scPDB - Distribution of Binding site Similarity values of 4hxs entry / Site 1

PDB ID	HET	Uniprot Name	EC Number
4hxs	1A3	Bromodomain-containing protein 4

Complex with similar binding sites

PDB ID	HET	Uniprot Name	EC Number	Binding Site Similarity
4hxs	1A3	Bromodomain-containing protein 4	/	1.000
4hxn	1A7	Bromodomain-containing protein 4	/	0.797
4hxr	1A4	Bromodomain-containing protein 4	/	0.667
4c67	L5S	Bromodomain-containing protein 4	/	0.647
4lrg	1XB	Bromodomain-containing protein 4	/	0.639
4hby	13F	Bromodomain-containing protein 4	/	0.637
4bw3	9BM	Bromodomain-containing protein 4	/	0.633
4o70	1QK	Bromodomain-containing protein 4	/	0.630
4lr6	1XA	Bromodomain-containing protein 4	/	0.621
4j0s	1H3	Bromodomain-containing protein 4	/	0.619
4o76	1M3	Bromodomain-containing protein 4	/	0.619
4nqm	Y1Z	Bromodomain-containing protein 4	/	0.615
2yel	WSH	Bromodomain-containing protein 4	/	0.614
4bjx	73B	Bromodomain-containing protein 4	/	0.613
4men	25K	Bromodomain-containing protein 4	/	0.612
4a9o	A9O	Bromodomain-containing protein 2	/	0.610
4c66	H4C	Bromodomain-containing protein 4	/	0.609
4uyf	73B	Bromodomain-containing protein 2	/	0.607
4ogi	R78	Bromodomain-containing protein 4	/	0.602
4a9l	P9L	Bromodomain-containing protein 4	/	0.599
4qzs	JQ1	Bromodomain-containing protein 4	/	0.599
4j0r	1H2	Bromodomain-containing protein 4	/	0.596
4mr4	1K0	Bromodomain-containing protein 4	/	0.596
2ydw	WSH	Bromodomain-containing protein 2	/	0.593
4bw1	S5B	Bromodomain-containing protein 4	/	0.591
4bw2	UTH	Bromodomain-containing protein 4	/	0.587
3aqa	BYH	Bromodomain-containing protein 2	/	0.586
4a9n	A9N	Bromodomain-containing protein 2	/	0.586
4mep	24Y	Bromodomain-containing protein 4	/	0.586
4o74	R78	Bromodomain-containing protein 4	/	0.582
4uyg	73B	Bromodomain-containing protein 2	/	0.582
4akn	S5B	Bromodomain-containing protein 2	/	0.581
3zyu	1GH	Bromodomain-containing protein 4	/	0.578
4alh	A9P	Bromodomain-containing protein 2	/	0.578
4lyw	21Q	Bromodomain-containing protein 4	/	0.577
4meq	25O	Bromodomain-containing protein 4	/	0.577
4flp	JQ1	Bromodomain testis-specific protein	/	0.575
4hxo	1A6	Bromodomain-containing protein 4	/	0.573
4o71	CPB	Bromodomain-containing protein 4	/	0.567
4j3i	1K0	Bromodomain-containing protein 4	/	0.564
4hbw	14Z	Bromodomain-containing protein 4	/	0.555
4mr6	1K0	Bromodomain-containing protein 2	/	0.555
2yem	WSH	Bromodomain-containing protein 4	/	0.554
4f3i	0S6	Bromodomain-containing protein 4	/	0.554
4a9i	P9I	Bromodomain-containing protein 2	/	0.548
4bw4	9B6	Bromodomain-containing protein 4	/	0.548
4j1p	1K0	Bromodomain-containing protein 2	/	0.548
4cfl	8DQ	Bromodomain-containing protein 4	/	0.545
4o78	SAV	Bromodomain-containing protein 4	/	0.545
4a9e	3PF	Bromodomain-containing protein 2	/	0.543
2yek	EAM	Bromodomain-containing protein 2	/	0.542
4alg	1GH	Bromodomain-containing protein 2	/	0.539
4nr5	2LL	CREB-binding protein	/	0.539
4py6	R78	Bromodomain protein, putative	/	0.531
4cfk	LY2	Bromodomain-containing protein 4	/	0.530
4gpj	0Q1	Bromodomain-containing protein 4	/	0.524
5bt4	2LO	Bromodomain-containing protein 4	/	0.523
5bt5	2LO	Bromodomain-containing protein 2	/	0.523
4meo	25V	Bromodomain-containing protein 4	/	0.522
4hxm	1A8	Bromodomain-containing protein 4	/	0.514
4ryv	ZEA	Protein LlR18A	/	0.503
4mr5	1K0	Bromodomain-containing protein 2	/	0.499
3svg	ODR	Bromodomain-containing protein 4	/	0.497
3ue4	DB8	Tyrosine-protein kinase ABL1	2.7.10.2	0.497
1rx8	FOL	Dihydrofolate reductase	1.5.1.3	0.496
3pqb	VGP	Putative oxidoreductase	/	0.493
4ap3	FAD	Steroid monooxygenase	/	0.490
4fhi	0S4	Vitamin D3 receptor A	/	0.488
4jib	1L6	cGMP-dependent 3',5'-cyclic phosphodiesterase	3.1.4.17	0.487
1h66	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.483
2iod	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.483
2po7	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.483
4nr8	2LL	Bromodomain-containing protein 4	/	0.483
4wa9	AXI	Tyrosine-protein kinase ABL1	2.7.10.2	0.483
1r2j	FAD	FkbI	/	0.482
4elb	34R	Dihydrofolate reductase	/	0.482
2pui	ADP	Methylthioribose kinase	2.7.1.100	0.481
4bzn	UGX	Serine/threonine-protein kinase pim-1	2.7.11.1	0.481
2cf6	NAP	Cinnamyl alcohol dehydrogenase 5	1.1.1.195	0.480
2hcd	BIV	Vitamin D3 receptor A	/	0.480
2i4j	DRJ	Peroxisome proliferator-activated receptor gamma	/	0.480
1vj3	TAB	Dihydrofolate reductase	1.5.1.3	0.479
2ovh	AS0	Progesterone receptor	/	0.479
3nr4	PYV	Abscisic acid receptor PYL2	/	0.479
3vt8	YI3	Vitamin D3 receptor	/	0.479
4a8v	2AN	Major pollen allergen Bet v 1-J	/	0.479
3zux	TCH	Transporter	/	0.478
4ir5	IR5	Bromodomain adjacent to zinc finger domain protein 2B	/	0.478
4nyv	15E	CREB-binding protein	/	0.478
2w9s	TOP	Dihydrofolate reductase type 1 from Tn4003	1.5.1.3	0.477
3mdv	CL6	Cholesterol 24-hydroxylase	/	0.477
3srq	Q19	Dihydrofolate reductase	1.5.1.3	0.477
4nmb	FAD	Bifunctional protein PutA	/	0.477
5hs1	VOR	Lanosterol 14-alpha demethylase	/	0.477
4bf2	STU	Mitogen-activated protein kinase kinase kinase 5	2.7.11.25	0.476
4feq	0T8	Tyrosine-protein kinase receptor TYRO3	2.7.10.1	0.476
3d84	NDP	Dihydrofolate reductase	1.5.1.3	0.475
3nrr	D16	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.475
4a83	DXC	Major pollen allergen Bet v 1-A	/	0.475
1uy6	PU3	Heat shock protein HSP 90-alpha	/	0.474
3ctj	320	Hepatocyte growth factor receptor	2.7.10.1	0.474
4dgn	LU2	Casein kinase II subunit alpha	2.7.11.1	0.474
5csh	ATP	Casein kinase II subunit alpha	2.7.11.1	0.474
2vz6	FEF	Calcium/calmodulin-dependent protein kinase type II subunit alpha	2.7.11.17	0.473
