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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Cavity similarities measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Cavities are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299

Reference Protein Data Bank Entry :
PDB ID HET Uniprot Name EC Number
2vezACOGlucosamine 6-phosphate acetyltransferase, putative

Complex with similar cavities

PDB ID HET Uniprot Name EC Number Cavity
Similarity
Align
2vezACOGlucosamine 6-phosphate acetyltransferase, putative/1.000
2vxkCOAGlucosamine 6-phosphate acetyltransferase, putative/0.629
4h6zACOAlpha-tubulin N-acetyltransferase 1/0.544
4hkfACOAlpha-tubulin N-acetyltransferase 1/0.534
2cy2ACOProbable acetyltransferase/0.533
3f0aACOSpermidine N(1)-acetyltransferase/0.529
4phlPILPhosphodiesterase/0.516
2jdcCAOProbable acetyltransferase/0.515
1b87ACOAac(6')-Ii protein/0.512
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.510
1s7gNADNAD-dependent protein deacylase 2/0.506
3njoPYVAbscisic acid receptor PYR1/0.506
5kf2COAPredicted acetyltransferase/0.505
4ag9COAGlucosamine 6-phosphate N-acetyltransferase/0.504
4ckrDI1Epithelial discoidin domain-containing receptor 12.7.10.10.504
4h6uACOAlpha-tubulin N-acetyltransferase 1/0.502
1y60H4M5,6,7,8-tetrahydromethanopterin hydro-lyase4.2.1.1470.501
2vcmM11Isopenicillin N synthase1.21.3.10.501
4u9zCOAAlpha-tubulin N-acetyltransferase 1/0.500
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.499
1d3pBT3Prothrombin3.4.21.50.497
1gj5130Prothrombin3.4.21.50.497
2ejzSAHDiphthine synthase/0.497
3vf60H6Glucokinase2.7.1.20.496
1o2g696Prothrombin3.4.21.50.494
1rftPXMPyridoxal kinase2.7.1.350.494
2b01TUDPhospholipase A2, major isoenzyme3.1.1.40.493
4cs0ACOPanD regulatory factor/0.493
1blzACVIsopenicillin N synthase1.21.3.10.492
4a959MTGlycylpeptide N-tetradecanoyltransferase/0.492
4hfr14MCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.492
2e9aB28Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.491
2o28COAGlucosamine 6-phosphate N-acetyltransferase/0.490
4bb3KKAIsopenicillin N synthase1.21.3.10.490
3t5iSER_SER_CMT_FARRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.489
1p8dCO1Oxysterols receptor LXR-beta/0.488
3ar6TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.488
3vwdACOAlpha-tubulin N-acetyltransferase 1/0.488
3zkuHCVIsopenicillin N synthase1.21.3.10.488
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.487
4u9yCOAAlpha-tubulin N-acetyltransferase 1/0.487
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.486
2e0nSAHPrecorrin-2 C20-methyltransferase/0.486
2j3jHC4NADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.485
3bsyACOUDP-N-acetylbacillosamine N-acetyltransferase2.3.1.2030.485
3nxyD2HDihydrofolate reductase1.5.1.30.485
4ddl0JQcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.485
1ygkRRCPyridoxal kinase2.7.1.350.484
1hb3SCVIsopenicillin N synthase1.21.3.10.483
3zoiM2WIsopenicillin N synthase1.21.3.10.483
4bb6HD1Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.483
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.481
1puaCOAHAT A1/0.480
1qsnCOAHAT A1/0.480
3s41S41Glucokinase2.7.1.20.480
4b5oACOAlpha-tubulin N-acetyltransferase 1/0.480
