sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Sites are compared using Shaper.
For more information, please see the following publication:
Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 2yog | 74X | Thymidylate kinase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Site Similarity |
Align |
|---|---|---|---|---|---|
| 2yog | 74X | Thymidylate kinase | / | 1.000 | |
| 1y2c | 3DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.537 | |
| 1rkp | IBM | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.536 | |
| 3hmv | HBT | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.535 | |
| 5e9e | ANP | Myosin heavy chain kinase A | 2.7.11.7 | 0.534 | |
| 3lmh | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.532 | |
| 2ouu | 35G | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.531 | |
| 3bjc | WAN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.529 | |
| 1q9m | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.519 | |
| 3itu | IBM | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.518 | |
| 2yoh | WMJ | Thymidylate kinase | / | 0.517 | |
| 3o57 | ZG2 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.511 | |
| 4mvh | 2F5 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.511 | |
| 2our | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.509 | |
| 3qpn | PFK | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.509 | |
| 4fcd | 0T6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.509 | |
| 4uog | YYY | Nucleoside diphosphate kinase | / | 0.509 | |
| 4zme | ADN | Myosin heavy chain kinase A | 2.7.11.7 | 0.509 | |
| 1y2k | 7DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.508 | |
| 3cr7 | PPS | Adenylyl-sulfate kinase | 2.7.1.25 | 0.508 | |
| 4fcb | 0T7 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.508 | |
| 1mkd | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.507 | |
| 4a0s | CO8 | Octenoyl-CoA reductase/carboxylase | / | 0.507 | |
| 4zs4 | ATP | Myosin heavy chain kinase A | 2.7.11.7 | 0.507 | |
| 2fm0 | M98 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.506 | |
| 3qpo | PFR | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.504 | |
| 1xng | DND | NH(3)-dependent NAD(+) synthetase | 6.3.1.5 | 0.503 | |
| 3w5e | NVW | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.503 | |
| 4x5j | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.503 | |
| 2o8h | 227 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.502 | |
| 2vd0 | D27 | Hematopoietic prostaglandin D synthase | / | 0.502 | |
| 3pdt | ADP | Myosin heavy chain kinase A | 2.7.11.7 | 0.502 | |
| 4hf4 | 15H | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.501 | |
| 1xom | CIO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.500 | |
| 3lla | ACP | Myosin heavy chain kinase A | 2.7.11.7 | 0.500 | |
| 1kmy | BPY | Biphenyl-2,3-diol 1,2-dioxygenase | 1.13.11.39 | 0.499 | |
| 2tpl | HPP | Tyrosine phenol-lyase | 4.1.99.2 | 0.498 | |
| 4j7h | TRH | PCZA361.3 | / | 0.498 | |
| 2ovy | PFJ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.497 | |
| 4oew | 5IO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.496 | |
| 1u1d | 181 | Uridine phosphorylase | 2.4.2.3 | 0.495 | |
| 2fm5 | M99 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.495 | |
| 3g4g | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.495 | |
| 4heu | 15J | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.495 | |
| 3o56 | ZG1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.494 | |
| 4da6 | GA2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.494 | |
| 1zkn | IBM | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.493 | |
| 2ovv | PFH | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.493 | |
| 3d3p | 20A | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.493 | |
| 2ouy | CMP | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.492 | |
| 3rth | RTH | Beta-secretase 1 | 3.4.23.46 | 0.492 | |
| 4kp6 | 1S1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.492 | |
| 3sn7 | 540 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.491 | |
| 3ufl | 508 | Beta-secretase 1 | 3.4.23.46 | 0.491 | |
| 4bfv | ZVV | Pantothenate kinase | 2.7.1.33 | 0.491 | |
| 3g58 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.490 | |
| 1lco | PPY | Cytochrome b2, mitochondrial | 1.1.2.3 | 0.489 | |
| 5kf2 | COA | Predicted acetyltransferase | / | 0.489 | |
