Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.770 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.763 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.755 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.747 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.742 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.736 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.733 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.731 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.721 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.716 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.709 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.708 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.691 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.672 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.657 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.656 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.649 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.646 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.643 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.641 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.639 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.634 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.630 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.629 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.628 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.625 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.621 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.619 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.617 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 3rz8 | RZ8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.590 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.587 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.586 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.583 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.571 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.567 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.565 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.562 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.558 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.549 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 1eou | SMS | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.547 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 4xiw | AZM | Carbonic anhydrase, alpha type | / | 0.541 | |
| 5fl4 | 9FK | Carbonic anhydrase 9 | 4.2.1.1 | 0.541 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.533 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.532 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.527 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.523 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.519 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.519 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.518 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.518 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.517 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.516 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.516 | |
| 1rj6 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.509 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.508 | |
| 4uwm | FMN | 3,6-diketocamphane 1,6 monooxygenase | 1.14.13 | 0.507 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.506 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.505 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.505 | |
| 2vbd | V10 | Isopenicillin N synthase | 1.21.3.1 | 0.498 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.497 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.493 | |
| 3zoi | M2W | Isopenicillin N synthase | 1.21.3.1 | 0.493 | |
| 4giu | 636 | Anthranilate phosphoribosyltransferase | / | 0.493 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.491 | |
| 1a5b | IGP | Tryptophan synthase alpha chain | / | 0.490 | |
| 1xva | SAM | Glycine N-methyltransferase | 2.1.1.20 | 0.490 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.489 | |
| 4ehy | ADP | Tetraacyldisaccharide 4'-kinase | / | 0.488 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.487 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.486 | |
| 2o1s | TDP | 1-deoxy-D-xylulose-5-phosphate synthase | 2.2.1.7 | 0.486 | |
| 4e2b | FMN | Dehydrogenase | / | 0.484 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.483 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.483 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.483 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.482 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.481 | |
