460
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.460
4ypuSAMHistone-lysine N-methyltransferase ASH1L2.1.1.430.460
1drtPCVClavaminate synthase 11.14.11.210.459
1u30GOXPancreatic alpha-amylase/0.459
1u3cFADCryptochrome-1/0.459
1u3dFADCryptochrome-1/0.459
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.459
2p3b3TLV-1 PROTEASE protein/0.459
2p3b3TLV-1 protease/0.459
3fwgCAMCamphor 5-monooxygenase1.14.15.10.459
3qizQI2Botulinum neurotoxin type A3.4.24.690.459
4dju0KKBeta-secretase 13.4.23.460.459
1t86CAMCamphor 5-monooxygenase1.14.15.10.458
1t87CAMCamphor 5-monooxygenase1.14.15.10.458
2ephASP_TRP_ASNFructose-bisphosphate aldolase4.1.2.130.458
2jdtI5ScAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.458
3b1dPLSBetaC-S lyase/0.458
3fwfCAMCamphor 5-monooxygenase1.14.15.10.458
3qfrFMNNADPH--cytochrome P450 reductase/0.458
3udq09EBeta-secretase 13.4.23.460.458
4m9aFDAAcyl-CoA dehydrogenase/0.458
1w4xFADPhenylacetone monooxygenase1.14.13.920.457
1yrcCAMCamphor 5-monooxygenase1.14.15.10.457
2db3ANPATP-dependent RNA helicase vasa, isoform A3.6.4.130.457
2fs4PZ1Renin3.4.23.150.457
2vf3GVS4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.457
2yj5ATPCopper-transporting ATPase/0.457
2z95NDPGDP-mannose 4,6-dehydratase/0.457
3c35KAIGlutamate receptor ionotropic, kainate 1/0.457
3drcMTXDihydrofolate reductase1.5.1.30.457
3ivcFG4Pantothenate synthetase6.3.2.10.457
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.457
3q9lATPSeptum site-determining protein MinD/0.457
3s6gCOAN-acetylglutamate kinase / N-acetylglutamate synthase/0.457
3uk6ADPRuvB-like 23.6.4.120.457
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.457
4h3i10VBeta-secretase 13.4.23.460.457
5hg0SAMPantothenate synthetase/0.457
1dj2GDPAdenylosuccinate synthetase, chloroplastic/0.456
1g41ADPATP-dependent protease ATPase subunit HslU/0.456
1k6cMK1Gag-Pol polyprotein3.4.23.160.456
1odx0E8Gag-Pol polyprotein3.4.23.160.456
1rp7TZDPyruvate dehydrogenase E1 component1.2.4.10.456
1u1iNADMyo-inositol-1-phosphate synthase (Ino1)/0.456
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.456
2q46NAPUncharacterized protein At5g02240/0.456
2v5aLZLBiotin carboxylase6.3.4.140.456
2yyuC5POrotidine 5'-phosphate decarboxylase/0.456
3dzvADPHydroxyethylthiazole kinase/0.456
3oqfS51Renin3.4.23.150.456
3qt62P0Mevalonate diphosphate decarboxylase/0.456
3wrmCAMCamphor 5-monooxygenase1.14.15.10.456
4a4zANPAntiviral helicase SKI23.6.4.130.456
4b78KGGBeta-secretase 13.4.23.460.456
4dpuAGSMevalonate diphosphate decarboxylase/0.456
4h3g10QBeta-secretase 13.4.23.460.456
4xvuATPATPase GET3/0.456
4xz3COAAcyl-CoA synthetase (NDP forming)/0.456
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.456
4z54GDPNeuronal-specific septin-3/0.456
1dz8CAMCamphor 5-monooxygenase1.14.15.10.455
1fpyADPGlutamine synthetase6.3.1.20.455
1gtrATPGlutamine--tRNA ligase6.1.1.180.455
1w2xRCPAcetyl-CoA carboxylase/0.455
1y57MPZProto-oncogene tyrosine-protein kinase Src2.7.10.20.455
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.455
3lnc5GPGuanylate kinase/0.455
3mpt1GKMitogen-activated protein kinase 14/0.455
3nieANPMitogen-activated protein kinase/0.455
3wrjCAMCamphor 5-monooxygenase1.14.15.10.455
5c8yACPTubulin tyrosine ligase/0.455
1dz4CAMCamphor 5-monooxygenase1.14.15.10.454
1nhhANPDNA mismatch repair protein MutL/0.454
1t85CAMCamphor 5-monooxygenase1.14.15.10.454
2bkzSBCCyclin-dependent kinase 22.7.11.220.454
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.454
3ag6PAJPantothenate synthetase/0.454
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3ojxFMNNADPH--cytochrome P450 reductase/0.454
3pwwROCEndothiapepsin3.4.23.220.454
3r7kFDAProbable acyl CoA dehydrogenase/0.454
3vi2HMZOrotidine 5'-monophosphate decarboxylase/0.454
4eueNAITrans-2-enoyl-CoA reductase [NADH]/0.454
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.454