| 1y2d | 4DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.488 | |
| 1y5w | NEZ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.488 | |
| 2w98 | P1Z | Prostaglandin reductase 2 | 1.3.1.48 | 0.488 | |
| 4dvq | 1CA | Cytochrome P450 11B2, mitochondrial | 1.14.15.4 | 0.488 | |
| 1al7 | HST | Peroxisomal (S)-2-hydroxy-acid oxidase | 1.1.3.15 | 0.487 | |
| 1oyn | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.486 | |
| 3ngu | ADP | Nucleoside diphosphate kinase | / | 0.486 | |
| 3rvi | RVI | Beta-secretase 1 | 3.4.23.46 | 0.486 | |
| 3g45 | 988 | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.485 | |
| 3g4l | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.485 | |
| 2z3u | CRR | Cytochrome P450 | / | 0.484 | |
| 1be4 | PCG | Nucleoside diphosphate kinase A 2 | 2.7.4.6 | 0.483 | |
| 1rp4 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.483 | |
| 4ia0 | 5BB | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.483 | |
| 4oex | 5EO | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.483 | |
| 1qiq | ACC | Isopenicillin N synthase | 1.21.3.1 | 0.482 | |
| 1xon | PIL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.482 | |
| 4ajd | F04 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.482 | |
| 4i9z | 5BA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.482 | |
| 1y2e | 5DE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.480 | |
| 3af3 | GCP | Pantothenate kinase | 2.7.1.33 | 0.480 | |
| 3arv | SAU | Chitinase A | / | 0.480 | |
| 5ckw | ANP | Uncharacterized protein | / | 0.479 | |
| 1soj | IBM | cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 3.1.4.17 | 0.478 | |
| 3g4i | D71 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.478 | |
| 4uof | DAT | Nucleoside diphosphate kinase | / | 0.478 | |
| 4uoh | ADP | Nucleoside diphosphate kinase | / | 0.478 | |
| 2h44 | 7CA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.477 | |
| 4ajf | F03 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 4bft | ZVT | Pantothenate kinase | 2.7.1.33 | 0.477 | |
| 4jib | 1L6 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.477 | |
| 4muw | 2F4 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.477 | |
| 1r8q | AFB | Cytohesin-2 | / | 0.476 | |
| 1r8q | AFB | ADP-ribosylation factor 1 | / | 0.476 | |
| 2wsa | 646 | Glycylpeptide N-tetradecanoyltransferase | / | 0.476 | |
| 1bq1 | CB3 | Thymidylate synthase | / | 0.475 | |
| 1dpm | EBP | Parathion hydrolase | 3.1.8.1 | 0.475 | |
| 4ajg | F07 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.475 | |
| 4hr2 | ADP | Nucleoside diphosphate kinase | / | 0.475 | |
| 4ttj | FMC | Purine nucleoside phosphorylase DeoD-type | / | 0.475 | |
| 1qjf | ACS | Isopenicillin N synthase | 1.21.3.1 | 0.474 | |
| 3f3y | 4OA | Bile salt sulfotransferase | 2.8.2.14 | 0.474 | |
| 3k4s | 0MO | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.474 | |
| 3v94 | WYQ | Phosphodiesterase | / | 0.474 | |
| 4ag7 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.474 | |
| 4g2w | NI0 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.474 | |
| 1u1g | BBB | Uridine phosphorylase | 2.4.2.3 | 0.473 | |
| 3gg2 | UGA | Sugar dehydrogenase, UDP-glucose/GDP-mannose dehydrogenase family | / | 0.473 | |
| 1n71 | COA | Aac(6')-Ii protein | / | 0.472 | |
| 1rq1 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.472 | |
| 1y2b | DEE | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.472 | |
| 4dpd | DHF | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.472 | |
| 4ea0 | 651 | Dehydrosqualene synthase | / | 0.472 | |
| 4ea1 | 3RX | Dehydrosqualene synthase | / | 0.472 | |
| 1blz | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.471 | |
| 3dga | RJ1 | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.471 | |
| 1ih7 | GMP | DNA-directed DNA polymerase | / | 0.470 | |
| 2cvz | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.470 | |
| 4z87 | GDP | Inosine-5'-monophosphate dehydrogenase | / | 0.470 | |
| 1rvv | INI | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.469 | |
| 3lmi | ATP | Myosin heavy chain kinase A | 2.7.11.7 | 0.469 | |
| 3qpp | PFW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.469 | |
| 4ovi | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.469 | |
| 2q15 | 3MR | Beta-secretase 1 | 3.4.23.46 | 0.468 | |
| 2wpw | ACO | Orf14 | / | 0.468 | |
