sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 4mzx | TZD | Benzoylformate decarboxylase | 4.1.1.7 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 4mzx | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 1.000 | |
| 4qel | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.757 | |
| 1bfd | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.677 | |
| 4gm4 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.627 | |
| 4jd5 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.625 | |
| 5dgt | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.618 | |
| 4ju8 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.612 | |
| 2fwn | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.610 | |
| 4k9p | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.603 | |
| 4mpr | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.587 | |
| 4jub | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.586 | |
| 1po7 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.584 | |
| 4ju9 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.582 | |
| 4juf | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.581 | |
| 4juc | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.576 | |
| 4k9o | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.576 | |
| 4k9n | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.573 | |
| 1mcz | TDP | Benzoylformate decarboxylase | 4.1.1.7 | 0.557 | |
| 3fzn | D7K | Benzoylformate decarboxylase | 4.1.1.7 | 0.554 | |
| 2v3w | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.552 | |
| 4gg1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.550 | |
| 4mq5 | TPP | Benzoylformate decarboxylase | 4.1.1.7 | 0.536 | |
| 3keu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.530 | |
| 4gm0 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.530 | |
| 1pox | TPP | Pyruvate oxidase | 1.2.3.3 | 0.526 | |
| 4mpp | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.523 | |
| 2ez9 | TDK | Pyruvate oxidase | 1.2.3.3 | 0.520 | |
| 3fhy | ATP | Pyridoxal kinase | 2.7.1.35 | 0.513 | |
| 2o1x | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.501 | |
| 3i5x | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.501 | |
| 3oib | FDA | Putative acyl-CoA dehydrogenase | / | 0.501 | |
| 5dld | UD1 | UDP-N-Acetylglucosamine 2-epimerase | / | 0.500 | |
| 2q5o | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.499 | |
| 3zbr | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.496 | |
| 4is3 | NAD | 3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 2 | 1.17.98.1 | 0.495 | |
| 4qe6 | JN3 | Bile acid receptor | / | 0.495 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.494 | |
| 4fj2 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.494 | |
| 4zp1 | TPP | Pyruvate decarboxylase | 4.1.1.1 | 0.494 | |
| 1pow | TPP | Pyruvate oxidase | 1.2.3.3 | 0.493 | |
| 2uuv | FAD | Alkyldihydroxyacetonephosphate synthase | 2.5.1.26 | 0.492 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.491 | |
| 2ooy | ATP | 5'-AMP-activated protein kinase subunit gamma | / | 0.490 | |
| 4gm1 | TZD | Benzoylformate decarboxylase | 4.1.1.7 | 0.490 | |
| 2yut | NAP | Putative short-chain oxidoreductase | / | 0.489 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.489 | |
| 2cts | COA | Citrate synthase, mitochondrial | 2.3.3.1 | 0.488 | |
| 6cts | CIC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.488 | |
| 3gbu | ATP | Uncharacterized sugar kinase PH1459 | 2.7.1 | 0.487 | |
| 4iac | ACP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.487 | |
| 4m99 | ACO | UDP-N-acetylgalactosaminyltransferase | / | 0.486 | |
| 4uug | PXG | Branched-chain amino acid aminotransferase, putative | / | 0.486 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.485 | |
| 4nu6 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.485 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.484 | |
| 2vhx | NAD | Alanine dehydrogenase | 1.4.1.1 | 0.484 | |
| 3dey | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.484 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.484 | |
| 3klm | DHT | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.484 | |
| 5cts | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.484 | |
| 2ch6 | ADP | N-acetyl-D-glucosamine kinase | 2.7.1.59 | 0.483 | |
| 1kqw | RTL | Cellular retinol-binding protein type II | / | 0.482 | |
| 3ieu | GDP | GTPase Era | / | 0.482 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.482 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.482 | |
| 2vhw | NAI | Alanine dehydrogenase | 1.4.1.1 | 0.481 | |
| 3nxx | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.481 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.481 | |
| 1e4g | ATP | Cell division protein FtsA | / | 0.480 | |
| 2eba | FAD | Putative glutaryl-CoA dehydrogenase | / | 0.480 | |
| 1in5 | ADP | Holliday junction ATP-dependent DNA helicase RuvB | / | 0.479 | |
| 1kqu | BR4 | Phospholipase A2, membrane associated | / | 0.479 | |
| 1pjk | ANP | Casein kinase II subunit alpha | 2.7.11.1 | 0.479 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.479 | |
| 3eof | FMN | Putative oxidase | / | 0.479 | |
| 3g49 | NAP | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.479 | |
| 3iqh | TYR_ASP_ILE | Cysteine synthase | 2.5.1.47 | 0.479 | |
| 4ozt | P1A | Ecdysone receptor, putative | / | 0.479 | |
| 1ofg | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.478 | |
| 2gnh | H52 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.478 | |
| 2j3i | NAP | NADPH-dependent oxidoreductase 2-alkenal reductase | 1.3.1.74 | 0.478 | |
| 2yxu | ATP | Pyridoxal kinase | 2.7.1.35 | 0.478 | |
| 3q43 | D66 | M1 family aminopeptidase | 3.4.11 | 0.478 | |
| 4a2b | AGS | Cell division protein FtsA | / | 0.478 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.478 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.477 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.477 | |
| 1q3q | ANP | Thermosome subunit alpha | / | 0.477 | |
| 2ezt | TDM | Pyruvate oxidase | 1.2.3.3 | 0.477 | |
| 3ibd | CPZ | Cytochrome P450 2B6 | 1.14.13 | 0.477 | |
| 1esv | LAR | Actin, alpha skeletal muscle | / | 0.476 | |
| 1fdt | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.476 | |
| 1got | GDP | Guanine nucleotide-binding protein G(t) subunit alpha-1 | / | 0.476 | |
| 4id5 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.476 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.476 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.475 | |
| 1ve3 | SAM | Uncharacterized protein | / | 0.475 | |
| 3jzd | NAD | Maleylacetate reductase | / | 0.475 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.475 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.475 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.475 | |
| 5dbg | NAD | Iridoid synthase | 1.3.1.99 | 0.475 | |
| 1f0x | FAD | D-lactate dehydrogenase | 1.1.1.28 | 0.474 | |
| 2fhl | BNI | Avidin-related protein 4/5 | / | 0.474 | |
| 2qo4 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.474 | |
| 2y05 | NAP | Prostaglandin reductase 1 | / | 0.474 | |
| 1w5s | ADP | ORC1-type DNA replication protein 2 | / | 0.473 | |
| 2q5q | TPW | Indole-3-pyruvate decarboxylase | 4.1.1.74 | 0.473 | |
| 3lpk | Z76 | Beta-secretase 1 | 3.4.23.46 | 0.473 | |
| 3qwf | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.473 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.473 | |
