sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5fkk | TDC | Tetracycline repressor protein class D |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5fkk | TDC | Tetracycline repressor protein class D | / | 1.000 | |
| 4aux | XTC | Tetracycline repressor protein class D | / | 0.614 | |
| 5fkm | TDC | Tetracycline repressor protein class D | / | 0.607 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.598 | |
| 2xpw | OTC | Tetracycline repressor protein class D | / | 0.596 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.588 | |
| 4abz | T1C | Tetracycline repressor protein class D | / | 0.587 | |
| 2o7o | DXT | Tetracycline repressor protein class D | / | 0.585 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.580 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.570 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.569 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.561 | |
| 5fkl | TDC | Tetracycline repressor protein class D | / | 0.557 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.543 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.537 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.536 | |
| 2xb5 | I7T | Tetracycline repressor protein class D | / | 0.527 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.518 | |
| 5dp2 | NAP | CurF | / | 0.504 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.497 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.488 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.485 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.485 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 3mau | PLR | Putative sphingosine-1-phosphate lyase | / | 0.482 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.482 | |
| 2e7r | SAH | Diphthine synthase | / | 0.481 | |
| 4u9z | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.481 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.480 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.480 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.480 | |
| 4tvb | NAD | Homospermidine synthase | 2.5.1.44 | 0.480 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.479 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.479 | |
| 3jyn | NDP | Quinone oxidoreductase | / | 0.479 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.479 | |
| 4rvu | NDP | Probable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein) | / | 0.479 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.479 | |
| 1mcz | RMN | Benzoylformate decarboxylase | 4.1.1.7 | 0.478 | |
| 1ju9 | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.477 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4fam | 0SZ | Aldo-keto reductase family 1 member C3 | / | 0.477 | |
| 1a72 | PAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.476 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.475 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.475 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.475 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.474 | |
| 2ejz | SAH | Diphthine synthase | / | 0.474 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.474 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.474 | |
| 3ms4 | 21N | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.474 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.474 | |
| 1rkh | VD2 | Vitamin D3 receptor | / | 0.473 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.473 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.473 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.473 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.473 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.472 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.471 | |
| 3gob | HXX | DdmC | / | 0.471 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.470 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.470 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.470 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.469 | |
| 1yqx | NAP | Sinapyl alcohol dehydrogenase | / | 0.469 | |
| 2f3r | G5P | Guanylate kinase | 2.7.4.8 | 0.469 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.469 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.469 | |
| 4g2g | TDH | Mycocyclosin synthase | 1.14.21.9 | 0.469 | |
| 4m10 | ICD | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.469 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.468 | |
| 1rm5 | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.468 | |
| 1wwk | NAD | 307aa long hypothetical phosphoglycerate dehydrogenase | / | 0.468 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.468 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.468 | |
| 4ac0 | MIY | Tetracycline repressor protein class B from transposon Tn10 | / | 0.468 | |
| 4l8u | 9AZ | Serum albumin | / | 0.468 | |
| 1e3s | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.467 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.467 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.467 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.467 | |
