Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
5e9wSAHmRNA cap guanine-N7 methyltransferase2.1.1.56

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
5e9wSAHmRNA cap guanine-N7 methyltransferase2.1.1.561.000
1ri4SAMmRNA cap guanine-N7 methyltransferase2.1.1.560.585
5e8jSAHmRNA cap guanine-N7 methyltransferase2.1.1.560.570
1ri1GTGmRNA cap guanine-N7 methyltransferase2.1.1.560.562
1ri3SAHmRNA cap guanine-N7 methyltransferase2.1.1.560.535
1toiHCIAspartate aminotransferase2.6.1.10.524
2iyfERYOleandomycin glycosyltransferase2.4.10.523
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.509
2g1s4IGRenin3.4.23.150.505
2gcgNDPGlyoxylate reductase/hydroxypyruvate reductase1.1.1.790.505
4b65NDPL-ornithine N(5)-monooxygenase/0.502
3otwCOAPhosphopantetheine adenylyltransferase/0.500
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.498
1ja0NAPNADPH--cytochrome P450 reductase/0.497
2g1o2IGRenin3.4.23.150.496
3aezGDPPantothenate kinase2.7.1.330.494
1gc5ADPADP-dependent glucokinase2.7.1.1470.493
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.491
2il2LIXRenin3.4.23.150.491
2xfsJ01Uncharacterized protein/0.491
3imgBZ2Pantothenate synthetase6.3.2.10.490
3o03NAPDehydrogenase with different specificities (Related to short-chain alcohol dehydrogenase)/0.490
3h2sNDPPutative NADH-flavin reductase/0.489
2a1hGBNBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.488
3d3wNAPL-xylulose reductase1.1.1.100.488
2q1sNAIPutative nucleotide sugar epimerase/ dehydratase/0.487
3vx4ATPPutative ABC transporter, ATP-binding protein ComA/0.487
4m83ERYOleandomycin glycosyltransferase2.4.10.486
2g226IGRenin3.4.23.150.485
2x0fTRHWsaF/0.485
5d3qGDPDynamin-13.6.5.50.484
1g1aNADdTDP-glucose 4,6-dehydratase/0.483
2cmoM1LGlutamate receptor 2/0.483
4dh60KNBeta-secretase 13.4.23.460.483
4tuvCPZCytochrome P450 1191.140.483
3c1y2BADNA integrity scanning protein DisA/0.482
3p62FMNPentaerythritol tetranitrate reductase/0.482
1tehNADAlcohol dehydrogenase class-31.1.1.10.481
1dliUDXUDP-glucose 6-dehydrogenase/0.480
1naiNADUDP-glucose 4-epimerase5.1.3.20.480
3elbC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.480
3muoZPRProlyl endopeptidase/0.480
4df2FMNNADPH dehydrogenase/0.480
4r1fADPDNA topoisomerase 2-alpha5.99.1.30.480
1dljUGAUDP-glucose 6-dehydrogenase/0.479
1jqdSAHHistamine N-methyltransferase2.1.1.80.479
2b4tAESGlyceraldehyde-3-phosphate dehydrogenase/0.479
2gesCOKPantothenate kinase2.7.1.330.479
2iko7IGRenin3.4.23.150.479
4xguADPPutative pachytene checkpoint protein 2/0.479
4xnw2IDP2Y purinoceptor 1/0.479
1vjtNADAlpha-glucosidase, putative/0.478
2c20NADUDP-glucose 4-epimerase/0.478
4f1yCNIGlutamate receptor 3/0.478
2g1r3IGRenin3.4.23.150.477
3af1GDPPantothenate kinase2.7.1.330.477
3h06VBPGlutamate receptor 2/0.477
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.477
4m55NADUDP-glucuronic acid decarboxylase 14.1.1.350.477
1e3sNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.476
2dgnDOIAdenylosuccinate synthetase isozyme 1/0.476
3b4yF42F420-dependent glucose-6-phosphate dehydrogenase/0.476
3fhyATPPyridoxal kinase2.7.1.350.476
3ig6438Urokinase-type plasminogen activator3.4.21.730.476
2ph6712Beta-secretase 13.4.23.460.475
2zsaADPPantothenate kinase2.7.1.330.475
4b64NAPL-ornithine N(5)-monooxygenase/0.475
1bim0QBRenin3.4.23.150.474
2abbFMNPentaerythritol tetranitrate reductase/0.474
2geuCOKPantothenate kinase2.7.1.330.474
4b63NAPL-ornithine N(5)-monooxygenase/0.474
4hmz18TdTDP-4-dehydro-6-deoxyglucose 3-epimerase5.1.3.270.474
4rvdSAMD-mycarose 3-C-methyltransferase/0.474
2a2cADPN-acetylgalactosamine kinase2.7.1.1570.473
2d1yNADOxidoreductase, short-chain dehydrogenase/reductase family/0.473
3d91REMRenin3.4.23.150.473
3lu1NADUDP-N-acetylglucosamine 4-epimerase/0.473
