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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1l4hNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity
Align
1l4hNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.211.000
1l4lNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.809
1l4mNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.740
1l4kNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.720
1l4gNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.661
1jhrP2PNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.640
1l4fNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.609
1d0vRBZNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.607
1jhoRMBNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.600
1l4eRBZNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.571
1l5l7RPNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.562
1l5m7RANicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.546
1jhaAAMNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.537
1l5oNCNNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.523
1l5k1RBNicotinate-nucleotide--dimethylbenzimidazole phosphoribosyltransferase2.4.2.210.519
1culFOKAdenylate cyclase type 2/0.508
1culFOKAdenylate cyclase type 5/0.508
3ajrNADNDP-sugar epimerase/0.499
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.498
4i8zG08Gag-Pol polyprotein3.4.23.160.496
3i59N6RCRP-like cAMP-activated global transcriptional regulator/0.494
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.488
2znq401Peroxisome proliferator-activated receptor delta/0.487
3nd1SAHPrecorrin-6A synthase (Deacetylating)/0.487
4gh5NADShort-chain dehydrogenase/reductase SDR/0.487
4iwq1FVSerine/threonine-protein kinase TBK12.7.11.10.485
1xl5190Gag-Pol polyprotein3.4.23.160.484
1rw8580TGF-beta receptor type-12.7.11.300.483
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.482
4xb2NDP319aa long hypothetical homoserine dehydrogenase/0.481
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.480
4ktc1X3Genome polyprotein3.4.21.980.480
4q71FADBifunctional protein PutA/0.480
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.479
3qwfNAP17beta-hydroxysteroid dehydrogenase/0.479
1gqtACPRibokinase/0.477
2ft9CHDFatty acid-binding protein 2, liver/0.477
3cblSTUTyrosine-protein kinase Fes/Fps2.7.10.20.477
3zewSTUEphrin type-B receptor 42.7.10.10.477
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.477
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.476
2ed5SAHDiphthine synthase/0.476
3s4qNK0Mitogen-activated protein kinase 14/0.476
1cjkFOKAdenylate cyclase type 2/0.475
1cjkFOKAdenylate cyclase type 5/0.475
1cjtFOKAdenylate cyclase type 2/0.475
1cjtFOKAdenylate cyclase type 5/0.475
1ep3FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.474
1msmJE2Gag-Pol polyprotein3.4.23.160.474
2p3b3TLV-1 PROTEASE protein/0.474
2p3b3TLV-1 protease/0.474
4jxrACOAcetyltransferase/0.474
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.474
2dv4SAHDiphthine synthase/0.473
3a1nNADNDP-sugar epimerase/0.473
3fwjCAMCamphor 5-monooxygenase1.14.15.10.473
4a30QMIGlycylpeptide N-tetradecanoyltransferase/0.473
4dbzNDPPutative ketoacyl reductase1.3.10.473
1dxoFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.472
1gcoNADGlucose 1-dehydrogenase1.1.1.470.472
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.472
2a1oCAMCamphor 5-monooxygenase1.14.15.10.471
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.471
2jcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.471
3gobHXXDdmC/0.471
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.469