4iaq2GM5-hydroxytryptamine receptor 1B/0.480
4ttjFMCPurine nucleoside phosphorylase DeoD-type/0.480
1n71COAAac(6')-Ii protein/0.479
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.479
5k2aZMAAdenosine receptor A2a/0.479
1yhjR6CPyridoxal kinase2.7.1.350.478
3up0D7SaceDAF-12/0.478
3p2oNADBifunctional protein FolD/0.477
3v94WYQPhosphodiesterase/0.477
4gs4ACOAlpha-tubulin N-acetyltransferase 1/0.477
4h7zGUNQueuine tRNA-ribosyltransferase2.4.2.290.477
5hwqCAAHydroxymethylglutaryl-CoA synthase/0.477
5kf9COAPredicted acetyltransferase/0.477
1pq944BOxysterols receptor LXR-beta/0.476
2gzl2AA2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase4.6.1.120.476
3gusN11Glutathione S-transferase P2.5.1.180.476
3qpoPFRcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.476
1dqaCOA3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.340.475
2r0pK2CPutative FAD-monooxygenase/0.475
1disBDMDihydrofolate reductase1.5.1.30.474
2vbpVB1Isopenicillin N synthase1.21.3.10.474
2yoj8Y6Genome polyprotein2.7.7.480.474
3sn7540cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
4fcb0T7cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
4llkMEWcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.474
1fxuGU7Purine nucleoside phosphorylase2.4.2.10.473
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.473
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.473
3djlFADPutative acyl-CoA dehydrogenase AidB1.3.990.473
3fhxPXLPyridoxal kinase2.7.1.350.473
4y1bNAPAntE/0.473
1nsgRADPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.472
1nsgRADSerine/threonine-protein kinase mTOR2.7.11.10.472
4zm6ACON-acetyl-beta-D glucosaminidase/0.472
1hb1OCVIsopenicillin N synthase1.21.3.10.471
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.471
2zevIPEGeranylgeranyl pyrophosphate synthase/0.471
3c3xNAPEugenol synthase 11.1.1.3180.471
3d7zGK5Mitogen-activated protein kinase 14/0.471
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.471
3fhxPLPPyridoxal kinase2.7.1.350.471
4ajm3A6cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.471
4k4eK4ETankyrase-12.4.2.300.471
1d3dBZTProthrombin3.4.21.50.470
1oc1ASVIsopenicillin N synthase1.21.3.10.470
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.470
4cryACOPanD regulatory factor/0.470
4v010LIFibroblast growth factor receptor 1 (Fms-related tyrosine kinase 2, Pfeiffer syndrome), isoform CRA_b/0.470
1aqxGTDGlutathione S-transferase P2.5.1.180.469
1qiqACCIsopenicillin N synthase1.21.3.10.469
1txtCAAHMG-CoA synthase/0.469
2b04CHOPhospholipase A2, major isoenzyme3.1.1.40.469
2rehFADNitroalkane oxidase1.7.3.10.469
3wixLC3Induced myeloid leukemia cell differentiation protein Mcl-1/0.469
3wqmB29Diterpene synthase3.1.7.80.469
4fhd0TTSpore photoproduct lyase/0.469
4imfSI3N-acetylneuraminate lyase/0.469
4twnB96Ephrin type-A receptor 32.7.10.10.469
5g53NECAdenosine receptor A2a/0.469
1bk0ACVIsopenicillin N synthase1.21.3.10.468
2agvTG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.468
2fm5M99cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2geuCOKPantothenate kinase2.7.1.330.468
2idkC2FGlycine N-methyltransferase2.1.1.200.468
2p15EZTEstrogen receptor/0.468
2pksG44Prothrombin3.4.21.50.468
