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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
3d8wD8WCarbonic anhydrase 24.2.1.1

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
3d8wD8WCarbonic anhydrase 24.2.1.11.000
1bn1AL5Carbonic anhydrase 24.2.1.10.770
1a42BZUCarbonic anhydrase 24.2.1.10.763
1bn4AL9Carbonic anhydrase 24.2.1.10.755
2h15B19Carbonic anhydrase 24.2.1.10.755
1bnnAL1Carbonic anhydrase 24.2.1.10.747
3k2fNKXCarbonic anhydrase 24.2.1.10.742
4mo82VQCarbonic anhydrase 24.2.1.10.736
3eft3BSCarbonic anhydrase 24.2.1.10.733
3v2jAZMCarbonic anhydrase 24.2.1.10.731
3d9zD9ZCarbonic anhydrase 24.2.1.10.721
1kwrSG2Carbonic anhydrase 24.2.1.10.716
3sbhE65Carbonic anhydrase 24.2.1.10.709
1bnuAL3Carbonic anhydrase 24.2.1.10.708
3dazMZMCarbonic anhydrase 24.2.1.10.708
4itoMPXCarbonic anhydrase 24.2.1.10.705
3dccD9ZCarbonic anhydrase 24.2.1.10.691
1g52F2BCarbonic anhydrase 24.2.1.10.685
1g1dFSBCarbonic anhydrase 24.2.1.10.684
3n4bWWZCarbonic anhydrase 24.2.1.10.684
3m5eJDRCarbonic anhydrase 24.2.1.10.682
3p5lIT5Carbonic anhydrase 24.2.1.10.675
3m2nJ74Carbonic anhydrase 24.2.1.10.673
1bnwTPDCarbonic anhydrase 24.2.1.10.672
4kap1QVCarbonic anhydrase 24.2.1.10.670
1if6FBUCarbonic anhydrase 24.2.1.10.669
3b4fTUOCarbonic anhydrase 24.2.1.10.669
3mhoJ43Carbonic anhydrase 24.2.1.10.669
4bf19FKCarbonic anhydrase 24.2.1.10.667
4bf6X0QCarbonic anhydrase 24.2.1.10.662
3dbuD8WCarbonic anhydrase 24.2.1.10.661
3mhlJ71Carbonic anhydrase 24.2.1.10.661
3qykIE2Carbonic anhydrase 24.2.1.10.659
4ilx1EZCarbonic anhydrase 24.2.1.10.659
1cnwEG1Carbonic anhydrase 24.2.1.10.657
3dc3AZMCarbonic anhydrase 24.2.1.10.656
1bntAL2Carbonic anhydrase 24.2.1.10.653
3mzcS6ICarbonic anhydrase 24.2.1.10.653
3oikWZBCarbonic anhydrase 24.2.1.10.653
1i91INQCarbonic anhydrase 24.2.1.10.649
1if7SBRCarbonic anhydrase 24.2.1.10.649
3mnaDWHCarbonic anhydrase 24.2.1.10.646
3oy0OY0Carbonic anhydrase 24.2.1.10.646
3oyqOYQCarbonic anhydrase 24.2.1.10.646
1cnyEG3Carbonic anhydrase 24.2.1.10.645
1if4FBSCarbonic anhydrase 24.2.1.10.645
1i9nIOACarbonic anhydrase 24.2.1.10.643
1xpz4TZCarbonic anhydrase 24.2.1.10.643
2eu3FF3Carbonic anhydrase 24.2.1.10.643
1cilETSCarbonic anhydrase 24.2.1.10.641
3ni5C1HCarbonic anhydrase 24.2.1.10.640
2wejFB2Carbonic anhydrase 24.2.1.10.639
1i8zINLCarbonic anhydrase 24.2.1.10.636
4iwz1GOCarbonic anhydrase 24.2.1.10.636
1zsbAZMCarbonic anhydrase 24.2.1.10.634
3ffpLC1Carbonic anhydrase 24.2.1.10.634
3dcwEZLCarbonic anhydrase 24.2.1.10.630
2wehFB1Carbonic anhydrase 24.2.1.10.629
3po6DT9Carbonic anhydrase 24.2.1.10.628
1g4jFFBCarbonic anhydrase 24.2.1.10.627
1cnxEG2Carbonic anhydrase 24.2.1.10.626
3mmfD9HCarbonic anhydrase 24.2.1.10.626
3n0nP9BCarbonic anhydrase 24.2.1.10.625
3oysOYSCarbonic anhydrase 24.2.1.10.625
3hkuTORCarbonic anhydrase 24.2.1.10.624
3bl1BL1Carbonic anhydrase 24.2.1.10.623
4itp1GDCarbonic anhydrase 24.2.1.10.623
3dd82C7Carbonic anhydrase 24.2.1.10.622
3l14I7BCarbonic anhydrase 24.2.1.10.622
1okmSABCarbonic anhydrase 24.2.1.10.621
4dz7D02Carbonic anhydrase 24.2.1.10.620
3ml2SU0Carbonic anhydrase 24.2.1.10.619
1ttm667Carbonic anhydrase 24.2.1.10.618
3dcsMZMCarbonic anhydrase 24.2.1.10.617
4kniE1ECarbonic anhydrase 24.2.1.10.615
1i90INMCarbonic anhydrase 24.2.1.10.613
4m2rBZ1Carbonic anhydrase 24.2.1.10.613
3mhcARZCarbonic anhydrase 24.2.1.10.612
1g4oBSBCarbonic anhydrase 24.2.1.10.611
1kwqSG1Carbonic anhydrase 24.2.1.10.611
4knjE1FCarbonic anhydrase 24.2.1.10.606
3t84SG6Carbonic anhydrase 24.2.1.10.605
3betCTFCarbonic anhydrase 24.2.1.10.604
4pxxCHDCarbonic anhydrase 24.2.1.10.604
2h4nAZMCarbonic anhydrase 24.2.1.10.597
2powI7CCarbonic anhydrase 24.2.1.10.597
