Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.26

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity		 Align
3gb2G3BGlycogen synthase kinase-3 beta2.7.11.261.000
4achKDIGlycogen synthase kinase-3 beta2.7.11.260.636
4acdGR9Glycogen synthase kinase-3 beta2.7.11.260.633
3f7z34OGlycogen synthase kinase-3 beta2.7.11.260.630
4acc7YGGlycogen synthase kinase-3 beta2.7.11.260.629
4afjSJJGlycogen synthase kinase-3 beta2.7.11.260.617
1q41IXMGlycogen synthase kinase-3 beta2.7.11.260.615
3du8553Glycogen synthase kinase-3 beta2.7.11.260.593
3l1sZ92Glycogen synthase kinase-3 beta2.7.11.260.592
4dit0KDGlycogen synthase kinase-3 beta2.7.11.260.592
4j711JXGlycogen synthase kinase-3 beta2.7.11.260.589
3i4bZ48Glycogen synthase kinase-3 beta2.7.11.260.588
4j1rI5RGlycogen synthase kinase-3 beta2.7.11.260.583
4acg6LQGlycogen synthase kinase-3 beta2.7.11.260.581
1pyxANPGlycogen synthase kinase-3 beta2.7.11.260.574
3sayOFTGlycogen synthase kinase-3 beta2.7.11.260.574
1uv5BRWGlycogen synthase kinase-3 beta2.7.11.260.571
3zrkZRKGlycogen synthase kinase-3 beta2.7.11.260.566
3zrmZRMGlycogen synthase kinase-3 beta2.7.11.260.565
1q3wATUGlycogen synthase kinase-3 beta2.7.11.260.564
3q3b55EGlycogen synthase kinase-3 beta2.7.11.260.563
1q5kTMUGlycogen synthase kinase-3 beta2.7.11.260.558
2hog710Serine/threonine-protein kinase Chk12.7.11.10.556
4b7tCWTGlycogen synthase kinase-3 beta2.7.11.260.551
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.548
3sd0TSKGlycogen synthase kinase-3 beta2.7.11.260.548
1q3dSTUGlycogen synthase kinase-3 beta2.7.11.260.543
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.540
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.539
4bf2STUMitogen-activated protein kinase kinase kinase 52.7.11.250.537
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.534
1j1cADPGlycogen synthase kinase-3 beta2.7.11.260.531
3f883HTGlycogen synthase kinase-3 beta2.7.11.260.531
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.531
4qmySTUSerine/threonine-protein kinase 242.7.11.10.527
4ftu7HKSerine/threonine-protein kinase Chk12.7.11.10.526
4ftt6HKSerine/threonine-protein kinase Chk12.7.11.10.524
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.523
1r0eDFNGlycogen synthase kinase-3 beta2.7.11.260.523
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.522
4fszHK8Serine/threonine-protein kinase Chk12.7.11.10.520
4ftr5HKSerine/threonine-protein kinase Chk12.7.11.10.520
4yzcSTUSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.519
3jxwLXGSerine/threonine-protein kinase pim-12.7.11.10.518
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.518
1nxkSTUMAP kinase-activated protein kinase 22.7.11.10.517
5dr9SKEAurora kinase A2.7.11.10.517
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.516
1nvrSTUSerine/threonine-protein kinase Chk12.7.11.10.515
4c62XWWTyrosine-protein kinase JAK2/0.514
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.512
2pvnP63Casein kinase II subunit alpha2.7.11.10.511
2h96893Mitogen-activated protein kinase 82.7.11.240.510
4jqeANPCasein kinase II subunit alpha2.7.11.10.510
3zdiUGJGlycogen synthase kinase-3 beta2.7.11.260.509
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.509
2ayp43ASerine/threonine-protein kinase Chk12.7.11.10.508
2ydiYDISerine/threonine-protein kinase Chk12.7.11.10.508
3eb0DRKUncharacterized protein/0.508
4nm0ADPGlycogen synthase kinase-3 beta2.7.11.260.508
3mfrANPPeripheral plasma membrane protein CASK2.7.11.10.507
3zrlZRLGlycogen synthase kinase-3 beta2.7.11.260.507
1wvxBD4Death-associated protein kinase 12.7.11.10.506
2wmqZYQSerine/threonine-protein kinase Chk12.7.11.10.505
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.505
4gmy0X5Tyrosine-protein kinase JAK2/0.505
2br1PFPSerine/threonine-protein kinase Chk12.7.11.10.504
2cdz23DSerine/threonine-protein kinase PAK 42.7.11.10.504
1okySTU3-phosphoinositide-dependent protein kinase 12.7.11.10.503
2gcdSTUSerine/threonine-protein kinase TAO22.7.11.10.503
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.503
4kikKSAInhibitor of nuclear factor kappa-B kinase subunit beta2.7.11.100.503
2dq7STUTyrosine-protein kinase Fyn2.7.10.20.501
2xj1XJ1Serine/threonine-protein kinase pim-12.7.11.10.501
4fswHK6Serine/threonine-protein kinase Chk12.7.11.10.501
4ftiH7KSerine/threonine-protein kinase Chk12.7.11.10.501