4ajfF03cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.468
4jeyPLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.468
4p9dTMPDeoxycytidylate deaminase/0.468
5epvACPBlue-light-activated histidine kinase2.7.13.30.468
5uviZMAAdenosine receptor A2a/0.468
2bjsACVIsopenicillin N synthase1.21.3.10.467
2f3815MAldo-keto reductase family 1 member C3/0.467
2g8yNADHydroxycarboxylate dehydrogenase B/0.467
4gi2NAPCrotonyl-CoA carboxylase/reductase/0.467
4kbn25UDihydrofolate reductase1.5.1.30.467
7catNDPCatalase1.11.1.60.467
1gky5GPGuanylate kinase2.7.4.80.466
1hfqMOTDihydrofolate reductase1.5.1.30.466
1zdwFLVPrenyltransferase/0.466
2ouyCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.466
2wo7ASVIsopenicillin N synthase1.21.3.10.466
3ar4TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.466
3gytDL4Nuclear hormone receptor of the steroid/thyroid hormone receptors superfamily/0.466
3pg3DG7Mitogen-activated protein kinase 14/0.466
1euyQSIGlutamine--tRNA ligase6.1.1.180.465
2bxmIMNSerum albumin/0.465
4hf415HcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.465
1obnASVIsopenicillin N synthase1.21.3.10.464
1qjfACSIsopenicillin N synthase1.21.3.10.464
1yc2NADNAD-dependent protein deacylase 2/0.464
2cf8ESHProthrombin3.4.21.50.464
2poqISDTrans-1,2-dihydrobenzene-1,2-diol dehydrogenase1.3.1.200.464
2z4y252Geranylgeranyl pyrophosphate synthase/0.464
3ggs2FDPurine nucleoside phosphorylase2.4.2.10.464
3k4s0MOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.464
4drjRAPSerine/threonine-protein kinase mTOR2.7.11.10.464
4drjRAPPeptidyl-prolyl cis-trans isomerase FKBP45.2.1.80.464
5bt42LOBromodomain-containing protein 4/0.464
5dozNDPJamJ/0.464
1ej3CZHAequorin-2/0.463
1jwtBLIProthrombin3.4.21.50.463
1mu6CDAProthrombin3.4.21.50.463
1ygjRMCPyridoxal kinase2.7.1.350.463
2xvv9DNSerum albumin/0.463
3af1GDPPantothenate kinase2.7.1.330.463
3czr3CZCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.463
4a862ANMajor pollen allergen Bet v 1-A/0.463
5ab6CAANonspecific lipid-transfer protein, putative/0.463
1dr2TAPDihydrofolate reductase1.5.1.30.462
1p0pBCHCholinesterase3.1.1.80.462
1xomCIOcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.462
2ydoADNAdenosine receptor A2a/0.462
3aezGDPPantothenate kinase2.7.1.330.462
3c1oNAPEugenol synthase/0.462
3nmpPYVAbscisic acid receptor PYL2/0.462
3q9bB3NAcetylpolyamine amidohydrolase/0.462
4ajdF04cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.462
4dhyS41Glucokinase2.7.1.20.462
1rgsCMPcAMP-dependent protein kinase type I-alpha regulatory subunit/0.461
1y2d4DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
2q28ADPOxalyl-CoA decarboxylase4.1.1.80.461
3hmvHBTcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.461
3n3zIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.461
3nrrD16Bifunctional dihydrofolate reductase-thymidylate synthase/0.461
4hshQEIQueuine tRNA-ribosyltransferase2.4.2.290.461
4l1xNAPAldo-keto reductase family 1 member C2/0.461
2y0jAXCcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.460
3rj0BLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.460
1pt8ACOFormyl-CoA:oxalate CoA-transferase/0.459
1s3uTQDDihydrofolate reductase1.5.1.30.459
2iviACWIsopenicillin N synthase1.21.3.10.459