4l4dCAMCamphor 5-monooxygenase1.14.15.10.454
1jdtMTAPurine nucleoside phosphorylase/0.453
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.453
1zgv501Prothrombin3.4.21.50.453
2b56UTPRNA editing complex protein MP57/0.453
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.453
2fy4COACholine O-acetyltransferase2.3.1.60.453
2z6uSAHModification methylase HhaI2.1.1.370.453
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.453
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.453
3f8pNADNADH oxidase/thioredoxin reductase/0.453
3fwiCAMCamphor 5-monooxygenase1.14.15.10.453
3gonANPPhosphomevalonate kinase/0.453
3ioeA7DPantothenate synthetase6.3.2.10.453
3p4tFAOPutative acyl-CoA dehydrogenase/0.453
3rj9NADAlcohol dehydrogenase1.1.1.10.453
3zls92PDual specificity mitogen-activated protein kinase kinase 12.7.12.20.453
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.453
4g3sUD1Bifunctional protein GlmU/0.453
4y9qC2EUncharacterized protein/0.453
5hvnNAD3-dehydroquinate synthase/0.453
1k8y13PTryptophan synthase alpha chain/0.452
1mwmADPPlasmid segregation protein ParM/0.452
1o76CAMCamphor 5-monooxygenase1.14.15.10.452
1rp0AHZThiamine thiazole synthase, chloroplastic/0.452
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.452
2qbmCAMCamphor 5-monooxygenase1.14.15.10.452
2qtaTDPPyruvate dehydrogenase E1 component1.2.4.10.452
2v2zADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.452
2ym8YM8Serine/threonine-protein kinase Chk12.7.11.10.452
3c16GSPGuanine nucleotide-binding protein G(s) subunit alpha isoforms short/0.452
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.452
3fskRO6Mitogen-activated protein kinase 14/0.452
3ingNDPHomoserine dehydrogenase related protein/0.452
3iodA6DPantothenate synthetase6.3.2.10.452
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.452
3lzs017Gag-Pol polyprotein3.4.23.160.452
3wquATPCell division protein FtsA/0.452
4cdmFADDeoxyribodipyrimidine photolyase/0.452
4d03FADPhenylacetone monooxygenase1.14.13.920.452
4tx9AMZPhosphoribosyl isomerase A/0.452
4u7wNDPMxaA/0.452
1e81M91Endothiapepsin3.4.23.220.451
1iwiCAMCamphor 5-monooxygenase1.14.15.10.451
1xagNAD3-dehydroquinate synthase/0.451
2ikuLIYRenin3.4.23.150.451
2v16C47Renin3.4.23.150.451
2wdzNADGalactitol dehydrogenase/0.451
3apwDP0Alpha-1-acid glycoprotein 2/0.451
3h3qH13Collagen type IV alpha-3-binding protein/0.451
3mt817TGlycogen phosphorylase, muscle form2.4.1.10.451
3mx5UTPNucleoprotein/0.451
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.451
3prsRITEndothiapepsin3.4.23.220.451
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.451
4fcwADPChaperone protein ClpB/0.451
4xj43ATCyclic GMP-AMP synthase/0.451
4y57F63Endothiapepsin3.4.23.220.451
1c3eNHRPhosphoribosylglycinamide formyltransferase/0.450
1t2cNAIL-lactate dehydrogenase1.1.1.270.450
2cig1DGDihydrofolate reductase1.5.1.30.450
2dftADPShikimate kinase2.7.1.710.450
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.450
2xyuQ9GEphrin type-A receptor 42.7.10.10.450
3kxw1ZZSaframycin Mx1 synthetase B/0.450
3l63CAMCamphor 5-monooxygenase1.14.15.10.450
3wbbNAPMeso-diaminopimelate D-dehydrogenase/0.450
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.450
4cp4CAMCamphor 5-monooxygenase1.14.15.10.450
4f7iNAD3-isopropylmalate dehydrogenase1.1.1.850.450
4g3pUD1Bifunctional protein GlmU/0.450
5kwvANPPantothenate synthetase/0.450
4z36ON3Lysophosphatidic acid receptor 1/0.450
2cv2GSUGlutamate--tRNA ligase6.1.1.170.449
2ojf4PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.449
2rd2QSIGlutamine--tRNA ligase6.1.1.180.449
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.449
2zaxCAMCamphor 5-monooxygenase1.14.15.10.449
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.449
3t1tGDPProbable gliding protein mglA/0.449
3vyfVYFRenin3.4.23.150.449
4dfg0JVGag-Pol polyprotein3.4.23.160.449
4djw0KPBeta-secretase 13.4.23.460.449
