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sc-PDB

An Annotated Database of Druggable Binding Sites from the Protein DataBank

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Distribution of Binding site similarity measured by Shaper
You can zoom onto the graph by using the mouse to make a selection

Binding Sites are compared using Shaper.
For more information, please see the following publication: Desaphy J. et al. Comparison and Druggability Prediction of protein-Ligand Binding sites from pharmacophore-annotated cavity shapes J. Chem. Inf. Model., 2012, 52(8), pp2287-2299
Binding Sites are considered as similar when the similarity value is greater than 0.44

Reference Protein Data Bank Entry :
PDB IDHETUniprot NameEC Number
1drtPCVClavaminate synthase 11.14.11.21

Complex with similar binding sites

PDB ID HET Uniprot Name EC Number Binding Site
Similarity		 Align
1drtPCVClavaminate synthase 11.14.11.211.000
4oh4ANPProtein BRASSINOSTEROID INSENSITIVE 12.7.10.10.509
2gnhH52cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.496
1nzdUPGDNA beta-glucosyltransferase/0.493
3ibqATPPyridoxal kinase/0.493
4c3f7KWTyrosine-protein kinase Lck2.7.10.20.493
1nzfUPGDNA beta-glucosyltransferase/0.492
2vkvTDCTetracycline repressor protein class D/0.490
2qfxNDPIsocitrate dehydrogenase [NADP], mitochondrial1.1.1.420.489
3h3qH13Collagen type IV alpha-3-binding protein/0.486
2brnDF1Serine/threonine-protein kinase Chk12.7.11.10.485
2vwqNAPGlucose 1-dehydrogenase/0.484
3h3t16HCollagen type IV alpha-3-binding protein/0.484
3junAKDPhenazine biosynthesis protein A/B/0.483
4ft7H3KSerine/threonine-protein kinase Chk12.7.11.10.483
4la1FADThioredoxin glutathione reductase/0.483
2o7oDXTTetracycline repressor protein class D/0.482
2tctCTCTetracycline repressor protein class D/0.482
5ar4SB2Receptor-interacting serine/threonine-protein kinase 22.7.11.10.482
2c1bCQPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.481
3uibSB2Putative mitogen-activated protein kinase/0.481
4z36ON3Lysophosphatidic acid receptor 1/0.480
5fs7FADApoptosis-inducing factor 1, mitochondrial1.1.10.478
2jdsL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
4iazADPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.477
4kprFADThioredoxin reductase 1, cytoplasmic1.8.1.90.477
3hadNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.475
2bi4NADLactaldehyde reductase1.1.1.770.474
2xrlDXTTetracycline repressor protein class D/0.474
4b3aTACTetracycline repressor protein class D/0.474
1msmJE2Gag-Pol polyprotein3.4.23.160.473
1orkATCTetracycline repressor protein class D/0.473
2f7x4EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.473
2wxvWXVCyclin-dependent kinase 22.7.11.220.473
2y6o1N1Ephrin type-A receptor 42.7.10.10.473
3u9eCOALmo1369 protein/0.473
1ovmTPPIndole-3-pyruvate decarboxylase4.1.1.740.472
2vesGVRUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.472
4dptAGSMevalonate diphosphate decarboxylase/0.472
4fv3EK6Mitogen-activated protein kinase 12.7.11.240.472
4pd6URINucleoside permease/0.472
2rqfJH3Hemolymph juvenile hormone binding protein/0.471
2vu3LZECyclin-dependent kinase 22.7.11.220.471
2wihP48Cyclin-dependent kinase 22.7.11.220.471
3qfbFADThioredoxin reductase 1, cytoplasmic1.8.1.90.471
3r6sCMPCRP-like cAMP-activated global transcriptional regulator/0.471
4xczFONQdtf/0.471
4y9qC2EUncharacterized protein/0.471
1jdvADNPurine nucleoside phosphorylase/0.470
3oogYTPcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.470
4fgcPQ0NADPH-dependent 7-cyano-7-deazaguanine reductase1.7.1.130.470
1e5qNDPSaccharopine dehydrogenase [NADP(+), L-glutamate-forming]1.5.1.100.469
2iiqC5PAlpha-2,3/2,6-sialyltransferase/sialidase/0.469
2z1mNDPGDP-mannose 4,6-dehydratase/0.469
3flyFLYMitogen-activated protein kinase 14/0.469
3mvjXFEcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.469