3wi2P98cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.459
4bftZVTPantothenate kinase2.7.1.330.459
4mvh2F5cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.459
4x28FDAAcyl-CoA dehydrogenase FadE26/0.459
4x28FDAAcyl-CoA dehydrogenase FadE27/0.459
5cmx0G6Prothrombin3.4.21.50.459
1dljUGAUDP-glucose 6-dehydrogenase/0.458
1efzPRFQueuine tRNA-ribosyltransferase2.4.2.290.458
1nzyBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.458
1qrsATPGlutamine--tRNA ligase6.1.1.180.458
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.458
3ar5TG1Sarcoplasmic/endoplasmic reticulum calcium ATPase 13.6.3.80.458
3thrC2FGlycine N-methyltransferase2.1.1.200.458
4boeCLRJapanin/0.458
4gutFADLysine-specific histone demethylase 1B10.458
1uhhCZPAequorin-2/0.457
2dhfDZFDihydrofolate reductase1.5.1.30.457
2g1n1IGRenin3.4.23.150.457
2msdGNPMHC class I alpha chain/0.457
2pr2DG1Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.457
3iktNADRedox-sensing transcriptional repressor Rex/0.457
3l0lHC3Nuclear receptor ROR-gamma/0.457
3t37FADPyridoxine 4-oxidase/0.457
4gcxPRFQueuine tRNA-ribosyltransferase2.4.2.290.457
4stdBFSScytalone dehydratase4.2.1.940.457
1kt3RTLRetinol-binding protein 4/0.456
1q0rAKTAclacinomycin methylesterase RdmC3.1.1.950.456
1trgCB3Thymidylate synthase/0.456
1zgcA2EAcetylcholinesterase3.1.1.70.456
2anmCDOProthrombin3.4.21.50.456
2vbdV10Isopenicillin N synthase1.21.3.10.456
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.456
3gncQQQGlutaryl-CoA dehydrogenase/0.456
3zkyWT4Isopenicillin N synthase1.21.3.10.456
4b5pACOAlpha-tubulin N-acetyltransferase 1/0.456
4h380YXDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.456
5jtbZMAAdenosine receptor A2a/0.456
1dghNDPCatalase1.11.1.60.455
1k4hAPQQueuine tRNA-ribosyltransferase2.4.2.290.455
1zw9H64ATP-dependent molecular chaperone HSP82/0.455
2ed3SAHDiphthine synthase/0.455
2in6839Wee1-like protein kinase2.7.10.20.455
2wksCB63-dehydroquinate dehydratase4.2.1.100.455
3aivHBO4-hydroxy-7-methoxy-3-oxo-3,4-dihydro-2H-1,4-benzoxazin-2-yl glucoside beta-D-glucosidase, chloroplastic3.2.1.1820.455
3g4gD71cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.455
4j6bPLOCytochrome P450 monooxygenase/0.455
4uugPXGBranched-chain amino acid aminotransferase, putative/0.455
1a4iNDPC-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.454
1dgfNDPCatalase1.11.1.60.454
1pqc444Oxysterols receptor LXR-beta/0.454
1pwyAC2Purine nucleoside phosphorylase2.4.2.10.454
1rpwDIDHTH-type transcriptional regulator QacR/0.454
1t7o152Carnitine O-acetyltransferase2.3.1.70.454
1z7yAA5Cysteine synthase 12.5.1.470.454
2e48FADD-amino-acid oxidase1.4.3.30.454
2wd8VGFPteridine reductase/0.454
2zevB71Geranylgeranyl pyrophosphate synthase/0.454
3cukFADD-amino-acid oxidase1.4.3.30.454
3eigMTXDihydrofolate reductase1.5.1.30.454
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
4j0jE35Tannase/0.454
4n3l2FNProthrombin3.4.21.50.454
4rn615UProthrombin3.4.21.50.454
1q63AIQQueuine tRNA-ribosyltransferase2.4.2.290.453
1so2666cGMP-inhibited 3',5'-cyclic phosphodiesterase B3.1.4.170.453
1xduSFGAclacinomycin 10-hydroxylase RdmB4.1.10.453
2bxoOPBSerum albumin/0.453
2clmF6FTryptophan synthase alpha chain/0.453
