sc-PDB
An Annotated Database of Druggable Binding Sites from the Protein DataBank
An Annotated Database of Druggable Binding Sites from the Protein DataBank
Binding Modes are compared using Grim.
For more information, please see the following publication:
Desaphy J. et al. Encoding Protein-Ligand Interaction Patterns in Fingerprints and Graphs J. Chem. Inf. Model., 2013, 53 (3), pp 623-637
Binding modes are considered as similar when the similarity value is greater than 0.65
| PDB ID | HET | Uniprot Name | EC Number |
|---|---|---|---|
| 3cge | FAD | Coenzyme A disulfide reductase |
| PDB ID | HET | Uniprot Name | EC Number | Binding Mode Similarity |
Align |
|---|---|---|---|---|---|
| 3cge | FAD | Coenzyme A disulfide reductase | / | 1.395 | |
| 3cgd | FAD | Coenzyme A disulfide reductase | / | 1.369 | |
| 3cgb | FAD | Coenzyme A disulfide reductase | / | 1.272 | |
| 3cgc | FAD | Coenzyme A disulfide reductase | / | 1.247 | |
| 2eq6 | FAD | Dihydrolipoyl dehydrogenase | / | 0.904 | |
| 3nt6 | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.895 | |
| 3nta | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.892 | |
| 3ict | FAD | Coenzyme A disulfide reductase | / | 0.890 | |
| 4ocg | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.887 | |
| 5fs9 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.886 | |
| 2q7v | FAD | Thioredoxin reductase | / | 0.884 | |
| 3oc4 | FAD | Oxidoreductase, pyridine nucleotide-disulfide family | / | 0.875 | |
| 2yg5 | FAD | Putrescine oxidase | / | 0.872 | |
| 4cy8 | FDA | 2-hydroxybiphenyl-3-monooxygenase | / | 0.872 | |
| 3ab1 | FAD | Ferredoxin--NADP reductase | 1.18.1.2 | 0.863 | |
| 4gut | FAD | Lysine-specific histone demethylase 1B | 1 | 0.860 | |
| 5fs8 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.854 | |
| 4jq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.853 | |
| 2b9x | FAD | Putative aminooxidase | / | 0.852 | |
| 2bab | FAD | Putative aminooxidase | / | 0.852 | |
| 3icr | FAD | Coenzyme A disulfide reductase | / | 0.852 | |
| 2xdo | FAD | TetX family tetracycline inactivation enzyme | / | 0.841 | |
| 1ger | FAD | Glutathione reductase | 1.8.1.7 | 0.840 | |
| 1m6i | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.840 | |
| 1geu | FAD | Glutathione reductase | 1.8.1.7 | 0.837 | |
| 5fs7 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.837 | |
| 3ics | FAD | Coenzyme A disulfide reductase | / | 0.832 | |
| 3rha | FDA | Putrescine oxidase | / | 0.832 | |
| 4bk2 | FAD | Probable salicylate monooxygenase | / | 0.831 | |
| 4lii | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.831 | |
| 4x4j | FAD | Putative oxygenase | / | 0.826 | |
| 1gre | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.825 | |
| 3k7m | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.825 | |
| 4emw | FAD | Coenzyme A disulfide reductase | / | 0.824 | |
| 1zx9 | FAD | Mercuric reductase | 1.16.1.1 | 0.823 | |
| 4bv6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.821 | |
| 3ntd | FAD | FAD-dependent pyridine nucleotide-disulphide oxidoreductase | / | 0.820 | |
| 4fwf | FAD | Lysine-specific histone demethylase 1B | 1 | 0.819 | |
| 2b9y | FAD | Putative aminooxidase | / | 0.818 | |
| 2bac | FAD | Putative aminooxidase | / | 0.818 | |
| 2nvk | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.816 | |
| 4nte | FAD | DepH | / | 0.814 | |
| 1nhs | FAD | NADH peroxidase | 1.11.1.1 | 0.813 | |
| 3klj | FAD | NADH-rubredoxin oxidoreductase | 1.18.1.1 | 0.813 | |
| 1gsn | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.812 | |
| 2eq9 | FAD | Dihydrolipoyl dehydrogenase | / | 0.812 | |
| 2qa1 | FAD | PgaE | / | 0.812 | |
| 3bg7 | FAD | Pyranose 2-oxidase | / | 0.812 | |
| 5fs6 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.810 | |
| 1bwc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.809 | |
| 2yg3 | FAD | Putrescine oxidase | / | 0.809 | |
| 3fbs | FAD | Oxidoreductase | / | 0.809 | |
| 1zk7 | FAD | Mercuric reductase | 1.16.1.1 | 0.807 | |