4dt9GMPAPH(2'')-Id/0.449
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.449
4kx6FADFumarate reductase flavoprotein subunit1.3.5.40.449
4n6hEJ4Delta-type opioid receptor/0.449
4nmbFADBifunctional protein PutA/0.449
5cwa0GAAnthranilate synthase component 14.1.3.270.449
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.448
1rdwLARActin, alpha skeletal muscle/0.448
1u28NAPNAD(P) transhydrogenase subunit beta1.6.1.20.448
2ou5FMNPyridoxamine 5'-phosphate oxidase-related FMN-binding protein/0.448
2qbuSAHPrecorrin-2 methyltransferase/0.448
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.448
3a0tADPSensor histidine kinase/0.448
3ai2NDPNADPH-sorbose reductase/0.448
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3ixp834Ecdysone receptor/0.448
3pbzF02Endothiapepsin3.4.23.220.448
3phiNDPShikimate dehydrogenase (NADP(+))/0.448
3vqhIQBcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.448
4a61ANPPlasmid segregation protein ParM/0.448
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.448
5k5zANPUncharacterized protein/0.448
1hmp5GPHypoxanthine-guanine phosphoribosyltransferase2.4.2.80.447
1pjcNADAlanine dehydrogenase/0.447
1qtqQSIGlutamine--tRNA ligase6.1.1.180.447
1tqf32PBeta-secretase 13.4.23.460.447
2f2uM77Rho-associated protein kinase 22.7.11.10.447
2il2LIXRenin3.4.23.150.447
2owkSAHDiphthine synthase/0.447
3ex8AIFRiboflavin biosynthesis protein RibD1.1.1.1930.447
3x2eNAIAdenosylhomocysteinase/0.447
4briUNPEctonucleoside triphosphate diphosphohydrolase I/0.447
4dshFDAUncharacterized protein/0.447
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4g3qUD1Bifunctional protein GlmU/0.447
4imfSI3N-acetylneuraminate lyase/0.447
4nakPBQ2-C-methyl-D-erythritol 4-phosphate cytidylyltransferase, chloroplastic2.7.7.600.447
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.447
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.447
4yryFADGlutamate synthase, beta subunit/0.447
5c3jFADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.447
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.447
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.447
1hbvGANGag-Pol polyprotein/0.446
1nzdUPGDNA beta-glucosyltransferase/0.446
1nzfUPGDNA beta-glucosyltransferase/0.446
1phePIYCamphor 5-monooxygenase1.14.15.10.446
1svmATPLarge T antigen3.6.40.446
1v9aSAHUncharacterized protein/0.446
1zioAP5Adenylate kinase/0.446
2j2pSC2Ficolin-2/0.446
2yi7BZ8Heat shock protein HSP 90-alpha/0.446
3coz54HPantothenate synthetase6.3.2.10.446
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.446
3pcrGTPADP-ribosylation factor 6/0.446
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.446
3vv8B02Beta-secretase 13.4.23.460.446
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.446
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.446
4ivb1J5Tyrosine-protein kinase JAK1/0.446
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.446
4z38FMNMlnA/0.446
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.446
5fv0ONAESX secretion system protein EccC/0.446
1e800GQEndothiapepsin3.4.23.220.445
1i5eU5PUracil phosphoribosyltransferase/0.445
1ivsVAAValine--tRNA ligase6.1.1.90.445
1rfuADPPyridoxal kinase2.7.1.350.445
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.445
2cmoM1LGlutamate receptor 2/0.445
2cv1ATPGlutamate--tRNA ligase6.1.1.170.445
2ien017Gag-Pol polyprotein3.4.23.160.445
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.445
2ylsFADPhenylacetone monooxygenase1.14.13.920.445
2zfaFMNLactate oxidase/0.445
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.445
3em3478Gag-Pol polyprotein3.4.23.160.445
3fwyADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein/0.445
3l5dBDVBeta-secretase 13.4.23.460.445
3oqkS52Renin3.4.23.150.445
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.445
3toh079Gag-Pol polyprotein2.7.7.490.445
