sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Cavities are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 |
| PDB ID | HET | Uniprot Name | EC Number | Cavity Similarity |
Align |
|---|---|---|---|---|---|
| 5flt | VJJ | Carbonic anhydrase 2 | 4.2.1.1 | 1.000 | |
| 3kig | DA4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.853 | |
| 3n2p | AYX | Carbonic anhydrase 2 | 4.2.1.1 | 0.727 | |
| 1if6 | FBU | Carbonic anhydrase 2 | 4.2.1.1 | 0.707 | |
| 3qyk | IE2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.705 | |
| 1bn1 | AL5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.692 | |
| 3f4x | KLT | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 4kap | 1QV | Carbonic anhydrase 2 | 4.2.1.1 | 0.689 | |
| 3m2n | J74 | Carbonic anhydrase 2 | 4.2.1.1 | 0.685 | |
| 2weh | FB1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.684 | |
| 2eu3 | FF3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.682 | |
| 3m98 | E02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.678 | |
| 3m67 | E36 | Carbonic anhydrase 2 | 4.2.1.1 | 0.677 | |
| 1okl | MNS | Carbonic anhydrase 2 | 4.2.1.1 | 0.676 | |
| 3po6 | DT9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.675 | |
| 1kwq | SG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 1zsb | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.673 | |
| 3m5e | JDR | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3sbi | E90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.671 | |
| 3nb5 | R21 | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 4n16 | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.670 | |
| 1g52 | F2B | Carbonic anhydrase 2 | 4.2.1.1 | 0.669 | |
| 4m2r | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.668 | |
| 3eft | 3BS | Carbonic anhydrase 2 | 4.2.1.1 | 0.667 | |
| 1i8z | INL | Carbonic anhydrase 2 | 4.2.1.1 | 0.664 | |
| 1if8 | SBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.662 | |
| 1i91 | INQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3m2y | BE0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3t82 | SG4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.661 | |
| 3ffp | LC1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3t84 | SG6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.659 | |
| 3sax | E50 | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 4itp | 1GD | Carbonic anhydrase 2 | 4.2.1.1 | 0.658 | |
| 3s8x | E59 | Carbonic anhydrase 2 | 4.2.1.1 | 0.653 | |
| 3mhl | J71 | Carbonic anhydrase 2 | 4.2.1.1 | 0.651 | |
| 1bn4 | AL9 | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 2x7t | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.648 | |
| 1g54 | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.647 | |
| 4kni | E1E | Carbonic anhydrase 2 | 4.2.1.1 | 0.645 | |
| 3d9z | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3dc3 | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.644 | |
| 3m96 | E38 | Carbonic anhydrase 2 | 4.2.1.1 | 0.640 | |
| 1oq5 | CEL | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 3dcs | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.638 | |
| 2h15 | B19 | Carbonic anhydrase 2 | 4.2.1.1 | 0.637 | |
| 1g1d | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.636 | |
| 3m40 | J45 | Carbonic anhydrase 2 | 4.2.1.1 | 0.635 | |
| 3s9t | E49 | Carbonic anhydrase 2 | 4.2.1.1 | 0.632 | |
| 1bnn | AL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3dd8 | 2C7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3igp | DT7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 3mhi | J90 | Carbonic anhydrase 2 | 4.2.1.1 | 0.627 | |
| 1bnm | AL8 | Carbonic anhydrase 2 | 4.2.1.1 | 0.626 | |
| 3mho | J43 | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 3mzc | S6I | Carbonic anhydrase 2 | 4.2.1.1 | 0.624 | |
| 1if5 | FBT | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 4iwz | 1GO | Carbonic anhydrase 2 | 4.2.1.1 | 0.623 | |
| 1bnt | AL2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3hku | TOR | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3oys | OYS | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3t85 | SG7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.622 | |
| 3b4f | TUO | Carbonic anhydrase 2 | 4.2.1.1 | 0.620 | |
| 1g45 | FSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1okn | STB | Carbonic anhydrase 2 | 4.2.1.1 | 0.618 | |
| 1kwr | SG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.616 | |
| 1if7 | SBR | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 1ttm | 667 | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 4ito | MPX | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 4m2v | BZ1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.615 | |
| 2wej | FB2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 3ni5 | C1H | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 4k13 | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.614 | |
| 1a42 | BZU | Carbonic anhydrase 2 | 4.2.1.1 | 0.613 | |
| 4pxx | CHD | Carbonic anhydrase 2 | 4.2.1.1 | 0.612 | |
