sc-PDB

List of CHEMBLId :

This value allows a number of roughly comparable measures of half-maximal response concentration/potency/affinity to be compared on a negative logarithmic scale (e.g., an IC50 measurement of 1nM would have a pChEMBL value of 9).

Uniprot Annotation

Name:	Orotidine 5'-monophosphate decarboxylase
ID:	Q8T6J6_PLAFA
AC:	Q8T6J6
Organism:	Plasmodium falciparum
Reign:	Eukaryota
TaxID:	5833
EC Number:	/

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Chains:

Chain Name:	Percentage of Residues within binding site
A	89 %
B	11 %

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Ligand binding site composition:

B-Factor:	50.332
Number of residues:	31
Including
Standard Amino Acids:	28
Non Standard Amino Acids:	0
Water Molecules:	3
Cofactors:
Metals:

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Cavity properties

Ligandability	Volume (Å3)
0.687	597.375

% Hydrophobic	% Polar
48.02	51.98
According to VolSite

HET Code:	HMZ
Formula:	C11H11O5
Molecular weight:	223.202 g/mol
DrugBank ID:	-
Buried Surface Area:	61.21 %
Polar Surface area:	86.66 Å2

Number of
H-Bond Acceptors:	5
H-Bond Donors:	1
Rings:	1
Aromatic rings:	1
Anionic atoms:	1
Cationic atoms:	0
Rule of Five Violation:	0
Rotatable Bonds:	5

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Mass center Coordinates

X	Y	Z
21.479	34.8013	13.5257

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