| 5g3s | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.807 | |
| 1z6l | FAD | Polyamine oxidase FMS1 | / | 0.806 | |
| 4gcm | FAD | Thioredoxin reductase | 1.8.1.9 | 0.805 | |
| 2yg4 | FAD | Putrescine oxidase | / | 0.804 | |
| 4hb9 | FAD | Uncharacterized protein | / | 0.804 | |
| 2e1m | FAD | L-glutamate oxidase | / | 0.803 | |
| 4bjz | FAD | Probable salicylate monooxygenase | / | 0.803 | |
| 1gv4 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.802 | |
| 2gr0 | FAD | Ferredoxin reductase | / | 0.802 | |
| 2x8g | FAD | Thioredoxin glutathione reductase | / | 0.802 | |
| 5g3t | FDA | Flavin-dependent L-tryptophan oxidase VioA | / | 0.802 | |
| 1f3p | FAD | Ferredoxin reductase | / | 0.800 | |
| 3sqp | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.800 | |
| 4k5r | FAD | Oxygenase | / | 0.800 | |
| 2yg7 | FAD | Putrescine oxidase | / | 0.799 | |
| 4gus | FAD | Lysine-specific histone demethylase 1B | 1 | 0.798 | |
| 5er0 | FAD | Uncharacterized NAD(FAD)-dependent dehydrogenase | / | 0.797 | |
| 5dbj | FAD | FADH2-dependent halogenase PltA | / | 0.796 | |
| 1v59 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.795 | |
| 4j57 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.794 | |
| 2r9z | FAD | Glutathione amide reductase | / | 0.793 | |
| 3dgh | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.793 | |
| 1d7y | FAD | Ferredoxin reductase | / | 0.792 | |
| 4em3 | FAD | Coenzyme A disulfide reductase | / | 0.792 | |
| 2v6o | FAD | Thioredoxin glutathione reductase | / | 0.791 | |
| 4bk3 | FAD | Probable salicylate monooxygenase | / | 0.791 | |
| 5eow | FAD | 6-hydroxynicotinate 3-monooxygenase | 1.14.13.114 | 0.791 | |
| 4h4p | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.790 | |
| 2npx | FAD | NADH peroxidase | 1.11.1.1 | 0.789 | |
| 2yg6 | FAD | Putrescine oxidase | / | 0.789 | |
| 3k4c | FAD | Pyranose 2-oxidase | / | 0.789 | |
| 2gh5 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.788 | |
| 4gur | FAD | Lysine-specific histone demethylase 1B | 1 | 0.788 | |
| 1dnc | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.787 | |
| 2ign | FAD | Pyranose 2-oxidase | / | 0.787 | |
| 3oz2 | FAD | Digeranylgeranylglycerophospholipid reductase | / | 0.787 | |
| 1gra | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.786 | |
| 4eqs | FAD | Coenzyme A disulfide reductase | / | 0.786 | |
| 4fx9 | FAD | Coenzyme A disulfide reductase | 1.8.1.14 | 0.786 | |
| 3lsi | FAD | Pyranose 2-oxidase | / | 0.785 | |
| 4dsh | FDA | Uncharacterized protein | / | 0.785 | |
| 4ech | FAD | Polyamine oxidase FMS1 | / | 0.785 | |
| 4h4t | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.785 | |
| 2gqw | FAD | Ferredoxin reductase | / | 0.784 | |
| 3qfa | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.783 | |
| 3pl8 | FAD | Pyranose 2-oxidase | / | 0.782 | |
| 4j34 | FAD | Kynurenine 3-monooxygenase | / | 0.782 | |
| 4mih | FAD | Pyranose 2-oxidase | 1.1.3.10 | 0.782 | |
| 3r9u | FAD | Thioredoxin reductase | / | 0.781 | |
| 3bi5 | FAD | Polyamine oxidase FMS1 | / | 0.780 | |
| 3djg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.780 | |
| 3urh | FAD | Dihydrolipoyl dehydrogenase | / | 0.779 | |
| 4dsg | FAD | Uncharacterized protein | / | 0.778 | |
| 4h4z | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.778 | |
| 1nhr | FAD | NADH peroxidase | 1.11.1.1 | 0.777 | |
| 2q0k | FAD | Thioredoxin reductase | 1.8.1.9 | 0.777 | |
| 4h4r | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.777 | |
| 1ges | FAD | Glutathione reductase | 1.8.1.7 | 0.775 | |
| 3grs | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.774 | |
| 2a8x | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.773 | |
| 3nn6 | FB0 | 6-hydroxy-L-nicotine oxidase | / | 0.773 | |
| 4rpg | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.773 | |
| 3sz0 | FAD | Sulfide-quinone reductase | / | 0.772 | |
| 2b9w | FAD | Putative aminooxidase | / | 0.771 | |
| 4j31 | FAD | Kynurenine 3-monooxygenase | / | 0.771 | |