| 3mdz | EZL | Carbonic anhydrase 7 | 4.2.1.1 | 0.611 | |
| 3mna | DWH | Carbonic anhydrase 2 | 4.2.1.1 | 0.611 | |
| 3n0n | P9B | Carbonic anhydrase 2 | 4.2.1.1 | 0.610 | |
| 1if4 | FBS | Carbonic anhydrase 2 | 4.2.1.1 | 0.606 | |
| 3oim | VZ5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.605 | |
| 2wd2 | MS5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 2x7u | WZA | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 4bf6 | X0Q | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 4knj | E1F | Carbonic anhydrase 2 | 4.2.1.1 | 0.604 | |
| 1g4j | FFB | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 2weo | FBW | Carbonic anhydrase 2 | 4.2.1.1 | 0.603 | |
| 4ilx | 1EZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.602 | |
| 3sbh | E65 | Carbonic anhydrase 2 | 4.2.1.1 | 0.601 | |
| 3daz | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.600 | |
| 1jd0 | AZM | Carbonic anhydrase 12 | 4.2.1.1 | 0.599 | |
| 3myq | E27 | Carbonic anhydrase 2 | 4.2.1.1 | 0.599 | |
| 3k2f | NKX | Carbonic anhydrase 2 | 4.2.1.1 | 0.598 | |
| 1g4o | BSB | Carbonic anhydrase 2 | 4.2.1.1 | 0.597 | |
| 1i9q | IOF | Carbonic anhydrase 2 | 4.2.1.1 | 0.596 | |
| 2h4n | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.595 | |
| 1cny | EG3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 1i90 | INM | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 3mmf | D9H | Carbonic anhydrase 2 | 4.2.1.1 | 0.594 | |
| 1i9m | INW | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 1xq0 | 4TR | Carbonic anhydrase 2 | 4.2.1.1 | 0.592 | |
| 1xpz | 4TZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.591 | |
| 4bf1 | 9FK | Carbonic anhydrase 2 | 4.2.1.1 | 0.589 | |
| 2weg | FBV | Carbonic anhydrase 2 | 4.2.1.1 | 0.588 | |
| 1bn3 | AL6 | Carbonic anhydrase 2 | 4.2.1.1 | 0.585 | |
| 1yda | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.584 | |
| 3znc | BZ1 | Carbonic anhydrase 4 | 4.2.1.1 | 0.581 | |
| 3mhc | ARZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.580 | |
| 1bnw | TPD | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 3dd0 | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.579 | |
| 1bnv | AL7 | Carbonic anhydrase 2 | 4.2.1.1 | 0.578 | |
| 1cil | ETS | Carbonic anhydrase 2 | 4.2.1.1 | 0.576 | |
| 1bnq | AL4 | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 2pow | I7C | Carbonic anhydrase 2 | 4.2.1.1 | 0.575 | |
| 4ht2 | V50 | Carbonic anhydrase 12 | 4.2.1.1 | 0.575 | |
| 3n4b | WWZ | Carbonic anhydrase 2 | 4.2.1.1 | 0.569 | |
| 4kp8 | E1G | Carbonic anhydrase 12 | 4.2.1.1 | 0.569 | |
| 4lu3 | AZM | Carbonic anhydrase 14 | 4.2.1.1 | 0.569 | |
| 4x5s | AZM | Carbonic anhydrase (Carbonate dehydratase) | / | 0.564 | |
| 3l14 | I7B | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 3oy0 | OY0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.563 | |
| 3fw3 | ETS | Carbonic anhydrase 4 | 4.2.1.1 | 0.562 | |
| 1i9n | IOA | Carbonic anhydrase 2 | 4.2.1.1 | 0.559 | |
| 4uov | AZM | Carbonate dehydratase | / | 0.552 | |
| 3ml2 | SU0 | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 3n3j | WWV | Carbonic anhydrase 2 | 4.2.1.1 | 0.551 | |
| 3f7u | AG4 | Carbonic anhydrase 4 | 4.2.1.1 | 0.550 | |
| 3oik | WZB | Carbonic anhydrase 2 | 4.2.1.1 | 0.550 | |
| 1okm | SAB | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3oyq | OYQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.549 | |
| 3dbu | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.548 | |
| 4kp5 | E1F | Carbonic anhydrase 12 | 4.2.1.1 | 0.548 | |
| 3dcw | EZL | Carbonic anhydrase 2 | 4.2.1.1 | 0.547 | |
| 3p5l | IT5 | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 4mo8 | 2VQ | Carbonic anhydrase 2 | 4.2.1.1 | 0.544 | |
| 1cnw | EG1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.540 | |
| 3bet | CTF | Carbonic anhydrase 2 | 4.2.1.1 | 0.537 | |
| 3d8w | D8W | Carbonic anhydrase 2 | 4.2.1.1 | 0.532 | |
| 3f7b | AG5 | Carbonic anhydrase 4 | 4.2.1.1 | 0.531 | |
| 1i9p | IOE | Carbonic anhydrase 2 | 4.2.1.1 | 0.529 | |
| 4k0z | MZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.525 | |
| 4k0t | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.524 | |
| 1cnx | EG2 | Carbonic anhydrase 2 | 4.2.1.1 | 0.520 | |
| 4knn | E1F | Carbonic anhydrase 13 | 4.2.1.1 | 0.517 | |
| 1w6h | TIT | Plasmepsin-2 | 3.4.23.39 | 0.514 | |
| 4hu1 | V13 | Carbonic anhydrase 13 | 4.2.1.1 | 0.509 | |
| 1h50 | FMN | Pentaerythritol tetranitrate reductase | / | 0.506 | |
| 1o9b | NAI | Quinate/shikimate dehydrogenase | / | 0.504 | |
| 2pzj | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.504 | |
| 2cf6 | NAP | Cinnamyl alcohol dehydrogenase 5 | 1.1.1.195 | 0.502 | |
| 1dmy | AZM | Carbonic anhydrase 5A, mitochondrial | 4.2.1.1 | 0.501 | |
| 2a1h | GBN | Branched-chain-amino-acid aminotransferase, mitochondrial | 2.6.1.42 | 0.501 | |
| 3h3q | H13 | Collagen type IV alpha-3-binding protein | / | 0.498 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.497 | |