1y2k7DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.468
2ghlLIBMitogen-activated protein kinase 14/0.468
2zjwREFCasein kinase II subunit alpha2.7.11.10.468
3apfBMWPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.468
3iaaTYDCalG2/0.468
3fwjCAMCamphor 5-monooxygenase1.14.15.10.467
5f8eSAHPossible transcriptional regulatory protein/0.467
1fm4DXCMajor pollen allergen Bet v 1-L/0.466
1zp9ATPRIO-type serine/threonine-protein kinase Rio12.7.11.10.466
2c29NAPDihydroflavonol 4-reductase/0.466
2xdoFADTetX family tetracycline inactivation enzyme/0.466
3h3cP1EProtein-tyrosine kinase 2-beta2.7.10.20.466
3hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.466
4bkz1WSMaternal embryonic leucine zipper kinase2.7.11.10.466
1c70L75Protease/0.465
1xddAAYIntegrin alpha-L/0.465
4h1e10JBeta-secretase 13.4.23.460.465
1mrwK57Gag-Pol polyprotein3.4.23.160.464
1v59FADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.464
2j9gANPBiotin carboxylase6.3.4.140.464
2vttLZDCyclin-dependent kinase 22.7.11.220.464
2xyuQ9GEphrin type-A receptor 42.7.10.10.464
3fr5I4AFatty acid-binding protein, adipocyte/0.464
3h3sH15Collagen type IV alpha-3-binding protein/0.464
4aa4QC0Mitogen-activated protein kinase 14/0.464
5fkoTDCTetracycline repressor protein class D/0.464
2ab8MTPAdenosine kinase2.7.1.200.463
2zjmF1MBeta-secretase 13.4.23.460.463
3clrFADElectron transfer flavoprotein subunit alpha/0.463
3r9nZ68Cyclin-dependent kinase 22.7.11.220.463
4gk3L87Ephrin type-A receptor 32.7.10.10.463
4ifcADPSerine/threonine-protein kinase PRP4 homolog2.7.11.10.463
4z0g5GPInosine-5'-monophosphate dehydrogenase/0.463
1xe55FEPlasmepsin-23.4.23.390.462
3hllI45Mitogen-activated protein kinase 14/0.462
4d7mTDCTetracycline repressor protein class D/0.462
4dpy2P0Mevalonate diphosphate decarboxylase/0.462
4hnc0UTMandelate racemase/0.462
4qmySTUSerine/threonine-protein kinase 242.7.11.10.462
1bwsNDPGDP-L-fucose synthase/0.461
1sguMK1Gag-Pol polyprotein3.4.23.160.461
1tj0FADBifunctional protein PutA1.5.5.20.461
1y2e5DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.461
3fln3FNMitogen-activated protein kinase 14/0.461
3lqfNADGalactitol dehydrogenase/0.461
4ftkH9KSerine/threonine-protein kinase Chk12.7.11.10.461
4gd40WSLysine-specific demethylase 4A1.14.110.461
1f17NAIHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.460
1qpjSTUTyrosine-protein kinase Lck2.7.10.20.460
2ea4F79Methionine aminopeptidase 2/0.460
2qc8ADPGlutamine synthetase6.3.1.20.460
2vn9GVDCalcium/calmodulin-dependent protein kinase type II subunit delta2.7.11.170.460
2xpvMIYTetracycline repressor protein class D/0.460
3mpt1GKMitogen-activated protein kinase 14/0.460
4j57FADThioredoxin reductase 21.8.1.90.460
4uwmFMN3,6-diketocamphane 1,6 monooxygenase1.14.130.460
1ykdCMPAdenylate cyclase/0.459
1zrqFAD5,10-methylenetetrahydrofolate reductase1.5.1.200.459
2b53D23Cyclin-dependent kinase 22.7.11.220.459
2c3kABOSerine/threonine-protein kinase Chk12.7.11.10.459
2fvdLIACyclin-dependent kinase 22.7.11.220.459
2hdhNADHydroxyacyl-coenzyme A dehydrogenase, mitochondrial1.1.1.350.459
3bk2U5PRibonuclease J/0.459
3u9n09HSerine/threonine-protein kinase Chk12.7.11.10.459
3wycNAPMeso-diaminopimelate D-dehydrogenase1.4.1.160.459
4a81DXCMajor pollen allergen Bet v 1-A/0.459
4e5j581Polymerase acidic protein/0.459
4h4zFADBiphenyl dioxygenase ferredoxin reductase subunit/0.459
4kkyCAMCamphor 5-monooxygenase1.14.15.10.459
4mxxDB8Proto-oncogene tyrosine-protein kinase Src2.7.10.20.459
5fkmTDCTetracycline repressor protein class D/0.459
4z35ON9Lysophosphatidic acid receptor 1/0.459
1f28UMPThymidylate synthase2.1.1.450.458
1sd2MTHS-methyl-5'-thioadenosine phosphorylase/0.458
2c68CT6Cyclin-dependent kinase 22.7.11.220.458
2e9uA25Serine/threonine-protein kinase Chk12.7.11.10.458
3etdNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.458
3w0nANPHygromycin-B 4-O-kinase2.7.1.1630.458