4b63FADL-ornithine N(5)-monooxygenase/0.473
4blrUTPNTPase P4/0.473
2qs3UBEGlutamate receptor ionotropic, kainate 1/0.472
3rudNADUDP-N-acetylglucosamine 4-epimerase/0.472
4yvz3ATDNA integrity scanning protein DisA/0.472
5c1mCLRMu-type opioid receptor/0.472
2hv9SFGmRNA cap guanine-N7 methyltransferase2.1.1.560.471
3c212BADNA integrity scanning protein DisA/0.471
3lqsPSZD-alanine aminotransferase2.6.1.210.471
3ruaNADUDP-N-acetylglucosamine 4-epimerase/0.471
3s5wFADL-ornithine N(5)-monooxygenase/0.471
4qaiFMNNADPH dehydrogenase/0.471
4yaw2AMNADPH--cytochrome P450 reductase/0.471
1x1bSAHC-20 methyltransferase/0.470
2j07HDFDeoxyribodipyrimidine photo-lyase4.1.99.30.470
3ogwIMNLactoperoxidase1.11.1.70.470
1xe65FPPlasmepsin-23.4.23.390.469
2g21L1BRenin3.4.23.150.469
2gv8NDPThiol-specific monooxygenase1.14.130.469
2o23NAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.469
2q1uNADPutative nucleotide sugar epimerase/ dehydratase/0.469
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.469
3fzfATPHeat shock cognate 71 kDa protein/0.469
3rufNADUDP-N-acetylglucosamine 4-epimerase/0.469
3ukoNADAlcohol dehydrogenase class-3/0.469
4b64FADL-ornithine N(5)-monooxygenase/0.469
4lk3NADUDP-glucuronic acid decarboxylase 14.1.1.350.469
4nmdFDABifunctional protein PutA/0.469
1h51FMNPentaerythritol tetranitrate reductase/0.468
1h74ADPHomoserine kinase2.7.1.390.468
1u7tNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.468
2ylrNAPPhenylacetone monooxygenase1.14.13.920.468
3bgxTMPThymidylate synthase/0.468
3fr5I4AFatty acid-binding protein, adipocyte/0.468
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.468
3qviK95HAP protein/0.468
3te5NAI5'-AMP-activated protein kinase subunit gamma/0.468
4frkDWDBeta-secretase 13.4.23.460.468
4gk3L87Ephrin type-A receptor 32.7.10.10.468
4ohf5GPCytosolic IMP-GMP specific 5'-nucleotidase/0.468
4xsvCTPEthanolamine-phosphate cytidylyltransferase2.7.7.140.468
4dieC5PCytidylate kinase/0.467
4id9NADPutative UDP-glucose 4-epimerase/0.467
1bduDURThymidylate synthase/0.466
1bsvNDPGDP-L-fucose synthase/0.466
1fxsNAPGDP-L-fucose synthase/0.466
1nl4HFPProtein farnesyltransferase subunit beta2.5.1.580.466
1wngSAHDiphthine synthase/0.466
2a0xDIHPurine nucleoside phosphorylase2.4.2.10.466
3bm1FMNPutative NAD(P)H nitroreductase YdjA/0.466
3h4vNAPPteridine reductase 11.5.1.330.466
3mauEXTPutative sphingosine-1-phosphate lyase/0.466
3nxxNDPDihydrofolate reductase1.5.1.30.466
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.466
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.466
4egbNADdTDP-glucose 4,6-dehydratase/0.466
4hwkNAPSepiapterin reductase1.1.1.1530.466
4xbjIN5Alanine racemase, biosynthetic/0.466
5f8eSAHPossible transcriptional regulatory protein/0.466
1l7x700Glycogen phosphorylase, liver form2.4.1.10.465
2dvlFADAcyl-CoA dehydrogenase/0.465
2pzjNADPutative nucleotide sugar epimerase/ dehydratase/0.465
2q14ADPPhosphohydrolase/0.465
2y5s78HDihydropteroate synthase/0.465
3hl0NADMaleylacetate reductase/0.465
1h7wFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.464
1uymPU3Heat shock protein HSP 90-beta/0.464
1zxnADPDNA topoisomerase 2-alpha5.99.1.30.464
2futH1SHeparin and heparin-sulfate lyase/0.464
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.464
3rueNADUDP-N-acetylglucosamine 4-epimerase/0.464
3to3ATPPetrobactin biosynthesis protein AsbB/0.464
4bf9FMNtRNA-dihydrouridine(16) synthase/0.464
3isjA8DPantothenate synthetase6.3.2.10.463
4hp8NAP2-deoxy-D-gluconate 3-dehydrogenase/0.463
1ascNPLAspartate aminotransferase2.6.1.10.462
1vf3GDNGlutathione S-transferase 32.5.1.180.462
1xe55FEPlasmepsin-23.4.23.390.462
1yw8A75Methionine aminopeptidase 2/0.462
2omeNADC-terminal-binding protein 2/0.462
2zjmF1MBeta-secretase 13.4.23.460.462