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.500
2ow3BIMGlycogen synthase kinase-3 beta2.7.11.260.500
4hyh1AMSerine/threonine-protein kinase Chk12.7.11.10.500
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.499
1zys199Serine/threonine-protein kinase Chk12.7.11.10.497
2ym6YM6Serine/threonine-protein kinase Chk12.7.11.10.497
4fstHK4Serine/threonine-protein kinase Chk12.7.11.10.497
4ft9H4KSerine/threonine-protein kinase Chk12.7.11.10.497
3mfsANPPeripheral plasma membrane protein CASK2.7.11.10.495
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.495
4nm7ADPGlycogen synthase kinase-3 beta2.7.11.260.494
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.494
1pkdUCNCyclin-dependent kinase 22.7.11.220.493
2gdo12CSerine/threonine-protein kinase Chk12.7.11.10.493
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.493
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.493
4aw1ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.493
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.493
4jboWPHAurora kinase A2.7.11.10.493
5auwQUEDeath-associated protein kinase 12.7.11.10.493
2cgw3C3Serine/threonine-protein kinase Chk12.7.11.10.492
2x8eX8ESerine/threonine-protein kinase Chk12.7.11.10.492
3zh8C58Protein kinase C iota type2.7.11.130.492
4bchT7ZCyclin-dependent kinase 92.7.11.220.492
1eh4IC1Casein kinase I homolog 12.7.11.10.491
1oiuN76Cyclin-dependent kinase 22.7.11.220.491
2dwbANPAurora kinase A2.7.11.10.491
2wmuZYUSerine/threonine-protein kinase Chk12.7.11.10.491
3ag9A02cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.491
3be9P04Casein kinase II subunit alpha2.7.11.10.491
4fsyHK7Serine/threonine-protein kinase Chk12.7.11.10.491
4hvh19RTyrosine-protein kinase JAK32.7.10.20.491
2c3lIDZSerine/threonine-protein kinase Chk12.7.11.10.490
2hxl422Serine/threonine-protein kinase Chk12.7.11.10.490
2i0ePDSProtein kinase C beta type2.7.11.130.490
2cchATPCyclin-dependent kinase 22.7.11.220.489
2nrySTUInterleukin-1 receptor-associated kinase 42.7.11.10.489
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.489
2wmwZYWSerine/threonine-protein kinase Chk12.7.11.10.489
2ydjYDJSerine/threonine-protein kinase Chk12.7.11.10.489
3bgpVX1Serine/threonine-protein kinase pim-12.7.11.10.489
3vf9477Tyrosine-protein kinase SYK2.7.10.20.489
4hvi19STyrosine-protein kinase JAK32.7.10.20.489
2broDF2Serine/threonine-protein kinase Chk12.7.11.10.488
2xa4AZ5Tyrosine-protein kinase JAK2/0.488
3vid4TTVascular endothelial growth factor receptor 22.7.10.10.488
4aguD15Cyclin-dependent kinase-like 1/0.488
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.488
4j97ACPFibroblast growth factor receptor 2/0.488
1h1wATP3-phosphoinositide-dependent protein kinase 12.7.11.10.487
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.487
2iw6QQ2Cyclin-dependent kinase 22.7.11.220.487
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.487
5e8xSTUTGF-beta receptor type-12.7.11.300.487
2j2iLY4Serine/threonine-protein kinase pim-12.7.11.10.486
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.486
4ftn2HKSerine/threonine-protein kinase Chk12.7.11.10.486
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.486
1stcSTUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.485
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.485
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.485
3ckxSTUSerine/threonine-protein kinase 242.7.11.10.485
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.485
4fl1ANPTyrosine-protein kinase SYK2.7.10.20.485
4oavACP2-5A-dependent ribonuclease3.1.260.485
4utdACPAurora kinase A2.7.11.10.485
5ackATP3-phosphoinositide-dependent protein kinase 12.7.11.10.485
2wmxZY6Serine/threonine-protein kinase Chk12.7.11.10.484
2x6dX6DAurora kinase A2.7.11.10.484
2xf04UBSerine/threonine-protein kinase Chk12.7.11.10.484
3tnwF18Cyclin-dependent kinase 22.7.11.220.484
4bcmT7ZCyclin-dependent kinase 22.7.11.220.484
4i22IREEpidermal growth factor receptor2.7.10.10.484
4wboANWRhodopsin kinase/0.484
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.483
2wmsZYSSerine/threonine-protein kinase Chk12.7.11.10.483
4erwSTUCyclin-dependent kinase 22.7.11.220.483
1jpaANPEphrin type-B receptor 22.7.10.10.482
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.482
3emg685Tyrosine-protein kinase SYK2.7.10.20.482