1hbvGANGag-Pol polyprotein/0.469
2iyfERYOleandomycin glycosyltransferase2.4.10.469
2p5uNADUDP-glucose 4-epimerase/0.469
3bbrBHYGlutamate receptor 2/0.469
3n4kSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.469
3p19NDPPutative blue fluorescent protein/0.469
3zh8C58Protein kinase C iota type2.7.11.130.469
4e5yNDPGDP-L-fucose synthase1.1.1.2710.469
4ji91M3Tyrosine-protein kinase JAK2/0.469
1bwaXV6Gag-Pol polyprotein3.4.23.160.468
1ia4TQ6Dihydrofolate reductase1.5.1.30.468
2xckMH43-phosphoinositide-dependent protein kinase 12.7.11.10.468
4dc0NDPPutative ketoacyl reductase1.3.10.468
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.468
1drhNAPDihydrofolate reductase1.5.1.30.467
2emrSAHDiphthine synthase/0.467
2p20PRXAcetyl-coenzyme A synthetase/0.467
2p2mPRXAcetyl-coenzyme A synthetase/0.467
3autNAIGlucose 1-dehydrogenase 41.1.1.470.467
3fp0FP015-O-acetyltransferase/0.467
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.467
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.466
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.466
3qlrNDPDihydrofolate reductase1.5.1.30.466
3zc5W9ZHepatocyte growth factor receptor2.7.10.10.466
4fv7E94Mitogen-activated protein kinase 12.7.11.240.466
4h3ySAHtRNA (guanine-N(1)-)-methyltransferase/0.466
5dp2NAPCurF/0.466
1bk0ACVIsopenicillin N synthase1.21.3.10.465
1geeNADGlucose 1-dehydrogenase1.1.1.470.465
2avvMK1Gag-Pol polyprotein3.4.23.160.465
3d8vUD1Bifunctional protein GlmU/0.465
3pwm017Gag-Pol polyprotein3.4.23.160.465
4du82P0Mevalonate diphosphate decarboxylase/0.465
4uymVOR14-alpha sterol demethylase Cyp51B/0.465
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.464
1kbqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.464
1ywgNADGlyceraldehyde-3-phosphate dehydrogenase/0.464
2b60RITPol polyprotein/0.464
2dxwSAHDiphthine synthase/0.464
2e17SAHDiphthine synthase/0.464
2eq6FADDihydrolipoyl dehydrogenase/0.464
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.464
3lzs017Gag-Pol polyprotein3.4.23.160.464
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.464
1dr3TAPDihydrofolate reductase1.5.1.30.463
1ia3TQ5Dihydrofolate reductase1.5.1.30.463
2bxmIMNSerum albumin/0.463
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.463
2iviACWIsopenicillin N synthase1.21.3.10.463
2ntrL00Beta-secretase 13.4.23.460.463
3a3yOBNSodium/potassium-transporting ATPase subunit alpha/0.463
4bwxAGSPAB-dependent poly(A)-specific ribonuclease subunit pan3/0.463
4jwhSAHtRNA (guanine(9)-N1)-methyltransferase/0.463
4uyf73BBromodomain-containing protein 2/0.463
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.462
1hfqMOTDihydrofolate reductase1.5.1.30.462
2ccu2D9Heat shock protein HSP 90-alpha/0.462
2owkSAHDiphthine synthase/0.462
2vwqNAPGlucose 1-dehydrogenase/0.462
2xx91NFGlutamate receptor 2/0.462
3ndcSAHPrecorrin-4 C(11)-methyltransferase2.1.1.1330.462
3upf0BUPolyprotein/0.462
5d3qGDPDynamin-13.6.5.50.462
1beuIPLTryptophan synthase alpha chain/0.461
1dirNADDihydropteridine reductase1.5.1.340.461
1eh4IC1Casein kinase I homolog 12.7.11.10.461
1kzjCB3Thymidylate synthase/0.461
1wngSAHDiphthine synthase/0.461
3a1cACPProbable copper-exporting P-type ATPase A3.6.3.540.461
3a3bRBFLumazine protein/0.461
3gqvNAPEnoyl reductase LovC10.461
4o1mNADEnoyl-acyl carrier reductase/0.461
1rfvADPPyridoxal kinase2.7.1.350.460
2vwx7X4Ephrin type-B receptor 42.7.10.10.460
2yy8SAMtRNA (cytidine(56)-2'-O)-methyltransferase/0.460
4fmxCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.460
4y95746Tyrosine-protein kinase/0.460
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.459
1hsgMK1Gag-Pol polyprotein/0.459