| 3szf | DCQ | Sulfide-quinone reductase | / | 0.468 | |
| 5doz | NDP | JamJ | / | 0.468 | |
| 1clq | GDP | DNA-directed DNA polymerase | / | 0.467 | |
| 2zse | ACP | Pantothenate kinase | 2.7.1.33 | 0.467 | |
| 3sl8 | JN7 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.467 | |
| 4cjx | 9L9 | C-1-tetrahydrofolate synthase, cytoplasmic, putative | / | 0.467 | |
| 4llk | MEW | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.467 | |
| 1xor | ZAR | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.466 | |
| 2o6h | INI | 6,7-dimethyl-8-ribityllumazine synthase 1 | 2.5.1.78 | 0.466 | |
| 2pl0 | STI | Tyrosine-protein kinase Lck | 2.7.10.2 | 0.466 | |
| 3glm | COO | Glutaconyl-CoA decarboxylase alpha subunit | / | 0.466 | |
| 4dan | 2FA | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.466 | |
| 4kw5 | 1W6 | Decaprenylphosphoryl-beta-D-ribose oxidase | / | 0.466 | |
| 5kf9 | ACO | Predicted acetyltransferase | / | 0.466 | |
| 1pt8 | ACO | Formyl-CoA:oxalate CoA-transferase | / | 0.465 | |
| 1sjw | NGV | Nogalonic acid methyl ester cyclase | / | 0.465 | |
| 1tbb | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.465 | |
| 1xp8 | AGS | Protein RecA | / | 0.465 | |
| 2jc6 | QPP | Calcium/calmodulin-dependent protein kinase type 1D | 2.7.11.17 | 0.465 | |
| 2jj2 | ANP | ATP synthase subunit beta, mitochondrial | 3.6.3.14 | 0.465 | |
| 2wey | EV1 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.465 | |
| 3a1l | 2CC | Cytochrome P450 | / | 0.465 | |
| 3wd9 | QPC | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.465 | |
| 4b13 | X25 | Glycylpeptide N-tetradecanoyltransferase | / | 0.465 | |
| 4ffr | ATP | Uncharacterized protein | / | 0.465 | |
| 4irn | FAD | AnaB | / | 0.465 | |
| 4j7g | TRH | PCZA361.3 | / | 0.465 | |
| 4xoq | F42 | Coenzyme F420:L-glutamate ligase | / | 0.465 | |
| 1iah | ADP | Transient receptor potential cation channel subfamily M member 7 | 2.7.11.1 | 0.464 | |
| 1rd4 | L08 | Integrin alpha-L | / | 0.464 | |
| 1ro9 | 8BR | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.464 | |
| 1wp4 | NDP | 3-hydroxyisobutyrate dehydrogenase | / | 0.464 | |
| 2bfm | TOP | Pteridine reductase 1 | 1.5.1.33 | 0.464 | |
| 2zcq | B65 | Dehydrosqualene synthase | / | 0.464 | |
| 3dy8 | 5GP | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.464 | |
| 3neg | PYV | Abscisic acid receptor PYL1 | / | 0.464 | |
| 3ptz | UDX | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.464 | |
| 4da7 | AC2 | Purine nucleoside phosphorylase DeoD-type | 2.4.2.1 | 0.464 | |
| 4ddl | 0JQ | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.464 | |
| 4fkx | CDP | Nucleoside diphosphate kinase | / | 0.464 | |
| 4lwa | Q13 | Nitric oxide synthase oxygenase | 1.14.13.165 | 0.464 | |
| 1y56 | FMN | Uncharacterized protein | / | 0.463 | |
| 1y56 | FMN | 382aa long hypothetical sarcosine oxidase | / | 0.463 | |
| 1u1c | BAU | Uridine phosphorylase | 2.4.2.3 | 0.462 | |
| 1udt | VIA | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 1uho | VDN | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.462 | |
| 4tzk | 641 | Enoyl-[acyl-carrier-protein] reductase [NADH] | 1.3.1.9 | 0.462 | |
| 5a2w | AGS | Mitochondrial poly(A) polymerase | / | 0.462 | |
| 5d0r | B1T | Adenylate cyclase type 10 | / | 0.462 | |
| 1ghe | ACO | Acetyltransferase | 2.3.1 | 0.461 | |
| 1hb1 | OCV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 1oc1 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2fs4 | PZ1 | Renin | 3.4.23.15 | 0.461 | |
| 2ji9 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.461 | |
| 2vbp | VB1 | Isopenicillin N synthase | 1.21.3.1 | 0.461 | |
| 2y4m | GDX | Uncharacterized protein | / | 0.461 | |
| 2yne | YNE | Glycylpeptide N-tetradecanoyltransferase | / | 0.461 | |
| 3m31 | FAD | Endoplasmic oxidoreductin-1 | 1.8.4 | 0.461 | |
| 3t0k | DCQ | Sulfide-quinone reductase | / | 0.461 | |
| 3x0c | 5GP | Phosphatidylinositol 5-phosphate 4-kinase type-2 beta | 2.7.1.149 | 0.461 | |
| 4bkj | STI | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.461 | |
| 4phl | PIL | Phosphodiesterase | / | 0.461 | |
| 1zkl | IBM | High affinity cAMP-specific 3',5'-cyclic phosphodiesterase 7A | 3.1.4.53 | 0.460 | |
| 2c9e | PID | Peridinin-chlorophyll a protein, high-salt form | / | 0.460 | |
| 2cn0 | F25 | Prothrombin | 3.4.21.5 | 0.460 | |