| 4bby | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.473 | |
| 4oh4 | ANP | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.473 | |
| 5esd | TDP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.473 | |
| 1f8s | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.472 | |
| 1zth | ADP | RIO-type serine/threonine-protein kinase Rio1 | 2.7.11.1 | 0.472 | |
| 3v0o | 4GW | Histo-blood group ABO system transferase | / | 0.472 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.472 | |
| 4xw4 | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.472 | |
| 5ftf | ADP | TPR domain protein | / | 0.472 | |
| 2bhi | SFT | Cytotoxin 3 | / | 0.471 | |
| 3dbv | NAD | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.471 | |
| 3ix3 | OHN | Transcriptional activator protein LasR | / | 0.471 | |
| 4n3c | UD1 | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.471 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.470 | |
| 1yb5 | NAP | Quinone oxidoreductase | 1.6.5.5 | 0.470 | |
| 2y0m | ACO | Histone acetyltransferase KAT8 | / | 0.470 | |
| 3flk | NAI | Tartrate dehydrogenase/decarboxylase | 1.1.1.93 | 0.470 | |
| 3l0l | HC3 | Nuclear receptor ROR-gamma | / | 0.470 | |
| 3toh | 079 | Gag-Pol polyprotein | 2.7.7.49 | 0.470 | |
| 3x2w | ATP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.470 | |
| 4iqg | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.470 | |
| 4ng5 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.470 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.470 | |
| 1ot7 | IU5 | Bile acid receptor | / | 0.469 | |
| 1u3c | FAD | Cryptochrome-1 | / | 0.469 | |
| 1vdc | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.469 | |
| 1y3a | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.469 | |
| 2jlc | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.469 | |
| 2tps | TPS | Thiamine-phosphate synthase | / | 0.469 | |
| 2xpv | MIY | Tetracycline repressor protein class D | / | 0.469 | |
| 3gqv | NAP | Enoyl reductase LovC | 1 | 0.469 | |
| 1s19 | MC9 | Vitamin D3 receptor | / | 0.468 | |
| 1u1j | C2F | 5-methyltetrahydropteroyltriglutamate--homocysteine methyltransferase 1 | 2.1.1.14 | 0.468 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.468 | |
| 3pgi | F41 | Endothiapepsin | 3.4.23.22 | 0.468 | |
| 4ejm | NAP | Putative zinc-binding dehydrogenase | / | 0.468 | |
| 4eu5 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.468 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.468 | |
| 4hjo | AQ4 | Epidermal growth factor receptor | 2.7.10.1 | 0.468 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.467 | |
| 1rfv | ADP | Pyridoxal kinase | 2.7.1.35 | 0.467 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.467 | |
| 2iya | ZIO | Oleandomycin glycosyltransferase | / | 0.467 | |
| 3dl0 | AP5 | Adenylate kinase | / | 0.467 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.467 | |
| 3mdd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.467 | |
| 3q44 | D50 | M1 family aminopeptidase | 3.4.11 | 0.467 | |
| 4da0 | GNG | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.467 | |
| 4olf | HFG | Proline--tRNA ligase | 6.1.1.15 | 0.467 | |
| 1f8g | NAD | NAD(P) transhydrogenase subunit alpha part 1 | 1.6.1.2 | 0.466 | |
| 1g4t | FTP | Thiamine-phosphate synthase | / | 0.466 | |
| 1rye | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.466 | |
| 1std | BFS | Scytalone dehydratase | 4.2.1.94 | 0.466 | |
| 1y5r | C0R | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.466 | |
| 2gs9 | SAH | Uncharacterized protein | / | 0.466 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.466 | |
| 3ioc | A5D | Pantothenate synthetase | 6.3.2.1 | 0.466 | |
| 4ki8 | ADP | 60 kDa chaperonin | / | 0.466 | |
| 4nmd | FDA | Bifunctional protein PutA | / | 0.466 | |
| 4uir | FAD | Oleate hydratase | 4.2.1.53 | 0.466 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.466 | |
| 2jih | 097 | A disintegrin and metalloproteinase with thrombospondin motifs 1 | 3.4.24 | 0.465 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.465 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.465 | |
| 3n6m | GTP | Genome polyprotein | / | 0.465 | |
| 3u33 | FAD | Putative acyl-CoA dehydrogenase AidB | 1.3.99 | 0.465 | |
| 4en4 | ATP | Pyridoxal kinase | 2.7.1.35 | 0.465 | |
| 4fj0 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.465 | |
| 4frk | DWD | Beta-secretase 1 | 3.4.23.46 | 0.465 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.465 | |
| 4wdg | A2P | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.465 | |
| 1g67 | TZP | Thiamine-phosphate synthase | / | 0.464 | |
| 1nje | DCM | Thymidylate synthase | / | 0.464 | |
| 1vcf | FMN | Isopentenyl-diphosphate delta-isomerase | / | 0.464 | |
| 2c0o | L2G | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.464 | |
| 2pan | TDP | Glyoxylate carboligase | 4.1.1.47 | 0.464 | |
| 2pxa | SAH | Genome polyprotein | 2.7.7.48 | 0.464 | |
| 2rc3 | NAD | CBS domain | / | 0.464 | |
| 3lgp | 50X | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.464 | |
| 3lpi | Z74 | Beta-secretase 1 | 3.4.23.46 | 0.464 | |
| 3p4t | FAO | Putative acyl-CoA dehydrogenase | / | 0.464 | |
| 3qm4 | PN0 | Cytochrome P450 2D6 | / | 0.464 | |
| 3ruq | ADP | Chaperonin | / | 0.464 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.464 | |
| 4mv8 | ACP | Biotin carboxylase | 6.3.4.14 | 0.464 | |
| 4y9l | FAD | Acyl-CoA dehydrogenase family member 11 | / | 0.464 | |
| 5kj1 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.464 | |
| 1e7q | NAP | GDP-L-fucose synthase | / | 0.463 | |
| 1j1z | ATP | Argininosuccinate synthase | / | 0.463 | |
| 1x7g | NAP | Putative ketoacyl reductase | 1.3.1 | 0.463 | |
| 3ey4 | 352 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.463 | |
| 3fqk | 79Z | Genome polyprotein | 2.7.7.48 | 0.463 | |
| 3ixk | 929 | Beta-secretase 1 | 3.4.23.46 | 0.463 | |
| 3pfd | FDA | Acyl-CoA dehydrogenase FadE25 | / | 0.463 | |
| 4dfg | 0JV | Gag-Pol polyprotein | 3.4.23.16 | 0.463 | |
| 4fj1 | NAP | 17beta-hydroxysteroid dehydrogenase | / | 0.463 | |
| 4fkz | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.463 | |
| 4geb | 0LD | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.463 | |
| 4h4y | NAP | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.463 | |
| 4kqw | NAP | Ketol-acid reductoisomerase (NADP(+)) | / | 0.463 | |
| 4nu5 | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.463 | |
| 1fdu | NAP | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.462 | |
| 1q0z | AKA | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.462 | |
| 1upc | TPP | N(2)-(2-carboxyethyl)arginine synthase | / | 0.462 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.462 | |
| 2e98 | B29 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.462 | |
| 2eg5 | SAH | 7-methylxanthosine synthase 1 | / | 0.462 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.462 | |
| 2wa2 | SAM | Genome polyprotein | / | 0.462 | |
| 2xvq | 9DS | Serum albumin | / | 0.462 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.462 | |
| 3sp6 | IL2 | Peroxisome proliferator-activated receptor alpha | / | 0.462 | |
| 3sqw | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.462 | |
| 4ku5 | DCC | 3-oxoacyl-[ACP] synthase III | / | 0.462 | |
| 1e81 | M91 | Endothiapepsin | 3.4.23.22 | 0.461 | |
| 1juv | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.461 | |