4wuoNAD3-isopropylmalate dehydrogenase1.1.1.850.445
1bsvNDPGDP-L-fucose synthase/0.444
1f06NDPMeso-diaminopimelate D-dehydrogenase1.4.1.160.444
1gvv0GMEndothiapepsin3.4.23.220.444
1npdNADQuinate/shikimate dehydrogenase/0.444
1qx4FADNADH-cytochrome b5 reductase 31.6.2.20.444
1tj0FADBifunctional protein PutA1.5.5.20.444
1uyuCAMCamphor 5-monooxygenase1.14.15.10.444
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.444
2i9kSAHModification methylase HhaI2.1.1.370.444
2iiqC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.444
2npxFADNADH peroxidase1.11.1.10.444
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.444
2ylzFADPhenylacetone monooxygenase1.14.13.920.444
3akzGSUGlutamate--tRNA ligase 2/0.444
3cgdFADCoenzyme A disulfide reductase/0.444
3cgeFADCoenzyme A disulfide reductase/0.444
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.444
3le62BZCyclin-dependent kinase 22.7.11.220.444
3nmpPYVAbscisic acid receptor PYL2/0.444
3phjDHKShikimate dehydrogenase (NADP(+))/0.444
3r7wGNPGTP-binding protein GTR2/0.444
3r8lZ30Cyclin-dependent kinase 22.7.11.220.444
3sf6FDAGlutaryl-CoA dehydrogenase/0.444
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.444
4n3cUD1UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.444
4q5jANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
1i9c5ADGlutamate mutase epsilon subunit/0.443
1twwHH2Dihydropteroate synthase/0.443
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.443
2abaSTRPentaerythritol tetranitrate reductase/0.443
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.443
2dxiATPGlutamate--tRNA ligase6.1.1.170.443
2j4dFADCryptochrome DASH, chloroplastic/mitochondrial/0.443
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.443
2jjj0QSEndothiapepsin3.4.23.220.443
2nnqT4BFatty acid-binding protein, adipocyte/0.443
2p20PRXAcetyl-coenzyme A synthetase/0.443
2qfoA51Heat shock protein HSP 90-alpha/0.443
2v2qNVG4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.443
2yr5FADPhenylalanine 2-monooxygenase precursor1.13.12.90.443
2z4y252Geranylgeranyl pyrophosphate synthase/0.443
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.443
3ieuGDPGTPase Era/0.443
3kb1ADPIron-sulfur cluster carrier protein/0.443
3r4b74TGag-Pol polyprotein/0.443
3tjzGNPADP-ribosylation factor 1/0.443
3v5w8PRBeta-adrenergic receptor kinase 12.7.11.150.443
4cf1IY7Integrase/0.443
4gk3L87Ephrin type-A receptor 32.7.10.10.443
4i8zG08Gag-Pol polyprotein3.4.23.160.443
4j531J4Serine/threonine-protein kinase PLK12.7.11.210.443
4n49MGTCap-specific mRNA (nucleoside-2'-O-)-methyltransferase 12.1.1.570.443
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.443
4wucANPDNA gyrase subunit B/0.443
5b0oADPFlagellum-specific ATP synthase3.6.3.140.443
5e7oMD1DMSO reductase family type II enzyme, molybdopterin subunit/0.443
1gebCAMCamphor 5-monooxygenase1.14.15.10.442
1me7MOAInosine-5'-monophosphate dehydrogenase/0.442
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.442
1owpFADDeoxyribodipyrimidine photo-lyase4.1.99.30.442
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.442
2ewvADPTwitching motility protein PilT/0.442
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2fzwNADAlcohol dehydrogenase class-31.1.1.10.442
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.442
2ntrL00Beta-secretase 13.4.23.460.442
2p2qPRXAcetyl-coenzyme A synthetase/0.442
2uw6GVOcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2vynNADGlyceraldehyde-3-phosphate dehydrogenase A/0.442
2wmrZYRSerine/threonine-protein kinase Chk12.7.11.10.442
3clrFADElectron transfer flavoprotein subunit alpha/0.442
3enkUPGUDP-glucose 4-epimerase/0.442
3fr28CAFatty acid-binding protein, adipocyte/0.442
3hk1B64Fatty acid-binding protein, adipocyte/0.442
3p62FMNPentaerythritol tetranitrate reductase/0.442
3ty3GGGHomoisocitrate dehydrogenase1.1.1.870.442
3u8l09QAcetylcholine-binding protein/0.442