4a6bQG8Gag-Pol polyprotein3.4.23.160.458
4du82P0Mevalonate diphosphate decarboxylase/0.458
4h4uFADBiphenyl dioxygenase ferredoxin reductase subunit/0.458
4o4fATPKinase/0.458
1esqTZPHydroxyethylthiazole kinase/0.457
1k6pXN3Gag-Pol polyprotein3.4.23.160.457
1rejB1LcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.457
2a7r5GPGMP reductase 2/0.457
2brbPFQSerine/threonine-protein kinase Chk12.7.11.10.457
2brmDFZSerine/threonine-protein kinase Chk12.7.11.10.457
2ooyATP5'-AMP-activated protein kinase subunit gamma/0.457
2pwcG3GGag-Pol polyprotein3.4.23.160.457
3dogNNNCyclin-dependent kinase 22.7.11.220.457
3i7eDJRGag-Pol polyprotein/0.457
3o0o5ADVitamin B12-dependent ribonucleotide reductase/0.457
3rvhHQ2Lysine-specific demethylase 4A1.14.110.457
3sj7NDP3-oxoacyl-(Acyl-carrier-protein) reductase, putative/0.457
4anwO92Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.457
4zp1TPPPyruvate decarboxylase4.1.1.10.457
1lf2R37Plasmepsin-23.4.23.390.456
1tytFADTrypanothione reductase1.8.1.120.456
2a58RBF6,7-dimethyl-8-ribityllumazine synthase2.5.1.780.456
2p33J07Mitogen-activated protein kinase 102.7.11.240.456
2pmnK51Protein kinase 7/0.456
2xpwOTCTetracycline repressor protein class D/0.456
3d2pCOAAmino-acid acetyltransferase/0.456
3ddw055Glycogen phosphorylase, liver form2.4.1.10.456
3fhxPLPPyridoxal kinase2.7.1.350.456
3flzFLZMitogen-activated protein kinase 14/0.456
4anx534Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.456
4auxXTCTetracycline repressor protein class D/0.456
4i231C9Epidermal growth factor receptor2.7.10.10.456
1hb1OCVIsopenicillin N synthase1.21.3.10.455
1n77ATPGlutamate--tRNA ligase6.1.1.170.455
1qlhNADAlcohol dehydrogenase E chain1.1.1.10.455
2pxaSAHGenome polyprotein2.7.7.480.455
2qtgMTH5'-methylthioadenosine/S-adenosylhomocysteine nucleosidase 13.2.2.90.455
2zbaZBATrichothecene 3-O-acetyltransferase/0.455
4dc0NDPPutative ketoacyl reductase1.3.10.455
4ewn0VRImidazole glycerol phosphate synthase subunit HisF4.1.30.455
4zj8SUVOrexin receptor type 1/0.455
1rx1NAPDihydrofolate reductase1.5.1.30.454
2ddoATPPyridoxine/pyridoxal/pyridoxamine kinase/0.454
2ivpATPtRNA N6-adenosine threonylcarbamoyltransferase/0.454
2nnqT4BFatty acid-binding protein, adipocyte/0.454
2qo9ANPEphrin type-A receptor 32.7.10.10.454
2trtTACTetracycline repressor protein class D/0.454
2v4lABJPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.454
3t6iNC8Endothiapepsin3.4.23.220.454
4kzoNAPIsocitrate dehydrogenase [NADP] cytoplasmic1.1.1.420.454
5d3fFSC14-3-3 protein zeta/delta/0.454
1ezvUQ6Cytochrome b/0.453
1g1aNADdTDP-glucose 4,6-dehydratase/0.453
1u59STUTyrosine-protein kinase ZAP-702.7.10.20.453
2fj1CTCTetracycline repressor protein class D/0.453
3fp0FP015-O-acetyltransferase/0.453
3hyoADPPyridoxal kinase/0.453
4ft5H2KSerine/threonine-protein kinase Chk12.7.11.10.453
4gavFADRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.453
4gyzD5MTyrosyl-DNA phosphodiesterase 23.1.40.453
4uirFADOleate hydratase4.2.1.530.453
4z61ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.453
4z64ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.453
1dliUDXUDP-glucose 6-dehydrogenase/0.452
1febFADTrypanothione reductase1.8.1.120.452
1j39UPGDNA beta-glucosyltransferase/0.452
1kzkJE2Gag-Pol polyprotein3.4.23.160.452
1q8wM77cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.452
1wvySTUDeath-associated protein kinase 12.7.11.10.452
1x14NADNAD(P) transhydrogenase subunit alpha1.6.1.20.452
1y2c3DEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.452
1y9dTPPPyruvate oxidase1.2.3.30.452
2a0yDIHPurine nucleoside phosphorylase2.4.2.10.452
2iviACWIsopenicillin N synthase1.21.3.10.452
2r0uM54Serine/threonine-protein kinase Chk12.7.11.10.452
2y3sTIRTamL/0.452
2y60M8FIsopenicillin N synthase1.21.3.10.452
3dj4UD1Bifunctional protein GlmU/0.452