| 1fmj | RTL | Retinol dehydratase | / | 0.481 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.481 | |
| 2wi7 | 2KL | Heat shock protein HSP 90-alpha | / | 0.480 | |
| 5ftf | ADP | TPR domain protein | / | 0.479 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.478 | |
| 2po7 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.478 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.478 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.478 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.477 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.477 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.476 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.476 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.476 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.475 | |
| 2zba | ZBA | Trichothecene 3-O-acetyltransferase | / | 0.475 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.475 | |
| 4r81 | FMN | Predicted NADH dehydrogenase | / | 0.475 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 3coy | 53H | Pantothenate synthetase | 6.3.2.1 | 0.474 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.474 | |
| 4f1l | 0RY | Poly [ADP-ribose] polymerase 14 | 2.4.2.30 | 0.474 | |
| 4o1m | NAD | Enoyl-acyl carrier reductase | / | 0.474 | |
| 4v12 | POG | MaoC like domain protein | / | 0.474 | |
| 2hve | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.473 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.473 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.472 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.472 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.472 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.472 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.472 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.471 | |
| 3qiz | QI2 | Botulinum neurotoxin type A | 3.4.24.69 | 0.471 | |
| 4dpu | AGS | Mevalonate diphosphate decarboxylase | / | 0.471 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.471 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.471 | |
| 3fhx | PXL | Pyridoxal kinase | 2.7.1.35 | 0.470 | |
| 4hmz | 18T | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.470 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.469 | |
| 1jtv | TES | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.469 | |
| 3bgx | MEF | Thymidylate synthase | / | 0.469 | |
| 3fp0 | FP0 | 15-O-acetyltransferase | / | 0.469 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.469 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.469 | |
| 3qe2 | FMN | NADPH--cytochrome P450 reductase | / | 0.469 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.469 | |
| 4usq | FAD | Pyridine nucleotide-disulfide oxidoreductase | / | 0.469 | |
| 1jdv | ADN | Purine nucleoside phosphorylase | / | 0.468 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.468 | |
| 1txt | CAA | HMG-CoA synthase | / | 0.468 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.468 | |
| 4gz6 | 12V | UDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit | / | 0.468 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.468 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.468 | |
| 1cqp | 803 | Integrin alpha-L | / | 0.467 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3gnc | QQQ | Glutaryl-CoA dehydrogenase | / | 0.467 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.467 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.467 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.467 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.466 | |
| 2yy2 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 5a01 | 12V | O-glycosyltransferase | / | 0.466 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.465 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.465 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.465 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 4egb | NAD | dTDP-glucose 4,6-dehydratase | / | 0.465 | |
| 1r6t | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.464 | |
| 2iko | 7IG | Renin | 3.4.23.15 | 0.464 | |
| 2jcx | NDP | 1-deoxy-D-xylulose 5-phosphate reductoisomerase | / | 0.464 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.464 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 4mr9 | 2BX | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.464 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.463 | |
| 1m8j | NAD | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.463 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.463 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.463 | |
| 4j75 | TYM | Tryptophan--tRNA ligase | / | 0.463 | |