3iw4LW4Protein kinase C alpha type2.7.11.130.482
4bgg844Activin receptor type-12.7.11.300.482
4c02TAKActivin receptor type-12.7.11.300.482
4k1b1OCSerine/threonine-protein kinase pim-12.7.11.10.482
2vz6FEFCalcium/calmodulin-dependent protein kinase type II subunit alpha2.7.11.170.481
4hvg19QTyrosine-protein kinase JAK32.7.10.20.481
4mq22C4Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.481
5drdATPAurora kinase A2.7.11.10.481
5dt3ATPAurora kinase A2.7.11.10.481
1gih1PUCyclin-dependent kinase 22.7.11.220.480
2qo9ANPEphrin type-A receptor 32.7.10.10.480
3uo50BXAurora kinase A2.7.11.10.480
4ftaH5KSerine/threonine-protein kinase Chk12.7.11.10.480
2chlDKICasein kinase I isoform gamma-32.7.11.10.479
4dgo0JWCasein kinase II subunit alpha2.7.11.10.479
4qmzB49Serine/threonine-protein kinase 242.7.11.10.479
1lp4ANPCasein kinase II subunit alpha2.7.11.10.478
3a62STURibosomal protein S6 kinase beta-12.7.11.10.478
4fsnA58Serine/threonine-protein kinase Chk12.7.11.10.478
4ftm1HKSerine/threonine-protein kinase Chk12.7.11.10.478
4jbpYPHAurora kinase A2.7.11.10.478
5cu6ATPCasein kinase II subunit alpha2.7.11.10.478
1yvj4STTyrosine-protein kinase JAK32.7.10.20.477
2acxANPG protein-coupled receptor kinase 62.7.11.160.477
2csnCKICasein kinase I homolog 12.7.11.10.477
2qhn582Serine/threonine-protein kinase Chk12.7.11.10.477
2wmtZYTSerine/threonine-protein kinase Chk12.7.11.10.477
3hrcATP3-phosphoinositide-dependent protein kinase 12.7.11.10.477
3tkh07SSerine/threonine-protein kinase Chk12.7.11.10.477
4ftjH8KSerine/threonine-protein kinase Chk12.7.11.10.477
4wsqKSAAP2-associated protein kinase 12.7.11.10.477
2ittAEEEpidermal growth factor receptor2.7.10.10.476
3nunJMZ3-phosphoinositide-dependent protein kinase 12.7.11.10.476
3nuyJPZ3-phosphoinositide-dependent protein kinase 12.7.11.10.476
4dgmAGICasein kinase II subunit alpha2.7.11.10.476
1mq4ADPAurora kinase A2.7.11.10.475
1uvrBI83-phosphoinositide-dependent protein kinase 12.7.11.10.475
3mdvCL6Cholesterol 24-hydroxylase/0.475
3tucFPWTyrosine-protein kinase SYK2.7.10.20.475
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.475
1oecAA2Fibroblast growth factor receptor 2/0.474
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.474
2hy0306Serine/threonine-protein kinase Chk12.7.11.10.474
2ym5YM5Serine/threonine-protein kinase Chk12.7.11.10.474
3at3ATKCasein kinase II subunit alpha2.7.11.10.474
3umxQ18Serine/threonine-protein kinase pim-12.7.11.10.474
4dn5AGSMitogen-activated protein kinase kinase kinase 142.7.11.250.474
4ez50RSCyclin-dependent kinase 62.7.11.220.474
4qmxH8HSerine/threonine-protein kinase 242.7.11.10.474
1di8DTQCyclin-dependent kinase 22.7.11.220.473
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.473
3i60E86Mitogen-activated protein kinase 12.7.11.240.473
3vf80JETyrosine-protein kinase SYK2.7.10.20.473
4bcnT9NCyclin-dependent kinase 22.7.11.220.473
5dt4ATPAurora kinase A2.7.11.10.473
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.472
2xikJ60Serine/threonine-protein kinase 252.7.11.10.472
3cd3STUTyrosine-protein kinase Fes/Fps2.7.10.20.472
3rni21ZCyclin-dependent kinase 22.7.11.220.472
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.472
4jajXU1Aurora kinase A2.7.11.10.472
4xli1N1Abelson tyrosine-protein kinase 22.7.10.20.472
4yuqKS1Calmodulin-like domain protein kinase/0.472
1eioGCHGastrotropin/0.471
4g170VNCasein kinase I isoform gamma-32.7.11.10.471
4gfo0X2Non-receptor tyrosine-protein kinase TYK22.7.10.20.471
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.471
2hxq373Serine/threonine-protein kinase Chk12.7.11.10.470
2vd5BI8Myotonin-protein kinase2.7.11.10.470
2xru400Aurora kinase A2.7.11.10.470
3qcq3Q03-phosphoinositide-dependent protein kinase 12.7.11.10.470
4fjyFJYPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.470
4fz70VHTyrosine-protein kinase SYK2.7.10.20.470
4g160VMCasein kinase I isoform gamma-32.7.11.10.470
4g2fC07Ephrin type-A receptor 32.7.10.10.470
4ix6ADPUncharacterized protein/0.470
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.469
3cjgKIMVascular endothelial growth factor receptor 22.7.10.10.469
3gxlQIGTGF-beta receptor type-12.7.11.300.469
3mfuANPPeripheral plasma membrane protein CASK2.7.11.10.469
4bibIEOMitogen-activated protein kinase kinase kinase 52.7.11.250.469
4ckiADNProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.469
