sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4eqe | KAA | Histidine triad nucleotide-binding protein 1 | 3 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 4eqe | KAA | Histidine triad nucleotide-binding protein 1 | 3 | 1.000 | |
| 4eqg | A5A | Histidine triad nucleotide-binding protein 1 | 3 | 0.739 | |
| 5i2f | BS5 | Histidine triad nucleotide-binding protein 1 | 3 | 0.616 | |
| 3qgz | ADN | Histidine triad nucleotide-binding protein 1 | 3 | 0.587 | |
| 3oxk | 5GP | Histidine triad nucleotide-binding protein | 3 | 0.578 | |
| 1rzy | 5AS | Histidine triad nucleotide-binding protein 1 | 3 | 0.573 | |
| 1av5 | AP2 | Histidine triad nucleotide-binding protein 1 | 3 | 0.523 | |
| 2pg0 | FAD | Acyl-CoA dehydrogenase | / | 0.502 | |
| 5il2 | SAH | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.496 | |
| 2pa7 | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.492 | |
| 2iqg | F2I | Beta-secretase 1 | 3.4.23.46 | 0.491 | |
| 3cib | 314 | Beta-secretase 1 | 3.4.23.46 | 0.491 | |
| 2ntr | L00 | Beta-secretase 1 | 3.4.23.46 | 0.489 | |
| 4anx | 534 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.488 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.485 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.485 | |
| 3vt7 | VDX | Vitamin D3 receptor | / | 0.483 | |
| 2cts | COA | Citrate synthase, mitochondrial | 2.3.3.1 | 0.481 | |
| 4z64 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.481 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.480 | |
| 2q2q | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.479 | |
| 3dm6 | 757 | Beta-secretase 1 | 3.4.23.46 | 0.479 | |
| 1d4a | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.478 | |
| 4b8z | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.478 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.477 | |
| 4dpl | NAP | Malonyl-CoA reductase | 1.2.1.75 | 0.477 | |
| 4lxa | 1YS | Beta-secretase 1 | 3.4.23.46 | 0.477 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.477 | |
| 2f3f | AXF | Beta-secretase 1 | 3.4.23.46 | 0.476 | |
| 3n1s | 5GP | Purine nucleoside phosphoramidase | / | 0.476 | |
| 2b8t | THM | Thymidine kinase | / | 0.475 | |
| 2dte | NAI | Glucose 1-dehydrogenase related protein | / | 0.475 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.475 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.475 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.475 | |
| 3ndj | JHZ | Methyltransferase | / | 0.475 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.475 | |
| 4ryv | ZEA | Protein LlR18A | / | 0.475 | |
| 4x81 | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.475 | |
| 1qbg | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.474 | |
| 4fdn | FAD | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.474 | |
| 4knz | CB3 | Thymidylate synthase | / | 0.474 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.474 | |
| 3dv5 | BAV | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.473 | |
| 4b6u | M7G | Eukaryotic translation initiation factor 4E type 3 | / | 0.473 | |
| 2cgv | 3B3 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.472 | |
| 2e1z | B4P | Propionate kinase | / | 0.472 | |
| 3g1r | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.472 | |
| 4l4x | NDP | AmphI | / | 0.472 | |
| 1uym | PU3 | Heat shock protein HSP 90-beta | / | 0.471 | |
| 1xel | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.471 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.471 | |
| 2yee | 2EC | Heat shock protein HSP 90-alpha | / | 0.471 | |
| 3fkt | SII | Beta-secretase 1 | 3.4.23.46 | 0.471 | |
| 3vtb | TKA | Vitamin D3 receptor | / | 0.471 | |
| 4bb6 | HD1 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.471 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.471 | |
| 1nmd | ATP | Major actin | / | 0.470 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.470 | |
| 2e9u | A25 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.470 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.470 | |
| 3c3e | GDP | 2-phospho-L-lactate transferase | / | 0.470 | |
| 3gb4 | D3M | DdmC | / | 0.470 | |
| 3ixj | 586 | Beta-secretase 1 | 3.4.23.46 | 0.470 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.470 | |
| 4req | 5AD | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.470 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.469 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.469 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.469 | |
| 4bcs | BTN | Avidin-related protein 4/5 | / | 0.469 | |
| 4ewn | 0VR | Imidazole glycerol phosphate synthase subunit HisF | 4.1.3 | 0.469 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.469 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.469 | |
| 4ra3 | TFX | Beta-2-microglobulin | / | 0.469 | |
| 5cvc | PLP | Serine racemase | / | 0.469 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.468 | |