| 1h85 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.462 | |
| 2q85 | 973 | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.462 | |
| 2xvq | 9DS | Serum albumin | / | 0.462 | |
| 3sl2 | ATP | Sensor histidine kinase WalK | / | 0.462 | |
| 4ho6 | UTP | Glucose-1-phosphate thymidylyltransferase | / | 0.462 | |
| 4q71 | FAD | Bifunctional protein PutA | / | 0.462 | |
| 4rls | NAI | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.462 | |
| 1b5e | DCM | Deoxycytidylate 5-hydroxymethyltransferase | 2.1.2.8 | 0.461 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.461 | |
| 2d1y | NAD | Oxidoreductase, short-chain dehydrogenase/reductase family | / | 0.461 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.461 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.461 | |
| 3fzf | ATP | Heat shock cognate 71 kDa protein | / | 0.461 | |
| 3hx4 | ANP | Calmodulin-domain protein kinase 1 | / | 0.461 | |
| 3vtd | TKD | Vitamin D3 receptor | / | 0.461 | |
| 4x7w | MVI | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.461 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.460 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.460 | |
| 1x1c | SAH | C-20 methyltransferase | / | 0.460 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.460 | |
| 2v59 | LZK | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 2w6p | OA4 | Biotin carboxylase | 6.3.4.14 | 0.460 | |
| 3ch6 | 311 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.460 | |
| 3sni | 546 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.460 | |
| 3v2u | ATP | Protein GAL3 | / | 0.460 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.459 | |
| 1qgy | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.459 | |
| 1sq5 | ADP | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 2ay9 | 5PV | Aromatic-amino-acid aminotransferase | 2.6.1.57 | 0.459 | |
| 2fw3 | BUI | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.459 | |
| 2il2 | LIX | Renin | 3.4.23.15 | 0.459 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.459 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.459 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.459 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.459 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.459 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.458 | |
| 1qpl | 587 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.458 | |
| 1x8l | OXR | Retinol dehydratase | / | 0.458 | |
| 2bfq | AR6 | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.458 | |
| 2bjf | DXC | Choloylglycine hydrolase | 3.5.1.24 | 0.458 | |
| 2rhr | EMO | Putative ketoacyl reductase | 1.3.1 | 0.458 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.458 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.458 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.458 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.458 | |
| 5c1m | CLR | Mu-type opioid receptor | / | 0.458 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.457 | |
| 2iib | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.457 | |
| 2j83 | BAT | Ulilysin | 3.4.24 | 0.457 | |
| 3ag6 | PAJ | Pantothenate synthetase | / | 0.457 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.457 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.457 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.457 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.457 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.457 | |
| 1ivs | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.456 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.456 | |
| 2bu9 | HFV | Isopenicillin N synthase | 1.21.3.1 | 0.456 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.456 | |
| 2yoj | 8Y6 | Genome polyprotein | 2.7.7.48 | 0.456 | |
| 3c21 | 2BA | DNA integrity scanning protein DisA | / | 0.456 | |
| 3ozc | 4CT | S-methyl-5'-thioadenosine phosphorylase | / | 0.456 | |
| 3w2e | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.456 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.456 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.456 | |
| 4x7u | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.456 | |
| 4s0v | SUV | Orexin receptor type 2 | / | 0.456 | |
| 1cg6 | MTA | S-methyl-5'-thioadenosine phosphorylase | / | 0.455 | |
| 1n77 | ATP | Glutamate--tRNA ligase | 6.1.1.17 | 0.455 | |
| 1nup | NMN | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.455 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.455 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.455 | |
| 1udb | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.455 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.455 | |
| 2d29 | FAD | Acyl-CoA dehydrogenase | / | 0.455 | |