4fg7ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.469
4ftcH6KSerine/threonine-protein kinase Chk12.7.11.10.469
4grb0XGCasein kinase II subunit alpha2.7.11.10.469
4k181OBSerine/threonine-protein kinase pim-12.7.11.10.469
4nm5ADPGlycogen synthase kinase-3 beta2.7.11.260.469
4riyADPEpidermal growth factor receptor2.7.10.10.469
4y93746Tyrosine-protein kinase/0.469
1zrzBI1Protein kinase C iota type2.7.11.130.468
2vu3LZECyclin-dependent kinase 22.7.11.220.468
2ym7YM7Serine/threonine-protein kinase Chk12.7.11.10.468
3hrfATP3-phosphoinositide-dependent protein kinase 12.7.11.10.468
3ncgBK1Calmodulin-domain protein kinase 1, putative/0.468
3q9xEMOCasein kinase II subunit alpha2.7.11.10.468
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.468
4jia1K3Tyrosine-protein kinase JAK2/0.468
4qmnDB8Serine/threonine-protein kinase 242.7.11.10.468
5aacVGHALK tyrosine kinase receptor2.7.10.10.468
1yi3LY2Serine/threonine-protein kinase pim-12.7.11.10.467
2wihP48Cyclin-dependent kinase 22.7.11.220.467
2wxvWXVCyclin-dependent kinase 22.7.11.220.467
3bhh5CPCalcium/calmodulin-dependent protein kinase type II subunit beta2.7.11.170.467
3v8w0G2Tyrosine-protein kinase ITK/TSK2.7.10.20.467
4eok4SPCyclin-dependent kinase 22.7.11.220.467
4f081RSTyrosine-protein kinase JAK2/0.467
4fr4STUSerine/threonine-protein kinase 32A2.7.11.10.467
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.467
4hyi1AOSerine/threonine-protein kinase Chk12.7.11.10.467
2bujSTUSerine/threonine-protein kinase 16/0.466
2cgx3D3Serine/threonine-protein kinase Chk12.7.11.10.466
2y6o1N1Ephrin type-A receptor 42.7.10.10.466
3a60STURibosomal protein S6 kinase beta-12.7.11.10.466
3hx4ANPCalmodulin-domain protein kinase 1/0.466
3kn5ANPRibosomal protein S6 kinase alpha-52.7.11.10.466
4a06ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.466
4gfg0XFTyrosine-protein kinase SYK2.7.10.20.466
4n702HXSerine/threonine-protein kinase pim-12.7.11.10.466
1pyePM1Cyclin-dependent kinase 22.7.11.220.465
1qnfFADDeoxyribodipyrimidine photo-lyase4.1.99.30.465
2z97CAMCamphor 5-monooxygenase1.14.15.10.465
2zdt46CMitogen-activated protein kinase 102.7.11.240.465
3t8oATPRhodopsin kinase/0.465
4btkDTQTau-tubulin kinase 12.7.11.10.465
4gub0Y4Casein kinase II subunit alpha2.7.11.10.465
4jbqVX6Aurora kinase A2.7.11.10.465
4l521ULMitogen-activated protein kinase kinase kinase 72.7.11.250.465
1oi9N20Cyclin-dependent kinase 22.7.11.220.464
2xngA0HAurora kinase A2.7.11.10.464
2ym44YMSerine/threonine-protein kinase Chk12.7.11.10.464
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.464
4bdhWVISerine/threonine-protein kinase Chk22.7.11.10.464
4bznUGXSerine/threonine-protein kinase pim-12.7.11.10.464
4fob0USALK tyrosine kinase receptor2.7.10.10.464
4g3e0WCMitogen-activated protein kinase kinase kinase 142.7.11.250.464
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.464
4ks8B49Serine/threonine-protein kinase PAK 62.7.11.10.464
4lm5Q17Serine/threonine-protein kinase pim-12.7.11.10.464
1dawANPCasein kinase II subunit alpha2.7.11.10.463
1h1r6CPCyclin-dependent kinase 22.7.11.220.463
1j1bANPGlycogen synthase kinase-3 beta2.7.11.260.463
1uu8BI13-phosphoinositide-dependent protein kinase 12.7.11.10.463
2izt23DCasein kinase I isoform gamma-32.7.11.10.463
2p2h994Vascular endothelial growth factor receptor 22.7.10.10.463
3c4eC4ESerine/threonine-protein kinase pim-12.7.11.10.463
3ezrEZRCyclin-dependent kinase 22.7.11.220.463
3i5zZ48Mitogen-activated protein kinase 12.7.11.240.463
3sheI85MAP kinase-activated protein kinase 32.7.11.10.463
4fx360KCyclin-dependent kinase 22.7.11.220.463
4qmpDKISerine/threonine-protein kinase 242.7.11.10.463
5cshATPCasein kinase II subunit alpha2.7.11.10.463
1oguST8Cyclin-dependent kinase 22.7.11.220.462
1u54ACPActivated CDC42 kinase 1/0.462
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.462
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.462
3uli1N3Cyclin-dependent kinase 22.7.11.220.462
4ftlH0KSerine/threonine-protein kinase Chk12.7.11.10.462
4fv6E57Mitogen-activated protein kinase 12.7.11.240.462
4gk3L87Ephrin type-A receptor 32.7.10.10.462
1uu7BI23-phosphoinositide-dependent protein kinase 12.7.11.10.461
2brhDFWSerine/threonine-protein kinase Chk12.7.11.10.461
2c6eHPMAurora kinase A2.7.11.10.461
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.461