2zs9ADPPantothenate kinase2.7.1.330.453
3aosJH2Hemolymph juvenile hormone binding protein/0.453
3ch6311Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
3hkyIX6Genome polyprotein2.7.7.480.453
3ie3N11Glutathione S-transferase P2.5.1.180.453
3o9lLPNRenin3.4.23.150.453
3sl6JN8cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.453
4equG6ISerine/threonine-protein kinase 102.7.11.10.453
4jxxATPGlutamine--tRNA ligase6.1.1.180.453
4rgsV55Repressor protein/0.453
5fitAP2Bis(5'-adenosyl)-triphosphatase3.6.1.290.453
1fdwESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1g63FMNEpidermin decarboxylase4.1.10.452
1rsgFADPolyamine oxidase FMS1/0.452
1uydPU8Heat shock protein HSP 90-alpha/0.452
1v93FADMethylenetetrahydrofolate reductase/0.452
1ypgUIRProthrombin3.4.21.50.452
2o8h227cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.452
2ociTYCValacyclovir hydrolase3.10.452
2zsbADPPantothenate kinase2.7.1.330.452
3ey4352Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3g493G4Corticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.452
3uaxNOSPurine nucleoside phosphorylase DeoD-type/0.452
1bx9GLY_GGL_FOEGlutathione S-transferase F22.5.1.180.451
1gtrATPGlutamine--tRNA ligase6.1.1.180.451
1lf2R37Plasmepsin-23.4.23.390.451
1q4wDQUQueuine tRNA-ribosyltransferase2.4.2.290.451
2cleF6FTryptophan synthase alpha chain/0.451
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.451
2gqg1N1Tyrosine-protein kinase ABL12.7.10.20.451
2ntvP1HEnoyl-[acyl-carrier-protein] reductase [NADH]/0.451
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.451
3rsv3RSBeta-secretase 13.4.23.460.451
4a81DXCMajor pollen allergen Bet v 1-A/0.451
4biwANPSensor histidine kinase CpxA/0.451
4eywL0RCarnitine O-palmitoyltransferase 2, mitochondrial2.3.1.210.451
4fhf0TTSpore photoproduct lyase/0.451
1fdsESTEstradiol 17-beta-dehydrogenase 11.1.1.620.450
1fgiSU1Fibroblast growth factor receptor 1/0.450
1icqOPD12-oxophytodienoate reductase 11.3.1.420.450
1nqvLMZ6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.450
1qrpHH0Pepsin A-43.4.23.10.450
1stdBFSScytalone dehydratase4.2.1.940.450
1txzAPRProbable ADP-ribose 1''-phosphate phosphatase YML087W3.1.3.840.450
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.450
2clfF6FTryptophan synthase alpha chain/0.450
2ohiFMNType A flavoprotein FprA10.450
2y6fM9FIsopenicillin N synthase1.21.3.10.450
3k3hBYEHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.450
3tdaPN0Cytochrome P450 2D6/0.450
3wd9QPCcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.450
4blcNDPCatalase1.11.1.60.450
4necSAHPutative SAM-dependent methyltransferase/0.450
4pnmNU1Tankyrase-22.4.2.300.450
5dbfNDPIridoid synthase1.3.1.990.450
5k2cZMAAdenosine receptor A2a/0.450
1jtuLYBThymidylate synthase/0.449
1o6qR17Squalene--hopene cyclase4.2.1.1290.449
1ta6177Prothrombin3.4.21.50.449
2y60M8FIsopenicillin N synthase1.21.3.10.449
2yneYNEGlycylpeptide N-tetradecanoyltransferase/0.449
3eanNAPThioredoxin reductase 1, cytoplasmic1.8.1.90.449
3eta351Insulin receptor2.7.10.10.449
3fu83DMLaccase-11.10.3.20.449
3iakEV1cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.449
3ozc4CTS-methyl-5'-thioadenosine phosphorylase/0.449
3tubFPUTyrosine-protein kinase SYK2.7.10.20.449