| 1vyr | FMN | Pentaerythritol tetranitrate reductase | / | 0.496 | |
| 4knm | E1E | Carbonic anhydrase 13 | 4.2.1.1 | 0.495 | |
| 2zs9 | ADP | Pantothenate kinase | 2.7.1.33 | 0.491 | |
| 3own | 3OX | Renin | 3.4.23.15 | 0.491 | |
| 4dz7 | D02 | Carbonic anhydrase 2 | 4.2.1.1 | 0.491 | |
| 4bfw | ZVW | Pantothenate kinase | 2.7.1.33 | 0.489 | |
| 1me6 | IVS | Plasmepsin-2 | 3.4.23.39 | 0.488 | |
| 3elb | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.488 | |
| 4xba | 5GP | Aprataxin-like protein | 3 | 0.488 | |
| 3s3v | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.487 | |
| 2q1q | OSP | Carbonic anhydrase 2 | 4.2.1.1 | 0.484 | |
| 1xe6 | 5FP | Plasmepsin-2 | 3.4.23.39 | 0.483 | |
| 1xz8 | 5GP | Bifunctional protein PyrR | 2.4.2.9 | 0.483 | |
| 2q1u | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.482 | |
| 3mpi | FAD | Glutaryl-CoA dehydrogenase | 1.3.99.32 | 0.482 | |
| 2a9y | 26A | Adenosine kinase | 2.7.1.20 | 0.481 | |
| 3f03 | FMN | Pentaerythritol tetranitrate reductase | / | 0.480 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.480 | |
| 1tll | FMN | Nitric oxide synthase, brain | 1.14.13.39 | 0.479 | |
| 2q1t | NAD | Putative nucleotide sugar epimerase/ dehydratase | / | 0.479 | |
| 3vsx | R32 | Renin | 3.4.23.15 | 0.479 | |
| 3h3r | 14H | Collagen type IV alpha-3-binding protein | / | 0.478 | |
| 3p62 | FMN | Pentaerythritol tetranitrate reductase | / | 0.478 | |
| 4a86 | H35 | Major pollen allergen Bet v 1-A | / | 0.478 | |
| 1rsz | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 2q7o | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.477 | |
| 2rqf | JH3 | Hemolymph juvenile hormone binding protein | / | 0.477 | |
| 3bl1 | BL1 | Carbonic anhydrase 2 | 4.2.1.1 | 0.477 | |
| 4iae | 1DX | Alr2278 protein | / | 0.477 | |
| 1rt9 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.476 | |
| 4jic | FMN | GTN Reductase | / | 0.476 | |
| 4yco | FMN | tRNA-dihydrouridine(16) synthase | / | 0.476 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.476 | |
| 2xup | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.475 | |
| 3l6j | Z90 | Alr2278 protein | / | 0.475 | |
| 3vyf | VYF | Renin | 3.4.23.15 | 0.474 | |
| 3b6p | TMP | Three-prime repair exonuclease 1 | 3.1.11.2 | 0.473 | |
| 3g1r | FIT | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.473 | |
| 3k8q | 22A | Purine nucleoside phosphorylase | 2.4.2.1 | 0.473 | |
| 3lxe | TOR | Carbonic anhydrase 1 | 4.2.1.1 | 0.473 | |
| 4a80 | 2AN | Major pollen allergen Bet v 1-A | / | 0.473 | |
| 2vat | COA | Acetyl-CoA--deacetylcephalosporin C acetyltransferase | 2.3.1.175 | 0.472 | |
| 2std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.471 | |
| 3dys | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.471 | |
| 1ics | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.470 | |
| 2q1s | NAI | Putative nucleotide sugar epimerase/ dehydratase | / | 0.470 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.470 | |
| 4f0r | MTA | 5-methylthioadenosine/S-adenosylhomocysteine deaminase | / | 0.470 | |
| 4iah | 1DX | Alr2278 protein | / | 0.470 | |
| 4n1g | CEI | Obelin | / | 0.470 | |
| 1lc3 | NAD | Biliverdin reductase A | 1.3.1.24 | 0.469 | |
| 1xdd | AAY | Integrin alpha-L | / | 0.469 | |
| 2ges | COK | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 2zs8 | ADP | Pantothenate kinase | 2.7.1.33 | 0.469 | |
| 3cos | NAD | Alcohol dehydrogenase 4 | 1.1.1.1 | 0.469 | |
| 3v2j | AZM | Carbonic anhydrase 2 | 4.2.1.1 | 0.469 | |
| 7std | CRP | Scytalone dehydratase | 4.2.1.94 | 0.469 | |
| 2hs8 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.468 | |
| 2j3q | TFL | Acetylcholinesterase | 3.1.1.7 | 0.468 | |
| 4eyw | L0R | Carnitine O-palmitoyltransferase 2, mitochondrial | 2.3.1.21 | 0.468 | |
| 4h9t | HL4 | Phosphotriesterase | / | 0.468 | |
| 1kbi | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.467 | |
| 1kkq | 471 | Peroxisome proliferator-activated receptor alpha | / | 0.467 | |
| 1mvt | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.467 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.467 | |
| 2ea4 | F79 | Methionine aminopeptidase 2 | / | 0.467 | |
| 2f7x | 4EA | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.467 | |
| 4dbz | NDP | Putative ketoacyl reductase | 1.3.1 | 0.467 | |
| 4eu9 | COA | Succinyl-CoA:acetate CoA-transferase | / | 0.467 | |
| 4gdd | NAI | UDP-galactopyranose mutase | / | 0.467 | |
| 4m0f | 1YK | Acetylcholinesterase | 3.1.1.7 | 0.467 | |
| 1rx0 | FAD | Isobutyryl-CoA dehydrogenase, mitochondrial | 1.3.99 | 0.466 | |
| 2y1t | DUD | SPBc2 prophage-derived deoxyuridine 5'-triphosphate nucleotidohydrolase YosS | 3.6.1.23 | 0.466 | |
| 3in6 | FMN | Uncharacterized protein | / | 0.466 | |
| 3k3e | PDB | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.466 | |
| 3vsw | R31 | Renin | 3.4.23.15 | 0.466 | |
| 4bfz | ZVZ | Pantothenate kinase | 2.7.1.33 | 0.466 | |
| 4w5k | PLP | Aspartate aminotransferase, mitochondrial | / | 0.466 | |