| 2uzt | SS3 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.468 | |
| 3cge | COA | Coenzyme A disulfide reductase | / | 0.468 | |
| 3l5l | FMN | Xenobiotic reductase | / | 0.468 | |
| 4a6b | QG8 | Gag-Pol polyprotein | 3.4.23.16 | 0.468 | |
| 4iae | 1DX | Alr2278 protein | / | 0.468 | |
| 1icq | OPD | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.467 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.467 | |
| 3bgb | LJG | Gag-Pol polyprotein | 3.4.23.16 | 0.467 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.467 | |
| 4kz0 | 1UJ | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.467 | |
| 4ydu | ADP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.467 | |
| 1uyd | PU8 | Heat shock protein HSP 90-alpha | / | 0.466 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.466 | |
| 2x6o | 2TC | Tetracycline repressor protein class D | / | 0.466 | |
| 3juo | AJD | Phenazine biosynthesis protein A/B | / | 0.466 | |
| 3ms5 | REE | Gamma-butyrobetaine dioxygenase | 1.14.11.1 | 0.466 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.466 | |
| 1bo4 | COA | Aminoglycoside-(3)-N-acetyltransferase | / | 0.465 | |
| 1jtq | LY3 | Thymidylate synthase | / | 0.465 | |
| 1kbo | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.465 | |
| 1kvs | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.465 | |
| 3fx5 | KNI | Gag-Pol polyprotein | 3.4.23.16 | 0.465 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.465 | |
| 3vt4 | 5YI | Vitamin D3 receptor | / | 0.465 | |
| 3zhb | NAP | Putative dehydrogenase | / | 0.465 | |
| 4bfy | ZVY | Pantothenate kinase | 2.7.1.33 | 0.465 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.465 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.464 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.464 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.464 | |
| 2xy9 | 3ES | Angiotensin-converting enzyme | 3.2.1 | 0.464 | |
| 3aiv | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic | 3.2.1.182 | 0.464 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.464 | |
| 3cb2 | GDP | Tubulin gamma-1 chain | / | 0.464 | |
| 4rrv | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.464 | |
| 4v2g | CTC | Tetracycline repressor protein class D | / | 0.464 | |
| 1atn | ATP | Actin, alpha skeletal muscle | / | 0.463 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.463 | |
| 1uyh | PU0 | Heat shock protein HSP 90-alpha | / | 0.463 | |
| 2e9n | 76A | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.463 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.463 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.463 | |
| 4az0 | S61 | Lysosomal protective protein | 3.4.16.5 | 0.463 | |
| 1hon | GNH | Adenylosuccinate synthetase | / | 0.462 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.462 | |
| 2hfu | MEV | Mevalonate kinase | / | 0.462 | |
| 3c3d | FO1 | 2-phospho-L-lactate transferase | / | 0.462 | |
| 3dop | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.462 | |
| 3ft8 | MOJ | Heat shock protein HSP 90-alpha | / | 0.462 | |
| 3k5c | 0BI | Beta-secretase 1 | 3.4.23.46 | 0.462 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.462 | |
| 5a4k | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.462 | |
| 1hvy | D16 | Thymidylate synthase | 2.1.1.45 | 0.461 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.461 | |
| 1nlm | UD1 | UDP-N-acetylglucosamine--N-acetylmuramyl-(pentapeptide) pyrophosphoryl-undecaprenol N-acetylglucosamine transferase | / | 0.461 | |
| 2ph8 | 35A | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 2ylx | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.461 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.461 | |
| 3uko | NAD | Alcohol dehydrogenase class-3 | / | 0.461 | |
| 3up0 | D7S | aceDAF-12 | / | 0.461 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.461 | |
| 1a59 | COA | 2-methylcitrate synthase | / | 0.460 | |
| 3k5g | BJC | Beta-secretase 1 | 3.4.23.46 | 0.460 | |
| 3n6u | TSU | HTH-type transcriptional regulator TsaR | / | 0.460 | |
| 3slk | NDP | Polyketide synthase extender module 2 | / | 0.460 | |
| 4e2z | JHZ | Methyltransferase | / | 0.460 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.460 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.460 | |
| 1h5q | NAP | NADP-dependent mannitol dehydrogenase | 1.1.1.138 | 0.459 | |
| 1jwt | BLI | Prothrombin | 3.4.21.5 | 0.459 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.459 | |
| 1v5z | 2HC | Major NAD(P)H-flavin oxidoreductase | 1.6.99 | 0.459 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.459 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 2vu3 | LZE | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.459 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.459 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.459 | |