3fr8NDPKetol-acid reductoisomerase, chloroplastic1.1.1.860.452
3l7dDK5Glycogen phosphorylase, muscle form2.4.1.10.452
3lxiCAMCytochrome P450/0.452
3ox4NADAlcohol dehydrogenase 21.1.1.10.452
3sqxANPATP-dependent RNA helicase MSS116, mitochondrial3.6.4.130.452
4g3sUD1Bifunctional protein GlmU/0.452
4hvb19PPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.452
4s26SAHPhosphomethylpyrimidine synthase, chloroplastic4.1.99.170.452
5fm7ADPRuvB-like helicase/0.452
1g41ADPATP-dependent protease ATPase subunit HslU/0.451
1hbvGANGag-Pol polyprotein/0.451
1ywnLIFVascular endothelial growth factor receptor 22.7.10.10.451
1zthADPRIO-type serine/threonine-protein kinase Rio12.7.11.10.451
2aznNAP2,5-diamino-6-ribosylamino-4(3H)-pyrimidinone 5'-phosphate reductase/0.451
2bl4NADLactaldehyde reductase1.1.1.770.451
2fhjH4ZFormylmethanofuran--tetrahydromethanopterin formyltransferase2.3.1.1010.451
2g5cNADPrephenate dehydrogenase/0.451
2q7vFADThioredoxin reductase/0.451
2qaeFADDihydrolipoyl dehydrogenase1.8.1.40.451
2vkeTACTetracycline repressor protein class D/0.451
2xrwANPMitogen-activated protein kinase 82.7.11.240.451
3akm11DFatty acid-binding protein, intestinal/0.451
3bhtMFRCyclin-dependent kinase 22.7.11.220.451
3cvuFADRE11660p/0.451
3i81EBIInsulin-like growth factor 1 receptor2.7.10.10.451
3kjsNAPBifunctional dihydrofolate reductase-thymidylate synthase/0.451
3o56ZG1cAMP-specific 3',5'-cyclic phosphodiesterase 4B3.1.4.530.451
3raiX85Cyclin-dependent kinase 22.7.11.220.451
3sdi3SDProteasome subunit beta type-53.4.25.10.451
3sdi3SDProteasome subunit beta type-63.4.25.10.451
4a99FADTetX family tetracycline inactivation enzyme/0.451
4f6w0SSCyclin-dependent kinase 82.7.11.220.451
4g3pUD1Bifunctional protein GlmU/0.451
5cwa0GAAnthranilate synthase component 14.1.3.270.451
5e8ySTUTGF-beta receptor type-22.7.11.300.451
1kp2ATPArgininosuccinate synthase6.3.4.50.450
2a9y26AAdenosine kinase2.7.1.200.450
2cv2GSUGlutamate--tRNA ligase6.1.1.170.450
2f7e2EAcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.450
2jb4A14Isopenicillin N synthase1.21.3.10.450
2pwrG4GGag-Pol polyprotein3.4.23.160.450
2qnqQN3Gag-Pol polyprotein3.4.23.160.450
2wghDTPRibonucleoside-diphosphate reductase large subunit1.17.4.10.450
3cy2MB9Serine/threonine-protein kinase pim-12.7.11.10.450
3eldSFGMethyltransferase/0.450
3iphG11Mitogen-activated protein kinase 14/0.450
3r8zZ63Cyclin-dependent kinase 22.7.11.220.450
3tvuB37Acetyl-CoA carboxylase/0.450
3vmmP0DAlanine--anticapsin ligase/0.450
4dbzNDPPutative ketoacyl reductase1.3.10.450
4dnaFADProbable glutathione reductase/0.450
4dxd9PCCell division protein FtsZ/0.450
4fhk0U0Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.450
4prvADPDNA gyrase subunit B/0.450
4qmwKS1Serine/threonine-protein kinase 242.7.11.10.450
5a88ADPRiboflavin biosynthesis protein RibF2.7.1.260.450
5c1mCLRMu-type opioid receptor/0.450
5c8yACPTubulin tyrosine ligase/0.450
1k27MTMS-methyl-5'-thioadenosine phosphorylase/0.449
1np7FADCryptochrome DASH/0.449
1qbgFADNAD(P)H dehydrogenase [quinone] 11.6.5.20.449
1qo8FADFumarate reductase flavoprotein subunit/0.449
1rc1KT3Trifunctional purine biosynthetic protein adenosine-32.1.2.20.449
1t87CAMCamphor 5-monooxygenase1.14.15.10.449
1vyw292Cyclin-dependent kinase 22.7.11.220.449
1y5rC0RCorticosteroid 11-beta-dehydrogenase isozyme 11.1.1.1460.449
2b4qNAPRhamnolipids biosynthesis 3-oxoacyl-[acyl-carrier-protein] reductase1.1.1.1000.449
2chz093Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.449
2ea2F77Methionine aminopeptidase 2/0.449
2ituITQEpidermal growth factor receptor2.7.10.10.449
2oapANPType II secretion system protein (GspE-2)/0.449
2uztSS3cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
2vwhNAPGlucose 1-dehydrogenase/0.449
3ae4FADSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial/0.449
3au8NDP1-deoxy-D-xylulose 5-phosphate reductoisomerase, apicoplastic1.1.1.2670.449