| 1mja | COA | Histone acetyltransferase ESA1 | / | 0.461 | |
| 1n2e | APC | Pantothenate synthetase | 6.3.2.1 | 0.461 | |
| 1q0r | AKT | Aclacinomycin methylesterase RdmC | 3.1.1.95 | 0.461 | |
| 1wuu | ANP | Galactokinase | 2.7.1.6 | 0.461 | |
| 1xu7 | CPS | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.461 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.461 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.461 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.461 | |
| 2klh | 5GP | 2'-deoxynucleoside 5'-phosphate N-hydrolase 1 | / | 0.461 | |
| 3eks | CY9 | Actin-5C | / | 0.461 | |
| 3ha5 | SFG | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.461 | |
| 3ums | GDP | Guanine nucleotide-binding protein G(i) subunit alpha-1 | / | 0.461 | |
| 3uyk | 0CX | Probable NDP-rhamnosyltransferase | / | 0.461 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.461 | |
| 4fiz | CUE | 17beta-hydroxysteroid dehydrogenase | / | 0.461 | |
| 4gah | 0ET | Acyl-coenzyme A thioesterase THEM4 | 3.1.2.2 | 0.461 | |
| 4hai | I23 | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.461 | |
| 4o7n | ADP | Phosphoribosylaminoimidazole-succinocarboxamide synthase | 6.3.2.6 | 0.461 | |
| 4wlu | NAD | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.461 | |
| 5c3a | URM | Histo-blood group ABO system transferase | / | 0.461 | |
| 1csc | CMC | Citrate synthase, mitochondrial | 2.3.3.1 | 0.460 | |
| 1jmf | UMP | Thymidylate synthase | / | 0.460 | |
| 1jqi | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | / | 0.460 | |
| 1m4d | COA | Aminoglycoside 2'-N-acetyltransferase | 2.3.1 | 0.460 | |
| 1udy | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.460 | |
| 1xkv | ATP | Phosphoenolpyruvate carboxykinase (ATP) | / | 0.460 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.460 | |
| 2npa | MMB | Peroxisome proliferator-activated receptor alpha | / | 0.460 | |
| 2wp9 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.460 | |
| 2wp9 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.460 | |
| 2xvu | 9DN | Serum albumin | / | 0.460 | |
| 2zev | B71 | Geranylgeranyl pyrophosphate synthase | / | 0.460 | |
| 3b6z | CO7 | Enoyl reductase LovC | 1 | 0.460 | |
| 3byz | H11 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3f6s | FMN | Flavodoxin | / | 0.460 | |
| 3ll9 | ADP | Isopentenyl phosphate kinase | / | 0.460 | |
| 3orz | BI4 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.460 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.460 | |
| 3w8w | FAD | Putative FAD-dependent oxygenase EncM | / | 0.460 | |
| 5ap7 | SVE | Dual specificity protein kinase TTK | 2.7.12.1 | 0.460 | |
| 5iqi | GNP | Bifunctional AAC/APH | 2.3.1 | 0.460 | |
| 1dfo | FFO | Serine hydroxymethyltransferase | 2.1.2.1 | 0.459 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.459 | |
| 2daa | DCS | D-alanine aminotransferase | 2.6.1.21 | 0.459 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.459 | |
| 2nnl | NAP | Dihydroflavonol 4-reductase | 1.1.1.219 | 0.459 | |
| 2x7j | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.459 | |
| 2znn | S44 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 3dhe | AND | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.459 | |
| 3elu | SAM | Methyltransferase | / | 0.459 | |
| 3qlh | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 3tfp | 03L | Dehydrosqualene synthase | / | 0.459 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.459 | |
| 4bcr | WY1 | Peroxisome proliferator-activated receptor alpha | / | 0.459 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.459 | |
| 4h6r | FDA | Proline dehydrogenase | / | 0.459 | |
| 4ia7 | BIV | Vitamin D3 receptor A | / | 0.459 | |
| 4irn | FAD | AnaB | / | 0.459 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.459 | |
| 4rrg | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.459 | |
| 4xgx | ADP | FAD:protein FMN transferase | / | 0.459 | |
| 4xyb | NDP | Formate dehydrogenase | / | 0.459 | |
| 1boo | SAH | Modification methylase PvuII | 2.1.1.113 | 0.458 | |
| 1e94 | ANP | ATP-dependent protease ATPase subunit HslU | / | 0.458 | |
| 1lke | DOG | Bilin-binding protein | / | 0.458 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.458 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.458 | |
| 2ojt | UBA | Glutamate receptor ionotropic, kainate 1 | / | 0.458 | |
| 2ou2 | ACO | Histone acetyltransferase KAT5 | / | 0.458 | |
| 2q0k | NAP | Thioredoxin reductase | 1.8.1.9 | 0.458 | |
| 3etd | NDP | Glutamate dehydrogenase 1, mitochondrial | 1.4.1.3 | 0.458 | |
| 3t88 | S0N | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.458 | |
| 3up0 | D7S | aceDAF-12 | / | 0.458 | |
| 4ge7 | 0K5 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.458 | |
| 4n9w | GDP | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.458 | |
| 4qtu | SAM | 18S rRNA (guanine(1575)-N(7))-methyltransferase | / | 0.458 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.458 | |
| 1d3h | A26 | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.457 | |
| 1db1 | VDX | Vitamin D3 receptor | / | 0.457 | |
| 1dig | L37 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.457 | |
| 1f20 | NAP | Nitric oxide synthase, brain | 1.14.13.39 | 0.457 | |
| 1ig1 | ANP | Death-associated protein kinase 1 | 2.7.11.1 | 0.457 | |
| 1p8d | CO1 | Oxysterols receptor LXR-beta | / | 0.457 | |
| 1rfu | ADP | Pyridoxal kinase | 2.7.1.35 | 0.457 | |
| 1s3z | COA | Aminoglycoside N(6')-acetyltransferase type 1 | / | 0.457 | |
| 1tys | TMP | Thymidylate synthase | / | 0.457 | |
| 2cjm | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.457 | |
| 2q4b | NAP | Uncharacterized protein At5g02240 | / | 0.457 | |
| 3b70 | NAP | Enoyl reductase LovC | 1 | 0.457 | |
| 3c16 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.457 | |
| 3iel | U5P | Ribonuclease TTHA0252 | 3.1 | 0.457 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.457 | |
| 3qwb | NDP | Probable quinone oxidoreductase | 1.6.5.5 | 0.457 | |
| 3sgl | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.457 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.457 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.457 | |
| 4xzj | NAD | Putative NAD(+)--arginine ADP-ribosyltransferase Vis | 2.4.2.31 | 0.457 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.456 | |
| 1qcf | PP1 | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.456 | |
| 1qrp | HH0 | Pepsin A-4 | 3.4.23.1 | 0.456 | |
| 2d1c | NAP | Isocitrate dehydrogenase [NADP] | 1.1.1.42 | 0.456 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.456 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.456 | |
| 2pan | FAD | Glyoxylate carboligase | 4.1.1.47 | 0.456 | |
| 3akd | CDP | Cytidylate kinase | / | 0.456 | |
| 3biy | 01K | Histone acetyltransferase p300 | / | 0.456 | |
| 3cwq | ADP | ParA family chromosome partitioning protein | / | 0.456 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.456 | |
| 3hyo | ADP | Pyridoxal kinase | / | 0.456 | |
| 3p8z | 36A | Genome polyprotein | 2.1.1.56 | 0.456 | |
| 3p8z | SAH | Genome polyprotein | 2.1.1.56 | 0.456 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.456 | |
| 4fg8 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.456 | |
| 4obw | SAM | 2-methoxy-6-polyprenyl-1,4-benzoquinol methylase, mitochondrial | / | 0.456 | |
| 4wh3 | ATP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.456 | |