| 4y1b | NAP | AntE | / | 0.466 | |
| 1bnu | AL3 | Carbonic anhydrase 2 | 4.2.1.1 | 0.465 | |
| 3dyl | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.465 | |
| 3hgo | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.465 | |
| 4a81 | DXC | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4a86 | 2AN | Major pollen allergen Bet v 1-A | / | 0.465 | |
| 4du8 | 2P0 | Mevalonate diphosphate decarboxylase | / | 0.465 | |
| 4g95 | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.465 | |
| 1icp | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.464 | |
| 1n4s | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.464 | |
| 1vi2 | NAD | Quinate/shikimate dehydrogenase | / | 0.464 | |
| 2abb | FMN | Pentaerythritol tetranitrate reductase | / | 0.464 | |
| 2g5w | 8PG | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.464 | |
| 2qim | ZEA | Class 10 plant pathogenesis-related protein | / | 0.464 | |
| 2wqp | WQP | Polysialic acid capsule biosynthesis protein SiaC | / | 0.464 | |
| 2zvc | SAH | Precorrin-3 C17-methyltransferase | / | 0.464 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.464 | |
| 4drj | RAP | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.464 | |
| 4drj | RAP | Peptidyl-prolyl cis-trans isomerase FKBP4 | 5.2.1.8 | 0.464 | |
| 4m83 | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.464 | |
| 1bl4 | AP1 | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.463 | |
| 2a0w | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.463 | |
| 2uxo | TAC | HTH-type transcriptional regulator TtgR | / | 0.463 | |
| 3c1k | T15 | Prothrombin | 3.4.21.5 | 0.463 | |
| 3ixp | 834 | Ecdysone receptor | / | 0.463 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE26 | / | 0.463 | |
| 4x28 | FDA | Acyl-CoA dehydrogenase FadE27 | / | 0.463 | |
| 4ycp | FMN | tRNA-dihydrouridine(16) synthase | / | 0.463 | |
| 1dx6 | GNT | Acetylcholinesterase | 3.1.1.7 | 0.462 | |
| 1rr6 | IMH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.462 | |
| 3vyd | VYD | Renin | 3.4.23.15 | 0.462 | |
| 4bfu | ZVU | Pantothenate kinase | 2.7.1.33 | 0.462 | |
| 4c49 | HCY | Corticosteroid-binding globulin | / | 0.462 | |
| 4lzw | THM | Uridine phosphorylase | / | 0.462 | |
| 1gw2 | FER | Peroxidase C1A | 1.11.1.7 | 0.461 | |
| 1vbi | NAD | Malate/L-lactate dehydrogenase family protein | / | 0.461 | |
| 2ea2 | F77 | Methionine aminopeptidase 2 | / | 0.461 | |
| 2g1n | 1IG | Renin | 3.4.23.15 | 0.461 | |
| 2g1y | 5IG | Renin | 3.4.23.15 | 0.461 | |
| 2idk | C2F | Glycine N-methyltransferase | 2.1.1.20 | 0.461 | |
| 3pgh | FLP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.461 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.461 | |
| 4b4w | 9L9 | Bifunctional protein FolD | / | 0.461 | |
| 4xym | COA | Acyl-CoA synthetase (NDP forming) | / | 0.461 | |
| 1npd | NAD | Quinate/shikimate dehydrogenase | / | 0.460 | |
| 1o1s | 1NH | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.460 | |
| 1w6r | GNT | Acetylcholinesterase | 3.1.1.7 | 0.460 | |
| 2g1r | 3IG | Renin | 3.4.23.15 | 0.460 | |
| 2yq9 | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 2ztv | NAD | D(-)-3-hydroxybutyrate dehydrogenase | / | 0.460 | |
| 3fr5 | I4A | Fatty acid-binding protein, adipocyte | / | 0.460 | |
| 3zbs | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.460 | |
| 4dbc | 3QP | Aspartate aminotransferase | 2.6.1.1 | 0.460 | |
| 4fxy | 0W2 | Neurolysin, mitochondrial | 3.4.24.16 | 0.460 | |
| 1h22 | E10 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 1r5g | AO1 | Methionine aminopeptidase 2 | / | 0.459 | |
| 1tow | CRZ | Fatty acid-binding protein, adipocyte | / | 0.459 | |
| 2gev | COK | Pantothenate kinase | 2.7.1.33 | 0.459 | |
| 2whq | HI6 | Acetylcholinesterase | 3.1.1.7 | 0.459 | |
| 3otb | DGT | Probable tRNA(His) guanylyltransferase | 2.7.7.79 | 0.459 | |
| 3p67 | FMN | Pentaerythritol tetranitrate reductase | / | 0.459 | |
| 4pt3 | NDP | Aldehyde dehydrogenase | / | 0.459 | |
| 1ndh | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.458 | |
| 2ab8 | MTP | Adenosine kinase | 2.7.1.20 | 0.458 | |
| 2g22 | 6IG | Renin | 3.4.23.15 | 0.458 | |
| 2vig | FAD | Short-chain specific acyl-CoA dehydrogenase, mitochondrial | 1.3.8.1 | 0.458 | |
| 3img | BZ2 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3img | BZ3 | Pantothenate synthetase | 6.3.2.1 | 0.458 | |
| 3kjg | ADP | CO dehydrogenase/acetyl-CoA synthase complex, accessory protein CooC | / | 0.458 | |
| 3nl6 | TPS | Uncharacterized protein | / | 0.458 | |
| 4xrb | NDP | Possible bifunctional enzyme riboflavin biosynthesis protein RibD: diaminohydroxyphosphoribosylaminopyrimidine deaminase (Riboflavin-specific deaminase) + 5-amino-6-(5-phosphoribosylamino)uracil reduc | / | 0.458 | |
| 6std | MS2 | Scytalone dehydratase | 4.2.1.94 | 0.458 | |
| 1ld8 | U49 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.457 | |
| 1w34 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.457 | |
| 2iyf | ERY | Oleandomycin glycosyltransferase | 2.4.1 | 0.457 | |