| 4y1b | NAP | AntE | / | 0.467 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.466 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.466 | |
| 2o23 | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.466 | |
| 2qs3 | UBE | Glutamate receptor ionotropic, kainate 1 | / | 0.466 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.466 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.466 | |
| 3eku | CY9 | Actin-5C | / | 0.466 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.466 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.466 | |
| 1h6d | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.465 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.465 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.465 | |
| 2ylr | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.465 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.465 | |
| 3sp9 | IL2 | Peroxisome proliferator-activated receptor delta | / | 0.465 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.465 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.465 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.465 | |
| 1wa5 | GTP | GTP-binding nuclear protein Ran | / | 0.464 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.464 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.464 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.464 | |
| 4ipw | 1G7 | Mycocyclosin synthase | 1.14.21.9 | 0.464 | |
| 4l1x | NAP | Aldo-keto reductase family 1 member C2 | / | 0.464 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.463 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.463 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.463 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.463 | |
| 2xw7 | NDP | Dihydrofolate reductase | / | 0.463 | |
| 4g47 | TZF | Mycocyclosin synthase | 1.14.21.9 | 0.463 | |
| 1kqd | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.462 | |
| 1p0y | SAH | Ribulose-1,5 bisphosphate carboxylase/oxygenase large subunit N-methyltransferase, chloroplastic | 2.1.1.127 | 0.462 | |
| 1r2j | FAD | FkbI | / | 0.462 | |
| 2fvl | NAP | Aldo-keto reductase family 1 member C4 | 1.1.1.225 | 0.462 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.462 | |
| 3bgc | LJH | Gag-Pol polyprotein | 3.4.23.16 | 0.462 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.462 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.461 | |
| 1fml | RTL | Retinol dehydratase | / | 0.461 | |
| 1njf | AGS | DNA polymerase III subunit tau | 2.7.7.7 | 0.461 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.461 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.461 | |
| 2p5u | NAD | UDP-glucose 4-epimerase | / | 0.461 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.461 | |
| 2ym1 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.461 | |
| 3ndj | JHZ | Methyltransferase | / | 0.461 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.461 | |
| 3s5w | FAD | L-ornithine N(5)-monooxygenase | / | 0.461 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.461 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.461 | |
| 5jsf | NAD | 17-beta-hydroxysteroid dehydrogenase 14 | 1.1.1 | 0.461 | |
| 1dxq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.460 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 1rjd | SAM | Leucine carboxyl methyltransferase 1 | 2.1.1.233 | 0.460 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.460 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.460 | |
| 2gmv | PEP | Phosphoenolpyruvate carboxykinase, cytosolic [GTP] | 4.1.1.32 | 0.460 | |
| 2p9e | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.460 | |
| 3bhi | NAP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.460 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.460 | |
| 3tqh | NDP | Quinone oxidoreductase | / | 0.460 | |
| 4a95 | 9MT | Glycylpeptide N-tetradecanoyltransferase | / | 0.460 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.460 | |
| 1jue | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.459 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.459 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.459 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 2p41 | SAH | Genome polyprotein | / | 0.459 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.459 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.459 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.459 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.458 | |
| 1lf3 | EH5 | Plasmepsin-2 | 3.4.23.39 | 0.458 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.458 | |
| 2eeq | SAH | Diphthine synthase | / | 0.458 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 2zat | NAP | Dehydrogenase/reductase SDR family member 4 | 1.1.1.184 | 0.458 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.458 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.458 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.458 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.458 | |
| 3w0i | O11 | Vitamin D3 receptor | / | 0.458 | |
| 4die | C5P | Cytidylate kinase | / | 0.458 | |
| 4ef9 | FMN | Dihydroorotate dehydrogenase (fumarate) | / | 0.458 | |
| 4jnk | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.458 | |
