Logo scPDB

sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

Logo CNRS Logo Unistra
Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
2pr5FMNBlue-light photoreceptor

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
2pr5FMNBlue-light photoreceptor/1.000
3t50FMNBlue-light-activated histidine kinase2.7.13.30.613
4wujFMNGlycoside hydrolase family 15, cellulose signaling associated protein envoy/0.612
3ue6FMNAureochrome1/0.594
4hhdFMNPhototropin-12.7.11.10.592
5djtFMNNPH1-2/0.592
4eeuFMNPhototropin-22.7.11.10.590
1n9lFMNPutative blue light receptor/0.589
2z6dFMNPhototropin-22.7.11.10.589
3p7nFMNLight-activated DNA-binding protein EL222/0.587
3is2FADVivid PAS protein VVD/0.579
4eetFMNPhototropin-22.7.11.10.573
5djuFMNNPH1-2/0.567
1n9nFMNPutative blue light receptor/0.565
2z6cFMNPhototropin-12.7.11.10.561
2pdtFADVivid PAS protein VVD/0.560
3d72FADVivid PAS protein VVD/0.552
4r38RBFBlue-light-activated histidine kinase 22.7.13.30.549
4eerFMNPhototropin-22.7.11.10.547
2pd7FADVivid PAS protein VVD/0.544
4hj6FMNLOV protein/0.539
4eesFMNPhototropin-22.7.11.10.534
2pd8FADVivid PAS protein VVD/0.531
4hiaFMNLOV protein/0.526
4kukRBFPutative blue-light photoreceptor/0.526
5j4eFMNSensory box protein/0.523
4eepFMNPhototropin-22.7.11.10.521
4hj4FMNLOV protein/0.519
3dv3MEKDual specificity mitogen-activated protein kinase kinase 12.7.12.20.509
3sw1FMNSensory box protein/0.508
2ch6ADPN-acetyl-D-glucosamine kinase2.7.1.590.504
4lxhC1EAlpha/beta hydrolase fold/0.504
5dkkFMNPredicted protein/0.503
1iolESTEstradiol 17-beta-dehydrogenase 11.1.1.620.498
4a4vYFDPeroxisome proliferator-activated receptor gamma/0.498
5j3wFMNSensory box protein/0.498
2mwgFMNBlue-light photoreceptor/0.497
4hj3FMNLOV protein/0.495
4xumIMNPeroxisome proliferator-activated receptor gamma/0.490
4kuoRBFPutative blue-light photoreceptor/0.489
5efwFMNNPH1-1/0.488
1xddAAYIntegrin alpha-L/0.487
1pnvTYDdTDP-epi-vancosaminyltransferase2.4.1.3110.486
2q61SF1Peroxisome proliferator-activated receptor gamma/0.486
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.486
1u8vFAD4-hydroxybutyryl-CoA dehydratase/vinylacetyl-CoA-Delta-isomerase/0.485
2ebaFADPutative glutaryl-CoA dehydrogenase/0.485
2v1aFMNNPH1-1/0.484
1g28FMNPHY3/0.483
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.483
3wv9FEGHmd co-occurring protein HcgE/0.482
4hgl0YOCasein kinase I isoform gamma-32.7.11.10.482
4jazSTLPeroxisome proliferator-activated receptor gamma/0.482
1hygNAPL-2-hydroxycarboxylate dehydrogenase (NAD(P)(+))/0.481
2gjlFMNNitronate monooxygenase1.13.12.160.481
3d8vUD1Bifunctional protein GlmU/0.481
3f3sNADLambda-crystallin homolog/0.481
3lqfNADGalactitol dehydrogenase/0.481
2ejvNADL-threonine 3-dehydrogenase/0.480
4ji91M3Tyrosine-protein kinase JAK2/0.480
4yswFADXanthine dehydrogenase/oxidase/0.480
2ql6ADPNicotinamide riboside kinase 1/0.479
3oibFDAPutative acyl-CoA dehydrogenase/0.478
4c58824Cyclin-G-associated kinase2.7.11.10.478
4hnbFMNLOV protein/0.478
1llzFMNFerredoxin-dependent glutamate synthase 21.4.7.10.477
2q59240Peroxisome proliferator-activated receptor gamma/0.477
2v0uFMNNPH1-1/0.477
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.477
3dheANDEstradiol 17-beta-dehydrogenase 11.1.1.620.476
4dfl0K0Tyrosine-protein kinase SYK2.7.10.20.476
4eakATP5'-AMP-activated protein kinase subunit gamma-1/0.476
3ibqATPPyridoxal kinase/0.475
4i22IREEpidermal growth factor receptor2.7.10.10.475
2c59NADGDP-mannose 3,5-epimerase5.1.3.180.474
4mq12C3Dual specificity tyrosine-phosphorylation-regulated kinase 1A2.7.12.10.474
3vvpBNUUncharacterized protein/0.473
4oj4DIFPeroxisome proliferator-activated receptor gamma/0.473
2hwrDRDPeroxisome proliferator-activated receptor gamma/0.472
1rfuADPPyridoxal kinase2.7.1.350.471