| 2e99 | B08 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.460 | |
| 3tdk | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.460 | |
| 4blc | NDP | Catalase | 1.11.1.6 | 0.460 | |
| 4cth | RDF | Neprilysin | / | 0.460 | |
| 4kyk | IMN | Lactoylglutathione lyase | 4.4.1.5 | 0.460 | |
| 1e90 | MYC | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.459 | |
| 3b82 | NAD | Exotoxin A | 2.4.2.36 | 0.459 | |
| 3is9 | AC7 | Gag-Pol polyprotein | 2.7.7.49 | 0.459 | |
| 4e32 | DWN | Methyltransferase | / | 0.459 | |
| 4h2i | A12 | 5'-nucleotidase | 3.1.3.5 | 0.459 | |
| 5iqf | GDP | Bifunctional AAC/APH | 2.3.1 | 0.459 | |
| 1hb3 | SCV | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 1xoq | ROF | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.458 | |
| 2jbs | FMN | p-hydroxyphenylacetate 3-hydroxylase, oxygenase component | / | 0.458 | |
| 2y6f | M9F | Isopenicillin N synthase | 1.21.3.1 | 0.458 | |
| 3nrr | D16 | Bifunctional dihydrofolate reductase-thymidylate synthase | / | 0.458 | |
| 3rtn | RTN | Beta-secretase 1 | 3.4.23.46 | 0.458 | |
| 3tpt | ADP | Serine/threonine-protein kinase toxin HipA | / | 0.458 | |
| 4edf | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.458 | |
| 4g2y | NI5 | cGMP-specific 3',5'-cyclic phosphodiesterase | / | 0.458 | |
| 4hkf | ACO | Alpha-tubulin N-acetyltransferase 1 | / | 0.458 | |
| 5cc9 | DDF | Dihydrofolate reductase | 1.5.1.3 | 0.458 | |
| 1obn | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.457 | |
| 1s36 | CEI | Obelin | / | 0.457 | |
| 1u70 | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 2g27 | 4LG | Renin | 3.4.23.15 | 0.457 | |
| 2jcs | TTP | Deoxynucleoside kinase | / | 0.457 | |
| 3eon | 341 | Glutaryl-CoA dehydrogenase | / | 0.457 | |
| 3ghv | GHC | Dihydrofolate reductase | 1.5.1.3 | 0.457 | |
| 3hu2 | AGS | Transitional endoplasmic reticulum ATPase | 3.6.4.6 | 0.457 | |
| 3jwc | EKB | Dihydrofolate reductase | / | 0.457 | |
| 3n5x | XFK | Nitric oxide synthase, brain | 1.14.13.39 | 0.457 | |
| 3pg3 | DG7 | Mitogen-activated protein kinase 14 | / | 0.457 | |
| 3sl6 | JN8 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.457 | |
| 4iyg | 1HU | Strictosidine synthase | 4.3.3.2 | 0.457 | |
| 4mvc | CDC | Choline-phosphate cytidylyltransferase A | / | 0.457 | |
| 5kf9 | COA | Predicted acetyltransferase | / | 0.457 | |
| 1hfq | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.456 | |
| 1xf0 | ASD | Aldo-keto reductase family 1 member C3 | / | 0.456 | |
| 2gzl | 2AA | 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase | 4.6.1.12 | 0.456 | |
| 2ji6 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.456 | |
| 2w5a | ADP | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.456 | |
| 2wgs | 1AZ | Glutamine synthetase | 6.3.1.2 | 0.456 | |
| 3n87 | N87 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.456 | |
| 4bl5 | GFB | GDP-L-fucose synthase | 1.1.1.271 | 0.456 | |
| 4f6v | ZYM | Dehydrosqualene synthase | / | 0.456 | |
| 4kf1 | HT5 | Aryldialkylphosphatase | 3.1.8.1 | 0.456 | |
| 4y6u | UPG | Glucosyl-3-phosphoglycerate synthase | 2.4.1.266 | 0.456 | |
| 4zas | TYD | CalS13 | / | 0.456 | |
| 5iw5 | NMN | NADH pyrophosphatase | / | 0.456 | |
| 1dgb | NDP | Catalase | 1.11.1.6 | 0.455 | |
| 1wsv | THH | Aminomethyltransferase, mitochondrial | / | 0.455 | |
| 2cjf | RP4 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.455 | |
| 2pun | ACP | Methylthioribose kinase | 2.7.1.100 | 0.455 | |
| 3ept | FDA | Putative FAD-monooxygenase | / | 0.455 | |
| 3iak | EV1 | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.455 | |
| 4h1e | 10J | Beta-secretase 1 | 3.4.23.46 | 0.455 | |
| 4li6 | 1XO | Tankyrase-1 | 2.4.2.30 | 0.455 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.455 | |
| 4zu4 | 4TG | WxcM-like protein | / | 0.455 | |
| 1i12 | ACO | Glucosamine 6-phosphate N-acetyltransferase | / | 0.454 | |
| 1qk3 | 5GP | Hypoxanthine-guanine-xanthine phosphoribosyltransferase | 2.4.2.22 | 0.454 | |
| 2d06 | EST | Sulfotransferase 1A1 | 2.8.2.1 | 0.454 | |
| 2vn1 | FK5 | Peptidylprolyl isomerase | / | 0.454 | |
| 3dok | GWJ | Pol protein | / | 0.454 | |
| 3ghw | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3gi2 | GHW | Dihydrofolate reductase | 1.5.1.3 | 0.454 | |
| 3k1w | BFX | Renin | 3.4.23.15 | 0.454 | |
| 4i6h | 1C8 | Serine/threonine-protein kinase PLK2 | 2.7.11.21 | 0.454 | |