| 3dyl | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 3eku | CY9 | Actin-5C | / | 0.457 | |
| 3gka | FMN | N-ethylmaleimide reductase | / | 0.457 | |
| 3p82 | FMN | Pentaerythritol tetranitrate reductase | / | 0.457 | |
| 3qj0 | QI3 | Botulinum neurotoxin type A | 3.4.24.69 | 0.457 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.457 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.457 | |
| 4j1f | 1HL | Beta-secretase 1 | 3.4.23.46 | 0.457 | |
| 4wda | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.457 | |
| 1fm4 | DXC | Major pollen allergen Bet v 1-L | / | 0.456 | |
| 1p0p | BCH | Cholinesterase | 3.1.1.8 | 0.456 | |
| 1rne | C60 | Renin | 3.4.23.15 | 0.456 | |
| 1toj | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.456 | |
| 2cek | N8T | Acetylcholinesterase | 3.1.1.7 | 0.456 | |
| 2g20 | L1A | Renin | 3.4.23.15 | 0.456 | |
| 2hxz | H7J | Cathepsin S | 3.4.22.27 | 0.456 | |
| 2qo5 | CHD | Fatty acid-binding protein 10-A, liver basic | / | 0.456 | |
| 2xtn | GTP | GTPase IMAP family member 2 | / | 0.456 | |
| 3dyq | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 3dys | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4gh6 | LUO | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.456 | |
| 4j8t | DOG | Uncharacterized PhzA/B-like protein PA3332 | / | 0.456 | |
| 5e5h | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.456 | |
| 3uon | QNB | Muscarinic acetylcholine receptor M2 | / | 0.456 | |
| 1akb | PPD | Aspartate aminotransferase, mitochondrial | 2.6.1.1 | 0.455 | |
| 1kh3 | ANP | Argininosuccinate synthase | / | 0.455 | |
| 1pd9 | CO4 | Dihydrofolate reductase | 1.5.1.3 | 0.455 | |
| 1zgb | A1E | Acetylcholinesterase | 3.1.1.7 | 0.455 | |
| 2a57 | CRM | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.455 | |
| 2g24 | 7IG | Renin | 3.4.23.15 | 0.455 | |
| 3cmf | PDN | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3cot | STR | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.455 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3eo8 | FMN | Putative nitroreductase | / | 0.455 | |
| 3n3z | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.455 | |
| 3p74 | FMN | Pentaerythritol tetranitrate reductase | / | 0.455 | |
| 3qgf | 46F | Genome polyprotein | 2.7.7.48 | 0.455 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.455 | |
| 4b65 | FAD | L-ornithine N(5)-monooxygenase | / | 0.455 | |
| 4jnk | ZHK | L-lactate dehydrogenase A chain | 1.1.1.27 | 0.455 | |
| 4oqy | NDP | (S)-imine reductase | / | 0.455 | |
| 4xsv | C5P | Ethanolamine-phosphate cytidylyltransferase | 2.7.7.14 | 0.455 | |
| 1h60 | STR | Pentaerythritol tetranitrate reductase | / | 0.454 | |
| 1hdc | CBO | 3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase | 1.1.1.53 | 0.454 | |
| 1kap | GLY_SER_ASN_SER | Serralysin | 3.4.24.40 | 0.454 | |
| 1uda | UFG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.454 | |
| 1uma | IN2 | Prothrombin | 3.4.21.5 | 0.454 | |
| 1y9d | TPP | Pyruvate oxidase | 1.2.3.3 | 0.454 | |
| 3cav | CI2 | 3-oxo-5-beta-steroid 4-dehydrogenase | / | 0.454 | |
| 3fhx | PLP | Pyridoxal kinase | 2.7.1.35 | 0.454 | |
| 3gfb | NAD | L-threonine 3-dehydrogenase | / | 0.454 | |
| 3rba | COD | Phosphopantetheine adenylyltransferase | / | 0.454 | |
| 3tqx | PLP | 2-amino-3-ketobutyrate coenzyme A ligase | / | 0.454 | |
| 4bfx | ZVX | Pantothenate kinase | 2.7.1.33 | 0.454 | |
| 1nvt | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.453 | |
| 1t7o | 152 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.453 | |
| 2xuo | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.453 | |
| 2znq | 401 | Peroxisome proliferator-activated receptor delta | / | 0.453 | |
| 3a6r | FMN | FMN-binding protein | / | 0.453 | |
| 3e34 | ED1 | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.453 | |
| 3e34 | ED1 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.453 | |
| 4a83 | DXC | Major pollen allergen Bet v 1-A | / | 0.453 | |
| 4a8v | 2AN | Major pollen allergen Bet v 1-J | / | 0.453 | |
| 4jqh | 1MF | Alr2278 protein | / | 0.453 | |
| 1q84 | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 1zdw | FLV | Prenyltransferase | / | 0.452 | |
| 1zw9 | H64 | ATP-dependent molecular chaperone HSP82 | / | 0.452 | |
| 2dfv | NAD | L-threonine 3-dehydrogenase | / | 0.452 | |
| 2g1s | 4IG | Renin | 3.4.23.15 | 0.452 | |
| 3eu5 | GBO | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.452 | |
| 3up4 | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.452 | |
| 4cuk | NAI | D-lactate dehydrogenase | / | 0.452 | |
| 4ey7 | E20 | Acetylcholinesterase | 3.1.1.7 | 0.452 | |
| 4mrm | 2BY | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.452 | |
| 4y35 | F90 | Endothiapepsin | 3.4.23.22 | 0.452 | |
| 1cbq | RE9 | Cellular retinoic acid-binding protein 2 | / | 0.451 | |
| 1h51 | FMN | Pentaerythritol tetranitrate reductase | / | 0.451 | |
| 1nl4 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.451 | |