2p4yC03Peroxisome proliferator-activated receptor gamma/0.471
2p54735Peroxisome proliferator-activated receptor alpha/0.471
2vigFADShort-chain specific acyl-CoA dehydrogenase, mitochondrial1.3.8.10.471
2yyiFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.471
4a84DXCMajor pollen allergen Bet v 1-A/0.471
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.471
1dhrNADDihydropteridine reductase1.5.1.340.470
1l8qADPChromosomal replication initiator protein DnaA/0.470
2j4z626Aurora kinase A2.7.11.10.470
3a20FMNFMN-binding protein/0.470
3d84NDPDihydrofolate reductase1.5.1.30.470
3ssnMVIMycinamicin VI 2''-O-methyltransferase/0.470
3mqe416Prostaglandin G/H synthase 21.14.99.10.469
3n7uNADFormate dehydrogenase, chloroplastic/mitochondrial/0.469
4zohFADPutative oxidoreductase FAD-binding subunit/0.469
1drhNAPDihydrofolate reductase1.5.1.30.468
1k7l544Peroxisome proliferator-activated receptor alpha/0.468
2e08SAHDiphthine synthase/0.468
3h06VBPGlutamate receptor 2/0.468
3umpATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.468
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.468
4ocvANPAminoglycoside phosphotransferase/0.468
1vcfFMNIsopentenyl-diphosphate delta-isomerase/0.467
2hunNAD336aa long hypothetical dTDP-glucose 4,6-dehydratase/0.467
3hhu819Heat shock protein HSP 90-alpha/0.467
3w2eNADNADH-cytochrome b5 reductase 31.6.2.20.467
1sxjADPReplication factor C subunit 5/0.466
3mdmFJZCholesterol 24-hydroxylase/0.466
3t1tGDPProbable gliding protein mglA/0.466
2cf6NAPCinnamyl alcohol dehydrogenase 51.1.1.1950.465
3nbvANPKetohexokinase/0.465
3sp6IL2Peroxisome proliferator-activated receptor alpha/0.465
3uylTYDProbable NDP-rhamnosyltransferase/0.465
4enhFVXCholesterol 24-hydroxylase/0.465
2freFMNNAD(P)H-flavin oxidoreductase/0.464
2hydADPPutative multidrug export ATP-binding/permease protein SAV18663.6.30.464
3a4oSTUTyrosine-protein kinase Lyn2.7.10.20.464
3qa2XNAKetohexokinase/0.464
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.464
4gk3L87Ephrin type-A receptor 32.7.10.10.464
4prxADPDNA gyrase subunit B/0.464
3kduNKSPeroxisome proliferator-activated receptor alpha/0.463
4dxd9PCCell division protein FtsZ/0.463
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.463
4i6aHMG3-hydroxy-3-methylglutaryl-coenzyme A reductase1.1.1.880.463
4m6jNDPDihydrofolate reductase1.5.1.30.463
5c8wPCGcGMP-dependent protein kinase 22.7.11.120.463
1jpaANPEphrin type-B receptor 22.7.10.10.462
2d29FADAcyl-CoA dehydrogenase/0.462
2gjnFMNNitronate monooxygenase1.13.12.160.462
2nruT12Interleukin-1 receptor-associated kinase 42.7.11.10.462
3qlrNDPDihydrofolate reductase1.5.1.30.462
4m10ICDProstaglandin G/H synthase 21.14.99.10.462
1g1aNADdTDP-glucose 4,6-dehydratase/0.461
1i58ACPChemotaxis protein CheA2.7.13.30.461
1tj0FADBifunctional protein PutA1.5.5.20.461
3cinNADMyo-inositol-1-phosphate synthase-related protein/0.461
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.461
3frqERYErythromycin resistance repressor protein/0.461
3kb1ADPIron-sulfur cluster carrier protein/0.461
4qecNAPElxO/0.461
4qi4FADCellobiose dehydrogenase/0.461
5cnnANPEpidermal growth factor receptor2.7.10.10.461
2cduFADNADH oxidase/0.460
2npaMMBPeroxisome proliferator-activated receptor alpha/0.460
2y0mACOHistone acetyltransferase KAT8/0.460
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.460
3gobHXXDdmC/0.460
3icsADPCoenzyme A disulfide reductase/0.460
3qqs17CAnthranilate phosphoribosyltransferase/0.460
3ruqADPChaperonin/0.460
3tdvGDPGentamicin resistance protein/0.460
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.460
4oavACP2-5A-dependent ribonuclease3.1.260.460
1kboFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.459
2a87FADThioredoxin reductase1.8.1.90.459