| 2r8v | ACO | Amino-acid acetyltransferase | / | 0.455 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.455 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3lqf | NAD | Galactitol dehydrogenase | / | 0.455 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.455 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 4xz3 | COA | Acyl-CoA synthetase (NDP forming) | / | 0.455 | |
| 1cjk | FOK | Adenylate cyclase type 2 | / | 0.454 | |
| 1cjk | FOK | Adenylate cyclase type 5 | / | 0.454 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.454 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.454 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.454 | |
| 2c20 | NAD | UDP-glucose 4-epimerase | / | 0.454 | |
| 2i4q | UA4 | Renin | 3.4.23.15 | 0.454 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.454 | |
| 2v2z | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | / | 0.454 | |
| 3hcr | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.454 | |
| 3ieu | GDP | GTPase Era | / | 0.454 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.454 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.454 | |
| 3to3 | ATP | Petrobactin biosynthesis protein AsbB | / | 0.454 | |
| 3zv7 | NHG | Acetylcholinesterase | 3.1.1.7 | 0.454 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 4eb5 | PLP | Cysteine desulfurase IscS 2 | / | 0.454 | |
| 4g7g | VFV | Lanosterol 14-alpha-demethylase | / | 0.454 | |
| 4rvg | TYD | D-mycarose 3-C-methyltransferase | / | 0.454 | |
| 1bdm | NAX | Malate dehydrogenase | / | 0.453 | |
| 1g6o | ADP | Cag alpha | / | 0.453 | |
| 1gky | 5GP | Guanylate kinase | 2.7.4.8 | 0.453 | |
| 1i59 | ANP | Chemotaxis protein CheA | 2.7.13.3 | 0.453 | |
| 1ib0 | NAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.453 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.453 | |
| 1uxy | EPU | UDP-N-acetylenolpyruvoylglucosamine reductase | 1.3.1.98 | 0.453 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.453 | |
| 2ft9 | CHD | Fatty acid-binding protein 2, liver | / | 0.453 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.453 | |
| 2h55 | DZ8 | Heat shock protein HSP 90-alpha | / | 0.453 | |
| 2wyv | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH] | / | 0.453 | |
| 3a1c | ACP | Probable copper-exporting P-type ATPase A | 3.6.3.54 | 0.453 | |
| 4a84 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4hbg | NDP | 3-oxoacyl-[acyl-carrier-protein] reductase | 1.1.1.100 | 0.453 | |
| 4k6f | NAP | Putative Acetoacetyl-CoA reductase | / | 0.453 | |
| 4nes | UD1 | UDP-N-acetylglucosamine 2-epimerase | 5.1.3.14 | 0.453 | |
| 5cb3 | APR | O-acetyl-ADP-ribose deacetylase | / | 0.453 | |
| 1c3x | 8IG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.452 | |
| 1rft | PXM | Pyridoxal kinase | 2.7.1.35 | 0.452 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.452 | |
| 1yqd | NAP | Sinapyl alcohol dehydrogenase | / | 0.452 | |
| 2bfr | ADP | [Protein ADP-ribosylglutamate] hydrolase AF_1521 | 3.2.2 | 0.452 | |
| 3aw9 | GDU | NAD-dependent epimerase/dehydratase | / | 0.452 | |
| 3ruc | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.452 | |
| 3t4e | NAD | Quinate/shikimate dehydrogenase | / | 0.452 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.452 | |
| 4kfq | KFQ | Glutamate receptor ionotropic, NMDA 1 | / | 0.452 | |
| 4kky | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.452 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.452 | |
| 1n2h | PAJ | Pantothenate synthetase | 6.3.2.1 | 0.451 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.451 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.451 | |
| 2a92 | NAI | L-lactate dehydrogenase | / | 0.451 | |
| 2a94 | AP0 | L-lactate dehydrogenase | 1.1.1.27 | 0.451 | |
| 2i7p | ACO | Pantothenate kinase 3 | 2.7.1.33 | 0.451 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.451 | |
| 3aos | JH2 | Hemolymph juvenile hormone binding protein | / | 0.451 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.451 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.451 | |
| 1ex7 | 5GP | Guanylate kinase | 2.7.4.8 | 0.450 | |
| 1iol | EST | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.450 | |
| 1sd2 | MTH | S-methyl-5'-thioadenosine phosphorylase | / | 0.450 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 1zg3 | 2HI | Isoflavone 4'-O-methyltransferase | / | 0.450 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.450 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.450 | |
| 2ifa | FMN | Uncharacterized protein | / | 0.450 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.450 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.450 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.450 | |