| 1ay0 | TPP | Transketolase 1 | 2.2.1.1 | 0.457 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1e5q | NDP | Saccharopine dehydrogenase [NADP(+), L-glutamate-forming] | 1.5.1.10 | 0.457 | |
| 1g8j | MGD | Arsenite oxidase subunit AioA | 1.20.9.1 | 0.457 | |
| 1lsj | NAD | Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial | 1.1.1.35 | 0.457 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.457 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.457 | |
| 2xaa | NAD | Secondary alcohol dehydrogenase | / | 0.457 | |
| 2yke | YKE | Heat shock protein HSP 90-alpha | / | 0.457 | |
| 3kfr | 3TL | Gag-Pol polyprotein | / | 0.457 | |
| 3oxv | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.457 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.457 | |
| 3wv7 | ADP | Hmd co-occurring protein HcgE | / | 0.457 | |
| 4bls | APC | NTPase P4 | / | 0.457 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.457 | |
| 4dfr | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.457 | |
| 1gzu | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 1 | 2.7.7.1 | 0.456 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.456 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.456 | |
| 1y0s | 331 | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 2a2s | GSN | Glutathione S-transferase P | 2.5.1.18 | 0.456 | |
| 2o4c | NAD | Erythronate-4-phosphate dehydrogenase | / | 0.456 | |
| 2wot | ZZG | TGF-beta receptor type-1 | 2.7.11.30 | 0.456 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.456 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.456 | |
| 3ieu | GDP | GTPase Era | / | 0.456 | |
| 3kpz | ZNE | Vitamin D3 receptor | / | 0.456 | |
| 3pm9 | FAD | Putative oxidoreductase | / | 0.456 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.456 | |
| 5cmx | 0G6 | Prothrombin | 3.4.21.5 | 0.456 | |
| 5d5b | CAU | Beta-2 adrenergic receptor | / | 0.456 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.455 | |
| 2uzf | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.455 | |
| 3uku | C69 | Actin-related protein 3 | / | 0.455 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.455 | |
| 4dbs | 0HV | Aldo-keto reductase family 1 member C3 | / | 0.455 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.455 | |
| 5c3j | UQ1 | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.455 | |
| 5c3j | UQ1 | Succinate dehydrogenase cytochrome b560 | / | 0.455 | |
| 6cp4 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.455 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.454 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.454 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.454 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.454 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.454 | |
| 2wdz | NAD | Galactitol dehydrogenase | / | 0.454 | |
| 2xrl | DXT | Tetracycline repressor protein class D | / | 0.454 | |
| 3anm | SYD | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.454 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.454 | |
| 3bbr | BHY | Glutamate receptor 2 | / | 0.454 | |
| 3g5h | YTT | Mycocyclosin synthase | 1.14.21.9 | 0.454 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.454 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.454 | |
| 3q0v | LL4 | HTH-type transcriptional regulator EthR | / | 0.454 | |
| 3te5 | NAI | 5'-AMP-activated protein kinase subunit gamma | / | 0.454 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.454 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.454 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.454 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.454 | |
| 4pd6 | URI | Nucleoside permease | / | 0.454 | |
| 4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.454 | |
| 1e1k | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.453 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.453 | |
| 1kzj | CB3 | Thymidylate synthase | / | 0.453 | |
| 2xhd | 7T9 | Glutamate receptor 2 | / | 0.453 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.453 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.453 | |
| 3sm2 | 478 | Putative gag-pro-pol polyprotein | / | 0.453 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.453 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.453 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.453 | |
| 4iv6 | FDA | Isovaleryl-CoA dehydrogenase | / | 0.453 | |
| 4l4x | NDP | AmphI | / | 0.453 | |
| 1d2h | SAH | Glycine N-methyltransferase | 2.1.1.20 | 0.452 | |
| 1ebd | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.452 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.452 | |
| 1hdo | NAP | Flavin reductase (NADPH) | / | 0.452 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.452 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.452 | |
| 1pzh | NAD | Lactate dehydrogenase | / | 0.452 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.452 | |
| 1vfr | FMN | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.452 | |
| 1z7y | AA5 | Cysteine synthase 1 | 2.5.1.47 | 0.452 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.452 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.452 | |