| 5dbf | NDP | Iridoid synthase | 1.3.1.99 | 0.456 | |
| 1fxs | NAP | GDP-L-fucose synthase | / | 0.455 | |
| 2jds | L20 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.455 | |
| 2oc2 | RX3 | Angiotensin-converting enzyme | 3.2.1 | 0.455 | |
| 2og8 | 1N8 | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.455 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.455 | |
| 2zu8 | GDD | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.455 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.455 | |
| 3gyu | DL7 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.455 | |
| 3nmp | PYV | Abscisic acid receptor PYL2 | / | 0.455 | |
| 3owa | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 3t7x | 4SH | Endothiapepsin | 3.4.23.22 | 0.455 | |
| 3vjc | ZGA | Squalene synthase | 2.5.1.21 | 0.455 | |
| 3vt5 | YI2 | Vitamin D3 receptor | / | 0.455 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 4bii | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.455 | |
| 4dk7 | 0KS | Oxysterols receptor LXR-beta | / | 0.455 | |
| 5dp2 | NAP | CurF | / | 0.455 | |
| 5kj6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.455 | |
| 1e1c | DCA | Methylmalonyl-CoA mutase large subunit | 5.4.99.2 | 0.454 | |
| 1g0n | NDP | Tetrahydroxynaphthalene reductase | 1.1.1.252 | 0.454 | |
| 1h6c | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.454 | |
| 1h6d | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.454 | |
| 1j1c | ADP | Glycogen synthase kinase-3 beta | 2.7.11.26 | 0.454 | |
| 1jnk | ANP | Mitogen-activated protein kinase 10 | 2.7.11.24 | 0.454 | |
| 1kvo | OAP | Phospholipase A2, membrane associated | / | 0.454 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1qbq | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.454 | |
| 1qbq | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.454 | |
| 1u0h | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.454 | |
| 1u8v | FAD | 4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase | / | 0.454 | |
| 1w5t | ANP | ORC1-type DNA replication protein 2 | / | 0.454 | |
| 2ag1 | TPP | Benzaldehyde lyase | / | 0.454 | |
| 2b9i | ADP | Mitogen-activated protein kinase FUS3 | 2.7.11.24 | 0.454 | |
| 2bi4 | NAD | Lactaldehyde reductase | 1.1.1.77 | 0.454 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.454 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.454 | |
| 2v6g | NAP | 3-oxo-Delta(4,5)-steroid 5-beta-reductase | / | 0.454 | |
| 3c9r | ATP | Thiamine-monophosphate kinase | / | 0.454 | |
| 3csc | ACO | Citrate synthase, mitochondrial | 2.3.3.1 | 0.454 | |
| 3mvj | XFE | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.454 | |
| 3pjt | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.454 | |
| 3pww | ROC | Endothiapepsin | 3.4.23.22 | 0.454 | |
| 3q8u | ADP | Nucleoside diphosphate kinase | / | 0.454 | |
| 3s7a | 684 | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3t3c | 017 | Gag-Pol polyprotein | 3.4.23.16 | 0.454 | |
| 3thr | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.454 | |
| 3v76 | FDA | Uncharacterized protein | / | 0.454 | |
| 4eo3 | FMN | Bacterioferritin comigratory protein/NADH dehydrogenase | / | 0.454 | |
| 4fd2 | ADP | Chaperone protein ClpB | / | 0.454 | |
| 4fg9 | ATP | Calcium/calmodulin-dependent protein kinase type 1 | 2.7.11.17 | 0.454 | |
| 4jld | ADP | Adenylate kinase | / | 0.454 | |
| 4mkh | AP5 | Adenylate kinase | / | 0.454 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.454 | |
| 5dju | FMN | NPH1-2 | / | 0.454 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.454 | |
| 5k2c | ZMA | Adenosine receptor A2a | / | 0.454 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.453 | |
| 1sgu | MK1 | Gag-Pol polyprotein | 3.4.23.16 | 0.453 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.453 | |
| 2bx8 | AZQ | Serum albumin | / | 0.453 | |
| 2c2a | ADP | Sensor histidine kinase | / | 0.453 | |
| 2fhn | BNI | Avidin-related protein 4/5 | / | 0.453 | |
| 2gbl | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.453 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.453 | |
| 2p2l | GDP | Ras-related C3 botulinum toxin substrate 1 | / | 0.453 | |
| 2xgs | 44P | Uncharacterized protein | / | 0.453 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.453 | |
| 3clb | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.453 | |
| 3e2s | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.453 | |
| 3gyt | DL4 | Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily | / | 0.453 | |
| 3q7d | NPX | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.453 | |
| 3s55 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.453 | |
| 3zy5 | GFB | GDP-fucose protein O-fucosyltransferase 1 | 2.4.1.221 | 0.453 | |
| 4e5k | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.453 | |
| 4i52 | 1HA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.453 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.453 | |
| 4pzs | ACO | Histone acetyltransferase p300 | / | 0.453 | |
| 5ej9 | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.453 | |
| 1eyy | NAP | NADP-dependent fatty aldehyde dehydrogenase | 1.2.1.4 | 0.452 | |
| 1j7u | ANP | Aminoglycoside 3'-phosphotransferase | 2.7.1.95 | 0.452 | |
| 1k74 | 544 | Peroxisome proliferator-activated receptor gamma | / | 0.452 | |
| 1nyt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.452 | |
| 1ppj | ANY | Cytochrome b | / | 0.452 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.452 | |
| 1xq6 | NAP | Uncharacterized protein At5g02240 | / | 0.452 | |
| 2eu8 | AP5 | Adenylate kinase | / | 0.452 | |
| 2f5z | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.452 | |
| 2x19 | GTP | GTP-binding nuclear protein GSP1/CNR1 | / | 0.452 | |
| 2ylz | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.452 | |
| 3cic | 316 | Beta-secretase 1 | 3.4.23.46 | 0.452 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.452 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4hl1 | ZZ7 | Metallo-beta-lactamase type 2 | / | 0.452 | |
| 4hle | 17V | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.452 | |
| 4jv6 | 18F | Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta | / | 0.452 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.452 | |
| 4y9q | C2E | Uncharacterized protein | / | 0.452 | |
| 4ytn | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.452 | |
| 5idw | NAP | Short-chain dehydrogenase/reductase SDR | / | 0.452 | |
| 1cs4 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.451 | |
| 1fdu | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1g6o | ADP | Cag alpha | / | 0.451 | |
| 1i5r | HYC | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.451 | |
| 1s7g | APR | NAD-dependent protein deacylase 2 | / | 0.451 | |
| 1tj0 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.451 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.451 | |
| 1z7e | UGA | Bifunctional polymyxin resistance protein ArnA | / | 0.451 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.451 | |
| 2dft | ADP | Shikimate kinase | 2.7.1.71 | 0.451 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2gd2 | CAA | Probable alpha-methylacyl-CoA racemase Mcr (2-methylacyl-CoA racemase) (2-arylpropionyl-CoA epimerase ) | / | 0.451 | |
| 2giv | ACO | Histone acetyltransferase KAT8 | / | 0.451 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.451 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.451 | |