| 1grb | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.770 | |
| 2c3c | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.770 | |
| 2zbw | FAD | Ferredoxin--NADP reductase | / | 0.770 | |
| 3dk9 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.770 | |
| 4h4x | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.770 | |
| 4la1 | FAD | Thioredoxin glutathione reductase | / | 0.770 | |
| 1k4q | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.769 | |
| 3nix | FAD | Flavoprotein/dehydrogenase | / | 0.769 | |
| 5buk | FAD | FADH2-dependent halogenase | / | 0.769 | |
| 2igo | FAD | Pyranose 2-oxidase | / | 0.768 | |
| 2yr5 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.768 | |
| 3ish | FAD | Thioredoxin reductase | 1.8.1.9 | 0.768 | |
| 4hsu | FAD | Lysine-specific histone demethylase 1B | 1 | 0.768 | |
| 4jn9 | FAD | DepH | / | 0.768 | |
| 4nzh | FAD | L-ornithine N(5)-monooxygenase | / | 0.768 | |
| 2gmh | FAD | Electron transfer flavoprotein-ubiquinone oxidoreductase, mitochondrial | 1.5.5.1 | 0.766 | |
| 3rp8 | FAD | FAD-dependent urate hydroxylase | / | 0.765 | |
| 4eqx | FAD | Coenzyme A disulfide reductase | / | 0.765 | |
| 4b1b | FAD | Thioredoxin reductase | 1.8.1.9 | 0.764 | |
| 1grh | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.763 | |
| 1npx | FAD | NADH peroxidase | 1.11.1.1 | 0.763 | |
| 3dk4 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.763 | |
| 3lsh | FAD | Pyranose 2-oxidase | / | 0.763 | |
| 4h4v | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.763 | |
| 5j60 | FAD | Thioredoxin reductase | / | 0.763 | |
| 1qo8 | FAD | Fumarate reductase flavoprotein subunit | / | 0.762 | |
| 2ba9 | FAD | Putative aminooxidase | / | 0.761 | |
| 2bry | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.761 | |
| 2qa2 | FAD | Polyketide oxygenase CabE | / | 0.761 | |
| 4a6n | FAD | TetX family tetracycline inactivation enzyme | / | 0.761 | |
| 4k2x | FAD | Polyketide oxygenase/hydroxylase | / | 0.761 | |
| 2dw4 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.760 | |
| 2vou | FAD | 2,6-dihydroxypyridine 3-monooxygenase | 1.14.13.10 | 0.760 | |
| 3ef6 | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.760 | |
| 4i58 | FAD | Cyclohexylamine Oxidase | / | 0.760 | |
| 1grg | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.759 | |
| 3f8d | FAD | NADH oxidase/thioredoxin reductase | / | 0.759 | |
| 3dk8 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.758 | |
| 4b69 | FAD | L-ornithine N(5)-monooxygenase | / | 0.758 | |
| 1pdh | FAS | p-hydroxybenzoate hydroxylase | / | 0.757 | |
| 2h94 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.757 | |
| 3djj | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.757 | |
| 4a65 | FAD | Thioredoxin reductase | / | 0.757 | |
| 3t37 | FAD | Pyridoxine 4-oxidase | / | 0.756 | |
| 2eq7 | FAD | Dihydrolipoyl dehydrogenase | / | 0.755 | |
| 2x8h | FAD | Thioredoxin glutathione reductase | / | 0.755 | |
| 4m52 | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.755 | |
| 1ju2 | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.754 | |
| 1q1w | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.754 | |
| 3lzw | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.754 | |
| 4em4 | FAD | Coenzyme A disulfide reductase | / | 0.754 | |
| 1gte | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.753 | |
| 4eqw | FAD | Coenzyme A disulfide reductase | / | 0.753 | |
| 2vvl | FAD | Monoamine oxidase N | 1.4.3.4 | 0.752 | |
| 4g6h | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.752 | |
| 4nev | FAD | Trypanothione reductase | / | 0.752 | |
| 4u8p | FDA | UDP-galactopyranose mutase | / | 0.752 | |
| 1ps9 | FAD | 2,4-dienoyl-CoA reductase | 1.3.1.34 | 0.751 | |
| 2wow | FAD | Trypanothione reductase | / | 0.751 | |
| 4gap | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.751 | |
| 4gdp | FAD | Polyamine oxidase FMS1 | / | 0.751 | |
| 4ntd | FAD | Thioredoxin reductase | / | 0.751 | |