3zcsCAWGlycogen phosphorylase, muscle form2.4.1.10.442
4i1nFOLDihydrofolate reductase1.5.1.30.442
4o4iGTPTubulin alpha-1B chain/0.442
4ww0ADPATP-dependent zinc metalloprotease FtsH/0.442
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.442
1bwsNDPGDP-L-fucose synthase/0.441
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.441
1ebuNDAHomoserine dehydrogenase1.1.1.30.441
1ih8APCNH(3)-dependent NAD(+) synthetase6.3.1.50.441
1lbcCYZGlutamate receptor 2/0.441
1nfbNADInosine-5'-monophosphate dehydrogenase 2/0.441
1np7FADCryptochrome DASH/0.441
1s20NAD2,3-diketo-L-gulonate reductase1.1.1.1300.441
1wc4APCAdenylate cyclase/0.441
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.441
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.441
2cftPLPPyridoxal phosphate phosphatase/0.441
2f3mGTDGlutathione S-transferase Mu 12.5.1.180.441
2g37FADProline dehydrogenase/0.441
2hu2NADC-terminal binding protein 1/0.441
2jh0701Prothrombin3.4.21.50.441
3anmSYD1-deoxy-D-xylulose 5-phosphate reductoisomerase1.1.1.2670.441
3djjFADGlutathione reductase, mitochondrial1.8.1.70.441
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3ld6BCDLanosterol 14-alpha demethylase1.14.13.700.441
3lfqA28Cyclin-dependent kinase 22.7.11.220.441
3own3OWRenin3.4.23.150.441
3p5pA3CTaxadiene synthase4.2.3.170.441
3qv1NADGlyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic1.2.1.130.441
3sdkP3NProteasome subunit beta type-53.4.25.10.441
3sdkP3NProteasome subunit beta type-63.4.25.10.441
3skgPB8Beta-secretase 13.4.23.460.441
3t4eNADQuinate/shikimate dehydrogenase/0.441
3ts1TYATyrosine--tRNA ligase6.1.1.10.441
3vg10GTBeta-secretase 13.4.23.460.441
3wb2YGPUncharacterized protein MJ0488/0.441
3wqtANPCell division protein FtsA/0.441
4axaRKDcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
4g9kFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.441
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.441
4jzr4JREgl nine homolog 1/0.441
4k8s1QTBeta-secretase 13.4.23.460.441
4lj8ADPChaperone protein ClpB/0.441
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.441
4opgFDAConserved Archaeal protein/0.441
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.441
4xj3GTPCyclic GMP-AMP synthase/0.441
4yusFMNFamily 3 adenylate cyclase/0.441
4yvz3ATDNA integrity scanning protein DisA/0.441
4z875GPInosine-5'-monophosphate dehydrogenase/0.441
5c1mCLRMu-type opioid receptor/0.441
5c77SAHProtein arginine N-methyltransferase SFM1/0.441
1c1dNAIPhenylalanine dehydrogenase/0.440
1cjtFOKAdenylate cyclase type 2/0.440
1cjtFOKAdenylate cyclase type 5/0.440
1gaxVAAValine--tRNA ligase6.1.1.90.440
1h7wFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.440
1kp3ATPArgininosuccinate synthase6.3.4.50.440
1kqpADJNH(3)-dependent NAD(+) synthetase6.3.1.50.440
1xe55FEPlasmepsin-23.4.23.390.440
1xh6R94cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.440
2cjfRP43-dehydroquinate dehydratase4.2.1.100.440
2fj1CTCTetracycline repressor protein class D/0.440
2flhZEACytokinin-specific binding protein/0.440
2itwITQEpidermal growth factor receptor2.7.10.10.440
2jk6FADTrypanothione reductase/0.440
2nniMTKCytochrome P450 2C8/0.440
2qblCAMCamphor 5-monooxygenase1.14.15.10.440
2woeAR6ADP-ribosyl-[dinitrogen reductase] glycohydrolase3.2.2.240.440
3eldSFGMethyltransferase/0.440
3lfsA07Cyclin-dependent kinase 22.7.11.220.440
3nmhPYVAbscisic acid receptor PYL2/0.440
3nwq2NCGag-Pol polyprotein3.4.23.160.440
3ukfFDAUDP-galactopyranose mutase/0.440
3wrhCAMCamphor 5-monooxygenase1.14.15.10.440
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.440
4dpwAGSMevalonate diphosphate decarboxylase/0.440
4e5pNADPhosphonate dehydrogenase1.20.1.10.440
4frjDWBBeta-secretase 13.4.23.460.440
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.440
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.440
5cypGSPSeptin-9/0.440
5dhhDGWNociceptin receptor/0.440