3nubUD0UDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.462
3rsv3RSBeta-secretase 13.4.23.460.462
3toxNAPPutative oxidoreductase/0.462
4j7uNAPSepiapterin reductase1.1.1.1530.462
4j7xNAPSepiapterin reductase1.1.1.1530.462
4ycpFMNtRNA-dihydrouridine(16) synthase/0.462
5cfpC2EStimulator of interferon genes protein/0.462
5eioNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.462
1tytFADTrypanothione reductase1.8.1.120.461
2g247IGRenin3.4.23.150.461
2i4qUA4Renin3.4.23.150.461
2yxuATPPyridoxal kinase2.7.1.350.461
3d8vUD1Bifunctional protein GlmU/0.461
3fp0FP015-O-acetyltransferase/0.461
3w5hFADNADH-cytochrome b5 reductase 31.6.2.20.461
4jnkZHKL-lactate dehydrogenase A chain1.1.1.270.461
4o63NADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.461
4twrNADNAD binding site:NAD-dependent epimerase/dehydratase:UDP-glucose 4-epimerase/0.461
4yqfGDPSeptin-9/0.461
5einNAP[LysW]-L-2-aminoadipate 6-phosphate reductase/0.461
1h60STRPentaerythritol tetranitrate reductase/0.460
1r6uTYMTryptophan--tRNA ligase, cytoplasmic6.1.1.20.460
3bgxMEFThymidylate synthase/0.460
3hyoADPPyridoxal kinase/0.460
3mjeNDPAmphB/0.460
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.460
3p93KDGD-galactonate dehydratase family member ManD4.2.10.460
3q3cNADNAD-dependent L-serine dehydrogenase/0.460
4cjx9L9C-1-tetrahydrofolate synthase, cytoplasmic, putative/0.460
4dbzNDPPutative ketoacyl reductase1.3.10.460
4djaFAD(6-4) photolyase/0.460
4giu636Anthranilate phosphoribosyltransferase/0.460
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.460
1kt8ILPBranched-chain-amino-acid aminotransferase, mitochondrial2.6.1.420.459
1orrCDPCDP-paratose 2-epimerase/0.459
2vprTDCTetracycline repressor protein class H/0.459
2zgb21UProthrombin3.4.21.50.459
3adaNADSubunit alpha of sarocosine oxidase/0.459
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.459
4askK0ILysine-specific demethylase 6B1.14.110.459
4bv9NDPKetimine reductase mu-crystallin1.5.1.250.459
4fj2NAP17beta-hydroxysteroid dehydrogenase/0.459
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.458
1gvrTNLPentaerythritol tetranitrate reductase/0.458
1x27ASP_TYR_VAL_HIS_PTRTyrosine-protein kinase Lck2.7.10.20.458
2e07SAHDiphthine synthase/0.458
2e8qSAHDiphthine synthase/0.458
3csoXNIGenome polyprotein2.7.7.480.458
3dj4UD1Bifunctional protein GlmU/0.458
4a6rTA8Probable aminotransferase/0.458
4tsrIHSPeriplasmic AppA protein3.1.3.20.458
4wsoNADProbable nicotinate-nucleotide adenylyltransferase/0.458
5c77SAHProtein arginine N-methyltransferase SFM1/0.458
5js6NAD17-beta-hydroxysteroid dehydrogenase 141.1.10.458
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.457
1nuuNADNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.457
1snyNAPLD36273p/0.457
1tysDHFThymidylate synthase/0.457
2o1sTDP1-deoxy-D-xylulose-5-phosphate synthase2.2.1.70.457
2yvwEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.457
3bkkKAFAngiotensin-converting enzyme3.2.10.457
3ieuGDPGTPase Era/0.457
3rfaSAMDual-specificity RNA methyltransferase RlmN/0.457
3wagTYDGlycosyltransferase/0.457
4d89BXDBeta-secretase 13.4.23.460.457
4hxyNDPPlm1/0.457
4r1lADPPhenylacetate-coenzyme A ligase/0.457
5fd8A5APutative carboxypeptidase yocD/0.457
1b5eDCMDeoxycytidylate 5-hydroxymethyltransferase2.1.2.80.456
2g8yNADHydroxycarboxylate dehydrogenase B/0.456
3mw9NAIGlutamate dehydrogenase 1, mitochondrial1.4.1.30.456
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.456
4h1vGNPDynamin-1-like protein3.6.5.50.456
4z3dNDPCarbonyl reductase [NADPH] 11.1.1.1840.456
1f4gTP4Thymidylate synthase/0.455
2g1n1IGRenin3.4.23.150.455
2h55DZ8Heat shock protein HSP 90-alpha/0.455
3fceATPD-alanine--poly(phosphoribitol) ligase subunit 1/0.455
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.455
3nk7SAM23S rRNA (adenosine(1067)-2'-O)-methyltransferase/0.455