| 4c8e | C5P | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | / | 0.459 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.459 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.459 | |
| 4k8s | 1QT | Beta-secretase 1 | 3.4.23.46 | 0.459 | |
| 4n3r | 2GU | Tankyrase-1 | 2.4.2.30 | 0.459 | |
| 1e6w | NAD | 3-hydroxyacyl-CoA dehydrogenase type-2 | 1.1.1.35 | 0.458 | |
| 1f4g | TP4 | Thymidylate synthase | / | 0.458 | |
| 1xs7 | MMI | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3o26 | NDP | Salutaridine reductase | / | 0.458 | |
| 3own | 3OW | Renin | 3.4.23.15 | 0.458 | |
| 3qqs | 17C | Anthranilate phosphoribosyltransferase | / | 0.458 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.458 | |
| 3zhz | FM7 | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.458 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.458 | |
| 4n6b | COA | Uncharacterized protein | / | 0.458 | |
| 5b0o | ADP | Flagellum-specific ATP synthase | 3.6.3.14 | 0.458 | |
| 1bv9 | XV6 | Gag-Pol polyprotein | 3.4.23.16 | 0.457 | |
| 1c70 | L75 | Protease | / | 0.457 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.457 | |
| 1ork | ATC | Tetracycline repressor protein class D | / | 0.457 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.457 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.457 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.457 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.457 | |
| 3um6 | 1CY | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.457 | |
| 3vt6 | 5YI | Vitamin D3 receptor | / | 0.457 | |
| 3zh8 | C58 | Protein kinase C iota type | 2.7.11.13 | 0.457 | |
| 4axa | RKD | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.457 | |
| 4b8w | NAP | GDP-L-fucose synthase | 1.1.1.271 | 0.457 | |
| 4bek | XK0 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4e32 | DWN | Methyltransferase | / | 0.457 | |
| 4eil | UMP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.457 | |
| 4fs4 | H24 | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.456 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.456 | |
| 2ejz | SAH | Diphthine synthase | / | 0.456 | |
| 2hq9 | FAD | Mll6688 protein | / | 0.456 | |
| 2q5g | 1FA | Peroxisome proliferator-activated receptor delta | / | 0.456 | |
| 2uuk | 897 | Prothrombin | 3.4.21.5 | 0.456 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.456 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.456 | |
| 3n19 | FNR | Xenobiotic reductase | / | 0.456 | |
| 3o6o | 94M | Heat shock protein 83 | / | 0.456 | |
| 3ppk | FNI | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.456 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 4a6c | QG9 | Gag-Pol polyprotein | 3.4.23.16 | 0.456 | |
| 4da8 | BG2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.456 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.456 | |
| 1a7x | FKA | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.455 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.455 | |
| 1txz | APR | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.455 | |
| 1uad | GNP | Ras-related protein Ral-A | / | 0.455 | |
| 1uu9 | BI3 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.455 | |
| 1zdw | FLV | Prenyltransferase | / | 0.455 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.455 | |
| 2vij | C44 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 2yy7 | NAD | L-threonine dehydrogenase | / | 0.455 | |
| 3stw | 2TD | Methylketone synthase I | / | 0.455 | |
| 3vf3 | 0GS | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 3zmg | 6Z0 | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.455 | |
| 4iah | 1DX | Alr2278 protein | / | 0.455 | |
| 4rr7 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.455 | |
| 4ysj | ADP | Calmodulin-like domain protein kinase | / | 0.455 | |
| 1h61 | PDN | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1ty8 | ADP | Probable ADP-ribose 1''-phosphate phosphatase YML087W | 3.1.3.84 | 0.454 | |
| 1uyf | PU1 | Heat shock protein HSP 90-alpha | / | 0.454 | |
| 2iea | TDP | Pyruvate dehydrogenase E1 component | 1.2.4.1 | 0.454 | |
| 2ph6 | 712 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 2wf4 | ZY4 | Beta-secretase 1 | 3.4.23.46 | 0.454 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.454 | |
| 3iah | NAP | Putative oxoacyl-(Acyl carrier protein) reductase | / | 0.454 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.454 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.453 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 1muu | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.453 | |
| 1mv8 | GDX | GDP-mannose 6-dehydrogenase | 1.1.1.132 | 0.453 | |
| 1udc | UFM | UDP-glucose 4-epimerase | 5.1.3.2 | 0.453 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.453 | |