| 1rx8 | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 2ev9 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.451 | |
| 2geu | COK | Pantothenate kinase | 2.7.1.33 | 0.451 | |
| 2p8u | COA | Hydroxymethylglutaryl-CoA synthase, cytoplasmic | 2.3.3.10 | 0.451 | |
| 2w6c | BM4 | Acetylcholinesterase | 3.1.1.7 | 0.451 | |
| 3otw | COA | Phosphopantetheine adenylyltransferase | / | 0.451 | |
| 3zs7 | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.451 | |
| 4e90 | 7RG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 4ke1 | 1R6 | Beta-secretase 1 | 3.4.23.46 | 0.451 | |
| 4ms1 | 381 | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.451 | |
| 4ocp | ADP | N-acetylhexosamine 1-kinase | 2.7.1.162 | 0.451 | |
| 1ld7 | U66 | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.450 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1wxj | IPL | Tryptophan synthase alpha chain | / | 0.450 | |
| 1x1d | SAH | C-20 methyltransferase | / | 0.450 | |
| 1xl8 | 152 | Peroxisomal carnitine O-octanoyltransferase | 2.3.1.137 | 0.450 | |
| 2fxu | BID | Actin, alpha skeletal muscle | / | 0.450 | |
| 2g1o | 2IG | Renin | 3.4.23.15 | 0.450 | |
| 2h3w | HC5 | Carnitine O-acetyltransferase | 2.3.1.7 | 0.450 | |
| 2zsd | COA | Pantothenate kinase | 2.7.1.33 | 0.450 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit alpha | 1.2.4.1 | 0.450 | |
| 3dva | TPW | Pyruvate dehydrogenase E1 component subunit beta | 1.2.4.1 | 0.450 | |
| 3giy | FMN | (S)-mandelate dehydrogenase | 1.1.99.31 | 0.450 | |
| 3jun | AKD | Phenazine biosynthesis protein A/B | / | 0.450 | |
| 3pdq | KC6 | Lysine-specific demethylase 4A | 1.14.11 | 0.450 | |
| 3w6h | AZM | Carbonic anhydrase 1 | 4.2.1.1 | 0.450 | |
| 4i6g | FAD | Cryptochrome-2 | / | 0.450 | |
| 4rvn | COA | Phenylacetate-coenzyme A ligase | / | 0.450 | |
| 1c9w | NAP | Aldose reductase-related protein 2 | / | 0.449 | |
| 1icq | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.449 | |
| 1kw8 | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.449 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.449 | |
| 2he5 | NDP | Aldo-keto reductase family 1 member C21 | 1.1.1 | 0.449 | |
| 2vyq | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.449 | |
| 3fap | ARD | Peptidyl-prolyl cis-trans isomerase FKBP1A | 5.2.1.8 | 0.449 | |
| 3fap | ARD | Serine/threonine-protein kinase mTOR | 2.7.11.1 | 0.449 | |
| 3o76 | GTB | Glutathione S-transferase P 1 | 2.5.1.18 | 0.449 | |
| 5dw6 | 0T1 | Succinyl-CoA:acetate CoA-transferase | / | 0.449 | |
| 4zj8 | SUV | Orexin receptor type 1 | / | 0.449 | |
| 1foa | UD1 | Alpha-1,3-mannosyl-glycoprotein 2-beta-N-acetylglucosaminyltransferase | 2.4.1.101 | 0.448 | |
| 1ib0 | FAD | NADH-cytochrome b5 reductase 3 | 1.6.2.2 | 0.448 | |
| 1qlh | NAD | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.448 | |
| 1teh | NAD | Alcohol dehydrogenase class-3 | 1.1.1.1 | 0.448 | |
| 1zgi | 382 | Prothrombin | 3.4.21.5 | 0.448 | |
| 2c29 | NAP | Dihydroflavonol 4-reductase | / | 0.448 | |
| 3d91 | REM | Renin | 3.4.23.15 | 0.448 | |
| 3dcc | D9Z | Carbonic anhydrase 2 | 4.2.1.1 | 0.448 | |
| 3dg8 | NDP | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.448 | |
| 3dy8 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3dyq | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.448 | |
| 3n4l | 842 | Beta-secretase 1 | 3.4.23.46 | 0.448 | |
| 3oaf | OAG | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 3orf | NAD | Dihydropteridine reductase | 1.5.1.34 | 0.448 | |
| 3phi | NDP | Shikimate dehydrogenase (NADP(+)) | / | 0.448 | |
| 3q7f | ED2 | Uncharacterized protein | / | 0.448 | |
| 3zei | AWH | O-acetylserine sulfhydrylase | / | 0.448 | |
| 4g09 | 0VD | Histidinol dehydrogenase | / | 0.448 | |
| 4gdy | 0X1 | Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial | 2.6.1.39 | 0.448 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.448 | |
| 4q72 | FAD | Bifunctional protein PutA | / | 0.448 | |
| 1c7o | PPG | Hemolysin | / | 0.447 | |
| 1eve | E20 | Acetylcholinesterase | 3.1.1.7 | 0.447 | |
| 1h63 | FMN | Pentaerythritol tetranitrate reductase | / | 0.447 | |
| 1obb | NAD | Alpha-glucosidase | 3.2.1.20 | 0.447 | |
| 1t4u | 81A | Prothrombin | 3.4.21.5 | 0.447 | |
| 1ype | UIP | Prothrombin | 3.4.21.5 | 0.447 | |
| 1zxm | ANP | DNA topoisomerase 2-alpha | 5.99.1.3 | 0.447 | |
| 2dvl | FAD | Acyl-CoA dehydrogenase | / | 0.447 | |
| 2q3r | FMN | 12-oxophytodienoate reductase 1 | 1.3.1.42 | 0.447 | |
| 2yoz | OVE | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.447 | |
| 3bxo | UPP | dTDP-3-amino-3,4,6-trideoxy-alpha-D-glucopyranose | / | 0.447 | |
| 3e8x | NAP | BH1520 protein | / | 0.447 | |
| 3jsw | JAR | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4psb | GA3 | Cytokinin-specific binding protein | / | 0.447 | |
| 5adh | APR | Alcohol dehydrogenase E chain | 1.1.1.1 | 0.447 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.447 | |
| 1bim | 0QB | Renin | 3.4.23.15 | 0.446 | |