3ru7NADUDP-N-acetylglucosamine 4-epimerase/0.455
3t4nADP5'-AMP-activated protein kinase subunit gamma/0.455
3tjlFMNNADPH dehydrogenase/0.455
4dc0NDPPutative ketoacyl reductase1.3.10.455
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.455
1eq2NAPADP-L-glycero-D-manno-heptose-6-epimerase/0.454
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.454
1ma0NADAlcohol dehydrogenase class-31.1.1.10.454
2dxxSAHDiphthine synthase/0.454
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.454
2zcvNDPQuinone oxidoreductase 21.6.5.20.454
3bw4FMNPutative 2-nitropropane dioxygenase/0.454
3keuATPPyridoxal kinase2.7.1.350.454
3nmpPYVAbscisic acid receptor PYL2/0.454
3tjzGNPADP-ribosylation factor 1/0.454
3ufl508Beta-secretase 13.4.23.460.454
4eplJAIJasmonic acid-amido synthetase JAR16.3.20.454
4zowCLMMultidrug transporter MdfA/0.454
5bt9NAP3-oxoacyl-(Acyl-carrier-protein) reductase/0.454
1cg0IMOAdenylosuccinate synthetase/0.453
1zxmANPDNA topoisomerase 2-alpha5.99.1.30.453
2emrSAHDiphthine synthase/0.453
2huqSAHDiphthine synthase/0.453
2xpwOTCTetracycline repressor protein class D/0.453
2yq92AM2',3'-cyclic-nucleotide 3'-phosphodiesterase3.1.4.370.453
3d64NADAdenosylhomocysteinase/0.453
3e34ED1Protein farnesyltransferase/geranylgeranyltransferase type-1 subunit alpha/0.453
3e34ED1Protein farnesyltransferase subunit beta2.5.1.580.453
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.453
3f3sNADLambda-crystallin homolog/0.453
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.453
4b66NAPL-ornithine N(5)-monooxygenase/0.453
4fj1NAP17beta-hydroxysteroid dehydrogenase/0.453
4ge70K5Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.453
5czySAMEukaryotic huntingtin interacting protein B/0.453
1ddrMTXDihydrofolate reductase1.5.1.30.452
1gteFADDihydropyrimidine dehydrogenase [NADP(+)]1.3.1.20.452
1hwzNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.452
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.452
1ld7U66Protein farnesyltransferase subunit beta2.5.1.580.452
1siqFADGlutaryl-CoA dehydrogenase, mitochondrial1.3.8.60.452
1w6hTITPlasmepsin-23.4.23.390.452
2bgmNAJSecoisolariciresinol dehydrogenase1.1.1.3310.452
2e16SAHDiphthine synthase/0.452
2gmhFADElectron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial1.5.5.10.452
2r2nKYNKynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.452
3d28B34Genome polyprotein2.7.7.480.452
3d3xARG_ILE_MET_GLU_NH2Type E botulinum toxin/0.452
3eo8FMNPutative nitroreductase/0.452
3hz5Z64Heat shock protein HSP 90-alpha/0.452
3ivgFG5Pantothenate synthetase6.3.2.10.452
3kruFMNNADH:flavin oxidoreductase/NADH oxidase/0.452
3rk1ATPN-type ATP pyrophosphatase superfamily/0.452
3vydVYDRenin3.4.23.150.452
3zpoK0IHistone demethylase UTY1.14.110.452
4gv25MEPoly [ADP-ribose] polymerase 32.4.2.300.452
4h8aNAIUreidoglycolate dehydrogenase (NAD(+))1.1.1.3500.452
4nwzFADFAD-dependent pyridine nucleotide-disulfide oxidoreductase/0.452
1h50FMNPentaerythritol tetranitrate reductase/0.451
1ia1NDPDihydrofolate reductase1.5.1.30.451
1ib0FADNADH-cytochrome b5 reductase 31.6.2.20.451
1qf5RPLAdenylosuccinate synthetase/0.451
1z3cSA8mRNA cap guanine-N7 methyltransferase2.1.1.560.451
2owuSAHDiphthine synthase/0.451
2p2xSAHDiphthine synthase/0.451
2p6iSAHDiphthine synthase/0.451
3oibFDAPutative acyl-CoA dehydrogenase/0.451
3ovaAPCCCA-adding enzyme2.7.7.720.451
4bfzZVZPantothenate kinase2.7.1.330.451
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.451
4jxrACOAcetyltransferase/0.451
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.451
5fklTDCTetracycline repressor protein class D/0.451
1cnfFADNitrate reductase [NADH]1.7.1.10.450
1nahNADUDP-glucose 4-epimerase5.1.3.20.450
1wp4NDP3-hydroxyisobutyrate dehydrogenase/0.450