| 2db3 | ANP | ATP-dependent RNA helicase vasa, isoform A | 3.6.4.13 | 0.453 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.453 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.453 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3ei8 | PL5 | LL-diaminopimelate aminotransferase, chloroplastic | / | 0.453 | |
| 3ggg | NAD | Prephenate dehydrogenase | / | 0.453 | |
| 3gy0 | NAP | NAD(P)-dependent oxidoreductase | / | 0.453 | |
| 3lpj | Z75 | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.453 | |
| 3q9b | B3N | Acetylpolyamine amidohydrolase | / | 0.453 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.453 | |
| 4anv | 751 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.453 | |
| 4fm8 | 0UQ | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4k9h | 1QU | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 4lc7 | 1WP | Beta-secretase 1 | 3.4.23.46 | 0.453 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.453 | |
| 1c6y | MK1 | Protease | / | 0.452 | |
| 1dna | CB3 | Thymidylate synthase | / | 0.452 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1kw0 | H4B | Phenylalanine-4-hydroxylase | 1.14.16.1 | 0.452 | |
| 1kzk | JE2 | Gag-Pol polyprotein | 3.4.23.16 | 0.452 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.452 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.452 | |
| 2e20 | B4P | Propionate kinase | / | 0.452 | |
| 2onm | ADP | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.452 | |
| 2vnn | CM7 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 2vyn | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.452 | |
| 2zl9 | VDA | Vitamin D3 receptor | / | 0.452 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.452 | |
| 3ecg | 065 | Gag-Pol polyprotein | 3.4.23.47 | 0.452 | |
| 3skg | PB8 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.452 | |
| 4cjw | CBJ | Integrase | / | 0.452 | |
| 4imo | PWZ | Prostaglandin-H2 D-isomerase | 5.3.99.2 | 0.452 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.452 | |
| 1nzq | 162 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1qor | NDP | Quinone oxidoreductase 1 | / | 0.451 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.451 | |
| 2i3g | NAP | N-acetyl-gamma-glutamyl-phosphate reductase | 1.2.1.38 | 0.451 | |
| 2ohv | NHL | Glutamate racemase | / | 0.451 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 2v7q | ATP | ATP synthase subunit alpha, mitochondrial | / | 0.451 | |
| 2v7q | ATP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.451 | |
| 2ym2 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.451 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.451 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.451 | |
| 3aiq | HBO | 4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase 1b, chloroplastic | 3.2.1.182 | 0.451 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.451 | |
| 3hrc | ATP | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.451 | |
| 3ids | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.451 | |
| 3qw4 | U5P | Orotidine-5-phosphate decarboxylase/orotate phosphoribosyltransferase, putative | / | 0.451 | |
| 3vt9 | YI4 | Vitamin D3 receptor | / | 0.451 | |
| 4eua | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.451 | |
| 4exg | 916 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.451 | |
| 4k42 | ADP | Actin, alpha skeletal muscle | / | 0.451 | |
| 4nh8 | 2LC | Heat shock protein HSP 90-alpha | / | 0.451 | |
| 5a2y | UTP | Mitochondrial poly(A) polymerase | / | 0.451 | |
| 1daa | PLP | D-alanine aminotransferase | 2.6.1.21 | 0.450 | |
| 1pyd | TDP | Pyruvate decarboxylase isozyme 1 | / | 0.450 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1rkg | VD1 | Vitamin D3 receptor | / | 0.450 | |
| 1t0i | FMN | NAD(P)H-dependent FMN reductase LOT6 | / | 0.450 | |
| 1t4v | 14A | Prothrombin | 3.4.21.5 | 0.450 | |
| 1x28 | PGU | Aspartate aminotransferase | 2.6.1.1 | 0.450 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.450 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.450 | |
| 2hb8 | MVD | Vitamin D3 receptor | / | 0.450 | |
| 2p9g | NAI | D-3-phosphoglycerate dehydrogenase | 1.1.1.95 | 0.450 | |
| 2wf0 | ZY0 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3dv1 | AR9 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.450 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.450 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.450 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.450 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 3rvh | HQ2 | Lysine-specific demethylase 4A | 1.14.11 | 0.450 | |
| 3uwl | FOZ | Thymidylate synthase | / | 0.450 | |
| 4egu | 5GP | Putative histidine triad (HIT) protein | / | 0.450 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.450 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.450 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.450 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.450 | |