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
1rm5NDPGlyceraldehyde-3-phosphate dehydrogenase A, chloroplastic1.2.1.130.459
1w4zNAPPutative ketoacyl reductase1.3.10.459
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.459
2r6gATPMaltose/maltodextrin import ATP-binding protein MalK/0.459
4m6jNDPDihydrofolate reductase1.5.1.30.459
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.459
5dn3ATPAurora kinase A2.7.11.10.459
1meiMOAInosine-5'-monophosphate dehydrogenase/0.458
2favAPRNonstructural polyprotein pp1a/0.458
2vcj2EQHeat shock protein HSP 90-alpha/0.458
3oeyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.458
3tog079Gag-Pol polyprotein2.7.7.490.458
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.458
4j7xNAPSepiapterin reductase1.1.1.1530.458
4m83ERYOleandomycin glycosyltransferase2.4.10.458
1hb3SCVIsopenicillin N synthase1.21.3.10.457
1llqNADNAD-dependent malic enzyme, mitochondrial1.1.1.380.457
1me7MOAInosine-5'-monophosphate dehydrogenase/0.457
2abbFMNPentaerythritol tetranitrate reductase/0.457
2p2qPRXAcetyl-coenzyme A synthetase/0.457
2ztlNADD(-)-3-hydroxybutyrate dehydrogenase/0.457
3bvb017Gag-Pol polyprotein3.4.23.160.457
3iocA5DPantothenate synthetase6.3.2.10.457
3upkUD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.457
4mcb21WtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.457
1bdlIM1Gag-Pol polyprotein3.4.23.160.456
1cs4FOKAdenylate cyclase type 2/0.456
1cs4FOKAdenylate cyclase type 5/0.456
1dbvNADGlyceraldehyde-3-phosphate dehydrogenase/0.456
1qorNDPQuinone oxidoreductase 1/0.456
1u3dFADCryptochrome-1/0.456
1xddAAYIntegrin alpha-L/0.456
2e08SAHDiphthine synthase/0.456
2f81017Gag-Pol polyprotein3.4.23.160.456
2nniMTKCytochrome P450 2C8/0.456
2o12FMNChorismate synthase/0.456
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.456
2xvw9NRSerum albumin/0.456
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.456
3cic316Beta-secretase 13.4.23.460.456
3h6vNS6Glutamate receptor 2/0.456
3il1B5DGlutamate receptor 2/0.456
3in6FMNUncharacterized protein/0.456
3vdqNAD3-hydroxybutyrate dehydrogenase/0.456
4rww2BALmo2692 protein/0.456
4zohFADPutative oxidoreductase FAD-binding subunit/0.456
5lc1NADL-threonine 3-dehydrogenase/0.456
1bsvNDPGDP-L-fucose synthase/0.455
1iziQ50Gag-Pol polyprotein3.4.23.160.455
1p84UQ6Cytochrome b/0.455
2q46NAPUncharacterized protein At5g02240/0.455
2uz1TPPBenzaldehyde lyase/0.455
3dm6757Beta-secretase 13.4.23.460.455
3ms421NGlycogen phosphorylase, muscle form2.4.1.10.455
3zmmF9JTyrosine-protein kinase JAK2/0.455
4gk4L90Ephrin type-A receptor 32.7.10.10.455
4i1iNADMalate dehydrogenase/0.455
1bvrNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.454
1dhrNADDihydropteridine reductase1.5.1.340.454
1gthFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.454
1ihxSNDGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.454
1mjbACOHistone acetyltransferase ESA1/0.454
1mrwK57Gag-Pol polyprotein3.4.23.160.454
1zeoC01Peroxisome proliferator-activated receptor gamma/0.454
2b4rNADGlyceraldehyde-3-phosphate dehydrogenase/0.454
2e8rSAHDiphthine synthase/0.454
2owgSAHDiphthine synthase/0.454
2y3sTIRTamL/0.454
2z54AB1Gag-Pol polyprotein3.4.23.160.454
3d7kD7KBenzaldehyde lyase/0.454
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.454
3r3sNADPutative oxidoreductase/0.454
4ke11R6Beta-secretase 13.4.23.460.454
4u7wNDPMxaA/0.454
4yqfGDPSeptin-9/0.454
1e3eNAIAlcohol dehydrogenase 41.1.1.10.453
1vf3GDNGlutathione S-transferase 32.5.1.180.453
1zrzBI1Protein kinase C iota type2.7.11.130.453
2givACOHistone acetyltransferase KAT8/0.453