| 2jla | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.451 | |
| 2oo7 | AP5 | Adenylate kinase | / | 0.451 | |
| 2psw | COA | N-alpha-acetyltransferase 50 | / | 0.451 | |
| 2r0p | K2C | Putative FAD-monooxygenase | / | 0.451 | |
| 2tdm | UMP | Thymidylate synthase | / | 0.451 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.451 | |
| 2yvg | NAD | Ferredoxin reductase | / | 0.451 | |
| 3hj9 | FMN | Uncharacterized protein | / | 0.451 | |
| 3iqi | ASN_GLU_ASN_ILE | Cysteine synthase | 2.5.1.47 | 0.451 | |
| 3qdl | FMN | Oxygen-insensitive NADPH nitroreductase | / | 0.451 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.451 | |
| 4bva | T3 | Ketimine reductase mu-crystallin | 1.5.1.25 | 0.451 | |
| 4cj4 | S3G | Integrase | / | 0.451 | |
| 4cr8 | NAD | N-acylmannosamine 1-dehydrogenase | 1.1.1.233 | 0.451 | |
| 4g67 | SAH | Uncharacterized ACR, COG1565 superfamily | / | 0.451 | |
| 4ge4 | 0KE | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.451 | |
| 4gyi | ADP | Uncharacterized protein | / | 0.451 | |
| 4hfm | NAP | 2-alkenal reductase (NADP(+)-dependent) | / | 0.451 | |
| 4ike | ADP | Adenylate kinase | / | 0.451 | |
| 4isk | 1JY | Thymidylate synthase | / | 0.451 | |
| 4mit | GTP | Rho-related protein racC | / | 0.451 | |
| 4u07 | ATP | Adenosine monophosphate-protein transferase FICD | 2.7.7.n1 | 0.451 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.451 | |
| 8dfr | NDP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4djh | JDC | Kappa-type opioid receptor | / | 0.451 | |
| 1edo | NAP | 3-oxoacyl-[acyl-carrier-protein] reductase 1, chloroplastic | 1.1.1.100 | 0.450 | |
| 1fy7 | COA | Histone acetyltransferase ESA1 | / | 0.450 | |
| 1l0o | ADP | Anti-sigma F factor | / | 0.450 | |
| 1r37 | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 0.450 | |
| 1u1i | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.450 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.450 | |
| 2c0c | NAP | Prostaglandin reductase 3 | 1 | 0.450 | |
| 2cdu | FAD | NADH oxidase | / | 0.450 | |
| 2ewm | NAD | (S)-1-Phenylethanol dehydrogenase | 1.1.1.311 | 0.450 | |
| 2ql6 | ADP | Nicotinamide riboside kinase 1 | / | 0.450 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3bbt | FMM | Receptor tyrosine-protein kinase erbB-4 | 2.7.10.1 | 0.450 | |
| 3ha7 | B32 | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.450 | |
| 3sdk | P3N | Proteasome subunit beta type-5 | 3.4.25.1 | 0.450 | |
| 3sdk | P3N | Proteasome subunit beta type-6 | 3.4.25.1 | 0.450 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.450 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.450 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.450 | |
| 4bf2 | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.450 | |
| 4bmv | NAP | Short-chain dehydrogenase | / | 0.450 | |
| 4fqs | LYA | Thymidylate synthase ThyA | / | 0.450 | |
| 4gyy | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.450 | |
| 4l4x | NDP | AmphI | / | 0.450 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.450 | |
| 5cfp | C2E | Stimulator of interferon genes protein | / | 0.450 | |
| 5jsc | FAD | Putative acyl-CoA dehydrogenase | / | 0.450 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 1nhk | CMP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.449 | |
| 1nq1 | 4HY | Thyroid hormone receptor beta | / | 0.449 | |
| 1p4m | ADP | Riboflavin kinase | 2.7.1.26 | 0.449 | |
| 1qmz | ATP | Cyclin-dependent kinase 2 | 2.7.11.22 | 0.449 | |
| 1s22 | ATP | Actin, alpha skeletal muscle | / | 0.449 | |
| 1tsv | UMP | Thymidylate synthase | / | 0.449 | |
| 1u7h | NAD | Putative ornithine cyclodeaminase | / | 0.449 | |
| 2bac | FAD | Putative aminooxidase | / | 0.449 | |
| 2bpw | 1IN | Gag-Pol polyprotein | 3.4.23.16 | 0.449 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.449 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.449 | |
| 2nua | COA | Succinate--CoA ligase [ADP-forming] subunit alpha | 6.2.1.5 | 0.449 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.449 | |
| 2yph | QQY | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.449 | |
| 3bts | NAD | Galactose/lactose metabolism regulatory protein GAL80 | / | 0.449 | |
| 3d8x | FAD | Thioredoxin reductase 1 | 1.8.1.9 | 0.449 | |
| 3dh8 | B4N | Uncharacterized protein PA1000 | / | 0.449 | |
| 3grr | SAH | Probable ribosomal RNA small subunit methyltransferase A | / | 0.449 | |
| 3idb | ANP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.449 | |
| 3kjs | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.449 | |
| 3kmc | 403 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.449 | |
| 3qd4 | 3Q6 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.449 | |
| 3qv1 | NAD | Glyceraldehyde-3-phosphate dehydrogenase GAPA1, chloroplastic | 1.2.1.13 | 0.449 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.449 | |
| 4hjf | C2E | GGDEF family protein | / | 0.449 | |
| 4ite | TEY | Vitamin D3 receptor | / | 0.449 | |
| 4j7x | NAP | Sepiapterin reductase | 1.1.1.153 | 0.449 | |
| 4kiq | 1RA | Mitogen-activated protein kinase 14 | / | 0.449 | |
| 4rph | GDU | UDP-galactopyranose mutase | 5.4.99.9 | 0.449 | |
| 4u03 | GTP | Cyclic GMP-AMP synthase | / | 0.449 | |
| 4xgu | ADP | Putative pachytene checkpoint protein 2 | / | 0.449 | |
| 4yai | NAI | C alpha-dehydrogenase | / | 0.449 | |
| 4z44 | FAD | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.449 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.449 | |
| 5kjc | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.449 | |
| 1bdb | NAD | Cis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase | / | 0.448 | |
| 1egd | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.448 | |
| 1eji | THF | Serine hydroxymethyltransferase, cytosolic | / | 0.448 | |
| 1im2 | ADP | ATP-dependent protease ATPase subunit HslU | / | 0.448 | |
| 1j3j | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 1kph | SAH | Cyclopropane mycolic acid synthase 1 | 2.1.1.79 | 0.448 | |
| 1lwl | DSO | Camphor 5-monooxygenase | 1.14.15.1 | 0.448 | |
| 1opb | RET | Retinol-binding protein 2 | / | 0.448 | |
| 1xg5 | NAP | Dehydrogenase/reductase SDR family member 11 | / | 0.448 | |
| 1zpt | FAD | 5,10-methylenetetrahydrofolate reductase | 1.5.1.20 | 0.448 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.448 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.448 | |
| 2gej | GDD | Phosphatidyl-myo-inositol mannosyltransferase | 2.4.1.57 | 0.448 | |
| 2hcd | BIV | Vitamin D3 receptor A | / | 0.448 | |
| 2hfp | NSI | Peroxisome proliferator-activated receptor gamma | / | 0.448 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.448 | |
| 2zd1 | T27 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 3d3w | NAP | L-xylulose reductase | 1.1.1.10 | 0.448 | |
| 3daw | ATP | Actin, alpha skeletal muscle | / | 0.448 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.448 | |
| 3ruv | ANP | Chaperonin | / | 0.448 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.448 | |
| 3x2f | NAI | Adenosylhomocysteinase | / | 0.448 | |
| 4bgi | I4I | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.448 | |
| 4g73 | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.448 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.448 | |
| 4k88 | HFG | Bifunctional glutamate/proline--tRNA ligase | 6.1.1.15 | 0.448 | |
| 1e82 | M90 | Endothiapepsin | 3.4.23.22 | 0.447 | |