| 4wct | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.751 | |
| 1bzl | FAD | Trypanothione reductase | 1.8.1.12 | 0.750 | |
| 3utf | FDA | UDP-galactopyranose mutase | / | 0.750 | |
| 4g9k | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.750 | |
| 4o5q | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.750 | |
| 3rnm | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.749 | |
| 2yvf | FAD | Ferredoxin reductase | / | 0.748 | |
| 4u8j | FDA | UDP-galactopyranose mutase | / | 0.748 | |
| 5i39 | FAD | L-amino acid deaminase | / | 0.747 | |
| 2jb2 | FAD | L-amino acid oxidase | / | 0.746 | |
| 3k7t | FAD | 6-hydroxy-L-nicotine oxidase | / | 0.746 | |
| 3lad | FAD | Dihydrolipoyl dehydrogenase | / | 0.746 | |
| 4emj | FAD | Toluene 1,2-dioxygenase system ferredoxin--NAD(+) reductase component | 1.18.1.3 | 0.746 | |
| 4fwe | FAD | Lysine-specific histone demethylase 1B | 1 | 0.746 | |
| 4j36 | FAD | Kynurenine 3-monooxygenase | / | 0.746 | |
| 1cc2 | FAD | Cholesterol oxidase | 1.1.3.6 | 0.745 | |
| 4a99 | FAD | TetX family tetracycline inactivation enzyme | / | 0.745 | |
| 2jae | FAD | L-amino acid oxidase | / | 0.744 | |
| 4mo2 | FAD | UDP-galactopyranose mutase | / | 0.744 | |
| 4u8k | FDA | UDP-galactopyranose mutase | / | 0.743 | |
| 2gr3 | FAD | Ferredoxin reductase | / | 0.742 | |
| 2w0h | FAD | Trypanothione reductase | / | 0.742 | |
| 4gr1 | FAD | Glutathione reductase, mitochondrial | 1.8.1.7 | 0.742 | |
| 4opg | FDA | Conserved Archaeal protein | / | 0.742 | |
| 4u8n | FDA | UDP-galactopyranose mutase | / | 0.742 | |
| 4up3 | FAD | Thioredoxin reductase | / | 0.742 | |
| 1mok | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.741 | |
| 2q0l | FAD | Thioredoxin reductase | 1.8.1.9 | 0.741 | |
| 3k30 | ADP | Histamine dehydrogenase | / | 0.741 | |
| 4fwj | FAD | Lysine-specific histone demethylase 1B | 1 | 0.741 | |
| 4u8o | FDA | UDP-galactopyranose mutase | / | 0.741 | |
| 1h7w | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.740 | |
| 1e1n | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.739 | |
| 3alj | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.739 | |
| 2jk6 | FAD | Trypanothione reductase | / | 0.738 | |
| 2ym1 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.738 | |
| 3bi2 | FAD | Polyamine oxidase FMS1 | / | 0.738 | |
| 4eqr | FAD | Coenzyme A disulfide reductase | / | 0.737 | |
| 1f8w | FAD | NADH peroxidase | 1.11.1.1 | 0.736 | |
| 3nlc | FAD | Uncharacterized protein | / | 0.736 | |
| 3utg | FDA | UDP-galactopyranose mutase | / | 0.736 | |
| 1fec | FAD | Trypanothione reductase | 1.8.1.12 | 0.735 | |
| 3all | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.735 | |
| 3we0 | FAD | Lysine 2-monooxygenase | / | 0.735 | |
| 3int | FDA | UDP-galactopyranose mutase | 5.4.99.9 | 0.734 | |
| 1gth | FAD | Dihydropyrimidine dehydrogenase [NADP(+)] | 1.3.1.2 | 0.733 | |
| 2whd | FAD | Thioredoxin reductase | / | 0.733 | |
| 3hdy | FAD | UDP-galactopyranose mutase | / | 0.733 | |
| 3lzx | FAD | Ferredoxin--NADP reductase 2 | 1.18.1.2 | 0.733 | |
| 1f8r | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.732 | |
| 1nhq | FAD | NADH peroxidase | 1.11.1.1 | 0.732 | |
| 2gr1 | FAD | Ferredoxin reductase | / | 0.732 | |
| 2tpr | FAD | Trypanothione reductase | 1.8.1.12 | 0.732 | |
| 2yr4 | FAD | Phenylalanine 2-monooxygenase precursor | 1.13.12.9 | 0.732 | |
| 3uth | FDA | UDP-galactopyranose mutase | / | 0.732 | |
| 4a5l | FAD | Thioredoxin reductase | / | 0.732 | |
| 4guv | FAD | TetX family tetracycline inactivation enzyme | / | 0.732 | |
| 1get | FAD | Glutathione reductase | 1.8.1.7 | 0.731 | |
| 3atq | FDA | Conserved Archaeal protein | / | 0.731 | |
| 3dh9 | FAD | Thioredoxin reductase 1, mitochondrial | 1.8.1.9 | 0.731 | |
| 1tdf | FAD | Thioredoxin reductase | 1.8.1.9 | 0.730 | |
| 2tmd | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.730 | |
| 3qj4 | FAD | Renalase | / | 0.730 | |
| 4u8m | FDA | UDP-galactopyranose mutase | / | 0.730 | |