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.459
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.459
2ou5FMNPyridoxamine 5'-phosphate oxidase-related FMN-binding protein/0.459
2yneNHWGlycylpeptide N-tetradecanoyltransferase/0.459
3l63CAMCamphor 5-monooxygenase1.14.15.10.459
3oqfS51Renin3.4.23.150.459
3oqkS52Renin3.4.23.150.459
3vs1VSATyrosine-protein kinase HCK2.7.10.20.459
4fuyEK2Mitogen-activated protein kinase 12.7.11.240.459
4wh2ADPN-acetylhexosamine 1-kinase2.7.1.1620.459
1a2nTETUDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.458
1meiMOAInosine-5'-monophosphate dehydrogenase/0.458
1pn3TYDdTDP-epi-vancosaminyltransferase2.4.1.3110.458
2hckQUETyrosine-protein kinase HCK2.7.10.20.458
2j8zNAPQuinone oxidoreductase PIG310.458
2yfeYFEPeroxisome proliferator-activated receptor gamma/0.458
3gfbNADL-threonine 3-dehydrogenase/0.458
3slkNDPPolyketide synthase extender module 2/0.458
4djaFAD(6-4) photolyase/0.458
4oagADPMitochondrial dynamics protein MID51/0.458
4r8qADPMitotic checkpoint serine/threonine-protein kinase BUB12.7.11.10.458
1ib0NADNADH-cytochrome b5 reductase 31.6.2.20.457
1j7kATPHolliday junction ATP-dependent DNA helicase RuvB/0.457
1sx4ADP60 kDa chaperonin/0.457
2pmoHMDProtein kinase 7/0.457
3c1y2BADNA integrity scanning protein DisA/0.457
3clyACPFibroblast growth factor receptor 2/0.457
3jqpA2PFerredoxin--NADP reductase, apicoplast/0.457
3uozFAD2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase1.14.13.1600.457
4aw3MYVMycinamicin IV hydroxylase/epoxidase/0.457
4bb3KKAIsopenicillin N synthase1.21.3.10.457
5a3bAPRSIR2 family protein/0.457
1bxkNADdTDP-glucose 4,6-dehydratase 2/0.456
1h66FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.456
1mjaCOAHistone acetyltransferase ESA1/0.456
1nptNADGlyceraldehyde-3-phosphate dehydrogenase/0.456
2a94AP0L-lactate dehydrogenase1.1.1.270.456
2bz5AB4Heat shock protein HSP 90-alpha/0.456
2c54NADGDP-mannose 3,5-epimerase5.1.3.180.456
2fsvNADNAD(P) transhydrogenase subunit alpha part 11.6.1.20.456
2phkATPPhosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform2.7.11.190.456
3b6zCO7Enoyl reductase LovC10.456
3hllI45Mitogen-activated protein kinase 14/0.456
3nbwTR4Ketohexokinase/0.456
3opdHIEHeat shock protein 83/0.456
3rucNADUDP-N-acetylglucosamine 4-epimerase/0.456
4ipw1G7Mycocyclosin synthase1.14.21.90.456
4z24FADPutative GMC-type oxidoreductase R13510.456
1bwsNDPGDP-L-fucose synthase/0.455
1h69FADNAD(P)H dehydrogenase [quinone] 11.6.5.20.455
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.455
1oc1ASVIsopenicillin N synthase1.21.3.10.455
1zz2B11Mitogen-activated protein kinase 14/0.455
2rbeNDPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.455
2zdt46CMitogen-activated protein kinase 102.7.11.240.455
3c50ADPRhodopsin kinase/0.455
3drcMTXDihydrofolate reductase1.5.1.30.455
3hx4ANPCalmodulin-domain protein kinase 1/0.455
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.455
3nuuJOZ3-phosphoinositide-dependent protein kinase 12.7.11.10.455
3p3zP3ZPutative cytochrome P450/0.455
3tucFPWTyrosine-protein kinase SYK2.7.10.20.455
3vrzVRZTyrosine-protein kinase HCK2.7.10.20.455
4bidIE8Mitogen-activated protein kinase kinase kinase 52.7.11.250.455
4dpuAGSMevalonate diphosphate decarboxylase/0.455
4g6nEK0Mitogen-activated protein kinase 12.7.11.240.455
4kwi1TJReductase homolog/0.455
4u03GTPCyclic GMP-AMP synthase/0.455
4w9wYDJBMP-2-inducible protein kinase2.7.11.10.455
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.454
1e3eNAIAlcohol dehydrogenase 41.1.1.10.454
1llwFMNFerredoxin-dependent glutamate synthase 21.4.7.10.454
2bkzSBCCyclin-dependent kinase 22.7.11.220.454
2d1cNAPIsocitrate dehydrogenase [NADP]1.1.1.420.454
2ktdPUCProstaglandin-H2 D-isomerase5.3.99.20.454