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.461
3oroAGSSerine/threonine protein kinase/0.461
4bcqTJFCyclin-dependent kinase 22.7.11.220.461
4dfrMTXDihydrofolate reductase1.5.1.30.461
4jr3KJREpidermal growth factor receptor2.7.10.10.461
4nj32KDCyclin-dependent kinase 22.7.11.220.461
1ke6LS2Cyclin-dependent kinase 22.7.11.220.460
1o6yACPSerine/threonine-protein kinase PknB2.7.11.10.460
2b7aIZATyrosine-protein kinase JAK2/0.460
4gih0X5Non-receptor tyrosine-protein kinase TYK22.7.10.20.460
4nka2K7Fibroblast growth factor receptor 1/0.460
4oauADP2-5A-dependent ribonuclease3.1.260.460
5dgzL20Serine/threonine-protein kinase pim-12.7.11.10.460
1oiyN41Cyclin-dependent kinase 22.7.11.220.459
3b8r887Vascular endothelial growth factor receptor 22.7.10.10.459
3igoANPCalmodulin-domain protein kinase 1, putative/0.459
3pjcPJCTyrosine-protein kinase JAK32.7.10.20.459
3vs5VSGTyrosine-protein kinase HCK2.7.10.20.459
4aojV4ZHigh affinity nerve growth factor receptor2.7.10.10.459
4flh14KPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
4kba1QMCasein kinase I isoform delta2.7.11.10.459
4o0sADNAurora kinase A2.7.11.10.459
4wo5324Serine/threonine-protein kinase B-raf2.7.11.10.459
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.458
2j0m4STFocal adhesion kinase 12.7.10.20.458
2objVRVSerine/threonine-protein kinase pim-12.7.11.10.458
2x2lX2LProto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.458
2ym3YM3Serine/threonine-protein kinase Chk12.7.11.10.458
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.458
3tea4CO4-hydroxybenzoyl-CoA thioesterase3.1.2.230.458
4c61LMMTyrosine-protein kinase JAK2/0.458
4f640S8Fibroblast growth factor receptor 1/0.458
4jrvKJVEpidermal growth factor receptor2.7.10.10.458
4oacADPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.458
1gij2PUCyclin-dependent kinase 22.7.11.220.457
1q97ATPSerine/threonine-protein kinase SKY12.7.11.10.457
2q9fC3SCholesterol 24-hydroxylase/0.457
2yexYEXSerine/threonine-protein kinase Chk12.7.11.10.457
3ddqRRCCyclin-dependent kinase 22.7.11.220.457
3vt7VDXVitamin D3 receptor/0.457
3w32W32Epidermal growth factor receptor2.7.10.10.457
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4bdiHAUSerine/threonine-protein kinase Chk22.7.11.10.457
4bl1ANPMaternal embryonic leucine zipper kinase2.7.11.10.457
4dgnLU2Casein kinase II subunit alpha2.7.11.10.457
4fg9ATPCalcium/calmodulin-dependent protein kinase type 12.7.11.170.457
4xumIMNPeroxisome proliferator-activated receptor gamma/0.457
2cgv3B3Serine/threonine-protein kinase Chk12.7.11.10.456
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.456
3uimANPBRASSINOSTEROID INSENSITIVE 1-associated receptor kinase 12.7.10.10.456
3zlyYSODual specificity mitogen-activated protein kinase kinase 12.7.12.20.456
4d9t0JGRibosomal protein S6 kinase alpha-32.7.11.10.456
4enxZ20Serine/threonine-protein kinase pim-12.7.11.10.456
4fsuHK5Serine/threonine-protein kinase Chk12.7.11.10.456
4k0y1OASerine/threonine-protein kinase pim-12.7.11.10.456
4n6z2HWSerine/threonine-protein kinase pim-12.7.11.10.456
2bheBRYCyclin-dependent kinase 22.7.11.220.455
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.455
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.455
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.455
3blrCPBCyclin-dependent kinase 92.7.11.220.455
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.455
3cy3JN5Serine/threonine-protein kinase pim-12.7.11.10.455
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.455
3hztJ60Calmodulin-like domain protein kinase isoform 3/0.455
3lfsA07Cyclin-dependent kinase 22.7.11.220.455
3qqkX02Cyclin-dependent kinase 22.7.11.220.455
3vsoEK1Peroxisome proliferator-activated receptor gamma/0.455
3w33W19Epidermal growth factor receptor2.7.10.10.455
4aotGW8Serine/threonine-protein kinase 102.7.11.10.455
4aw0ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.455
4fl3ANPTyrosine-protein kinase SYK2.7.10.20.455
4fv9E71Mitogen-activated protein kinase 12.7.11.240.455
4gk2L66Ephrin type-A receptor 32.7.10.10.455
4gvjADPNon-receptor tyrosine-protein kinase TYK22.7.10.20.455
4tuvCPZCytochrome P450 1191.140.455
5e8wSTUTGF-beta receptor type-12.7.11.300.455
1ol5ADPAurora kinase A2.7.11.10.454
2bdjHETProto-oncogene tyrosine-protein kinase Src2.7.10.20.454