3n3jWWVCarbonic anhydrase 24.2.1.10.596
3rz8RZ8Carbonic anhydrase 24.2.1.10.596
1if5FBTCarbonic anhydrase 24.2.1.10.595
4k0tD9ZCarbonic anhydrase 24.2.1.10.591
3mhiJ90Carbonic anhydrase 24.2.1.10.590
3oimVZ5Carbonic anhydrase 24.2.1.10.590
1bnmAL8Carbonic anhydrase 24.2.1.10.589
2weoFBWCarbonic anhydrase 24.2.1.10.589
3kigDA4Carbonic anhydrase 24.2.1.10.589
1bn3AL6Carbonic anhydrase 24.2.1.10.588
3m98E02Carbonic anhydrase 24.2.1.10.587
4n16CHDCarbonic anhydrase 24.2.1.10.587
1g45FSBCarbonic anhydrase 24.2.1.10.586
3f4xKLTCarbonic anhydrase 24.2.1.10.586
1oq5CELCarbonic anhydrase 24.2.1.10.583
2q1qOSPCarbonic anhydrase 24.2.1.10.583
3myqE27Carbonic anhydrase 24.2.1.10.579
5fltVJJCarbonic anhydrase 24.2.1.10.579
3t82SG4Carbonic anhydrase 24.2.1.10.578
2x7tWZBCarbonic anhydrase 24.2.1.10.576
3n2pAYXCarbonic anhydrase 24.2.1.10.576
3s8xE59Carbonic anhydrase 24.2.1.10.576
3m2yBE0Carbonic anhydrase 24.2.1.10.571
1oklMNSCarbonic anhydrase 24.2.1.10.569
1oknSTBCarbonic anhydrase 24.2.1.10.567
2wegFBVCarbonic anhydrase 24.2.1.10.567
3m67E36Carbonic anhydrase 24.2.1.10.565
1bnqAL4Carbonic anhydrase 24.2.1.10.562
3saxE50Carbonic anhydrase 24.2.1.10.562
1bnvAL7Carbonic anhydrase 24.2.1.10.558
3sbiE90Carbonic anhydrase 24.2.1.10.549
4kp8E1GCarbonic anhydrase 124.2.1.10.549
2wd2MS5Carbonic anhydrase 24.2.1.10.548
1eouSMSCarbonic anhydrase 24.2.1.10.547
3mdzEZLCarbonic anhydrase 74.2.1.10.547
1g54FFBCarbonic anhydrase 24.2.1.10.544
3igpDT7Carbonic anhydrase 24.2.1.10.544
3nb5R21Carbonic anhydrase 24.2.1.10.544
4xiwAZMCarbonic anhydrase, alpha type/0.541
5fl49FKCarbonic anhydrase 94.2.1.10.541
4k13ETSCarbonic anhydrase 24.2.1.10.540
4k0zMZMCarbonic anhydrase 24.2.1.10.533
1jd0AZMCarbonic anhydrase 124.2.1.10.532
3m96E38Carbonic anhydrase 24.2.1.10.532
2x7uWZACarbonic anhydrase 24.2.1.10.527
3t85SG7Carbonic anhydrase 24.2.1.10.527
3m40J45Carbonic anhydrase 24.2.1.10.524
3dd0EZLCarbonic anhydrase 24.2.1.10.523
1ydaAZMCarbonic anhydrase 24.2.1.10.520
4m2vBZ1Carbonic anhydrase 24.2.1.10.520
1i9pIOECarbonic anhydrase 24.2.1.10.519
4ht2V50Carbonic anhydrase 124.2.1.10.519
1xq04TRCarbonic anhydrase 24.2.1.10.518
2qimZEAClass 10 plant pathogenesis-related protein/0.518
3s9tE49Carbonic anhydrase 24.2.1.10.517
1i9qIOFCarbonic anhydrase 24.2.1.10.516
3rsv3RSBeta-secretase 13.4.23.460.516
1rj6AZMCarbonic anhydrase 144.2.1.10.509
4q0kGA3Phytohormone-binding protein/0.508
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.507
4kp5E1FCarbonic anhydrase 124.2.1.10.506
1hb1OCVIsopenicillin N synthase1.21.3.10.505
3f7uAG4Carbonic anhydrase 44.2.1.10.505
2vbdV10Isopenicillin N synthase1.21.3.10.498
4gh6LUOHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.497
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.493
3zoiM2WIsopenicillin N synthase1.21.3.10.493
4giu636Anthranilate phosphoribosyltransferase/0.493
1hb3SCVIsopenicillin N synthase1.21.3.10.491
1a5bIGPTryptophan synthase alpha chain/0.490
1xvaSAMGlycine N-methyltransferase2.1.1.200.490
2iviACWIsopenicillin N synthase1.21.3.10.489
2jb4A14Isopenicillin N synthase1.21.3.10.489
4ehyADPTetraacyldisaccharide 4'-kinase/0.488
4a83DXCMajor pollen allergen Bet v 1-A/0.487
1fm4DXCMajor pollen allergen Bet v 1-L/0.486
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.486
4e2bFMNDehydrogenase/0.484
1p0pBCHCholinesterase3.1.1.80.483
4bb3KKAIsopenicillin N synthase1.21.3.10.483
4mrm2BYGamma-aminobutyric acid type B receptor subunit 1/0.483
3jyqNADQuinate/shikimate dehydrogenase (NAD(+))/0.482
1bk0ACVIsopenicillin N synthase1.21.3.10.481
1fmjRTLRetinol dehydratase/0.481
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.481