| 2c7g | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.729 | |
| 2fje | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.729 | |
| 2x3n | FAD | Probable FAD-dependent monooxygenase | / | 0.729 | |
| 3fpz | AHZ | Thiamine thiazole synthase | / | 0.729 | |
| 3zdn | FAD | Monoamine oxidase N | 1.4.3.4 | 0.729 | |
| 1nhp | FAD | NADH peroxidase | 1.11.1.1 | 0.728 | |
| 1xpq | FAD | Polyamine oxidase FMS1 | / | 0.728 | |
| 3gdp | FAD | (R)-mandelonitrile lyase 2 | 4.1.2.10 | 0.728 | |
| 4g73 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.728 | |
| 2jb1 | FAD | L-amino acid oxidase | / | 0.726 | |
| 4j2w | FAD | Kynurenine 3-monooxygenase | / | 0.726 | |
| 1lqu | FAD | NADPH-ferredoxin reductase FprA | 1.18.1.2 | 0.725 | |
| 1d4d | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.724 | |
| 2dki | FAD | 3-hydroxybenzoate 4-monooxygenase | 1.14.13.23 | 0.724 | |
| 2yqu | FAD | Dihydrolipoyl dehydrogenase | / | 0.724 | |
| 2cdu | FAD | NADH oxidase | / | 0.722 | |
| 3kpf | FAD | Polyamine oxidase | 1.5.3.14 | 0.722 | |
| 4rsl | FAD | Fructosyl peptide oxidase | / | 0.722 | |
| 4wx1 | FDA | UDP-galactopyranose mutase | / | 0.722 | |
| 1d7l | RFL | p-hydroxybenzoate hydroxylase | / | 0.721 | |
| 1mo9 | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.720 | |
| 3lb8 | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.720 | |
| 4j33 | FAD | Kynurenine 3-monooxygenase | / | 0.720 | |
| 4opc | FDA | Conserved Archaeal protein | / | 0.719 | |
| 3dgz | FAD | Thioredoxin reductase 2, mitochondrial | 1.8.1.9 | 0.718 | |
| 3kve | FAD | L-amino-acid oxidase | / | 0.718 | |
| 4g6g | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.718 | |
| 1jeh | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.717 | |
| 1k0l | FAD | p-hydroxybenzoate hydroxylase | / | 0.717 | |
| 3ada | NAD | Subunit alpha of sarocosine oxidase | / | 0.717 | |
| 3cty | FAD | Probable thioredoxin reductase | / | 0.717 | |
| 1joa | FAD | NADH peroxidase | 1.11.1.1 | 0.715 | |
| 4mok | FAD | Pyranose 2-oxidase | / | 0.715 | |
| 4xwz | FAD | Fructosyl amine:oxygen oxidoreductase | / | 0.715 | |
| 1q1r | FAD | Putidaredoxin reductase | 1.18.1.5 | 0.714 | |
| 1yqz | FAD | Coenzyme A disulfide reductase | / | 0.714 | |
| 2qae | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.714 | |
| 3cnt | FAD | Polyamine oxidase FMS1 | / | 0.714 | |
| 3fg2 | FAD | Putative rubredoxin reductase | / | 0.714 | |
| 4opi | FDA | Conserved Archaeal protein | / | 0.714 | |
| 4opu | FDA | Conserved Archaeal protein | / | 0.714 | |
| 1zy8 | FAD | Dihydrolipoyl dehydrogenase, mitochondrial | 1.8.1.4 | 0.713 | |
| 2c4c | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.713 | |
| 1djn | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.712 | |
| 2zzc | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.712 | |
| 3jsk | AHZ | Thiamine thiazole synthase | / | 0.712 | |
| 3lsm | SFD | Pyranose 2-oxidase | / | 0.712 | |
| 3vqr | FAD | Putative oxidoreductase | / | 0.712 | |
| 4txi | FAD | [F-actin]-methionine sulfoxide oxidase MICAL1 | 1.14.13 | 0.712 | |
| 4ysh | FAD | Glycine oxidase | / | 0.712 | |
| 1k0j | FAD | p-hydroxybenzoate hydroxylase | / | 0.711 | |
| 4h4u | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.711 | |
| 4tm4 | FDA | KtzI | / | 0.711 | |
| 4x9n | FAD | Uncharacterized protein MG039 homolog | / | 0.711 | |
| 2hko | FAD | Lysine-specific histone demethylase 1A | 1 | 0.710 | |
| 1cbo | FAD | Cholesterol oxidase | 1.1.3.6 | 0.709 | |
| 1feb | FAD | Trypanothione reductase | 1.8.1.12 | 0.708 | |
| 1gxf | FAD | Trypanothione reductase | 1.8.1.12 | 0.708 | |
| 1xdi | FAD | NAD(P)H dehydrogenase (quinone) | / | 0.708 | |
| 4h50 | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.708 | |
| 4yac | NAI | C alpha-dehydrogenase | / | 0.708 | |
| 3cox | FAD | Cholesterol oxidase | 1.1.3.6 | 0.707 | |
| 3mj4 | FAD | UDP-galactopyranose mutase | / | 0.707 | |
| 4gde | FDA | UDP-galactopyranose mutase | / | 0.707 | |