| 5ark | UMP | Ribonuclease 4 | 3.1.27 | 0.454 | |
| 5f54 | TMP | Single-stranded-DNA-specific exonuclease | / | 0.454 | |
| 1e92 | HBI | Pteridine reductase 1 | 1.5.1.33 | 0.453 | |
| 1zdw | FLV | Prenyltransferase | / | 0.453 | |
| 2aaz | CB3 | Thymidylate synthase | 2.1.1.45 | 0.453 | |
| 2r7n | ADP | 5-formaminoimidazole-4-carboxamide-1-(beta)-D-ribofuranosyl 5'-monophosphate synthetase | / | 0.453 | |
| 2wo7 | ASV | Isopenicillin N synthase | 1.21.3.1 | 0.453 | |
| 2xkc | 4VQ | Serine/threonine-protein kinase Nek2 | 2.7.11.1 | 0.453 | |
| 3ggs | 2FD | Purine nucleoside phosphorylase | 2.4.2.1 | 0.453 | |
| 3lal | KRV | Gag-Pol polyprotein | 2.7.7.49 | 0.453 | |
| 3njo | PYV | Abscisic acid receptor PYR1 | / | 0.453 | |
| 3qh2 | 3NM | Thiazole tautomerase | / | 0.453 | |
| 3tda | PN0 | Cytochrome P450 2D6 | / | 0.453 | |
| 3u9f | CLM | Chloramphenicol acetyltransferase | 2.3.1.28 | 0.453 | |
| 4crz | ACO | PanD regulatory factor | / | 0.453 | |
| 4lsj | LSJ | Glucocorticoid receptor | / | 0.453 | |
| 4nt3 | ZAW | Lactoperoxidase | 1.11.1.7 | 0.453 | |
| 5kf1 | ACO | Predicted acetyltransferase | / | 0.453 | |
| 2ycx | P32 | Beta-1 adrenergic receptor | / | 0.453 | |
| 1e26 | GPB | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 1eno | NAD | Enoyl-[acyl-carrier-protein] reductase [NADH], chloroplastic | 1.3.1.9 | 0.452 | |
| 1wkl | ATP | Nucleoside diphosphate kinase | / | 0.452 | |
| 2kce | D16 | Thymidylate synthase | / | 0.452 | |
| 2nmt | MIM | Glycylpeptide N-tetradecanoyltransferase | 2.3.1.97 | 0.452 | |
| 2y60 | M8F | Isopenicillin N synthase | 1.21.3.1 | 0.452 | |
| 3n0h | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.452 | |
| 3n5w | XFJ | Nitric oxide synthase, brain | 1.14.13.39 | 0.452 | |
| 3nwl | NDP | Catalase | 1.11.1.6 | 0.452 | |
| 4a32 | 2CD | Glycylpeptide N-tetradecanoyltransferase | / | 0.452 | |
| 4bjb | P34 | Tankyrase-2 | 2.4.2.30 | 0.452 | |
| 4c1i | EH9 | cGMP-dependent 3',5'-cyclic phosphodiesterase | 3.1.4.17 | 0.452 | |
| 4j6d | TES | Cytochrome P450 monooxygenase | / | 0.452 | |
| 4ybn | FAD | Flavin-nucleotide-binding protein | / | 0.452 | |
| 5d6l | CAU | Beta-2 adrenergic receptor | / | 0.452 | |
| 1kyv | RBF | 6,7-dimethyl-8-ribityllumazine synthase | 2.5.1.78 | 0.451 | |
| 1oj4 | CDM | 4-diphosphocytidyl-2-C-methyl-D-erythritol kinase | 2.7.1.148 | 0.451 | |
| 2owb | 626 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.451 | |
| 2rds | 1PL | 1-deoxypentalenic acid 11-beta-hydroxylase | 1.14.11.35 | 0.451 | |
| 3dyn | PCG | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.451 | |
| 3uay | ADN | Purine nucleoside phosphorylase DeoD-type | / | 0.451 | |
| 4ag9 | COA | Glucosamine 6-phosphate N-acetyltransferase | / | 0.451 | |
| 4ajm | 3A6 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.451 | |
| 4at4 | T6E | BDNF/NT-3 growth factors receptor | 2.7.10.1 | 0.451 | |
| 4m6k | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.451 | |
| 4oma | LCS | Methionine gamma-lyase | / | 0.451 | |
| 4qa2 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.451 | |
| 4wbd | ADP | Putative cysteine ligase BshC | / | 0.451 | |
| 1dia | L24 | C-1-tetrahydrofolate synthase, cytoplasmic | 1.5.1.5 | 0.450 | |
| 1ho5 | ADN | Protein UshA | 3.1.3.5 | 0.450 | |
| 1jra | FAD | FAD-linked sulfhydryl oxidase ERV2 | 1.8.3.2 | 0.450 | |
| 1k9s | FM1 | Purine nucleoside phosphorylase DeoD-type | / | 0.450 | |
| 1n4p | CYS_VAL_ILE_LEU_GER | Geranylgeranyl transferase type-1 subunit beta | 2.5.1.59 | 0.450 | |
| 1pqc | 444 | Oxysterols receptor LXR-beta | / | 0.450 | |
| 1w06 | W05 | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 1waj | 5GP | DNA-directed DNA polymerase | / | 0.450 | |
| 2bfp | H4B | Pteridine reductase 1 | 1.5.1.33 | 0.450 | |
| 2ivi | ACW | Isopenicillin N synthase | 1.21.3.1 | 0.450 | |
| 4c2z | 646 | Glycylpeptide N-tetradecanoyltransferase 1 | / | 0.450 | |
| 4ddr | MMV | Dihydrofolate reductase | 1.5.1.3 | 0.450 | |
| 4fri | DWA | Beta-secretase 1 | 3.4.23.46 | 0.450 | |
| 4gtv | 7TR | Geranylgeranyl transferase type-2 subunit beta | 2.5.1.60 | 0.450 | |
| 4x7z | ZM3 | Mycinamicin III 3''-O-methyltransferase | 2.1.1.237 | 0.450 | |
| 1uzw | CDH | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2bjs | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.449 | |