| 5dp2 | NAP | CurF | / | 0.450 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.449 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.449 | |
| 1kbq | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.449 | |
| 1kfc | IPL | Tryptophan synthase alpha chain | / | 0.449 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.449 | |
| 1ndi | COA | Carnitine O-acetyltransferase | 2.3.1.7 | 0.449 | |
| 1xdu | SFG | Aclacinomycin 10-hydroxylase RdmB | 4.1.1 | 0.449 | |
| 2e0n | SAH | Precorrin-2 C20-methyltransferase | / | 0.449 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.449 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.449 | |
| 2zlc | VDX | Vitamin D3 receptor | / | 0.449 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.449 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.449 | |
| 3haz | FAD | Bifunctional protein PutA | / | 0.449 | |
| 3hbf | MYC | Flavonoid 3-O-glucosyltransferase | 2.4.1 | 0.449 | |
| 3my5 | RFZ | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 3tx1 | FAD | UDP-N-acetylenolpyruvoylglucosamine reductase | / | 0.449 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.449 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.449 | |
| 3w0t | HPU | Lactoylglutathione lyase | 4.4.1.5 | 0.449 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.449 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.449 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.449 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.449 | |
| 4xwt | U5P | Ribonuclease J | / | 0.449 | |
| 1bwl | FMN | NADPH dehydrogenase 1 | 1.6.99.1 | 0.448 | |
| 1gpu | THD | Transketolase 1 | 2.2.1.1 | 0.448 | |
| 1h36 | R88 | Squalene--hopene cyclase | 4.2.1.129 | 0.448 | |
| 1llu | NAD | Alcohol dehydrogenase | / | 0.448 | |
| 1mqe | APR | MutT/nudix family protein | / | 0.448 | |
| 1ndy | FR3 | Adenosine deaminase | 3.5.4.4 | 0.448 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.448 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.448 | |
| 2azn | NAP | 2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase | / | 0.448 | |
| 2azz | TCH | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.448 | |
| 2c3l | IDZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.448 | |
| 2hb7 | O1C | Vitamin D3 receptor | / | 0.448 | |
| 2jah | NDP | Clavaldehyde dehydrogenase | / | 0.448 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.448 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.448 | |
| 3djl | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.448 | |
| 3rn8 | RN8 | Glutamate receptor 2 | / | 0.448 | |
| 3um5 | CP6 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.448 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.448 | |
| 4fhi | 0S4 | Vitamin D3 receptor A | / | 0.448 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.448 | |
| 4pkh | ADP | Actin, alpha skeletal muscle | / | 0.448 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.448 | |
| 1b8v | NAD | Malate dehydrogenase | / | 0.447 | |
| 1bux | PPS | Nucleoside diphosphate kinase, cytosolic | 2.7.4.6 | 0.447 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.447 | |
| 1l2t | ATP | Uncharacterized ABC transporter ATP-binding protein MJ0796 | / | 0.447 | |
| 2bro | DF2 | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.447 | |
| 2c27 | MA8 | Mycothiol acetyltransferase | 2.3.1.189 | 0.447 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.447 | |
| 2wez | ZYE | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 2wug | HPK | 4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase | 3.7.1.17 | 0.447 | |
| 3bk2 | U5P | Ribonuclease J | / | 0.447 | |
| 3fnl | SHA | Lactoperoxidase | / | 0.447 | |
| 3hxf | BD9 | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.447 | |
| 3prf | FP3 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.447 | |
| 3vt3 | VDX | Vitamin D3 receptor | / | 0.447 | |
| 4aic | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.447 | |
| 4fco | 0U4 | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4fog | C2F | Thymidylate synthase ThyA | / | 0.447 | |
| 4rfl | NDP | Glycerol-1-phosphate dehydrogenase [NAD(P)+] | / | 0.447 | |
| 4xnw | 2ID | P2Y purinoceptor 1 | / | 0.447 | |
| 1j49 | NAD | D-lactate dehydrogenase | 1.1.1.28 | 0.446 | |
| 1lik | ADN | Adenosine kinase | 2.7.1.20 | 0.446 | |
| 1lwi | NAP | 3-alpha-hydroxysteroid dehydrogenase | 1.1.1.50 | 0.446 | |
| 1nzd | UPG | DNA beta-glucosyltransferase | / | 0.446 | |
| 1rk3 | VDX | Vitamin D3 receptor | / | 0.446 | |
| 2ad5 | ADP | CTP synthase | / | 0.446 | |
| 2ed3 | SAH | Diphthine synthase | / | 0.446 | |
| 2g94 | ZPQ | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.446 | |
| 2q28 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.446 | |