2zjwREFCasein kinase II subunit alpha2.7.11.10.454
3b9lAZZSerum albumin/0.454
3bxrDRRGag-Pol polyprotein3.4.23.160.454
3d7tSTUTyrosine-protein kinase CSK/0.454
3invNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.454
3w32W32Epidermal growth factor receptor2.7.10.10.454
3zewSTUEphrin type-B receptor 42.7.10.10.454
4ambDUDPutative glycosyl transferase/0.454
4fv7E94Mitogen-activated protein kinase 12.7.11.240.454
4gk2L66Ephrin type-A receptor 32.7.10.10.454
4m83ERYOleandomycin glycosyltransferase2.4.10.454
4udrFAD5-(hydroxymethyl)furfural oxidase/0.454
5a4kFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.454
5hsaFASAlcohol oxidase 11.1.3.130.454
1gqtACPRibokinase/0.453
1yb5NAPQuinone oxidoreductase1.6.5.50.453
2aa0MTPAdenosine kinase2.7.1.200.453
2givACOHistone acetyltransferase KAT8/0.453
2izrBRKCasein kinase I isoform gamma-32.7.11.10.453
2ojtUBAGlutamate receptor ionotropic, kainate 1/0.453
2po7CHDFerrochelatase, mitochondrial4.99.1.10.453
2vkeTACTetracycline repressor protein class D/0.453
2vwqNAPGlucose 1-dehydrogenase/0.453
2xyuQ9GEphrin type-A receptor 42.7.10.10.453
2zdu446Mitogen-activated protein kinase 102.7.11.240.453
2znnS44Peroxisome proliferator-activated receptor alpha/0.453
3ijoB4DGlutamate receptor 2/0.453
3kpkFADSulfide-quinone reductase/0.453
3q92XNBKetohexokinase/0.453
4bcrWY1Peroxisome proliferator-activated receptor alpha/0.453
4c7kNAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.453
4l0qNADAlcohol dehydrogenase class-3/0.453
4paoGSPGuanine nucleotide-binding protein G(i) subunit alpha-1/0.453
4uunNAIL-lactate dehydrogenase/0.453
1i59ANPChemotaxis protein CheA2.7.13.30.452
1lm1FMNFerredoxin-dependent glutamate synthase 21.4.7.10.452
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.452
2cahNDPCatalase1.11.1.60.452
2zb3NDPProstaglandin reductase 21.3.1.480.452
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.452
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.452
3pj8404Cyclin-dependent kinase 22.7.11.220.452
3qlsNDPDihydrofolate reductase1.5.1.30.452
4cukNAID-lactate dehydrogenase/0.452
4fxfATPPyruvate kinase PKM2.7.1.400.452
4jayFADUDP-N-acetylenolpyruvoylglucosamine reductase/0.452
4yr9NADL-threonine 3-dehydrogenase, mitochondrial1.1.1.1030.452
1d4aFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.451
1dr2TAPDihydrofolate reductase1.5.1.30.451
1fnnADPORC1-type DNA replication protein/0.451
2bu2ATP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.451
2dcnADP2-keto-3-deoxy-gluconate kinase/0.451
2qo9ANPEphrin type-A receptor 32.7.10.10.451
2vxoXMPGMP synthase [glutamine-hydrolyzing]6.3.5.20.451
2x7f824TRAF2 and NCK-interacting protein kinase2.7.11.10.451
3cylVITBasic phospholipase A2 homolog piratoxin-2/0.451
3f69XDRSerine/threonine-protein kinase PknB2.7.11.10.451
3fhxPLPPyridoxal kinase2.7.1.350.451
3iaeD7KBenzaldehyde lyase/0.451
3ik6HCZGlutamate receptor 2/0.451
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
3vs2VSBTyrosine-protein kinase HCK2.7.10.20.451
3w4yFADMitochondrial FAD-linked sulfhydryl oxidase ERV11.8.3.20.451
3zw3ZW3Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.451
4idv13VMitogen-activated protein kinase kinase kinase 142.7.11.250.451
4lhtCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.451
4nd3NADLactate dehydrogenase, adjacent gene encodes predicted malate dehydrogenase/0.451
4oaeCLMUncharacterized protein/0.451
4u9aSTUInterleukin-1 receptor-associated kinase 42.7.11.10.451
1bygSTUTyrosine-protein kinase CSK/0.450
1e90MYCPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
1g4tFTPThiamine-phosphate synthase/0.450
1hquHBYGag-Pol polyprotein2.7.7.490.450
1iyzNDPProbable quinone oxidoreductase/0.450
1szmBI4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