2hr8SAHDiphthine synthase/0.453
2hutSAHDiphthine synthase/0.453
2iko7IGRenin3.4.23.150.453
2ji9TPWOxalyl-CoA decarboxylase4.1.1.80.453
2owuSAHDiphthine synthase/0.453
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.453
3a28NADL-2,3-butanediol dehydrogenase1.1.1.760.453
3a4vNADNDP-sugar epimerase/0.453
3ii43IIDihydrolipoyl dehydrogenase1.8.1.40.453
3iqhTYR_ASP_ILECysteine synthase2.5.1.470.453
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.453
3p82FMNPentaerythritol tetranitrate reductase/0.453
3zkyWT4Isopenicillin N synthase1.21.3.10.453
4mcc21XtRNA (guanine-N(1)-)-methyltransferase2.1.1.2280.453
4ocpADPN-acetylhexosamine 1-kinase2.7.1.1620.453
1c70L75Protease/0.452
1hb1OCVIsopenicillin N synthase1.21.3.10.452
1i3lNADUDP-glucose 4-epimerase/0.452
1okzUCN3-phosphoinositide-dependent protein kinase 12.7.11.10.452
1xe55FEPlasmepsin-23.4.23.390.452
2dxvSAHDiphthine synthase/0.452
2el0SAHDiphthine synthase/0.452
2ien017Gag-Pol polyprotein3.4.23.160.452
2p6kSAHDiphthine synthase/0.452
2qo9ANPEphrin type-A receptor 32.7.10.10.452
2z6rSAHDiphthine synthase/0.452
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.452
3kb1ADPIron-sulfur cluster carrier protein/0.452
3pgqGY3Acetyl-CoA carboxylase/0.452
3r9uFADThioredoxin reductase/0.452
4aqc88ATyrosine-protein kinase JAK2/0.452
1ai9NDPDihydrofolate reductase1.5.1.30.451
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1ju9NADAlcohol dehydrogenase E chain1.1.1.10.451
1o76CAMCamphor 5-monooxygenase1.14.15.10.451
2aa3AP0L-lactate dehydrogenase/0.451
2iodMYCDihydroflavonol 4-reductase1.1.1.2190.451
2p8hMY9Beta-secretase 13.4.23.460.451
2q7vFADThioredoxin reductase/0.451
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.451
2yj4ATPCopper-transporting ATPase/0.451
2z0ySAMRibosomal RNA small subunit methyltransferase E/0.451
3lqfNADGalactitol dehydrogenase/0.451
3sdkP3NProteasome subunit beta type-53.4.25.10.451
3sdkP3NProteasome subunit beta type-63.4.25.10.451
4kb9G79Protease/0.451
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.451
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.450
1hvlA76Gag-Pol polyprotein/0.450
2aidTHKGag-Pol polyprotein3.4.23.160.450
2egsSAHDiphthine synthase/0.450
2g2zCOZMalonyl CoA-acyl carrier protein transacylase2.3.1.390.450
2gnaGDUUDP-N-acetylglucosamine 4,6-dehydratase (inverting)4.2.1.1150.450
2p3c3TLProtease/0.450
2vci2GJHeat shock protein HSP 90-alpha/0.450
2xhd7T9Glutamate receptor 2/0.450
2znpK55Peroxisome proliferator-activated receptor delta/0.450
3bv2P38Mitogen-activated protein kinase 14/0.450
3ik6HCZGlutamate receptor 2/0.450
3oibFDAPutative acyl-CoA dehydrogenase/0.450
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.450
3wmxNADNAD dependent epimerase/dehydratase/0.450
4bfzZVZPantothenate kinase2.7.1.330.450
4df2FMNNADPH dehydrogenase/0.450
4jicFMNGTN Reductase/0.450
4qi5FADCellobiose dehydrogenase/0.450
5e8xSTUTGF-beta receptor type-12.7.11.300.450
5eccNAPDehydrofolate reductase type I/0.450
1ep1FMNDihydroorotate dehydrogenase B (NAD(+)), catalytic subunit1.3.1.140.449
1i7gAZ2Peroxisome proliferator-activated receptor alpha/0.449
1nhhANPDNA mismatch repair protein MutL/0.449
2bpw1INGag-Pol polyprotein3.4.23.160.449
2ejkSAHDiphthine synthase/0.449
2gjnFMNNitronate monooxygenase1.13.12.160.449
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.449
2p83MR0Beta-secretase 13.4.23.460.449
3bkbSTUTyrosine-protein kinase Fes/Fps2.7.10.20.449
3d84NDPDihydrofolate reductase1.5.1.30.449
3f03FMNPentaerythritol tetranitrate reductase/0.449
3oewNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.449
3rsv3RSBeta-secretase 13.4.23.460.449