| 2zcv | NDP | Quinone oxidoreductase 2 | 1.6.5.2 | 0.450 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.450 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.450 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.450 | |
| 3r95 | ACO | MccE protein | / | 0.450 | |
| 4b1i | A8P | Poly(ADP-ribose) glycohydrolase | 3.2.1.143 | 0.450 | |
| 4j49 | 1J1 | Uncharacterized protein | / | 0.450 | |
| 4kln | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.450 | |
| 4n82 | FMN | Ribonucleotide reductase (NrdI family protein), putative | / | 0.450 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.449 | |
| 1h74 | ADP | Homoserine kinase | 2.7.1.39 | 0.449 | |
| 1j37 | X8Z | Angiotensin-converting enzyme | 3.4.15.1 | 0.449 | |
| 1nuu | NAD | Nicotinamide/nicotinic acid mononucleotide adenylyltransferase 3 | / | 0.449 | |
| 2pob | GW4 | Peroxisome proliferator-activated receptor gamma | / | 0.449 | |
| 2x95 | X95 | Angiotensin-converting enzyme | 3.4.15.1 | 0.449 | |
| 3b9o | FMN | Alkane monoxygenase | / | 0.449 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.449 | |
| 3gwf | FAD | Cyclohexanone monooxygenase | / | 0.449 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.449 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.449 | |
| 4jf1 | PLP | Acetylornithine/succinyldiaminopimelate aminotransferase | 2.6.1.11 | 0.449 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.449 | |
| 4n4v | 2GY | Tankyrase-1 | 2.4.2.30 | 0.449 | |
| 1gax | VAA | Valine--tRNA ligase | 6.1.1.9 | 0.448 | |
| 1pl6 | 572 | Sorbitol dehydrogenase | 1.1.1.14 | 0.448 | |
| 1v45 | 3DG | Purine nucleoside phosphorylase | 2.4.2.1 | 0.448 | |
| 2a59 | LMZ | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.448 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.448 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.448 | |
| 2oeg | UPG | UDP-glucose pyrophosphorylase | / | 0.448 | |
| 2qd4 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.448 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.448 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.448 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.448 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.448 | |
| 3tyd | XHP | Dihydropteroate synthase | / | 0.448 | |
| 4b1r | ITC | Tetracycline repressor protein class D | / | 0.448 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.448 | |
| 4fgc | PQ0 | NADPH-dependent 7-cyano-7-deazaguanine reductase | 1.7.1.13 | 0.448 | |
| 4jbs | P52 | Endoplasmic reticulum aminopeptidase 2 | 3.4.11 | 0.448 | |
| 4r1f | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.448 | |
| 4rn6 | 15U | Prothrombin | 3.4.21.5 | 0.448 | |
| 4rp8 | ASC | Ascorbate-specific PTS system EIIC component | / | 0.448 | |
| 4yp6 | NAP | Nicotinamide-nucleotide adenylyltransferase | 2.7.7.1 | 0.448 | |
| 5kgh | ACO | Predicted acetyltransferase | / | 0.448 | |
| 1bdu | DUR | Thymidylate synthase | / | 0.447 | |
| 2fxv | 5GP | Xanthine phosphoribosyltransferase | 2.4.2.22 | 0.447 | |
| 2iku | LIY | Renin | 3.4.23.15 | 0.447 | |
| 2pnc | CLU | Primary amine oxidase, liver isozyme | / | 0.447 | |
| 2rh9 | IGP | Tryptophan synthase alpha chain | / | 0.447 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.447 | |
| 3ibq | ATP | Pyridoxal kinase | / | 0.447 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.447 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.447 | |
| 4amb | DUD | Putative glycosyl transferase | / | 0.447 | |
| 4brd | ANP | Ectonucleoside triphosphate diphosphohydrolase I | / | 0.447 | |
| 4eag | ATP | 5'-AMP-activated protein kinase subunit gamma-1 | / | 0.447 | |
| 4fhf | 0TT | Spore photoproduct lyase | / | 0.447 | |
| 4gv4 | MEJ | Poly [ADP-ribose] polymerase 3 | 2.4.2.30 | 0.447 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.447 | |
| 5irn | ADP | Nucleotide binding oligomerization domain containing 2 | / | 0.447 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.447 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1qrt | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.446 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.446 | |
| 1xh5 | R68 | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.446 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.446 | |
| 2c12 | FAD | Nitroalkane oxidase | 1.7.3.1 | 0.446 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.446 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.446 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.446 | |
| 2quj | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.446 | |
| 2y1o | T26 | UDP-N-acetylmuramoylalanine--D-glutamate ligase | 6.3.2.9 | 0.446 | |