3e8nVRADual specificity mitogen-activated protein kinase kinase 12.7.12.20.449
3fwyADPLight-independent protochlorophyllide reductase iron-sulfur ATP-binding protein/0.449
3kkvB99cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.449
3oev3OEProteasome subunit beta type-53.4.25.10.449
3oev3OEProteasome subunit beta type-63.4.25.10.449
3rdqDTBStreptavidin/0.449
4a6nFADTetX family tetracycline inactivation enzyme/0.449
4b99R4LMitogen-activated protein kinase 72.7.11.240.449
4c9pCAMCytochrome P450/0.449
4dan2FAPurine nucleoside phosphorylase DeoD-type2.4.2.10.449
4g090VDHistidinol dehydrogenase/0.449
4hge15VTyrosine-protein kinase JAK2/0.449
4ho5DAUGlucose-1-phosphate thymidylyltransferase/0.449
4p9dTMPDeoxycytidylate deaminase/0.449
4u7wNDPMxaA/0.449
4z63ILE_THR_GLN_TYS_TYSPhytosulfokine receptor 12.7.11.10.449
5cb4ACPTubulin tyrosine ligase/0.449
1e8wQUEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
1hb3SCVIsopenicillin N synthase1.21.3.10.448
1sxjAGSReplication factor C subunit 1/0.448
1zmcFADDihydrolipoyl dehydrogenase, mitochondrial1.8.1.40.448
2bu2ATP[Pyruvate dehydrogenase (acetyl-transferring)] kinase isozyme 2, mitochondrial2.7.11.20.448
2cy0NAPShikimate dehydrogenase (NADP(+))/0.448
2eq8FADDihydrolipoyl dehydrogenase/0.448
2i40BLZCyclin-dependent kinase 22.7.11.220.448
2rlcCHDCholoylglycine hydrolase3.5.1.240.448
2vprTDCTetracycline repressor protein class H/0.448
2xf3J01Uncharacterized protein/0.448
3dylIBMHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3fwiCAMCamphor 5-monooxygenase1.14.15.10.448
3h3r14HCollagen type IV alpha-3-binding protein/0.448
3jsiWTCHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.448
3lm9ADPPutative fructokinase2.7.1.40.448
3td7FADProbable FAD-linked sulfhydryl oxidase R5961.8.3.20.448
4bbxLKFcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.448
4ezk0SDPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.448
4ft0HK9Serine/threonine-protein kinase Chk12.7.11.10.448
4m52FADDihydrolipoyl dehydrogenase1.8.1.40.448
1l3iSAHProbable cobalt-precorrin-6B C(15)-methyltransferase (decarboxylating)/0.447
1sxjADPReplication factor C subunit 5/0.447
2balPQAMitogen-activated protein kinase 14/0.447
2brgDFYSerine/threonine-protein kinase Chk12.7.11.10.447
2chx090Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
2e20B4PPropionate kinase/0.447
2emuSAHDiphthine synthase/0.447
2npxFADNADH peroxidase1.11.1.10.447
2rg5279Mitogen-activated protein kinase 14/0.447
2uzuL20cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.447
2xgoZKDUncharacterized protein/0.447
3dynPCGHigh affinity cGMP-specific 3',5'-cyclic phosphodiesterase 9A/0.447
3fowIMHPurine nucleoside phosphorylase/0.447
3isjA8DPantothenate synthetase6.3.2.10.447
3p5pA3CTaxadiene synthase4.2.3.170.447
3q5dGDPAtlastin-13.6.50.447
3r1rATPRibonucleoside-diphosphate reductase 1 subunit alpha1.17.4.10.447
3r9iADPSeptum site-determining protein MinD/0.447
3sdkP3NProteasome subunit beta type-53.4.25.10.447
3sdkP3NProteasome subunit beta type-63.4.25.10.447
3sls77DDual specificity mitogen-activated protein kinase kinase 12.7.12.20.447
3sni546cAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.447
3uk6ADPRuvB-like 23.6.4.120.447
3zh8C58Protein kinase C iota type2.7.11.130.447
3zm5IGMUDP-N-acetylmuramoyl-tripeptide--D-alanyl-D-alanine ligase/0.447
4aqc88ATyrosine-protein kinase JAK2/0.447
4hle17VPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.447
4jdrFADDihydrolipoyl dehydrogenase1.8.1.40.447
4nm9FADBifunctional protein PutA/0.447
5b1yNDP3-oxoacyl-[acyl-carrier-protein] reductase/0.447
1bcpATPPertussis toxin subunit 4/0.446
1bcpATPPertussis toxin subunit 5/0.446
1bk0ACVIsopenicillin N synthase1.21.3.10.446
1e8xATPPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
1fxsNAPGDP-L-fucose synthase/0.446
1me7RVPInosine-5'-monophosphate dehydrogenase/0.446