4at0FADPossible succinate dehydrogenase/0.449
4dvi2IWTankyrase-12.4.2.300.449
4hqvQEIQueuine tRNA-ribosyltransferase2.4.2.290.449
4rh10TTSpore photoproduct lyase/0.449
4uhrNGIAdenosine receptor A2a/0.449
1q20PLOSulfotransferase family cytosolic 2B member 12.8.2.20.448
1r2jFADFkbI/0.448
1rfgGMPPurine nucleoside phosphorylase2.4.2.10.448
1t4u81AProthrombin3.4.21.50.448
1t4v14AProthrombin3.4.21.50.448
1uxnNAPNAD(P)-dependent glyceraldehyde-3-phosphate dehydrogenase/0.448
1w06W05Isopenicillin N synthase1.21.3.10.448
2bf7HBIPteridine reductase 11.5.1.330.448
2c1zKMPAnthocyanidin 3-O-glucosyltransferase 22.4.1.1150.448
2gjnFMNNitronate monooxygenase1.13.12.160.448
2jb4A14Isopenicillin N synthase1.21.3.10.448
2rabNADGlutathione amide reductase/0.448
2xvw9NRSerum albumin/0.448
3h3qH13Collagen type IV alpha-3-binding protein/0.448
3l6jZ90Alr2278 protein/0.448
3tvxPNXcAMP-specific 3',5'-cyclic phosphodiesterase 4A3.1.4.530.448
4agwNG7Proto-oncogene tyrosine-protein kinase Src2.7.10.20.448
4at4T6EBDNF/NT-3 growth factors receptor2.7.10.10.448
4bfxZVXPantothenate kinase2.7.1.330.448
4crzACOPanD regulatory factor/0.448
4dsbA8SAbscisic acid receptor PYL3/0.448
4jdcNADProbable pyrroline-5-carboxylate dehydrogenase RocA/0.448
4jva1ORcAMP-dependent protein kinase type II-beta regulatory subunit/0.448
4muw2F4cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
5cc9DDFDihydrofolate reductase1.5.1.30.448
1dhfFOLDihydrofolate reductase1.5.1.30.447
1kquBR4Phospholipase A2, membrane associated/0.447
1pj6FOLDimethylglycine oxidase1.5.3.100.447
1v48HA1Purine nucleoside phosphorylase2.4.2.10.447
1y6qTDI5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase3.2.2.90.447
2ewmNAD(S)-1-Phenylethanol dehydrogenase1.1.1.3110.447
2p8uCOAHydroxymethylglutaryl-CoA synthase, cytoplasmic2.3.3.100.447
2pdaTPPPyruvate synthase/0.447
2xviFADPutative flavin-containing monooxygenase/0.447
3c3dFO12-phospho-L-lactate transferase/0.447
3qri919Tyrosine-protein kinase ABL12.7.10.20.447
4ag7COAGlucosamine 6-phosphate N-acetyltransferase/0.447
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.447
4l17DNQGlutamate receptor 2/0.447
4mxeACON-acetyltransferase ESCO12.3.10.447
4tzt468Enoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.447
5esdTDP2-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.447
8catNDPCatalase1.11.1.60.447
5dhgDGVNociceptin receptor/0.447
1h5qNAPNADP-dependent mannitol dehydrogenase1.1.1.1380.446
1oynROLcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.446
1rd4L08Integrin alpha-L/0.446
1ry8RUTAldo-keto reductase family 1 member C3/0.446
1x8lOXRRetinol dehydratase/0.446
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.446
2zsdCOAPantothenate kinase2.7.1.330.446
3eksCY9Actin-5C/0.446
3hqdANPKinesin-like protein KIF11/0.446
3tfyCOAN-alpha-acetyltransferase 502.3.10.446
3uicNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.446
4bbhYBNGlycylpeptide N-tetradecanoyltransferase/0.446
4e907RGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.446
4iae1DXAlr2278 protein/0.446
4j6cSTRCytochrome P450 monooxygenase/0.446
4lm4JPZcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.446
4ms1381Gamma-aminobutyric acid type B receptor subunit 1/0.446