| 3cgc | COA | Coenzyme A disulfide reductase | / | 0.452 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.452 | |
| 3duf | R1T | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.452 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.452 | |
| 3elm | 24F | Collagenase 3 | 3.4.24 | 0.452 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.452 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.452 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3o3p | GDD | Glycosyl transferase, family 2 | / | 0.452 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.452 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.452 | |
| 3zu2 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.452 | |
| 4d86 | ADP | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.452 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.452 | |
| 4el5 | D1M | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.452 | |
| 4fnc | HMU | G/T mismatch-specific thymine DNA glycosylase | 3.2.2.29 | 0.452 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.452 | |
| 4ktk | KTK | Cytochrome P450 | / | 0.452 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.452 | |
| 4qec | NAP | ElxO | / | 0.452 | |
| 4s26 | SAH | Phosphomethylpyrimidine synthase, chloroplastic | 4.1.99.17 | 0.452 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.452 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.452 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.452 | |
| 5c2t | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.452 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.452 | |
| 1n5d | NDP | Carbonyl reductase [NADPH] 1 | / | 0.451 | |
| 1o2g | 696 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1t85 | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.451 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.451 | |
| 2bsl | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.451 | |
| 2cgp | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.451 | |
| 2dsi | SAH | Diphthine synthase | / | 0.451 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.451 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.451 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.451 | |
| 3l7d | DK5 | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.451 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.451 | |
| 3o8h | O8H | HTH-type transcriptional regulator EthR | / | 0.451 | |
| 3p2o | NAD | Bifunctional protein FolD | / | 0.451 | |
| 3q71 | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.451 | |
| 3qt6 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.451 | |
| 3sfy | 3FY | Uncharacterized protein | / | 0.451 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.451 | |
| 4m11 | MXM | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.451 | |
| 5p2p | DHG | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.451 | |
| 1oo5 | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.450 | |
| 1uyi | PUZ | Heat shock protein HSP 90-alpha | / | 0.450 | |
| 1yba | NAD | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.450 | |
| 2wf1 | ZY1 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 2ylw | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.450 | |
| 3crz | FAD | Ferredoxin--NADP+ reductase | / | 0.450 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.450 | |
| 3nx4 | NAP | Putative oxidoreductase | / | 0.450 | |
| 3slz | 3TL | Putative gag-pro-pol polyprotein | / | 0.450 | |
| 3to6 | LYS_CMC | Histone acetyltransferase ESA1 | / | 0.450 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.450 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.450 | |
| 4ewo | 996 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4g3j | VNT | Lanosterol 14-alpha-demethylase | / | 0.450 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.450 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.450 | |
| 4umx | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.450 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.450 | |
| 1dyh | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.449 | |
| 1fxf | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.449 | |
| 1p4a | PCP | Pur operon repressor | / | 0.449 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.449 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.449 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.449 | |
| 2pb5 | SAH | Diphthine synthase | / | 0.449 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.449 | |
| 2qo6 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.449 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.449 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.449 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.449 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.449 | |
| 3nr4 | PYV | Abscisic acid receptor PYL2 | / | 0.449 | |
| 3vr8 | RQX | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.449 | |