2cftPLPPyridoxal phosphate phosphatase/0.450
2dv4SAHDiphthine synthase/0.450
2ea2F77Methionine aminopeptidase 2/0.450
2ehlSAHDiphthine synthase/0.450
2ek2SAHDiphthine synthase/0.450
2gdzNAD15-hydroxyprostaglandin dehydrogenase [NAD(+)]1.1.1.1410.450
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.450
2rdn1PL1-deoxypentalenic acid 11-beta-hydroxylase1.14.11.350.450
2wvlGDDMannosyl-3-phosphogylcerate synthase/0.450
3apwDP0Alpha-1-acid glycoprotein 2/0.450
3cosNADAlcohol dehydrogenase 41.1.1.10.450
3e4aQIXInsulin-degrading enzyme3.4.24.560.450
3eheNADUDP-glucose 4-epimerase (GalE-1)/0.450
3eksCY9Actin-5C/0.450
3hk1B64Fatty acid-binding protein, adipocyte/0.450
3uu114BAnthranilate phosphoribosyltransferase/0.450
4ambDUDPutative glycosyl transferase/0.450
4cukNAID-lactate dehydrogenase/0.450
4eo3FMNBacterioferritin comigratory protein/NADH dehydrogenase/0.450
4gdy0X1Kynurenine/alpha-aminoadipate aminotransferase, mitochondrial2.6.1.390.450
4l4xNDPAmphI/0.450
4m4922YL-lactate dehydrogenase A chain1.1.1.270.450
4uymVOR14-alpha sterol demethylase Cyp51B/0.450
4yagNAIC alpha-dehydrogenase/0.450
5dozNDPJamJ/0.450
1h63FMNPentaerythritol tetranitrate reductase/0.449
1kvsUPGUDP-glucose 4-epimerase5.1.3.20.449
1mp0NADAlcohol dehydrogenase class-31.1.1.10.449
1nzdUPGDNA beta-glucosyltransferase/0.449
1vl8NAPOxidoreductase, short chain dehydrogenase/reductase family/0.449
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.449
2c94TSF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.449
2dknNAI3-alpha-hydroxysteroid dehydrogenase/0.449
2eh5SAHDiphthine synthase/0.449
2pj4414Carboxypeptidase B/0.449
2xveFADPutative flavin-containing monooxygenase/0.449
2zu9GDPMannosyl-3-phosphoglycerate synthase2.4.1.2170.449
3hatGLY_VAL_ARG_RNGProthrombin3.4.21.50.449
3udn09BBeta-secretase 13.4.23.460.449
4eu9COASuccinyl-CoA:acetate CoA-transferase/0.449
4gz612VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.449
4tqgNDPPutative dTDP-d-glucose 4 6-dehydratase/0.449
4yxm2BADNA integrity scanning protein DisA/0.449
1ikgREXD-alanyl-D-alanine carboxypeptidase3.4.16.40.448
1k4mNADNicotinate-nucleotide adenylyltransferase2.7.7.180.448
1wxjIPLTryptophan synthase alpha chain/0.448
1zdwFLVPrenyltransferase/0.448
2ejzSAHDiphthine synthase/0.448
2ou2ACOHistone acetyltransferase KAT5/0.448
2p6dSAHDiphthine synthase/0.448
2y6o1N1Ephrin type-A receptor 42.7.10.10.448
3il1B5DGlutamate receptor 2/0.448
3kb6NADD-lactate dehydrogenase/0.448
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.448
3s87ADPRibonucleoside-diphosphate reductase large chain 11.17.4.10.448
4b144XBGlycylpeptide N-tetradecanoyltransferase/0.448
4fw8NAI3-oxoacyl-(Acyl-carrier-protein) reductase/0.448
4jicFMNGTN Reductase/0.448
4ke01R8Beta-secretase 13.4.23.460.448
4opiFDAConserved Archaeal protein/0.448
4qxr1YEStimulator of interferon genes protein/0.448
4qysPLRTryptophan synthase beta chain 24.2.1.200.448
5c1d12VUDP-N-acetylglucosamine--peptide N-acetylglucosaminyltransferase 110 kDa subunit/0.448
5cflC2EStimulator of interferon genes protein/0.448
5jdzSAHMethyl transferase/0.448
1fcbFMNCytochrome b2, mitochondrial1.1.2.30.447
1ipeNDPTropinone reductase 21.1.1.2360.447
1nupNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.447
1rp0AHZThiamine thiazole synthase, chloroplastic/0.447
1rt9IMHPurine nucleoside phosphorylase2.4.2.10.447
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.447
2c31TZDOxalyl-CoA decarboxylase4.1.1.80.447
2d81RB3Poly(3-hydroxybutyrate) depolymerase/0.447
2eh4SAHDiphthine synthase/0.447
2ekaSAHDiphthine synthase/0.447
2el3SAHDiphthine synthase/0.447
2huxSAHDiphthine synthase/0.447
2qrqS13Glycogen phosphorylase, muscle form2.4.1.10.447
2vutNADNitrogen metabolite repression protein nmrA/0.447