2wi72KLHeat shock protein HSP 90-alpha/0.480
5ftfADPTPR domain protein/0.479
2g1n1IGRenin3.4.23.150.478
2po7CHDFerrochelatase, mitochondrial4.99.1.10.478
3dysIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.478
3zncBZ1Carbonic anhydrase 44.2.1.10.478
3p0fBAUUridine phosphorylase 22.4.2.30.477
4kbyC2EStimulator of interferon genes protein/0.477
2rlcCHDCholoylglycine hydrolase3.5.1.240.476
3w6hAZMCarbonic anhydrase 14.2.1.10.476
4bfvZVVPantothenate kinase2.7.1.330.476
2g1y5IGRenin3.4.23.150.475
2zbaZBATrichothecene 3-O-acetyltransferase/0.475
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.475
4r81FMNPredicted NADH dehydrogenase/0.475
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.474
3coy53HPantothenate synthetase6.3.2.10.474
3otbDGTProbable tRNA(His) guanylyltransferase2.7.7.790.474
4f1l0RYPoly [ADP-ribose] polymerase 142.4.2.300.474
4o1mNADEnoyl-acyl carrier reductase/0.474
4v12POGMaoC like domain protein/0.474
2hveADPNucleoside diphosphate kinase A2.7.4.60.473
4a862ANMajor pollen allergen Bet v 1-A/0.473
4dptAGSMevalonate diphosphate decarboxylase/0.473
2rqfJH3Hemolymph juvenile hormone binding protein/0.472
2xviFADPutative flavin-containing monooxygenase/0.472
3fw3ETSCarbonic anhydrase 44.2.1.10.472
4knmE1ECarbonic anhydrase 134.2.1.10.472
4lu3AZMCarbonic anhydrase 144.2.1.10.472
3otwCOAPhosphopantetheine adenylyltransferase/0.471
3qizQI2Botulinum neurotoxin type A3.4.24.690.471
4dpuAGSMevalonate diphosphate decarboxylase/0.471
4x5sAZMCarbonic anhydrase (Carbonate dehydratase)/0.471
5er0FADUncharacterized NAD(FAD)-dependent dehydrogenase/0.471
3fhxPXLPyridoxal kinase2.7.1.350.470
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.470
1if8SBSCarbonic anhydrase 24.2.1.10.469
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.469
3bgxMEFThymidylate synthase/0.469
3fp0FP015-O-acetyltransferase/0.469
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.469
3junAKDPhenazine biosynthesis protein A/B/0.469
3qe2FMNNADPH--cytochrome P450 reductase/0.469
3zkyWT4Isopenicillin N synthase1.21.3.10.469
4usqFADPyridine nucleotide-disulfide oxidoreductase/0.469
1jdvADNPurine nucleoside phosphorylase/0.468
1qiqACCIsopenicillin N synthase1.21.3.10.468
1txtCAAHMG-CoA synthase/0.468
3dyqIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.468
4p9dTMPDeoxycytidylate deaminase/0.468
4xoqF42Coenzyme F420:L-glutamate ligase/0.468
1cqp803Integrin alpha-L/0.467
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3gncQQQGlutaryl-CoA dehydrogenase/0.467
3gwfNAPCyclohexanone monooxygenase/0.467
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.467
3p8iFMNPentaerythritol tetranitrate reductase/0.467
4bfxZVXPantothenate kinase2.7.1.330.467
2cekN8TAcetylcholinesterase3.1.1.70.466
2yy2IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.466
5a0112VO-glycosyltransferase/0.466
1h50FMNPentaerythritol tetranitrate reductase/0.465
1uzwCDHIsopenicillin N synthase1.21.3.10.465
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.465
3qi4IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.465
4egbNADdTDP-glucose 4,6-dehydratase/0.465
1r6tTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.464
2iko7IGRenin3.4.23.150.464
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.464
2vn1FK5Peptidylprolyl isomerase/0.464
4kp61S1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.464
4mr92BXGamma-aminobutyric acid type B receptor subunit 1/0.464
1bwsNDPGDP-L-fucose synthase/0.463
1m8jNADNicotinamide-nucleotide adenylyltransferase2.7.7.10.463
1vi2NADQuinate/shikimate dehydrogenase/0.463
3c3xNAPEugenol synthase 11.1.1.3180.463
4j75TYMTryptophan--tRNA ligase/0.463