1t0lNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.450
1v9aSAHUncharacterized protein/0.450
1y0s331Peroxisome proliferator-activated receptor delta/0.450
2b1pAIZMitogen-activated protein kinase 102.7.11.240.450
2dekSAHDiphthine synthase/0.450
2ev9NAPShikimate dehydrogenase (NADP(+))/0.450
2hqpNDPDihydrofolate reductase1.5.1.30.450
2i4pDRHPeroxisome proliferator-activated receptor gamma/0.450
2qa2FADPolyketide oxygenase CabE/0.450
2y6o1N1Ephrin type-A receptor 42.7.10.10.450
3ad9NADSubunit alpha of sarocosine oxidase/0.450
3d7kD7KBenzaldehyde lyase/0.450
3rdqDTBStreptavidin/0.450
3tscNADUncharacterized protein/0.450
3uhmRFNUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.450
4jb1FADUDP-N-acetylenolpyruvoylglucosamine reductase/0.450
4n6bCOAUncharacterized protein/0.450
4trnNADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.450
5dqrFAD7-hydroxymethyl chlorophyll a reductase, chloroplastic1.17.7.20.450
3sn6P0GBeta-2 adrenergic receptor/0.450
1ee0CAA2-pyrone synthase/0.449
1f0xFADD-lactate dehydrogenase1.1.1.280.449
1lbcCYZGlutamate receptor 2/0.449
1me6IVSPlasmepsin-23.4.23.390.449
1o76CAMCamphor 5-monooxygenase1.14.15.10.449
1r2jFADFkbI/0.449
2xbjXBJSerine/threonine-protein kinase Chk22.7.11.10.449
2y9qANPMitogen-activated protein kinase 12.7.11.240.449
2zbaZBATrichothecene 3-O-acetyltransferase/0.449
3ge1ADPGlycerol kinase/0.449
3h0aD30Peroxisome proliferator-activated receptor gamma/0.449
3i60E86Mitogen-activated protein kinase 12.7.11.240.449
3icsCOACoenzyme A disulfide reductase/0.449
4b8zNAPGDP-L-fucose synthase1.1.1.2710.449
4e5yNDPGDP-L-fucose synthase1.1.1.2710.449
4jlcSU6Serine/threonine-protein kinase TBK12.7.11.10.449
4ki8ADP60 kDa chaperonin/0.449
4lj9ACPChaperone protein ClpB/0.449
4xgxADPFAD:protein FMN transferase/0.449
4xj3GTPCyclic GMP-AMP synthase/0.449
5ajqDB8Serine/threonine-protein kinase 102.7.11.10.449
1u3cFADCryptochrome-1/0.448
1ybmNAPUncharacterized protein At5g02240/0.448
2c0oL2GTyrosine-protein kinase HCK2.7.10.20.448
2excJNKMitogen-activated protein kinase 102.7.11.240.448
2ivuZD6Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.448
2q5g1FAPeroxisome proliferator-activated receptor delta/0.448
2rl2UD1UDP-N-acetylglucosamine 1-carboxyvinyltransferase/0.448
2y05NAPProstaglandin reductase 1/0.448
3cgfJNFMitogen-activated protein kinase 102.7.11.240.448
3dogNNNCyclin-dependent kinase 22.7.11.220.448
3eblGA4Gibberellin receptor GID1/0.448
3g49NAPCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.448
3hk1B64Fatty acid-binding protein, adipocyte/0.448
3sp9IL2Peroxisome proliferator-activated receptor delta/0.448
3zep1NXTyrosine-protein kinase JAK32.7.10.20.448
3zv64HBCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase1.3.1.560.448
4a6eASEAcetylserotonin O-methyltransferase2.1.1.40.448
4f4p0SBTyrosine-protein kinase SYK2.7.10.20.448
4f650S9Fibroblast growth factor receptor 1/0.448
4i0s1B5Tyrosine-protein kinase SYK2.7.10.20.448
4qi5FADCellobiose dehydrogenase/0.448
4wecNADShort chain dehydrogenase/0.448
5c46GSPRas-related protein Rab-11A/0.448
5ctsCMCCitrate synthase, mitochondrial2.3.3.10.448
1b4vFADCholesterol oxidase1.1.3.60.447
1k6pXN3Gag-Pol polyprotein3.4.23.160.447
1m78NDPDihydrofolate reductase1.5.1.30.447
1meiXMPInosine-5'-monophosphate dehydrogenase/0.447
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.447
1qcfPP1Tyrosine-protein kinase HCK2.7.10.20.447
1qorNDPQuinone oxidoreductase 1/0.447
1xkdNAPIsocitrate dehydrogenase [NADP]/0.447
2i5bADPPyridoxine kinase/0.447
2npiATPmRNA cleavage and polyadenylation factor CLP1/0.447
2ouu35GcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
2rkvZBATrichothecene 3-O-acetyltransferase/0.447
2x0rNADMalate dehydrogenase/0.447