1rfvADPPyridoxal kinase2.7.1.350.446
2e9v85ASerine/threonine-protein kinase Chk12.7.11.10.446
2hmaSAMtRNA-specific 2-thiouridylase MnmA/0.446
2v13C40Renin3.4.23.150.446
2vx07X7Ephrin type-B receptor 42.7.10.10.446
2x0rNADMalate dehydrogenase/0.446
3a99ANPSerine/threonine-protein kinase pim-12.7.11.10.446
3dgaNDPBifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.446
3ed1GA3Gibberellin receptor GID1/0.446
3hazFADBifunctional protein PutA/0.446
3hv71AUMitogen-activated protein kinase 14/0.446
3ivgFG5Pantothenate synthetase6.3.2.10.446
3lj3WYEPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.446
3nefPYVAbscisic acid receptor PYL1/0.446
3ozd4CTS-methyl-5'-thioadenosine phosphorylase/0.446
3pb3SAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.446
3qt62P0Mevalonate diphosphate decarboxylase/0.446
3sptUD1Bifunctional protein GlmU/0.446
4baqM4ZProthrombin3.4.21.50.446
4dt9GMPAPH(2'')-Id/0.446
4e5yNDPGDP-L-fucose synthase1.1.1.2710.446
4jvf17XRetinal rod rhodopsin-sensitive cGMP 3',5'-cyclic phosphodiesterase subunit delta/0.446
4looSB4Mitogen-activated protein kinase 14/0.446
4nl4ADPPrimosomal protein N'/0.446
4wpuGDPPhosphoenolpyruvate carboxykinase [GTP]/0.446
4xj43ATCyclic GMP-AMP synthase/0.446
4zolACPTubulin tyrosine ligase/0.446
1esvLARActin, alpha skeletal muscle/0.445
1fwkADPHomoserine kinase2.7.1.390.445
1h65GDPTranslocase of chloroplast 343.6.50.445
1jtvTESEstradiol 17-beta-dehydrogenase 11.1.1.620.445
1mkdZARcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1nvqUCNSerine/threonine-protein kinase Chk12.7.11.10.445
1p84UQ6Cytochrome b/0.445
1q4l679Glycogen synthase kinase-3 beta2.7.11.260.445
1u3cFADCryptochrome-1/0.445
1xonPILcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1y2bDEEcAMP-specific 3',5'-cyclic phosphodiesterase 4D3.1.4.530.445
1yc443PHeat shock protein HSP 90-alpha/0.445
2feuCAMCamphor 5-monooxygenase1.14.15.10.445
2gv8NDPThiol-specific monooxygenase1.14.130.445
2qbuSAHPrecorrin-2 methyltransferase/0.445
2qhm7CSSerine/threonine-protein kinase Chk12.7.11.10.445
2r9zFADGlutathione amide reductase/0.445
2wnsOMPUridine 5'-monophosphate synthase2.4.2.100.445
3fwfCAMCamphor 5-monooxygenase1.14.15.10.445
3h4vNAPPteridine reductase 11.5.1.330.445
3hx4ANPCalmodulin-domain protein kinase 1/0.445
3mvqNDPGlutamate dehydrogenase 1, mitochondrial1.4.1.30.445
3ov4EQUSteroid Delta-isomerase5.3.3.10.445
3v94WYQPhosphodiesterase/0.445
3vjoANPEpidermal growth factor receptor2.7.10.10.445
3x2eNAIAdenosylhomocysteinase/0.445
4gk4L90Ephrin type-A receptor 32.7.10.10.445
4ho8UPGGlucose-1-phosphate thymidylyltransferase/0.445
4ho9GDUGlucose-1-phosphate thymidylyltransferase/0.445
4ihl1F514-3-3 protein zeta/delta/0.445
4l3l5FIRibosomal protein S6 kinase beta-12.7.11.10.445
4rrvATP3-phosphoinositide-dependent protein kinase 12.7.11.10.445
1c2tNHSPhosphoribosylglycinamide formyltransferase/0.444
1dz8CAMCamphor 5-monooxygenase1.14.15.10.444
1e8zSTUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
1j49NADD-lactate dehydrogenase1.1.1.280.444
2henADPEphrin type-B receptor 22.7.10.10.444
2ijgFADCryptochrome DASH, chloroplastic/mitochondrial/0.444
2ou5FMNPyridoxamine 5'-phosphate oxidase-related FMN-binding protein/0.444
2ourCMPcAMP and cAMP-inhibited cGMP 3',5'-cyclic phosphodiesterase 10A3.1.4.170.444
2r0cFADPutative FAD-monooxygenase/0.444
3c3eFO12-phospho-L-lactate transferase/0.444
3d84NDPDihydrofolate reductase1.5.1.30.444
3ekuATPActin-5C/0.444
3g5sFADMethylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO/0.444
3l5dBDVBeta-secretase 13.4.23.460.444
3oibFDAPutative acyl-CoA dehydrogenase/0.444
3p2eSAH16S rRNA (adenine(1408)-N(1))-methyltransferase2.1.1.1800.444
4a84DXCMajor pollen allergen Bet v 1-A/0.444
4dtaADNAPH(2'')-Id/0.444
4eagATP5'-AMP-activated protein kinase subunit gamma-1/0.444
4fk1FADPutative thioredoxin reductase/0.444