3kjs	DQ1	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.473
3myk	ANP	Myosin-2 heavy chain	/	0.473
3vt7	VDX	Vitamin D3 receptor	/	0.473
4dp3	MMV	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.473
4erf	0R3	E3 ubiquitin-protein ligase Mdm2	6.3.2	0.473
1dr3	HBI	Dihydrofolate reductase	1.5.1.3	0.472
1ia3	TQ5	Dihydrofolate reductase	1.5.1.3	0.472
1ia4	TQ6	Dihydrofolate reductase	1.5.1.3	0.472
2i4p	DRH	Peroxisome proliferator-activated receptor gamma	/	0.472
2xls	FAD	Putative flavin-containing monooxygenase	/	0.472
3mqe	416	Prostaglandin G/H synthase 2	1.14.99.1	0.472
1cqp	803	Integrin alpha-L	/	0.471
1tvr	TB9	Gag-Pol polyprotein	2.7.7.49	0.471
2j9g	ANP	Biotin carboxylase	6.3.4.14	0.471
2w9h	TOP	Dihydrofolate reductase	1.5.1.3	0.471
3gw9	VNI	Lanosterol 14-alpha-demethylase	/	0.471
4eos	1RO	Cyclin-dependent kinase 2	2.7.11.22	0.471
1byg	STU	Tyrosine-protein kinase CSK	/	0.470
2qd4	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.470
3dle	GFA	Gag-Pol polyprotein	2.7.7.49	0.470
3njo	P2M	Abscisic acid receptor PYR1	/	0.470
1bwl	FMN	NADPH dehydrogenase 1	1.6.99.1	0.469
2ovm	AS0	Progesterone receptor	/	0.469
2xvv	9DN	Serum albumin	/	0.469
4lmu	QUE	Serine/threonine-protein kinase pim-1	2.7.11.1	0.469
2h96	893	Mitogen-activated protein kinase 8	2.7.11.24	0.468
2i4z	DRH	Peroxisome proliferator-activated receptor gamma	/	0.468
2p33	J07	Mitogen-activated protein kinase 10	2.7.11.24	0.468
3a78	3EV	Vitamin D3 receptor	/	0.468
3c3d	FO1	2-phospho-L-lactate transferase	/	0.468
3k47	D09	Dihydrofolate reductase	1.5.1.3	0.468
3p8i	FMN	Pentaerythritol tetranitrate reductase	/	0.468
3r34	COA	4-hydroxybenzoyl-CoA thioesterase	3.1.2.23	0.468
3ssn	MVI	Mycinamicin VI 2''-O-methyltransferase	/	0.468
4ia2	BIV	Vitamin D3 receptor A	/	0.468
4mv8	ACP	Biotin carboxylase	6.3.4.14	0.468
1x8l	OXR	Retinol dehydratase	/	0.467
3hz1	42C	Heat shock protein HSP 90-alpha	/	0.467
3oaf	OAG	Dihydrofolate reductase	1.5.1.3	0.467
3tk3	CPZ	Cytochrome P450 2B4	1.14.14.1	0.467
4fgg	0U5	Dihydrofolate reductase	1.5.1.3	0.467
4iwq	1FV	Serine/threonine-protein kinase TBK1	2.7.11.1	0.467
4j03	FVS	Bifunctional epoxide hydrolase 2	3.1.3.76	0.467
1fml	RTL	Retinol dehydratase	/	0.466
1rfv	ADP	Pyridoxal kinase	2.7.1.35	0.466
2chx	090	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.466
3cse	N22	Uncharacterized protein	/	0.466
3inw	JZB	Heat shock protein HSP 90-alpha	/	0.466
4anx	534	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.466
4dgo	0JW	Casein kinase II subunit alpha	2.7.11.1	0.466
4hle	17V	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.466
1kqw	RTL	Cellular retinol-binding protein type II	/	0.465
1y0s	331	Peroxisome proliferator-activated receptor delta	/	0.465
2ic3	HBY	Gag-Pol polyprotein	2.7.7.49	0.465
3a4o	STU	Tyrosine-protein kinase Lyn	2.7.10.2	0.465
3jzi	JZL	Biotin carboxylase	6.3.4.14	0.465
3r04	UNQ	Serine/threonine-protein kinase pim-1	2.7.11.1	0.465
4mwh	ATP	Casein kinase II subunit alpha	2.7.11.1	0.465
5ecc	NAP	Dehydrofolate reductase type I	/	0.465
1iyz	NDP	Probable quinone oxidoreductase	/	0.464
1uym	PU3	Heat shock protein HSP 90-beta	/	0.464
3c0i	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.464
4ia3	BIV	Vitamin D3 receptor A	/	0.464
4iar	ERM	5-hydroxytryptamine receptor 1B	/	0.464
4lfi	GNP	Casein kinase II subunit alpha	2.7.11.1	0.464
1ndz	FR5	Adenosine deaminase	3.5.4.4	0.463
1ojt	FAD	Dihydrolipoyl dehydrogenase	/	0.463
1q97	ATP	Serine/threonine-protein kinase SKY1	2.7.11.1	0.463
2q66	ATP	Poly(A) polymerase	2.7.7.19	0.463
3bc3	OPT	Cathepsin L1	3.4.22.15	0.463
3c0g	3AM	Peripheral plasma membrane protein CASK	2.7.11.1	0.463
3oqf	S51	Renin	3.4.23.15	0.463
4bzo	676	Serine/threonine-protein kinase pim-1	2.7.11.1	0.463
4ia1	BIV	Vitamin D3 receptor A	/	0.463
4k2x	FAD	Polyketide oxygenase/hydroxylase	/	0.463
4nyw	2O3	CREB-binding protein	/	0.463
4pkl	1GH	Uncharacterized protein	/	0.463
1fdw	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.462
1itz	TPP	Transketolase, chloroplastic	2.2.1.1	0.462
1jpa	ANP	Ephrin type-B receptor 2	2.7.10.1	0.462
1uyh	PU0	Heat shock protein HSP 90-alpha	/	0.462
3jpv	1DR	Serine/threonine-protein kinase pim-1	2.7.11.1	0.462
3mpi	FAD	Glutaryl-CoA dehydrogenase	1.3.99.32	0.462
3u8h	BHP	Phospholipase A2, membrane associated	/	0.462
4awp	99A	Heat shock protein HSP 90-alpha	/	0.462
4fhk	0U0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.462
4i0t	1B6	Tyrosine-protein kinase SYK	2.7.10.2	0.462
1ay0	TPP	Transketolase 1	2.2.1.1	0.461
1zq9	SAM	Probable dimethyladenosine transferase	/	0.461
2j2i	LY4	Serine/threonine-protein kinase pim-1	2.7.11.1	0.461
2y46	MIV	Mycinamicin IV hydroxylase/epoxidase	/	0.461
3bgq	VX2	Serine/threonine-protein kinase pim-1	2.7.11.1	0.461
3eek	53S	Uncharacterized protein	/	0.461
3kyt	HC2	Nuclear receptor ROR-gamma	/	0.461
3qlz	QLZ	Uncharacterized protein	/	0.461
4a81	DXC	Major pollen allergen Bet v 1-A	/	0.461
4ezk	0SD	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.461
4f1s	F1S	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.461
4fog	C2F	Thymidylate synthase ThyA	/	0.461
4g2f	C07	Ephrin type-A receptor 3	2.7.10.1	0.461
4ite	TEY	Vitamin D3 receptor	/	0.461
5d7p	OCZ	NAD-dependent protein deacetylase sirtuin-2	3.5.1	0.461
3rey	XAC	Adenosine receptor A2a	/	0.461
1uy9	PU6	Heat shock protein HSP 90-alpha	/	0.460
2wi7	2KL	Heat shock protein HSP 90-alpha	/	0.460
3pxy	JWS	Cyclin-dependent kinase 2	2.7.11.22	0.460
3vrw	YS5	Vitamin D3 receptor	/	0.460
3vt5	YI2	Vitamin D3 receptor	/	0.460
4bbx	LKF	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.460