| 1tde | FAD | Thioredoxin reductase | 1.8.1.9 | 0.706 | |
| 2eq8 | FAD | Dihydrolipoyl dehydrogenase | / | 0.706 | |
| 4dna | FAD | Probable glutathione reductase | / | 0.706 | |
| 4kpr | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.706 | |
| 1w4x | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.705 | |
| 2c3d | FAD | 2-oxopropyl-CoM reductase, carboxylating | 1.8.1.5 | 0.705 | |
| 2cfy | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.705 | |
| 4j56 | FAD | Thioredoxin reductase 2 | 1.8.1.9 | 0.705 | |
| 3ad9 | FAD | Subunit beta of sarcosine oxidase | / | 0.704 | |
| 3cn8 | FAD | Polyamine oxidase FMS1 | / | 0.704 | |
| 4ntc | FAD | Thioredoxin reductase gliT | / | 0.704 | |
| 4opd | FDA | Conserved Archaeal protein | / | 0.704 | |
| 3gd3 | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.703 | |
| 1b4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.702 | |
| 1e6e | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.702 | |
| 3ukk | FAD | UDP-galactopyranose mutase | / | 0.702 | |
| 3uox | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.702 | |
| 4u8l | FDA | UDP-galactopyranose mutase | / | 0.702 | |
| 1cl0 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.701 | |
| 2fjb | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.701 | |
| 2fjd | SFD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.701 | |
| 3f8p | NAD | NADH oxidase/thioredoxin reductase | / | 0.701 | |
| 3fmw | FAD | Oxygenase | / | 0.701 | |
| 4bur | FAD | Apoptosis-inducing factor 1, mitochondrial | 1.1.1 | 0.701 | |
| 1fl2 | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.700 | |
| 4ccq | FAD | Thioredoxin reductase | / | 0.700 | |
| 3sfe | FAD | Succinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial | / | 0.699 | |
| 4h4w | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.699 | |
| 3axb | FAD | Putative oxidoreductase | / | 0.698 | |
| 3g5q | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.698 | |
| 4icy | FAD | PgaE | / | 0.698 | |
| 4rpj | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.698 | |
| 1o94 | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.697 | |
| 1rsg | FAD | Polyamine oxidase FMS1 | / | 0.697 | |
| 3uov | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.697 | |
| 4h4y | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.697 | |
| 3cnd | FAD | Polyamine oxidase FMS1 | / | 0.696 | |
| 4h4s | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.696 | |
| 4ynt | FDA | Glucose oxidase, putative | / | 0.696 | |
| 1h83 | FAD | Polyamine oxidase | 1.5.3.14 | 0.695 | |
| 4h4q | FAD | Biphenyl dioxygenase ferredoxin reductase subunit | / | 0.695 | |
| 1jnr | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.694 | |
| 1phh | FAD | p-hydroxybenzoate hydroxylase | / | 0.694 | |
| 1tdo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.694 | |
| 3kkj | FAD | Renalase | / | 0.694 | |
| 4opt | FDA | Conserved Archaeal protein | / | 0.694 | |
| 5br7 | FAD | UDP-galactopyranose mutase | / | 0.694 | |
| 2rab | FAD | Glutathione amide reductase | / | 0.693 | |
| 3syi | FAD | Sulfide-quinone reductase | / | 0.693 | |
| 4jdr | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.693 | |
| 4ykg | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.693 | |
| 1n4v | FAD | Cholesterol oxidase | 1.1.3.6 | 0.692 | |
| 4guu | FA9 | Lysine-specific histone demethylase 1B | 1 | 0.692 | |
| 4u8i | FDA | UDP-galactopyranose mutase | / | 0.692 | |
| 1e1l | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.691 | |
| 1ryi | FAD | Glycine oxidase | 1.4.3.19 | 0.691 | |
| 1y56 | FAD | 382aa long hypothetical sarcosine oxidase | / | 0.690 | |
| 4d7e | FAD | Putative lysine-N-oxygenase | / | 0.690 | |
| 1trb | FAD | Thioredoxin reductase | 1.8.1.9 | 0.689 | |
| 2uxx | FAJ | Lysine-specific histone demethylase 1A | 1 | 0.689 | |
| 2xyo | FAD | TetX family tetracycline inactivation enzyme | / | 0.688 | |
| 3m12 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.688 | |