2yylFAD4-hydroxyphenylacetate 3-monooxygenase oxygenase component1.14.14.90.447
3a9wNADNDP-sugar epimerase/0.447
3cr3ADPPTS-dependent dihydroxyacetone kinase, ADP-binding subunit DhaL2.70.447
3h6vNS6Glutamate receptor 2/0.447
3hdmMMGSerine/threonine-protein kinase Sgk12.7.11.10.447
4hgs15GCasein kinase I isoform gamma-32.7.11.10.447
4kuhCAA3-hydroxybutyryl-CoA dehydrogenase/0.447
4m9aFDAAcyl-CoA dehydrogenase/0.447
4qi7FADCellobiose dehydrogenase/0.447
4wudANPDNA gyrase subunit B/0.447
1dvrATFAdenylate kinase/0.446
1fm7DFVChalcone--flavonone isomerase 15.5.1.60.446
1qvrANPChaperone protein ClpB/0.446
1rdwLARActin, alpha skeletal muscle/0.446
2dv4SAHDiphthine synthase/0.446
2g5cNADPrephenate dehydrogenase/0.446
2ggsNDPdTDP-4-dehydrorhamnose reductase/0.446
2ivvPP1Proto-oncogene tyrosine-protein kinase receptor Ret2.7.10.10.446
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.446
2y4gTIRTamL/0.446
3k981RCHeat shock protein HSP 90-alpha/0.446
3s1dZIRCytokinin dehydrogenase 11.5.99.120.446
3t3c017Gag-Pol polyprotein3.4.23.160.446
3ttjJBIMitogen-activated protein kinase 102.7.11.240.446
4aoxFADSteroid monooxygenase/0.446
4jib1L6cGMP-dependent 3',5'-cyclic phosphodiesterase3.1.4.170.446
4l6gCNL1,8-cineole 2-endo-monooxygenase1.14.13.1560.446
4m4922YL-lactate dehydrogenase A chain1.1.1.270.446
4xj43ATCyclic GMP-AMP synthase/0.446
5hwsNAP2-dehydropantoate 2-reductase/0.446
1bsvNDPGDP-L-fucose synthase/0.445
1icuFMNOxygen-insensitive NAD(P)H nitroreductase/0.445
1kkq471Peroxisome proliferator-activated receptor alpha/0.445
1nbmADPATP synthase subunit beta, mitochondrial3.6.3.140.445
1nooCAHCamphor 5-monooxygenase1.14.15.10.445
1rbzKT5Trifunctional purine biosynthetic protein adenosine-32.1.2.20.445
1t88CAMCamphor 5-monooxygenase1.14.15.10.445
1w6hTITPlasmepsin-23.4.23.390.445
2bxmIMNSerum albumin/0.445
2cig1DGDihydrofolate reductase1.5.1.30.445
2clqSTUMitogen-activated protein kinase kinase kinase 52.7.11.250.445
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.445
2i4jDRJPeroxisome proliferator-activated receptor gamma/0.445
2igoFADPyranose 2-oxidase/0.445
2jkoBIJFocal adhesion kinase 12.7.10.20.445
2owuSAHDiphthine synthase/0.445
2wa2SAMGenome polyprotein/0.445
2xtzGSPGuanine nucleotide-binding protein alpha-1 subunit/0.445
3gcoVAL_TYR_GLN_PHESerine endoprotease DegS3.4.21.1070.445
3ipq965Oxysterols receptor LXR-alpha/0.445
3irm1CYBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.445
3iw1ASDSteroid C26-monooxygenase1.14.13.1410.445
3jskAHZThiamine thiazole synthase/0.445
3oroAGSSerine/threonine protein kinase/0.445
3rq6APRADP-dependent (S)-NAD(P)H-hydrate dehydratase/0.445
3so9017Pol protein/0.445
4a4wYFBPeroxisome proliferator-activated receptor gamma/0.445
4a8v2ANMajor pollen allergen Bet v 1-J/0.445
4dbzNDPPutative ketoacyl reductase1.3.10.445
4e730NRMitogen-activated protein kinase 82.7.11.240.445
4g170VNCasein kinase I isoform gamma-32.7.11.10.445
4gk4L90Ephrin type-A receptor 32.7.10.10.445
4hwkNAPSepiapterin reductase1.1.1.1530.445
4r20AERCytochrome P450 family 17 polypeptide 2/0.445
4wh3ATPN-acetylhexosamine 1-kinase2.7.1.1620.445
4y93746Tyrosine-protein kinase/0.445
5c03AGSNon-receptor tyrosine-protein kinase TYK22.7.10.20.445
5ez7FADProbable FAD-dependent oxidoreductase PA4991/0.445
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.444
2ekpNAD2-deoxy-D-gluconate 3-dehydrogenase/0.444
2eleSAHDiphthine synthase/0.444
2fgjATPAlpha-hemolysin translocation ATP-binding protein HlyB/0.444
2h2qNAPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.444
2iw84SPCyclin-dependent kinase 22.7.11.220.444
2jcxNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.444
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.444
2nnlNAPDihydroflavonol 4-reductase1.1.1.2190.444
2y3sTIRTamL/0.444