1h85FADFerredoxin--NADP reductase1.18.1.20.462
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.462
2xvq9DSSerum albumin/0.462
3sl2ATPSensor histidine kinase WalK/0.462
4ho6UTPGlucose-1-phosphate thymidylyltransferase/0.462
4q71FADBifunctional protein PutA/0.462
4rlsNAIL-lactate dehydrogenase A chain1.1.1.270.462
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.461
1x1aSAMC-20 methyltransferase/0.461
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.461
2f99AKVAklanonic acid methyl ester cyclase AcmA5.5.1.230.461
3dy8IBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3fzfATPHeat shock cognate 71 kDa protein/0.461
3hx4ANPCalmodulin-domain protein kinase 1/0.461
3vtdTKDVitamin D3 receptor/0.461
4x7wMVIMycinamicin III 3''-O-methyltransferase2.1.1.2370.461
1pqc444Oxysterols receptor LXR-beta/0.460
1qjfACSIsopenicillin N synthase1.21.3.10.460
1w06W05Isopenicillin N synthase1.21.3.10.460
1x1cSAHC-20 methyltransferase/0.460
2g247IGRenin3.4.23.150.460
2v59LZKBiotin carboxylase6.3.4.140.460
2w6pOA4Biotin carboxylase6.3.4.140.460
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.460
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3v2uATPProtein GAL3/0.460
3zbsOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.460
1blzACVIsopenicillin N synthase1.21.3.10.459
1qgyFADFerredoxin--NADP reductase1.18.1.20.459
1sq5ADPPantothenate kinase2.7.1.330.459
2ay95PVAromatic-amino-acid aminotransferase2.6.1.570.459
2fw3BUICarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.459
2il2LIXRenin3.4.23.150.459
2vouFAD2,6-dihydroxypyridine 3-monooxygenase1.14.13.100.459
3dyqPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.459
3tdaPN0Cytochrome P450 2D6/0.459
3w3lRX8Toll-like receptor 8/0.459
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.459
1kh3ANPArgininosuccinate synthase/0.458
1qpl587Peptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.458
1x8lOXRRetinol dehydratase/0.458
2bfqAR6[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.458
2bjfDXCCholoylglycine hydrolase3.5.1.240.458
2rhrEMOPutative ketoacyl reductase1.3.10.458
2vyqFADFerredoxin--NADP reductase1.18.1.20.458
2y60M8FIsopenicillin N synthase1.21.3.10.458
2y6fM9FIsopenicillin N synthase1.21.3.10.458
3f03FMNPentaerythritol tetranitrate reductase/0.458
4bfwZVWPantothenate kinase2.7.1.330.458
4e0u0MVCyclic dipeptide N-prenyltransferase/0.458
5c1mCLRMu-type opioid receptor/0.458
1w6hTITPlasmepsin-23.4.23.390.457
2iibC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.457
2j83BATUlilysin3.4.240.457
3ag6PAJPantothenate synthetase/0.457
3f7bAG5Carbonic anhydrase 44.2.1.10.457
3nl6TPSUncharacterized protein/0.457
3u9fCLMChloramphenicol acetyltransferase2.3.1.280.457
4a81DXCMajor pollen allergen Bet v 1-A/0.457
8catNDPCatalase1.11.1.60.457
1ivsVAAValine--tRNA ligase6.1.1.90.456
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.456
2bu9HFVIsopenicillin N synthase1.21.3.10.456
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
2yoj8Y6Genome polyprotein2.7.7.480.456
3c212BADNA integrity scanning protein DisA/0.456
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.456
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.456
4a802ANMajor pollen allergen Bet v 1-A/0.456
4mr72BVGamma-aminobutyric acid type B receptor subunit 1/0.456
4x7uZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.456
4s0vSUVOrexin receptor type 2/0.456
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.455
1n77ATPGlutamate--tRNA ligase6.1.1.170.455
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.455
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.455
1psa0ZLPepsin A3.4.23.10.455