| 2yj5 | ATP | Copper-transporting ATPase | / | 0.446 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.446 | |
| 3hl0 | NAD | Maleylacetate reductase | / | 0.446 | |
| 3p3c | 3P3 | UDP-3-O-acyl-N-acetylglucosamine deacetylase | / | 0.446 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.446 | |
| 3u5y | SCG | Raucaffricine-O-beta-D-glucosidase | 3.2.1.125 | 0.446 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.446 | |
| 4uym | VOR | 14-alpha sterol demethylase Cyp51B | / | 0.446 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.446 | |
| 4xgi | NAD | Glutamate dehydrogenase | / | 0.446 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.446 | |
| 1dr3 | HBI | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.445 | |
| 1qyx | ASD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.445 | |
| 2ex1 | C5P | Alpha-2,3/2,6-sialyltransferase/sialidase | / | 0.445 | |
| 2qd3 | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.445 | |
| 2rhg | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 2v58 | LZJ | Biotin carboxylase | 6.3.4.14 | 0.445 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.445 | |
| 3br3 | ET | HTH-type transcriptional regulator QacR | / | 0.445 | |
| 3ed1 | GA3 | Gibberellin receptor GID1 | / | 0.445 | |
| 3mau | EXT | Putative sphingosine-1-phosphate lyase | / | 0.445 | |
| 3mqg | ACO | Lipopolysaccharides biosynthesis acetyltransferase | / | 0.445 | |
| 3r7k | FDA | Probable acyl CoA dehydrogenase | / | 0.445 | |
| 3ruh | NAD | UDP-N-acetylglucosamine 4-epimerase | / | 0.445 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.445 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.445 | |
| 4dpi | 0N1 | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4h6p | FMN | Chromate reductase | / | 0.445 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.445 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.445 | |
| 5kwv | ANP | Pantothenate synthetase | / | 0.445 | |
| 1c7o | PPG | Hemolysin | / | 0.444 | |
| 1e3e | NAI | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.444 | |
| 1e64 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.444 | |
| 1r6u | TYM | Tryptophan--tRNA ligase, cytoplasmic | 6.1.1.2 | 0.444 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.444 | |
| 1rzu | ADP | Glycogen synthase 1 | 2.4.1.21 | 0.444 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.444 | |
| 1u0h | FOK | Adenylate cyclase type 2 | / | 0.444 | |
| 1u0h | FOK | Adenylate cyclase type 5 | / | 0.444 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.444 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.444 | |
| 2pau | D5M | 5'-deoxynucleotidase YfbR | / | 0.444 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3qpg | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.444 | |
| 4af7 | FAD | Ferredoxin--NADP reductase, leaf isozyme, chloroplastic | 1.18.1.2 | 0.444 | |
| 4cvm | ANP | UDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase | / | 0.444 | |
| 4eb7 | PLP | Cysteine desulfurase IscS 2 | / | 0.444 | |
| 4epl | JAI | Jasmonic acid-amido synthetase JAR1 | 6.3.2 | 0.444 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.444 | |
| 4h80 | 04T | Aldehyde dehydrogenase, dimeric NADP-preferring | / | 0.444 | |
| 4mk8 | 28Q | Genome polyprotein | 2.7.7.48 | 0.444 | |
| 4xwt | U5P | Ribonuclease J | / | 0.444 | |
| 5hg0 | SAM | Pantothenate synthetase | / | 0.444 | |
| 1fml | RTL | Retinol dehydratase | / | 0.443 | |
| 1qh0 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.443 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.443 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.443 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.443 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.443 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.443 | |
| 3csd | EMO | Putative ketoacyl reductase | 1.3.1 | 0.443 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.443 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3lnb | COA | N-acetyltransferase family protein | / | 0.443 | |
| 3mpj | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.443 | |
| 3oad | LPO | Renin | 3.4.23.15 | 0.443 | |
| 3ojx | FMN | NADPH--cytochrome P450 reductase | / | 0.443 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.443 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.443 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.443 | |
| 3zxi | TYA | Tyrosine--tRNA ligase, mitochondrial | 6.1.1.1 | 0.443 | |
| 4i1i | NAD | Malate dehydrogenase | / | 0.443 | |
| 4isg | 1FY | Glucokinase | 2.7.1.2 | 0.443 | |
| 4kto | FAD | Putative isovaleryl-CoA dehydrogenase protein | / | 0.443 | |
| 4wdb | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.443 | |