4kz0	1UJ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.460
4r1l	ADP	Phenylacetate-coenzyme A ligase	/	0.460
4r20	AER	Cytochrome P450 family 17 polypeptide 2	/	0.460
4xe6	06U	Dihydrofolate reductase	1.5.1.3	0.460
1dhj	MTX	Dihydrofolate reductase	1.5.1.3	0.459
1i7i	AZ2	Peroxisome proliferator-activated receptor gamma	/	0.459
1rkh	VD2	Vitamin D3 receptor	/	0.459
1s19	MC9	Vitamin D3 receptor	/	0.459
1xom	CIO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.459
1ykd	CMP	Adenylate cyclase	/	0.459
2j3j	HC4	NADPH-dependent oxidoreductase 2-alkenal reductase	1.3.1.74	0.459
2y98	MIV	Mycinamicin IV hydroxylase/epoxidase	/	0.459
3cyl	VIT	Basic phospholipase A2 homolog piratoxin-2	/	0.459
3ibq	ATP	Pyridoxal kinase	/	0.459
3pm9	FAD	Putative oxidoreductase	/	0.459
4dij	BLF	E3 ubiquitin-protein ligase Mdm2	6.3.2	0.459
4i8v	BHF	Cytochrome P450 1A1	1.14.14.1	0.459
4rr7	A3S	Probable threonine--tRNA ligase 2	6.1.1.3	0.459
4wh3	ATP	N-acetylhexosamine 1-kinase	2.7.1.162	0.459
5a4k	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.459
1siq	FAD	Glutaryl-CoA dehydrogenase, mitochondrial	1.3.8.6	0.458
1vrq	FON	Subunit alpha of sarocosine oxidase	/	0.458
2a1t	FAD	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	1.3.8.7	0.458
2ham	C33	Vitamin D3 receptor	/	0.458
2ivn	ANP	tRNA N6-adenosine threonylcarbamoyltransferase	/	0.458
2j14	GNI	Peroxisome proliferator-activated receptor delta	/	0.458
2x7h	PFN	Prostaglandin reductase 3	1	0.458
3ey4	352	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.458
3gob	HXX	DdmC	/	0.458
3lj3	WYE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.458
3v9y	24L	Peroxisome proliferator-activated receptor gamma	/	0.458
4anu	EM7	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.458
4cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.458
4fjy	FJY	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.458
1daw	ANP	Casein kinase II subunit alpha	2.7.11.1	0.457
1knu	YPA	Peroxisome proliferator-activated receptor gamma	/	0.457
1rdt	570	Peroxisome proliferator-activated receptor gamma	/	0.457
1wlv	COA	Phenylacetic acid degradation protein PaaI	/	0.457
2has	C3O	Vitamin D3 receptor	/	0.457
2wuf	KEM	4,5:9,10-diseco-3-hydroxy-5,9,17-trioxoandrosta-1(10),2-diene-4-oate hydrolase	3.7.1.17	0.457
2y6f	M9F	Isopenicillin N synthase	1.21.3.1	0.457
2zba	ZBA	Trichothecene 3-O-acetyltransferase	/	0.457
3c1t	MYC	Dihydroflavonol 4-reductase	1.1.1.219	0.457
3q9b	B3N	Acetylpolyamine amidohydrolase	/	0.457
4h95	06U	Dihydrofolate reductase	1.5.1.3	0.457
4jlc	SU6	Serine/threonine-protein kinase TBK1	2.7.11.1	0.457
4xiw	AZM	Carbonic anhydrase, alpha type	/	0.457
5ii2	LU2	Protein polybromo-1	/	0.457
1bws	NDP	GDP-L-fucose synthase	/	0.456
1d4a	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.456
1h69	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.456
1u1c	BAU	Uridine phosphorylase	2.4.2.3	0.456
1xdd	AAY	Integrin alpha-L	/	0.456
2bun	FAD	AppA protein	/	0.456
2o4r	VD5	Vitamin D3 receptor	/	0.456
2qk8	MTX	Dihydrofolate reductase	/	0.456
2w6m	OA1	Biotin carboxylase	6.3.4.14	0.456
2xik	J60	Serine/threonine-protein kinase 25	2.7.11.1	0.456
3br3	ET	HTH-type transcriptional regulator QacR	/	0.456
3ffi	3OB	Gag-Pol polyprotein	2.7.7.49	0.456
3slk	NDP	Polyketide synthase extender module 2	/	0.456
3w0a	DS5	Vitamin D3 receptor	/	0.456
4c59	FEF	Cyclin-G-associated kinase	2.7.11.1	0.456
4fi1	ATP	Casein kinase II subunit alpha	2.7.11.1	0.456
4g1y	0VO	Vitamin D3 receptor A	/	0.456
4ge7	0K5	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.456
4ho8	THM	Glucose-1-phosphate thymidylyltransferase	/	0.456
4iwo	1H4	Serine/threonine-protein kinase TBK1	2.7.11.1	0.456
1ie4	T44	Transthyretin	/	0.455
1rfu	ADP	Pyridoxal kinase	2.7.1.35	0.455
2c3i	IYZ	Serine/threonine-protein kinase pim-1	2.7.11.1	0.455
2c3q	GTX	Glutathione S-transferase theta-1	2.5.1.18	0.455
2y1o	T26	UDP-N-acetylmuramoylalanine--D-glutamate ligase	6.3.2.9	0.455
3mnr	SD1	Heat shock protein HSP 90-alpha	/	0.455
3mtf	A3F	Activin receptor type-1	2.7.11.30	0.455
3nga	3NG	Casein kinase II subunit alpha	2.7.11.1	0.455
3uyt	0CK	Casein kinase I isoform delta	2.7.11.1	0.455
3vt9	YI4	Vitamin D3 receptor	/	0.455
3we4	5FI	Ribosomal protein S6 kinase beta-1	2.7.11.1	0.455
3zm4	22T	Dual specificity mitogen-activated protein kinase kinase 1	2.7.12.2	0.455
3zw3	ZW3	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.455
4anw	O92	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.455
4bfp	SWY	Tankyrase-2	2.4.2.30	0.455
4e96	0NS	Bromodomain-containing protein 4	/	0.455
4ezl	0SE	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.455
4kak	06U	Dihydrofolate reductase	1.5.1.3	0.455
1dhr	NAD	Dihydropteridine reductase	1.5.1.34	0.454
1fmj	RTL	Retinol dehydratase	/	0.454
1oiy	N41	Cyclin-dependent kinase 2	2.7.11.22	0.454
1q4t	4CO	4-hydroxybenzoyl-CoA thioesterase	3.1.2.23	0.454
1qpd	STU	Tyrosine-protein kinase Lck	2.7.10.2	0.454
1ung	ALH	Cyclin-dependent-like kinase 5	2.7.11.1	0.454
1uyd	PU8	Heat shock protein HSP 90-alpha	/	0.454
1zeo	C01	Peroxisome proliferator-activated receptor gamma	/	0.454
1zid	ZID	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.454
2e9u	A25	Serine/threonine-protein kinase Chk1	2.7.11.1	0.454
2fgk	ATP	Alpha-hemolysin translocation ATP-binding protein HlyB	/	0.454
2izr	BRK	Casein kinase I isoform gamma-3	2.7.11.1	0.454
2r5n	TPP	Transketolase 1	/	0.454
2uxu	NAR	HTH-type transcriptional regulator TtgR	/	0.454
3b9l	AZZ	Serum albumin	/	0.454
3l8p	0CE	Angiopoietin-1 receptor	2.7.10.1	0.454
3pm1	ET	HTH-type transcriptional regulator QacR	/	0.454