| 1gwn | GTP | Rho-related GTP-binding protein RhoE | / | 0.447 | |
| 1j3k | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.447 | |
| 1nbi | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.447 | |
| 1o8c | NDP | Probable acrylyl-CoA reductase AcuI | 1.3.1.84 | 0.447 | |
| 1osv | CHC | Bile acid receptor | / | 0.447 | |
| 1q51 | CAA | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.447 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.447 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.447 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.447 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.447 | |
| 2b4r | AES | Glyceraldehyde-3-phosphate dehydrogenase | / | 0.447 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.447 | |
| 2ieb | ZID | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.447 | |
| 2vzz | SCA | Putative succinyl-CoA transferase Rv0802c | 2.8.3 | 0.447 | |
| 2zdy | ADP | [Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 4, mitochondrial | 2.7.11.2 | 0.447 | |
| 3c14 | GSP | Guanine nucleotide-binding protein G(s) subunit alpha isoforms short | / | 0.447 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.447 | |
| 3g7j | GTX | Glutathione transferase GST1-4 | / | 0.447 | |
| 3hwx | TPP | 2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase | / | 0.447 | |
| 3mte | SAM | 16S rRNA (adenine(1408)-N(1))-methyltransferase | 2.1.1.180 | 0.447 | |
| 3otq | MZL | Bifunctional epoxide hydrolase 2 | 3.3.2.10 | 0.447 | |
| 3r6c | 17N | Anthranilate phosphoribosyltransferase | / | 0.447 | |
| 3stx | BKA | Methylketone synthase I | / | 0.447 | |
| 3tfn | 2CJ | Dehydrosqualene synthase | / | 0.447 | |
| 3vfa | 031 | Gag-Pol polyprotein | 3.4.23.16 | 0.447 | |
| 3wqm | B29 | Diterpene synthase | 3.1.7.8 | 0.447 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.447 | |
| 3zbz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.447 | |
| 4h1v | GNP | Dynamin-1-like protein | 3.6.5.5 | 0.447 | |
| 4mq1 | 2C3 | Dual specificity tyrosine-phosphorylation-regulated kinase 1A | 2.7.12.1 | 0.447 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.447 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.447 | |
| 4xxv | NAD | 3-isopropylmalate dehydrogenase | / | 0.447 | |
| 1eii | RTL | Retinol-binding protein 2 | / | 0.446 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.446 | |
| 1kor | ANP | Argininosuccinate synthase | / | 0.446 | |
| 1lbc | CYZ | Glutamate receptor 2 | / | 0.446 | |
| 1lon | IMO | Adenylosuccinate synthetase isozyme 1 | / | 0.446 | |
| 1mp0 | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.446 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.446 | |
| 2c9c | ATP | Psp operon transcriptional activator | / | 0.446 | |
| 2clq | STU | Mitogen-activated protein kinase kinase kinase 5 | 2.7.11.25 | 0.446 | |
| 2e93 | B29 | Geranylgeranyl pyrophosphate synthase | / | 0.446 | |
| 2g78 | REA | Cellular retinoic acid-binding protein 2 | / | 0.446 | |
| 2q2v | NAD | Beta-D-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.446 | |
| 2rhq | GAX | Phenylalanine--tRNA ligase alpha subunit | / | 0.446 | |
| 2uyw | BTN | Avd protein | / | 0.446 | |
| 2vkv | TDC | Tetracycline repressor protein class D | / | 0.446 | |
| 2x9d | ITC | Tetracycline repressor protein class D | / | 0.446 | |
| 2yyy | NAP | Glyceraldehyde-3-phosphate dehydrogenase | 1.2.1.59 | 0.446 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.446 | |
| 3i5z | Z48 | Mitogen-activated protein kinase 1 | 2.7.11.24 | 0.446 | |
| 3iej | 599 | Cathepsin S | 3.4.22.27 | 0.446 | |
| 3lnm | NAP | Voltage-gated potassium channel subunit beta-2 | / | 0.446 | |
| 3nf4 | FAD | Acyl-CoA dehydrogenase domain-containing protein | / | 0.446 | |
| 3oe1 | TDL | Pyruvate decarboxylase | 4.1.1.1 | 0.446 | |
| 3qcx | 3Q2 | 3-phosphoinositide-dependent protein kinase 1 | 2.7.11.1 | 0.446 | |
| 3tnl | NAD | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3vwd | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.446 | |
| 4az3 | S35 | Lysosomal protective protein | 3.4.16.5 | 0.446 | |
| 4bl5 | GFB | GDP-L-fucose synthase | 1.1.1.271 | 0.446 | |
| 4nau | AGS | Phosphopantetheine adenylyltransferase | / | 0.446 | |
| 4qzu | RTL | Retinol-binding protein 2 | / | 0.446 | |
| 4r21 | STR | Cytochrome P450 family 17 polypeptide 2 | / | 0.446 | |
| 4y3z | F41 | Endothiapepsin | 3.4.23.22 | 0.446 | |
| 4zla | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.446 | |
| 5c3j | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.446 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 5hwq | CAA | Hydroxymethylglutaryl-CoA synthase | / | 0.446 | |
| 1c7o | PPG | Hemolysin | / | 0.445 | |
| 1dgm | ADN | Adenosine kinase | 2.7.1.20 | 0.445 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.445 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.445 | |
| 1gee | NAD | Glucose 1-dehydrogenase | 1.1.1.47 | 0.445 | |
| 1gjv | AGS | [3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial | 2.7.11.4 | 0.445 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.445 | |
| 1sby | NAD | Alcohol dehydrogenase | 1.1.1.1 | 0.445 | |
| 1svl | ADP | Large T antigen | 3.6.4 | 0.445 | |
| 1t7j | 478 | Gag-Pol polyprotein | 3.4.23.16 | 0.445 | |
| 1uop | GLY_PHE_GLU_PRO | Prolyl endopeptidase | 3.4.21.26 | 0.445 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.445 | |
| 2cns | ACO | Ribosomal-protein-alanine acetyltransferase | / | 0.445 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.445 | |
| 2hc4 | VDX | Vitamin D3 receptor A | / | 0.445 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.445 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.445 | |
| 2z9d | FMN | FMN-dependent NADH-azoreductase | / | 0.445 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3bgx | TMP | Thymidylate synthase | / | 0.445 | |
| 3bxz | ADP | Protein translocase subunit SecA | / | 0.445 | |
| 3cid | 318 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.445 | |
| 3qfr | FAD | NADPH--cytochrome P450 reductase | / | 0.445 | |
| 3rus | ADP | Chaperonin | / | 0.445 | |
| 3uoy | NAP | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.445 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.445 | |
| 3uzw | NAP | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.445 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.445 | |
| 4a4q | UX9 | Pol protein | / | 0.445 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 4dpw | AGS | Mevalonate diphosphate decarboxylase | / | 0.445 | |
| 4gtp | 7TP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.445 | |
| 4jnc | 1LF | Bifunctional epoxide hydrolase 2 | 3.1.3.76 | 0.445 | |
| 4k6m | SAH | Genome polyprotein | / | 0.445 | |
| 4lxh | C1E | Alpha/beta hydrolase fold | / | 0.445 | |
| 4oug | LP5 | Peptidoglycan recognition protein 1 | / | 0.445 | |
| 4qny | ANP | Mitogen activated protein kinase, putative | / | 0.445 | |
| 4rhe | FMN | Flavin prenyltransferase UbiX | / | 0.445 | |
| 5a3b | APR | SIR2 family protein | / | 0.445 | |
| 5jqb | IBP | Envelope glycoprotein | / | 0.445 | |
| 1bxo | PP7 | Penicillopepsin-1 | 3.4.23.20 | 0.444 | |
| 1ek2 | CDU | Bifunctional epoxide hydrolase 2 | / | 0.444 | |
| 1gqy | ACP | UDP-N-acetylmuramate--L-alanine ligase | 6.3.2.8 | 0.444 | |
| 1h6b | NDP | Glucose--fructose oxidoreductase | 1.1.99.28 | 0.444 | |