1udbUFGUDP-glucose 4-epimerase5.1.3.20.455
2cy0NAPShikimate dehydrogenase (NADP(+))/0.455
2d29FADAcyl-CoA dehydrogenase/0.455
2r8vACOAmino-acid acetyltransferase/0.455
2wo7ASVIsopenicillin N synthase1.21.3.10.455
3k3ePDBHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.455
3lqfNADGalactitol dehydrogenase/0.455
3lxeTORCarbonic anhydrase 14.2.1.10.455
3p62FMNPentaerythritol tetranitrate reductase/0.455
4xz3COAAcyl-CoA synthetase (NDP forming)/0.455
1cjkFOKAdenylate cyclase type 2/0.454
1cjkFOKAdenylate cyclase type 5/0.454
1i9mINWCarbonic anhydrase 24.2.1.10.454
1obnASVIsopenicillin N synthase1.21.3.10.454
1w34FADFerredoxin--NADP reductase1.18.1.20.454
2c20NADUDP-glucose 4-epimerase/0.454
2i4qUA4Renin3.4.23.150.454
2uxoTACHTH-type transcriptional regulator TtgR/0.454
2v2zCDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase/0.454
3hcrCHDFerrochelatase, mitochondrial4.99.1.10.454
3ieuGDPGTPase Era/0.454
3jsxCC2NAD(P)H dehydrogenase [quinone] 11.6.5.20.454
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.454
3to3ATPPetrobactin biosynthesis protein AsbB/0.454
3zv7NHGAcetylcholinesterase3.1.1.70.454
4bfzZVZPantothenate kinase2.7.1.330.454
4eb5PLPCysteine desulfurase IscS 2/0.454
4g7gVFVLanosterol 14-alpha-demethylase/0.454
4rvgTYDD-mycarose 3-C-methyltransferase/0.454
1bdmNAXMalate dehydrogenase/0.453
1g6oADPCag alpha/0.453
1gky5GPGuanylate kinase2.7.4.80.453
1i59ANPChemotaxis protein CheA2.7.13.30.453
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.453
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
1uxyEPUUDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.453
2ea2F77Methionine aminopeptidase 2/0.453
2ft9CHDFatty acid-binding protein 2, liver/0.453
2g1r3IGRenin3.4.23.150.453
2h55DZ8Heat shock protein HSP 90-alpha/0.453
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.453
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.453
4a84DXCMajor pollen allergen Bet v 1-A/0.453
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.453
4k6fNAPPutative Acetoacetyl-CoA reductase/0.453
4nesUD1UDP-N-acetylglucosamine 2-epimerase5.1.3.140.453
5cb3APRO-acetyl-ADP-ribose deacetylase/0.453
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.452
1rftPXMPyridoxal kinase2.7.1.350.452
1udaUFGUDP-glucose 4-epimerase5.1.3.20.452
1yqdNAPSinapyl alcohol dehydrogenase/0.452
2bfrADP[Protein ADP-ribosylglutamate] hydrolase AF_15213.2.20.452
3aw9GDUNAD-dependent epimerase/dehydratase/0.452
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.452
3t4eNADQuinate/shikimate dehydrogenase/0.452
3tjzGNPADP-ribosylation factor 1/0.452
4kfqKFQGlutamate receptor ionotropic, NMDA 1/0.452
4kkyCAMCamphor 5-monooxygenase1.14.15.10.452
4x7zZM3Mycinamicin III 3''-O-methyltransferase2.1.1.2370.452
1n2hPAJPantothenate synthetase6.3.2.10.451
1sojIBMcGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.451
1x27ASP_ASP_TYR_VAL_PTRTyrosine-protein kinase Lck2.7.10.20.451
2a92NAIL-lactate dehydrogenase/0.451
2a94AP0L-lactate dehydrogenase1.1.1.270.451
2i7pACOPantothenate kinase 32.7.1.330.451
2q7oIMHPurine nucleoside phosphorylase2.4.2.10.451
3aosJH2Hemolymph juvenile hormone binding protein/0.451
4q72FADBifunctional protein PutA/0.451
5iw5NMNNADH pyrophosphatase/0.451
1ex75GPGuanylate kinase2.7.4.80.450
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.450
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
1zg32HIIsoflavone 4'-O-methyltransferase/0.450
1zklIBMHigh affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A3.1.4.530.450
2e99B08Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.450
2ifaFMNUncharacterized protein/0.450
2igoFADPyranose 2-oxidase/0.450