2yy7NADL-threonine dehydrogenase/0.444
3a14NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.444
3aoxEMHALK tyrosine kinase receptor2.7.10.10.444
3cukFADD-amino-acid oxidase1.4.3.30.444
3to6LYS_CMCHistone acetyltransferase ESA1/0.444
4e8yIHAD-beta-D-heptose 7-phosphate kinase/0.444
4jv81M1Retinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.444
4nmdFDABifunctional protein PutA/0.444
4ockANPN-acetylhexosamine 1-kinase2.7.1.1620.444
4q71FADBifunctional protein PutA/0.444
4wsqKSAAP2-associated protein kinase 12.7.11.10.444
4wucANPDNA gyrase subunit B/0.444
4xsvC5PEthanolamine-phosphate cytidylyltransferase2.7.7.140.444
5a3cNADSIR2 family protein/0.444
5e8ySTUTGF-beta receptor type-22.7.11.300.444
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.443
1h73ANPHomoserine kinase2.7.1.390.443
1mj9COAHistone acetyltransferase ESA1/0.443
1nhhANPDNA mismatch repair protein MutL/0.443
1ot7CHCBile acid receptor/0.443
1qpdSTUTyrosine-protein kinase Lck2.7.10.20.443
1s4dSAHUroporphyrinogen-III C-methyltransferase2.1.1.1070.443
1wvgAPRCDP-glucose 4,6-dehydratase4.2.1.450.443
2dteNAIGlucose 1-dehydrogenase related protein/0.443
2h8hH8HProto-oncogene tyrosine-protein kinase Src2.7.10.20.443
3a1nNADNDP-sugar epimerase/0.443
3bbtFMMReceptor tyrosine-protein kinase erbB-42.7.10.10.443
3dd125DGlycogen phosphorylase, liver form2.4.1.10.443
3gdpFAD(R)-mandelonitrile lyase 24.1.2.100.443
3lpbNVBTyrosine-protein kinase JAK2/0.443
3of2NADEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.443
3r83Z14Cyclin-dependent kinase 22.7.11.220.443
3sm2478Putative gag-pro-pol polyprotein/0.443
3tjsD0RCytochrome P450 3A4/0.443
3umvFADDeoxyribodipyrimidine photo-lyase4.1.99.30.443
3unk0BYCyclin-dependent kinase 22.7.11.220.443
3vob9PCCell division protein FtsZ/0.443
3vw6IM6Mitogen-activated protein kinase kinase kinase 52.7.11.250.443
4fv6E57Mitogen-activated protein kinase 12.7.11.240.443
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.443
4k8aK8AFocal adhesion kinase 12.7.10.20.443
4kgmATPUncharacterized protein/0.443
4otpADPSerine/threonine-protein kinase RIO12.7.11.10.443
4yryFADGlutamate synthase, beta subunit/0.443
5c41ACPRibokinase/0.443
5cmsAPRO-acetyl-ADP-ribose deacetylase/0.443
1adfTADAlcohol dehydrogenase E chain1.1.1.10.442
1dxqFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.442
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.442
1nytNAPShikimate dehydrogenase (NADP(+))/0.442
1t87CAMCamphor 5-monooxygenase1.14.15.10.442
1tqf32PBeta-secretase 13.4.23.460.442
1uyhPU0Heat shock protein HSP 90-alpha/0.442
1yrdCAMCamphor 5-monooxygenase1.14.15.10.442
2dfvNADL-threonine 3-dehydrogenase/0.442
2dvlFADAcyl-CoA dehydrogenase/0.442
2nuaCOASuccinate--CoA ligase [ADP-forming] subunit alpha6.2.1.50.442
2pvhP19Casein kinase II subunit alpha2.7.11.10.442
2vn0TDZCytochrome P450 2C8/0.442
2w0jZATSerine/threonine-protein kinase Chk22.7.11.10.442
2xc3RT8Steroid C26-monooxygenase1.14.13.1410.442
3dds26BGlycogen phosphorylase, liver form2.4.1.10.442
3eljGS7Mitogen-activated protein kinase 82.7.11.240.442
3lu8IQXSerum albumin/0.442
3qlfPD5Proto-oncogene tyrosine-protein kinase Src2.7.10.20.442
3uk6ADPRuvB-like 23.6.4.120.442
3v3vMYUMitogen-activated protein kinase 82.7.11.240.442
4a99FADTetX family tetracycline inactivation enzyme/0.442
4c8eC5P2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.442
4fv1EK4Mitogen-activated protein kinase 12.7.11.240.442
4g1wG1WMitogen-activated protein kinase 82.7.11.240.442
4ipeANPTNF receptor-associated protein 1/0.442
4ix5ANPUncharacterized protein/0.442
4ly91YYGlucokinase regulatory protein/0.442
4n6hEJ4Delta-type opioid receptor/0.442
4nr42LKCREB-binding protein/0.442
4q72FADBifunctional protein PutA/0.442