2wi4ZZ4Heat shock protein HSP 90-alpha/0.447
2y99NADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.447
2zs9ADPPantothenate kinase2.7.1.330.447
3drcMTXDihydrofolate reductase1.5.1.30.447
3dy85GPHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3f63GTXGlutathione transferase GST1-4/0.447
3intGDUUDP-galactopyranose mutase5.4.99.90.447
3lq4TDPPyruvate dehydrogenase E1 component1.2.4.10.447
3qgi33FGenome polyprotein2.7.7.480.447
3sfy3FYUncharacterized protein/0.447
4auxXTCTetracycline repressor protein class D/0.447
4dx7DM2Multidrug efflux pump subunit AcrB/0.447
4gllNADUDP-glucuronic acid decarboxylase 14.1.1.350.447
4gv4MEJPoly [ADP-ribose] polymerase 32.4.2.300.447
4im01FVSerine/threonine-protein kinase TBK12.7.11.10.447
4l7j1W2Beta-secretase 13.4.23.460.447
4lxa1YSBeta-secretase 13.4.23.460.447
4q4kFMNUncharacterized protein/0.447
5kwvANPPantothenate synthetase/0.447
1kbo340NAD(P)H dehydrogenase [quinone] 11.6.5.20.446
1n2bPAFPantothenate synthetase6.3.2.10.446
1p9wANPType II secretion system protein E/0.446
1ps9MDE2,4-dienoyl-CoA reductase1.3.1.340.446
1tojHCIAspartate aminotransferase2.6.1.10.446
1z41FMNNADPH dehydrogenase/0.446
2a5hSAML-lysine 2,3-aminomutase5.4.3.20.446
2a5kAZPReplicase polyprotein 1ab3.4.220.446
2e17SAHDiphthine synthase/0.446
2e7rSAHDiphthine synthase/0.446
2q1tNADPutative nucleotide sugar epimerase/ dehydratase/0.446
2xrlDXTTetracycline repressor protein class D/0.446
2zhq27UProthrombin3.4.21.50.446
3hyg099A disintegrin and metalloproteinase with thrombospondin motifs 53.4.240.446
3nytULPUDP-2-acetamido-2-deoxy-3-oxo-D-glucuronate aminotransferase2.6.1.980.446
3s2v3HUGlutamate receptor ionotropic, kainate 1/0.446
4fam0SZAldo-keto reductase family 1 member C3/0.446
4h1e10JBeta-secretase 13.4.23.460.446
4hbgNDP3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.446
4lol1YEStimulator of interferon genes protein/0.446
4m6jNDPDihydrofolate reductase1.5.1.30.446
1b2lNDCAlcohol dehydrogenase1.1.1.10.445
1bmfANPATP synthase subunit alpha, mitochondrial/0.445
1bmfANPATP synthase subunit beta, mitochondrial3.6.3.140.445
1gg5FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.445
1gssLEEGlutathione S-transferase P2.5.1.180.445
1gzuNMNNicotinamide/nicotinic acid mononucleotide adenylyltransferase 12.7.7.10.445
1i59ANPChemotaxis protein CheA2.7.13.30.445
1qvuPRLHTH-type transcriptional regulator QacR/0.445
1rywEPUUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.445
1sb1165Prothrombin3.4.21.50.445
1tqf32PBeta-secretase 13.4.23.460.445
2c29NAPDihydroflavonol 4-reductase/0.445
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.445
2eudGCQRibonucleoside-diphosphate reductase large chain 11.17.4.10.445
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.445
2nvkFADThioredoxin reductase 1, mitochondrial1.8.1.90.445
2qn7HBZGlycogen phosphorylase, muscle form2.4.1.10.445
2rgjFADFlavin-containing monooxygenase/0.445
3b7dCNIGlutamate receptor 2/0.445
3bhiNAPCarbonyl reductase [NADPH] 11.1.1.1840.445
3ckqUPGGlucosyl-3-phosphoglycerate synthase2.4.1.2660.445
3dm5GDPSignal recognition particle 54 kDa protein/0.445
3ingNDPHomoserine dehydrogenase related protein/0.445
3iqiASN_GLU_ASN_ILECysteine synthase2.5.1.470.445
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.445
3p5pA3CTaxadiene synthase4.2.3.170.445
3sptUD1Bifunctional protein GlmU/0.445
3ukfGDUUDP-galactopyranose mutase/0.445
4acuQN7Beta-secretase 13.4.23.460.445
4b68NAPL-ornithine N(5)-monooxygenase/0.445
4bqh9VUUDP-N-acetylglucosamine pyrophosphorylase, putative/0.445
4f9gC2EStimulator of interferon genes protein/0.445
4gsuDWZL,D-transpeptidase 22.3.20.445
4tvj09LPoly [ADP-ribose] polymerase 22.4.2.300.445
5adhAPRAlcohol dehydrogenase E chain1.1.1.10.445
1dgmADNAdenosine kinase2.7.1.200.444