3q9z	TXQ	Casein kinase II subunit alpha	2.7.11.1	0.454
4d0l	093	Phosphatidylinositol 4-kinase beta	2.7.1.67	0.454
4e1z	0MX	Non-receptor tyrosine-protein kinase TYK2	2.7.10.2	0.454
4ea1	3RX	Dehydrosqualene synthase	/	0.454
4eiy	ZMA	Adenosine receptor A2a	/	0.454
4gi2	NAP	Crotonyl-CoA carboxylase/reductase	/	0.454
4h98	14Q	Uncharacterized protein	/	0.454
4jia	1K3	Tyrosine-protein kinase JAK2	/	0.454
4yr9	NAD	L-threonine 3-dehydrogenase, mitochondrial	1.1.1.103	0.454
5dfc	EAM	Bromodomain-containing protein 2	/	0.454
1diu	BDM	Dihydrofolate reductase	1.5.1.3	0.453
1uy8	PU5	Heat shock protein HSP 90-alpha	/	0.453
1ysx	4EB	Serum albumin	/	0.453
2i4q	UA4	Renin	3.4.23.15	0.453
2p4y	C03	Peroxisome proliferator-activated receptor gamma	/	0.453
2tps	TPS	Thiamine-phosphate synthase	/	0.453
2xvw	9NR	Serum albumin	/	0.453
2y8q	ADP	5'-AMP-activated protein kinase subunit gamma-1	/	0.453
2z2w	770	Wee1-like protein kinase	2.7.10.2	0.453
2znp	K55	Peroxisome proliferator-activated receptor delta	/	0.453
3at4	CCK	Casein kinase II subunit alpha	2.7.11.1	0.453
3irm	1CY	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.453
3jzf	JZK	Biotin carboxylase	6.3.4.14	0.453
3mfu	ANP	Peripheral plasma membrane protein CASK	2.7.11.1	0.453
3pe2	E1B	Casein kinase II subunit alpha	2.7.11.1	0.453
4c58	824	Cyclin-G-associated kinase	2.7.11.1	0.453
4ele	31I	Dihydrofolate reductase	/	0.453
4ia7	BIV	Vitamin D3 receptor A	/	0.453
4ixg	IXG	Dihydrofolate reductase	1.5.1.3	0.453
4n70	2HX	Serine/threonine-protein kinase pim-1	2.7.11.1	0.453
4rup	H97	Vitamin D3 receptor A	/	0.453
4xcv	NDP	Probable hydroxyacid dehydrogenase protein	/	0.453
1iid	NHM	Glycylpeptide N-tetradecanoyltransferase	2.3.1.97	0.452
1l2j	ETC	Estrogen receptor beta	/	0.452
1s3y	TQT	Dihydrofolate reductase	1.5.1.3	0.452
2e9d	B76	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	2.5.1.31	0.452
2vn0	TDZ	Cytochrome P450 2C8	/	0.452
2ywv	ADP	Phosphoribosylaminoimidazole-succinocarboxamide synthase	/	0.452
3fql	79Z	Genome polyprotein	2.7.7.48	0.452
3gbk	2PQ	Peroxisome proliferator-activated receptor gamma	/	0.452
3i0r	RT3	Gag-Pol polyprotein	2.7.7.49	0.452
3jxw	LXG	Serine/threonine-protein kinase pim-1	2.7.11.1	0.452
3qly	55V	Uncharacterized protein	/	0.452
3t8x	T8X	T-cell surface glycoprotein CD1b	/	0.452
4aox	FAD	Steroid monooxygenase	/	0.452
4jaz	STL	Peroxisome proliferator-activated receptor gamma	/	0.452
4r8q	ADP	Mitotic checkpoint serine/threonine-protein kinase BUB1	2.7.11.1	0.452
4zoh	FAD	Putative oxidoreductase FAD-binding subunit	/	0.452
1bsv	NDP	GDP-L-fucose synthase	/	0.451
1j3i	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.451
1nq7	ARL	Nuclear receptor ROR-beta	/	0.451
2i0y	5CN	Macrophage colony-stimulating factor 1 receptor	2.7.10.1	0.451
2nry	STU	Interleukin-1 receptor-associated kinase 4	2.7.11.1	0.451
2ouu	35G	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.451
2pyw	ADP	Methylthioribose kinase	2.7.1.100	0.451
2vf0	F89	Thymidylate synthase	/	0.451
3eej	53R	Uncharacterized protein	/	0.451
3h0a	9RA	Retinoic acid receptor RXR-alpha	/	0.451
3lan	KBT	Gag-Pol polyprotein	2.7.7.49	0.451
3mfs	ANP	Peripheral plasma membrane protein CASK	2.7.11.1	0.451
3qk0	QK0	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.451
3vbq	0F5	Serine/threonine-protein kinase pim-1	2.7.11.1	0.451
3wow	ANP	Casein kinase II subunit alpha	2.7.11.1	0.451
4awo	99B	Heat shock protein HSP 90-alpha	/	0.451
4idv	13V	Mitogen-activated protein kinase kinase kinase 14	2.7.11.25	0.451
4kfj	1R0	Dihydrofolate reductase	1.5.1.3	0.451
4m69	ANP	Receptor-interacting serine/threonine-protein kinase 3	2.7.11.1	0.451
4mxx	DB8	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.451
4nh8	2LC	Heat shock protein HSP 90-alpha	/	0.451
4twp	AXI	Tyrosine-protein kinase ABL1	2.7.10.2	0.451
5iua	6DX	Adenosine receptor A2a	/	0.451
1kbq	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.450
1m78	NDP	Dihydrofolate reductase	1.5.1.3	0.450
1xon	PIL	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.450
1yw2	PGJ	Mitogen-activated protein kinase 14	/	0.450
2e9v	85A	Serine/threonine-protein kinase Chk1	2.7.11.1	0.450
2g1p	SAH	DNA adenine methylase	2.1.1.72	0.450
2xj2	985	Serine/threonine-protein kinase pim-1	2.7.11.1	0.450
2zjw	REF	Casein kinase II subunit alpha	2.7.11.1	0.450
2zru	FMN	Isopentenyl-diphosphate delta-isomerase	/	0.450
3dol	GWI	Pol protein	/	0.450
3ns2	PYV	Abscisic acid receptor PYL2	/	0.450
3oqu	A8S	Abscisic acid receptor PYL9	/	0.450
3r02	UNM	Serine/threonine-protein kinase pim-1	2.7.11.1	0.450
3r32	4CO	4-hydroxybenzoyl-CoA thioesterase	3.1.2.23	0.450
3ruk	AER	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.450
3u4u	LNH	Casein kinase II subunit alpha	2.7.11.1	0.450
3zhv	TDW	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.450
4dph	P65	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.450
4flh	14K	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.450
4hw3	19G	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.450
4l2y	XXK	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform	/	0.450
4mlh	VO2	Glucokinase	2.7.1.2	0.450
1blz	ACV	Isopenicillin N synthase	1.21.3.1	0.449
1dhi	MTX	Dihydrofolate reductase	1.5.1.3	0.449
1dr4	HBI	Dihydrofolate reductase	1.5.1.3	0.449
1e7v	LY2	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.449
1k6t	XN1	Gag-Pol polyprotein	3.4.23.16	0.449
1kbo	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.449
1qxl	FR8	Adenosine deaminase	3.5.4.4	0.449
1y60	H4M	5,6,7,8-tetrahydromethanopterin hydro-lyase	4.2.1.147	0.449