2ejvNADL-threonine 3-dehydrogenase/0.454
2excJNKMitogen-activated protein kinase 102.7.11.240.454
2f2cAP9Cyclin-dependent kinase 62.7.11.220.454
2pvlP55Casein kinase II subunit alpha2.7.11.10.454
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.454
3gubGUBDeath-associated protein kinase 12.7.11.10.454
3qlg1N1Proto-oncogene tyrosine-protein kinase Src2.7.10.20.454
3vs7KS1Tyrosine-protein kinase HCK2.7.10.20.454
3w2sW2REpidermal growth factor receptor2.7.10.10.454
4anqVGHALK tyrosine kinase receptor2.7.10.10.454
4b99R4LMitogen-activated protein kinase 72.7.11.240.454
4qo9627Serine/threonine-protein kinase 242.7.11.10.454
1e9hINRCyclin-dependent kinase 22.7.11.220.453
1ke5LS1Cyclin-dependent kinase 22.7.11.220.453
1m78NDPDihydrofolate reductase1.5.1.30.453
1nytNAPShikimate dehydrogenase (NADP(+))/0.453
1ouk084Mitogen-activated protein kinase 14/0.453
1v1k3FPCyclin-dependent kinase 22.7.11.220.453
1yi4ADNSerine/threonine-protein kinase pim-12.7.11.10.453
2iw84SPCyclin-dependent kinase 22.7.11.220.453
2j7t274Serine/threonine-protein kinase 102.7.11.10.453
2of4979Tyrosine-protein kinase Lck2.7.10.20.453
2xyuQ9GEphrin type-A receptor 42.7.10.10.453
2yfxVGHALK tyrosine kinase receptor2.7.10.10.453
3s2pPMUCyclin-dependent kinase 22.7.11.220.453
3unj0BXCyclin-dependent kinase 22.7.11.220.453
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.453
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.453
1m2rMNYCasein kinase II subunit alpha2.7.11.10.452
1phgMYTCamphor 5-monooxygenase1.14.15.10.452
2c6tDT5Cyclin-dependent kinase 22.7.11.220.452
2wipP49Cyclin-dependent kinase 22.7.11.220.452
3gu6ADPDeath-associated protein kinase 12.7.11.10.452
3kljFADNADH-rubredoxin oxidoreductase1.18.1.10.452
3w0sANPHygromycin-B 4-O-kinase2.7.1.1630.452
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.452
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.452
4qmlANPSerine/threonine-protein kinase 242.7.11.10.452
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.452
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.451
1om1IQACasein kinase II subunit alpha2.7.11.10.451
2yn8STUEphrin type-B receptor 42.7.10.10.451
3nga3NGCasein kinase II subunit alpha2.7.11.10.451
3oom507Activin receptor type-12.7.11.300.451
3r7iX9ICyclin-dependent kinase 22.7.11.220.451
4bfmANPMaternal embryonic leucine zipper kinase2.7.11.10.451
4e4m0NHTyrosine-protein kinase JAK2/0.451
4ft3H1KSerine/threonine-protein kinase Chk12.7.11.10.451
1bygSTUTyrosine-protein kinase CSK/0.450
2b9fADPMitogen-activated protein kinase FUS32.7.11.240.450
2e9oA58Serine/threonine-protein kinase Chk12.7.11.10.450
2j0j4STFocal adhesion kinase 12.7.10.20.450
2uzlC94Cyclin-dependent kinase 22.7.11.220.450
3ma301ISerine/threonine-protein kinase pim-12.7.11.10.450
3qtwX3ACyclin-dependent kinase 22.7.11.220.450
3zewSTUEphrin type-B receptor 42.7.10.10.450
4c34STUcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
4dpuAGSMevalonate diphosphate decarboxylase/0.450
4ix4ADPUncharacterized protein/0.450
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.450
1xwsBI1Serine/threonine-protein kinase pim-12.7.11.10.449
2b55D31Cyclin-dependent kinase 22.7.11.220.449
2py3ACPFibroblast growth factor receptor 2/0.449
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.449
3cxw7CPSerine/threonine-protein kinase pim-12.7.11.10.449
3ezvEZVCyclin-dependent kinase 22.7.11.220.449
3lctADPALK tyrosine kinase receptor2.7.10.10.449
3qaqQAQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
3vs6VSHTyrosine-protein kinase HCK2.7.10.20.449
3zdu38RCyclin-dependent kinase-like 32.7.11.220.449
4f1sF1SPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
4fuxE75Mitogen-activated protein kinase 12.7.11.240.449
4i0r1B4Tyrosine-protein kinase SYK2.7.10.20.449
5av2KMPDeath-associated protein kinase 12.7.11.10.449
1finATPCyclin-dependent kinase 22.7.11.220.448
1x2hLPALipoate-protein ligase A6.3.1.200.448
2bhhRYUCyclin-dependent kinase 22.7.11.220.448
2e9p77ASerine/threonine-protein kinase Chk12.7.11.10.448
2wtdZZKSerine/threonine-protein kinase Chk22.7.11.10.448
2yitYITSerine/threonine-protein kinase Chk22.7.11.10.448
3c7qXINVascular endothelial growth factor receptor 22.7.10.10.448
3cjfSAVVascular endothelial growth factor receptor 22.7.10.10.448
3gwfFADCyclohexanone monooxygenase/0.448
3k5uPFQAurora kinase A2.7.11.10.448