1digL37C-1-tetrahydrofolate synthase, cytoplasmic1.5.1.50.445
1lwiNAP3-alpha-hydroxysteroid dehydrogenase1.1.1.500.445
1mapKETAspartate aminotransferase, mitochondrial2.6.1.10.445
1ozqPRFQueuine tRNA-ribosyltransferase2.4.2.290.445
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
20gsCBDGlutathione S-transferase P2.5.1.180.445
2fb8215Serine/threonine-protein kinase B-raf2.7.11.10.445
2gjlFMNNitronate monooxygenase1.13.12.160.445
2j9fTHV2-oxoisovalerate dehydrogenase subunit alpha, mitochondrial1.2.4.40.445
2j9fTHV2-oxoisovalerate dehydrogenase subunit beta, mitochondrial1.2.4.40.445
2rd2QSIGlutamine--tRNA ligase6.1.1.180.445
3cic316Beta-secretase 13.4.23.460.445
3csjCBLGlutathione S-transferase P2.5.1.180.445
3g1rNAP3-oxo-5-beta-steroid 4-dehydrogenase/0.445
3l3rOAGDihydrofolate reductase1.5.1.30.445
3roeTHMNAD(P)H-hydrate epimerase5.1.99.60.445
3sgv2BJDitrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific)2.5.1.310.445
4a83DXCMajor pollen allergen Bet v 1-A/0.445
4jq4IMNAldo-keto reductase family 1 member C2/0.445
4oxyNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.445
4qpzTPPBenzaldehyde lyase/0.445
4z87GDPInosine-5'-monophosphate dehydrogenase/0.445
5kf2ACOPredicted acetyltransferase/0.445
6stdMS2Scytalone dehydratase4.2.1.940.445
7stdCRPScytalone dehydratase4.2.1.940.445
1a8t061Metallo-beta-lactamase type 2/0.444
1akbPPDAspartate aminotransferase, mitochondrial2.6.1.10.444
1bwkFMNNADPH dehydrogenase 11.6.99.10.444
1f3eDPZQueuine tRNA-ribosyltransferase2.4.2.290.444
1mabADPATP synthase subunit beta, mitochondrial3.6.3.140.444
1nm6L86Prothrombin3.4.21.50.444
1q5mNDPProstaglandin-E(2) 9-reductase1.1.1.1890.444
1ro6ROLcAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.444
1ypeUIPProthrombin3.4.21.50.444
2aotSAHHistamine N-methyltransferase2.1.1.80.444
2bifANP6-phosphofructo-2-kinase/fructose-2,6-bisphosphatase 42.7.1.1050.444
2fjeFADAdenylylsulfate reductase, subunit A (AprA)/0.444
2imkGTXAGAP009194-PA/0.444
2zruFMNIsopentenyl-diphosphate delta-isomerase/0.444
3jypNADQuinate/shikimate dehydrogenase (NAD(+))/0.444
3vmmP0DAlanine--anticapsin ligase/0.444
4eqrCOACoenzyme A disulfide reductase/0.444
4heu15JcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
4jlk1NODeoxycytidine kinase2.7.1.740.444
4jqh1MFAlr2278 protein/0.444
4kwhNAPReductase homolog/0.444
4paaTHGDimethylglycine dehydrogenase, mitochondrial1.5.8.40.444
4ubvCOASteroid 3-ketoacyl-CoA thiolase/0.444
4uohADPNucleoside diphosphate kinase/0.444
5iua6DXAdenosine receptor A2a/0.444
1kmsLIHDihydrofolate reductase1.5.1.30.443
1mvtDTMDihydrofolate reductase1.5.1.30.443
1pu9COAHAT A1/0.443
1toiHCIAspartate aminotransferase2.6.1.10.443
1xg5NAPDehydrogenase/reductase SDR family member 11/0.443
2b03TUDPhospholipase A2, major isoenzyme3.1.1.40.443
2io6330Wee1-like protein kinase2.7.10.20.443
2mm3CHOGastrotropin/0.443
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.443
2wlfACOPolysialic acid O-acetyltransferase/0.443
3b9lAZZSerum albumin/0.443
3g58988cAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.443
4j7hTRHPCZA361.3/0.443
4lsaBLDProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.443
4relKMPGlycosyltransferase/0.443