2dvl	FAD	Acyl-CoA dehydrogenase	/	0.449
2hw2	RFP	Rifampin ADP-ribosyl transferase	/	0.449
2uxo	TAC	HTH-type transcriptional regulator TtgR	/	0.449
2vcm	M11	Isopenicillin N synthase	1.21.3.1	0.449
2vg7	NNI	Gag-Pol polyprotein	2.7.7.49	0.449
2wgj	VGH	Hepatocyte growth factor receptor	2.7.10.1	0.449
3ddw	055	Glycogen phosphorylase, liver form	2.4.1.1	0.449
3q44	D50	M1 family aminopeptidase	3.4.11	0.449
3qj5	022	Alcohol dehydrogenase class-3	1.1.1.1	0.449
3s2a	2NQ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.449
4deg	0JJ	Hepatocyte growth factor receptor	2.7.10.1	0.449
4foc	0UU	ALK tyrosine kinase receptor	2.7.10.1	0.449
4gfo	0X2	Non-receptor tyrosine-protein kinase TYK2	2.7.10.2	0.449
4gk2	L66	Ephrin type-A receptor 3	2.7.10.1	0.449
4kd7	9DR	Dihydrofolate reductase	1.5.1.3	0.449
4nra	2LW	Bromodomain adjacent to zinc finger domain protein 2B	/	0.449
5dt3	ATP	Aurora kinase A	2.7.11.1	0.449
1bim	0QB	Renin	3.4.23.15	0.448
1db1	VDX	Vitamin D3 receptor	/	0.448
1dyj	DDF	Dihydrofolate reductase	1.5.1.3	0.448
1h1s	4SP	Cyclin-dependent kinase 2	2.7.11.22	0.448
1rf7	DHF	Dihydrofolate reductase	1.5.1.3	0.448
1rx7	FOL	Dihydrofolate reductase	1.5.1.3	0.448
1uy7	PU4	Heat shock protein HSP 90-alpha	/	0.448
1uyk	PUX	Heat shock protein HSP 90-alpha	/	0.448
1xef	ATP	Alpha-hemolysin translocation ATP-binding protein HlyB	/	0.448
1zrz	BI1	Protein kinase C iota type	2.7.11.13	0.448
2c27	ACO	Mycothiol acetyltransferase	2.3.1.189	0.448
2cd2	FOL	Dihydrofolate reductase	1.5.1.3	0.448
2cdz	23D	Serine/threonine-protein kinase PAK 4	2.7.11.1	0.448
2cgw	3C3	Serine/threonine-protein kinase Chk1	2.7.11.1	0.448
2cig	1DG	Dihydrofolate reductase	1.5.1.3	0.448
2fwy	H64	Heat shock protein HSP 90-alpha	/	0.448
2giv	ACO	Histone acetyltransferase KAT8	/	0.448
2hb8	MVD	Vitamin D3 receptor	/	0.448
2ivu	ZD6	Proto-oncogene tyrosine-protein kinase receptor Ret	2.7.10.1	0.448
2vwu	7X1	Ephrin type-B receptor 4	2.7.10.1	0.448
2w0b	CMW	Lanosterol 14-alpha demethylase	1.14.13.70	0.448
2ze2	T27	Gag-Pol polyprotein	2.7.7.49	0.448
3a0i	AJI	Glucokinase	2.7.1.2	0.448
3be9	P04	Casein kinase II subunit alpha	2.7.11.1	0.448
3fgo	CZA	Sarcoplasmic/endoplasmic reticulum calcium ATPase 1	3.6.3.8	0.448
3m7r	VDX	Vitamin D3 receptor	/	0.448
3ofm	4B0	Casein kinase II subunit alpha'	2.7.11.1	0.448
3qfv	NM7	Serine/threonine-protein kinase MRCK beta	2.7.11.1	0.448
3sp6	IL2	Peroxisome proliferator-activated receptor alpha	/	0.448
3sp9	IL2	Peroxisome proliferator-activated receptor delta	/	0.448
4aoi	4K0	Hepatocyte growth factor receptor	2.7.10.1	0.448
4dym	IYZ	Activin receptor type-1	2.7.11.30	0.448
4ejh	0QA	Cytochrome P450 2A13	1.14.14.1	0.448
4ezj	0SC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.448
4fk8	FAD	Ferredoxin--NADP reductase	/	0.448
4l42	5FI	Ribosomal protein S6 kinase beta-1	2.7.11.1	0.448
4o0w	ADN	Aurora kinase A	2.7.11.1	0.448
4ocv	ANP	Aminoglycoside phosphotransferase	/	0.448
4xgx	ADP	FAD:protein FMN transferase	/	0.448
4zas	TYD	CalS13	/	0.448
5e8x	STU	TGF-beta receptor type-1	2.7.11.30	0.448
1e9h	INR	Cyclin-dependent kinase 2	2.7.11.22	0.447
1jol	FFO	Dihydrofolate reductase	1.5.1.3	0.447
1s0z	EB1	Vitamin D3 receptor	/	0.447
1u54	ACP	Activated CDC42 kinase 1	/	0.447
2c0i	L1G	Tyrosine-protein kinase HCK	2.7.10.2	0.447
2cy2	ACO	Probable acetyltransferase	/	0.447
2jc6	QPP	Calcium/calmodulin-dependent protein kinase type 1D	2.7.11.17	0.447
2pzi	AXX	Serine/threonine-protein kinase PknG	2.7.11.1	0.447
2v5a	LZL	Biotin carboxylase	6.3.4.14	0.447
2w3v	TOP	Dihydrofolate reductase	/	0.447
3e6o	A55	Nitric oxide synthase, inducible	1.14.13.39	0.447
3flk	NAI	Tartrate dehydrogenase/decarboxylase	1.1.1.93	0.447
3fzn	D7K	Benzoylformate decarboxylase	4.1.1.7	0.447
3hxb	BD5	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.447
3inv	C50	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.447
3iqz	H4M	F420-dependent methylenetetrahydromethanopterin dehydrogenase	1.5.98.1	0.447
3oqk	S52	Renin	3.4.23.15	0.447
3pj8	404	Cyclin-dependent kinase 2	2.7.11.22	0.447
3qpo	PFR	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.447
4bb3	KKA	Isopenicillin N synthase	1.21.3.1	0.447
4bfv	ZVV	Pantothenate kinase	2.7.1.33	0.447
4bkz	1WS	Maternal embryonic leucine zipper kinase	2.7.11.1	0.447
4dit	0KD	Glycogen synthase kinase-3 beta	2.7.11.26	0.447
4i22	IRE	Epidermal growth factor receptor	2.7.10.1	0.447
4jq8	KJ8	Epidermal growth factor receptor	2.7.10.1	0.447
4ly9	1YY	Glucokinase regulatory protein	/	0.447
4nkv	AER	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.447
4oau	ADP	2-5A-dependent ribonuclease	3.1.26	0.447
4ruo	BIV	Vitamin D3 receptor A	/	0.447
4wh2	ADP	N-acetylhexosamine 1-kinase	2.7.1.162	0.447
1cm8	ANP	Mitogen-activated protein kinase 12	/	0.446
1g4s	TPS	Thiamine-phosphate synthase	/	0.446
1hzj	UD1	UDP-glucose 4-epimerase	/	0.446
1ie8	KH1	Vitamin D3 receptor	/	0.446
1m2r	MNY	Casein kinase II subunit alpha	2.7.11.1	0.446
1nyx	DRF	Peroxisome proliferator-activated receptor gamma	/	0.446
2abb	FMN	Pentaerythritol tetranitrate reductase	/	0.446
2acw	UPG	Glycosyltransferase	/	0.446
2ath	3EA	Peroxisome proliferator-activated receptor gamma	/	0.446
2bak	AQZ	Mitogen-activated protein kinase 14	/	0.446
2c6t	DT5	Cyclin-dependent kinase 2	2.7.11.22	0.446
2fzh	DH1	Dihydrofolate reductase	1.5.1.3	0.446
2fzi	DH3	Dihydrofolate reductase	1.5.1.3	0.446
2hfp	NSI	Peroxisome proliferator-activated receptor gamma	/	0.446
2iko	7IG	Renin	3.4.23.15	0.446
2pvn	P63	Casein kinase II subunit alpha	2.7.11.1	0.446
2q59	240	Peroxisome proliferator-activated receptor gamma	/	0.446