4ansVGHALK tyrosine kinase receptor2.7.10.10.448
4bdcODHSerine/threonine-protein kinase Chk22.7.11.10.448
4bgh3I6Cyclin-dependent kinase 22.7.11.220.448
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.448
4fto3HKSerine/threonine-protein kinase Chk12.7.11.10.448
4h4qFADBiphenyl dioxygenase ferredoxin reductase subunit/0.448
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.448
4yhjAN2G protein-coupled receptor kinase 42.7.11.160.448
5dosATPAurora kinase A2.7.11.10.448
1ol7ADPAurora kinase A2.7.11.10.447
1rx1NAPDihydrofolate reductase1.5.1.30.447
1ykdCMPAdenylate cyclase/0.447
2bkzSBCCyclin-dependent kinase 22.7.11.220.447
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.447
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.447
2pe039Z3-phosphoinositide-dependent protein kinase 12.7.11.10.447
2pvmP29Casein kinase II subunit alpha2.7.11.10.447
2wtcVGMSerine/threonine-protein kinase Chk22.7.11.10.447
2yerTQ1Serine/threonine-protein kinase Chk12.7.11.10.447
3at4CCKCasein kinase II subunit alpha2.7.11.10.447
3m42HGFMAP kinase-activated protein kinase 22.7.11.10.447
3nux3NVCyclin-dependent kinase 62.7.11.220.447
3sqq99ZCyclin-dependent kinase 22.7.11.220.447
3umw596Serine/threonine-protein kinase pim-12.7.11.10.447
3w1f1O5Dual specificity protein kinase TTK2.7.12.10.447
4b4oNDPEpimerase family protein SDR39U1/0.447
4cd2FOLDihydrofolate reductase1.5.1.30.447
4dfn0K1Tyrosine-protein kinase SYK2.7.10.20.447
4dquNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
4nb6444Nuclear receptor ROR-gamma/0.447
4qpmADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.447
1ke7LS3Cyclin-dependent kinase 22.7.11.220.446
1pmeSB2Mitogen-activated protein kinase 12.7.11.240.446
1s3vTQDDihydrofolate reductase1.5.1.30.446
2btsU32Cyclin-dependent kinase 22.7.11.220.446
2ckeIQUDeath-associated protein kinase 2/0.446
2eufLQQCyclin-dependent kinase 62.7.11.220.446
2itpAEEEpidermal growth factor receptor2.7.10.10.446
2vuw5IDSerine/threonine-protein kinase haspin2.7.11.10.446
3bqr4RBDeath-associated protein kinase 3/0.446
3f46I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.446
3js2VM1Fibroblast growth factor receptor 1/0.446
3ofm4B0Casein kinase II subunit alpha'2.7.11.10.446
3rmf20ZCyclin-dependent kinase 22.7.11.220.446
3t3r9PLCytochrome P450 2A61.14.130.446
4b0gVEKAurora kinase A2.7.11.10.446
4e730NRMitogen-activated protein kinase 82.7.11.240.446
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.446
4kbc1QJCasein kinase I isoform delta2.7.11.10.446
4o0wADNAurora kinase A2.7.11.10.446
4qnaX11Serine/threonine-protein kinase 242.7.11.10.446
5dn3ATPAurora kinase A2.7.11.10.446
1a72PADAlcohol dehydrogenase E chain1.1.1.10.445
1dhjMTXDihydrofolate reductase1.5.1.30.445
1draMTXDihydrofolate reductase1.5.1.30.445
1fwkADPHomoserine kinase2.7.1.390.445
1ol6ATPAurora kinase A2.7.11.10.445
2izuP01Casein kinase I isoform gamma-32.7.11.10.445
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.445
2xm9LWHSerine/threonine-protein kinase Chk22.7.11.10.445
3a7hATPSerine/threonine-protein kinase 242.7.11.10.445
3icsADPCoenzyme A disulfide reductase/0.445
3mtfA3FActivin receptor type-12.7.11.300.445
3qk0QK0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.445
3qu0X40Cyclin-dependent kinase 22.7.11.220.445
3s4qNK0Mitogen-activated protein kinase 14/0.445
3u8w09JMitogen-activated protein kinase 14/0.445
3vjoANPEpidermal growth factor receptor2.7.10.10.445
3w0oADPHygromycin-B 4-O-kinase2.7.1.1630.445
3w0qANPHygromycin-B 4-O-kinase2.7.1.1630.445
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.444
1zeoC01Peroxisome proliferator-activated receptor gamma/0.444
2cppCAMCamphor 5-monooxygenase1.14.15.10.444
2itzIREEpidermal growth factor receptor2.7.10.10.444
2j2pSC2Ficolin-2/0.444
2pe24643-phosphoinositide-dependent protein kinase 12.7.11.10.444
2xb7GUIALK tyrosine kinase receptor2.7.10.10.444
2xizXIZSerine/threonine-protein kinase pim-12.7.11.10.444
3efwAK8Aurora kinase A2.7.11.10.444
3lcdBDYMacrophage colony-stimulating factor 1 receptor2.7.10.10.444
3qcy3Q33-phosphoinositide-dependent protein kinase 12.7.11.10.444
3s2a2NQPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.444
3zxtACPDeath-associated protein kinase 12.7.11.10.444
4ct2ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.444