| 3vr8 | RQX | Cytochrome b-large subunit | / | 0.449 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.449 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.449 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.449 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.448 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.448 | |
| 1upw | 444 | Oxysterols receptor LXR-beta | / | 0.448 | |
| 2cib | CM6 | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.448 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.448 | |
| 2gcq | DOI | Adenylosuccinate synthetase | / | 0.448 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.448 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.448 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.448 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.448 | |
| 3tne | RIT | Candidapepsin-1 | 3.4.23.24 | 0.448 | |
| 3w0c | 6DS | Vitamin D3 receptor | / | 0.448 | |
| 4b79 | NAD | Probable short-chain dehydrogenase | / | 0.448 | |
| 4bmo | FMN | Protein NrdI | / | 0.448 | |
| 4fw8 | NAI | 3-oxoacyl-(Acyl-carrier-protein) reductase | / | 0.448 | |
| 4z3d | NDP | Carbonyl reductase [NADPH] 1 | 1.1.1.184 | 0.448 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.448 | |
| 1cju | FOK | Adenylate cyclase type 2 | / | 0.447 | |
| 1cju | FOK | Adenylate cyclase type 5 | / | 0.447 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.447 | |
| 1gp2 | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.447 | |
| 1mg5 | NAI | Alcohol dehydrogenase | 1.1.1.1 | 0.447 | |
| 1u7t | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.447 | |
| 2a8y | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.447 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.447 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.447 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.447 | |
| 3pll | F06 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.447 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3u78 | E67 | Lysine-specific demethylase 7A | 1.14.11 | 0.447 | |
| 4e0i | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.447 | |
| 4f9f | GDP | Putative glycosyltransferase | / | 0.447 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.447 | |
| 4k6m | SAH | Genome polyprotein | / | 0.447 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.447 | |
| 4kgk | GTP | Uncharacterized protein | / | 0.447 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.447 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.447 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.447 | |
| 1avd | BTN | Avidin | / | 0.446 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1s20 | NAD | 2,3-diketo-L-gulonate reductase | 1.1.1.130 | 0.446 | |
| 1uye | PU9 | Heat shock protein HSP 90-alpha | / | 0.446 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.446 | |
| 2gci | MRR | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.446 | |
| 2qbu | SAH | Precorrin-2 methyltransferase | / | 0.446 | |
| 2vmy | FFO | Serine hydroxymethyltransferase | / | 0.446 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 3bpz | CMP | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 2 | / | 0.446 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.446 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3lq4 | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.446 | |
| 3o8g | O8G | HTH-type transcriptional regulator EthR | / | 0.446 | |
| 3ozd | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.446 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 3wle | NAD | (R)-specific carbonyl reductase | / | 0.446 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.446 | |
| 4c4o | NAD | SADH | / | 0.446 | |
| 4i0b | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.446 | |
| 4tkg | 09L | Tankyrase-2 | 2.4.2.30 | 0.446 | |
| 4yv1 | S4M | Spermidine synthase, putative | / | 0.446 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 5k2a | ZMA | Adenosine receptor A2a | / | 0.446 | |
| 1h2b | NAJ | NAD-dependent alcohol dehydrogenase | / | 0.445 | |
| 1i6x | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.445 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.445 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.445 | |
| 1s0z | EB1 | Vitamin D3 receptor | / | 0.445 | |
| 1u33 | LM2 | Pancreatic alpha-amylase | / | 0.445 | |
| 1uxk | NAD | Malate dehydrogenase | / | 0.445 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.445 | |
| 2f7e | 2EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2ojf | 4PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.445 | |
| 2p6k | SAH | Diphthine synthase | / | 0.445 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2v16 | C47 | Renin | 3.4.23.15 | 0.445 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.445 | |
| 3p6p | A6B | Camphor 5-monooxygenase | 1.14.15.1 | 0.445 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.445 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.445 | |
| 4e2y | JHZ | Methyltransferase | / | 0.445 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.445 | |
| 4itf | TFY | Vitamin D3 receptor | / | 0.445 | |
| 4ktl | 1CQ | Cytochrome P450 | / | 0.445 | |
| 4m9a | FDA | Acyl-CoA dehydrogenase | / | 0.445 | |
| 4mlp | 2CX | Cryptochrome-2 | / | 0.445 | |
| 4n3l | 2FN | Prothrombin | 3.4.21.5 | 0.445 | |