| 1drh | NAP | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.446 | |
| 1rc4 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 1szg | FNS | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.446 | |
| 2aq8 | NAI | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.446 | |
| 2ddo | ATP | Pyridoxine/pyridoxal/pyridoxamine kinase | / | 0.446 | |
| 2f99 | AKV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.446 | |
| 2fr0 | NDP | 6-deoxyerythronolide-B synthase EryA1, modules 1 and 2 | / | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial | 1.2.4.4 | 0.446 | |
| 2j9f | THV | 2-oxoisovalerate dehydrogenase subunit beta, mitochondrial | 1.2.4.4 | 0.446 | |
| 2ldb | NAD | L-lactate dehydrogenase | 1.1.1.27 | 0.446 | |
| 2rlc | CHD | Choloylglycine hydrolase | 3.5.1.24 | 0.446 | |
| 3c27 | DKK | Prothrombin | 3.4.21.5 | 0.446 | |
| 3dzk | NMN | ADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 1 | 3.2.2.6 | 0.446 | |
| 3nsh | 957 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3rsv | 3RS | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 3ziu | LSS | Leucyl-tRNA synthetase | / | 0.446 | |
| 4ara | C56 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4arb | C57 | Acetylcholinesterase | 3.1.1.7 | 0.446 | |
| 4i0i | 957 | Beta-secretase 1 | 3.4.23.46 | 0.446 | |
| 4kby | C2E | Stimulator of interferon genes protein | / | 0.446 | |
| 4p9d | TMP | Deoxycytidylate deaminase | / | 0.446 | |
| 1a9y | UPG | UDP-glucose 4-epimerase | 5.1.3.2 | 0.445 | |
| 1ahg | TYR_PLP | Aspartate aminotransferase | 2.6.1.1 | 0.445 | |
| 1dgh | NDP | Catalase | 1.11.1.6 | 0.445 | |
| 1gtr | ATP | Glutamine--tRNA ligase | 6.1.1.18 | 0.445 | |
| 1o6q | R17 | Squalene--hopene cyclase | 4.2.1.129 | 0.445 | |
| 1qoq | IGP | Tryptophan synthase alpha chain | / | 0.445 | |
| 2bxq | IMN | Serum albumin | / | 0.445 | |
| 2chx | 090 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.445 | |
| 2dxd | ANP | Nucleoside diphosphate kinase | 2.7.4.6 | 0.445 | |
| 2pam | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.445 | |
| 2w9h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 2xui | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.445 | |
| 2zff | 53U | Prothrombin | 3.4.21.5 | 0.445 | |
| 3aez | GDP | Pantothenate kinase | 2.7.1.33 | 0.445 | |
| 3ivc | FG4 | Pantothenate synthetase | 6.3.2.1 | 0.445 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.445 | |
| 3wag | TYD | Glycosyltransferase | / | 0.445 | |
| 3wv9 | FEG | Hmd co-occurring protein HcgE | / | 0.445 | |
| 4a87 | NAR | Major pollen allergen Bet v 1-A | / | 0.445 | |
| 4elf | 35I | Dihydrofolate reductase | / | 0.445 | |
| 4f0e | 0RU | Poly [ADP-ribose] polymerase 15 | 2.4.2.30 | 0.445 | |
| 4yak | ACO | Acyl-CoA synthetase (NDP forming) | / | 0.445 | |
| 5jy1 | NAD | Putative short-chain dehydrogenase/reductase | / | 0.445 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.444 | |
| 1bxk | NAD | dTDP-glucose 4,6-dehydratase 2 | / | 0.444 | |
| 1n95 | HFP | Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha | / | 0.444 | |
| 1n95 | HFP | Protein farnesyltransferase subunit beta | 2.5.1.58 | 0.444 | |
| 1ps9 | MDE | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.444 | |
| 1qy8 | RDI | Endoplasmin | / | 0.444 | |
| 1x1a | SAM | C-20 methyltransferase | / | 0.444 | |
| 2cy0 | NAP | Shikimate dehydrogenase (NADP(+)) | / | 0.444 | |
| 2g8y | NAD | Hydroxycarboxylate dehydrogenase B | / | 0.444 | |
| 2pgt | GPR | Glutathione S-transferase P | 2.5.1.18 | 0.444 | |
| 2xuk | TZ5 | Acetylcholinesterase | 3.1.1.7 | 0.444 | |
| 3k3h | BYE | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 3p80 | P80 | Pentaerythritol tetranitrate reductase | / | 0.444 | |
| 3qi4 | IBM | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.444 | |
| 4dc0 | NDP | Putative ketoacyl reductase | 1.3.1 | 0.444 | |
| 4dpt | AGS | Mevalonate diphosphate decarboxylase | / | 0.444 | |
| 4q0k | GA3 | Phytohormone-binding protein | / | 0.444 | |
| 4rrr | A3T | Threonine--tRNA ligase | 6.1.1.3 | 0.444 | |
| 5a1t | NAI | L-lactate dehydrogenase | / | 0.444 | |
| 5dhh | DGW | Nociceptin receptor | / | 0.444 | |
| 1bws | NDP | GDP-L-fucose synthase | / | 0.443 | |
| 1jdt | MTA | Purine nucleoside phosphorylase | / | 0.443 | |
| 1toi | HCI | Aspartate aminotransferase | 2.6.1.1 | 0.443 | |
| 2b58 | COA | Diamine acetyltransferase 1 | / | 0.443 | |
| 2gv8 | NDP | Thiol-specific monooxygenase | 1.14.13 | 0.443 | |
| 2j09 | FMN | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.443 | |
| 2j9l | ATP | H(+)/Cl(-) exchange transporter 5 | / | 0.443 | |
| 2p8h | MY9 | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 2zsa | ADP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3af0 | GDP | Pantothenate kinase | 2.7.1.33 | 0.443 | |
| 3c0i | 3AM | Peripheral plasma membrane protein CASK | 2.7.11.1 | 0.443 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.443 | |
| 3jyp | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.443 | |