4gk3L87Ephrin type-A receptor 32.7.10.10.449
4k6fNAPPutative Acetoacetyl-CoA reductase/0.449
4kkyCAMCamphor 5-monooxygenase1.14.15.10.449
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.449
4nd2A3DLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.449
4qysPLRTryptophan synthase beta chain 24.2.1.200.449
4rvuNDPProbable quinone reductase Qor (NADPH:quinone reductase) (Zeta-crystallin homolog protein)/0.449
4xldBRLPeroxisome proliferator-activated receptor gamma/0.449
1khrVIRStreptogramin A acetyltransferase2.3.10.448
1ma0NADAlcohol dehydrogenase class-31.1.1.10.448
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.448
1rl8RITGag-Pol polyprotein3.4.23.160.448
2b7zMK1Gag-Pol polyprotein/0.448
2e5aLAQLipoyltransferase 1, mitochondrial2.3.10.448
2e8hSAHDiphthine synthase/0.448
2fj1CTCTetracycline repressor protein class D/0.448
2gjlFMNNitronate monooxygenase1.13.12.160.448
2hu2NADC-terminal binding protein 1/0.448
2uwd2GGHeat shock protein HSP 90-alpha/0.448
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.448
2vtpLZ9Cyclin-dependent kinase 22.7.11.220.448
3atyFMNProstaglandin F2a synthase/0.448
3ed1GA3Gibberellin receptor GID1/0.448
3em0CHDFatty acid-binding protein 6, ileal (gastrotropin)/0.448
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.448
3uzp0CKCasein kinase I isoform delta2.7.11.10.448
4eutBX7Serine/threonine-protein kinase TBK12.7.11.10.448
4f32N323-oxoacyl-[acyl-carrier-protein] synthase 2/0.448
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.448
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.448
5f8fSFGPossible transcriptional regulatory protein/0.448
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.448
5k5zANPUncharacterized protein/0.448
1t2bCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.447
1t2dNADL-lactate dehydrogenase1.1.1.270.447
1u54ACPActivated CDC42 kinase 1/0.447
2a0wDIHPurine nucleoside phosphorylase2.4.2.10.447
2c29NAPDihydroflavonol 4-reductase/0.447
2dv3SAHDiphthine synthase/0.447
2dxxSAHDiphthine synthase/0.447
2eh4SAHDiphthine synthase/0.447
2ejjSAHDiphthine synthase/0.447
2ejvNADL-threonine 3-dehydrogenase/0.447
2ejzSAHDiphthine synthase/0.447
2evaADNMitogen-activated protein kinase kinase kinase 72.7.11.250.447
2ggqTTPDual sugar-1-phosphate nucleotidylyltransferase/0.447
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.447
2p2xSAHDiphthine synthase/0.447
3bm1FMNPutative NAD(P)H nitroreductase YdjA/0.447
3c15FOKAdenylate cyclase type 2/0.447
3c15FOKAdenylate cyclase type 5/0.447
3h06VBPGlutamate receptor 2/0.447
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.447
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.447
3ibqATPPyridoxal kinase/0.447
3mdmFJZCholesterol 24-hydroxylase/0.447
3oev3OEProteasome subunit beta type-53.4.25.10.447
3oev3OEProteasome subunit beta type-63.4.25.10.447
3pqbVGPPutative oxidoreductase/0.447
3qbfJHGGag-Pol polyprotein3.4.23.160.447
3s1dZIRCytokinin dehydrogenase 11.5.99.120.447
3toxNAPPutative oxidoreductase/0.447
4g7gVFVLanosterol 14-alpha-demethylase/0.447
5hs1VORLanosterol 14-alpha demethylase/0.447
1dr5NAPDihydrofolate reductase1.5.1.30.446
1errRALEstrogen receptor/0.446
1gaqFADFerredoxin/0.446
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.446
1qf5RPLAdenylosuccinate synthetase/0.446
1vikBAYGag-Pol polyprotein/0.446
1wbmBLLPol protein/0.446
2cibCM6Lanosterol 14-alpha demethylase1.14.13.700.446
2e07SAHDiphthine synthase/0.446
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.446
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.446
2npaMMBPeroxisome proliferator-activated receptor alpha/0.446