| 4x7v | MIV | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.443 | |
| 5eyu | NAD | Betaine-aldehyde dehydrogenase | / | 0.443 | |
| 5k2b | ZMA | Adenosine receptor A2a | / | 0.443 | |
| 1h73 | ANP | Homoserine kinase | 2.7.1.39 | 0.442 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.442 | |
| 1tsx | UMP | Thymidylate synthase | / | 0.442 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.442 | |
| 2fj1 | CTC | Tetracycline repressor protein class D | / | 0.442 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.442 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.442 | |
| 2ztl | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.442 | |
| 3f1k | NAP | Uncharacterized oxidoreductase YciK | 1 | 0.442 | |
| 3g70 | A5T | Renin | 3.4.23.15 | 0.442 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.442 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.442 | |
| 3qsa | TA7 | Anthranilate phosphoribosyltransferase | / | 0.442 | |
| 3vt8 | YI3 | Vitamin D3 receptor | / | 0.442 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.442 | |
| 4f3x | NAD | Putative aldehyde dehydrogenase | / | 0.442 | |
| 4f4d | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.442 | |
| 4hp8 | NAP | 2-deoxy-D-gluconate 3-dehydrogenase | / | 0.442 | |
| 4xbj | IN5 | Alanine racemase, biosynthetic | / | 0.442 | |
| 1beu | IPL | Tryptophan synthase alpha chain | / | 0.441 | |
| 1kvk | ATP | Mevalonate kinase | 2.7.1.36 | 0.441 | |
| 1m13 | HYF | Nuclear receptor subfamily 1 group I member 2 | / | 0.441 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.441 | |
| 1yrc | CAM | Camphor 5-monooxygenase | 1.14.15.1 | 0.441 | |
| 1zxn | ADP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.441 | |
| 2a0y | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.441 | |
| 2hk9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.441 | |
| 2ivn | ANP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.441 | |
| 2lba | CHO | Fatty acid binding protein 6 | / | 0.441 | |
| 3em0 | CHD | Fatty acid-binding protein 6, ileal (gastrotropin) | / | 0.441 | |
| 3gf4 | U5P | UDP-galactopyranose mutase | 5.4.99.9 | 0.441 | |
| 3h5s | H5S | Genome polyprotein | 2.7.7.48 | 0.441 | |
| 3sqx | ANP | ATP-dependent RNA helicase MSS116, mitochondrial | 3.6.4.13 | 0.441 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.441 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.441 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4g2j | 0WF | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.441 | |
| 4i13 | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 4imf | SI3 | N-acetylneuraminate lyase | / | 0.441 | |
| 4wec | NAD | Short chain dehydrogenase | / | 0.441 | |
| 5c77 | SAH | Protein arginine N-methyltransferase SFM1 | / | 0.441 | |
| 5std | UNN | Scytalone dehydratase | 4.2.1.94 | 0.441 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.440 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.440 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.440 | |
| 1qyw | 5SD | Estradiol 17-beta-dehydrogenase 1 | 1.1.1.62 | 0.440 | |
| 1tka | N3T | Transketolase 1 | 2.2.1.1 | 0.440 | |
| 1xe5 | 5FE | Plasmepsin-2 | 3.4.23.39 | 0.440 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.440 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 2acw | UPG | Glycosyltransferase | / | 0.440 | |
| 2ehu | NAD | 1-pyrroline-5-carboxylate dehydrogenase | / | 0.440 | |
| 2i65 | NAD | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.440 | |
| 2q66 | ATP | Poly(A) polymerase | 2.7.7.19 | 0.440 | |
| 3apw | DP0 | Alpha-1-acid glycoprotein 2 | / | 0.440 | |
| 3b2e | ADP | ATPase GET3 | / | 0.440 | |
| 3d4p | NAD | L-lactate dehydrogenase 1 | 1.1.1.27 | 0.440 | |
| 3d5m | 4MS | Genome polyprotein | 2.7.7.48 | 0.440 | |
| 3g72 | A6T | Renin | 3.4.23.15 | 0.440 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.440 | |
| 3gmd | 2M3 | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.440 | |
| 3oqf | S51 | Renin | 3.4.23.15 | 0.440 | |
| 3p3z | P3Z | Putative cytochrome P450 | / | 0.440 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3rgz | BLD | Protein BRASSINOSTEROID INSENSITIVE 1 | 2.7.10.1 | 0.440 | |
| 3tvq | DQH | Multifunctional cyclase-dehydratase-3-O-methyl transferase TcmN | 2.1.1 | 0.440 | |
| 4bge | PYW | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.440 | |
| 4c3f | 7KW | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.440 | |
| 4ey6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 4hn1 | TYD | dTDP-4-dehydro-6-deoxyglucose 3-epimerase | 5.1.3.27 | 0.440 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.440 | |
| 4jic | FMN | GTN Reductase | / | 0.440 | |
| 4v2g | ITC | Tetracycline repressor protein class D | / | 0.440 |