| 4wud | ANP | DNA gyrase subunit B | / | 0.445 | |
| 3sn6 | P0G | Beta-2 adrenergic receptor | / | 0.445 | |
| 1e2n | RCA | Thymidine kinase | / | 0.444 | |
| 1hpx | KNI | Gag-Pol polyprotein | / | 0.444 | |
| 1iy8 | NAD | Levodione reductase | / | 0.444 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.444 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.444 | |
| 1mrq | STR | Aldo-keto reductase family 1 member C1 | / | 0.444 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.444 | |
| 2dsh | SAH | Diphthine synthase | / | 0.444 | |
| 2e95 | B75 | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.444 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.444 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.444 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.444 | |
| 3em3 | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.444 | |
| 3fwj | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.444 | |
| 3glu | LYS_VAL_MET | NAD-dependent protein deacetylase sirtuin-3, mitochondrial | 3.5.1 | 0.444 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.444 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3o03 | NAP | Dehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase) | / | 0.444 | |
| 3suf | SUE | Polyprotein | / | 0.444 | |
| 3tog | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.444 | |
| 3veu | 0GO | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.444 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.444 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4ej1 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 4kqr | VPP | Peptidoglycan D,D-transpeptidase FtsI | / | 0.444 | |
| 4u7w | NDP | MxaA | / | 0.444 | |
| 4wri | OKA | Okadaic acid binding protein 2-alpha | / | 0.444 | |
| 4y4j | LNR | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 5hes | 032 | Mitogen-activated protein kinase kinase kinase 20 | 2.7.11.25 | 0.444 | |
| 1cjv | FOK | Adenylate cyclase type 2 | / | 0.443 | |
| 1cjv | FOK | Adenylate cyclase type 5 | / | 0.443 | |
| 1i5z | CMP | cAMP-activated global transcriptional regulator CRP | / | 0.443 | |
| 1jub | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.443 | |
| 1kf6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.443 | |
| 1lb9 | DNQ | Glutamate receptor 2 | / | 0.443 | |
| 1msm | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.443 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.443 | |
| 1pw6 | FRB | Interleukin-2 | / | 0.443 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.443 | |
| 1rjk | VDZ | Vitamin D3 receptor | / | 0.443 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 2b7a | IZA | Tyrosine-protein kinase JAK2 | / | 0.443 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.443 | |
| 2fxe | DR7 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 2oa7 | GTX | Glutathione S-transferase P 1 | 2.5.1.18 | 0.443 | |
| 2p2x | SAH | Diphthine synthase | / | 0.443 | |
| 2q1w | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.443 | |
| 2uzw | SS4 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.443 | |
| 2ydx | STL | Methionine adenosyltransferase 2 subunit beta | / | 0.443 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.443 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3dxm | N24 | Actin-related protein 3 | / | 0.443 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.443 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.443 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3il1 | B5D | Glutamate receptor 2 | / | 0.443 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.443 | |
| 3ojx | NAP | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.443 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.443 | |
| 3r2f | PB0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 3tvu | B37 | Acetyl-CoA carboxylase | / | 0.443 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.443 | |
| 3vf6 | 0H6 | Glucokinase | 2.7.1.2 | 0.443 | |
| 4c02 | TAK | Activin receptor type-1 | 2.7.11.30 | 0.443 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.443 | |
| 4u9y | COA | Alpha-tubulin N-acetyltransferase 1 | / | 0.443 | |
| 5koi | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.443 | |
| 13gs | SAS | Glutathione S-transferase P | 2.5.1.18 | 0.442 | |
| 1dor | FMN | Dihydroorotate dehydrogenase A (fumarate) | 1.3.98.1 | 0.442 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1g1a | NAD | dTDP-glucose 4,6-dehydratase | / | 0.442 | |
| 1lny | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.442 | |
| 1mrw | K57 | Gag-Pol polyprotein | 3.4.23.16 | 0.442 | |
| 1qlt | FAD | Vanillyl-alcohol oxidase | 1.1.3.38 | 0.442 | |
| 1s7g | NAD | NAD-dependent protein deacylase 2 | / | 0.442 | |
| 2fn7 | NAD | Lactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase | / | 0.442 | |
| 2iej | S48 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.442 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.442 | |
| 2wns | OMP | Uridine 5'-monophosphate synthase | 2.4.2.10 | 0.442 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.442 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.442 | |