| 2vcm | M11 | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 2xiq | 5AD | Methylmalonyl-CoA mutase, mitochondrial | / | 0.446 | |
| 3ggu | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.446 | |
| 3h7u | NAP | NADPH-dependent aldo-keto reductase, chloroplastic | / | 0.446 | |
| 3l9h | EMQ | Kinesin-like protein KIF11 | / | 0.446 | |
| 3stv | 3HO | Methylketone synthase I | / | 0.446 | |
| 3tox | NAP | Putative oxidoreductase | / | 0.446 | |
| 3vrt | YS2 | Vitamin D3 receptor | / | 0.446 | |
| 3w0j | T08 | Vitamin D3 receptor | / | 0.446 | |
| 3w8q | AGS | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.446 | |
| 4d2d | ALA_ALA_ALA | Di-or tripeptide:H+ symporter | / | 0.446 | |
| 4die | C5P | Cytidylate kinase | / | 0.446 | |
| 4dz5 | NAP | Aldo-keto reductase family 1 member C3 | / | 0.446 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.446 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4kl1 | PCG | Potassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4 | / | 0.446 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.446 | |
| 4pmj | NAP | Putative oxidoreductase | / | 0.446 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.446 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.446 | |
| 4yag | NAI | C alpha-dehydrogenase | / | 0.446 | |
| 4z61 | ILE_THR_GLN_TYS_TYS | Phytosulfokine receptor 1 | 2.7.11.1 | 0.446 | |
| 5cdg | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 5kje | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.446 | |
| 1d0l | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.445 | |
| 1fm6 | BRL | Peroxisome proliferator-activated receptor gamma | / | 0.445 | |
| 1gg5 | FAD | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.445 | |
| 1guf | NDP | Enoyl-[acyl-carrier-protein] reductase 1, mitochondrial | 1.3.1.10 | 0.445 | |
| 1klm | SPP | Gag-Pol polyprotein | 2.7.7.49 | 0.445 | |
| 1rwb | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.445 | |
| 2bif | ANP | 6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 4 | 2.7.1.105 | 0.445 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.445 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.445 | |
| 2tct | CTC | Tetracycline repressor protein class D | / | 0.445 | |
| 2vkm | BSD | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 2x7h | PFN | Prostaglandin reductase 3 | 1 | 0.445 | |
| 3anm | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | 1.1.1.267 | 0.445 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.445 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.445 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.445 | |
| 3s2v | 3HU | Glutamate receptor ionotropic, kainate 1 | / | 0.445 | |
| 3tm0 | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.445 | |
| 3ty3 | GGG | Homoisocitrate dehydrogenase | 1.1.1.87 | 0.445 | |
| 3zhq | TPP | Multifunctional 2-oxoglutarate metabolism enzyme | 1.2.4.2 | 0.445 | |
| 3zpu | M8B | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.445 | |
| 4ez8 | DHF | Thymidylate synthase | 2.1.1.45 | 0.445 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.445 | |
| 4kx6 | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.445 | |
| 4phl | PIL | Phosphodiesterase | / | 0.445 | |
| 1bsv | NDP | GDP-L-fucose synthase | / | 0.444 | |
| 1cyd | NDP | Carbonyl reductase [NADPH] 2 | 1.1.1.184 | 0.444 | |
| 1mk1 | APR | MutT/nudix family protein | / | 0.444 | |
| 1r8b | ATP | CCA-adding enzyme | 2.7.7.72 | 0.444 | |
| 1tkg | SSA | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 1wam | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.444 | |
| 2brm | DFZ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.444 | |
| 2fr8 | NAP | NAD(P) transhydrogenase subunit beta | 1.6.1.2 | 0.444 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2w4j | ADP | Death-associated protein kinase 1 | 2.7.11.1 | 0.444 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 2zev | IPE | Geranylgeranyl pyrophosphate synthase | / | 0.444 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.444 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.444 | |
| 3duy | AFJ | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 3hf6 | LX0 | Tryptophan 5-hydroxylase 1 | 1.14.16.4 | 0.444 | |
| 3jpu | TY4 | Transcriptional activator protein LasR | / | 0.444 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 3tfy | MET_LEU_GLY_PRO | N-alpha-acetyltransferase 50 | 2.3.1 | 0.444 | |
| 3wtk | TH4 | Acetylcholine-binding protein | / | 0.444 | |
| 4at0 | FAD | Possible succinate dehydrogenase | / | 0.444 | |
| 4b3a | TAC | Tetracycline repressor protein class D | / | 0.444 | |
| 4d03 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.444 | |
| 4dri | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.444 | |
| 4dri | RAP | Peptidyl-prolyl cis-trans isomerase FKBP5 | 5.2.1.8 | 0.444 | |