3czr	3CZ	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.446
3dog	NNN	Cyclin-dependent kinase 2	2.7.11.22	0.446
3fl8	RAR	Dihydrofolate reductase	/	0.446
3lpb	NVB	Tyrosine-protein kinase JAK2	/	0.446
3p3z	P3Z	Putative cytochrome P450	/	0.446
3td8	D2R	Dihydrofolate reductase	1.5.1.3	0.446
3zuy	TCH	Transporter	/	0.446
4a9y	AQZ	Mitogen-activated protein kinase 14	/	0.446
4awq	592	Heat shock protein HSP 90-alpha	/	0.446
4bib	IEO	Mitogen-activated protein kinase kinase kinase 5	2.7.11.25	0.446
4dpd	DHF	Bifunctional dihydrofolate reductase-thymidylate synthase	/	0.446
4f7l	0SO	Cyclin-dependent kinase 8	2.7.11.22	0.446
4fv7	E94	Mitogen-activated protein kinase 1	2.7.11.24	0.446
4kb8	1QN	Casein kinase I isoform delta	2.7.11.1	0.446
4riy	ADP	Epidermal growth factor receptor	2.7.10.1	0.446
4xiv	ACP	Chemotaxis protein CheA	2.7.13.3	0.446
5ar4	SB2	Receptor-interacting serine/threonine-protein kinase 2	2.7.11.1	0.446
5dqr	FAD	7-hydroxymethyl chlorophyll a reductase, chloroplastic	1.17.7.2	0.446
1e7q	NAP	GDP-L-fucose synthase	/	0.445
1e8x	ATP	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.445
1jio	DEB	6-deoxyerythronolide B hydroxylase	/	0.445
1kkq	471	Peroxisome proliferator-activated receptor alpha	/	0.445
1lsj	NAD	Hydroxyacyl-coenzyme A dehydrogenase, mitochondrial	1.1.1.35	0.445
1o5r	FR9	Adenosine deaminase	3.5.4.4	0.445
1om1	IQA	Casein kinase II subunit alpha	2.7.11.1	0.445
1q8y	ADP	Serine/threonine-protein kinase SKY1	2.7.11.1	0.445
1sr7	MOF	Progesterone receptor	/	0.445
1upw	444	Oxysterols receptor LXR-beta	/	0.445
1uyf	PU1	Heat shock protein HSP 90-alpha	/	0.445
1xkk	FMM	Epidermal growth factor receptor	2.7.10.1	0.445
1zdw	FLV	Prenyltransferase	/	0.445
2c96	ATP	Psp operon transcriptional activator	/	0.445
2ds1	1CD	Cyclin-dependent kinase 2	2.7.11.22	0.445
2dsg	SAH	Diphthine synthase	/	0.445
2fzj	DH3	Dihydrofolate reductase	1.5.1.3	0.445
2i0e	PDS	Protein kinase C beta type	2.7.11.13	0.445
2lfo	GCH	Fatty acid-binding protein, liver	/	0.445
2m56	CAM	Camphor 5-monooxygenase	1.14.15.1	0.445
2nn7	M29	Carbonic anhydrase 1	4.2.1.1	0.445
2oax	SNL	Mineralocorticoid receptor	/	0.445
2obx	INI	6,7-dimethyl-8-ribityllumazine synthase 2	2.5.1.78	0.445
2ohv	NHL	Glutamate racemase	/	0.445
2qe4	JJ3	Estrogen receptor	/	0.445
2v58	LZJ	Biotin carboxylase	6.3.4.14	0.445
2wd8	VGF	Pteridine reductase	/	0.445
2wou	ZZF	TGF-beta receptor type-1	2.7.11.30	0.445
3bhy	7CP	Death-associated protein kinase 3	/	0.445
3dds	26B	Glycogen phosphorylase, liver form	2.4.1.1	0.445
3dga	NDP	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.445
3igo	ANP	Calmodulin-domain protein kinase 1, putative	/	0.445
3il1	B5D	Glutamate receptor 2	/	0.445
3ozd	4CT	S-methyl-5'-thioadenosine phosphorylase	/	0.445
3pz2	3PZ	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.445
3qiy	QI1	Botulinum neurotoxin type A	3.4.24.69	0.445
3r3d	4CO	4-hydroxybenzoyl-CoA thioesterase	3.1.2.23	0.445
3w4y	FAD	Mitochondrial FAD-linked sulfhydryl oxidase ERV1	1.8.3.2	0.445
4ajd	F04	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.445
4bcm	T7Z	Cyclin-dependent kinase 2	2.7.11.22	0.445
4bge	PYW	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.445
4bie	IE6	Mitogen-activated protein kinase kinase kinase 5	2.7.11.25	0.445
4bj9	UHB	Tankyrase-2	2.4.2.30	0.445
4ead	0NP	Thymidine phosphorylase	2.4.2.4	0.445
4efu	EFU	Heat shock protein HSP 90-alpha	/	0.445
4elb	34S	Dihydrofolate reductase	/	0.445
4kbn	25U	Dihydrofolate reductase	1.5.1.3	0.445
4mfb	29T	Gag-Pol polyprotein	2.7.7.49	0.445
4rtj	SFG	DNA adenine methylase	2.1.1.72	0.445
5ajq	DB8	Serine/threonine-protein kinase 10	2.7.11.1	0.445
5ikr	ID8	Prostaglandin G/H synthase 2	1.14.99.1	0.445
3sn6	P0G	Beta-2 adrenergic receptor	/	0.445
1e90	MYC	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.444
1eio	GCH	Gastrotropin	/	0.444
1k6c	MK1	Gag-Pol polyprotein	3.4.23.16	0.444
1kzj	CB3	Thymidylate synthase	/	0.444
1m2q	MNX	Casein kinase II subunit alpha	2.7.11.1	0.444
1oya	FMN	NADPH dehydrogenase 1	1.6.99.1	0.444
1y57	MPZ	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.444
2c6h	PXI	Cytochrome P450 monooxygenase PikC	/	0.444
2gtk	208	Peroxisome proliferator-activated receptor gamma	/	0.444
2ilt	NN1	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.444
2nru	T12	Interleukin-1 receptor-associated kinase 4	2.7.11.1	0.444
2obj	VRV	Serine/threonine-protein kinase pim-1	2.7.11.1	0.444
2w6q	OA5	Biotin carboxylase	6.3.4.14	0.444
2x8i	X8I	Serine/threonine-protein kinase Chk1	2.7.11.1	0.444
2ylx	FAD	Phenylacetone monooxygenase	1.14.13.92	0.444
2ym2	FAD	Phenylacetone monooxygenase	1.14.13.92	0.444
2z3u	CRR	Cytochrome P450	/	0.444
2znq	401	Peroxisome proliferator-activated receptor delta	/	0.444
3bgp	VX1	Serine/threonine-protein kinase pim-1	2.7.11.1	0.444
3cy2	MB9	Serine/threonine-protein kinase pim-1	2.7.11.1	0.444
3d3e	D3E	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.444
3fz1	B98	Cyclin-dependent kinase 2	2.7.11.22	0.444
3g5s	FAD	Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO	/	0.444
3gco	VAL_TYR_GLN_PHE	Serine endoprotease DegS	3.4.21.107	0.444
3hz1	37D	Heat shock protein HSP 90-alpha	/	0.444
3l1s	Z92	Glycogen synthase kinase-3 beta	2.7.11.26	0.444
3nsz	ANP	Casein kinase II subunit alpha	2.7.11.1	0.444
3o56	ZG1	cAMP-specific 3',5'-cyclic phosphodiesterase 4B	3.1.4.53	0.444
3qf9	NM8	Serine/threonine-protein kinase pim-1	2.7.11.1	0.444
3s7a	684	Dihydrofolate reductase	1.5.1.3	0.444
3zhs	TD6	Multifunctional 2-oxoglutarate metabolism enzyme	1.2.4.2	0.444
4b7d	QLE	Cytochrome P450 monooxygenase PikC	/	0.444