4ez30S0Cyclin-dependent kinase 22.7.11.220.444
4mf029ZTyrosine-protein kinase ITK/TSK2.7.10.20.444
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
4nks2M2Fibroblast growth factor receptor 1/0.444
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.444
5d12G97Proto-oncogene tyrosine-protein kinase Src2.7.10.20.444
1mvsDTMDihydrofolate reductase1.5.1.30.443
1p2a5BNCyclin-dependent kinase 22.7.11.220.443
1xjdSTUProtein kinase C theta type2.7.11.130.443
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.443
2i40BLZCyclin-dependent kinase 22.7.11.220.443
2in6839Wee1-like protein kinase2.7.10.20.443
2vtnLZ7Cyclin-dependent kinase 22.7.11.220.443
2w05FRTCyclin-dependent kinase 22.7.11.220.443
2w1eL0EAurora kinase A2.7.11.10.443
3dafFEG5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.443
3r9hZ67Cyclin-dependent kinase 22.7.11.220.443
3s1h56ZCyclin-dependent kinase 22.7.11.220.443
3u9eCOALmo1369 protein/0.443
3vs4VSFTyrosine-protein kinase HCK2.7.10.20.443
4hni16WCasein kinase I isoform epsilon2.7.11.10.443
4ic7ANPMitogen-activated protein kinase 72.7.11.240.443
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.443
4jq7KJQEpidermal growth factor receptor2.7.10.10.443
4k5p1OSM1 family aminopeptidase3.4.110.443
4mbl26LSerine/threonine-protein kinase pim-12.7.11.10.443
4uyaAGSMitogen-activated protein kinase kinase kinase 212.7.11.250.443
1iwiCAMCamphor 5-monooxygenase1.14.15.10.442
2c3iIYZSerine/threonine-protein kinase pim-12.7.11.10.442
2j9mPY8Cyclin-dependent kinase 22.7.11.220.442
2qo7ANPEphrin type-A receptor 32.7.10.10.442
2qoqANPEphrin type-A receptor 32.7.10.10.442
2x9fX9FEphrin type-B receptor 42.7.10.10.442
2ycqUPXSerine/threonine-protein kinase Chk22.7.11.10.442
3b2tM33Fibroblast growth factor receptor 2/0.442
3c50ADPRhodopsin kinase/0.442
3ggfGVDSerine/threonine-protein kinase 26/0.442
3ormAGSSerine/threonine protein kinase/0.442
3zu2NAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.442
4bzo676Serine/threonine-protein kinase pim-12.7.11.10.442
4cd0AWJALK tyrosine kinase receptor2.7.10.10.442
4cfnJYMCyclin-dependent kinase 22.7.11.220.442
4hyu1BKMitogen-activated protein kinase 82.7.11.240.442
4x5jFOLDihydrofolate reductase1.5.1.30.442
1iwjCAMCamphor 5-monooxygenase1.14.15.10.441
1rx8NAPDihydrofolate reductase1.5.1.30.441
1v0oINRCell division control protein 2 homolog2.7.11.220.441
2btrU73Cyclin-dependent kinase 22.7.11.220.441
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.441
2itqITQEpidermal growth factor receptor2.7.10.10.441
2pe15173-phosphoinositide-dependent protein kinase 12.7.11.10.441
2pziAXXSerine/threonine-protein kinase PknG2.7.11.10.441
2qocANPEphrin type-A receptor 32.7.10.10.441
2xp2VGHALK tyrosine kinase receptor2.7.10.10.441
2zv2609Calcium/calmodulin-dependent protein kinase kinase 22.7.11.170.441
3bhy7CPDeath-associated protein kinase 3/0.441
3opdHIEHeat shock protein 83/0.441
3wi6YRZMAP kinase-activated protein kinase 22.7.11.10.441
4bdfH3RSerine/threonine-protein kinase Chk22.7.11.10.441
4bdgP3JSerine/threonine-protein kinase Chk22.7.11.10.441
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.441
4fz60VGTyrosine-protein kinase SYK2.7.10.20.441
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.441
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1m2pHNACasein kinase II subunit alpha2.7.11.10.440
1w0xOLOCyclin-dependent kinase 22.7.11.220.440
2iw94SPCyclin-dependent kinase 22.7.11.220.440
2j0k4STFocal adhesion kinase 12.7.10.20.440
2pmoHMDProtein kinase 7/0.440
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.440
3ddpRC8Cyclin-dependent kinase 22.7.11.220.440
3g45988cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
3qtzX42Cyclin-dependent kinase 22.7.11.220.440
3rpv26ZCyclin-dependent kinase 22.7.11.220.440
3th8TH9Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.440
3w16P9JAurora kinase A2.7.11.10.440
3zc6VFCTyrosine-protein kinase JAK32.7.10.20.440
4erkOLOMitogen-activated protein kinase 12.7.11.240.440
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.440
4k33ACPFibroblast growth factor receptor 32.7.10.10.440
4lopSB4Mitogen-activated protein kinase 14/0.440
4o0rX4ZSerine/threonine-protein kinase PAK 12.7.11.10.440
4o0uADNAurora kinase A2.7.11.10.440
5dt0SKEAurora kinase A2.7.11.10.440
5hes032Mitogen-activated protein kinase kinase kinase 202.7.11.250.440