| 1jnz | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.687 | |
| 4tm3 | FAD | KtzI | / | 0.687 | |
| 2fja | FAD | Adenylylsulfate reductase, subunit A (AprA) | / | 0.686 | |
| 3atr | FDA | Conserved Archaeal protein | / | 0.686 | |
| 4yry | FAD | Glutamate synthase, beta subunit | / | 0.686 | |
| 5l3d | FAD | Lysine-specific histone demethylase 1A | 1 | 0.686 | |
| 3p9u | FAD | TetX family tetracycline inactivation enzyme | / | 0.685 | |
| 4rek | FAD | Cholesterol oxidase | 1.1.3.6 | 0.685 | |
| 2du8 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.684 | |
| 3m0o | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.684 | |
| 3pvc | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | / | 0.684 | |
| 1d4c | FAD | Fumarate reductase flavoprotein subunit | 1.3.5.4 | 0.683 | |
| 4h2p | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.683 | |
| 4opl | FDA | Conserved Archaeal protein | / | 0.683 | |
| 4z2t | FAD | 2-hydroxybiphenyl-3-monooxygenase | / | 0.683 | |
| 3uoy | FAD | 2-oxo-Delta(3)-4,5,5-trimethylcyclopentenylacetyl-CoA monooxygenase | 1.14.13.160 | 0.682 | |
| 5hsa | FAS | Alcohol oxidase 1 | 1.1.3.13 | 0.682 | |
| 2bi7 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.681 | |
| 3qvr | FAD | Glucose oxidase | 1.1.3.4 | 0.681 | |
| 4fk1 | FAD | Putative thioredoxin reductase | / | 0.681 | |
| 1cjc | FAD | NADPH:adrenodoxin oxidoreductase, mitochondrial | 1.18.1.6 | 0.680 | |
| 3kpk | FAD | Sulfide-quinone reductase | / | 0.680 | |
| 4udr | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.680 | |
| 1lvl | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.679 | |
| 4gav | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.679 | |
| 4xxg | FAD | Cholesterol oxidase | 1.1.3.6 | 0.679 | |
| 1yy5 | FAD | Polyamine oxidase FMS1 | / | 0.678 | |
| 2z6c | FMN | Phototropin-1 | 2.7.11.1 | 0.678 | |
| 3awi | FAD | tRNA 5-methylaminomethyl-2-thiouridine biosynthesis bifunctional protein MnmC | 1.5 | 0.678 | |
| 3m13 | FAD | Monomeric sarcosine oxidase | 1.5.3.1 | 0.678 | |
| 3t14 | FAD | Sulfide-quinone reductase | / | 0.678 | |
| 4z26 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.678 | |
| 1djq | ADP | Trimethylamine dehydrogenase | 1.5.8.2 | 0.677 | |
| 1tdn | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.677 | |
| 3dme | FAD | Putative conserved exported protein | / | 0.677 | |
| 3lxd | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.677 | |
| 4o5u | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.677 | |
| 4xbf | FAD | Lysine-specific histone demethylase 1A | 1 | 0.677 | |
| 2a87 | FAD | Thioredoxin reductase | 1.8.1.9 | 0.676 | |
| 2hqm | FAD | Glutathione reductase | 1.8.1.7 | 0.676 | |
| 2y48 | FAD | Lysine-specific histone demethylase 1A | 1 | 0.676 | |
| 1lpf | FAD | Dihydrolipoyl dehydrogenase | 1.8.1.4 | 0.675 | |
| 2v3a | FAD | Rubredoxin-NAD(+) reductase | 1.18.1.1 | 0.675 | |
| 3hdy | FDA | UDP-galactopyranose mutase | / | 0.675 | |
| 5hhf | FDA | UDP-galactopyranose mutase | / | 0.674 | |
| 3f8r | NAP | NADH oxidase/thioredoxin reductase | / | 0.673 | |
| 3ic9 | FAD | Putative dihydrolipoamide dehydrogenase | / | 0.673 | |
| 3bnk | FMN | Flavoredoxin | / | 0.672 | |
| 4mo2 | FDA | UDP-galactopyranose mutase | / | 0.672 | |
| 3c96 | FAD | Flavin-containing monooxygenase | / | 0.671 | |
| 4u2l | SFD | Cholesterol oxidase | 1.1.3.6 | 0.671 | |
| 2ym2 | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.670 | |
| 2xvi | FAD | Putative flavin-containing monooxygenase | / | 0.669 | |
| 3k4n | FAD | Pyranose 2-oxidase | / | 0.669 | |
| 1cf3 | FAD | Glucose oxidase | 1.1.3.4 | 0.668 | |
| 2gqf | FAD | Uncharacterized protein HI_0933 | / | 0.668 | |
| 4c3y | FAD | 3-ketosteroid dehydrogenase | / | 0.668 | |
| 1gpe | FAD | Glucose oxidase | 1.1.3.4 | 0.667 | |
| 1tdk | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.667 | |
| 2cvj | FAD | Thioredoxin reductase related protein | / | 0.667 | |
| 4g6h | NAI | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.667 | |