| 2ix5 | FAD | Acyl-coenzyme A oxidase 4, peroxisomal | 1.3.3.6 | 0.449 | |
| 2obx | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | 2.5.1.78 | 0.449 | |
| 2y0d | UGA | UDP-glucose dehydrogenase | / | 0.449 | |
| 3ba6 | AN2 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.449 | |
| 3fco | IIG | Corticosteroid 11-beta-dehydrogenase isozyme 1 | 1.1.1.146 | 0.449 | |
| 3gc4 | AAQ | Queuine tRNA-ribosyltransferase | 2.4.2.29 | 0.449 | |
| 3gie | ACP | Sensor histidine kinase DesK | 2.7.13.3 | 0.449 | |
| 3hav | ATP | Aminoglycoside phosphotransferase | / | 0.449 | |
| 3irx | UDR | Gag-Pol polyprotein | 2.7.7.49 | 0.449 | |
| 4bj9 | UHB | Tankyrase-2 | 2.4.2.30 | 0.449 | |
| 4c77 | N01 | Phenylacetone monooxygenase | 1.14.13.92 | 0.449 | |
| 4dkb | DUN | Deoxyuridine triphosphatase, putative | / | 0.449 | |
| 4feu | 537 | Aminoglycoside 3'-phosphotransferase AphA1-IAB | / | 0.449 | |
| 4fqf | NAD | Aldehyde dehydrogenase, mitochondrial | 1.2.1.3 | 0.449 | |
| 4gb9 | 0WR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.449 | |
| 4nbj | D3Y | D-tyrosyl-tRNA(Tyr) deacylase | / | 0.449 | |
| 4pl9 | ADP | Ethylene receptor 1 | / | 0.449 | |
| 5agk | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.449 | |
| 1daj | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 1dgf | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1klk | PMD | Dihydrofolate reductase | 1.5.1.3 | 0.448 | |
| 2jb4 | A14 | Isopenicillin N synthase | 1.21.3.1 | 0.448 | |
| 2vqj | TFG | Histone deacetylase 4 | 3.5.1.98 | 0.448 | |
| 2zrz | FNR | Isopentenyl-diphosphate delta-isomerase | / | 0.448 | |
| 3hdy | GDU | UDP-galactopyranose mutase | / | 0.448 | |
| 3jsi | WTC | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.448 | |
| 3lak | KR1 | Gag-Pol polyprotein | 2.7.7.49 | 0.448 | |
| 4b12 | C23 | Glycylpeptide N-tetradecanoyltransferase | / | 0.448 | |
| 4fk3 | 325 | Serine/threonine-protein kinase B-raf | 2.7.11.1 | 0.448 | |
| 4gqk | ADP | Actin cross-linking toxin VgrG1 | / | 0.448 | |
| 4nc3 | ERM | 5-hydroxytryptamine receptor 2B | / | 0.448 | |
| 4ohw | ATP | Protein clpf-1 | / | 0.448 | |
| 4qa0 | SHH | Histone deacetylase 8 | 3.5.1.98 | 0.448 | |
| 7cat | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 8cat | NDP | Catalase | 1.11.1.6 | 0.448 | |
| 1bk0 | ACV | Isopenicillin N synthase | 1.21.3.1 | 0.447 | |
| 1gt5 | BZQ | Odorant-binding protein | / | 0.447 | |
| 1jol | FFO | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1mdl | RMN | Mandelate racemase | / | 0.447 | |
| 1t3z | CAO | Formyl-CoA:oxalate CoA-transferase | / | 0.447 | |
| 1uae | UD1 | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.447 | |
| 1vi0 | DCC | Fatty acid metabolism regulator protein | / | 0.447 | |
| 1yho | TRR | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 1zpr | CB3 | Thymidylate synthase | / | 0.447 | |
| 1zyd | ATP | eIF-2-alpha kinase GCN2 | / | 0.447 | |
| 2i4t | UA2 | Purine nucleoside phosphorylase, putative | / | 0.447 | |
| 2y4k | GDP | Uncharacterized protein | / | 0.447 | |
| 3qar | QAR | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.447 | |
| 3zlm | ANP | Adenosine monophosphate-protein transferase NmFic | 2.7.7.n1 | 0.447 | |
| 4ao4 | PLK | Beta-transaminase | / | 0.447 | |
| 4b14 | 4XB | Glycylpeptide N-tetradecanoyltransferase | / | 0.447 | |
| 4g2l | 0WL | High affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A | / | 0.447 | |
| 4g8z | TOP | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4h3g | 10Q | Beta-secretase 1 | 3.4.23.46 | 0.447 | |
| 4kfj | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.447 | |
| 4l09 | 1UR | Tankyrase-2 | 2.4.2.30 | 0.447 | |
| 4lb2 | DM5 | Serum albumin | / | 0.447 | |
| 4tl7 | ATP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.447 | |
| 5bp9 | SAH | Putative methyltransferase protein | / | 0.447 | |
| 5kf8 | ACO | Predicted acetyltransferase | / | 0.447 | |
| 1pke | 2FD | Purine nucleoside phosphorylase DeoD-type | / | 0.446 | |
| 1s3u | TQD | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 2ejz | SAH | Diphthine synthase | / | 0.446 | |
| 2gpj | FAD | Siderophore-interacting protein | / | 0.446 | |
| 2oat | PFM | Ornithine aminotransferase, mitochondrial | 2.6.1.13 | 0.446 | |
| 2rl5 | 2RL | Vascular endothelial growth factor receptor 2 | 2.7.10.1 | 0.446 | |
| 2ycn | P61 | Tyrosine phenol-lyase | 4.1.99.2 | 0.446 | |