5ej7TD62-succinyl-5-enolpyruvyl-6-hydroxy-3-cyclohexene-1-carboxylate synthase/0.442
1menGARTrifunctional purine biosynthetic protein adenosine-32.1.2.20.441
1unhIXMCyclin-dependent-like kinase 52.7.11.10.441
2dbrNAPGlyoxylate reductase1.1.1.260.441
2dwbANPAurora kinase A2.7.11.10.441
2ek2SAHDiphthine synthase/0.441
2gejGDDPhosphatidyl-myo-inositol mannosyltransferase2.4.1.570.441
2i0zFADNAD(FAD)-utilizing dehydrogenases/0.441
2pobGW4Peroxisome proliferator-activated receptor gamma/0.441
2vcmM11Isopenicillin N synthase1.21.3.10.441
3cs8BRLPeroxisome proliferator-activated receptor gamma/0.441
3ed1GA3Gibberellin receptor GID1/0.441
3jswJARHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.441
3nwq2NCGag-Pol polyprotein3.4.23.160.441
3pqbVGPPutative oxidoreductase/0.441
3ruhNADUDP-N-acetylglucosamine 4-epimerase/0.441
3upf0BUPolyprotein/0.441
3v9v21LPeroxisome proliferator-activated receptor gamma/0.441
4bgePYWEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4c59FEFCyclin-G-associated kinase2.7.11.10.441
4dreNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4dtiNAIEnoyl-[acyl-carrier-protein] reductase [NADH]1.3.1.90.441
4e5kNADPhosphonate dehydrogenase1.20.1.10.441
4h8nNDPNADPH-dependent conjugated polyketone reductase C2/0.441
4ivgANPTNF receptor-associated protein 1/0.441
4mihFADPyranose 2-oxidase1.1.3.100.441
4xey1N1Tyrosine-protein kinase ABL12.7.10.20.441
5c88COAN-alpha-acetyltransferase/0.441
6cp4CAMCamphor 5-monooxygenase1.14.15.10.441
1bdlIM1Gag-Pol polyprotein3.4.23.160.440
1hdgNADGlyceraldehyde-3-phosphate dehydrogenase/0.440
1hzjUD1UDP-glucose 4-epimerase/0.440
1i59ADPChemotaxis protein CheA2.7.13.30.440
1nvsUCMSerine/threonine-protein kinase Chk12.7.11.10.440
1o6kANPRAC-beta serine/threonine-protein kinase2.7.11.10.440
1s60COAAminoglycoside N(6')-acetyltransferase type 1/0.440
1ykdCMPAdenylate cyclase/0.440
1zeoC01Peroxisome proliferator-activated receptor gamma/0.440
2dv3SAHDiphthine synthase/0.440
2ejkSAHDiphthine synthase/0.440
2hr8SAHDiphthine synthase/0.440
2j3kNAPNADPH-dependent oxidoreductase 2-alkenal reductase1.3.1.740.440
2p33J07Mitogen-activated protein kinase 102.7.11.240.440
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.440
2vwz7X6Ephrin type-B receptor 42.7.10.10.440
2wghDTPRibonucleoside-diphosphate reductase large subunit1.17.4.10.440
2wyvNADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
2xvv9DNSerum albumin/0.440
2y3rTRKTamL/0.440
2yhyADPBifunctional UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kinase2.7.1.600.440
2yutNAPPutative short-chain oxidoreductase/0.440
2znq401Peroxisome proliferator-activated receptor delta/0.440
3of4FMNNitroreductase/0.440
3qtwX3ACyclin-dependent kinase 22.7.11.220.440
3tkiS25Serine/threonine-protein kinase Chk12.7.11.10.440
3uqdATPATP-dependent 6-phosphofructokinase isozyme 22.7.1.110.440
3uu114BAnthranilate phosphoribosyltransferase/0.440
3zlx5EZDual specificity mitogen-activated protein kinase kinase 12.7.12.20.440
4at0FADPossible succinate dehydrogenase/0.440
4bieIE6Mitogen-activated protein kinase kinase kinase 52.7.11.250.440
4d0lGSPRas-related protein Rab-11A/0.440
4dptAGSMevalonate diphosphate decarboxylase/0.440
4e1z0MXNon-receptor tyrosine-protein kinase TYK22.7.10.20.440
4is3NAD3alpha-hydroxy bile acid-CoA-ester 3-dehydrogenase 21.17.98.10.440
4jldADPAdenylate kinase/0.440
4m87NADEnoyl-[acyl-carrier-protein] reductase [NADH]/0.440
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.440
4u0mGTPCyclic GMP-AMP synthase/0.440
4udqFAD5-(hydroxymethyl)furfural oxidase/0.440
4xuhSFIPeroxisome proliferator-activated receptor gamma/0.440
4yuqKS1Calmodulin-like domain protein kinase/0.440
5drdATPAurora kinase A2.7.11.10.440
5ijzNAPNADP-specific glutamate dehydrogenase1.4.1.40.440