1e6wNAD3-hydroxyacyl-CoA dehydrogenase type-21.1.1.350.444
1g0rTHMGlucose-1-phosphate thymidylyltransferase/0.444
1g6kNADGlucose 1-dehydrogenase1.1.1.470.444
1grgFADGlutathione reductase, mitochondrial1.8.1.70.444
1j49NADD-lactate dehydrogenase1.1.1.280.444
2e08SAHDiphthine synthase/0.444
2eeqSAHDiphthine synthase/0.444
2hr8SAHDiphthine synthase/0.444
2ifaFMNUncharacterized protein/0.444
2iviACWIsopenicillin N synthase1.21.3.10.444
2jbsFMNp-hydroxyphenylacetate 3-hydroxylase, oxygenase component/0.444
2p5cSAHDiphthine synthase/0.444
3autNAIGlucose 1-dehydrogenase 41.1.1.470.444
3jv7NADSecondary alcohol dehydrogenase/0.444
3jzdNADMaleylacetate reductase/0.444
3pchCHBProtocatechuate 3,4-dioxygenase beta chain1.13.11.30.444
3rpeFADPutative modulator of drug activity/0.444
3tr05GPGuanylate kinase/0.444
4acxS8ZBeta-secretase 13.4.23.460.444
4b1e6T6Beta-secretase 13.4.23.460.444
4bkqNAIEnoyl-[acyl-carrier-protein] reductase [NADH]/0.444
4cdmFO1Deoxyribodipyrimidine photolyase/0.444
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.444
4s1iPLPPyridoxal kinase, putative/0.444
4ttcFMNIodotyrosine deiodinase 1/0.444
4yaiNAIC alpha-dehydrogenase/0.444
4yal2AMNADPH--cytochrome P450 reductase/0.444
1cdoNADAlcohol dehydrogenase 11.1.1.10.443
1cq8PY6Aspartate aminotransferase2.6.1.10.443
1dmwHBIPhenylalanine-4-hydroxylase1.14.16.10.443
1fapRAPPeptidyl-prolyl cis-trans isomerase FKBP1A5.2.1.80.443
1fapRAPSerine/threonine-protein kinase mTOR2.7.11.10.443
1g0nNDPTetrahydroxynaphthalene reductase1.1.1.2520.443
1nffNAD3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.443
1nhhANPDNA mismatch repair protein MutL/0.443
1nuqNXXNicotinamide/nicotinic acid mononucleotide adenylyltransferase 3/0.443
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.443
2a1tFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.443
2e4nSAHDiphthine synthase/0.443
2e8uIPEGeranylgeranyl pyrophosphate synthase/0.443
2fzwNADAlcohol dehydrogenase class-31.1.1.10.443
2ikuLIYRenin3.4.23.150.443
2pb2PLPAcetylornithine/succinyldiaminopimelate aminotransferase2.6.1.110.443
2zvbSAHPrecorrin-3 C17-methyltransferase/0.443
3gvhNADMalate dehydrogenase/0.443
3hdqGDUUDP-galactopyranose mutase/0.443
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.443
3pm1ETHTH-type transcriptional regulator QacR/0.443
3qlrNDPDihydrofolate reductase1.5.1.30.443
3w1tWRODihydroorotate dehydrogenase (fumarate)1.3.98.10.443
4b3aTACTetracycline repressor protein class D/0.443
4b4vL34Bifunctional protein FolD/0.443
4h3i10VBeta-secretase 13.4.23.460.443
4kp5E1FCarbonic anhydrase 124.2.1.10.443
4oqyNDP(S)-imine reductase/0.443
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.443
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.443
1culFOKAdenylate cyclase type 2/0.442
1culFOKAdenylate cyclase type 5/0.442
1dr3HBIDihydrofolate reductase1.5.1.30.442
1drhNAPDihydrofolate reductase1.5.1.30.442
1dxyNADD-2-hydroxyisocaproate dehydrogenase1.1.10.442
1f8wFADNADH peroxidase1.11.1.10.442
1p3dUMAUDP-N-acetylmuramate--L-alanine ligase6.3.2.80.442
1p5rCOAFormyl-CoA:oxalate CoA-transferase/0.442
1udyFADMedium-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.70.442
2bb3SAHCobalamin biosynthesis precorrin-6Y methylase (CbiE)/0.442
2ed5SAHDiphthine synthase/0.442
2irzI02Beta-secretase 13.4.23.460.442
2p9dSAHDiphthine synthase/0.442
2ph835ABeta-secretase 13.4.23.460.442
2q4bNAPUncharacterized protein At5g02240/0.442
2xejOKDGlutamate carboxypeptidase 23.4.17.210.442
2zatNAPDehydrogenase/reductase SDR family member 41.1.1.1840.442
3b6zCO7Enoyl reductase LovC10.442
3bloQEIQueuine tRNA-ribosyltransferase2.4.2.290.442
3cow52HPantothenate synthetase6.3.2.10.442
3gncQQQGlutaryl-CoA dehydrogenase/0.442
3iocA5DPantothenate synthetase6.3.2.10.442