| 4xrg | NAD | Homospermidine synthase | 2.5.1.44 | 0.666 | |
| 1typ | FAD | Trypanothione reductase | 1.8.1.12 | 0.665 | |
| 4g74 | FAD | Rotenone-insensitive NADH-ubiquinone oxidoreductase, mitochondrial | 1.6.5.9 | 0.665 | |
| 4plp | NAD | Homospermidine synthase | 2.5.1.44 | 0.665 | |
| 4ykf | FAD | Alkyl hydroperoxide reductase subunit F | 1.8.1 | 0.665 | |
| 5eb5 | FAD | (R)-mandelonitrile lyase 1 | 4.1.2.10 | 0.665 | |
| 1i8t | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.664 | |
| 1n4w | FAD | Cholesterol oxidase | 1.1.3.6 | 0.664 | |
| 1v0j | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.664 | |
| 3t2k | FAD | Sulfide-quinone reductase | / | 0.664 | |
| 4cbq | FAD | Thioredoxin reductase | / | 0.663 | |
| 4tm1 | FDA | KtzI | / | 0.663 | |
| 1ve9 | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.662 | |
| 2bi8 | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.662 | |
| 2j3n | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.662 | |
| 2zz0 | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.662 | |
| 1ng3 | FAD | Glycine oxidase | 1.4.3.19 | 0.661 | |
| 3ukf | FDA | UDP-galactopyranose mutase | / | 0.661 | |
| 1fea | FAD | Trypanothione reductase | 1.8.1.12 | 0.660 | |
| 1reo | FAD | L-amino-acid oxidase | 1.4.3.2 | 0.660 | |
| 3kyb | FAD | UDP-galactopyranose mutase | 5.4.99.9 | 0.660 | |
| 3l8k | ADP | Dihydrolipoamide dehydrogenase (PdhD-3) | / | 0.660 | |
| 3qvp | FAD | Glucose oxidase | 1.1.3.4 | 0.660 | |
| 4udq | FAD | 5-(hydroxymethyl)furfural oxidase | / | 0.660 | |
| 1c0l | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.659 | |
| 1n1p | FAD | Cholesterol oxidase | 1.1.3.6 | 0.659 | |
| 1tyt | FAD | Trypanothione reductase | 1.8.1.12 | 0.659 | |
| 3ukl | FAD | UDP-galactopyranose mutase | / | 0.659 | |
| 2ylt | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.657 | |
| 3gwd | FAD | Cyclohexanone monooxygenase | / | 0.657 | |
| 3if9 | FAD | Glycine oxidase | 1.4.3.19 | 0.657 | |
| 2i0z | FAD | NAD(FAD)-utilizing dehydrogenases | / | 0.656 | |
| 3g5s | FAD | Methylenetetrahydrofolate--tRNA-(uracil-5-)-methyltransferase TrmFO | / | 0.656 | |
| 1ijh | FAD | Cholesterol oxidase | 1.1.3.6 | 0.655 | |
| 3he3 | FAD | UDP-galactopyranose mutase | / | 0.655 | |
| 3nyc | FAD | FAD-dependent catabolic D-arginine dehydrogenase DauA | / | 0.655 | |
| 4qi4 | FAD | Cellobiose dehydrogenase | / | 0.655 | |
| 4u2s | FDA | Cholesterol oxidase | 1.1.3.6 | 0.655 | |
| 4z24 | FAD | Putative GMC-type oxidoreductase R135 | 1 | 0.655 | |
| 1b8s | FAD | Cholesterol oxidase | 1.1.3.6 | 0.654 | |
| 2cul | FAD | GidA-related protein | / | 0.654 | |
| 2r0c | FAD | Putative FAD-monooxygenase | / | 0.654 | |
| 4yjd | FAD | D-amino-acid oxidase | 1.4.3.3 | 0.654 | |
| 2gew | FAD | Cholesterol oxidase | 1.1.3.6 | 0.653 | |
| 2vyv | NAD | Glyceraldehyde-3-phosphate dehydrogenase A | / | 0.653 | |
| 2ylr | FAD | Phenylacetone monooxygenase | 1.14.13.92 | 0.653 | |
| 3alm | FAD | 2-methyl-3-hydroxypyridine-5-carboxylic acid oxygenase | / | 0.653 | |
| 3lov | FAD | Protoporphyrinogen oxidase | / | 0.653 | |
| 3qfb | FAD | Thioredoxin reductase 1, cytoplasmic | 1.8.1.9 | 0.653 | |
| 1h81 | FAD | Polyamine oxidase | 1.5.3.14 | 0.652 | |
| 2ywl | FAD | Thioredoxin reductase related protein | / | 0.652 | |
| 3gyj | FAD | Cholesterol oxidase | 1.1.3.6 | 0.652 | |
| 3ka7 | FAD | Putative oxidoreductase | / | 0.652 | |
| 4nwz | FAD | FAD-dependent pyridine nucleotide-disulfide oxidoreductase | / | 0.652 | |
| 1pkv | RBF | Riboflavin synthase | 2.5.1.9 | 0.651 | |
| 3a27 | SAM | tRNA(Phe) (4-demethylwyosine(37)-C(7)) aminocarboxypropyltransferase | / | 0.651 | |
| 4c3x | FAD | 3-ketosteroid dehydrogenase | / | 0.651 | |
| 1ylu | FMN | Oxygen-insensitive NAD(P)H nitroreductase | / | 0.650 | |
| 2i9k | SAH | Modification methylase HhaI | 2.1.1.37 | 0.650 | |
| 3gyi | FAD | Cholesterol oxidase | 1.1.3.6 | 0.650 | |
| 4hia | FMN | LOV protein | / | 0.650 | |
| 4u2t | FAD | Cholesterol oxidase | 1.1.3.6 | 0.650 |