2vbdV10Isopenicillin N synthase1.21.3.10.446
2vv9IM9Cyclin-dependent kinase 22.7.11.220.446
2vx07X7Ephrin type-B receptor 42.7.10.10.446
2ztvNADD(-)-3-hydroxybutyrate dehydrogenase/0.446
3c1y2BADNA integrity scanning protein DisA/0.446
3ijoB4DGlutamate receptor 2/0.446
3ljtLA3A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.446
3nugNADPyridoxal 4-dehydrogenase1.1.1.1070.446
3otfCMPPotassium/sodium hyperpolarization-activated cyclic nucleotide-gated channel 4/0.446
3p7nFMNLight-activated DNA-binding protein EL222/0.446
3r2b05BMAP kinase-activated protein kinase 22.7.11.10.446
3r4b74TGag-Pol polyprotein/0.446
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.446
3sc13S13-phosphoinositide-dependent protein kinase 12.7.11.10.446
3tqhNDPQuinone oxidoreductase/0.446
3zcmPX3Integrase/0.446
4an4DUDPutative glycosyl transferase/0.446
4coxIMNProstaglandin G/H synthase 21.14.99.10.446
4dx7DM2Multidrug efflux pump subunit AcrB/0.446
4k3n1OTM17 leucyl aminopeptidase/0.446
4l0qNADAlcohol dehydrogenase class-3/0.446
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4nd4NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.446
4q73FADBifunctional protein PutA/0.446
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.446
4xx9ATP3-phosphoinositide-dependent protein kinase 12.7.11.10.446
5a3cNADSIR2 family protein/0.446
1ezvUQ6Cytochrome b/0.445
1fwkADPHomoserine kinase2.7.1.390.445
1hpxKNIGag-Pol polyprotein/0.445
1nffNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.445
1phhFADp-hydroxybenzoate hydroxylase/0.445
1w13SM1Urokinase-type plasminogen activator3.4.21.730.445
1w6hTITPlasmepsin-23.4.23.390.445
1wntNAPL-xylulose reductase1.1.1.100.445
1zptFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.445
2dsiSAHDiphthine synthase/0.445
2e7rSAHDiphthine synthase/0.445
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.445
2ek3SAHDiphthine synthase/0.445
2fzwNADAlcohol dehydrogenase class-31.1.1.10.445
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.445
3a9wNADNDP-sugar epimerase/0.445
3c212BADNA integrity scanning protein DisA/0.445
3cid318Beta-secretase 13.4.23.460.445
3cz7ACOHistone acetyltransferase RTT1092.3.1.480.445
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.445
3i2l2NCProtease/0.445
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.445
3o3pGDDGlycosyl transferase, family 2/0.445
4ambDUDPutative glycosyl transferase/0.445
4idtT28Mitogen-activated protein kinase kinase kinase 142.7.11.250.445
4okx198Androgen receptor/0.445
4q72FADBifunctional protein PutA/0.445
5hwoHMGHydroxymethylglutaryl-CoA synthase/0.445
1a72PADAlcohol dehydrogenase E chain1.1.1.10.444
1ae1NAPTropinone reductase 1/0.444
1mg5NAIAlcohol dehydrogenase1.1.1.10.444
1n49RITGag-Pol polyprotein3.4.23.160.444
1nooCAHCamphor 5-monooxygenase1.14.15.10.444
1rx1NAPDihydrofolate reductase1.5.1.30.444
2a94AP0L-lactate dehydrogenase1.1.1.270.444
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.444
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.444
2fy4COACholine O-acetyltransferase2.3.1.60.444
2op9WR1Orf1ab polyprotein/0.444
2vprTDCTetracycline repressor protein class H/0.444
2z3uCRRCytochrome P450/0.444
3cgeNDPCoenzyme A disulfide reductase/0.444
3d1z017Gag-Pol polyprotein3.4.23.160.444
3h8bNSYCathepsin L13.4.22.150.444
3hk1B64Fatty acid-binding protein, adipocyte/0.444
3iaeD7KBenzaldehyde lyase/0.444
3kjrNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.444
3l0lHC3Nuclear receptor ROR-gamma/0.444
3qpjN4IGag-Pol polyprotein3.4.23.160.444
3qpvADP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 32.7.1.1050.444