4bgg	844	Activin receptor type-1	2.7.11.30	0.444
4bix	ADP	Sensor histidine kinase CpxA	/	0.444
4dpw	AGS	Mevalonate diphosphate decarboxylase	/	0.444
4dqu	NAI	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.444
4elf	35I	Dihydrofolate reductase	/	0.444
4gj3	0XP	Non-receptor tyrosine-protein kinase TYK2	2.7.10.2	0.444
4h96	14Q	Dihydrofolate reductase	1.5.1.3	0.444
4i0s	1B5	Tyrosine-protein kinase SYK	2.7.10.2	0.444
4ib4	ERM	5-hydroxytryptamine receptor 2B	/	0.444
4jb1	FAD	UDP-N-acetylenolpyruvoylglucosamine reductase	/	0.444
4jqe	ANP	Casein kinase II subunit alpha	2.7.11.1	0.444
4jr7	GNP	Casein kinase II subunit alpha	2.7.11.1	0.444
4l3l	5FI	Ribosomal protein S6 kinase beta-1	2.7.11.1	0.444
4oae	CLM	Uncharacterized protein	/	0.444
4rqv	ATP	3-phosphoinositide-dependent protein kinase 1	2.7.11.1	0.444
4rrh	A3S	Probable threonine--tRNA ligase 2	6.1.1.3	0.444
4z61	ILE_THR_GLN_TYS_TYS	Phytosulfokine receptor 1	2.7.11.1	0.444
5cvh	ADP	Casein kinase II subunit alpha	2.7.11.1	0.444
5drd	ATP	Aurora kinase A	2.7.11.1	0.444
5e8w	STU	TGF-beta receptor type-1	2.7.11.30	0.444
1e8z	STU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.443
1fm7	DFV	Chalcone--flavonone isomerase 1	5.5.1.6	0.443
1fp1	HCC	Isoliquiritigenin 2'-O-methyltransferase	/	0.443
1ly3	COG	Dihydrofolate reductase	1.5.1.3	0.443
1ndy	FR3	Adenosine deaminase	3.5.4.4	0.443
1tw2	ERT	Carminomycin 4-O-methyltransferase DnrK	2.1.1.292	0.443
2ejv	NAD	L-threonine 3-dehydrogenase	/	0.443
2hrc	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.443
2jkk	BI9	Focal adhesion kinase 1	2.7.10.2	0.443
2zbz	VDX	Vitamin D3 dihydroxylase	/	0.443
3d8v	UD1	Bifunctional protein GlmU	/	0.443
3fu8	3DM	Laccase-1	1.10.3.2	0.443
3hko	ANP	Calcium/calmodulin-dependent protein kinase with a kinase domain and 2 calmodulin-like EF hands	/	0.443
3hxd	BD7	Geranylgeranyl transferase type-2 subunit beta	2.5.1.60	0.443
3i8a	N22	Dihydrofolate reductase	1.5.1.3	0.443
3l08	ZIG	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.443
3lam	KRP	Gag-Pol polyprotein	2.7.7.49	0.443
3nnu	EDB	Mitogen-activated protein kinase 14	/	0.443
3qe2	FMN	NADPH--cytochrome P450 reductase	/	0.443
3rg9	WRA	Bifunctional dihydrofolate reductase-thymidylate synthase	1.5.1.3	0.443
3t8v	BTJ	M1 family aminopeptidase	3.4.11	0.443
3tnw	F18	Cyclin-dependent kinase 2	2.7.11.22	0.443
3vrv	YSD	Vitamin D3 receptor	/	0.443
4bfs	ZVS	Pantothenate kinase	2.7.1.33	0.443
4c57	FEF	Cyclin-G-associated kinase	2.7.11.1	0.443
4enh	FVX	Cholesterol 24-hydroxylase	/	0.443
4ez8	DHF	Thymidylate synthase	2.1.1.45	0.443
4g73	NAI	Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial	1.6.5.9	0.443
4hnc	0UT	Mandelate racemase	/	0.443
4neu	Q1A	Receptor-interacting serine/threonine-protein kinase 1	2.7.11.1	0.443
4qzu	RTL	Retinol-binding protein 2	/	0.443
5d7q	4I5	NAD-dependent protein deacetylase sirtuin-2	3.5.1	0.443
1daj	MOT	Dihydrofolate reductase	1.5.1.3	0.442
1ezf	IN0	Squalene synthase	2.5.1.21	0.442
1fby	REA	Retinoic acid receptor RXR-alpha	/	0.442
1gg5	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.442
1gii	1PU	Cyclin-dependent kinase 2	2.7.11.22	0.442
1i7g	AZ2	Peroxisome proliferator-activated receptor alpha	/	0.442
1nzf	UPG	DNA beta-glucosyltransferase	/	0.442
1qbg	FAD	NAD(P)H dehydrogenase [quinone] 1	1.6.5.2	0.442
1rt4	UC1	Gag-Pol polyprotein	2.7.7.49	0.442
1sbr	VIB	Putative HMP/thiamine-binding protein YkoF	/	0.442
1tka	N3T	Transketolase 1	2.2.1.1	0.442
2brb	PFQ	Serine/threonine-protein kinase Chk1	2.7.11.1	0.442
2c9d	PHR	6,7-dimethyl-8-ribityllumazine synthase	2.5.1.78	0.442
2hwr	DRD	Peroxisome proliferator-activated receptor gamma	/	0.442
2oiq	STI	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.442
2q9f	C3S	Cholesterol 24-hydroxylase	/	0.442
2qo9	ANP	Ephrin type-A receptor 3	2.7.10.1	0.442
2w1f	L0F	Aurora kinase A	2.7.11.1	0.442
2yxu	ATP	Pyridoxal kinase	2.7.1.35	0.442
2zb4	5OP	Prostaglandin reductase 2	1.3.1.48	0.442
3cqe	P91	Wee1-like protein kinase	2.7.10.2	0.442
3f69	XDR	Serine/threonine-protein kinase PknB	2.7.11.1	0.442
3fco	IIG	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.442
3gub	GUB	Death-associated protein kinase 1	2.7.11.1	0.442
3iok	1P6	Tyrosine-protein kinase JAK2	/	0.442
3l63	CAM	Camphor 5-monooxygenase	1.14.15.1	0.442
3q9x	EMO	Casein kinase II subunit alpha	2.7.11.1	0.442
3qaq	QAQ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.442
3qlr	QLR	Dihydrofolate reductase	1.5.1.3	0.442
3rmf	20Z	Cyclin-dependent kinase 2	2.7.11.22	0.442
3ttj	JBI	Mitogen-activated protein kinase 10	2.7.11.24	0.442
3w0j	T08	Vitamin D3 receptor	/	0.442
3w32	W32	Epidermal growth factor receptor	2.7.10.1	0.442
4azw	ATP	O-antigen chain terminator bifunctional methyltransferase/kinase WbdD	/	0.442
4elh	53I	Dihydrofolate reductase	/	0.442
4f9c	0SX	Cell division cycle 7-related protein kinase	2.7.11.1	0.442
4fuy	EK2	Mitogen-activated protein kinase 1	2.7.11.24	0.442
4h6p	FMN	Chromate reductase	/	0.442
4hfr	14M	Corticosteroid 11-beta-dehydrogenase isozyme 1	1.1.1.146	0.442
4ho4	THM	Glucose-1-phosphate thymidylyltransferase	/	0.442
4hy6	FJ1	Heat shock protein HSP 90-alpha	/	0.442
4i9i	1DY	Tankyrase-1	2.4.2.30	0.442
4j6d	TES	Cytochrome P450 monooxygenase	/	0.442
4jvf	17X	Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta	/	0.442
4oav	ACP	2-5A-dependent ribonuclease	3.1.26	0.442
4otp	ADP	Serine/threonine-protein kinase RIO1	2.7.11.1	0.442
4xwt	U5P	Ribonuclease J	/	0.442
5awm	ANP	Stress-activated protein kinase JNK	2.7.11.24	0.442
1a27	EST	Estradiol 17-beta-dehydrogenase 1	1.1.1.62	0.441