| 3czr | 3CZ | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.442 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.442 | |
| 3fwg | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.442 | |
| 3phc | IM5 | Purine nucleoside phosphorylase | / | 0.442 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.442 | |
| 3vrv | YSD | Vitamin D3 receptor | / | 0.442 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.442 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.442 | |
| 4bqu | CLR | Japanin | / | 0.442 | |
| 4ead | 0NP | Thymidine phosphorylase | 2.4.2.4 | 0.442 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.442 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.442 | |
| 4lz8 | 1YX | Glutamate receptor 2 | / | 0.442 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.442 | |
| 4wso | NAD | Probable nicotinate-nucleotide adenylyltransferase | / | 0.442 | |
| 5fdg | 0N8 | Polymerase acidic protein | / | 0.442 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.442 | |
| 3eml | ZMA | Adenosine receptor A2a | / | 0.442 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.441 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.441 | |
| 1ng4 | FAD | Glycine oxidase | 1.4.3.19 | 0.441 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1pr9 | NAP | L-xylulose reductase | 1.1.1.10 | 0.441 | |
| 1tl7 | ONM | Adenylate cyclase type 2 | / | 0.441 | |
| 1tl7 | ONM | Adenylate cyclase type 5 | / | 0.441 | |
| 1tu3 | GNP | Ras-related protein Rab-5A | / | 0.441 | |
| 1xtr | GNP | GTP-binding protein Rheb | / | 0.441 | |
| 2b0m | 201 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.441 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.441 | |
| 2p3b | 3TL | V-1 PROTEASE protein | / | 0.441 | |
| 2p3b | 3TL | V-1 protease | / | 0.441 | |
| 2uzh | CDP | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.441 | |
| 2uzu | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.441 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.441 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.441 | |
| 2zb3 | NDP | Prostaglandin reductase 2 | 1.3.1.48 | 0.441 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.441 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3m6i | NAD | L-arabinitol 4-dehydrogenase | 1.1.1.12 | 0.441 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.441 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.441 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.441 | |
| 4dx7 | DM2 | Multidrug efflux pump subunit AcrB | / | 0.441 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.441 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4uyf | 73B | Bromodomain-containing protein 2 | / | 0.441 | |
| 4wo5 | 324 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.441 | |
| 5ccy | TMP | Polymerase acidic protein | / | 0.441 | |
| 1ahi | CHO | 7-alpha-hydroxysteroid dehydrogenase | 1.1.1.159 | 0.440 | |
| 1diu | BDM | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1dxy | NAD | D-2-hydroxyisocaproate dehydrogenase | 1.1.1 | 0.440 | |
| 1gj5 | 130 | Prothrombin | 3.4.21.5 | 0.440 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.440 | |
| 1jk3 | BAT | Macrophage metalloelastase | 3.4.24.65 | 0.440 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.440 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.440 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.440 | |
| 1n2s | NAI | dTDP-4-dehydrorhamnose reductase | 1.1.1.133 | 0.440 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 1uyu | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.440 | |
| 1xzq | FON | tRNA modification GTPase MnmE | 3.6.5 | 0.440 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 2bgl | NAJ | Secoisolariciresinol dehydrogenase | 1.1.1.331 | 0.440 | |
| 2hiz | LIJ | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2iwh | ANP | Elongation factor 3A | / | 0.440 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.440 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.440 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.440 | |
| 3abi | NAD | Uncharacterized protein | / | 0.440 | |
| 3ae4 | N1M | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | 1.3.5.1 | 0.440 | |
| 3ae4 | N1M | Succinate dehydrogenase cytochrome b560 subunit, mitochondrial | / | 0.440 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.440 | |
| 3bv2 | P38 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3ijr | NAD | Oxidoreductase, short chain dehydrogenase/reductase family | / | 0.440 | |
| 3ik6 | HCZ | Glutamate receptor 2 | / | 0.440 | |
| 3nmh | PYV | Abscisic acid receptor PYL2 | / | 0.440 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3vfq | AR6 | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.440 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.440 | |
| 4e0h | FAD | Mitochondrial FAD-linked sulfhydryl oxidase ERV1 | 1.8.3.2 | 0.440 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 4iql | FMN | Enoyl-(Acyl-carrier-protein) reductase II | / | 0.440 | |
| 5a88 | ADP | Riboflavin biosynthesis protein RibF | 2.7.1.26 | 0.440 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.440 |