4ftq4HKSerine/threonine-protein kinase Chk12.7.11.10.444
4ful0VUPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4g3qUD1Bifunctional protein GlmU/0.444
4gb90WRPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.444
4hyvPEPPyruvate kinase 12.7.1.400.444
4iv6FDAIsovaleryl-CoA dehydrogenase/0.444
4kfbT27Gag-Pol polyprotein2.7.7.490.444
4lcg1WMUDP-3-O-acyl-N-acetylglucosamine deacetylase/0.444
4ldkFADFAD-linked sulfhydryl oxidase ALR1.8.3.20.444
4m6jNDPDihydrofolate reductase1.5.1.30.444
4otwDB8Receptor tyrosine-protein kinase erbB-32.7.10.10.444
4xz3COAAcyl-CoA synthetase (NDP forming)/0.444
5fdg0N8Polymerase acidic protein/0.444
1d7aAIRN5-carboxyaminoimidazole ribonucleotide mutase/0.443
1gjvAGS[3-methyl-2-oxobutanoate dehydrogenase [lipoamide]] kinase, mitochondrial2.7.11.40.443
1k6tXN1Gag-Pol polyprotein3.4.23.160.443
1t7i017Gag-Pol polyprotein3.4.23.160.443
1thyUMPThymidylate synthase/0.443
1w2xRCPAcetyl-CoA carboxylase/0.443
2d8aNADL-threonine 3-dehydrogenase/0.443
2fxv5GPXanthine phosphoribosyltransferase2.4.2.220.443
2q9fC3SCholesterol 24-hydroxylase/0.443
2r3p3SCCyclin-dependent kinase 22.7.11.220.443
2rioADPSerine/threonine-protein kinase/endoribonuclease IRE12.7.11.10.443
2xa4AZ5Tyrosine-protein kinase JAK2/0.443
3e8xNAPBH1520 protein/0.443
3krwBA1Beta-adrenergic receptor kinase 12.7.11.150.443
3lfsA07Cyclin-dependent kinase 22.7.11.220.443
3nc9TR3Ketohexokinase/0.443
3nj0PYVAbscisic acid receptor PYL2/0.443
3wrjCAMCamphor 5-monooxygenase1.14.15.10.443
4dx7DM2Multidrug efflux pump subunit AcrB/0.443
4f4dCHDFerrochelatase, mitochondrial4.99.1.10.443
4ho2THMGlucose-1-phosphate thymidylyltransferase/0.443
4jq7KJQEpidermal growth factor receptor2.7.10.10.443
4l7f1V5Mitogen-activated protein kinase 82.7.11.240.443
4nbtNAD3-oxoacyl-[acyl-carrier-protein] reductase/0.443
4nmbFADBifunctional protein PutA/0.443
4opgFDAConserved Archaeal protein/0.443
4tm0FADKtzI/0.443
4u97STUInterleukin-1 receptor-associated kinase 42.7.11.10.443
1bwlFMNNADPH dehydrogenase 11.6.99.10.442
1dssNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1f8fNADBenzyl alcohol dehydrogenase/0.442
1gpuTHDTransketolase 12.2.1.10.442
1ia3TQ5Dihydrofolate reductase1.5.1.30.442
1ia4TQ6Dihydrofolate reductase1.5.1.30.442
1j0xNADGlyceraldehyde-3-phosphate dehydrogenase1.2.1.120.442
1pjkANPCasein kinase II subunit alpha2.7.11.10.442
1sd1FMCS-methyl-5'-thioadenosine phosphorylase/0.442
1wbk568Pol protein/0.442
1zk7FADMercuric reductase1.16.1.10.442
2ag0TPPBenzaldehyde lyase/0.442
2oh02PYcAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.442
2oo5TXDNAD(P) transhydrogenase subunit alpha part 11.6.1.20.442
2q5oPPYIndole-3-pyruvate decarboxylase4.1.1.740.442
2wwjY28Lysine-specific demethylase 4A/0.442
2xszATPRuvB-like 23.6.4.120.442
3f47I2C5,10-methenyltetrahydromethanopterin hydrogenase1.12.98.20.442
3fskRO6Mitogen-activated protein kinase 14/0.442
3fwgCAMCamphor 5-monooxygenase1.14.15.10.442
3gjwGJWPoly [ADP-ribose] polymerase 12.4.2.300.442
3ieuGDPGTPase Era/0.442
3k2xI5A2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.442
3qfxCP6Bifunctional dihydrofolate reductase-thymidylate synthase1.5.1.30.442
4a83DXCMajor pollen allergen Bet v 1-A/0.442
4btjATPTau-tubulin kinase 12.7.11.10.442
4ck2NVUIntegrase/0.442
4cukNAID-lactate dehydrogenase/0.442
4g73NAIRotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial1.6.5.90.442
4gk2L66Ephrin type-A receptor 32.7.10.10.442
4mv3ACPBiotin carboxylase6.3.4.140.442
4o1pANPRibonuclease L/0.442
4riyADPEpidermal growth factor receptor2.7.10.10.442
4u0mATPCyclic GMP-AMP synthase/0.442
6cp4CAMCamphor 5-monooxygenase1.14.15.10.442
1bl6SB6Mitogen-activated protein kinase 14/0.441
1bozPRDDihydrofolate reductase1.5.1.30.441
1bxoPP7Penicillopepsin-13.4.23.200.441
1hdcCBO3-alpha-(or 20-beta)-hydroxysteroid dehydrogenase1.1.1.530.441