| 4euf | NAD | Trans-2-enoyl-CoA reductase [NADH] | / | 0.444 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.444 | |
| 4i0h | 1BL | Beta-secretase 1 | 3.4.23.46 | 0.444 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.444 | |
| 4ri1 | ACO | UDP-4-amino-4,6-dideoxy-N-acetyl-beta-L-altrosamine N-acetyltransferase | 2.3.1.202 | 0.444 | |
| 5ap7 | SVE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.444 | |
| 1a4w | QWE | Prothrombin | 3.4.21.5 | 0.443 | |
| 1g9r | UPF | LgtC | / | 0.443 | |
| 1lf2 | R37 | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 1mtc | GPR | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.443 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.443 | |
| 1nw4 | IMH | Purine nucleoside phosphorylase | / | 0.443 | |
| 1ojt | FAD | Dihydrolipoyl dehydrogenase | / | 0.443 | |
| 1q19 | SSC | Carbapenam-3-carboxylate synthase | 6.3.3.6 | 0.443 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.443 | |
| 1rej | B1L | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.443 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.443 | |
| 1tys | DHF | Thymidylate synthase | / | 0.443 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.443 | |
| 1zq5 | E04 | Aldo-keto reductase family 1 member C3 | / | 0.443 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.443 | |
| 2gjn | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.443 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.443 | |
| 2i4u | DJR | Protease | / | 0.443 | |
| 2qu6 | 857 | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.443 | |
| 3a1n | NAD | NDP-sugar epimerase | / | 0.443 | |
| 3dr1 | C5D | Vitamin D3 receptor A | / | 0.443 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.443 | |
| 3i7e | DJR | Gag-Pol polyprotein | / | 0.443 | |
| 3jv7 | NAD | Secondary alcohol dehydrogenase | / | 0.443 | |
| 3mzt | TFX | Beta-2-microglobulin | / | 0.443 | |
| 3oqk | S52 | Renin | 3.4.23.15 | 0.443 | |
| 3ovs | CTP | CCA-adding enzyme | 2.7.7.72 | 0.443 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.443 | |
| 3rwp | ABQ | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.443 | |
| 3v0p | 4GW | Histo-blood group ABO system transferase | / | 0.443 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.443 | |
| 4fse | 0VA | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4g1y | 0VO | Vitamin D3 receptor A | / | 0.443 | |
| 4g36 | SLU | Luciferin 4-monooxygenase | 1.13.12.7 | 0.443 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.443 | |
| 4i5c | C5I | Tyrosine-protein kinase JAK1 | / | 0.443 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.443 | |
| 5fkk | TDC | Tetracycline repressor protein class D | / | 0.443 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.443 | |
| 1d0m | BLG | Membrane-bound lytic murein transglycosylase B | 4.2.2.n1 | 0.442 | |
| 1d9i | 00P | Prothrombin | 3.4.21.5 | 0.442 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.442 | |
| 1fwm | CB3 | Thymidylate synthase | / | 0.442 | |
| 1gae | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.442 | |
| 1hrv | SDZ | Genome polyprotein | / | 0.442 | |
| 1pax | DHQ | Poly [ADP-ribose] polymerase 1 | 2.4.2.30 | 0.442 | |
| 1xse | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 1ybm | NAP | Uncharacterized protein At5g02240 | / | 0.442 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.442 | |
| 2bkk | ADP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.442 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.442 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2gfs | PQB | Mitogen-activated protein kinase 14 | / | 0.442 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.442 | |
| 2oh0 | 2PY | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2ozr | GG1 | Collagenase 3 | 3.4.24 | 0.442 | |
| 2rbe | NDP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.442 | |
| 2vke | TAC | Tetracycline repressor protein class D | / | 0.442 | |
| 2vn0 | TDZ | Cytochrome P450 2C8 | / | 0.442 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.442 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.442 | |
| 3jyo | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.442 | |
| 3mt8 | 17T | Glycogen phosphorylase, muscle form | 2.4.1.1 | 0.442 | |
| 3oog | YTP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 3seq | NXX | Glutamine-dependent NAD(+) synthetase | 6.3.5.1 | 0.442 | |
| 4ax9 | N5N | Prothrombin | 3.4.21.5 | 0.442 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.442 | |
| 4dh6 | 0KN | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4e2x | TYD | Methyltransferase | / | 0.442 | |
| 4eu4 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.442 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.442 | |
| 4lxk | 1YT | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.442 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.442 | |