| 3mjr | AC2 | Deoxycytidine kinase | 2.7.1.74 | 0.443 | |
| 3w3l | RX8 | Toll-like receptor 8 | / | 0.443 | |
| 4lut | DCS | Alanine racemase | / | 0.443 | |
| 4mr7 | 2BV | Gamma-aminobutyric acid type B receptor subunit 1 | / | 0.443 | |
| 1psa | 0ZL | Pepsin A | 3.4.23.1 | 0.442 | |
| 1rfg | GMP | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 1szf | FMN | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.442 | |
| 1x1b | SAH | C-20 methyltransferase | / | 0.442 | |
| 1x27 | ASP_ASP_TYR_VAL_PTR | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.442 | |
| 1yw8 | A75 | Methionine aminopeptidase 2 | / | 0.442 | |
| 2a0x | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 2c1b | CQP | cAMP-dependent protein kinase catalytic subunit alpha | 2.7.11.11 | 0.442 | |
| 2dc1 | NAD | Probable L-aspartate dehydrogenase | / | 0.442 | |
| 2f98 | NGV | Aklanonic acid methyl ester cyclase AcmA | 5.5.1.23 | 0.442 | |
| 2fk8 | SAM | Hydroxymycolate synthase MmaA4 | 2.1.1 | 0.442 | |
| 2fon | FAD | Acyl-coenzyme A oxidase | / | 0.442 | |
| 2hs6 | FMN | 12-oxophytodienoate reductase 3 | 1.3.1.42 | 0.442 | |
| 2pak | TYD | TDP-4-oxo-6-deoxy-alpha-D-glucose-3,4-oxoisomerase | 5.3.2.3 | 0.442 | |
| 2r2m | I50 | Prothrombin | 3.4.21.5 | 0.442 | |
| 2wzw | NDP | Nitroreductase NfnB | / | 0.442 | |
| 2wzy | SQX | Soluble acetylcholine receptor | / | 0.442 | |
| 3bgs | DIH | Purine nucleoside phosphorylase | 2.4.2.1 | 0.442 | |
| 3bj7 | COA | Diamine acetyltransferase 1 | / | 0.442 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.442 | |
| 3i0p | NAD | Malate dehydrogenase, putative | / | 0.442 | |
| 3jyq | NAD | Quinate/shikimate dehydrogenase (NAD(+)) | / | 0.442 | |
| 3qeo | LLT | Deoxycytidine kinase | 2.7.1.74 | 0.442 | |
| 3qi1 | C6A | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 3t3r | 9PL | Cytochrome P450 2A6 | 1.14.13 | 0.442 | |
| 3uoz | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.442 | |
| 4bca | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.442 | |
| 4djw | 0KP | Beta-secretase 1 | 3.4.23.46 | 0.442 | |
| 4jtq | NAP | Aldo-keto reductase family 1 member C2 | / | 0.442 | |
| 4ph9 | IBP | Prostaglandin G/H synthase 2 | 1.14.99.1 | 0.442 | |
| 1e66 | HUX | Acetylcholinesterase | 3.1.1.7 | 0.441 | |
| 1fwk | ADP | Homoserine kinase | 2.7.1.39 | 0.441 | |
| 1r58 | AO5 | Methionine aminopeptidase 2 | / | 0.441 | |
| 2abj | CBC | Branched-chain-amino-acid aminotransferase, cytosolic | 2.6.1.42 | 0.441 | |
| 2anb | 5GP | Guanylate kinase | 2.7.4.8 | 0.441 | |
| 2dhf | DZF | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2gjl | FMN | Nitronate monooxygenase | 1.13.12.16 | 0.441 | |
| 2hu2 | NAD | C-terminal binding protein 1 | / | 0.441 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.441 | |
| 3bnk | FMN | Flavoredoxin | / | 0.441 | |
| 3h86 | AP5 | Adenylate kinase | / | 0.441 | |
| 3ryk | TYD | dTDP-4-dehydrorhamnose 3,5-epimerase | / | 0.441 | |
| 3t2v | KKJ | Peptidoglycan recognition protein 1 | / | 0.441 | |
| 3tjz | GNP | ADP-ribosylation factor 1 | / | 0.441 | |
| 3wid | NAP | Glucose 1-dehydrogenase | / | 0.441 | |
| 4bc7 | FAD | Alkyldihydroxyacetonephosphate synthase, peroxisomal | 2.5.1.26 | 0.441 | |
| 4c71 | 7RD | 3-oxoacyl-ACP synthase | / | 0.441 | |
| 4e2d | FMN | Dehydrogenase | / | 0.441 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4kla | CHD | Ferrochelatase, mitochondrial | 4.99.1.1 | 0.441 | |
| 4nvk | 2NY | Peroxidase | / | 0.441 | |
| 4prx | ADP | DNA gyrase subunit B | / | 0.441 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.441 | |
| 1fx9 | MJI | Phospholipase A2, major isoenzyme | 3.1.1.4 | 0.440 | |
| 1iay | AVG | 1-aminocyclopropane-1-carboxylate synthase 2 | 4.4.1.14 | 0.440 | |
| 1ja0 | FAD | NADPH--cytochrome P450 reductase | / | 0.440 | |
| 1nm6 | L86 | Prothrombin | 3.4.21.5 | 0.440 | |
| 2a5k | AZP | Replicase polyprotein 1ab | 3.4.22 | 0.440 | |
| 2b8v | 3BN | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 2c1z | KMP | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.440 | |
| 2c9z | QUE | Anthocyanidin 3-O-glucosyltransferase 2 | 2.4.1.115 | 0.440 | |
| 2vrb | NAP | Triphenylmethane reductase | / | 0.440 | |
| 2xuq | TZ4 | Acetylcholinesterase | 3.1.1.7 | 0.440 | |
| 3c3x | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.440 | |
| 3ean | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.440 | |
| 3gwf | NAP | Cyclohexanone monooxygenase | / | 0.440 | |
| 3h3s | H15 | Collagen type IV alpha-3-binding protein | / | 0.440 | |
| 3iu8 | T03 | Methionine aminopeptidase 2 | / | 0.440 | |
| 3mnr | SD1 | Heat shock protein HSP 90-alpha | / | 0.440 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3sxj | SAM | Putative methyltransferase | / | 0.440 | |
| 4a6r | TA8 | Probable aminotransferase | / | 0.440 | |
| 4bb3 | KKA | Isopenicillin N synthase | 1.21.3.1 | 0.440 | |
| 4eji | 0QA | Cytochrome P450 2A13 | 1.14.14.1 | 0.440 | |
| 4fry | NAD | Putative signal-transduction protein with CBS domains | / | 0.440 |