| 1mj9 | COA | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1mjb | ACO | Histone acetyltransferase ESA1 | / | 0.444 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.444 | |
| 1nlv | ATP | Major actin | / | 0.444 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1ydt | IQB | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.444 | |
| 1yt0 | ADP | Endoplasmin | / | 0.444 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.444 | |
| 2gmj | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.444 | |
| 2gn8 | NAP | UDP-N-acetylglucosamine 4,6-dehydratase (inverting) | 4.2.1.115 | 0.444 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.444 | |
| 2qfx | NDP | Isocitrate dehydrogenase [NADP], mitochondrial | 1.1.1.42 | 0.444 | |
| 2r4u | ADP | Glycogen synthase | 2.4.1.21 | 0.444 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 2w2l | NAD | D-mandelate dehydrogenase | / | 0.444 | |
| 2xlr | FAD | Putative flavin-containing monooxygenase | / | 0.444 | |
| 2zu9 | GDP | Mannosyl-3-phosphoglycerate synthase | 2.4.1.217 | 0.444 | |
| 3abx | RCB | Glucanase | / | 0.444 | |
| 3f63 | GTX | Glutathione transferase GST1-4 | / | 0.444 | |
| 3kjr | NAP | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.444 | |
| 3oq6 | PFB | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.444 | |
| 3pju | C2E | Diguanylate cyclase/phosphodiesterase | / | 0.444 | |
| 3q9t | FAY | Uncharacterized protein | / | 0.444 | |
| 3sgt | P09 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | / | 0.444 | |
| 3t7p | 7SP | Endothiapepsin | 3.4.23.22 | 0.444 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.444 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.444 | |
| 4i4z | 2NE | 1,4-dihydroxy-2-naphthoyl-CoA synthase | / | 0.444 | |
| 4n48 | SAM | Cap-specific mRNA (nucleoside-2'-O-)-methyltransferase 1 | 2.1.1.57 | 0.444 | |
| 4rd2 | GNP | Translation initiation factor 2 subunit gamma | / | 0.444 | |
| 4wlo | NAI | Malate dehydrogenase, mitochondrial | 1.1.1.37 | 0.444 | |
| 4xcj | ADP | Heat shock cognate 90 kDa protein | / | 0.444 | |
| 1i2b | NAD | UDP-sulfoquinovose synthase, chloroplastic | 3.13.1.1 | 0.443 | |
| 1i44 | ACP | Insulin receptor | 2.7.10.1 | 0.443 | |
| 1jqd | SAH | Histamine N-methyltransferase | 2.1.1.8 | 0.443 | |
| 1n08 | ADP | Riboflavin kinase | 2.7.1.26 | 0.443 | |
| 1og6 | NAP | Oxidoreductase YdhF | 1 | 0.443 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.443 | |
| 1t90 | NAD | Malonate-semialdehyde dehydrogenase | 1.2.1.27 | 0.443 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.443 | |
| 1uuo | BRF | Dihydroorotate dehydrogenase (quinone), mitochondrial | 1.3.5.2 | 0.443 | |
| 1vkg | CRI | Histone deacetylase 8 | 3.5.1.98 | 0.443 | |
| 1xkd | NAP | Isocitrate dehydrogenase [NADP] | / | 0.443 | |
| 1ykf | NAP | NADP-dependent isopropanol dehydrogenase | 1.1.1.80 | 0.443 | |
| 2a1t | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.443 | |
| 2ham | C33 | Vitamin D3 receptor | / | 0.443 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.443 | |
| 2jn3 | JN3 | Fatty acid-binding protein, liver | / | 0.443 | |
| 2p83 | MR0 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2pnj | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.443 | |
| 2r9v | ATP | ATP synthase subunit alpha | / | 0.443 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.443 | |
| 2yp0 | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 3b8z | 294 | A disintegrin and metalloproteinase with thrombospondin motifs 5 | 3.4.24 | 0.443 | |
| 3e8n | VRA | Dual specificity mitogen-activated protein kinase kinase 1 | 2.7.12.2 | 0.443 | |
| 3pls | ANP | Macrophage-stimulating protein receptor | 2.7.10.1 | 0.443 | |
| 3q0u | LL3 | HTH-type transcriptional regulator EthR | / | 0.443 | |
| 3qvs | NAD | Myo-inositol-1-phosphate synthase (Ino1) | / | 0.443 | |
| 3tdv | GDP | Gentamicin resistance protein | / | 0.443 | |
| 3w8f | NAD | 3-hydroxybutyrate dehydrogenase | / | 0.443 | |
| 4aa0 | AA0 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 4b72 | 2FB | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4b8u | IBK | 3-hydroxydecanoyl-[acyl-carrier-protein] dehydratase | 4.2.1.59 | 0.443 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 4c2j | COA | 3-ketoacyl-CoA thiolase, mitochondrial | 2.3.1.16 | 0.443 | |
| 4do3 | 0LA | Fatty-acid amide hydrolase 1 | 3.5.1.99 | 0.443 | |
| 4e1b | TXA | Threonylcarbamoyl-AMP synthase | 2.7.7.87 | 0.443 | |
| 4ekk | ANP | RAC-alpha serine/threonine-protein kinase | 2.7.11.1 | 0.443 | |
| 4fc7 | NAP | Peroxisomal 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.443 | |
| 4hbm | 0Y7 | E3 ubiquitin-protein ligase Mdm2 | 6.3.2 | 0.443 | |
| 4j7u | NAP | Sepiapterin reductase | 1.1.1.153 | 0.443 | |
| 4jlo | ADP | Adenylate kinase | / | 0.443 | |
| 4n9i | PCG | Catabolite expression activator | / | 0.443 | |
| 4nec | SAH | Putative SAM-dependent methyltransferase | / | 0.443 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.442 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.442 | |
| 1cq7 | PY5 | Aspartate aminotransferase | 2.6.1.1 | 0.442 | |
| 1g5q | ASP_SER_TYR_THR_CYS | Epidermin decarboxylase | 4.1.1 | 0.442 | |
| 1i7g | AZ2 | Peroxisome proliferator-activated receptor alpha | / | 0.442 | |
| 1n3r | GTP | GTP cyclohydrolase 1 | 3.5.4.16 | 0.442 | |
| 1tj2 | FAD | Bifunctional protein PutA | 1.5.5.2 | 0.442 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.442 | |
| 1zdw | FLV | Prenyltransferase | / | 0.442 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 2d0o | ADP | Diol dehydratase-reactivating factor alpha subunit | / | 0.442 | |
| 2d4v | NAD | Isocitrate dehydrogenase [NADP] | / | 0.442 | |
| 2e20 | B4P | Propionate kinase | / | 0.442 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.442 | |
| 2f1k | NAP | Prephenate dehydrogenase | / | 0.442 | |
| 2fhk | MFN | Formylmethanofuran--tetrahydromethanopterin formyltransferase | 2.3.1.101 | 0.442 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.442 | |
| 2jkv | NAP | 6-phosphogluconate dehydrogenase, decarboxylating | 1.1.1.44 | 0.442 | |
| 2pkr | NDP | Glyceraldehyde-3-phosphate dehydrogenase A, chloroplastic | 1.2.1.13 | 0.442 | |
| 2rm2 | W43 | Genome polyprotein | / | 0.442 | |
| 2wdq | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.442 | |
| 2wdq | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.442 | |
| 2x3j | ATP | AcsD | / | 0.442 | |
| 2ya3 | J7V | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.442 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3b92 | 440 | Disintegrin and metalloproteinase domain-containing protein 17 | 3.4.24.86 | 0.442 | |
| 3dga | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.442 | |
| 3gw9 | VNI | Lanosterol 14-alpha-demethylase | / | 0.442 | |
| 3i59 | N6R | CRP-like cAMP-activated global transcriptional regulator | / | 0.442 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.442 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.442 | |
| 3mb7 | 14I | Casein kinase II subunit alpha | 2.7.11.1 | 0.442 | |
| 3mkh | FAD | Nitroalkane oxidase | / | 0.442 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.442 | |
| 3rpe | FAD | Putative modulator of drug activity | / | 0.442 | |
| 3u9e | COA | Lmo1369 protein | / | 0.442 | |
| 3vrb | FTN | Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial | / | 0.442 | |
| 3vrb | FTN | Cytochrome b-large subunit | / | 0.442 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.442 | |