| 5c4f | UPG | Histo-blood group ABO system transferase | / | 0.442 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.442 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.442 | |
| 6gsu | GPS | Glutathione S-transferase Mu 1 | 2.5.1.18 | 0.442 | |
| 1a8p | FAD | Ferredoxin--NADP reductase | / | 0.441 | |
| 1ae1 | NAP | Tropinone reductase 1 | / | 0.441 | |
| 1c0f | ATP | Major actin | / | 0.441 | |
| 1d4h | BEH | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1gco | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.441 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.441 | |
| 1vso | AT1 | Glutamate receptor ionotropic, kainate 1 | / | 0.441 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.441 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 2brb | PFQ | Serine/threonine-protein kinase Chk1 | 2.7.11.1 | 0.441 | |
| 2ejv | NAD | L-threonine 3-dehydrogenase | / | 0.441 | |
| 2fwz | H71 | Heat shock protein HSP 90-alpha | / | 0.441 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.441 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.441 | |
| 2wn6 | NDP | ADP-ribosyltransferase enzymatic component | / | 0.441 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.441 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 3dmt | NAD | Glyceraldehyde-3-phosphate dehydrogenase, glycosomal | 1.2.1.12 | 0.441 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.441 | |
| 3gxf | IFM | Glucosylceramidase | 3.2.1.45 | 0.441 | |
| 3ohf | 3HF | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.441 | |
| 3vcy | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.441 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.441 | |
| 4ey2 | 0RM | Metallo-beta-lactamase type 2 | / | 0.441 | |
| 4gh5 | NAD | Short-chain dehydrogenase/reductase SDR | / | 0.441 | |
| 4hfr | 14M | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.441 | |
| 4iao | APR | NAD-dependent histone deacetylase SIR2 | 3.5.1 | 0.441 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 4wq5 | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 5itz | LOC | Tubulin beta-2B chain | / | 0.441 | |
| 1d6w | 00R | Prothrombin | 3.4.21.5 | 0.440 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.440 | |
| 1hpx | KNI | Gag-Pol polyprotein | / | 0.440 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.440 | |
| 1ppm | 0P1 | Penicillopepsin-1 | 3.4.23.20 | 0.440 | |
| 1q20 | PLO | Sulfotransferase family cytosolic 2B member 1 | 2.8.2.2 | 0.440 | |
| 1sdw | IYT | Peptidyl-glycine alpha-amidating monooxygenase | 1.14.17.3 | 0.440 | |
| 1sze | 173 | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.440 | |
| 1vrq | FMN | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 1vrq | FMN | Subunit beta of sarcosine oxidase | / | 0.440 | |
| 1yhj | R6C | Pyridoxal kinase | 2.7.1.35 | 0.440 | |
| 1ypg | UIR | Prothrombin | 3.4.21.5 | 0.440 | |
| 2fdp | FRP | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2fzn | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.440 | |
| 2p4j | 23I | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2v2q | NVG | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.440 | |
| 2v3o | I26 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2v9j | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.440 | |
| 2xlp | FAD | Putative flavin-containing monooxygenase | / | 0.440 | |
| 2xpu | TDC | Tetracycline repressor protein class D | / | 0.440 | |
| 3buv | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.440 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.440 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.440 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.440 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.440 | |
| 3k5f | AYH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3ld6 | BCD | Lanosterol 14-alpha demethylase | 1.14.13.70 | 0.440 | |
| 3ohh | 3HH | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3qvx | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.440 | |
| 3six | GDP | Nodulation protein Z | / | 0.440 | |
| 3vrw | YS5 | Vitamin D3 receptor | / | 0.440 | |
| 4avg | SL6 | Polymerase acidic protein | / | 0.440 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.440 | |
| 4c7k | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 4dpf | 0LG | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4flh | 14K | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.440 | |
| 4j0y | 1H6 | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ocv | ANP | Aminoglycoside phosphotransferase | / | 0.440 | |
| 4tuv | CPZ | Cytochrome P450 119 | 1.14 | 0.440 | |
| 4xba | GMP | Aprataxin-like protein | 3 | 0.440 | |
| 5cpb | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 5k7u | SAM | N6-adenosine-methyltransferase 70 kDa subunit | / | 0.440 | |
| 3pbl | ETQ | D(3) dopamine receptor | / | 0.440 |