1ykr628Cyclin-dependent kinase 22.7.11.220.441
2bdf24AProto-oncogene tyrosine-protein kinase Src2.7.10.20.441
2e9n76ASerine/threonine-protein kinase Chk12.7.11.10.441
2f3rG5PGuanylate kinase2.7.4.80.441
2hckQUETyrosine-protein kinase HCK2.7.10.20.441
2jk6FADTrypanothione reductase/0.441
2nv4SAMS-adenosyl-L-methionine-binding protein AF_0241/0.441
2oj9BMIInsulin-like growth factor 1 receptor2.7.10.10.441
2vo7M05cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.441
2x8iX8ISerine/threonine-protein kinase Chk12.7.11.10.441
2xchCKG3-phosphoinositide-dependent protein kinase 12.7.11.10.441
3aidARQGag-Pol polyprotein3.4.23.160.441
3bv2P38Mitogen-activated protein kinase 14/0.441
3d8vUD1Bifunctional protein GlmU/0.441
3h86AP5Adenylate kinase/0.441
3jvhHHV2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase/0.441
3m0wP77Protein S100-A4/0.441
3mpiFADGlutaryl-CoA dehydrogenase1.3.99.320.441
3mxdK53Gag-Pol polyprotein3.4.23.160.441
3pe2E1BCasein kinase II subunit alpha2.7.11.10.441
3pj8404Cyclin-dependent kinase 22.7.11.220.441
4fsqHK3Serine/threonine-protein kinase Chk12.7.11.10.441
4imoPWZProstaglandin-H2 D-isomerase5.3.99.20.441
5cuqNSCGenome polyprotein/0.441
5dn1AMZPhosphoribosyl isomerase A5.3.1.160.441
5e8wSTUTGF-beta receptor type-12.7.11.300.441
1bdbNADCis-2,3-dihydrobiphenyl-2,3-diol dehydrogenase/0.440
1cg6MTAS-methyl-5'-thioadenosine phosphorylase/0.440
1k6cMK1Gag-Pol polyprotein3.4.23.160.440
1meiXMPInosine-5'-monophosphate dehydrogenase/0.440
1nhhANPDNA mismatch repair protein MutL/0.440
1qf5RPLAdenylosuccinate synthetase/0.440
1xkvATPPhosphoenolpyruvate carboxykinase (ATP)/0.440
2a5uQYTPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit gamma isoform2.7.1.1530.440
2cduFADNADH oxidase/0.440
2ft9CHDFatty acid-binding protein 2, liver/0.440
2ga2A19Methionine aminopeptidase 2/0.440
2ijmADPFocal adhesion kinase 12.7.10.20.440
2j3nFADThioredoxin reductase 1, cytoplasmic1.8.1.90.440
2j4dFADCryptochrome DASH, chloroplastic/mitochondrial/0.440
2pym1UNGag-Pol polyprotein3.4.23.160.440
2q46NAPUncharacterized protein At5g02240/0.440
2q5oTPWIndole-3-pyruvate decarboxylase4.1.1.740.440
2qocANPEphrin type-A receptor 32.7.10.10.440
2uzwSS4cAMP-dependent protein kinase catalytic subunit alpha2.7.11.110.440
2ww4ADP4-diphosphocytidyl-2-C-methyl-D-erythritol kinase2.7.1.1480.440
2yj5ATPCopper-transporting ATPase/0.440
3dt1P40Mitogen-activated protein kinase 14/0.440
3enkUPGUDP-glucose 4-epimerase/0.440
3fr28CAFatty acid-binding protein, adipocyte/0.440
3fr4F8AFatty acid-binding protein, adipocyte/0.440
3gbuATPUncharacterized sugar kinase PH14592.7.10.440
3mwuBK3Calmodulin-domain protein kinase 1, putative/0.440
3mx2TTPNucleoprotein/0.440
3q1fYPPBeta-lactamase/0.440
3r04UNQSerine/threonine-protein kinase pim-12.7.11.10.440
3rahO1ZCyclin-dependent kinase 22.7.11.220.440
3tnlNADShikimate dehydrogenase (NADP(+))/0.440
3vi2HMZOrotidine 5'-monophosphate decarboxylase/0.440
3zoiM2WIsopenicillin N synthase1.21.3.10.440
3zxsFADDeoxyribodipyrimidine photolyase-related protein/0.440
4a0rDTBBifunctional dethiobiotin synthetase/7,8-diamino-pelargonic acid aminotransferase, mitochondrial6.3.3.30.440
4a87NARMajor pollen allergen Bet v 1-A/0.440
4aicNDP1-deoxy-D-xylulose 5-phosphate reductoisomerase/0.440
4ctjSAMGenome polyprotein/0.440
4dpuAGSMevalonate diphosphate decarboxylase/0.440
4fsmHK1Serine/threonine-protein kinase Chk12.7.11.10.440
4fsrHKCSerine/threonine-protein kinase Chk12.7.11.10.440
4fxy0W2Neurolysin, mitochondrial3.4.24.160.440
4g2fC07Ephrin type-A receptor 32.7.10.10.440
4gh2HK0Serine/threonine-protein kinase Chk12.7.11.10.440
4gmy0X5Tyrosine-protein kinase JAK2/0.440
4iwo1H4Serine/threonine-protein kinase TBK12.7.11.10.440
4kxn6K62'-deoxynucleoside 5'-phosphate N-hydrolase 1/0.440
4l4xNDPAmphI/0.440
4oztP1AEcdysone receptor, putative/0.440
4qgiROCGag-Pol polyprotein3.4.23.160.440