3t3r9PLCytochrome P450 2A61.14.130.444
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.444
3uleC69Actin-related protein 3/0.444
4eiqKCTPutative FAD-monooxygenase/0.444
4gk2L66Ephrin type-A receptor 32.7.10.10.444
4jr51LSNicotinamide phosphoribosyltransferase2.4.2.120.444
4n5nNAPAcetoacetyl-CoA reductase1.1.1.360.444
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.444
4rcvNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.444
4y0kNAPAntE/0.444
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.444
5kjfNAJAlcohol dehydrogenase E chain1.1.1.10.444
1cjuFOKAdenylate cyclase type 2/0.443
1cjuFOKAdenylate cyclase type 5/0.443
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.443
1eyqNARChalcone--flavonone isomerase 15.5.1.60.443
1fxsNAPGDP-L-fucose synthase/0.443
1lf3EH5Plasmepsin-23.4.23.390.443
1nzdUPGDNA beta-glucosyltransferase/0.443
1o97FADElectron transfer flavoprotein subunit alpha/0.443
1tehNADAlcohol dehydrogenase class-31.1.1.10.443
1zsf0ZSGag-Pol polyprotein3.4.23.160.443
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.443
2hy81STSerine/threonine-protein kinase PAK 12.7.11.10.443
2q5g1FAPeroxisome proliferator-activated receptor delta/0.443
2zshGA3Gibberellin receptor GID1A30.443
3b2sB2STrichothecene 3-O-acetyltransferase/0.443
3mpt1GKMitogen-activated protein kinase 14/0.443
3oafOAGDihydrofolate reductase1.5.1.30.443
3ooiSAMHistone-lysine N-methyltransferase, H3 lysine-36 and H4 lysine-20 specific2.1.1.430.443
3p62FMNPentaerythritol tetranitrate reductase/0.443
3phiNDPShikimate dehydrogenase (NADP(+))/0.443
3q44D50M1 family aminopeptidase3.4.110.443
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.443
3rn8RN8Glutamate receptor 2/0.443
3zpsEQMGag-Pol polyprotein3.4.23.160.443
4a4zANPAntiviral helicase SKI23.6.4.130.443
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.443
4cqlNADEstradiol 17-beta-dehydrogenase 81.1.1.620.443
4ewqMWLMitogen-activated protein kinase 14/0.443
4ocvANPAminoglycoside phosphotransferase/0.443
4xboSAHtRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ2.1.1.2000.443
5c7oNADGlyceraldehyde-3-phosphate dehydrogenase, testis-specific1.2.1.120.443
5c88COAN-alpha-acetyltransferase/0.443
1adfTADAlcohol dehydrogenase E chain1.1.1.10.442
1g6kNADGlucose 1-dehydrogenase1.1.1.470.442
1hdrNADDihydropteridine reductase1.5.1.340.442
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.442
1odyLP1Gag-Pol polyprotein3.4.23.160.442
1qrpHH0Pepsin A-43.4.23.10.442
1ykfNAPNADP-dependent isopropanol dehydrogenase1.1.1.800.442
2ag1TPPBenzaldehyde lyase/0.442
2b7aIZATyrosine-protein kinase JAK2/0.442
2cgu3A3Serine/threonine-protein kinase Chk12.7.11.10.442
2cmjNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.442
2d29FADAcyl-CoA dehydrogenase/0.442
2e8sSAHDiphthine synthase/0.442
2eeqSAHDiphthine synthase/0.442
2eh2SAHDiphthine synthase/0.442
2feuCAMCamphor 5-monooxygenase1.14.15.10.442
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.442
2q66ATPPoly(A) polymerase2.7.7.190.442
2rkvZBATrichothecene 3-O-acetyltransferase/0.442
2uzfCAA1,4-dihydroxy-2-naphthoyl-CoA synthase/0.442
3cgdCOACoenzyme A disulfide reductase/0.442
3clrFADElectron transfer flavoprotein subunit alpha/0.442
3docNADGlyceraldehyde-3-phosphate dehydrogenase/0.442
3hl0NADMaleylacetate reductase/0.442
3jv7NADSecondary alcohol dehydrogenase/0.442
3lpkZ76Beta-secretase 13.4.23.460.442
3o9aK14Pol polyprotein/0.442
4aknS5BBromodomain-containing protein 2/0.442
4alhA9PBromodomain-containing protein 2/0.442
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.442