| 4dti | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.442 | |
| 4elb | 34R | Dihydrofolate reductase | / | 0.442 | |
| 4gbe | SAH | DNA adenine methylase | 2.1.1.72 | 0.442 | |
| 4hwk | NAP | Sepiapterin reductase | 1.1.1.153 | 0.442 | |
| 4jzy | FAD | Cryptochrome-1 | / | 0.442 | |
| 4kov | KOV | Uncharacterized protein | / | 0.442 | |
| 4lnb | ED5 | CaaX farnesyltransferase beta subunit Ram1 | / | 0.442 | |
| 4qi5 | FAD | Cellobiose dehydrogenase | / | 0.442 | |
| 5emh | NAP | Iridoid synthase | 1.3.1.99 | 0.442 | |
| 1avd | BTN | Avidin | / | 0.441 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.441 | |
| 1gvt | 2ZS | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 1ie9 | VDX | Vitamin D3 receptor | / | 0.441 | |
| 1iy8 | NAD | Levodione reductase | / | 0.441 | |
| 1j39 | UPG | DNA beta-glucosyltransferase | / | 0.441 | |
| 1mzs | 669 | 3-oxoacyl-[acyl-carrier-protein] synthase 3 | / | 0.441 | |
| 1npv | L27 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 1odc | A8B | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 1w78 | PD8 | Dihydrofolate synthase/folylpolyglutamate synthase | 6.3.2.12 | 0.441 | |
| 2gcq | DOI | Adenylosuccinate synthetase | / | 0.441 | |
| 2ibt | NEA | Modification methylase TaqI | 2.1.1.72 | 0.441 | |
| 2jji | 0QS | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 2oiq | STI | Proto-oncogene tyrosine-protein kinase Src | 2.7.10.2 | 0.441 | |
| 2okc | SAM | Probable type I restriction enzyme BthVORF4518P M protein | 2.1.1.72 | 0.441 | |
| 2ozu | ACO | Histone acetyltransferase KAT6A | / | 0.441 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.441 | |
| 2r0g | 7CK | Putative FAD-monooxygenase | / | 0.441 | |
| 2wu5 | CBE | Succinate dehydrogenase iron-sulfur subunit | 1.3.5.1 | 0.441 | |
| 2wu5 | CBE | Succinate dehydrogenase cytochrome b556 subunit | / | 0.441 | |
| 2x86 | ADP | ADP-L-glycero-D-manno-heptose-6-epimerase | / | 0.441 | |
| 2xls | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2xvf | FAD | Putative flavin-containing monooxygenase | / | 0.441 | |
| 2yyl | FAD | 4-hydroxyphenylacetate 3-monooxygenase oxygenase component | 1.14.14.9 | 0.441 | |
| 2znp | K55 | Peroxisome proliferator-activated receptor delta | / | 0.441 | |
| 2zyn | BCD | Periplasmic binding protein | / | 0.441 | |
| 3dk1 | G05 | Gag-Pol polyprotein | 3.4.23.16 | 0.441 | |
| 3h8g | BES | Cytosol aminopeptidase | 3.4.11.1 | 0.441 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.441 | |
| 3inv | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 3kr4 | BES | M17 leucyl aminopeptidase | / | 0.441 | |
| 3l0h | GTX | Glutathione S-transferase A1 | 2.5.1.18 | 0.441 | |
| 3pmy | 41L | Endothiapepsin | 3.4.23.22 | 0.441 | |
| 3ule | ATP | Actin-related protein 2 | / | 0.441 | |
| 3wag | TYD | Glycosyltransferase | / | 0.441 | |
| 3zsh | 469 | Mitogen-activated protein kinase 14 | / | 0.441 | |
| 4an4 | DUD | Putative glycosyl transferase | / | 0.441 | |
| 4bb5 | HD2 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.441 | |
| 4d5g | FAD | Cyclohexane-1,2-dione hydrolase | 3.7.1.11 | 0.441 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.441 | |
| 4fcw | ADP | Chaperone protein ClpB | / | 0.441 | |
| 4o1b | DGB | Nicotinamide phosphoribosyltransferase | 2.4.2.12 | 0.441 | |
| 4pzr | COA | Histone acetyltransferase p300 | / | 0.441 | |
| 4rkf | GNP | Ras-related protein Rab-3 | / | 0.441 | |
| 4rr6 | A3S | Probable threonine--tRNA ligase 2 | 6.1.1.3 | 0.441 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.441 | |
| 4yxm | 2BA | DNA integrity scanning protein DisA | / | 0.441 | |
| 5dcy | NAP | Iridoid synthase | 1.3.1.99 | 0.441 | |
| 5fkn | TDC | Tetracycline repressor protein class D | / | 0.441 | |
| 5fm7 | ADP | RuvB-like helicase | / | 0.441 | |
| 5kl9 | COA | Acyl-CoA thioester hydrolase YbgC | 3.1.2 | 0.441 | |
| 1al8 | DHP | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.440 | |
| 1efv | FAD | Electron transfer flavoprotein subunit alpha, mitochondrial | / | 0.440 | |
| 1kap | GLY_SER_ASN_SER | Serralysin | 3.4.24.40 | 0.440 | |
| 1ksz | PGS | Adenylosuccinate synthetase | / | 0.440 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 alpha chain | / | 0.440 | |
| 1kzu | RG1 | Light-harvesting protein B-800/850 beta chain | / | 0.440 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.440 | |
| 1sx4 | ADP | 60 kDa chaperonin | / | 0.440 | |
| 1t9g | FAD | Medium-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.7 | 0.440 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.440 | |
| 2ako | ADP | Glutamate 5-kinase | / | 0.440 | |
| 2ard | FDA | Flavin-dependent tryptophan halogenase PrnA | 1.14.19.9 | 0.440 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.440 | |
| 2cmv | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 2eer | NAD | NAD-dependent alcohol dehydrogenase | 1.1.1.1 | 0.440 | |
| 2g5c | NAD | Prephenate dehydrogenase | / | 0.440 | |
| 2har | OCC | Vitamin D3 receptor | / | 0.440 | |
| 2hyd | ADP | Putative multidrug export ATP-binding/permease protein SAV1866 | 3.6.3 | 0.440 | |
| 2j14 | GNI | Peroxisome proliferator-activated receptor delta | / | 0.440 | |
| 2ok8 | FAD | Ferredoxin--NADP reductase, apicoplast | / | 0.440 | |
| 2rgo | FAD | Alpha-Glycerophosphate Oxidase | / | 0.440 | |
| 2trt | TAC | Tetracycline repressor protein class D | / | 0.440 | |
| 2y4g | TIR | TamL | / | 0.440 | |
| 2zjm | F1M | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 3ad9 | NAD | Subunit alpha of sarocosine oxidase | / | 0.440 | |
| 3aw9 | NAD | NAD-dependent epimerase/dehydratase | / | 0.440 | |
| 3cx4 | ADP | Glycogen synthase | 2.4.1.21 | 0.440 | |
| 3eku | CY9 | Actin-5C | / | 0.440 | |
| 3kds | NHX | ATP-dependent zinc metalloprotease FtsH | / | 0.440 | |
| 3kq7 | KQ7 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3m6g | ATP | Actin, alpha skeletal muscle | / | 0.440 | |
| 3rf7 | NAD | Iron-containing alcohol dehydrogenase | / | 0.440 | |
| 3vs5 | VSG | Tyrosine-protein kinase HCK | 2.7.10.2 | 0.440 | |
| 3w0a | DS5 | Vitamin D3 receptor | / | 0.440 | |
| 3wcz | NAP | Aldo-keto reductase AKR2E4 | / | 0.440 | |
| 3wix | LC3 | Induced myeloid leukemia cell differentiation protein Mcl-1 | / | 0.440 | |
| 4dwv | NAJ | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.440 | |
| 4e5n | NAD | Phosphonate dehydrogenase | 1.20.1.1 | 0.440 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.440 | |
| 4h5c | YS4 | Farnesyl pyrophosphate synthase | 2.5.1.10 | 0.440 | |
| 4i2p | G73 | Gag-Pol polyprotein | 2.7.7.49 | 0.440 | |
| 4iar | ERM | 5-hydroxytryptamine receptor 1B | / | 0.440 | |
| 4j5r | A1R | O-acetyl-ADP-ribose deacetylase 1 | 3.5.1 | 0.440 | |
| 4kc4 | WS3 | Histo-blood group ABO system transferase | / | 0.440 | |
| 4l03 | NAP | Isocitrate dehydrogenase [NADP] cytoplasmic | 1.1.1.42 | 0.440 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.440 | |
| 4o8a | FAD | Bifunctional protein PutA | 1.2.1.88 | 0.440 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.440 | |
| 4qg1 | DTP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.440 | |
| 4wji | NAP | Putative cyclohexadienyl dehydrogenase and ADH prephenate dehydrogenase | / | 0.440 | |
| 5byl | GCP | Bifunctional AAC/APH | 2.3.1 | 0.440 | |
| 5eoy | ADP | Type 4 fimbrial biogenesis protein PilM | / | 0.440 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.440 |