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.450
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.450
2zcvNDPQuinone oxidoreductase 21.6.5.20.450
3fapARDPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.450
3fapARDSerine/threonine-protein kinase mTOR2.7.11.10.450
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
3r95ACOMccE protein/0.450
4b1iA8PPoly(ADP-ribose) glycohydrolase3.2.1.1430.450
4j491J1Uncharacterized protein/0.450
4klnAGSTransitional endoplasmic reticulum ATPase3.6.4.60.450
4n82FMNRibonucleotide reductase (NrdI family protein), putative/0.450
1h63FMNPentaerythritol tetranitrate reductase/0.449
1h74ADPHomoserine kinase2.7.1.390.449
1j37X8ZAngiotensin-converting enzyme3.4.15.10.449
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.449
2pobGW4Peroxisome proliferator-activated receptor gamma/0.449
2x95X95Angiotensin-converting enzyme3.4.15.10.449
3b9oFMNAlkane monoxygenase/0.449
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.449
3gwfFADCyclohexanone monooxygenase/0.449
3k8q22APurine nucleoside phosphorylase2.4.2.10.449
3ziuLSSLeucyl-tRNA synthetase/0.449
4jf1PLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.449
4m83ERYOleandomycin glycosyltransferase2.4.10.449
4n4v2GYTankyrase-12.4.2.300.449
1gaxVAAValine--tRNA ligase6.1.1.90.448
1pl6572Sorbitol dehydrogenase1.1.1.140.448
1v453DGPurine nucleoside phosphorylase2.4.2.10.448
2a59LMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.448
2b58COADiamine acetyltransferase 1/0.448
2g263LGRenin3.4.23.150.448
2oegUPGUDP-glucose pyrophosphorylase/0.448
2qd4CHDFerrochelatase, mitochondrial4.99.1.10.448
2r0cFADPutative FAD-monooxygenase/0.448
3aezGDPPantothenate kinase2.7.1.330.448
3cmfPDN3-oxo-5-beta-steroid 4-dehydrogenase/0.448
3h3qH13Collagen type IV alpha-3-binding protein/0.448
3tydXHPDihydropteroate synthase/0.448
4b1rITCTetracycline repressor protein class D/0.448
4b4vL34Bifunctional protein FolD/0.448
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.448
4jbsP52Endoplasmic reticulum aminopeptidase 23.4.110.448
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.448
4rn615UProthrombin3.4.21.50.448
4rp8ASCAscorbate-specific PTS system EIIC component/0.448
4yp6NAPNicotinamide-nucleotide adenylyltransferase2.7.7.10.448
5kghACOPredicted acetyltransferase/0.448
1bduDURThymidylate synthase/0.447
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.447
2ikuLIYRenin3.4.23.150.447
2pncCLUPrimary amine oxidase, liver isozyme/0.447
2rh9IGPTryptophan synthase alpha chain/0.447
3dylPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3fr5I4AFatty acid-binding protein, adipocyte/0.447
3ibqATPPyridoxal kinase/0.447
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3qeoLLTDeoxycytidine kinase2.7.1.740.447
3uayADNPurine nucleoside phosphorylase DeoD-type/0.447
4ambDUDPutative glycosyl transferase/0.447
4brdANPEctonucleoside triphosphate diphosphohydrolase I/0.447
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.447
4fhf0TTSpore photoproduct lyase/0.447
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.447
4h9tHL4Phosphotriesterase/0.447
5irnADPNucleotide binding oligomerization domain containing 2/0.447
4zj8SUVOrexin receptor type 1/0.447
1oc1ASVIsopenicillin N synthase1.21.3.10.446
1qrtATPGlutamine--tRNA ligase6.1.1.180.446
1x1bSAHC-20 methyltransferase/0.446
1xh5R68cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.446
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.446
2c12FADNitroalkane oxidase1.7.3.10.446
2g226IGRenin3.4.23.150.446
2gv8NDPThiol-specific monooxygenase1.14.130.446
2iyfERYOleandomycin glycosyltransferase2.4.10.446
2qujTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.446
2y1oT26UDP-N-acetylmuramoylalanine--D-glutamate ligase6.3.2.90.446
2yj5ATPCopper-transporting ATPase/0.446
3fhxPLPPyridoxal kinase2.7.1.350.446
3hl0NADMaleylacetate reductase/0.446
3p3c3P3UDP-3-O-acyl-N-acetylglucosamine deacetylase/0.446
3phiNDPShikimate dehydrogenase (NADP(+))/0.446
3u5ySCGRaucaffricine-O-beta-D-glucosidase3.2.1.1250.446
3wv9FEGHmd co-occurring protein HcgE/0.446
4uymVOR14-alpha sterol demethylase Cyp51B/0.446
4wda2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.446
4xgiNADGlutamate dehydrogenase/0.446
5hbrCOAAcyl-CoA synthetase (NDP forming)/0.446
1dr3HBIDihydrofolate reductase1.5.1.30.445
1o9bNAIQuinate/shikimate dehydrogenase/0.445
1qyxASDEstradiol 17-beta-dehydrogenase 11.1.1.620.445
2ex1C5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.445
2qd3CHDFerrochelatase, mitochondrial4.99.1.10.445
2rhgIGPTryptophan synthase alpha chain/0.445
2v58LZJBiotin carboxylase6.3.4.140.445
2yozOVE2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.445
3br3ETHTH-type transcriptional regulator QacR/0.445
3ed1GA3Gibberellin receptor GID1/0.445
3mauEXTPutative sphingosine-1-phosphate lyase/0.445
3mqgACOLipopolysaccharides biosynthesis acetyltransferase/0.445
3r7kFDAProbable acyl CoA dehydrogenase/0.445
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.445
3vydVYDRenin3.4.23.150.445
4dbzNDPPutative ketoacyl reductase1.3.10.445
4dpi0N1Beta-secretase 13.4.23.460.445
4h6pFMNChromate reductase/0.445
4psbGA3Cytokinin-specific binding protein/0.445
4uovAZMCarbonate dehydratase/0.445
5kwvANPPantothenate synthetase/0.445
1c7oPPGHemolysin/0.444
1e3eNAIAlcohol dehydrogenase 41.1.1.10.444
1e64FADFerredoxin--NADP reductase1.18.1.20.444
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.444
1rszDIHPurine nucleoside phosphorylase2.4.2.10.444
1rzuADPGlycogen synthase 12.4.1.210.444
1t7o152Carnitine O-acetyltransferase2.3.1.70.444
1u0hFOKAdenylate cyclase type 2/0.444
1u0hFOKAdenylate cyclase type 5/0.444
2dvlFADAcyl-CoA dehydrogenase/0.444
2g1s4IGRenin3.4.23.150.444
2pauD5M5'-deoxynucleotidase YfbR/0.444
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.444
3qpg3QPAspartate aminotransferase2.6.1.10.444
4af7FADFerredoxin--NADP reductase, leaf isozyme, chloroplastic1.18.1.20.444
4cvmANPUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.444
4eb7PLPCysteine desulfurase IscS 2/0.444
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.444
4fcd0T6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4h8004TAldehyde dehydrogenase, dimeric NADP-preferring/0.444
4mk828QGenome polyprotein2.7.7.480.444
4xwtU5PRibonuclease J/0.444
5hg0SAMPantothenate synthetase/0.444
1fmlRTLRetinol dehydratase/0.443
1qh0FADFerredoxin--NADP reductase1.18.1.20.443
1xe65FPPlasmepsin-23.4.23.390.443
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.443
2fm0M98cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
2g1o2IGRenin3.4.23.150.443
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.443
3csdEMOPutative ketoacyl reductase1.3.10.443
3dzkNMNADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.443
3h3t16HCollagen type IV alpha-3-binding protein/0.443
3lnbCOAN-acetyltransferase family protein/0.443
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.443
3oadLPORenin3.4.23.150.443
3ojxFMNNADPH--cytochrome P450 reductase/0.443
3qj0QI3Botulinum neurotoxin type A3.4.24.690.443
3rbaCODPhosphopantetheine adenylyltransferase/0.443
3vswR31Renin3.4.23.150.443
3zxiTYATyrosine--tRNA ligase, mitochondrial6.1.1.10.443
4i1iNADMalate dehydrogenase/0.443
4isg1FYGlucokinase2.7.1.20.443
4ktoFADPutative isovaleryl-CoA dehydrogenase protein/0.443