4zhiADPKinesin-like protein KIF11/0.443
5dp2NAPCurF/0.443
5emhNAPIridoid synthase1.3.1.990.443
5k2bZMAAdenosine receptor A2a/0.443
1e1qADPATP synthase subunit beta, mitochondrial3.6.3.140.442
1h36R88Squalene--hopene cyclase4.2.1.1290.442
1jxzBCA4-chlorobenzoyl coenzyme A dehalogenase3.8.1.70.442
1odnAPVIsopenicillin N synthase1.21.3.10.442
1ohkCOPDihydrofolate reductase1.5.1.30.442
1uhoVDNcGMP-specific 3',5'-cyclic phosphodiesterase/0.442
1xl8152Peroxisomal carnitine O-octanoyltransferase2.3.1.1370.442
1yryMSGPurine nucleoside phosphorylase2.4.2.10.442
2bu9HFVIsopenicillin N synthase1.21.3.10.442
2cjfRP43-dehydroquinate dehydratase4.2.1.100.442
2m3z1HFGag-Pol polyprotein/0.442
2ozuACOHistone acetyltransferase KAT6A/0.442
2r6jNDPEugenol synthase 11.1.1.3180.442
2yhuWHFPteridine reductase/0.442
3dv0TPWPyruvate dehydrogenase E1 component subunit alpha1.2.4.10.442
3dv0TPWPyruvate dehydrogenase E1 component subunit beta1.2.4.10.442
3elePLPAminotransferase/0.442
3hbfMYCFlavonoid 3-O-glucosyltransferase2.4.10.442
3nx2FERFerulic acid decarboxylase/0.442
3occDIHPurine nucleoside phosphorylase DeoD-type/0.442
3qm4PN0Cytochrome P450 2D6/0.442
4b4vL34Bifunctional protein FolD/0.442
4bfpSWYTankyrase-22.4.2.300.442
4da6GA2Purine nucleoside phosphorylase DeoD-type2.4.2.10.442
4jbtASDCytochrome P450 monooxygenase/0.442
4zqcF6FTryptophan synthase alpha chain/0.442
1ejiTHFSerine hydroxymethyltransferase, cytosolic/0.441
1yrsADPKinesin-like protein KIF11/0.441
2hk9NAPShikimate dehydrogenase (NADP(+))/0.441
2jh0701Prothrombin3.4.21.50.441
2og81N8Tyrosine-protein kinase Lck2.7.10.20.441
2uuk897Prothrombin3.4.21.50.441
2xdaJPS3-dehydroquinate dehydratase4.2.1.100.441
3bldPRFQueuine tRNA-ribosyltransferase2.4.2.290.441
3hf8ML0Tryptophan 5-hydroxylase 11.14.16.40.441
3otwCOAPhosphopantetheine adenylyltransferase/0.441
3s3vTOPDihydrofolate reductase1.5.1.30.441
3sixGDPNodulation protein Z/0.441
4bfuZVUPantothenate kinase2.7.1.330.441
4bfzZVZPantothenate kinase2.7.1.330.441
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.441
4hw319GInduced myeloid leukemia cell differentiation protein Mcl-1/0.441
4iarERM5-hydroxytryptamine receptor 1B/0.441
4j8tDOGUncharacterized PhzA/B-like protein PA3332/0.441
4ua3COAN-alpha-acetyltransferase 402.3.10.441
4xbfFADLysine-specific histone demethylase 1A10.441
1nceCB3Thymidylate synthase/0.440
1pkfEPDEpothilone C/D epoxidase1.140.440
1rdtL79Retinoic acid receptor RXR-alpha/0.440
1re0AFBADP-ribosylation factor 1/0.440
1re0AFBARF guanine-nucleotide exchange factor 1/0.440
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.440
2bdyUNBProthrombin3.4.21.50.440
2gbyBRNHTH-type transcriptional regulator QacR/0.440
2wetFADTryptophan 5-halogenase/0.440
2weyEV1cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
3ekuCY9Actin-5C/0.440
3n76CA23-dehydroquinate dehydratase4.2.1.100.440
3o57ZG2cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.440
3pm1ETHTH-type transcriptional regulator QacR/0.440
4a4o664Serine/threonine-protein kinase PLK12.7.11.210.440
4ajgF07cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.440
4jv41ORcAMP-dependent protein kinase type I-alpha regulatory subunit/0.440
4ea30NNNociceptin receptor/0.440