3lm8VIBThiamine pyrophosphokinase2.7.6.20.442
3sxpNADADP-L-glycero-D-mannoheptose-6-epimerase/0.442
3udj092Beta-secretase 13.4.23.460.442
4bekXK0Beta-secretase 13.4.23.460.442
4cr8NADN-acylmannosamine 1-dehydrogenase1.1.1.2330.442
4eb5PLPCysteine desulfurase IscS 2/0.442
4fco0U4Beta-secretase 13.4.23.460.442
4gv08MEPoly [ADP-ribose] polymerase 32.4.2.300.442
4h12SAHHistone-lysine N-methyltransferase SETD22.1.1.430.442
4kgnSAHtRNA (cytidine(34)-2'-O)-methyltransferase/0.442
4kh0ATPAspartate carbamoyltransferase regulatory chain {ECO:0000256|HAMAP-Rule:MF_00002}/0.442
4l7h1W1Beta-secretase 13.4.23.460.442
4qxp1YEStimulator of interferon genes protein/0.442
4u7wNDPMxaA/0.442
4u8oFDAUDP-galactopyranose mutase/0.442
4xq6FMNDihydroorotate dehydrogenase (quinone)/0.442
4yau2AMNADPH--cytochrome P450 reductase/0.442
1c3x8IGPurine nucleoside phosphorylase2.4.2.10.441
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.441
1d0lBLGMembrane-bound lytic murein transglycosylase B4.2.2.n10.441
1gsnFADGlutathione reductase, mitochondrial1.8.1.70.441
2i65NADADP-ribosyl cyclase/cyclic ADP-ribose hydrolase 13.2.2.60.441
2p83MR0Beta-secretase 13.4.23.460.441
2qlnF59Glycogen phosphorylase, muscle form2.4.1.10.441
2wzmNA7Uncharacterized oxidoreductase MSMEG_2407/MSMEI_2346/0.441
2xjeU5PCytosolic purine 5'-nucleotidase3.1.3.50.441
2z95NDPGDP-mannose 4,6-dehydratase/0.441
3eu5GBOProtein farnesyltransferase subunit beta2.5.1.580.441
3hgoFMN12-oxophytodienoate reductase 31.3.1.420.441
3iahNAPPutative oxoacyl-(Acyl carrier protein) reductase/0.441
3k5c0BIBeta-secretase 13.4.23.460.441
3v2uATPProtein GAL3/0.441
3veu0GOBeta-secretase 13.4.23.460.441
4c13UMLUDP-N-acetylmuramoyl-L-alanyl-D-glutamate--L-lysine ligase/0.441
4c4oNADSADH/0.441
4driRAPSerine/threonine-protein kinase mTOR2.7.11.10.441
4driRAPPeptidyl-prolyl cis-trans isomerase FKBP55.2.1.80.441
4e2yJHZMethyltransferase/0.441
4fduIHSPutative multiple inositol polyphosphate histidine phosphatase 1/0.441
4gh5NADShort-chain dehydrogenase/reductase SDR/0.441
4tlxFDAKtzI/0.441
4wx1FDAUDP-galactopyranose mutase/0.441
5ahsFADAcyl-CoA dehydrogenase/0.441
1h73ANPHomoserine kinase2.7.1.390.440
1hncGDNGlutathione S-transferase Mu 22.5.1.180.440
1i2bNADUDP-sulfoquinovose synthase, chloroplastic3.13.1.10.440
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.440
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.440
1n2iPAJPantothenate synthetase6.3.2.10.440
1n75ATPGlutamate--tRNA ligase6.1.1.170.440
1w6jR71Lanosterol synthase5.4.99.70.440
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.440
2freFMNNAD(P)H-flavin oxidoreductase/0.440
2hizLIJBeta-secretase 13.4.23.460.440
2pb4SAHDiphthine synthase/0.440
2wb2FADRE11660p/0.440
2x93X93Angiotensin-converting enzyme3.4.15.10.440
2xpuTDCTetracycline repressor protein class D/0.440
3b03VNRIsopentenyl-diphosphate delta-isomerase/0.440
3b05FNRIsopentenyl-diphosphate delta-isomerase/0.440
3bazNAPHydroxyphenylpyruvate reductase1.1.1.2370.440
3bw2FMNPutative 2-nitropropane dioxygenase/0.440
3cvuFADRE11660p/0.440
3gnvXNZGenome polyprotein2.7.7.480.440
3h6vNS6Glutamate receptor 2/0.440
3ijoB4DGlutamate receptor 2/0.440
3ijrNADOxidoreductase, short chain dehydrogenase/reductase family/0.440
3ru9NADUDP-N-acetylglucosamine 4-epimerase/0.440
3zksWZVBeta-secretase 23.4.23.450.440
4b1rITCTetracycline repressor protein class D/0.440
4la1FADThioredoxin glutathione reductase/0.440
4nh82LCHeat shock protein HSP 90-alpha/0.440
4o7uTHFThymidylate synthase/0.440
4q71FADBifunctional protein PutA/0.440
4qak2AMRNA 2',3'-cyclic phosphodiesterase/0.440
4rn615UProthrombin3.4.21.50.440
4uocNCNCinA-like protein/0.440
4xfjANPArgininosuccinate synthase/0.440
4zlaBESCytosol aminopeptidase3.4.11.10.440
5kjcNAJAlcohol dehydrogenase E chain1.1.1.10.440