4wdb2AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.443
4x7vMIVMycinamicin III 3''-O-methyltransferase2.1.1.2370.443
5eyuNADBetaine-aldehyde dehydrogenase/0.443
5k2bZMAAdenosine receptor A2a/0.443
1h73ANPHomoserine kinase2.7.1.390.442
1icpFMN12-oxophytodienoate reductase 11.3.1.420.442
1tsxUMPThymidylate synthase/0.442
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.442
2fj1CTCTetracycline repressor protein class D/0.442
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.442
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.442
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.442
3f1kNAPUncharacterized oxidoreductase YciK10.442
3g70A5TRenin3.4.23.150.442
3h3sH15Collagen type IV alpha-3-binding protein/0.442
3pl8FADPyranose 2-oxidase/0.442
3qsaTA7Anthranilate phosphoribosyltransferase/0.442
3vt8YI3Vitamin D3 receptor/0.442
4a6rTA8Probable aminotransferase/0.442
4f3xNADPutative aldehyde dehydrogenase/0.442
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.442
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.442
4xbjIN5Alanine racemase, biosynthetic/0.442
1beuIPLTryptophan synthase alpha chain/0.441
1kvkATPMevalonate kinase2.7.1.360.441
1m13HYFNuclear receptor subfamily 1 group I member 2/0.441
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.441
1yrcCAMCamphor 5-monooxygenase1.14.15.10.441
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.441
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.441
2hk9NAPShikimate dehydrogenase (NADP(+))/0.441
2ivnANPtRNA N6-adenosine threonylcarbamoyltransferase/0.441
2lbaCHOFatty acid binding protein 6/0.441
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.441
3gf4U5PUDP-galactopyranose mutase5.4.99.90.441
3h5sH5SGenome polyprotein2.7.7.480.441
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.441
4a87NARMajor pollen allergen Bet v 1-A/0.441
4c3yFAD3-ketosteroid dehydrogenase/0.441
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.441
4g2j0WFHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
4i13FOLDihydrofolate reductase1.5.1.30.441
4imfSI3N-acetylneuraminate lyase/0.441
4wecNADShort chain dehydrogenase/0.441
5c77SAHProtein arginine N-methyltransferase SFM1/0.441
5stdUNNScytalone dehydratase4.2.1.940.441
1cf3FADGlucose oxidase1.1.3.40.440
1oj4CDM4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.440
1qoqIGPTryptophan synthase alpha chain/0.440
1qyw5SDEstradiol 17-beta-dehydrogenase 11.1.1.620.440
1tkaN3TTransketolase 12.2.1.10.440
1xe55FEPlasmepsin-23.4.23.390.440
1yw8A75Methionine aminopeptidase 2/0.440
2abbFMNPentaerythritol tetranitrate reductase/0.440
2acwUPGGlycosyltransferase/0.440
2ehuNAD1-pyrroline-5-carboxylate dehydrogenase/0.440
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.440
2q66ATPPoly(A) polymerase2.7.7.190.440
3apwDP0Alpha-1-acid glycoprotein 2/0.440
3b2eADPATPase GET3/0.440
3d4pNADL-lactate dehydrogenase 11.1.1.270.440
3d5m4MSGenome polyprotein2.7.7.480.440
3g72A6TRenin3.4.23.150.440
3gfbNADL-threonine 3-dehydrogenase/0.440
3gmd2M3Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3oqfS51Renin3.4.23.150.440
3p3zP3ZPutative cytochrome P450/0.440
3p67FMNPentaerythritol tetranitrate reductase/0.440
3rgzBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
3tvqDQHMultifunctional cyclase-dehydratase-3-O-methyl transferase TcmN2.1.10.440
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.440
4ey6GNTAcetylcholinesterase3.1.1.70.440
4hn1TYDdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.440
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.440
4jicFMNGTN Reductase/0.440
4v2gITCTetracycline repressor protein class D/0.440