| 3dya | PZL | Gag-Pol polyprotein | 2.7.7.49 | 0.446 | |
| 3g4k | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4D | 3.1.4.53 | 0.446 | |
| 3n39 | FMN | Protein NrdI | / | 0.446 | |
| 3zu0 | A12 | NAD 5'-nucleotidase | 3.1.3.5 | 0.446 | |
| 4ffl | ADP | Uncharacterized protein | / | 0.446 | |
| 4fzb | 0VJ | Probable flavin-dependent thymidylate synthase | 2.1.1.148 | 0.446 | |
| 4iah | 1DX | Alr2278 protein | / | 0.446 | |
| 4keb | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.446 | |
| 5ab6 | CAA | Nonspecific lipid-transfer protein, putative | / | 0.446 | |
| 5agl | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.446 | |
| 5hi6 | MTX | Dihydrofolate reductase | / | 0.446 | |
| 1r35 | H4B | Nitric oxide synthase, inducible | 1.14.13.39 | 0.445 | |
| 1ysi | N3B | Bcl-2-like protein 1 | / | 0.445 | |
| 2bo7 | GDP | Mannosylglycerate synthase | / | 0.445 | |
| 2pdl | TOL | Aldose reductase | 1.1.1.21 | 0.445 | |
| 2yof | 74W | Thymidylate kinase | / | 0.445 | |
| 3dau | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.445 | |
| 3fow | IMH | Purine nucleoside phosphorylase | / | 0.445 | |
| 3n0y | APC | Adenylate cyclase 2 | / | 0.445 | |
| 3ndj | JHZ | Methyltransferase | / | 0.445 | |
| 3udq | 09E | Beta-secretase 1 | 3.4.23.46 | 0.445 | |
| 4b8z | GDP | GDP-L-fucose synthase | 1.1.1.271 | 0.445 | |
| 4bbx | LKF | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.445 | |
| 4e2x | TYD | Methyltransferase | / | 0.445 | |
| 4j6b | PLO | Cytochrome P450 monooxygenase | / | 0.445 | |
| 4qi9 | MTX | Dihydrofolate reductase | / | 0.445 | |
| 1drb | MTX | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 1ro6 | ROL | cAMP-specific 3',5'-cyclic phosphodiesterase 4B | 3.1.4.53 | 0.444 | |
| 1trg | CB3 | Thymidylate synthase | / | 0.444 | |
| 1z6t | ADP | Apoptotic protease-activating factor 1 | / | 0.444 | |
| 2j07 | HDF | Deoxyribodipyrimidine photo-lyase | 4.1.99.3 | 0.444 | |
| 2qw8 | NAP | Eugenol synthase 1 | 1.1.1.318 | 0.444 | |
| 2x0e | TYD | WsaF | / | 0.444 | |
| 3ar6 | TG1 | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.444 | |
| 3hz6 | ADP | Xylulokinase | / | 0.444 | |
| 3ntz | 3TZ | Dihydrofolate reductase | 1.5.1.3 | 0.444 | |
| 3p0f | BAU | Uridine phosphorylase 2 | 2.4.2.3 | 0.444 | |
| 3tfj | THG | Dimethylsulfonioproprionate demethylase DmdA | 2.1.1.269 | 0.444 | |
| 4a2a | ATP | Cell division protein FtsA | / | 0.444 | |
| 5hbr | COA | Acyl-CoA synthetase (NDP forming) | / | 0.444 | |
| 1c7o | PPG | Hemolysin | / | 0.443 | |
| 1lnm | DTX | Bilin-binding protein | / | 0.443 | |
| 1nec | FMN | Oxygen-insensitive NAD(P)H nitroreductase | 1 | 0.443 | |
| 1tdu | CB3 | Thymidylate synthase | / | 0.443 | |
| 1wpg | ADP | Sarcoplasmic/endoplasmic reticulum calcium ATPase 1 | 3.6.3.8 | 0.443 | |
| 2fto | CB3 | Thymidylate synthase | / | 0.443 | |
| 2z7g | EH9 | Adenosine deaminase | 3.5.4.4 | 0.443 | |
| 3akl | ADP | Serine/threonine-protein kinase CtkA | 2.7.11.1 | 0.443 | |
| 3h3t | 16H | Collagen type IV alpha-3-binding protein | / | 0.443 | |
| 3i58 | 7NA | 2,7-dihydroxy-5-methyl-1-naphthoate 7-O-methyltransferase | / | 0.443 | |
| 3lfc | Z86 | Mitogen-activated protein kinase 14 | / | 0.443 | |
| 3uq6 | ADN | Putative adenosine kinase | / | 0.443 | |
| 4a4o | 664 | Serine/threonine-protein kinase PLK1 | 2.7.11.21 | 0.443 | |
| 4b4v | L34 | Bifunctional protein FolD | / | 0.443 | |
| 4c1m | NIH | Myeloperoxidase | 1.11.2.2 | 0.443 | |
| 4cs0 | ACO | PanD regulatory factor | / | 0.443 | |
| 4el9 | AFE | Ribosomal protein S6 kinase alpha-3 | 2.7.11.1 | 0.443 | |
| 4equ | G6I | Serine/threonine-protein kinase 10 | 2.7.11.1 | 0.443 | |
| 4h3j | 10W | Beta-secretase 1 | 3.4.23.46 | 0.443 | |
| 4tla | ADP | Circadian clock protein kinase KaiC | 2.7.11.1 | 0.443 | |
| 5ab7 | MLC | Nonspecific lipid-transfer protein, putative | / | 0.443 | |
| 1dqa | COA | 3-hydroxy-3-methylglutaryl-coenzyme A reductase | 1.1.1.34 | 0.442 | |
| 1fp1 | HCC | Isoliquiritigenin 2'-O-methyltransferase | / | 0.442 | |
| 1hfr | MOT | Dihydrofolate reductase | 1.5.1.3 | 0.442 | |
| 1l0c | COT | Serotonin N-acetyltransferase | / | 0.442 | |
| 1q1g | MTI | Purine nucleoside phosphorylase | / | 0.442 | |
| 1t13 | INI | 6,7-dimethyl-8-ribityllumazine synthase 2 | / | 0.442 | |
| 1tys | DHF | Thymidylate synthase | / | 0.442 | |