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.442
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.442
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.442
1jpaANPEphrin type-B receptor 22.7.10.10.441
1kc1NDPdTDP-4-dehydrorhamnose reductase1.1.1.1330.441
1rbqKEUTrifunctional purine biosynthetic protein adenosine-32.1.2.20.441
1sguMK1Gag-Pol polyprotein3.4.23.160.441
1zoyUQ1Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial1.3.5.10.441
1zoyUQ1Succinate dehydrogenase cytochrome b560 subunit, mitochondrial/0.441
2a1mCAMCamphor 5-monooxygenase1.14.15.10.441
2a4fAAUV-1 protease/0.441
2cig1DGDihydrofolate reductase1.5.1.30.441
2ehlSAHDiphthine synthase/0.441
2ek2SAHDiphthine synthase/0.441
2f3eAXQBeta-secretase 13.4.23.460.441
2fy5SOPCholine O-acetyltransferase2.3.1.60.441
2hrbNAPCarbonyl reductase [NADPH] 31.1.1.1840.441
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.441
2is0I03Beta-secretase 13.4.23.460.441
2p6dSAHDiphthine synthase/0.441
2q85973UDP-N-acetylenolpyruvoylglucosamine reductase1.3.1.980.441
2r7b2533-phosphoinositide-dependent protein kinase 12.7.11.10.441
2rh9IGPTryptophan synthase alpha chain/0.441
2x0rNADMalate dehydrogenase/0.441
2y6o1N1Ephrin type-A receptor 42.7.10.10.441
2y8qADP5'-AMP-activated protein kinase subunit gamma-1/0.441
2znnS44Peroxisome proliferator-activated receptor alpha/0.441
3dv1AR9Beta-secretase 13.4.23.460.441
3f8pNADNADH oxidase/thioredoxin reductase/0.441
3fln3FNMitogen-activated protein kinase 14/0.441
3fx5KNIGag-Pol polyprotein3.4.23.160.441
3k2hLYABifunctional dihydrofolate reductase-thymidylate synthase/0.441
3keuATPPyridoxal kinase2.7.1.350.441
3mpjFADGlutaryl-CoA dehydrogenase1.3.99.320.441
3otwCOAPhosphopantetheine adenylyltransferase/0.441
3triNAPPyrroline-5-carboxylate reductase/0.441
3w2jQRODihydroorotate dehydrogenase (fumarate)1.3.98.10.441
4dbvNDPGlyceraldehyde-3-phosphate dehydrogenase/0.441
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.441
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.441
4udrFAD5-(hydroxymethyl)furfural oxidase/0.441
4y9lFADAcyl-CoA dehydrogenase family member 11/0.441
4y9qC2EUncharacterized protein/0.441
5jlaNADPutative short-chain dehydrogenase/reductase/0.441
1b16NAQAlcohol dehydrogenase1.1.1.10.440
1c6x3INProtease/0.440
1cg0IMOAdenylosuccinate synthetase/0.440
1difA85Gag-Pol polyprotein/0.440
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.440
1gg5E09NAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.440
1p0hACOMycothiol acetyltransferase2.3.1.1890.440
1p44NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.440
1thnADPAnti-sigma F factor/0.440
2a92NAIL-lactate dehydrogenase/0.440
2e15SAHDiphthine synthase/0.440
2eglSAHDiphthine synthase/0.440
2ep7NADGlyceraldehyde-3-phosphate dehydrogenase/0.440
2gqwFADFerredoxin reductase/0.440
2ji6TPWOxalyl-CoA decarboxylase4.1.1.80.440
2pckSAHDiphthine synthase/0.440
2qtvGNPSmall COPII coat GTPase SAR13.6.50.440
3axkNDPRibulose bisphosphate carboxylase large chain4.1.1.390.440
3ey9TDPPyruvate dehydrogenase [ubiquinone]1.2.5.10.440
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.440
3pqfNADL-lactate dehydrogenase1.1.1.270.440
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.440
3u9eCOALmo1369 protein/0.440
3uhl2NCGag-Pol polyprotein3.4.23.160.440
4aa5NQBMitogen-activated protein kinase 14/0.440
4cax646Glycylpeptide N-tetradecanoyltransferase2.3.1.970.440
4cdmFADDeoxyribodipyrimidine photolyase/0.440
4fweFADLysine-specific histone demethylase 1B10.440
4xd2NAIAlcohol dehydrogenase E chain1.1.1.10.440
5jsfNAD17-beta-hydroxysteroid dehydrogenase 141.1.10.440