1f28	F89	Thymidylate synthase	2.1.1.45	0.441
1f4f	TP3	Thymidylate synthase	/	0.441
1v7a	FRC	Adenosine deaminase	3.5.4.4	0.441
1y4s	ADP	Chaperone protein HtpG	/	0.441
1yvj	4ST	Tyrosine-protein kinase JAK3	2.7.10.2	0.441
2bro	DF2	Serine/threonine-protein kinase Chk1	2.7.11.1	0.441
2bu9	HFV	Isopenicillin N synthase	1.21.3.1	0.441
2cch	ATP	Cyclin-dependent kinase 2	2.7.11.22	0.441
2hbh	XE4	Vitamin D3 receptor A	/	0.441
2hy8	1ST	Serine/threonine-protein kinase PAK 1	2.7.11.1	0.441
2oye	IM8	Prostaglandin G/H synthase 1	1.14.99.1	0.441
2qd3	CHD	Ferrochelatase, mitochondrial	4.99.1.1	0.441
2rkv	ZBA	Trichothecene 3-O-acetyltransferase	/	0.441
2uxp	CLM	HTH-type transcriptional regulator TtgR	/	0.441
2vag	V25	Dual specificity protein kinase CLK1	2.7.12.1	0.441
2wot	ZZG	TGF-beta receptor type-1	2.7.11.30	0.441
2ynf	WHU	Gag-Pol polyprotein	2.7.7.49	0.441
2zlc	VDX	Vitamin D3 receptor	/	0.441
3cd3	STU	Tyrosine-protein kinase Fes/Fps	2.7.10.2	0.441
3cgc	COA	Coenzyme A disulfide reductase	/	0.441
3cmf	PDN	3-oxo-5-beta-steroid 4-dehydrogenase	/	0.441
3ddp	RC8	Cyclin-dependent kinase 2	2.7.11.22	0.441
3ed1	GA3	Gibberellin receptor GID1	/	0.441
3hf6	LX0	Tryptophan 5-hydroxylase 1	1.14.16.4	0.441
3hmm	855	TGF-beta receptor type-1	2.7.11.30	0.441
3ia4	MTX	Dihydrofolate reductase	/	0.441
3k4s	0MO	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.441
3keu	ATP	Pyridoxal kinase	2.7.1.35	0.441
3nd1	SAH	Precorrin-6A synthase (Deacetylating)	/	0.441
3oez	STI	Proto-oncogene tyrosine-protein kinase Src	2.7.10.2	0.441
3pd3	A3T	Threonine--tRNA ligase	6.1.1.3	0.441
3ruh	NAD	UDP-N-acetylglucosamine 4-epimerase	/	0.441
3sgt	P09	Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)	/	0.441
3umw	596	Serine/threonine-protein kinase pim-1	2.7.11.1	0.441
3v9v	21L	Peroxisome proliferator-activated receptor gamma	/	0.441
3wiy	LC6	Induced myeloid leukemia cell differentiation protein Mcl-1	/	0.441
4a2j	AS0	Progesterone receptor	/	0.441
4acm	7YG	Cyclin-dependent kinase 2	2.7.11.22	0.441
4bii	PYW	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.441
4eev	L1X	Hepatocyte growth factor receptor	2.7.10.1	0.441
4eft	EFT	Heat shock protein HSP 90-alpha	/	0.441
4ful	0VU	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.441
4g1z	0VP	Vitamin D3 receptor A	/	0.441
4gdy	0X1	Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial	2.6.1.39	0.441
4gh6	LUO	High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A	/	0.441
4gk4	L90	Ephrin type-A receptor 3	2.7.10.1	0.441
4h50	NAP	Biphenyl dioxygenase ferredoxin reductase subunit	/	0.441
4iwv	1J9	Glucokinase	2.7.1.2	0.441
4q72	FAD	Bifunctional protein PutA	/	0.441
4qpm	ADP	Mitotic checkpoint serine/threonine-protein kinase BUB1	2.7.11.1	0.441
4z07	PCG	cGMP-dependent protein kinase 1	2.7.11.12	0.441
4zir	ANP	Energy-coupling factor transporter ATP-binding protein EcfA2	3.6.3	0.441
4zir	ANP	Energy-coupling factor transporter ATP-binding protein EcfA1	/	0.441
5cdt	PFB	Alcohol dehydrogenase E chain	1.1.1.1	0.441
1noo	CAH	Camphor 5-monooxygenase	1.14.15.1	0.440
1qcf	PP1	Tyrosine-protein kinase HCK	2.7.10.2	0.440
1rkx	NAD	CDP-D-glucose-4,6-dehydratase	/	0.440
1rt2	TNK	Gag-Pol polyprotein	2.7.7.49	0.440
1t9g	FAD	Medium-chain specific acyl-CoA dehydrogenase, mitochondrial	1.3.8.7	0.440
1uml	FR4	Adenosine deaminase	3.5.4.4	0.440
1uzw	CDH	Isopenicillin N synthase	1.21.3.1	0.440
1xds	DRA	Aclacinomycin 10-hydroxylase RdmB	4.1.1	0.440
1yhs	STU	Serine/threonine-protein kinase pim-1	2.7.11.1	0.440
1zp3	FAD	5,10-methylenetetrahydrofolate reductase	1.5.1.20	0.440
2brg	DFY	Serine/threonine-protein kinase Chk1	2.7.11.1	0.440
2cgx	3D3	Serine/threonine-protein kinase Chk1	2.7.11.1	0.440
2ea2	F77	Methionine aminopeptidase 2	/	0.440
2fon	FAD	Acyl-coenzyme A oxidase	/	0.440
2fyp	RDE	Endoplasmin	/	0.440
2pr2	DG1	Enoyl-[acyl-carrier-protein] reductase [NADH]	1.3.1.9	0.440
2qbm	CAM	Camphor 5-monooxygenase	1.14.15.1	0.440
2v4l	ABJ	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform	2.7.1.153	0.440
2y30	SM8	Putative repressor SimReg2	/	0.440
2z97	CAM	Camphor 5-monooxygenase	1.14.15.1	0.440
3bgz	VX3	Serine/threonine-protein kinase pim-1	2.7.11.1	0.440
3c6t	M14	Gag-Pol polyprotein	2.7.7.49	0.440
3drp	R8E	Gag-Pol polyprotein	2.7.7.49	0.440
3g4i	D71	cAMP-specific 3',5'-cyclic phosphodiesterase 4D	3.1.4.53	0.440
3i4b	Z48	Glycogen synthase kinase-3 beta	2.7.11.26	0.440
3lak	KR1	Gag-Pol polyprotein	2.7.7.49	0.440
3pd4	A3G	Threonine--tRNA ligase	6.1.1.3	0.440
3qpn	PFK	cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A	3.1.4.17	0.440
3rak	03Z	Cyclin-dependent kinase 2	2.7.11.22	0.440
3v94	WYQ	Phosphodiesterase	/	0.440
3vt4	5YI	Vitamin D3 receptor	/	0.440
3vt6	5YI	Vitamin D3 receptor	/	0.440
3zc6	VFC	Tyrosine-protein kinase JAK3	2.7.10.2	0.440
3zkp	ERB	Erythromycin C-12 hydroxylase	1.14.13.154	0.440
4an4	DUD	Putative glycosyl transferase	/	0.440
4bhw	01K	Histone acetyltransferase p300	/	0.440
4cd0	AWJ	ALK tyrosine kinase receptor	2.7.10.1	0.440
4e5n	NAD	Phosphonate dehydrogenase	1.20.1.1	0.440
4hvi	19S	Tyrosine-protein kinase JAK3	2.7.10.2	0.440
4iaq	2GM	5-hydroxytryptamine receptor 1B	/	0.440
4iui	1GQ	Estrogen receptor	/	0.440
4j7u	YTZ	Sepiapterin reductase	1.1.1.153	0.440
4jnk	ZHK	L-lactate dehydrogenase A chain	1.1.1.27	0.440
4l3j	5FI	Ribosomal protein S6 kinase beta-1	2.7.11.1	0.440
4nky	3QZ	Steroid 17-alpha-hydroxylase/17,20 lyase	/	0.440
4y8w	STR	Steroid 21-hydroxylase	/	0.440
4yau	FAD	NADPH--cytochrome P450 reductase	/	0.440
5d1b	TSN	Histone deacetylase 8	3.5.1.98	0.440
5iub	CLR	Adenosine receptor A2a	/	0.440