| 2bra | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.442 | |
| 2hvd | ADP | Nucleoside diphosphate kinase A | 2.7.4.6 | 0.442 | |
| 2jfz | 003 | Glutamate racemase | / | 0.442 | |
| 2wks | CB6 | 3-dehydroquinate dehydratase | 4.2.1.10 | 0.442 | |
| 2ydd | 2AM | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.442 | |
| 3uax | NOS | Purine nucleoside phosphorylase DeoD-type | / | 0.442 | |
| 3uft | HW7 | Nitric oxide synthase, brain | 1.14.13.39 | 0.442 | |
| 3zky | WT4 | Isopenicillin N synthase | 1.21.3.1 | 0.442 | |
| 4d04 | NAP | Phenylacetone monooxygenase | 1.14.13.92 | 0.442 | |
| 4jvl | EST | Estrogen sulfotransferase | 2.8.2.4 | 0.442 | |
| 3uzc | T4E | Adenosine receptor A2a | / | 0.442 | |
| 1crb | RTL | Retinol-binding protein 1 | / | 0.441 | |
| 1mvs | DTM | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 1vhn | FMN | tRNA-dihydrouridine synthase | / | 0.441 | |
| 2d3a | ADP | Glutamine synthetase root isozyme 3 | 6.3.1.2 | 0.441 | |
| 2e1z | B4P | Propionate kinase | / | 0.441 | |
| 2fzj | DH3 | Dihydrofolate reductase | 1.5.1.3 | 0.441 | |
| 2gvc | FAD | Thiol-specific monooxygenase | 1.14.13 | 0.441 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.441 | |
| 2ij7 | TPF | Mycocyclosin synthase | 1.14.21.9 | 0.441 | |
| 2q3e | UPG | UDP-glucose 6-dehydrogenase | 1.1.1.22 | 0.441 | |
| 2ydb | NAP | 2',3'-cyclic-nucleotide 3'-phosphodiesterase | 3.1.4.37 | 0.441 | |
| 3aq0 | ISY | Solanesyl diphosphate synthase 3, chloroplastic/mitochondrial | 2.5.1.85 | 0.441 | |
| 3gy9 | COA | GCN5-related N-acetyltransferase | / | 0.441 | |
| 3srz | UPG | Toxin A | / | 0.441 | |
| 3tpr | 5HA | Beta-secretase 1 | 3.4.23.46 | 0.441 | |
| 4ckr | DI1 | Epithelial discoidin domain-containing receptor 1 | 2.7.10.1 | 0.441 | |
| 4e0u | 0MV | Cyclic dipeptide N-prenyltransferase | / | 0.441 | |
| 4fhk | 0U0 | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4fvz | H4B | Nitric oxide synthase, brain | 1.14.13.39 | 0.441 | |
| 4hvb | 19P | Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform | 2.7.1.153 | 0.441 | |
| 4ky4 | 04J | Bifunctional dihydrofolate reductase-thymidylate synthase | 1.5.1.3 | 0.441 | |
| 4wx2 | F6F | Tryptophan synthase alpha chain | / | 0.441 | |
| 4wx2 | F6F | Tryptophan synthase beta chain | 4.2.1.20 | 0.441 | |
| 1b87 | ACO | Aac(6')-Ii protein | / | 0.440 | |
| 1juj | LYA | Thymidylate synthase | 2.1.1.45 | 0.440 | |
| 1lhw | ESM | Sex hormone-binding globulin | / | 0.440 | |
| 1nue | GDP | Nucleoside diphosphate kinase B | 2.7.4.6 | 0.440 | |
| 2c42 | TPP | Pyruvate synthase | / | 0.440 | |
| 2e9a | B28 | Ditrans,polycis-undecaprenyl-diphosphate synthase ((2E,6E)-farnesyl-diphosphate specific) | 2.5.1.31 | 0.440 | |
| 2g26 | 3LG | Renin | 3.4.23.15 | 0.440 | |
| 2i8c | ADP | D-alanine--D-alanine ligase | / | 0.440 | |
| 2ivp | ATP | tRNA N6-adenosine threonylcarbamoyltransferase | / | 0.440 | |
| 2ji7 | ADP | Oxalyl-CoA decarboxylase | 4.1.1.8 | 0.440 | |
| 2lfo | GCH | Fatty acid-binding protein, liver | / | 0.440 | |
| 2yvw | EPU | UDP-N-acetylglucosamine 1-carboxyvinyltransferase | / | 0.440 | |
| 2zit | NAD | Exotoxin A | 2.4.2.36 | 0.440 | |
| 3b78 | NAD | Exotoxin A | 2.4.2.36 | 0.440 | |
| 3dej | RXC | Caspase-3 | 3.4.22.56 | 0.440 | |
| 3jsx | CC2 | NAD(P)H dehydrogenase [quinone] 1 | 1.6.5.2 | 0.440 | |
| 3lfe | Z84 | Mitogen-activated protein kinase 14 | / | 0.440 | |
| 3p8i | FMN | Pentaerythritol tetranitrate reductase | / | 0.440 | |
| 3p99 | LNP | Lanosterol 14-alpha-demethylase | / | 0.440 | |
| 3p9t | TCL | Repressor | / | 0.440 | |
| 3tvx | PNX | cAMP-specific 3',5'-cyclic phosphodiesterase 4A | 3.1.4.53 | 0.440 | |
| 3wi2 | P98 | cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A | 3.1.4.17 | 0.440 | |
| 4br0 | AU1 | Ectonucleoside triphosphate diphosphohydrolase 2 | / | 0.440 | |
| 4edz | 0O5 | Hematopoietic prostaglandin D synthase | / | 0.440 | |
| 4ffm | ADP | Uncharacterized protein | / | 0.440 | |
| 4g8c | C6L | Alpha/beta hydrolase fold protein | / | 0.440 | |
| 4h3f | 10O | Beta-secretase 1 | 3.4.23.46 | 0.440 | |
| 4ixd | 1HV | Integrin alpha-L | / | 0.440 | |
| 4to1 | DCP | Deoxynucleoside triphosphate triphosphohydrolase SAMHD1 | 3.1.5 | 0.440 | |
| 4x5g | FOL | Dihydrofolate reductase | 1.5.1.3 | 0.440 | |
| 5bn3 | ADP | V-type ATP synthase alpha chain | / | 0.440 | |
| 5bn3 | ADP | NEQ263 | / | 0.440 |